26,100 results match your criteria Aortic Regurgitation


Antineutrophil cytoplasmic antibodies (ANCA)-positive patient with infective endocarditis and chronic hepatitis B virus: a case report and review of the literature.

J Med Case Rep 2020 Jul 6;14(1):90. Epub 2020 Jul 6.

Division of Nephrology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.

Background: Antineutrophil cytoplasmic antibodies comprise a family of autoantibodies that are often used as biomarkers for certain forms of small-vessel vasculitis; however, chronic infections tend to induce the production of antineutrophil cytoplasmic antibodies. Infective endocarditis and hepatitis B virus infection have been reported to exhibit antineutrophil cytoplasmic antibody positivity and to mimic antineutrophil cytoplasmic antibody-associated vasculitis, which may lead to misdiagnosis and inappropriate treatment.

Case Presentation: We report a case of a 46-year-old Han Chinese man with untreated chronic hepatitis B virus infection who featured proteinase-3 antineutrophil cytoplasmic antibody positivity while hospitalized with infective endocarditis. Read More

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http://dx.doi.org/10.1186/s13256-020-02373-1DOI Listing

THE NEOCHORD PROCEDURE AFTER FAILED SURGICAL MITRAL VALVE REPAIR.

Semin Thorac Cardiovasc Surg 2020 Jul 1. Epub 2020 Jul 1.

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Italy. Electronic address:

Surgical mitral valve reintervention is associated with significant morbidity and mortality, and repeat repair is not always feasible. We examine the clinical outcomes of the NeoChord procedure after failed conventional mitral valve repair. A total of 312 patients were treated with the NeoChord repair procedure between January 2014 and December 2018 at five European centers. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2020.06.015DOI Listing

Corrected QT interval in Severe Aortic Stenosis: Clinical and Hemodynamic Correlates and Prognostic Impact.

Am J Med 2020 Jul 1. Epub 2020 Jul 1.

Cardiology Division, Kantonsspital St. Gallen, Switzerland. Electronic address:

Background: The role of the ECG for risk stratification in patients with severe aortic stenosis is not established. We assessed the hemodynamic correlates and the prognostic value of the corrected QT interval (QTc) in patients with severe AS undergoing aortic valve replacement.

Methods: The QT interval was measured in a 12-lead ECG in 485 patients (age 74±10 years, 57% males) with severe aortic stenosis [indexed aortic valve area 0. Read More

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http://dx.doi.org/10.1016/j.amjmed.2020.05.035DOI Listing

Feasibility of the transcatheter mitral valve repair for patients with severe mitral regurgitation and endangered heart failure.

J Formos Med Assoc 2020 Jun 30. Epub 2020 Jun 30.

Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Public Health, National Yang-Ming University, Taipei, Taiwan.

Background: The transcatheter edge-to-edge mitral valve repair using MitraClip has been a safe and effective treatment for severe mitral regurgitation (MR). In patients with severe MR and cardiogenic shock under hemodynamic supporting devices, emergent surgical mitral valve interventions carry extremely high risk for peri-operative morbidities and mortalities. The feasibility and efficacy of emergent MitraClip to rescue patients in critical conditions remains elucidate. Read More

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http://dx.doi.org/10.1016/j.jfma.2020.04.035DOI Listing

Unicuspid Aortic Valve Repair using Geometric Ring Annuloplasty.

Ann Thorac Surg 2020 Jun 30. Epub 2020 Jun 30.

Duke University, Durham, NC.

Background: Unicuspid aortic valves (UAV; Sievers Type 2 bicuspid) are characterized by major fusion/clefting of the right/left (R-L) coronary commissure, and minor fusion of the right/non (R-N) commissure. Repair has been difficult because of two fusions, variable relative sinus sizes, and peripheral leaflet deficiencies or tears after balloon valvuloplasty.

Methods: Twenty UAV patients underwent valve repair in 9 institutions. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.147DOI Listing

The Effects of Transcatheter Aortic Valve Replacement on Mitral Valve Function.

Cardiol Rev 2020 Jun 18. Epub 2020 Jun 18.

Department of Medicine New York Medical College/Westchester Medical Center, Valhalla, NY 10595.

