2,953 results match your criteria Aortitis


Infectious stentitis after treatment of coarctation of the aorta: a case report.

Eur Heart J Case Rep 2020 Jun 3;4(3):1-5. Epub 2020 May 3.

Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

Background: Aortitis is a rare condition that can be caused by inflammatory or infectious aetiologies. The clinical presentation of aortitis includes a heterogeneous range of symptoms and clinical signs.

Case Summary: We present a 53-year-old man whose medical history included presence of a ventricular septal defect, a bicuspid aortic valve, and coarctation of the aorta. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319810PMC

IgG4-related Paravertebral Mass and Peri-aortitis.

Intern Med 2020 Jun 30. Epub 2020 Jun 30.

Department of General Medicine, National Defense Medical College, Japan.

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http://dx.doi.org/10.2169/internalmedicine.4770-20DOI Listing

Giant cell aortitis mimicking aortic intramural hematoma.

Ann Thorac Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Interventional Cardiology and Cardiac Imaging.

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http://dx.doi.org/10.1016/j.athoracsur.2020.05.042DOI Listing

Clinical phenotypes of IgG4-related disease reflect different prognostic outcomes.

Rheumatology (Oxford) 2020 Jun 27. Epub 2020 Jun 27.

Università Vita-Salute San Raffaele, IRCCS San Raffaele Scientific Institute.

Introduction: Four clinical phenotypes of IgG4-related disease (IgG4-RD) have been recently identified by latent class analysis (LCA): pancreato-biliary (group 1); retroperitoneum/aortitis (group 2); head and neck limited (group 3); and Mikulicz/systemic (group 4). The reproducibility of this classification in clinical practice and its relevance for patient management, however, remain unknown.

Methods: The study included 179 patients. Read More

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http://dx.doi.org/10.1093/rheumatology/keaa221DOI Listing
June 2020
4.475 Impact Factor

The comeback of syphilitic aortitis.

Cardiovasc Pathol 2020 May 13;49:107229. Epub 2020 May 13.

Division of Histopathology, University Hospital, Pisa, Italy.

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http://dx.doi.org/10.1016/j.carpath.2020.107229DOI Listing

Curious Case of Retroperitoneal Mass with Elevated Serum IgG3 Levels: An Exception to the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease.

Arthritis Rheumatol 2020 Jun 21. Epub 2020 Jun 21.

Department of Rheumatology, Kaiser Permanente, Los Angeles Medical Center, Los Angeles, California, United States.

We propose a novel case of a retroperitoneal mass and periaortitis with left periureteral involvement in the setting of elevated serum Immunoglobulin G3 (IgG3) that did not fulfill the criteria for Immunoglobulin G4 Related Disease (IgG4-RD) proposed by the newly updated 2019 ACR/EULAR classification criteria. IgG4-RD is an autoimmune fibroinflammatory condition that can affect virtually any organ in the body. Read More

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http://dx.doi.org/10.1002/art.41411DOI Listing

Is There a Brain/Heart Interaction in Rheumatoid Arthritis and Seronegative Spondyloartropathies? A Combined Brain/Heart Magnetic Resonance Imaging Reveals the Answer.

Curr Rheumatol Rep 2020 Jun 19;22(8):39. Epub 2020 Jun 19.

Onassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P.Faliro, Athens, Greece.

Purpose Of Review: To present the interaction between brain/heart and emphasize the role of combined brain/heart magnetic resonance imaging (MRI) in patients with rheumatoid arthritis (RA) and other seronegative spondyloarthropathies (SNA).

Recent Findings: Both traditional cardiovascular disease (CVD) risk factors and intrinsic RA/SNA features contribute to the increased CVD-related morbidity/mortality. CVD in RA usually occurs a decade earlier than age- and sex-matched controls, and RA patients are twice more likely to develop myocardial infarction irrespective of age, history of prior CVD, and traditional CVD risk factors. Read More

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http://dx.doi.org/10.1007/s11926-020-00922-7DOI Listing

Aortitis in the setting of catastrophic antiphospholipid syndrome in a patient with systemic lupus erythematosus.

