3,233 results match your criteria Aortitis


Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy.

Ulster Med J 2022 May 15;91(2):92-94. Epub 2022 Jun 15.

Vascular Surgical Unit, Royal Victoria Hospital, Belfast, UK.

We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of intravesical BCG treatment, haematological seeding causing tuberculous aortitis and mycotic pseudo-aneurysm formation of the infra-renal aorta. It also illustrates successful treatment with emergency open surgery, local debridement of mycotic pseudoaneurysm, in-situ surgical reconstruction using a custom bovine-wrap interposition graft to create a neo-aorta and multi-agent anti-tuberculous chemotherapy. Read More

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Mycotic pseudoaneurysm and aortitis caused by Candida sake.

Rev Esp Cardiol (Engl Ed) 2022 Jun 2. Epub 2022 Jun 2.

Departamento de Microbiología y Parasitología Clínica, Hospital Universitario de Basurto, Bilbao, Vizcaya, Spain; Instituto de Investigación Sanitaria Biocruces, Barakaldo, Vizcaya, Spain.

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Catastrophic Perforation in Streptococcus Pneumoniae Aortitis: Complications of Infective Endocarditis in the Current Antimicrobial Era.

J Community Hosp Intern Med Perspect 2022 31;12(1):48-53. Epub 2022 Jan 31.

Department of Internal Medicine, SSM St. Mary's Hospital - St. Louis, St. Louis, MO 63117, USA.

Infectious aortitis is an uncommon but life-threatening cause of aortitis. Given the lack of specific symptoms, establishing the diagnosis is often a challenge. When it is associated with an endovascular infection, such as infective endocarditis, blood cultures may be diagnostic although often limited by low positive predictive value. Read More

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January 2022

Anterior spinal artery syndrome due to aortitis.

JTCVS Tech 2022 Jun 22;13:7-8. Epub 2022 Feb 22.

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital Essen, Essen, Germany.

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Recent advances in the diagnosis and therapy of large vessel vasculitis.

Pol Arch Intern Med 2022 Jun 6. Epub 2022 Jun 6.

Large vessel vasculitis (LVV), including Takayasu arteritis (TAK) and giant cell arteritis (GCA), causes granulomatous vascular inflammation mainly in large vessels, and is the most common primary vasculitis in adults. Vascular inflammation may evoke many clinical features including vision impairment, stroke, limb ischemia, and aortic aneurysms. The best way to diagnose LVV is to combine medical history, physical examination, various laboratory tests, and imaging modalities. Read More

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High risk and low prevalence diseases: Giant cell arteritis.

Am J Emerg Med 2022 May 31;58:135-140. Epub 2022 May 31.

SAUSHEC, Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA. Electronic address:

Introduction: Giant cell arteritis (GCA) is a serious condition that carries with it a high rate of morbidity.

Objective: This review highlights the pearls and pitfalls of GCA in adult patients, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.

Discussion: GCA is an immune-mediated vasculitis of medium-sized vessels that primarily affects those over the age of 50 years. Read More

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Neuropathology of Pediatric SARS-CoV-2 Infection in the Forensic Setting: Novel Application of Imaging in Analysis of Brain Microvasculature.

Front Neurol 2022 24;13:894565. Epub 2022 May 24.

Office of Chief Medical Examiner, New York, NY, United States.

Two years into the COVID-19 pandemic, there are few published accounts of postmortem SARS-CoV-2 pathology in children. We report 8 such cases (4 infants aged 7-36 weeks, 4 children aged 5-15 years). Four underwent magnetic resonance neuroimaging, to assist in identification of subtle lesions related to vascular compromise. Read More

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bacteremia and its implications: A case report.

IDCases 2022 20;29:e01516. Epub 2022 May 20.

Department of Infectious Disease, University Medical Center, 1800 W Charleston Blvd, Las Vegas, NV 89102, United States.

Background: The species is a gram positive, anaerobic, rod-shaped microbe that is known to produce many toxins. Most infections by the species involve , , and . However, other types of species are also clinically relevant, such as and . Read More

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The Role of Ultrasound and FDG-PET/CT to Detect Extracranial Artery Involvement in Patients with Suspected Large Vessel Vasculitis.

