2,783 results match your criteria Aortitis


Ruptured Syphilitic Aneurysm: A Cause of Sudden Death in a Man with Human Immunodeficiency Coinfection.

J Forensic Sci 2019 Mar 20. Epub 2019 Mar 20.

Department of Legal Medicine, St. Marianna University School of Medicine, Kanagawa, 216-8511, Japan.

Syphilis, a sexually transmitted infection caused by the bacterium Treponema palladium, is experiencing a worldwide resurgence. The risk of syphilis infection is particularly high in men who have sex with men (MSM), especially those who are human immunodeficiency virus (HIV)-positive. Untreated syphilis can lead to rare but severe late-stage complications, including syphilitic aortitis. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1556-4029.14
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http://dx.doi.org/10.1111/1556-4029.14046DOI Listing
March 2019
1 Read

Clinical course of abdominal aortic aneurysms in Behçet disease: a retrospective analysis.

Rheumatol Int 2019 Mar 19. Epub 2019 Mar 19.

Division of Rheumatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Fatih, 34093, Istanbul, Turkey.

Arterial aneurysms are rare manifestations of Behçet Disease (BD) with high morbidity and mortality. This study aimed to investigate the clinical course of BD patients with abdominal aortic aneurysms (AAA). We retrospectively searched charts of BD patients, followed up between 1988 and 2011, to identify those with AAA with at least 6-month clinical and radiological follow-up data. Read More

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http://dx.doi.org/10.1007/s00296-019-04283-yDOI Listing

Granulocyte colony-stimulating factor-associated aortitis in the Japanese Adverse Drug Event Report database.

Cytokine 2019 Mar 12;119:47-51. Epub 2019 Mar 12.

The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:

Background: Granulocyte colony-stimulating factor (G-CSF) is the standard-of-care therapy for chemotherapy-associated neutropenia in patients with malignancies. Recent case reports have implied that G-CSF treatment may be associated with the development of aortitis, but the precise nature of the relationship is unclear. We investigated the association between G-CSF and risk for aortitis in patients with various malignancies. Read More

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http://dx.doi.org/10.1016/j.cyto.2019.02.013DOI Listing
March 2019
2 Reads

A case of Hughes-Stovin syndrome (incomplete Behçet's disease) with extensive arterial involvement : Unmasking the true face of a rare syndrome.

Z Rheumatol 2019 Mar 14. Epub 2019 Mar 14.

Faculty of Behavioral, Management and Social Sciences, Department Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.

Hughes-Stovin syndrome (HSS), characterized by the combination of multiple pulmonary artery aneurysms and deep vein thrombosis, is a rare and an under-recognized clinical entity with less than 40 published cases in English medical literature. Vascular venous thrombotic events, as occurring in the course of Behçet's disease (BD), are also described in HSS, e. g. Read More

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http://dx.doi.org/10.1007/s00393-019-0618-7DOI Listing
March 2019
1 Read

Tubercular aortitis presenting as primary aortoenteric fistula: Report of an uncommon case.

Int J Mycobacteriol 2019 Jan-Mar;8(1):110-112

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Tubercular aortitis presenting as primary aortoenteric fistula (AEF) is a rare entity. We present a 78-year-old male who presented with upper gastrointestinal bleed and also had abdominal pain and pulsating abdominal mass and on evaluation was found to have tubercular AEF which was successfully repaired with surgery and the patient recovered with antitubercular therapy along with the surgery. This case highlights the importance of high index of suspicion with early institution of surgical repair along with antitubercular therapy for tubercular AEF with good results. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_32_19DOI Listing
March 2019
1 Read

Emphysematous Aortitis by Clostridium septicum: A Rare and Lethal Complication of Right Colon Cancer.

Eur J Vasc Endovasc Surg 2019 Mar 6. Epub 2019 Mar 6.

Department of General Surgery, Colorectal Unit, General University Hospital of Elche, Miguel Hernández University of Elche, Alicante, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2018.12.022DOI Listing
March 2019
1 Read

Diagnostic Accuracy of PET/CT Scan of the Head, Neck and Chest for Giant Cell Arteritis: The Double-Blinded Giant Cell Arteritis and PET Scan (GAPS) Study.