Lupus 2020 Jun 9:961203320931173. Epub 2020 Jun 9.

Servicio de Medicina Interna, Hospital Universitario Ramón y Cajal, Universidad de Alcalá de Henares, IRYCIS, Madrid, Spain.

Catastrophic antiphospholipid syndrome (CAPS) is a rare condition characterized by multiple thromboses affecting mainly small vessels in a short period of time in patients with antiphospholipid antibodies. A high suspicion index is mandatory in order to initiate rapidly aggressive immunomodulatory therapy to avoid a very poor prognosis. Systemic lupus erythematosus (SLE) is often associated with antiphospholipid syndrome, with a worse outcome when the catastrophic features occur. Read More

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http://dx.doi.org/10.1177/0961203320931173DOI Listing
June 2020
2.197 Impact Factor

Active Aortitis and Dissection in Giant Cell Arteritis While on Tocilizumab Monotherapy.

J Clin Rheumatol 2020 Jun 2. Epub 2020 Jun 2.

University of Wisconsin School of Medicine and Public Health, Madison, WI.

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http://dx.doi.org/10.1097/RHU.0000000000001423DOI Listing

Correction to: Etiology, Diagnosis and Management of Aortitis.

Cardiovasc Intervent Radiol 2020 Jun 3. Epub 2020 Jun 3.

Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.

In the original article, the section "Fact Sheet" was not published. This section should give the reader an overview on the most important take-home messages on aortitis. Please see below the missing section. Read More

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http://dx.doi.org/10.1007/s00270-020-02533-2DOI Listing
June 2020
1.965 Impact Factor

Insidious postoperative Aspergillus niger graft aortitis.

IDCases 2020 16;21:e00823. Epub 2020 May 16.

Città della Salute e della Scienza di Torino, University of Turin, Department of Surgical Sciences, Division of Cardiac Surgery, Italy.

Fungal endocarditis/aortitis is an uncommon yet emerging entity accounting for 2% to 4% of all cases of infective endocarditis and continues to be associated with a poor prognosis. We present the first case of polyethylene-terephthalate (PETE) graft aortitis caused by , a rare fungal agent. Early diagnosis with frequent transoesophageal echocardiography (TEE) and a prompt surgical intervention coupled with optimal antifungal therapy are still the only option to reduce the exceedingly high mortality and morbidity. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256640PMC

Antineoplastic Drug-induced Aortitis: An Unraveled Adverse Effect Using the World Health Organization Pharmacovigilance Database.

J Rheumatol 2020 Jun 1. Epub 2020 Jun 1.

Département de Médecine Interne, Centre de Référence National pour les maladies auto-immunes systémiques rares, Hôpital Cochin, AP-HP; Département de Pharmacologie, Centre Régional de Pharmacovigilance, Hôpital Cochin, AP-HP; Département de Médecine Interne, Centre de Référence National pour les maladies auto-immunes systémiques rares, Hôpital Cochin, AP-HP, and Université Paris Descartes, Paris, France. Address correspondence to Prof. B. Terrier, Department of Internal Medicine, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75679 Paris Cedex 14, France. E-mail:

Aortitis is a rare inflammatory disease ranging from asymptomatic aortic thickening to life-threatening manifestations, especially aortic dissection or stenosis. Aortitis mainly occurs during systemic inflammatory diseases (giant cell arteritis, Takayasu arteritis, IgG4-related disease) and less frequently in patients with syphilis or tuberculosis Aortitis is rarely suspected to be induced by drugs and its causality is hardly assessable. The aim of our study is to identify drugs associated with aortitis occurrence using a data-mining approach. Read More

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http://dx.doi.org/10.3899/jrheum.200023DOI Listing

Giant cell aortitis.

Forensic Sci Med Pathol 2020 May 29. Epub 2020 May 29.

Department of Forensic Medicine, University Hospital Ostrava, CZ-708 52, Ostrava, Czech Republic.