The transcatheter aortic valve replacement (TAVR) procedure provides a way to treat severe aortic stenosis in the large population of patients who are not candidates for surgical aortic valve replacement (SAVR). Mitral regurgitation is often concomitant to aortic stenosis in these patients due to the high pressure of the left ventricle and long-term damage to the mitral valve. Due to the proximity of the aortic valve to the mitral valve, TAVR can impact the functional status of the mitral valve by affecting left ventricular outlet obstruction and the mitral valve annular shape. Read More

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http://dx.doi.org/10.1097/CRD.0000000000000315DOI Listing

Off-pump ascending aorta or aortic arch to descending aorta bypass with a pericardial roll for the treatment of critically ill infants with interrupted aortic arch.

Cardiol Young 2020 Jun 18:1-8. Epub 2020 Jun 18.

Department of Cardiovascular Surgery, Istanbul Medipol University Medical Faculty, Istanbul, Turkey.

Aim: Standard surgical treatment of the interrupted aortic arch with the use of cardiopulmonary bypass is risky especially in critically ill babies. In this manuscript, we present the results of off-pump pericardial roll bypass for the treatment of aortic interruption.

Material And Methods: The technique was applied in nine critically ill infants between July 2011 and December 2019. Read More

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http://dx.doi.org/10.1017/S1047951120001687DOI Listing

Transcatheter aortic valve replacement for bicuspid aortic valve regurgitation in a 17-year-old patient with congenitally corrected transposition of great arteries: a case report.

Eur Heart J Case Rep 2020 Jun 8;4(3):1-6. Epub 2020 May 8.

Smidt Heart Institute, Cedars Sinai Medical Center, 127 S. San Vicente Blvd, Third Floor, Suite A3600, Los Angeles, CA 90048, USA.

Background: Limited research has been conducted on the surgical management of the aortic valve in congenitally corrected transposition of great arteries (ccTGA) and to our knowledge there have been no reports on the treatment of bicuspid aortic regurgitation (AR) in ccTGA. We report on a ccTGA patient with bicuspid AR and systemic right ventricule (SRV) dysfunction who underwent transcatheter aortic valve replacement (TAVR).

Case Summary: A 17-year-old male with a history of ccTGA and cerebral palsy diagnosed at birth presented with heart failure. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319830PMC

'Minimalist approach' for transcatheter mitral valve replacement using intracardiac echocardiography and conscious sedation: a case series.

Eur Heart J Case Rep 2020 Jun 24;4(3):1-5. Epub 2020 Apr 24.

Department of Cardiology, Heart & Vascular Institute, Cleveland Clinic Florida, 2590 Cleveland Clinic Blvd, Weston, FL 33331, USA.

Background: Transcatheter aortic valve implantation operators have adapted to a less invasive technique by foregoing the use of general anaesthesia and transoesophageal echocardiography. This is known as a 'minimalist approach'. This approach has yet to be explored in transcatheter mitral valve replacement (TMVR). Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319820PMC

A case report: a rare case of severe aortic incompetence.

Eur Heart J Case Rep 2020 Jun 26;4(3):1-5. Epub 2020 May 26.

Hero DMC (Dayanand Medical College) Heart Institute, Civil Lines, DMC Road, Tagore Nagar, Ludhiana, Punjab 141001, India.

Background: Aneurysms of the sinus of Valsalva (SOV) are thin-walled outpouchings most commonly involving the right or non-coronary sinuses. Because they are asymptomatic, they are rarely discovered before they rupture and form an aorto-cardiac fistula. We present a rare case of unruptured aneurysm of the right coronary SOV burrowing into the interventricular septum with severe aortic incompetence and left ventricular dysfunction. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319804PMC

Early and Intermediate-Term Outcome of Balloon Aortic Valvuloplasty in Children With Aortic Stenosis and Left Ventricular Dysfunction at Tertiary Care Hospital.

Cureus 2020 May 27;12(5):e8321. Epub 2020 May 27.