Arthritis Rheumatol 2019 Mar 8. Epub 2019 Mar 8.

Departments of Rheumatology, Nuclear Medicine and Anatomical Pathology, Royal North Shore Hospital, St Leonards, Sydney, NSW, 2065, Australia.

Objectives: PET/CT has not been well studied as a first-line test for giant cell arteritis (GCA). In part this is due to historical limitations in visualizing the cranial arteries. The Giant Cell Arteritis and PET Scan (GAPS) study assessed the accuracy of a newer generation PET/CT of the head, neck and chest for GCA. Read More

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http://dx.doi.org/10.1002/art.40864DOI Listing
March 2019
1 Read

Picturing Giant Cell Arteritis: Projecting Into the Future.

Arthritis Rheumatol 2019 Mar 2. Epub 2019 Mar 2.

Brigham and Women's Hospital, Boston, Massachusetts, United States.

Imaging now plays an important role in the evaluation of giant cell arteritis (GCA). A growing body of literature supports the use of ultrasound, CT, MRI and PET to assist with diagnosis. EULAR recently recommended ultrasound or high-resolution MRI as diagnostic tests for GCA involving the superficial cranial arteries; ultrasound, MRI, CT, and PET are recommended for evaluating large arteries, with the caveat that ultrasound has limited value for detecting aortitis. Read More

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http://dx.doi.org/10.1002/art.40871DOI Listing
March 2019
1 Read

Diffuse inflammatory aneurysmal aortitis secondary to Scedosporium apiospermum complex in an immunocompetent individual.

Pathology 2019 Feb 25. Epub 2019 Feb 25.

Department of Immunology, PathWest, Sir Charles Gairdner Hospital, Nedlands, WA, Australia; Medical School, University of Western Australia, Nedlands, WA, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2018.10.021DOI Listing
February 2019

Back Pain: An Ominous Harbinger of Aortitis.

Cureus 2018 Dec 11;10(12):e3711. Epub 2018 Dec 11.

Internal Medicine, University of Kentucky, Lexington, USA.

Isolated aortitis is a rare entity and was recently included in the 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides under the single organ vasculitis group. Isolated aortitis represents a challenging situation due to the lack of reliable diagnostic methodology. Here, we describe the case of a 46-year-old woman who presented with severe upper back pain. Read More

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http://dx.doi.org/10.7759/cureus.3711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373889PMC
December 2018
1 Read

IgG4-Related Aortitis.

Eur J Case Rep Intern Med 2018 27;5(9):000881. Epub 2018 Sep 27.

Department of Internal Medicine, Centro Hospitalar Conde São Januário, Macau SAR.

Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibroinflammatory condition characterized by tumefactive lesions that can affect multiple organs. Serum IgG4 levels may be elevated. Early recognition is sometimes difficult but is important to avoid irreversible organ damage. Read More

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http://dx.doi.org/10.12890/2018_000881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346820PMC
September 2018
1 Read

Infectious Aortitis: Could Early Radiology Improve Patient Outcome?

Eur J Case Rep Intern Med 2018 28;5(11):000967. Epub 2018 Nov 28.

Department of Medicine, Sealand University Hospital, Køge, Denmark.

Aortitis is a rare condition and easily overlooked. It is defined as infectious or non-infectious inflammation of the aortic wall. This report describes two cases of aortitis, demonstrating the diagnostic difficulty and how diagnostic delay could have been reduced if early radiology had been performed. Read More

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http://dx.doi.org/10.12890/2018_000967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346805PMC
November 2018
1 Read

Outcomes among 196 patients with non-infectious proximal aortitis.

Arthritis Rheumatol 2019 Feb 7. Epub 2019 Feb 7.

Division of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Objective: Non-infectious aortitis may occur in the context of a recognized systemic disease or as a topographically-limited lesion without systemic features, termed clinically-isolated aortitis (CIA). From a large population of patients in a single center dedicated to aortic diseases, we have sought to better define and stress the limitations of this diagnostic category, and suggest recommendations for care.