Inflammatory aortic diseases are broadly classified into three categories according to the degree of inflammation: atherosclerosis, atherosclerosis with excessive inflammation, and aortitis/periaortitis. This paper presents a case of a 39-year old man with aneurysmal dilatation of thoracic aorta and aortic valve insufficiency. The aortic wall showed thickening and wrinkled "tree bark" appearance as well as apparent scarring of the intima. Read More

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http://dx.doi.org/10.1007/s12024-020-00242-3DOI Listing

Saprochaete capitata aortitis in an immunocomopetent patient after myocardial revascularization.

Cardiovasc Pathol 2020 Sep - Oct;48:107223. Epub 2020 Apr 28.

Cardiothoracic Department, University Hospital of Udine, Udine, Italy.

Saprochaete species infection is a rare fungal disease reported so far only in immunocompromised patients. We describe the first case of aortitis caused by Saprochaete capitata, presenting as ascending aorta aneurysm, with secondary endophthalmitis in an immunocompetent patient. Infection by Saprochaete capitata is potentially fatal, with a mortality ranging from 50% to 90% of cases. Read More

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http://dx.doi.org/10.1016/j.carpath.2020.107223DOI Listing

Large vessel vasculitis secondary to granulocyte-colony stimulating factor.

Vasa 2020 May 26:1-5. Epub 2020 May 26.

Hospital Universitario Ramon y Cajal, Madrid, Spain.

Aortitis is a rare entity that may cause fever of unknown origin. This entity has a wide various etiologies, which main cause is rheumatologic, but not only. Iatrogenia has also been described, including chemotherapy and supporting treatment (like granulocyte-colony stimulating factor in oncological patients. Read More

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http://dx.doi.org/10.1024/0301-1526/a000872DOI Listing

Tuberculous aortitis as a rare cause of aortobronchial fistula with massive haemoptysis: A case report.

Int J Surg Case Rep 2020 8;70:238-242. Epub 2020 May 8.

Anatomical Pathology Department, Sefako Makgatho Health Sciences University, Dr George Mukhari Tertiary Laboratory, National Health Laboratory Service, Pretoria, South Africa.

Background: Aortobronchial fistula is a rare condition, which is difficult to diagnose. It is fatal if misdiagnosed or not well treated. Massive haemoptysis is usually the first common symptom. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248239PMC

18F-FDG PET/CT Imaging of Vasculitis Complicated With Relapsing Polychondritis.

Clin Nucl Med 2020 Jul;45(7):e327-e328

From the Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Japan.

We present a case of a 38-year-old woman who complained with cough, fever, and back pain with a weight loss. F-FDG PET/CT to search fever origin revealed uptake in the tracheobronchial and the left auricular cartilage and wall of the thoracic aorta. She underwent biopsy of the left auricle and was diagnosed with relapsing polychondritis (RP) complicating vasculitis. Read More

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http://dx.doi.org/10.1097/RLU.0000000000003060DOI Listing

State of the Art Management of Aortic Valve Disease in Ankylosing Spondylitis.

Curr Rheumatol Rep 2020 May 14;22(6):23. Epub 2020 May 14.

Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH, 44195, USA.

Purpose Of Review: Cardiac involvement in patients with ankylosing spondylitis (AS) generally manifests itself as aortic insufficiency, aortitis, disturbance in cardiac conduction, and myocardial dysfunction. We have used a case-based approach to review the current state of the art knowledge regarding the diagnosis and management of aortic valve disease and aortitis in patients with AS.

Recent Findings: The risk for aortic valve disease and aortic valve replacement or repair is significantly higher than in people without AS, and this risk increases with age. Read More

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http://dx.doi.org/10.1007/s11926-020-00898-4DOI Listing

[A Case of Aortitis Caused by a Granulocyte-Colony-Stimulating Factor during Chemotherapy for Pancreatic Cancer].

Gan To Kagaku Ryoho 2020 May;47(5):851-853

Dept. of Surgery, Tohoku University Graduate School of Medicine.