Paediatric Cardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Background Left ventricular (LV) dysfunction in patients with aortic valve stenosis (AVS) is seen in two scenarios: in neonates and in elderly patients. Neonatal AVS may present as a congestive cardiac failure (CCF), while older children rarely present with CCF if they have not been diagnosed early. Only a few reports of LV dysfunction with AVS have been described in the literature. Read More

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http://dx.doi.org/10.7759/cureus.8321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325342PMC

Predictors of Contrast Volume in Transcatheter Aortic Valve Replacement.

Cardiology 2020 Jul 2:1-3. Epub 2020 Jul 2.

Division of Cardiovascular Medicine, Warren Alpert Medical School of Brown University and Lifespan Cardiovascular Institute, Providence, Rhode Island, USA.

Background: Contrast-induced acute kidney injury (CIAKI) is a frequent and serious complication of transcatheter aortic valve replacement (TAVR). The most important procedural risk factor for CIAKI is contrast volume.

Objectives: Because contrast volume is a modifiable factor that directly predicts CIAKI, we sought to identify predictors of increased contrast volume in TAVR patients. Read More

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http://dx.doi.org/10.1159/000507506DOI Listing

Outcomes and predictors of cardiac events in medically treated patients with atrial functional mitral regurgitation.

Int J Cardiol 2020 Jun 28. Epub 2020 Jun 28.

Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.

Background: Little is known about the outcomes and predictors of adverse cardiac events in medically treated patients with atrial functional mitral regurgitation (FMR).

Methods: We screened 1405 consecutive patients with grade ≥ 3+ mitral regurgitation (MR) detected by echocardiography. After excluding patients with previous or early (within 3 months from diagnosis) mitral valve surgery, congenital heart disease, hypertrophic cardiomyopathy, severe aortic valve disease, or unknown etiology, the study population consisted of 319 patients with primary MR, 395 patients with FMR with left ventricular (LV) dysfunction, and 184 patients with atrial FMR. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.06.042DOI Listing

Feasibility and safety of a fully percutaneous transcatheter aortic valve replacement program.

Catheter Cardiovasc Interv 2020 Jul 1. Epub 2020 Jul 1.

The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Objectives: This study aimed to assess the feasibility and safety of conducting an entire transcatheter aortic valve replacement (TAVR) program by using percutaneous techniques only.

Background: Surgically assisted transthoracic TAVR has been reported to be associated with more complications and longer hospital stays.

Methods: During 2019, all TAVR at a single center were performed by standard transfemoral (TF), intravascular lithotripsy-assisted TF, transaxillary (TAx), or transcaval approach using percutaneous techniques only. Read More

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http://dx.doi.org/10.1002/ccd.29117DOI Listing

An unusual presentation of developmental anomalies of the cardiovascular system including tetralogy of fallot, double outlet right ventricle, patent foramen ovale and persistent right aortic arch in a Friesian calf.

BMC Vet Res 2020 Jun 30;16(1):224. Epub 2020 Jun 30.

Section of Herd Health and Animal Husbandry, School of Veterinary Medicine, Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.

Background: Congenital heart diseases are occasionally encountered in the bovine species. Ventricular septal defects (VSD) and atrial septal defects (ASD) are reported to be the most common; however, a vast collection have been reported [1, 2]. Congenital heart diseases is thought to represent less than 3% of all congenital abnormalities in calves [3]. Read More

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http://dx.doi.org/10.1186/s12917-020-02439-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325375PMC

Histologic Abnormalities of the Ascending Aorta: Effects on Aortic Remodeling after Intracardiac Repair of Tetralogy of Fallot.

Tex Heart Inst J 2020 Apr;47(2):86-95

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi 110029, India.

We evaluated aortic tissue specimens from patients undergoing tetralogy of Fallot repair, to determine whether histologic abnormalities affect postsurgical aortic remodeling and other patient-related variables. Using light microscopy, we studied full-thickness aortic wall tissue operatively excised from 118 consecutive patients undergoing intracardiac repair of tetralogy of Fallot. We performed multiple linear regression analysis to identify independent predictors of change in aortic root dimensions, which we measured with echocardiography after repair and every 3 months thereafter. Read More

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http://dx.doi.org/10.14503/THIJ-17-6279DOI Listing

Transthoracic echocardiography and cardiac biomarkers in healthy captive male and female squirrel monkeys (Saimiri spp.).

