3,097 results match your criteria Aortitis


aortitis in a patient with HIV.

IDCases 2021 23;25:e01169. Epub 2021 May 23.

Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.

A 36-year-old man with well controlled HIV developed aortitis. To prevent aortic rupture, emergent surgical resection and neo-aortoiliac replacement with his left femoral vein was conducted. After surgical intervention, he was successfully treated with intravenous ertapenem for 6 weeks followed by oral amoxicillin for 3 months. Read More

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Recurrent Stent Thrombosis Secondary to Immunoglobulin G4-Related Disease.

Can J Cardiol 2021 Jun 3. Epub 2021 Jun 3.

Department of Cardiology, National University Heart Centre Singapore, Singapore.

Immunoglobulin G4-related disease (IgG4-RD) is an insidiously progressive multi-organ disease. However, lack of familiarity with IgG4-RD results in patients often being undiagnosed and under treated. IgG4-RD can affect any organ, and manifests as aortitis within the cardiovascular system. Read More

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Imaging features of mycotic aortic aneurysms.

Quant Imaging Med Surg 2021 Jun;11(6):2861-2878

Department of Cardiovascular Surgery, Beijing Aortic Disease Centre, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Engineering Research Centre for Vascular Prostheses, Beijing, China.

Infectious aortitis (IA) is a rare and life-threatening cardiovascular disease. Early diagnosis and timely intervention are crucial for reducing mortality associated with mycotic aortic aneurysms (MAAs); however, early diagnosis is challenging due to the nonspecific symptoms. Some cases are diagnosed at an advanced stage or after developing complications, such as rupture or aortic fistula. Read More

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Impending Aortic Rupture in a Patient with Syphilitic Aortitis.

Vasc Health Risk Manag 2021 25;17:255-258. Epub 2021 May 25.

Department of Cardiology, Institute of Cardiovascular Diseases, Timisoara, Romania.

We report the case of a 48-year-old man, admitted for atrial fibrillation with rapid heart rate and intense chest pain. A quick evaluation revealed a giant aortic aneurysm with severe aortic regurgitation and pericardial fluid without a trace of aortic dissection. Because of high suspicion of aortic rupture, an emergency surgery was planned, and a Bentall procedure was performed. Read More

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Atypical presentation of Takayasu aortitis and myocarditis contributing to sudden death in a young Canadian First Nations adult.

Cardiovasc Pathol 2021 May 23:107347. Epub 2021 May 23.

Department of Pathology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

This is a rare presentation of Takayasu arteritis in a 30-year-old Canadian First Nations woman with cardiac and aortic root-predominant disease, which manifested in complete heart block. She had a past medical history significant for substance misuse. At presentation, cardiac magnetic resonance imaging identified diffuse thickening of the left atrium and ventricular outflow tract with left ventricular cavity dilation and preserved systolic function. Read More

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Clinically isolated aortitis presenting as inferior ST-elevation myocardial infarction due to an unruptured sinus of Valsalva aneurysm: a rare and forgotten cause of acute coronary syndrome in a young patient with no evidence of systemic vasculitis.

BMJ Case Rep 2021 May 24;14(5). Epub 2021 May 24.

Section of Cardiothoracic Surgery, Aga Khan University Hospital, Karachi, Pakistan.

A 21-year-old man presented with chest pain, diaphoresis and dyspnoea. Electrocardiogram (ECG) showed inferior ST-elevation myocardial infarction. Troponin I was positive. Read More

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MicroRNA-223 Regulates the Development of Cardiovascular Lesions in LCWE-Induced Murine Kawasaki Disease Vasculitis by Repressing the NLRP3 Inflammasome.

Front Pediatr 2021 7;9:662953. Epub 2021 May 7.

Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Kawasaki disease (KD), an acute febrile childhood illness and systemic vasculitis of unknown etiology, is the leading cause of acquired heart disease among children. Experimental data from murine models of KD vasculitis and transcriptomics data generated from whole blood of KD patients indicate the involvement of the NLRP3 inflammasome and interleukin-1 (IL-1) signaling in KD pathogenesis. MicroRNA-223 (miR-223) is a negative regulator of NLRP3 activity and IL-1β production, and its expression has been reported to be upregulated during acute human KD; however, the specific role of miR-223 during KD vasculitis remains unknown. Read More

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The forgotten and silent enemy of the cardiovascular system: a rare case of aortitis.

Enferm Infecc Microbiol Clin (Engl Ed) 2021 May 13. Epub 2021 May 13.

Servicio de Cardiología, Hospital Universitario Álvaro Cunqueiro, Vigo, España.

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Acute Hypoxia in a 78-year-old Female with Bacteremia and a History of Syphilis.

Am J Med 2021 May 11. Epub 2021 May 11.

Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, United States; Section of Cardiovascular Research, Heart, Vascular and Thoracic Department, Cleveland Clinic Akron Genera, Akron, Ohio, United States.

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[Probable Immunoglobulin G4 (IgG4)-related Periaortitis Requiring Differentiation from Mediastinal Tumor].

Kyobu Geka 2021 Feb;74(2):108-111

Department of Thoracic Surgery, Sapporo Medical University, Sapporo, Japan.

A 42-year-old man with a history of suspected of Behcet's disease underwent oral steroid treatment. During follow-up, chest X-ray revealed an abnormal shadow of the mediastinum. Chest computed tomography(CT) showed a circumferential tumor around the descending thoracic aorta. Read More

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February 2021

Diagnostic value of [18F]FDG-PET/CT for treatment monitoring in large vessel vasculitis: a systematic review and meta-analysis.

Eur J Nucl Med Mol Imaging 2021 May 3. Epub 2021 May 3.

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Purpose: Monitoring disease activity in patients with large vessel vasculitis (LVV) can be challenging. [18F]FDG-PET/CT is increasingly used to evaluate treatment response in LVV. In this systematic review and meta-analysis, we aimed to summarize the current evidence on the value of [18F]FDG-PET/CT for treatment monitoring in LVV. Read More

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Infected Aortitis, Psoas Muscle Abscess and Infectious Spondylitis.

J Acute Med 2021 Mar;11(1):32-34

Ditmanson Medical Foundation Chia-Yi Christian Hospital Department of Emergency Medicine Chiayi Taiwan.

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Clostridial Mycotic Aneurysm Leading to Emphysematous Aortitis.

Cureus 2021 Mar 27;13(3):e14136. Epub 2021 Mar 27.

Radiology, Rutgers University, Newark, USA.

Mycotic aneurysms account for less than 5% of all aneurysms of the aorta, with most cases linked to infection with either or species. Emphysematous aortitis is a rare consequence of mycotic aneurysms and is associated with high morbidity and mortality. It typically occurs from infection superimposed on already damaged endothelium, which is commonly seen in conditions such as atherosclerosis. Read More

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Cardiovascular complications of bacteraemia.

BMJ Case Rep 2021 Apr 7;14(4). Epub 2021 Apr 7.

Heart Center, department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands

The incidence of bacteraemia has risen due to a worldwide increase in immunocompromised patients and antibiotic resistance. We describe three patients who experienced severe, including cardiovascular, complications of pneumococcal bacteraemia. Cardiovascular complications related to pneumococci may run a fulminant course. Read More

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Syphilitic Aortic Aneurysm: A Rare Entity in the Era of Antibiotics.

Cureus 2021 Mar 1;13(3):e13647. Epub 2021 Mar 1.

Medicine, MedStar Union Memorial Hospital, Baltimore, USA.