Background: Pegfilgrastim, a long-acting granulocyte-colony-stimulating factor(G-CSF), has been used as prophylaxis for severe hematotoxicity induced by chemotherapy. We report a case of aortitis induced by pegfilgrastim administration during modified FOLFIRINOX(mFOLFIRINOX)chemotherapy for metastatic pancreatic cancer.

Case Report: A 65-year-old woman underwent a distal pancreatectomy for pancreatic tail cancer. Read More

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Etiology, Diagnosis and Management of Aortitis.

Cardiovasc Intervent Radiol 2020 May 10. Epub 2020 May 10.

Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.

Aortitis includes conditions with infectious or non-infectious etiology, characterized by inflammatory changes in one or more layers in aortic wall. Age at onset, geographic predilections, distribution and pattern of involvement in aorta, its branches and pulmonary arteries, and systemic associations provide a clue to etiology. Clinical presentations are often non-specific. Read More

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http://dx.doi.org/10.1007/s00270-020-02486-6DOI Listing
May 2020
1.965 Impact Factor

Complete aortic replacement in aortitis due to aseptic abscess syndrome.

J Vasc Surg Cases Innov Tech 2020 Jun 23;6(2):216-220. Epub 2020 Apr 23.

Department of Vascular Surgery, Rangueil University Hospital, Toulouse, France.

A 36-year-old man was admitted for a tender inflammatory type IV thoracoabdominal aortic aneurysm with multiple aortic dilations. After open repair, he remained frail, but results of all infectious and inflammatory investigations were negative. Hypermetabolic intrasplenic collections were discovered on postoperative computed tomography, and aortitis with aseptic abscess syndrome was strongly suggested. Read More

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http://dx.doi.org/10.1016/j.jvscit.2020.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184059PMC

IgG4-related aortitis/periaortitis and periarteritis: a distinct spectrum of IgG4-related disease.

Arthritis Res Ther 2020 05 4;22(1):103. Epub 2020 May 4.

Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education & National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China.

Background: Large vessels could be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to clarify the clinical features and evaluate the treatment efficacy for IgG4-RD with aortitis/periaortitis and periarteritis (PAO/PA).

Methods: This study prospectively enrolled 587 patients with IgG4-RD with a follow-up time of more than 6 months. Read More

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http://dx.doi.org/10.1186/s13075-020-02197-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197178PMC

Noninfectious aortitis: A case report.

Vascular 2020 May 1:1708538120922107. Epub 2020 May 1.

NYU Langone Health, New York City, NY, USA.

Introduction: Noninfectious aortitis has been increasingly reported worldwide with a growing prevalence in western medicine. Attributed to our increasingly diverse population, western surgeons must be vigilant to promptly differentiate these cases from its more common infectious counterpart in order to ensure subsequent appropriate management of these patients.

Methods: We present a case report of a 71-year-old Indo-Caribbean male who presented with nonspecific abdominal and back pain, found to have aortitis of a noninfectious etiology. Read More

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http://dx.doi.org/10.1177/1708538120922107DOI Listing

Vascular findings on FDG PET/CT.

Br J Radiol 2020 May 6:20200103. Epub 2020 May 6.

Department of Radiology, St Vincent's University Hospital, Dublin, Ireland.

Since its introduction into clinical practice, 2-deoxy-2-[F]flu-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) has become firmly established in the field of oncological imaging, with a growing body of evidence demonstrating its use in infectious and inflammatory vascular pathologies. This pictorial review illustrates the utility of FDG PET/CT as a diagnostic tool in the investigation of vascular disease and highlights some of the more common incidental vascular findings that PET reporters may encounter on standard oncology FDG PET/CTs, including atherosclerosis, large vessel vasculitis, complications of vascular grafts, infectious aortitis and acute aortic syndromes. Read More

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http://dx.doi.org/10.1259/bjr.20200103DOI Listing

Familial HLA-B*52 Vasculitis: Maternal, Atypical Cogan's Syndrome with Takayasu Arteritis-mimicking Aortitis and Filial Takayasu Arteritis.