Methods: Records of patients undergoing thoracic aortic surgery (1996-2012) at the Cleveland Clinic were reviewed to identify 196 with histopathology-proven aortitis. Read More

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http://dx.doi.org/10.1002/art.40855DOI Listing
February 2019
4 Reads

Aortitis masquerading as intramural hematoma of the ascending aorta.

Ann Thorac Surg 2019 Jan 28. Epub 2019 Jan 28.

Division of Cardiac Surgery, University of Pittsburgh. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2018.12.049DOI Listing
January 2019
2 Reads

Aortitis and pachymeningitis: an unusual combination in granulomatosis with polyangiitis (myeloperoxidase-associated vasculitis).

BMJ Case Rep 2019 Jan 28;12(1). Epub 2019 Jan 28.

Internal Medicine, Maricopa Integrated Health System, Phoenix, Arizona, USA.

Aortitis and pachymeningitis are uncommon manifestations of the antineutrophil cytoplasmic antibody-associated vasculitides, a group of systemic autoimmune diseases mainly affecting small vessels. We present a case of a 71-year-old woman with a remote history of idiopathic chronic granulomatous pachymeningitis complicated with aortic thickening due to autoimmune aortitis. Read More

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http://dx.doi.org/10.1136/bcr-2018-226795DOI Listing
January 2019
1 Read

Imaging aortitis.

Intern Med J 2019 Jan;49(1):136-137

Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/imj.14132DOI Listing
January 2019
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Aortitis caused by : Description of two cases.

Infect Dis Rep 2018 Nov 5;10(3):7746. Epub 2018 Dec 5.

Lund University and Skåne University Hospital, Lund.

is a well-known endocarditis pathogen, however it has never been described as a cause of primary aortitis. Here we describe the first published case of thoracic aortitis and an unusual case of aortic graft infection due to , which were both managed conservatively. Read More

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http://dx.doi.org/10.4081/idr.2018.7746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315309PMC
November 2018
1 Read

Multimodalities Imaging of Immunoglobulin 4-related Cardiovascular Disorders.

Authors:
Ahmed Fathala

Curr Cardiol Rev 2019 Jan 16. Epub 2019 Jan 16.

Department of Radiology, King Fasial Hospital. Saudi Arabia.

Immunoglobulin 4 (IgG4)-related systemic disease (IgG4-RSD) is a systemic inflammatory disease characterized by elevation of serum IgG4. IgG4-RSD can affect any organ in the body, and the list of organs associated with this condition is growing steadily. IgG4-related cardiovascular disease affects the coronary arteries, heart valves, myocardium, pericardium, aorta, pulmonary and peripheral vessels. Read More

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http://dx.doi.org/10.2174/1573403X15666190117101607DOI Listing
January 2019
8 Reads

IgG4-related dacryocystitis and aortitis: A new association.

Eur J Ophthalmol 2019 Jan 15:1120672118823123. Epub 2019 Jan 15.

1 Department of Ophthalmology, Hospital Universitari i Politecnic La Fe, Valencia, Spain.

A 73-year-old woman with a history of muscular weakness and dyspnoea of unknown etiology was referred to our Ophthalmology Department for dacryocystitis. Lacrimal sac biopsy revealed IgG4 plasma cell infiltration and systemic diagnosis was done based on this, allowing an appropriate treatment to be established. To our knowledge, this is the first reported case of IgG4-related dacryocystitis associated to aortitis. Read More

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http://dx.doi.org/10.1177/1120672118823123DOI Listing
January 2019
4 Reads

Spondyloarthritis-Related Autoimmune Aortitis Complicated by Severe Aortic Regurgitation.

Circ Cardiovasc Imaging 2019 Dec;12(1):e008341

Department of Medicine and Therapeutics (W.K.C., G.T., K.K.H.K., L.T., A.P.W.L., L.S.T.), Faculty of Medicine, Chinese University of Hong Kong, SAR.

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008341DOI Listing
December 2019
1 Read

Clinical phenotypes of IgG4-related disease: an analysis of two international cross-sectional cohorts.

Ann Rheum Dis 2019 Mar 5;78(3):406-412. Epub 2019 Jan 5.

