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Khirurgiia (Mosk) 2022 (7):24-32

Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.

Objective: To analyze treatment outcomes in patients with acute appendicitis complicated by widespread peritonitis.

Material And Methods: The study included 165 patients acute appendicitis complicated by widespread peritonitis. Inclusion criteria: acute appendicitis complicated by widespread peritonitis MIP grade 1-2 in reactive or toxic phase (grading system by Simonyan K. Read More

Can J Anaesth 2022 Jun 29. Epub 2022 Jun 29.

Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.

Purpose: Postdischarge opioid prescriptions are reportedly much higher in Canada than in other countries. To assess potentially contributing factors, we examined trends after abdominal and orthopedic surgeries in British Columbia (BC).

Methods: Using the BC Ministry of Health's databases on physician billings, hospital discharge abstracts, and medication dispensations in community pharmacies for the period 2003-2016, we assembled a cohort of 263,056 patients who received laparoscopic appendectomy (LA, 11%), laparoscopic cholecystectomy (LC, 30%), open inguinal or femoral hernia repair (IHR, 20%), total hip arthroplasty (THA, 18%), or total knee arthroplasty (TKA, 22%). Read More

Front Surg 2022 8;9:919744. Epub 2022 Jun 8.

Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery, University Hospital, University of Wuerzburg, Wuerzburg, Germany.

Introduction: Surgical site infections (SSIs) are one of the most common postoperative complications after appendectomy leading to recurrent surgery, prolonged hospital stay, and the use of antibiotics. Numerous studies and meta-analyses have been published on the effect of open versus conventional laparoscopic appendectomy (CLA) reporting faster postoperative recovery and less postoperative pain for CLA. A development from CLA has been the single-port appendectomy (SPA), associated with a better cosmesis but seemingly having a higher risk of wound infections. Read More

Aging Clin Exp Res 2022 Jun 20. Epub 2022 Jun 20.

Division of Gastroenterology and Hepatology, University of Maryland, 22 S Greene St, Baltimore, MD, 21201, USA.

Background: The presence of clinical frailty can pose an escalated risk toward surgical outcomes including in cases that involve minimally invasive procedures. Given this premise, we evaluate the effects of frailty on post-appendectomy outcomes using a national in-hospital registry.

Methods: 2011-2017 National Inpatient Sample was used to isolate inpatient appendectomy cases; the population as stratified using Johns Hopkins ACG clinical frailty, expressed as either binary or ternary (prefrailty, frailty, and without frailty) indicators. Read More

Biomed Rep 2022 Jul 10;17(1):55. Epub 2022 May 10.

Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, P.R. China.

Appendiceal mucocele is a rare disease. Due to the lack of specific clinical symptoms, and the high misdiagnosis rate before operation, in the present study, the clinical data were assessed to determine a potential basis for the diagnosis and treatment of appendiceal mucocele. The clinical data of 3,071 patients with appendicitis admitted between January 2014 and July 2021, including 9 patients with appendiceal mucoceles were retrospectively analyzed. Read More

Surgery 2022 Jun 12. Epub 2022 Jun 12.

Department of Surgery, Oakland University William Beaumont School of Medicine, Royal Oak, MI. Electronic address:

Background: Clostridioides difficile infection can be a significant complication in surgical patients. The purpose of this study was to describe the incidence and impact on outcomes of Clostridioides difficile infection in adult patients after appendectomy.

Methods: The American College of Surgeons National Surgical Quality Improvement Program data set was used to identify all patients with the primary procedure code of appendectomy between 2016 and 2018. Read More

Zentralbl Chir 2022 Jun 15;147(3):244-248. Epub 2022 Jun 15.

Klinik für Viszeral-, Allgemeine-, Tumor- und Transplantationschirurgie, Universitätsklinikum Köln, Koln, Deutschland.

With an incidence of 80%, neuroendocrine neoplasia (NEN) is the most common neoplasia of the appendix. In most cases, these tumours are diagnosed as an incidental finding after appendectomy with suspected appendicitis. They are usually highly differentiated neuroendocrine tumours. Read More

Surg Open Sci 2022 Jul 20;9:64-68. Epub 2022 May 20.

Department of Surgery, Dr Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.

Background: There are insufficient data from Saudi Arabia regarding appendectomy outcomes and hospital length of stay. Further, there is a need to compare the length of stay of Saudi patients and the literature. The purpose is to evaluate the surgical outcomes and hospital length of stay for complicated appendicitis and simple appendicitis. Read More

BJS Open 2022 May;6(3)

Department of Gastrointestinal Surgery, Stavanger University Hospital, Stavanger, Norway.

Background: Surgical training is aimed towards entrusted professional activity to obtain operative independence. Laparoscopic appendicectomy is performed early in training but except for simulators, real-life evaluation towards proficiency is scarce. The aim of this study was to model how each consecutive step may impact on the overall proficiency score for surgical trainees performing laparoscopic appendicectomy. Read More

Cureus 2022 Apr 30;14(4):e24631. Epub 2022 Apr 30.