Intern Med 2020 Apr 23. Epub 2020 Apr 23.

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.

Cogan's syndrome (CS), a rare vasculitis characterized by non-syphilitic, interstitial keratitis and Ménière-like attacks, is classified into "typical" and "atypical" forms, while Takayasu arteritis (TAK) is a rare large-vessel vasculitis associated with HLA-B*52. Very few cases meet both the CS and TAK classification criteria. We herein report a 53-year-old woman diagnosed with atypical CS and aortitis similar to TAK. Read More

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http://dx.doi.org/10.2169/internalmedicine.4067-19DOI Listing

A T2-Weighty Discovery: Aortitis on Cardiac MRI with Histopathologic Correlation.

Methodist Debakey Cardiovasc J 2020 Jan-Mar;16(1):65-67

HOUSTON METHODIST DEBAKEY HEART & VASCULAR CENTER, HOUSTON, TEXAS.

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http://dx.doi.org/10.14797/mdcj-16-1-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137618PMC

Hybrid Repair for Mega-Aortic Syndrome due to Giant Cell Aortitis in a Heart Failure Patient.

Ann Vasc Dis 2020 Mar;13(1):76-80

Department of Cardiovascular Surgery, Mimihara General Hospital, Sakai, Osaka, Japan.

The present report describes a case of mega-aortic syndrome accompanied with severe aortic regurgitation in a 75-year-old man who underwent a two-stage hybrid repair. Intraoperative pathologic findings at the first repair, consisting of Bentall operation and total arch replacement with a Lupiae graft, aided the identification of the giant cell aortitis. Despite complicating hemorrhagic stroke, steroid therapy was initiated and endovascular repair was subsequently completed. Read More

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http://dx.doi.org/10.3400/avd.cr.19-00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140156PMC

Endovascular aortic aneurysm repair to facilitate computed tomography-guided biopsy and aid diagnosis in a case of presumed immunoglobulin G4 aortitis.

ANZ J Surg 2020 Apr 8. Epub 2020 Apr 8.

Department of Vascular Surgery, The Alfred Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/ans.15888DOI Listing

Infectious aortitis mimicking Takayasu disease.

J Med Vasc 2020 Apr 29;45(2):93-95. Epub 2020 Jan 29.

Intensive care unit, Saint André Hospital, 1, rue Jean-Burguet, 33075 Bordeaux cedex, France.

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http://dx.doi.org/10.1016/j.jdmv.2020.01.149DOI Listing

18F-FDG PET/MRI compared with clinical and serological markers for monitoring disease activity in patients with aortitis and chronic periaortitis.

Clin Exp Rheumatol 2020 Mar-Apr;38 Suppl 124(2):99-106. Epub 2020 Apr 2.

Department of Nephrology and Rheumatology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany.

Objectives: We compared the diagnostic value of fully integrated 18F-FDG PET/MRI to that of clinical and serological markers for monitoring disease activity in patients with aortitis/chronic periaortitis (A/CPA) during immunosuppressive therapy.

Methods: Patients positive for A/CPA at the initial and at least 2 consecutive PET/MRI studies were included for retrospective analysis. Imaging (qualitative and quantitative analysis), clinical, and serologic (C-reactive protein, erythrocyte sedimentation rate) assessments were determined at each visit, and their findings compared. Read More

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Aortitis and periaortitis: The puzzling spectrum of inflammatory aortic diseases.

Presse Med 2020 Mar 28;49(1):104018. Epub 2020 Mar 28.