Mod Rheumatol 2022 Jun 4. Epub 2022 Jun 4.

Department of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Objective: To assess the accuracy of ultrasound (US) versus FDG-PET/CT to identify extracranial involvement in suspected large vessel vasculitis (LVV) patients.

Methods: Retrospective observational study of patients referred to our US fast track clinic with suspected LVV. All patients underwent US exam within 24 hours per protocol. Read More

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[Thoracic manifestations of Behcet's disease].

Rev Mal Respir 2022 May 31. Epub 2022 May 31.

Sorbonne Université, Pitié-Salpêtrière University Hospital, Paris, France; Department of Internal Medicine and Clinical Immunology, Paris, France; Centre de référence des maladies auto-immunes systémiques rares, centre de référence des maladies auto-inflammatoires et de l'amylose inflammatoire, AP-HP, 75013 Paris, France; Institut national de la santé et de la recherche médicale, Paris, France; Inserm, UMR_S 959, 75013, Paris, France; RHU IMAP, CNRS, FRE3632, 75005 Paris, France. Electronic address:

Behcet's disease (BD) is a multisystemic vasculitis involving arteries and veins of all sizes. While joint and dermatological manifestations are the most common features of BD and are associated with a good prognosis; vascular involvement, remains the principal cause of death. Arterial manifestations occur in 5-10% of cases and manifest as occlusion/thrombosis or aneurysms. Read More

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Aortic Involvement in Disseminated Tuberculosis - Challenges Beyond the Diagnosis.

Infect Drug Resist 2022 23;15:2633-2638. Epub 2022 May 23.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People's Republic of China.

Tuberculous aortitis (TA) is a rare disease with a high mortality rate. Aortic pseudoaneurysm is the most common vascular pattern of TA, and isolated arterial wall thickening and arterial stenosis can also be seen in TA. We report two cases of disseminated tuberculosis involving the aorta with clinical improvement after treatment. Read More

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Ascending aortic aneurysm associated with lymphoplasmacytic thoracic aortitis mimics acute type A intramural hematoma - case report.

Rozhl Chir 2022 ;101(4):184-188

Introduction: Lymphoplasmacytic thoracic aortitis is still underrecognized cause of thoracic aortic aneurysm.

Case Report: We herein report a case of symptomatic inflammatory ascending aortic aneurysm and pericarditis diagnosed on CT scan as acute type A intramural hematoma. Patient underwent emergency supracoronary ascending aorta replacement with a prosthetic graft. Read More

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[A Case of Aortitis Caused by Pegfilgrastim Use during Neoadjuvant Chemotherapy for Treating Breast Cancer].

Gan To Kagaku Ryoho 2022 May;49(5):573-576

Division of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine.

Granulocyte colony-stimulating factor(G-CSF)is useful for preventing febrile neutropenia induced by chemotherapy. Recently, some cases of aortitis have been reported following administration of G-CSF. Here, we present a case of aortitis induced by pegfilgrastim(peg-G)use during neoadjuvant chemotherapy for treating breast cancer. Read More

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Syphilitic Aortitis.

N Engl J Med 2022 05 14;386(20):e55. Epub 2022 May 14.

Memorial Regional Hospital, Hollywood, FL

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Emphysematous Aortitis.

N Engl J Med 2022 05;386(19):1833

University of Maryland Medical Center, Baltimore, MD

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Regression of IgG4-related coronary arteritis and aortitis with immunosuppressive therapy.

Eur Heart J Case Rep 2022 May 8;6(5):ytac156. Epub 2022 Apr 8.

Department of Medicine, The University of Hong Kong, Hong Kong, China.

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Giant cell arteritis-related stroke in a large inception cohort: A comparative study.

Semin Arthritis Rheum 2022 Apr 28;55:152020. Epub 2022 Apr 28.

Internal Medicine Department, University Hospital of Limoges, France. Electronic address:

Objective: Stroke caused by giant cell arteritis (GCA) is a rare but devastating condition and early recognition is of critical importance. The features of GCA-related stroke were compared with those of GCA without stroke and atherosclerosis-related or embolic stroke with the aim of more readily diagnosing GCA.

