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    1 OF 965

    Normalization of Diffuse ST-Depression with aVR Elevation After Rehydration in a Patient with Severe Aortic Stenosis.
    Am J Case Rep 2017 May 22;18:563-567. Epub 2017 May 22.
    Center for Medicine.
    BACKGROUND Isolated ST elevation in lead aVR in combination with global ST depression with normalization after rehydration is a unique electrocardiographic pattern that is associated with a broad range of diagnoses. Its association with left main coronary artery disease and other acute coronary syndromes suggest the need for early and aggressive cardiac evaluation. CASE REPORT A 53-year-old man presented with altered mental status and loss of consciousness. Read More

    Prognostic Impact of Low-Flow Severe Aortic Stenosis in Small-Body Patients Undergoing TAVR: The OCEAN-TAVI Registry.
    JACC Cardiovasc Imaging 2017 May 11. Epub 2017 May 11.
    Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
    Objectives: This study aimed to analyze the prognostic impact of low-flow (LF) severe aortic stenosis in small-body patients undergoing transcatheter aortic valve replacement (TAVR).

    Background: Western literature demonstrates a poor prognosis with paradoxical LF and low-flow low-gradient (LF-LG) severe aortic stenosis (AS), as defined by stroke volume index (SVi) <35 ml/m(2) and mean pressure gradient <40 mm Hg with preserved left ventricular ejection fraction (LVEF). However, this poor prognosis is contested in Japan owing to the smaller body size of Japanese patients relative to that of Western patients. Read More

    Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve: The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomized Clinical Trial.
    JACC Cardiovasc Interv 2017 May 11. Epub 2017 May 11.
    Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
    Objective: The aim of this study was to compare aspirin plus clopidogrel with aspirin alone as antithrombotic treatment following transcatheter aortic valve replacement (TAVR) for the prevention of ischemic events, bleeding events, and death.

    Background: Few data exist on the optimal antithrombotic therapy following TAVR.

    Methods: This was a randomized controlled trial comparing aspirin (80 to 100 mg/day) plus clopidogrel (75 mg/day) (dual-antiplatelet therapy [DAPT]) versus aspirin alone (single-antiplatelet therapy [SAPT]) in patients undergoing TAVR with a balloon-expandable valve. Read More

    1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses.
    JACC Cardiovasc Interv 2017 May;10(10):1034-1044
    Department of Internal Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
    Objectives: This study evaluated the safety and effectiveness of self-expanding transcatheter aortic valve replacement (TAVR) in patients with surgical valve failure (SVF).

    Background: Self-expanding TAVR is superior to medical therapy for patients with severe native aortic valve stenosis at increased surgical risk.

    Methods: The CoreValve U. Read More

    Multiple causes of syncope in the elderly: diagnostic outcomes of a Dutch multidisciplinary syncope pathway.
    Europace 2017 May 17. Epub 2017 May 17.
    Department of Geriatric Medicine, Northwest Clinics, Wilhelminalaan 12, 1815 JD, Alkmaar, The Netherlands.
    Aims: To assess the diagnostic outcomes of a multidisciplinary pathway for elderly syncope patients.

    Methods And Results: Observational cohort study at a Fall and Syncope Clinic, including consecutive syncope patients aged ≥65 years between 2011 and 2014. Measurements: The sort, number, and accuracy of diagnoses resulting in syncope. Read More

    Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome.
    Int J Cardiovasc Imaging 2017 May 17. Epub 2017 May 17.
    Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Drive Room H2103, Stanford, CA, 94305, USA.
    Valvulo-arterial impedance (Zva) has been shown to predict worse outcome in medically managed aortic stenosis (AS) patients. We aimed to investigate the association between Zva and left ventricular (LV) adaptation and to explore the predictive value of Zva for cardiac functional recovery and outcome after transcatheter aortic valve replacement (TAVR). We prospectively enrolled 128 patients with AS who underwent TAVR. Read More

    [Choosing wisely recommendations in angiology].
    Internist (Berl) 2017 May 17. Epub 2017 May 17.
    Praxisklinik Herz und Gefäße, Akademische Lehrpraxisklinik der TU Dresden, Forststr. 3, 01099, Dresden, Deutschland.
    Background: The Choosing wisely initiative addresses measures of high medical impact which are frequently not appropriately performed according to expert opinion.