Department of Biomedical, Experimental and Clinical Sciences "Mario Serio" and Meyer Children's Hospital, University of Firenze, Firenze, Italy. Electronic address:

Aortitis and periaortitis are inflammatory diseases of the aorta and its main branches; they differ in the extension of inflammation, which is confined to the aortic wall in aortitis, and spreads to the periaortic space in periaortitis. Aortitis is classified as non-infectious or infectious. Non-infectious aortitis represents a common feature of large-vessel vasculitides but can also be isolated or associated with other rheumatologic conditions. Read More

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http://dx.doi.org/10.1016/j.lpm.2020.104018DOI Listing

IgG4-related pleural disease with aortitis and submandibular glands involvement successfully treated with corticosteroid: case-based review.

Rheumatol Int 2020 Mar 23. Epub 2020 Mar 23.

Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by increased serum IgG4 level, infiltration of lymphocytes and IgG4-positive (IgG4) plasma cells and fibrosis. It can occur in almost all organs, commonly affecting the pancreas, biliary tract, salivary and lacrimal glands and kidneys. However, reports of IgG4-RD accompanied by pathologically confirmed, IgG4-related pleural disease are scarce. Read More

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http://dx.doi.org/10.1007/s00296-020-04555-yDOI Listing

Greater aortic inflammation and calcification in abdominal aortic aneurysmal disease than atherosclerosis: a prospective matched cohort study.

Open Heart 2020 11;7(1):e001141. Epub 2020 Mar 11.

Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UK.

Objective: Using combined positron emission tomography and CT (PET-CT), we measured aortic inflammation and calcification in patients with abdominal aortic aneurysms (AAA), and compared them with matched controls with atherosclerosis.

Methods: We prospectively recruited 63 patients (mean age 76.1±6. Read More

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http://dx.doi.org/10.1136/openhrt-2019-001141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066636PMC

Migratory Aortitis Associated with Granulocyte-colony-stimulating Factor.

Intern Med 2020 Jun 19;59(12):1559-1563. Epub 2020 Mar 19.

Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Japan.

We herein report a case of migratory aortitis after the administration of granulocyte-colony-stimulating factor (G-CSF) to a 65-year-old woman with a history of pancreatic cancer. She was being administered pegfilgrastim and developed aortitis around the aortic arch. Although it resolved within two weeks, she again developed aortitis around the descending aorta, presenting as migratory aortitis, after pegfilgrastim was resumed. Read More

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http://dx.doi.org/10.2169/internalmedicine.4331-19DOI Listing

Pegfilgrastim-associated large-vessel vasculitis developed during adjuvant chemotherapy for breast cancer: A case report and review of the literature.

J Oncol Pharm Pract 2020 Mar 18:1078155220910800. Epub 2020 Mar 18.

Department of Surgery, Yuai-Kai Foundation & Oda Hospital, Kashima, Japan.

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http://dx.doi.org/10.1177/1078155220910800DOI Listing

Aortoenteric fistula secondary to an Inflammatory Abdominal Aortic Aneurysm.

J Radiol Case Rep 2019 Sep 30;13(9):8-27. Epub 2019 Sep 30.

Department of Diagnostic Radiology, Singapore General Hospital, Singapore.

Primary aortoenteric fistulas are rare, with the annual incidence of such fistulas estimated to be 0.007 per million. The most common predisposing conditions for primary aortoenteric fistulas are atherosclerotic abdominal aortic aneurysms or penetrating atherosclerotic ulcers. Read More

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http://dx.doi.org/10.3941/jrcr.v13i9.3746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060010PMC
September 2019

FDG-PET/CT diagnosis of aortitis and pseudoaneurysms.

J Nucl Cardiol 2020 Apr;27(2):362-365

Division of Molecular Imaging and Therapeutics, Department of Radiology, University of Alabama at Birmingham, 619 19th Street South, JT 777, Birmingham, AL, 35249, USA.

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http://dx.doi.org/10.1007/s12350-020-02085-5DOI Listing

Granulocyte colony-stimulating factor- and chemotherapy-induced large-vessel vasculitis: six patient cases and a systematic literature review.

Rheumatol Adv Pract 2020 6;4(1):rkaa004. Epub 2020 Feb 6.

Center for Rheumatology and Clinical Immunology, Division of Medicine, Turku University Hospital, Turku.