BMC Vet Res 2020 Jun 29;16(1):217. Epub 2020 Jun 29.

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Background: Echocardiography is the most frequently used non -invasive diagnostic tool to evaluate cardiac anatomy and function in domestic species but increasingly also in non -domestic species, especially since cardiac disease is being recognized as an important cause of death in captive primates. The purpose of this cross -sectional study was to investigate the feasibility of transthoracic echocardiography in healthy squirrel monkeys as well as to provide species specific normal values for standard echocardiographic measurements. A secondary aim was to determine plasma and serum levels of the cardiac biomarkers, N -terminal pro -brain natriuretic peptide (NT -proBNP) and cardiac troponin T (cTnT). Read More

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http://dx.doi.org/10.1186/s12917-020-02406-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322930PMC

Determinants and Impact of Heart Failure Readmission Following Transcatheter Aortic Valve Replacement.

Circ Cardiovasc Interv 2020 Jul;13(7):e008959

Université de Rennes 1, CHU Rennes Service de Cardiologie, Inserm LTSI U1099, F 35000 Rennes, France (V.A., A.B., G.L., M.B., E.D., E.G., A.L., S.S., M.L.G., D.B., H.L.B.).

Background: Heart failure (HF) readmission is common post-transcatheter aortic valve replacement (TAVR). Nonetheless, limited data are available regarding its predictors and clinical impact. This study evaluated the incidence, predictors, and impact of HF readmission within 1-year post-TAVR, and assessed the effects of the prescription of HF therapies at discharge on the risk of HF readmission and death. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.120.008959DOI Listing

Bicuspid Aortic Valve Repair: Causes of Valve Failure and Long Term Outcomes.

Ann Thorac Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester.

Background: Repair of bicuspid aortic valves (BAV) for aortic regurgitation (AR) has favorable outcomes, but the impact of natural disease progression on durability of repair is uncertain. We evaluated causes of reoperation and compared outcomes of BAV repair to those of patients undergoing aortic valve replacement (AVR).

Methods: Between January 1993 and December 2016, 113 patients had bicuspid aortic valve repair at our institution for significant AR. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.146DOI Listing

Sex differences in bicuspid aortic valve disease.

Prog Cardiovasc Dis 2020 Jun 26. Epub 2020 Jun 26.

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Bicuspid aortic valve (BAV), the most frequent congenital heart disease, is characterized by an uneven distribution between sexes. BAV is three to four times more frequent in men than in women which could be associated with a reduced dosage of X chromosome genes. In addition, BAV has a multifactorial inheritance, low penetrance and variable phenotypes that may lead to different form of valve degeneration and dysfunction over time as well as different incidence of aortic valve and vascular complications between men and women. Read More

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http://dx.doi.org/10.1016/j.pcad.2020.06.004DOI Listing

How valvular calcification can affect the outcomes of transcatheter aortic valve implantation.

Expert Rev Med Devices 2020 Jun 29. Epub 2020 Jun 29.

Department of Cardiology, Leiden University Medical Center , Leiden, The Netherlands.

Introduction: In transcatheter aortic valve implantation (TAVI), assessment of aortic valve calcification is not as standardized as aortic annulus measurement. Aortic valve calcification is important for stable anchoring of the prosthesis to the aortic annulus. However, excessive aortic valve calcification is related to procedural complications. Read More

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http://dx.doi.org/10.1080/17434440.2020.1789456DOI Listing

Causes, Diagnosis, Risk Stratification and Treatment of Bicuspid Aortic Valve Disease: An Updated Review.

Cardiol Res 2020 Aug 3;11(4):205-212. Epub 2020 Jun 3.

Cardiology Department, Nicosia General Hospital, 2029, Nicosia, Cyprus.

The most common congenital heart disease is the bicuspid aortic valve. Understanding the pathophysiology and the altered hemodynamics is a key component for the diagnosis, risk stratification and treatment. Among others, aortic valve stenosis is the most common complication. Read More

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http://dx.doi.org/10.14740/cr1061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295561PMC

Echocardiographic diagnosis and follow-up for ALCAPA syndrome treated with the Takeuchi procedure.