    Objective: To increase the quality of indications by providing supportive information on diagnostic and therapeutic measures in the field of angiology.

    Materials And Methods: As part of the Choosing wisely initiative, the German Society of Angiology has constructed five positive recommendations on underused measures and five negative recommendations concerning those possibly overused. Read More

    Combined Transapical Transcatheter Aortic Valve Replacement and Thoracic Endovascular Aortic Repair for Severe Aortic Stenosis and Arch Aneurysm.
    Aorta (Stamford) 2016 Oct 1;4(5):175-177. Epub 2016 Oct 1.
    Aortic Center, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.
    An 83-year-old male with multiple comorbidities presented with critical aortic stenosis and a saccular aortic arch aneurysm. Through a mini thoracotomy, a balloon expandable transcatheter aortic valve was delivered transapically. A thoracic stent graft was then delivered through the prosthetic valve and deployed in the arch, while a covered stent was deployed in the left common carotid artery. Read More

    Iatrogenic Supravalvular Aortic Stenosis.
    Aorta (Stamford) 2016 Oct 1;4(5):172-174. Epub 2016 Oct 1.
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridgeshire, UK.
    We describe a case of hemolytic anemia and proximal anastomotic site stenosis following emergency repair of a Type A aortic dissection. This rare complication led to a reoperation to correct the iatrogenic aortic stenosis and cure the consequent hemolysis. A "sandwich" technique (with two Teflon strips on the outside and inside of the aortic wall) was used in the initial repair to reinforce the suture line and prevent bleeding from the aortic anastomoses. Read More

    Conservative management of aortic root rupture complicated with cardiac tamponade following transcatheter aortic valve implantation.
    World J Cardiol 2017 Apr;9(4):391-395
    Luca Vannini, Rut Andrea, Manel Sabaté, Department of Cardiology, Hospital Clínic, 08036 Barcelona, Spain.
    Aortic root rupture and cardiac tamponade during transcatheter aortic valve implantation is a frightening complication with high mortality rate. A conservative management of this complication could represent an initial strategy, especially in high-risk patients, to avoid emergent cardiac surgery. This conservative management includes: Immediate detection of pericardial effusion by echocardiography, a fast instauration of pericardial drainage, auto-transfusion and anticoagulation reversal. Read More

    Transcatheter aortic valve implantation: the transaortic approach.
    Asian Cardiovasc Thorac Ann 2017 Jan 1:218492317702027. Epub 2017 Jan 1.
    1 Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
    Background Transcatheter aortic valve implantation has been established as a safe and effective treatment option for patients at high or prohibitive surgical risk. However, some patients may not be suitable for the transfemoral approach due to severe iliofemoral disease or aneurysmal disease of the thoracoabdominal aorta. The aim of this case series was to evaluate the feasibility and clinical outcomes of the transaortic approach. Read More

    [Comparison of aortic annular diameter defined by different measurement mordalities before transcatheter aortic valve implantation].
    Zhonghua Xin Xue Guan Bing Za Zhi 2017 May;45(5):409-414
    Heart Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
    Objective: To compare aortic annular diameter measured by transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and multislice computed tomography (MSCT) in patients with severe aortic stenosis, and to evaluate the impact on selection of prosthetic valve type in transcatheter aortic valve implantation (TAVI). Methods: Clinical data of 138 patients with severe aortic stenosis referred for TAVI between January 2014 and June 2016 in our hospital were retrospectively analyzed.The difference of aortic annular diameter measured by TTE, TEE, and MSCT were compared. Read More

    Ross-Konno Procedure With Cylinder Mitral Valve Replacement in 49 Days Old Infant.
    World J Pediatr Congenit Heart Surg 2017 Jan 1:2150135116688173. Epub 2017 Jan 1.
    1 Department of Cardiac Surgery, Ukrainian Children's Cardiac Center, Kyiv, Ukraine.
    A neonate with antenatally diagnosed severe aortic valve stenosis, left ventricular outflow tract obstruction, left ventricular endocardial fibroelastosis, and severe mixed mitral valve disease was admitted to our center for balloon aortic valvuloplasty. On day 49, we performed a Ross-Konno procedure and mitral valve replacement on the baby, whose weight was 3.4 kg. Read More

    Comparison of preoperative and intraoperative assessment of aortic stenosis severity by echocardiography.
    Br J Anaesth 2017 May;118(5):699-704
    Department of Anaesthesia and Acute Pain Medicine, St Vincent's Hospital, Melbourne, Victoria Parade, PO Box 2900, Fitzroy, VIC 3065, Australia.
    Background: General anaesthesia and surgically induced changes in cardiac loading conditions may alter flow across the aortic valve. This study examined how echocardiographic assessment of the severity of aortic stenosis (AS) changes during surgery.