A thoracic aortic aneurysm is a rare entity of tertiary syphilis in the era of antibiotics. The diagnosis of the aortic aneurysm due to tertiary syphilis may be challenging due to deceptive clinical presentation and rarity of the disease in the western world. We report the case of a 59-year-old man, who presents with worsening shortness of breath and was found to have a large ascending aortic aneurysm on computed tomography angiogram (CTA) of the chest. Read More

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Aortic Pathology During COVID - 19 Pandemics. Clinical Reports in Literature and Open Questions on the two Co-Occurring Conditions.

Ann Vasc Surg 2021 Apr 3. Epub 2021 Apr 3.

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

Background: Cardiovascular involvement in SARS-CoV-2 infection has emerged as one of viral major clinical features during actual pandemic; limb arterial ischemic events, venous thrombosis, acute myocardial infection and stroke have occurred in patients. Acute aortic conditions have also been described, followed by interesting observations on cases, hypothesis, raised since the emergence of the pandemics.

Methods: a review of cases in literature of aortic pathology in patients with clinically suspected/microbiologically confirmed COVID-19 infection has been carried out to analyze anagraphic data, clinical presentation, treatment options and outcome. Read More

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Echocardiographic clues in diagnosis of Takayasu arteritis in a child with SARS-CoV-2 related Multisystem Inflammatory Syndrome.

CASE (Phila) 2021 Mar 27. Epub 2021 Mar 27.

Section of Pediatric Cardiology. Baylor College of Medicine and Texas Children's Hospital, Houston, TX 77030.

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Unexpected giant cell aortitis in a young patient.

Int J Surg Case Rep 2021 Apr 11;81:105741. Epub 2021 Mar 11.

Department of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, Queensland, Australia.

Introduction And Importance: Giant cell aortitis is a rare cause of ascending aortic aneurysm disease. Patients presenting with aneurysms caused by giant cell aortitis are at high risk of devastating complications.

Case Presentation: A 35-year-old female with an ascending aortic aneurysm, underwent an aortic root and ascending aorta replacement and subsequently was found to have giant cell aortitis on histopathology. Read More

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Takayasu´s Disease Presenting as a Hypertensive Urgency.

Circ Cardiovasc Imaging 2021 Apr 2;14(4):e011827. Epub 2021 Apr 2.

Cardiovascular Institute (C.N.P.-G., N.R.-L., C.R., D.V., C.F., I.V.), Hospital Clínico San Carlos, Madrid, Spain.

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More difficult still: Treating severe rapidly progressive glomerulonephritis in the context of COVID-19 pneumonia.

Nefrologia (Engl Ed) 2021 Jan 28. Epub 2021 Jan 28.

Servicio de Nefrología, Hospital Universitario Infanta Leonor, Madrid, España.

We present the case of a male patient with severe SARS-CoV-2 pneumonia, with simultaneous onset of p-ANCA positive rapidly progressive glomerulonephritis. We discuss the different therapeutic possibilities, emphasising the appropriateness of their administration according to the time in the course of the infection. Read More

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January 2021

Lessons of the month: ANCA-associated vasculitis - granulomatosis with polyangiitis: 'the great mimic'.

Clin Med (Lond) 2021 03;21(2):e231-e233

North Bristol NHS Trust, Bristol, UK and University of Bristol, Bristol, UK.

We describe the case of a 61-year-old woman who presented with progressive respiratory symptoms and imaging demonstrating multiple opacities in the right lung with hilar and mediastinal lymphadenopathy suggestive of multifocal adenocarcinoma. Subsequent biopsies were consistent with focal changes of organising pneumonia (OP) and no evidence of malignancy. She was treated with steroids for cryptogenic OP with limited response. Read More

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Small vessel occlusion and syphilis in patients with first-ever ischemic stroke.

Arq Neuropsiquiatr 2021 02;79(2):103-106

Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Neurologia, Curitiba PR, Brazil.

Background: Syphilis is an endemic disease, particularly in low- and middle-income countries, with vascular involvement in large vessels (aortitis), but no clear relationship with stroke patients, except for those who presented with meningovascular neurosyphilis.