Objective: Patients receiving chemotherapy are prone to neutropoenic infections, presenting with non-specific symptoms such as a high fever and elevated inflammatory parameters. Large-vessel vasculitis (LVV) may have a similar clinical presentation and should be included in differential diagnostics. A few published case reports and adverse event reports suggest a causal association between LVV and the use of granulocyte colony-stimulating factor (G-CSF) and chemotherapy. Read More

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http://dx.doi.org/10.1093/rap/rkaa004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046168PMC
February 2020

Cranial and large vessel activity on positron emission tomography scan at diagnosis and 6 months in giant cell arteritis.

Int J Rheum Dis 2020 Apr 26;23(4):582-588. Epub 2020 Feb 26.

Departments of Rheumatology, Nuclear Medicine and Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia.

Aim: Positron emission tomography/computed tomography (PET/CT) can detect cranial and large vessel inflammation in giant cell arteritis (GCA). We aimed to determine the change and significance of vascular activity at diagnosis and 6 months.

Method: Newly diagnosed GCA patients underwent time-of-flight fluorine-18-fluoro-2-deoxyglucose PET/CT from vertex to diaphragm within 72 hours of commencing corticosteroids and were followed for 12 months. Read More

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http://dx.doi.org/10.1111/1756-185X.13805DOI Listing

Generalized Acquired Cutis Laxa Associated with Monoclonal Gammopathy of Dermatological Significance.

Case Rep Dermatol Med 2020 12;2020:7480607. Epub 2020 Feb 12.

Division of Hematology/Oncology and Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Background: Cutis laxa is a rare dermatosis that is inherited or acquired and clinically features loose, wrinkled, and redundant skin with decreased elasticity. This heterogeneous connective tissue disorder may be localized or generalized, with or without internal manifestations. Generalized cutis laxa often has a cephalocaudal progression and is attributed to inflammatory cutaneous eruptions, medications, and infections. Read More

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http://dx.doi.org/10.1155/2020/7480607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037480PMC
February 2020

Multimodal Imaging of Granulomatosis With Polyangiitis Aortitis Complicated by Severe Aortic Regurgitation and Complete Heart Block.

Circ Cardiovasc Imaging 2020 Feb 10;13(2):e009879. Epub 2020 Feb 10.

Department of Cardiology, Imperial College Healthcare NHS Trust, United Kingdom (J.M.T., G.D.C., N.S.P., A.V.).

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http://dx.doi.org/10.1161/CIRCIMAGING.119.009879DOI Listing
February 2020

Comparison of Aortitis Versus Noninflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm Repair.

Arthritis Rheumatol 2020 Jul 5;72(7):1154-1159. Epub 2020 Jun 5.

Hospital of the University of Pennsylvania, Philadelphia.

Objective: Distinguishing aortitis-induced aneurysms from noninflammatory aortic aneurysms is difficult and often incidentally diagnosed on histologic examination after surgical repair. This study was undertaken to examine surgically diagnosed aortitis and identify patient characteristics and imaging findings associated with the disease.

Methods: In this case-control study, cases had newly diagnosed, biopsy-proven noninfectious aortitis after open thoracic aortic aneurysm surgical repair. Read More

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http://dx.doi.org/10.1002/art.41233DOI Listing

Clinically isolated aortitis successfully treated with methotrexate monotherapy.

Rheumatology (Oxford) 2020 Feb 7. Epub 2020 Feb 7.

Unit of Immunology, Rheumatology, Allergy and Rare diseases, IRCCS San Raffaele Hospital.

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http://dx.doi.org/10.1093/rheumatology/keaa008DOI Listing
February 2020

Value of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis of Spondyloarthropathy-Related Aortitis.

J Clin Rheumatol 2020 Feb 5. Epub 2020 Feb 5.

Laboratory of Anatomy, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1097/RHU.0000000000001289DOI Listing
February 2020

Thoracic endovascular repair of a rare case of leaking aortic arch intramural hematoma secondary to Giant cell arteritis.