    Methods: Patients who underwent aortic valve replacement for any severity of AS between July 2007 and June 2015 were identified. Read More

    A case of histopathologically confirmed infective endocarditis with no vegetations observed during preoperative diagnosis.
    CEN Case Rep 2016 May 9;5(1):113-116. Epub 2015 Dec 9.
    Department of Nephrology, Saitama Sekishinkai Hospital, 1-33, Unoki, Sayama, Saitama, Japan.
    An 81-year-old woman on maintenance hemodialysis (HD) was admitted to the hospital with fever and repeated positive blood cultures for coagulase-negative staphylococci. The patient had a history of aortic valve replacement for aortic valve stenosis (AS). Although one major criterion and two minor criteria from the Duke criteria were met and therefore infective endocarditis (IE) was suspected for this case, no definitive diagnosis was made. Read More

    Lipoprotein(a): A Lipoprotein Whose Time Has Come.
    Curr Treat Options Cardiovasc Med 2017 Jul;19(7):48
    Division of Cardiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
    Opinion Statement: Cardiovascular disease is a leading cause of morbidity and mortality in the USA and around the world. While we are now able to achieve significant low-density lipoprotein cholesterol (LDL-C) lowering with current therapies, many patients remain at risk for cardiovascular disease (CVD). Elevated lipoprotein(a) [Lp(a)] has been shown to be an independent risk factor for CVD and accounts for some of the residual CVD risk after LDL-C lowering in several large clinical trials. Read More

    Stress Testing in Asymptomatic Aortic Stenosis.
    Circulation 2017 May;135(20):1956-1976
    From Clinical Trials Center, Cardiovascular Research Foundation, New York (B.R., D.B., M.B.L., P.G.); Sahlgrenska University Hospital, Gothenburg, Sweden (B.R.); Pulmonary Hypertension and Vascular Biology Research Group, Laval University, Québec, Canada (P.P.); Gagnon Cardiovascular Institute, Morristown Medical Center, NJ (L.D.G., P.G.); Columbia University Medical Center, New York (D.B., M.B.L., P.G.); Leiden University Medical Center, The Netherlands (J.J.B.); Structural Heart and Valve Center, Vanderbilt University Medical Center, Nashville, TN (B.R.L.); Northwestern University Feinberg School of Medicine, Chicago, IL (R.O.B.); Brigham and Women's Hospital, Harvard Medical School, Boston, MA (P.T.O.); and Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Québec, Canada (P.G.).
    Aortic stenosis is 1 of the most common heart valve diseases among adults. When symptoms develop, prognosis is poor, and current guidelines recommend prompt aortic valve replacement. Depending of the severity of the aortic stenosis and the presence of concomitant heart disease and medical comorbidities, stress testing represents a reasonable strategy to help better risk stratify asymptomatic patients. Read More

    Insights into the Need for Permanent Pacemaker Following Implantation of the Repositionable LOTUS™ Valve for the Transcatheter Aortic Valve Replacement in 250 Patients: Results from the REPRISE II Trial With Extended Cohort.
    EuroIntervention 2017 May 16. Epub 2017 May 16.
    Clinique Pasteur, Toulouse, France.
    Aims: This analysis evaluated the incidence and predictors of the need for permanent pacemaker (PPM) implantation following implantation of the repositionable and fully retrievable Lotus Aortic Valve Replacement System.