Objective: To investigate the relationship between a positive history of syphilis determined by serological testing and ischemic stroke etiology, particularly small vessel disease (SVD).

Methods: In total, 269 first-ever ischemic stroke patients admitted to the stroke unit were tested for syphilis. Read More

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February 2021

Syphilitic Aortitis Causing Severe Bilateral Coronary Ostial Stenosis.

JACC Cardiovasc Interv 2021 Apr 17;14(7):e65-e67. Epub 2021 Mar 17.

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, People's Republic of China. Electronic address:

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Steroid-sparing effect of anakinra in giant-cell arteritis: a case series with clinical, biological and iconographic long-term assessments.

Rheumatology (Oxford) 2021 Mar 20. Epub 2021 Mar 20.

Service de Médecine Interne, CHU de Caen Normandie, 14000 Caen, France.

Objectives: The treatment of giant cell arteritis (GCA) relies on corticosteroids but is burdened by a high rate of relapses and adverse effects. Anti-interleukin-6 treatments show a clear benefit with a significant steroid-sparing effect, but late relapses occur after treatment discontinuation. In addition to interleukin-6, interleukin-1 also appears to play a significant role in GCA pathophysiology. Read More

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Favorable Conservative Management of a Rare Primary Aortitis Secondary to Listeria Monocytogenes: Case Report and Review of the Literature.

Vasc Endovascular Surg 2021 Mar 19:15385744211004056. Epub 2021 Mar 19.

Department of Surgery, Section of Vascular Surgery and Endovascular Therapy, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, Mexico.

Primary aortitis (PA) secondary to Listeria monocytogenes is extremely rare with only a few cases reported in the literature. Presently, there is no consensus concerning the best treatment when no complications are found in the thoracic computed tomography (CT) imaging. This report illustrates the clinical presentation and favorable clinical course of a rare case of PA secondary to in an 82-year-old diabetic woman, successfully treated with conservative management with 18 months of follow up. Read More

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Tuberculosis and the Heart.

J Am Heart Assoc 2021 Apr 18;10(7):e019435. Epub 2021 Mar 18.

Division of Cardiology Kingston Health Science CenterQueen's University Kingston Canada.

Acquired tuberculosis continues to be a challenge worldwide. Although tuberculosis has been considered a global public health emergency, it remains poorly controlled in many countries. Despite being primarily a pulmonary disease, tuberculosis could involve the heart. Read More

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Aortitis in COVID-19.

IDCases 2021 10;24:e01063. Epub 2021 Mar 10.

Department of Hospital Medicine, Guthrie Robert Packer Hospital, Sayre, PA, USA.

Corona Virus Disease of 2019 (COVID-19) pandemic has affected more than 67.9 million individuals world-wide and led to more than 15.5 million Deaths. Read More

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The Immunopathology of Giant Cell Arteritis Across Disease Spectra.

Front Immunol 2021 25;12:623716. Epub 2021 Feb 25.

Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

Giant cell arteritis (GCA) is a granulomatous systemic vasculitis of large- and medium-sized arteries that affects the elderly. In recent years, advances in diagnostic imaging have revealed a greater degree of large vessel involvement than previously recognized, distinguishing classical cranial- from large vessel (LV)- GCA. GCA often co-occurs with the poorly understood inflammatory arthritis/bursitis condition polymyalgia rheumatica (PMR) and has overlapping features with other non-infectious granulomatous vasculitides that affect the aorta, namely Takayasu Arteritis (TAK) and the more recently described clinically isolated aortitis (CIA). Read More

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February 2021

Recurrent Granulocyte Colony-Stimulating Factor-Induced Aortitis After Pegfilgrastim Administration.

Circ Rep 2020 Oct 27;2(12):764-765. Epub 2020 Oct 27.

Division of Cardiology, Shimane University Faculty of Medicine Izumo Japan.

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October 2020