Echocardiography 2020 Jun 28. Epub 2020 Jun 28.

Echocardiography Laboratory, National Institute of Cardiology of Mexico, "Ignacio Chávez", México City, México.

We present the case of an 18-year-old man with aborted sudden cardiac death. His initial echocardiogram suggested an anomalous origin of the left coronary artery from the pulmonary artery. Diagnosis was confirmed with coronary angiography. Read More

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http://dx.doi.org/10.1111/echo.14778DOI Listing

Prosthesis-patient mismatch after surgical aortic valve replacement in patients with aortic stenosis.

Interact Cardiovasc Thorac Surg 2020 Jun 24. Epub 2020 Jun 24.

Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objectives: The issue of prosthesis-patient mismatch (PPM) after surgical aortic valve replacement (SAVR) has been a controversial topic. We sought to evaluate the long-term clinical impacts of PPM in patients undergoing SAVR in an updated, homogeneous cohort.

Methods: Using the prospective institutional database, we identified 895 adult patients (median age 66, interquartile range 58-72; 45. Read More

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http://dx.doi.org/10.1093/icvts/ivaa085DOI Listing

Poor Survival with Impaired Valvular Hemodynamics After Aortic Valve Replacement: The National Echo Database Australia Study.

J Am Soc Echocardiogr 2020 Jun 24. Epub 2020 Jun 24.

School of Medicine, University of Notre Dame, Fremantle, Australia.

Background: There are limited data to describe the relationship between the transvalvular gradient and mortality among patients who undergo aortic valve replacement.

Methods: Using the National Echo Database Australia, valvular hemodynamics were characterized in 3,943 men (mean age, 62 ± 18 years) and 2,107 women (mean age, 62 ± 19 years) who underwent aortic valve replacement (median follow-up duration, 770 days; interquartile range, 381-1,584 days). The degree of impaired valvular hemodynamics (IVH) was categorized as mild (mean gradient 10. Read More

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http://dx.doi.org/10.1016/j.echo.2020.04.024DOI Listing

Classification of heart sound signals using a novel deep WaveNet model.

Comput Methods Programs Biomed 2020 Jun 12;196:105604. Epub 2020 Jun 12.

School of Engineering, Ngee Ann Polytechnic, 535 Clementi Road, Singapore 599489, Singapore; International Research Organization for Advanced Science and Technology (IROAST), Kumamoto University, Kumamoto, Japan; Department Bioinformatics and Medical Engineering, Asia University, Taiwan. Electronic address:

Background And Objectives: The high mortality rate and increasing prevalence of heart valve diseases globally warrant the need for rapid and accurate diagnosis of such diseases. Phonocardiogram (PCG) signals are used in this study due to the low cost of obtaining the signals. This study classifies five types of heart sounds, namely normal, aortic stenosis, mitral valve prolapse, mitral stenosis, and mitral regurgitation. Read More

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http://dx.doi.org/10.1016/j.cmpb.2020.105604DOI Listing

Safety and outcomes of combined liver transplantation and cardiac surgery in cirrhosis.

Ann Thorac Surg 2020 Jun 22. Epub 2020 Jun 22.

Departments of Gastroenterology/Transplant Hepatology, Cleveland Clinic, Ohio. Electronic address:

Background: Decompensation of the liver function after cardiac surgery in patients with cirrhosis has resulted high morbidity and mortality. A treatment strategy, of which there is a scarcity of data in the literature, encompasses combined liver transplant (LT) and cardiac surgery.

Methods: We performed a retrospective analysis of prospectively collected data on 15 patients who underwent combined LT and cardiac surgery between 2005 to 2017 at our institution. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.135DOI Listing

Impact of Chronic Kidney Disease on Outcomes in Transcatheter Aortic Valve Implantation.

Ann Acad Med Singapore 2020 May;49(5):273-284

Department of Cardiology, National Heart Centre Singapore, Singapore.