    Methods & Results: The prospective, single arm, multicentre REPRISE II study with extended cohort enrolled 250 symptomatic, high surgical risk patients with severe aortic stenosis for transfemoral transcatheter aortic valve implantation (TAVI) with a 23mm or 27mm Lotus Valve. Echocardiography, computed tomography, and electrocardiography data were evaluated by independent core labs. Read More

    Virtual Resting Pd/Pa From Coronary Angiography and Blood Flow Modelling: Diagnostic Performance Against Fractional Flow Reserve.
    Heart Lung Circ 2017 May 3. Epub 2017 May 3.
    Second Department of Cardiology, Medical School, University of Ioannina, Greece.
    Background: Fractional flow reserve (FFR) has been established as a useful diagnostic tool. The distal coronary pressure to aortic pressure (Pd/Pa) ratio at rest is a simpler physiologic index but also requires the use of the pressure wire, whereas recently proposed virtual functional indices derived from coronary imaging require complex blood flow modelling and/or are time-consuming. Our aim was to test the diagnostic performance of virtual resting Pd/Pa using routine angiographic images and a simple flow model. Read More

    Thrombin generation and intracranial atherosclerotic disease in patients with a transient ischaemic attack.
    Thromb Res 2017 May 9;155:72-77. Epub 2017 May 9.
    Angiology and Blood Coagulation Unit, S. Orsola-Malpighi University Hospital, 40138 Bologna, Italy.
    Background: Intracranial atherosclerotic disease (ICAD) is responsible for at least 10% of transient ischaemic attacks (TIA). Thrombin generation has been shown to be associated with several atherosclerotic conditions and may be relevant in the pathogenesis of TIA from ICAD.

    Objective: To evaluate the association between thrombin generation and ICAD in patients with TIA. Read More

    Transcatheter aortic valve implantation in patients at intermediate surgical risk.
    Int J Cardiol 2017 May 4. Epub 2017 May 4.
    Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy; URT of IFC of the CNR, Magna Graecia University, Catanzaro, Italy. Electronic address:
    Transcatheter Aortic Valve Implantation (TAVI) has revolutionized the treatment of elderly patients with symptomatic severe aortic stenosis (AS). Initially tested in unoperable or high surgical risk patients, the safety and efficacy of TAVI has progressively improved, with increasing operators' experience and continuous technical refinements of the devices and of the delivery systems. Hence, the extension of clinical indications for TAVI to the intermediate-risk population has been attracting cardiologists in recent years. Read More

    A cohort study reveals myocarditis to be a rare and life-threatening presentation of large vessel vasculitis.
    Semin Arthritis Rheum 2017 Apr 4. Epub 2017 Apr 4.
    Rheumatology Department, Imperial College Healthcare NHS Trust and Imperial College London, Hammersmith Hospital, London, UK.
    Background: The predominant forms of adult large vessel vasculitis (LVV) are giant cell arteritis (GCA) and Takayasu arteritis (TA). Cardiac involvement in LVV is a cause of morbidity and mortality, particularly in TA. Cardiac failure is most commonly secondary to uncontrolled arterial hypertension or myocardial ischaemia. Read More

    Feasibility and safety of transfemoral sheathless portico aortic valve implantation: Preliminary results in a single center experience.
    Catheter Cardiovasc Interv 2017 May 13. Epub 2017 May 13.
    Heart Valve Clinic, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
    Background: Feasibility of transfemoral (TF) transcathteter aortic valve replacement (TAVR) is limited by the smallest diameter, the calcification and tortuosity of the iliofemoral access vessels. The use of the Portico system without delivery sheath results in significantly lower profile delivery system compared to standard technique. We herein report our single center experience, feasibility and safety of such an approach. Read More