CVIR Endovasc 2019 Feb 21;2(1). Epub 2019 Feb 21.

Interventional Radiology Department, George Washington University Hospital, Washington, DC, USA.

Background: Traditionally thoracic aortic aneurysms (TAA) secondary to Giant Cell Arteritis (GCA) were treated with resection and open repair. However no prior studies have reported an aortic intramural hematoma (IMH) as a presentation of GCA or outcome of thoracic endovascular aortic repair (TEVAR) in TAA or IMH secondary to GCA.

Case Presentation: A 59 year old female, nonsmoker, non-hypertensive, non-diabetic with a known history of GCA, temporal arteritis on prednisone presented with shortness of breath & chest pain. Read More

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http://dx.doi.org/10.1186/s42155-019-0052-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966361PMC
February 2019

HIV-Associated Aortitis Causing Rapid Development of an Abdominal Aortic Aneurysm.

Ann Vasc Surg 2020 Jul 1;66:669.e11-669.e15. Epub 2020 Feb 1.

Department of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Division of Vascular Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

Vasculitides are rare manifestations of human immunodeficiency virus (HIV) infection. They encompass a wide range of different pathologies, both infectious and noninfectious. We present the case of a 68-year-old female with HIV, being treated with antiretrovirals, who presented with a symptomatic abdominal aortic aneurysm. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.01.088DOI Listing

Interleukin-1 Beta-Mediated Sex Differences in Kawasaki Disease Vasculitis Development and Response to Treatment.

Arterioscler Thromb Vasc Biol 2020 03 30;40(3):802-818. Epub 2020 Jan 30.

From the Division of Infectious Diseases and Immunology, Department of Pediatrics (R.A.P., J.L.M., D.M., B.K., S.C., Y.L., M.N.R., M.A.), Cedars-Sinai Medical Center, Los Angeles, CA.

Objective: Kawasaki disease (KD) is the leading cause of acute vasculitis and acquired heart disease in children in developed countries. Notably, KD is more prevalent in males than females. We previously established a key role for IL (interleukin)-1 signaling in KD pathogenesis, but whether this pathway underlies the sex-based difference in susceptibility is unknown. Read More

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http://dx.doi.org/10.1161/ATVBAHA.119.313863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047651PMC

Ankylosing Spondyloarthritis Resulting Severe Aortic Insufficiency and Aortitis: Exacerbation of Ankylosing Spondyloarthritis and Stenosis of the Main Left Coronary Artery after Mechanical Aortic Valve Implantation with Cardiopulmonary Bypass.

Case Rep Rheumatol 2020 3;2020:9538527. Epub 2020 Jan 3.

Institute of Cardiology of the Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Ankylosing spondyloarthritis (AS) is a chronic inflammatory rheumatic disease, strongly related to human leukocyte antigen (HLA)-B27. Cardiac involvement in AS manifests in 2 to 10% of patients as aortic insufficiency, aortitis, mitral valve fibrosis, or disturbance in the conduction of the heart. In this article, we present a case of a 49-year-old male patient with AS, who was referred to our medical institution for elective aortic valve surgery because of severe aortic regurgitation. Read More

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http://dx.doi.org/10.1155/2020/9538527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964718PMC
January 2020

Syphilitic aortitis: still a current common cause of aneurysm of the tubular portion of ascending aorta.

Cardiovasc Pathol 2020 May - Jun;46:107175. Epub 2019 Oct 28.

Department of Cardiac Surgery, Baylor University Medical Center, Dallas, TX, USA.

Aortic syphilis today is infrequently diagnosed clinically. Described herein are findings in 5 women who had resection of a fusiform aneurysm of the tubular portion of ascending aorta, and examination of the wall of the aneurysm disclosed classic features of aortic syphilis. The 5 patients were among 36 who had ascending aortic operations at Baylor University Medical Center in Dallas in 2018 and early 2019. Read More

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http://dx.doi.org/10.1016/j.carpath.2019.107175DOI Listing