Rheumatology Unit, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Objective: IgG4-related disease (IgG4-RD) is a heterogeneous, multiorgan condition of unclear aetiology that can cause organ failure. Difficulty recognising IgG4-RD contributes to diagnostic delays. We sought to identify key IgG4-RD phenotypes. Read More

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http://dx.doi.org/10.1136/annrheumdis-2018-214603DOI Listing
March 2019
4 Reads

A Rare Case of Takayasu Arteritis With Intracranial Involvement, Aortic Valvulitis, and Giant Cell Aortitis.

J Clin Rheumatol 2018 Dec 28. Epub 2018 Dec 28.

Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA Department of Neurology, Walter Reed National Military, Medical Center, Bethesda, MD Department of Radiology, Naval Medical Center San Diego, San Diego, CA Department of Internal Medicine/Rheumatology, Naval Medical Center San Diego, San Diego, CA.

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http://dx.doi.org/10.1097/RHU.0000000000000960DOI Listing
December 2018
13 Reads

Infective Endocarditis Due to Treponema pallidum: A Case Diagnosed Using Polymerase Chain Reaction Analysis of Aortic Valve.

Can J Cardiol 2019 Jan 22;35(1):104.e9-104.e11. Epub 2018 Nov 22.

Department of Cardiology, Japanese Red Cross Musashino Hospital, Tokyo, Japan.

Syphilis is a sexually transmitted disease caused by Treponema pallidum. Syphilitic aortitis might coexist in a dysfunctional aortic valve, but the etiology remains unclear, because microbiological diagnosis is difficult. A 62-year-old man with low-grade fever was diagnosed with aortitis and infective endocarditis, due to Treponema pallidum infection, using polymerase chain reaction analysis. Read More

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http://dx.doi.org/10.1016/j.cjca.2018.11.009DOI Listing
January 2019
3 Reads

Ascending Aortic Aneurysm Secondary to Isolated Noninfectious Ascending Aortitis.

J Clin Rheumatol 2018 Dec 5. Epub 2018 Dec 5.

Division of Rheumatology and Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA.

Isolated noninfectious ascending aortitis (I-NIAA) is increasingly diagnosed at histopathologic review after resection of an ascending aortic aneurysm. PubMed was searched using the term aortitis; publications addressing the issue were reviewed, and reference lists of selected articles were also reviewed. Eleven major studies investigated the causes of an ascending aortic aneurysm or dissection requiring surgical repair: the prevalence of noninfectious aortitis ranged from 2% to 12%. Read More

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http://dx.doi.org/10.1097/RHU.0000000000000948DOI Listing
December 2018
12 Reads

[Characteristics of giant cell arteritis patients under and over 75-years-old: A comparative study on 164 patients].

Rev Med Interne 2018 Dec 17. Epub 2018 Dec 17.

Aix-Marseille université, 13284 Marseille, France; Service de médecine interne et gériatrie, hôpital Nord, AP-HM, chemin des Bourrely, 13915 Marseille cedex 15, France.

Purpose: Giant cell arteritis (GCA) is the most common vasculitis of the elderly. In order to assess the impact of age at diagnosis, we compared the characteristics of patients of less than 75 years (<75 years), to those of the 75 years and over (≥75 years).

Patients And Methods: We conducted a retrospective study on 164 patients with GCA diagnosed from 2005 to 2017. Read More

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http://dx.doi.org/10.1016/j.revmed.2018.11.004DOI Listing
December 2018
2 Reads

Case of ruptured S aortitis: presentation and management.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Internal Medicine, Albany Medical Center, Albany, New York, USA.

Infectious aortitis with the complication of aortic aneurysm carries a high mortality rate without appropriate interventions, mostly due to aortic rupture. For this reason, early and prompt diagnoses along with surgical and medical managements play critical roles. Aortic infection with (SA) is uncommon, but reported cases have been usually associated with fatal complication from rapid progression into rupture. Read More

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http://dx.doi.org/10.1136/bcr-2018-225514DOI Listing
December 2018
1 Read

[Searching the Roots of Erb's Auscultation Point].