    High- Versus Low-Gradient Severe Aortic Stenosis: Demographics, Clinical Outcomes, and Effects of the Initial Aortic Valve Replacement Strategy on Long-Term Prognosis.
    Circ Cardiovasc Interv 2017 May;10(5)
    From the Department of Cardiovascular Medicine (T.T., H.S., S.M., E.M.-M., T. Kato, N.S., T. Kimura) and Department of Cardiovascular Surgery (K. Minatoya), Kyoto University Graduate School of Medicine, Japan; Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Kokura Memorial Hospital, Kitakyushu, Japan (K.A.); Shimada Municipal Hospital, Japan (N.K.); Shizuoka City Shizuoka Hospital, Japan (K. Murata); Kobe City Medical Center General Hospital, Japan (T.K.); Kurashiki Central Hospital, Japan (Y.K.); Tenri Hospital, Japan (C.I., M.M.); Kindai University, Nara Hospital, Higashiosaka, Japan (H.M.); Mitsubishi Kyoto Hospital, Kyoto, Japan (M.K.); Kindai University Hospital, Higashiosaka, Japan (Y.H.); Osaka Red Cross Hospital, Japan (T.I., K.N.); Koto Memorial Hospital, Higashiomi, Japan (T. Murakami); Shizuoka General Hospital, Japan (Y.T.); Nishikobe Medical Center, Kobe, Japan (K.Y.); Japanese Red Cross Wakayama Medical Center, Japan (M. T.); National Hospital Organization Kyoto Medical Center, Japan (M. Ishii); Kitano Hospital, Osaka, Japan (M. Inoko); Hikone Municipal Hospital, Japan (T.I.); Kansai Electric Power Hospital, Japan (A.K., K.I.); Hyogo Prefectural Amagasaki General Medical Center, Japan (K.H.); Japanese Red Cross Otsu Hospital, Japan (N.H., T.J.); Saiseikai Noe Hospital, Osaka, Japan (Y.K.); Shiga Medical Center for Adults, Moriyama, Japan (Y.I.); Hamamatsu Rosai Hospital, Japan (C.M.); and Hirakata Kohsai Hospital, Japan (Y.M.).
    Background: There is considerable debate on the management of patients with low-gradient severe aortic stenosis (LG-AS), defined as aortic valve area <1 cm(2) with peak aortic jet velocity ≤4.0 m/s, and mean aortic pressure gradient ≤40 mm Hg.

    Methods And Results: In the CURRENT AS registry (Contemporary Outcomes After Surgery and Medical Treatment in Patients With Severe Aortic Stenosis), there were 2097 patients (initial aortic valve replacement [AVR] strategy: n=977, and conservative strategy: n=1120) with high-gradient severe aortic stenosis (HG-AS) and 1712 patients (initial AVR strategy: n=219, and conservative strategy: n=1493) with LG-AS. Read More

    Feasibility and relevance of right parasternal view for assessing severity and rate of progression of aortic valve stenosis in primary care.
    Int J Cardiol 2017 May 3. Epub 2017 May 3.
    Cardiology Service, CMSR Veneto Medica, Altavilla Vicentina, Italy.
    Background: Right parasternal view (RPV) is important in assessing the severity of aortic stenosis (AS). However, the feasibility and relevance of RPV in primary care is unresolved. Moreover, information regarding the role of RPV in the evaluation of the hemodynamic progression of AS is lacking. Read More

    Takayasu's Arteritis Presenting with Headache and Peripheral Facial Palsy: A Case Report.
    J Tehran Heart Cent 2016 Oct;11(4):195-197
    Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
    Takayasu's arteritis (TA) is a rare case of granulomatous arteritis which mainly involves the aorta and its large branches. Although arterial hypertension is the most common feature of the disease in both adults and children, patients with TA may present with numerous clinical manifestations. Our patient was a 45-year-old woman, known to have hypertension from 3 years earlier following assessments made for severe headache. Read More

    [Surgical Treatment for Anomalous Aortic Origin of Coronary Arteries].
    Kyobu Geka 2017 May;70(5):342-347
    Department of Cardiovascular Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
    Anomalous aortic origin of coronary arteries is rare. We report 3 cases of surgical treatment for anomalous aortic origin of coronary arteries. Case 1 was a 38-year-old man who was saved by the use of an automated external defibrillator from cardiopulmonary arrest while exercising. Read More

    Computed tomography angiography reveals stenosis and aneurysmal dilation of an aberrant right subclavian artery causing systemic blood pressure misreading in an old Pekinese dog.
    J Vet Med Sci 2017 May 11. Epub 2017 May 11.
    Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University.
    A 14-year-old dog weighing 4 kg presented with hypotension only in the right forelimb. Thoracic radiography revealed a round soft tissue opacity near the aortic arch and below the second thoracic vertebra on a lateral view. Three-dimensional computed tomography angiography clearly revealed stenosis and aneurysmal dilation of an aberrant right subclavian artery. Read More

    Morbidity and Mortality Associated With Balloon Aortic Valvuloplasty: A National Perspective.
    Circ Cardiovasc Interv 2017 May;10(5)
    From the Department of Cardiovascular Diseases (M.A., C.J.Z., M.S., R.A.N., M.F.E., V.T.N., G.S.S., R.G., D.R.H., C.S.R.) and Division of Cardiac Surgery, Department of Surgery (K.L.G.), Mayo Clinic College of Medicine, Rochester, MN; and Division of Cardiovascular Diseases, Department of Medicine, Temple University School of Medicine, Philadelphia, PA (R.B.).
    Background: The introduction of transcatheter aortic valve replacement (TAVR) led to renewed interest in balloon aortic valvuloplasty (BAV). We sought to assess contemporary trends in BAV utilization and their outcomes.