Introduction: Chronic kidney disease (CKD) is a significant comorbidity in aortic stenosis (AS) patients. We examined the impact of baseline CKD, postoperative acute kidney injury (AKI) and CKD progression on clinical outcomes in patients who underwent transcatheter aortic valve implantation (TAVI).

Materials And Methods: Consecutive patients with severe AS who underwent TAVI were classified into CKD stages 1-2 (≥60 mL/min/1. Read More

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May 2020
1.221 Impact Factor

Aortic root surgery; …sparing the valve.

Eur J Cardiothorac Surg 2020 Jun 23. Epub 2020 Jun 23.

Cardiac Surgery Department, Ippokrateio General Hospital of Athens, Athens, Greece.

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http://dx.doi.org/10.1093/ejcts/ezaa167DOI Listing

Device profile of the AltaValve system for transcatheter mitral valve replacement: overview of its safety and efficacy.

Expert Rev Med Devices 2020 Jun 25:1-10. Epub 2020 Jun 25.

Quebec Heart and Lung Institute, Laval University , Quebec City, Canada.

Introduction: In patients with severe mitral regurgitation (MR), transcatheter mitral valve replacement (TMVR) has recently emerged as an alternative to surgery. However, compared with transcatheter aortic valve replacement, TMVR faces several technical challenges and a high screening failure rate, mainly due to a more complex mitral annulus geometry and the potential interaction with the sub-valvular apparatus and the left ventricular outflow tract (LVOT). The AltaValve system is a device intended for TMVR with unique design features that may overcome most anatomical limitations for this therapy. Read More

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http://dx.doi.org/10.1080/17434440.2020.1781616DOI Listing

Pathophysiology of the aortic regurgitation Doppler signal end-diastolic notching: "A-dip insight".

Echocardiography 2020 Jun 20. Epub 2020 Jun 20.

Cardiology Department, Geneva University Hospital, Geneva, Switzerland.

A 76-year-old man was admitted to the hospital with symptoms of severe decompensated heart failure. Initial echocardiogram showed normal left ventricular (LV) ejection fraction, grade II diastolic dysfunction, and mild-to-moderate aortic regurgitation. The aortic regurgitant Doppler signal exhibited an end-diastolic notching, called an A-dip. Read More

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http://dx.doi.org/10.1111/echo.14774DOI Listing

Disorders of the Aorta and Aortic Valve in Connective Tissue Diseases.

Curr Cardiol Rep 2020 Jun 19;22(8):70. Epub 2020 Jun 19.

Department of Rheumatology and Internal Diseases, Poznan University of Medical Sciences, Poznan, Poland.

Purpose Of Review: The incidence of aortic valve disease in inherited connective tissue disorders is well documented; however, recent studies have only begun to unravel the pathology behind this association. In this review, we aim to describe the etiology, clinical manifestations, management, and prognosis of aortic and aortic valvular disorders that co-exist in a variety of connective tissue diseases. An extensive literature review was performed in PubMed. Read More

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http://dx.doi.org/10.1007/s11886-020-01314-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305067PMC

Aortic insufficiency associated with Impella that required surgical intervention upon implantation of the durable left ventricular assist device.

J Artif Organs 2020 Jun 19. Epub 2020 Jun 19.

Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

The Impella is an axial-flow percutaneous ventricular assist device for cardiogenic shock. In this report, we describe two patients who developed aortic insufficiency (AI) associated with Impella and required surgical intervention upon implantation of the durable left ventricular assist device (LVAD). Both patients presented with cardiogenic shock and underwent insertion of Impella 5. Read More

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http://dx.doi.org/10.1007/s10047-020-01184-xDOI Listing

Adaptive development of concomitant secondary mitral and tricuspid regurgitation after transcatheter aortic valve replacement.

Eur Heart J Cardiovasc Imaging 2020 Jun 20. Epub 2020 Jun 20.

Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

Aims: Concomitant secondary atrioventricular regurgitation is frequent in patients with severe aortic stenosis scheduled for transcatheter aortic valve replacement (TAVR). The future implications of leaving associated valve lesions untreated after TAVR remain unknown. Aim of the present study was to characterize the evolution of concomitant secondary atrioventricular regurgitations and to evaluate their impact on long-term prognosis. Read More

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http://dx.doi.org/10.1093/ehjci/jeaa106DOI Listing

New guidelines for diagnosis of rheumatic fever; do they apply to all populations?