Dtsch Med Wochenschr 2018 Dec 18;143(25):1852-1857. Epub 2018 Dec 18.

"Erb's point" is the fifth point of auscultation for the heart exam, located in the third intercostal space close to the sternum. It has sometimes been attributed to famous German neurologist Wilhelm Heinrich Erb (1840 - 1921), but without historical evidence. Erb's focus on neurology suggested that the auscultation point may have been confused with other points in the neck named after Erb. Read More

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http://dx.doi.org/10.1055/a-0596-4733DOI Listing
December 2018
4 Reads

Antineutrophil Cytoplasmic Antibody Vasculitis Causing Skull Base Inflammation and Aortitis.

Ann Indian Acad Neurol 2018 Oct-Dec;21(4):339-340

Department of Nuclear Medicine, Aster Medcity, Kochi, Kerala, India.

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http://dx.doi.org/10.4103/aian.AIAN_83_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238576PMC
December 2018
3 Reads

A case of syphilitic aortitis.

Intern Med J 2018 Dec;48(12):1549-1550

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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http://doi.wiley.com/10.1111/imj.14127
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http://dx.doi.org/10.1111/imj.14127DOI Listing
December 2018
15 Reads

A case of Brucella aortitis associated with development of thoracic aortic aneurysm and aortobronchial fistula.

Cardiovasc Pathol 2019 Mar - Apr;39:5-7. Epub 2018 Nov 7.

Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston/Memorial Hermann Hospital-Texas Medical Center, 6431 Fannin St, Houston, TX 77030, USA. Electronic address:

Objectives: The purpose of this case report is to document the occurrence of granulomatous aortitis complicated by formation of a saccular aneurysm and aortobronchial fistula due to Brucella infection.

Methods: A 65-year-old man with a history of feral swine hunting presented with hemoptysis and was found to have a saccular thoracic aortic aneurysm and associated aortobronchial fistula. The aneurysm underwent operative repair with closure of the aortobronchial fistula. Read More

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http://dx.doi.org/10.1016/j.carpath.2018.10.011DOI Listing
November 2018
8 Reads

Computed Tomography of Acquired Aortic Diseases.

Radiol Clin North Am 2019 Jan;57(1):127-139

Miami Cardiac and Vascular Institute, Baptist Health South Florida, 8900 North Kendall Drive, Miami, FL 33176, USA. Electronic address:

Computed tomography angiography (CTA) has the ability to evaluate the aortic wall and the lumen easily, quickly, and reproducibly without the need for invasive techniques. The images are isotropic, allowing several reconstructions. When imaging the aorta, CTA has replaced catheter angiography in the diagnosis of acquired disease such as aortoiliac disease, aneurysm, and infectious and inflammatory disease of the aorta. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00338389183010
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http://dx.doi.org/10.1016/j.rcl.2018.08.012DOI Listing
January 2019
10 Reads

Incidence of Aortitis in Surgical Specimens of the Ascending Aorta Clinical Implications at Follow-Up.

Semin Thorac Cardiovasc Surg 2018 Nov 7. Epub 2018 Nov 7.

Section of Cardiac Surgery, University Hospital, Pisa, Italy. Electronic address:

The objectives of this study are to evaluate the incidence of aortitis on a surgical population, establish any relationship with systemic diseases, verify early and late surgical results and provide clinical and radiological follow-up to determine factors potentially predicting progression of the disease and influencing late outcome. From 2009 to 2017, 237 patients underwent elective operations on the ascending aorta. Segments of the excised tissues were routinely sent for histologic evaluation, providing adequate data in 178 (75%) for a clinical and pathologic correlation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10430679183032
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http://dx.doi.org/10.1053/j.semtcvs.2018.10.022DOI Listing
November 2018
24 Reads

A Case of IBD Immunosuppression Related Salmonella Aortitis Requiring Emergency Vascular Grafting.

Inflamm Bowel Dis 2018 Nov 5. Epub 2018 Nov 5.

Department of Gastroenterology, Royal Preston Hospital, Fulwood, Preston, United Kingdom.