    Methods And Results: The Nationwide Inpatient Sample was used to identify patients who underwent BAV between 2004 and 2013. Read More

    How to Image Congenital Left Heart Obstruction in Adults.
    Circ Cardiovasc Imaging 2017 May;10(5)
    From the Seattle Adult Congenital Heart Service, University of Washington Medical Center (E.V.K., K.K.S.); Seattle Children's Hospital, Washington (E.V.K., K.K.S.); Department of Medicine, Division of Cardiology, University of Washington School of Medicine, Seattle (E.V.K., K.K.S.); and Labatt Family Heart Centre, Department of Pediatrics, and Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, ON, Canada (L.G.-W.).

    Increased Left Ventricular Diastolic Stiffness is Associated with Heart Failure Symptoms in Aortic Stenosis Patients with Preserved Ejection Fraction.
    J Card Fail 2017 May 8. Epub 2017 May 8.
    Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
    Background: Clinical risk factors associated with heart failure (HF) symptoms in aortic stenosis (AS) patients with preserved ejection fraction (EF) have not been fully identified. We hypothesized that left ventricular (LV) diastolic stiffness is associated with HF symptoms in patients with AS.

    Methods And Results: We retrospectively evaluated 275 patients with at least moderate AS (aortic valve area < 1. Read More

    Aortic Valve Stenosis Increases Helical Flow and Flow Complexity: A Study of Intra-operative Cardiac Vector Flow Imaging.
    Ultrasound Med Biol 2017 May 8. Epub 2017 May 8.
    Radiology Department, Rigshospitalet, Denmark.
    Aortic valve stenosis alters blood flow in the ascending aorta. Using intra-operative vector flow imaging on the ascending aorta, secondary helical flow during peak systole and diastole, as well as flow complexity of primary flow during systole, were investigated in patients with normal, stenotic and replaced aortic valves. Peak systolic helical flow, diastolic helical flow and flow complexity during systole differed between the groups (p < 0. Read More

    Assessment of left ventricular function with tissue Doppler echocardiography and of B-type natriuretic peptide levels in patients undergoing transcatheter aortic valve implantation.
    Rev Port Cardiol 2017 May 9;36(5):377-383. Epub 2017 May 9.
    Mus State Hospital, Department of Emergency Medicine, Antalya, Turkey.
    Introduction: Transcatheter aortic valve implantation (TAVI) is an emerging minimally invasive treatment modality in high surgical risk or inoperable patients.

    Aim: The aim of this study was to ascertain the effect of TAVI on left ventricular (LV) systolic and diastolic function and serum B-type natriuretic peptide (BNP) levels in high surgical risk or inoperable patients with severe aortic stenosis.

    Methods: Fifty-five patients were included in our retrospective study. Read More

    Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction.
    J Am Coll Cardiol 2017 May;69(19):2383-2392
    Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:
    Background: Left ventricular (LV) systolic dysfunction and moderate aortic stenosis (AS) are more frequent with advancing age and often coexist. Afterload reduction is the mainstay of pharmacological treatment of heart failure (HF). Aortic valve replacement (AVR) is only formally indicated for symptomatic severe AS. Read More

    Alcohol consumption, cigarette smoking, and incidence of aortic valve stenosis.
    J Intern Med 2017 May 11. Epub 2017 May 11.
    Centre for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
    Background: Alcohol consumption and cigarette smoking are modifiable lifestyle factors with important impact on public health. It is unclear whether these factors influence the risk of aortic valve stenosis (AVS).