Methods: The study group consisted of 19 patients who experienced GCA-related strokes within an inception cohort (1982-2021) of GCA from the internal medicine department, and the control groups each consisted of 541 GCA patients without a stroke and 40 consecutive patients > 50 years of age with usual first ever stroke from the neurology department of a French university hospital. Read More

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Magnetic resonance imaging-based diagnosis of aortitis preceding development of a thoracic aneurysm in a patient with giant cell arteritis: a case report.

Eur Heart J Case Rep 2022 Apr 12;6(4):ytac152. Epub 2022 Apr 12.

Department of Radiology and Neuroradiology, University Medical Center Schleswig Holstein, Campus Kiel, Kiel, Germany.

Background: Inflammatory manifestation in the aortic arch can be a complication of giant cell arteritis (GCA), potentially requiring surgical therapy in the case of aneurysmatic dilatation.

Case Summary: We report the case of a 73-year-old female patient with GCA in whom a typical appearance of arteritis was visualized on magnetic resonance imaging of the superficial temporal arteries. Additionally, ectasia (4. Read More

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Multimodality Evaluation of Aortic Insufficiency and Aortitis in Rheumatologic Diseases.

Front Cardiovasc Med 2022 12;9:874242. Epub 2022 Apr 12.

Division of Cardiology, Johns Hopkins University, Baltimore, MD, United States.

Aortic insufficiency is commonly observed in rheumatologic diseases such as ankylosing spondylitis, systemic lupus erythematosus, antiphospholipid syndrome, Behçet's disease, granulomatosis with polyangiitis, and Takayasu arteritis. Aortic insufficiency with an underlying rheumatologic disease may be caused by a primary valve pathology (leaflet destruction, prolapse or restriction), annular dilatation due to associated aortitis or a combination of both. Early recognition of characteristic valve and aorta morphology on cardiac imaging has both diagnostic and prognostic importance. Read More

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Prospects of conservative treatment for associated aortitis.

J Vasc Surg Cases Innov Tech 2022 Jun 1;8(2):227-231. Epub 2022 Apr 1.

Department of Surgery, Ordensklinikum Linz, Linz, Austria.

bacteremia is a rare (72 cases reported) aneurysm-inducing disease that has resulted in a 6-month mortality of 100% when treated conservatively. We report the case of a patient who was completely symptom free at 6 months of follow-up but who ultimately died at 8.9 months after aortic rupture. Read More

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Acute Limb Ischemia in Cogan Syndrome.

Am J Case Rep 2022 Apr 30;23:e935929. Epub 2022 Apr 30.

Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL, USA.

BACKGROUND Cogan syndrome is a rare autoimmune disorder associated most frequently with ocular, vestibular, and auditory involvement from presumed small vessel vasculitis. Cogan syndrome, in a significant proportion of patients, can progress to systemic symptoms, including gastrointestinal, neurologic, and musculoskeletal manifestations. Large-vessel involvement has also been described in some cases (eg, aortitis), but acute limb ischemia in the setting of this illness has been infrequently reported. Read More

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Invasive non-typhoidal infection complicated by metastatic infections: Report of three cases.

IDCases 2022 8;28:e01498. Epub 2022 Apr 8.

Department of Medicine, Infectious Disease Unit, Brugmann University Hospital, Brussels, Belgium.

Non-typhoidal (NTS) disease is usually a self-limiting infection presenting with digestive symptoms. However, disseminated presentation with involvement of secondary infectious sites is observed. We report diagnostic specificities and challenges related to the management of three patients with invasive NTS (iNTS) and secondary infectious locations. Read More

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[A Huge Aortic Root Aneurysm Nineteen Years After Aortic Valve Replacement:Report of a Case].

Kyobu Geka 2022 May;75(5):396-399

Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.

We report a case of huge aortic root aneurysm 19 years after aortic valve replacement. A 58-year-old woman was referred to us for aortic root dilatation. She underwent aortic valve replacement with mechanical valve due to severe aortic regurgitation of tricuspid aortic valve 19 years ago. Read More

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A review on the deeper understanding of inflammation and infection of the thoracic aorta.