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https://academic.oup.com/ibdjournal/advance-article/doi/10.1
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http://dx.doi.org/10.1093/ibd/izy347DOI Listing
November 2018
18 Reads

[Glucocorticoid sensitive bilateral leg swelling in an 85-year-old woman presenting with polymyalgia rheumatica: A case report].

Rev Med Interne 2018 Oct 31. Epub 2018 Oct 31.

Service de rhumatologie, centre hospitalier René-Dubos, 6, avenue de l'Île-de-France, 95301 Pontoise, France. Electronic address:

Introduction: Polymyalgia rheumatica (PMR) can be associated with distal swelling indicating an associated RS3PE syndrome. We report a case of PMR associated with oedema of the lower limbs, which resolved rapidly under glucocorticoid therapy.

Case Report: A 85-year-old woman presented with a 4 month history of PMR responding to the 2012 EULAR/ACR classification criteria. Read More

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http://dx.doi.org/10.1016/j.revmed.2018.10.004DOI Listing
October 2018
3 Reads

Pulmonary Artery Compression and Invasion by a Ruptured Giant Thoracic Aortic Aneurysm: A Rare Presentation.

CASE (Phila) 2018 Oct 4;2(5):201-206. Epub 2018 May 4.

Department of Echocardiography, National Institute of Cardiology, Laranjeiras, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1016/j.case.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200667PMC
October 2018
2 Reads

Renal cystic disease in the Fbn1 Marfan mouse is associated with enhanced aortic aneurysm formation.

Cardiovasc Pathol 2019 Jan - Feb;38:1-6. Epub 2018 Oct 16.

Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Univ of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands. Electronic address:

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene (FBN1), resulting in aortic aneurysm formation and dissections. Interestingly, variable aortopathy is observed even within MFS families with the same mutation. Thus, additional risk factors determine disease severity. Read More

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http://dx.doi.org/10.1016/j.carpath.2018.10.002DOI Listing
March 2019
3 Reads

Pathogenesis of large vessel vasculitis: Implications for disease classification and future therapies.

Vasc Med 2019 Feb 24;24(1):79-88. Epub 2018 Oct 24.

4 Department of Aortovascular Surgery, Manchester Royal Infirmary, Manchester, UK.

Despite being recognised over a century ago, the aetiology and pathogenesis of large vessel vasculitis (LVV) still remains elusive. Takayasu's arteritis (TA) and giant cell arteritis (GCA) represent the two major categories of LVV, each with distinctive clinical features. Over the last 10 years an increased understanding of the immunopathogenesis of the inflammatory cascade within the aortic wall has revived the view that LVVs may represent subtypes of the same pathological process, with implications in the treatment of this disease. Read More

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http://journals.sagepub.com/doi/10.1177/1358863X18802989
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http://dx.doi.org/10.1177/1358863X18802989DOI Listing
February 2019
12 Reads
1.732 Impact Factor

Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis.

Circ Genom Precis Med 2018 Oct;11(10):e002296

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Japan (N.T., Y.M., Y.I., Y.S.-W., T.A., K.H., M.I.).

Background: Takayasu arteritis (TAK) is an autoimmune systemic arteritis of unknown pathogenesis. Genome-wide association studies revealed that single-nucleotide polymorphisms in the MLX gene encoding the MLX (Max-like protein X) transcription factor are significantly associated with TAK in Japanese patients. MLX single-nucleotide polymorphism rs665268 is a missense mutation causing the Q139R substitution in the DNA-binding site of MLX. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCGEN.118.002296
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http://dx.doi.org/10.1161/CIRCGEN.118.002296DOI Listing
October 2018
30 Reads

Aspergillus aortitis in an immunocompetent patient presenting with acute endophthalmitis.

Infect Dis Rep 2018 Sep 24;10(2):7750. Epub 2018 Sep 24.

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

is a common environmental mold most often recognized as an infectious agent in patients with severe immune compromise. We present a case of an immunocompetent patient presenting with endogenous endophthalmitis in the absence of other infectious symptoms. The search for a systemic source revealed an ascending aortic pseudoaneurysm. Read More

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https://www.pagepress.org/journals/index.php/idr/article/vie
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http://dx.doi.org/10.4081/idr.2018.7750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176472PMC
September 2018
14 Reads

Drug-induced aortitis in a patient with ovarian cancer treated with bevacizumab combination therapy.