General Surgery, Faculty of Medicine Mersin University, Mersin, TUR.

Background The coronavirus disease 2019 (COVID-19) pandemic has changed the lives and habits of people all over the world. In this study, it was planned to investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA), morbidity and mortality. Methods The data of patients who were operated on with the diagnosis of AA in our clinic between March 2019 and March 2021, divided into pre-COVID and post-COVID periods, were analyzed. Read More

Med J Malaysia 2022 05;77(3):331-337

Ng Teng Fong General Hospital, Department of Surgery, Jurong Health Campus, National University Health System, Singapore.

Introduction: Acute appendicitis is one of the most common causes of intra-abdominal emergency surgery worldwide. This study was conducted to contribute to global databases by presenting data from our institution, which consist of multi-racial population. We aimed to evaluate the presentation, diagnosis, and management of acute appendicitis and post-operative outcome in our institution and evaluate the risks factors associated with severe complications and prolonged length of stay (LOS). Read More

Ann Med Surg (Lond) 2022 May 13;77:103603. Epub 2022 Apr 13.

Division of Gastroenterology and Liver Disease, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.

Introduction: Acute appendicitis is one of the leading causes of acute abdominal pain and surgical emergency. Stump appendicitis is a known complication of appendectomy whereby a retained appendiceal tip serves as a nidus for recurrent bouts of inflammation. Nevertheless, full-blown appendicitis of the vermiform appendix after a prior appendectomy remains a diagnostic conundrum. Read More

World J Emerg Surg 2022 05 26;17(1):26. Epub 2022 May 26.

Department of Anorectal Surgery, The First Hospital of China Medical University, Shenyang, 110001, Liaoning, China.

Background: This paper compares the postoperative recovery of patients with acute appendicitis (AA) after laparoscopic appendectomy (LA) and open appendectomy (OA), aiming to determine the optimal diagnosis and treatment plan for appendectomy.

Methods: Related literature was retrieved from PubMed, Web of Science, Embase, CNKI and Wanfang databases. Articles on LA and OA for AA published between 2010 and 2021 were selected to extract data. Read More

J Minim Invasive Surg 2021 Jun;24(2):68-75

Department of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: Acute appendicitis is the most common nonobstetric indication for surgical intervention during pregnancy. In the argument of the optimal surgical approach to acute appendicitis in pregnancy, laparoscopy seems to be won with a similar complication rate and shorter postoperative recovery than open. We aimed to compare perioperative outcomes of appendectomy in pregnant and nonpregnant women in the totally laparoscopic age. Read More

Pan Afr Med J 2022 4;41:178. Epub 2022 Mar 4.

Cheikh Anta Diop University, Dakar, Senegal.

Mesenteric pseuodycst is a very rare benign childhood tumor, accounting for less than 1 out of 250,000 hospital admissions. We here report a case of giant mesenteric pseudocyst incidentally detected in a 11-year-old boy with acute appendicitis. He complained of persistent abdominal pain for the past 48 hours. Read More

World J Surg 2022 Aug 30;46(8):1849-1854. Epub 2022 Apr 30.

Department of Surgery, Aga Khan University Hospital, PO BOX: 47800, Karachi, Pakistan.

Background: In view of importance for competency-based education (CBE), we undertook a self-study to elicit the available operative surgical workload and supervision for residents in the general surgical residency program at the teaching hospital in Karachi.

Methodology: This was a cross-sectional study spanning a 5-year period between January 2015 and December 2019. The numbers of surgical residents during this period were identified. Read More

BMJ Open 2022 05 2;12(5):e057793. Epub 2022 May 2.

Department of Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

Introduction: Emerging evidence has shown that an antibiotic first strategy is a viable treatment option for uncomplicated acute appendicitis (AA). Although there has recently been an interest and increase in the use of antibiotics as the primary strategy for treating uncomplicated AA, there is no consensus regarding the optimum antibiotic regimen. In particular, the long-term outcomes of different antibiotic regimens, such as the recurrence rate, still lack evidence. Read More

JAMA Netw Open 2022 May 2;5(5):e229720. Epub 2022 May 2.

Department of Pediatric Surgery, Children's Mercy-Kansas City, Kansas City, Missouri.

JAMA Netw Open 2022 May 2;5(5):e229712. Epub 2022 May 2.

Center for Surgical Outcomes Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus.

Importance: The factors associated with the failure of nonoperative management of appendicitis and the differences in patient-reported outcomes between successful and unsuccessful nonoperative management remain unknown.

Objectives: To investigate factors associated with the failure of nonoperative management of appendicitis and compare patient-reported outcomes between patients whose treatment succeeded and those whose treatment failed.