Vascular 2022 Apr 25:17085381211060928. Epub 2022 Apr 25.

Department of Cardiothoracic Surgery, RinggoldID:156669Liverpool Heart and Chest Hospital, Chester, UK.

Objective: To review the current literature regarding infection and inflammation of the thoracic aorta and to summarise its aetiologies, pathogenesis and clinical presentation. Additionally, the authors sought to compare diagnostic methods and to analyse the different management options.

Method: A comprehensive electronic search using PubMed, MEDLINE, Scopus and Google Scholar was conducted to find relevant journal articles with key search terms including: 'aortitis', 'thoracic aortic infection' and 'surgical management of infected thoracic aortic aneurysms'. Read More

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ANCA-associated vasculitis and IgG4-related disease overlap syndrome: a case report and literature review.

Immunol Res 2022 Apr 21. Epub 2022 Apr 21.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col. Sección XVI, Tlalpan, Mexico City, Mexico, 14080.

Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides are infrequent autoimmune diseases characterized by inflammation of the walls of small vessels leading to tissue and endothelial damage. On the other hand, IgG4-related disease is a fibroinflammatory disease characterized histologically by lymphoplasmacytic infiltrates with IgG4+ plasma cells, storiform fibrosis, and obliterative phlebitis that may affect nearly every organ of the body. There are similarities in clinical, serological, radiological, and histopathological features between both diseases, and hence, they usually mimic each other complicating the differential diagnosis. Read More

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Immunoglobulin G4-related coronary periarteritis: a systematic literature review with a case series.

Clin Rheumatol 2022 Apr 20. Epub 2022 Apr 20.

Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan.

We aimed to assess the clinical and radiological characteristics of immunoglobulin G4-related coronary periarteritis through a systematic literature review and from our case series. In the systematic literature review, we assessed English language manuscripts on immunoglobulin G4-related coronary periarteritis cases. Additionally, we identified patients with immunoglobulin G4-related coronary periarteritis at St. Read More

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Infectious Aortitis: Case Report and Literature Review.

Cureus 2022 Mar 15;14(3):e23198. Epub 2022 Mar 15.

Internal Medicine/Geriatrics, McLaren Health Care, Michigan State University (MSU), Flint, USA.

Aortitis is the inflammation of the aorta secondary to either infectious or non-infectious etiologies. Infectious aortitis is a rare but potentially life-threatening condition. It is more common among older patients with preexisting pathology. Read More

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Global Transcriptomic Profiling Identifies Differential Gene Expression Signatures Between Inflammatory and Noninflammatory Aortic Aneurysms.

Arthritis Rheumatol 2022 Apr 11. Epub 2022 Apr 11.

Mayo Clinic, Rochester, Minnesota.

Objective: To identify hallmark genes and biomolecular processes in aortitis using high-throughput gene expression profiling, and to provide a range of potentially new drug targets (genes) and therapeutics from a pharmacogenomic network analysis.

Methods: Bulk RNA sequencing was performed on surgically resected ascending aortic tissues from inflammatory aneurysms (giant cell arteritis [GCA] with or without polymyalgia rheumatica, n = 8; clinically isolated aortitis [CIA], n = 17) and noninflammatory aneurysms (n = 25) undergoing surgical aortic repair. Differentially expressed genes (DEGs) between the 2 patient groups were identified while controlling for clinical covariates. Read More

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Aortitis and aortic dissection after administration of pegfilgrastim during adjuvant chemotherapy for early breast cancer.

Int Cancer Conf J 2022 Apr 23;11(2):138-141. Epub 2022 Feb 23.

Department of Breast Surgery, Osaka Red Cross Hospital, 5-30 Fudegasaki-cho, Tennoji-ku, Osaka, 543-8555 Japan.

A 70 year-old woman on adjuvant chemotherapy for breast cancer developed acute aortitis after receiving pegfilgrastim. 12 days after pegfilgrastim administration, she presented to our hospital with fever and shoulder pain. White blood cell count and C-reactive protein were elevated. Read More

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