    Objective: To investigate the associations of alcohol consumption and smoking, including smoking intensity and time since cessation, with AVS incidence in two prospective cohorts. Read More

    Association Between Hospital Volume and 30-Day Readmissions Following Transcatheter Aortic Valve Replacement.
    JAMA Cardiol 2017 May 11. Epub 2017 May 11.
    Brown University, Providence, Rhode Island.
    Importance: With the approval of transcatheter aortic valve replacement (TAVR) for patients with severe symptomatic aortic stenosis at intermediate surgical risk, TAVR volume is projected to increase exponentially in the United States. The 30-day readmission rate for TAVR was recently reported at 17.9%. Read More

    Rapid-deployment aortic valve replacement versus standard bioprosthesis implantation.
    J Card Surg 2017 May 11. Epub 2017 May 11.
    University Hospital of Lausanne, Cardiovascular Research Unit, Lausanne, Switzerland.
    Objective: To compare the outcome and the 1-year hemodynamic results of the rapid-deployment Intuity valve versus the Perimount Magna bioprosthesis in matched populations.

    Methods: Between March 2014 and May 2015, 32 patients underwent aortic valve replacement with the Intuity valve (Intuity-group). These patients were compared to a matched population of Perimount valves implanted during the same period of time (Perimount-group). Read More

    [Lotus Sadra valve implantation complicated by type B aortic dissection: diagnosis and treatment].
    G Ital Cardiol (Rome) 2017 Apr;18(4):325-328
    U.O.C. Cardiologia Interventistica, AORN dei Colli-Monaldi, Napoli.
    Transcatheter aortic valve implantation (TAVI) is a validated technique for the treatment of aortic valve stenosis in patients with high surgical risk or inoperable. We present the case of an 80-year-old woman with severe aortic valve stenosis (mean gradient 55 mmHg), mild surgical risk, who refused traditional surgery. We implanted a Lotus Sadra 25 mm (Boston Scientific, Marlborough, MA, USA) via the transfemoral route. Read More

    Valvular Hemolysis Masquerading as Prosthetic Valve Stenosis.
    Cureus 2017 Apr 8;9(4):e1143. Epub 2017 Apr 8.
    Cardiology, East Tennessee State University.
    The evaluation of prosthetic valves can provide a unique challenge, and a thoughtful approach is required. High output states like anemia should be kept in the differential when evaluating elevated gradients across prosthetic valves. We present the case of a 69-year-old man with a Starr-Edwards prosthetic aortic valve who presented with symptoms of congestive heart failure and high transvalvular pressure gradients. Read More

    [Concomitant Surgery for Symptomatic Severe Carotid Artery Stenosis and Aortic Valve Stenosis with Contralateral Internal Carotid Artery Occlusion:A Case Report].
    No Shinkei Geka 2017 May;45(5):409-415
    Department of Neurosurgery, Prefectural Okinawa Nanbu Medical Center and Childre's Medical Center.
    We report a case of concomitant carotid endarterectomy(CEA)and aortic valve replacement(AVR)for symptomatic severe carotid artery and aortic valve stenosis(AS). A 77-year-old man, presented to our hospital with AS complicated by right internal carotid artery(ICA)stenosis and left ICA occlusion, seeking treatment for AS. He suffered from left hemiparesis, and diffusion-weighted magnetic resonance imaging(MRI)showed multiple ischemic lesions in the right cerebral hemisphere. Read More

    Contemporary natural history of bicuspid aortic valve disease: a systematic review.
    Heart 2017 May 10. Epub 2017 May 10.
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.
    We performed a systematic review of the current state of the literature regarding the natural history and outcomes of bicuspid aortic valve (BAV). PubMed and the reference lists of the included articles were searched for relevant studies reporting on longitudinal follow-up of BAV cohorts (mean follow-up ≥2 years). Studies limited to patients undergoing surgical interventions were excluded. Read More

    Balloon aortic valvuloplasty in contemporary practice.
    J Interv Cardiol 2017 May 9. Epub 2017 May 9.
    Royal Stoke University Hospital, University Hospital of North Midlands, Stoke on Trent, Staffordshire, United Kingdom.
    Background: There has been a revival of balloon aortic valvuloplasty (BAV) for severe aortic stenosis, as a result of an increasing number of patients undergoing trans-catheter aortic valve implantation (TAVI). However, there has not been universal adoption of BAV as a standalone, nor bridging therapy.

    Methods: A retrospective analysis of the practice at our institution between June 2009 and May 2016 was performed. Read More

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