Taiwan J Obstet Gynecol 2018 Oct;57(5):750-752

Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo, Japan. Electronic address:

Objective: To review and evaluate drug-induced vasculitis, which is an extremely rare complication of chemotherapy.

Case Report: A 47-year-old woman with ovarian cancer developed aortitis during bevacizumab combination chemotherapy. Contract-enhanced CT showed concentric thickening of the descending aorta. Read More

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http://dx.doi.org/10.1016/j.tjog.2018.08.026DOI Listing
October 2018
3 Reads

A Case of IgG4-Related Aortitis and Pericarditis: Diagnostic Challenges and Natural History.

Am J Case Rep 2018 Oct 16;19:1232-1236. Epub 2018 Oct 16.

Department of Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.

BACKGROUND IgG4-related disease (IgG4-RD) is a systemic inflammatory condition with a myriad of presentations related to the pattern of organ involvement. Diagnostic workup for IgG4-RD requires a high index of suspicion, and further workup often includes the results of serological testing for elevated levels of IgG4. Correlation of presentation, past medical history, and histopathologic analysis are required to make a diagnosis. Read More

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https://www.amjcaserep.com/abstract/index/idArt/910164
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http://dx.doi.org/10.12659/AJCR.910164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199468PMC
October 2018
21 Reads

The role of 18F-FDG positron emission tomography for the diagnosis of vasculitides.

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):108-114. Epub 2018 Oct 1.

Rheumazentrum Ruhrgebiet, Herne, and Ruhr University, Bochum, Germany.

Large-vessel vasculitis is the most common form of primary vasculitis comprising cranial and large-vessel giant cell arteritis, Takayasu's arteritis and idiopathic aortitis. Prompt diagnosis and treatment of large-vessel vasculitis are important to prevent potentially serious emergencies such as visual loss, vascular stenosis and aneurysm formation. Temporal artery biopsy has long been the standard for diagnosing GCA - an invasive technique that lacks sensitivity compared to a clinical diagnosis that relies on a combination of clinical symptoms, elevated serum inflammatory markers and imaging findings. Read More

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January 2019
7 Reads

Idiopathic aortitis presenting as pyrexia of unknown origin and delirium.

Br J Hosp Med (Lond) 2018 Oct;79(10):586-587

Consultant Rheumatologist, Department of Rheumatology, St Thomas' Hospital, London.

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http://www.magonlinelibrary.com/doi/10.12968/hmed.2018.79.10
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http://dx.doi.org/10.12968/hmed.2018.79.10.586DOI Listing
October 2018
5 Reads

IgG4-related Cardiovascular Disease from the Aorta to the Coronary Arteries: Multidetector CT and PET/CT.

Radiographics 2018 Nov-Dec;38(7):1934-1948. Epub 2018 Oct 5.

From the Department of Diagnostic and Interventional Radiology (N.O.M., S.Y., F.K., K.K.) and Department of Surgical Pathology (H.K.O.), Hokkaido University Hospital, N14, W5, Kita-ku, Sapporo, Japan 060-8638; and Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan (O.M.).

Immunoglobulin G4 (IgG4)-related disease can affect the cardiovascular system, including the coronary arteries and pericardium and especially the walls of large and medium-sized vessels. The presence of coronary involvement is critical, as this condition can cause myocardial ischemia or sudden cardiac death. Although histopathologic examination remains the reference standard for detecting organ involvement and diagnosing IgG4-related disease, obtaining biopsy or surgical specimens from the vessel wall is still challenging. Read More

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http://pubs.rsna.org/doi/10.1148/rg.2018180049
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http://dx.doi.org/10.1148/rg.2018180049DOI Listing
October 2018
5 Reads

Role of PET/CT in the Evaluation of Aortic Disease.

Chonnam Med J 2018 Sep 27;54(3):143-152. Epub 2018 Sep 27.

Department of Nuclear Medicine, Chonnam National University Hospital, Gwangju, Korea.