Design, Setting, And Participants: This study was a planned subgroup secondary analysis conducted in 10 children's hospitals that included 370 children aged 7 to 17 years with uncomplicated appendicitis enrolled in a prospective, nonrandomized clinical trial between May 1, 2015, and October 31, 2018, with 1-year follow-up comparing nonoperative management with antibiotics vs surgery for uncomplicated appendicitis. Read More

Case Rep Obstet Gynecol 2022 21;2022:1249676. Epub 2022 Apr 21.

Department of Obstetrics and Gynecology, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.

Acute abdomen in pregnancy represents a diagnostic and therapeutic challenge, despite the current advances in modern medicine, since the typical symptoms and altered laboratory parameters mimic normal pregnancy. Acute appendicitis is the most common nonobstetric surgical emergency during pregnancy, with an incidence of 1 per 500-2000 pregnancies. Delayed diagnosis and reluctance to operate on a pregnant woman predispose to adverse maternal and fetal outcomes. Read More

Cir Pediatr 2022 Apr 1;35(2):70-74. Epub 2022 Apr 1.

Gregorio Marañón General University Hospital. Madrid (Spain).

Introduction: Acute appendicitis is the most frequent cause of acute abdomen in children. The objective of this study was to analyze the causes, approach, and results of complications requiring surgery following appendectomy.

Material And Methods: A retrospective study of the appendectomies conducted in three third-level institutions from 2015 to 2019 was carried out. Read More

Ulus Travma Acil Cerrahi Derg 2022 Apr;28(4):418-427

Department of General Surgery, University of Health Sciences, Dışkapı Yıldırım Beyazit Training and Research Hospital, Ankara-Turkey.

Background: This study aims to evaluate the predictive level of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) risk calculator for post-appendectomy complications.

Methods: A total of 292 patients who were hospitalized for general appendectomy were included in the study. The age range of the patients was 18-76 years (mean: 35. Read More

Ulus Travma Acil Cerrahi Derg 2022 May;28(5):703-710

Department of General Surgery, University of Health Sciences, Istanbul Training and Research Hospital, İstanbul-Turkey.

Background: The aim of this study is to examine the cases underwent appendectomy during the COVID-19 pandemic and to discuss the pathology reports of patients.

Methods: During the COVID-19 pandemic, the pathological reports of the appendectomy materials of 588 patients over the age of 15 who applied to the emergency department between January 1, 2020, and June 1, 2021, were examined. A total of 565 patients with a diagnosis of acute (AA), subacute (SA), or perforated appendicitis (PA) were included and divided into three groups according to diagnosis. Read More

Anaesth Crit Care Pain Med 2022 Apr 26;41(4):101091. Epub 2022 Apr 26.

Department of Anaesthesiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China. Electronic address:

Br J Surg 2022 06;109(7):588-594

Department of Gastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background: Mild appendicitis may resolve spontaneously. The use of CT may lead to an overdiagnosis of uncomplicated appendicitis. The aims of this study were to examine whether early imaging results in more patients being diagnosed with acute appendicitis than initial observation, and to study the safety and feasibility of score-based observation compared with imaging in patients with equivocal signs of appendicitis. Read More

S Afr J Surg 2022 Mar;60(1):10-15

Division of Paediatric Surgery, Tygerberg Hospital, Stellenbosch University, South Africa.

Background: The study aimed to compare the outcomes of paediatric laparoscopic appendectomy (LA) with open appendectomy (OA) for complicated appendicitis (CA). All trainees could perform OA without supervision.

Methods: This is a single-centre, retrospective, non-randomised review of children 4-12 years of age, who had either an OA or LA for CA. Read More

BMJ Open 2022 04 21;12(4):e053339. Epub 2022 Apr 21.

Department of Gastrointestinal Surgery, Xiangya Hospital of Central South University, Changsha, China

Objective: Anorectal melanoma (AM) is a rare but aggressive tumour with limited information in the existing literature. This study aimed to assess the effect of surgical treatment for AM and predict the prognosis of affected patients.

Design: A retrospective cohort study. Read More

J Laparoendosc Adv Surg Tech A 2022 Jun 11;32(6):702-712. Epub 2022 Feb 11.

Department of Pediatric Surgery, Faculty of Medicine, Kagawa University, Mikicho, Japan.

There are two approaches to single-incision laparoscopic appendectomy (SILA): intracorporeal (Intra) and extracorporeal (Extra). However, the differences in the efficacy between these procedures remain unclear. Thus, this systematic review and meta-analysis aimed to compare the safety and usefulness of these techniques with those of conventional laparoscopic appendectomy (CLA) in children. Read More

BMC Surg 2022 Apr 8;22(1):134. Epub 2022 Apr 8.

Department of Gastroenterological Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.

Purpose: Acute appendicitis usually requires immediate surgical treatment, but appendectomies were difficult for some patients with severe periappendiceal adhesions. We investigated risk factors of intraoperative adhesions to help surgeons make better treatment plans for appendicitis.

Methods: We retrospectively analyzed 186 cases diagnosed with acute appendicitis and underwent surgery in Shandong Provincial Hospital affiliated to Shandong First Medical University between January 2018 and December 2019. Read More