Positron emission tomography (PET) /computed tomography (CT) has been established as a standard imaging modality in the evaluation of malignancy. Although PET/CT has played a major role in the management of oncology patients, its clinical use has also increased for various disorders other than malignancy. Growing evidence shows that PET/CT images have many advantages in aortic disease as well. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4068/cmj.2018.54
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http://dx.doi.org/10.4068/cmj.2018.54.3.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165921PMC
September 2018
7 Reads

Diagnosis and differential diagnosis of large-vessel vasculitides.

Rheumatol Int 2019 Feb 17;39(2):169-185. Epub 2018 Sep 17.

Division of Rheumatology, Department of Internal Medicine, Ege University School of Medicine, Bornova, Izmir, Turkey.

There are no universally accepted diagnostic criteria for large-vessel vasculitides (LVV), including giant cell arteritis (GCA) and Takayasu arteritis (TAK). Currently, available classification criteria cannot be used for the diagnosis of GCA and TAK. Early diagnosis of these two diseases is quite challenging in clinical practice and may be accomplished only by combining the patient symptoms, physical examination findings, blood test results, imaging findings, and biopsy results, if available. Read More

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http://dx.doi.org/10.1007/s00296-018-4157-3DOI Listing
February 2019
17 Reads

Analysis of In Vivo Serpin Functions in Models of Inflammatory Vascular Disease.

Methods Mol Biol 2018 ;1826:157-182

Center for Personalized Diagnostics and Center for Immunotherapy, Vaccines and Virotherapy, Biodesign Institute, Arizona State University, Tempe, AZ, USA.

Serpins have a wide range of functions in regulation of serine proteases in the thrombotic cascade and in immune responses, representing up to 2-10% of circulating proteins in the blood. Selected serpins also have cross-class inhibitory actions for cysteine proteases in inflammasome and apoptosis pathways. The arterial and venous systems transport blood throughout the mammalian body representing a central site for interactions between coagulation proteases and circulating blood cells (immune cells) and target tissues, a very extensive and complex interaction. Read More

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http://dx.doi.org/10.1007/978-1-4939-8645-3_11DOI Listing
March 2019
13 Reads

Eosinophilic aortitis with thoracic aortic aneurysm and rupture in a captive-born owl monkey.

J Med Primatol 2018 Dec 6;47(6):423-426. Epub 2018 Sep 6.

Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Eosinophilic aortitis is a rare condition in animals and humans, and it has been occasionally reported associated with parasitic migration and with a poorly understood complex group of autoimmune vasculitides. Here, we describe a case of eosinophilic aortitis with thoracic aortic aneurysm and rupture in a captive-born owl monkey and discuss the differential diagnoses. Read More

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http://dx.doi.org/10.1111/jmp.12373DOI Listing
December 2018
8 Reads

Clinical presentation, treatment and outcome of Takayasu's arteritis in southern Chinese: a multicenter retrospective study.

Rheumatol Int 2018 Dec 4;38(12):2263-2270. Epub 2018 Sep 4.

Department of Medicine & Geriatrics, Tai Po Hospital, Hong Kong SAR, China.

To study the clinical presentation, treatment and outcome of southern Chinese patients with Takayasu's arteritis (TA). This is a retrospective chart review study of 78 patients managed in 14 public hospitals in Hong Kong between the years 2000 and 2010. Patients were identified from the hospital registry using the ICD-10 diagnostic code of the disease. Read More

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http://dx.doi.org/10.1007/s00296-018-4150-xDOI Listing
December 2018
11 Reads

Aortitis Presenting as Fever of Unknown Origin.

Ann Thorac Cardiovasc Surg 2018 Dec 29;24(6):279-287. Epub 2018 Aug 29.

Department of Cardiology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, Fujian, China.

Patients with aortitis often present with nonspecific constitutional symptoms. Due to the fact that aortitis is associated with inflammatory or infectious courses, patients may manifest fever or fever of unknown origin. Such clinical characteristics of aortitis are unavoidably brought about diagnostic dilemmas and might lead to a series of unnecessary work-ups and maltreatment. Read More

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http://dx.doi.org/10.5761/atcs.ra.18-00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300425PMC
December 2018
26 Reads