Turk J Pediatr 2020 ;62(3):411-423

Department of Critical Care, Faculty of Medicine, Cairo University, Cairo, Egypt.

Background And Objectives: To evaluate the efficacy of recently updated Jones criteria for diagnosis of rheumatic fever in high incidence populations like Egypt.

Methods: Clinical data of 891 Egyptian patients with rheumatic fever, aged 5-15 years in a highly specialized rheumatic fever clinic were reviewed retrospectively from March 2014 to March 2016. Discriminant analysis was used to detect the most effective predictors for diagnosis of rheumatic fever in our patients incorporating echocardiographic criteria. Read More

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http://dx.doi.org/10.24953/turkjped.2020.03.008DOI Listing
January 2020

Asymptomatic chronic traumatic aortic valve perforation with severe aortic regurgitation.

Echocardiography 2020 Jun 17. Epub 2020 Jun 17.

Department of Cardiology, Holy Family Hospital and Medical Research Centre, Mumbai, India.

Here, we present a young asymptomatic male patient incidentally diagnosed to have aortic regurgitation (AR). The patient had a history of a blunt trauma to the thorax two years back but did never have any symptoms. Transthoracic echocardiography showed a moderately dilated left ventricle with normal systolic function and severe AR with normal nondilated aortic root and tri-leaflet aortic valve. Read More

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http://dx.doi.org/10.1111/echo.14758DOI Listing
June 2020
1.254 Impact Factor

Simultaneous aortic valve endocarditis and mycotic pseudoaneurysm of aortic coarctation.

J Card Surg 2020 Jun 19. Epub 2020 Jun 19.

Division of Thoracic and Cardiovascular Surgery, College of Medicine, University of Florida, Gainesville, Florida.

Objective: This study highlights the management strategy in simultaneous bicuspid aortic valve infective endocarditis and mycotic pseudoaneurysm of an aortic coarctation.

Methods: A staged repair of mycotic pseudoaneurysm of aortic coarctation and infective bicuspid aortic valve endocarditis.

Results: We present a 19-year old gentleman who was admitted with aching pain in his bilateral lower extremities with associated purpuric rash and fevers. Read More

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http://dx.doi.org/10.1111/jocs.14645DOI Listing

Vascular Complications in the Era of Transcatheter Treatment of Adult Structural Heart Disease: A Single-Center Early Experience.

Vasc Endovascular Surg 2020 Jun 19:1538574420934620. Epub 2020 Jun 19.

Division of Vascular & Endovascular Surgery, Department of Surgery, American University of Beirut Medical Centre, Beirut, Lebanon.

Transcatheter treatment is becoming the mainstay treatment for structural heart diseases (SHD) in prohibitive surgical risk patients. Recently with the encouraging results, it is being offered to regular risk patients. Peripheral vascular complications (VCs) are still inherent to these procedures due to the nature of this atherosclerotic high-risk group and the profile of the devices. Read More

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http://dx.doi.org/10.1177/1538574420934620DOI Listing

Transthoracic closure of ventricular septal defects guided by transesophageal echocardiography.

Turk Gogus Kalp Damar Cerrahisi Derg 2019 Jun 22;28(2):250-256. Epub 2020 Apr 22.

Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China.

Background: This study aims to investigate the effectiveness and safety of transthoracic closure of ventricular septal defects totally guided by transesophageal echocardiography.

Methods: A total of 119 patients (62 males, 57 females; mean age 2.1±5. Read More

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http://dx.doi.org/10.5606/tgkdc.dergisi.2020.18745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298365PMC

Immediate Outcomes of Aortic Valve Neocuspidization with Glutaraldehyde-treated Autologous Pericardium: a Multicenter Study.

Braz J Cardiovasc Surg 2020 Jun 1;35(3):241-248. Epub 2020 Jun 1.

University Duisburg-Essen University Hospital of Essen West German Heart and Vascular Center Essen Essen Germany Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.

Objective: To determine the feasibility of aortic valve neocuspidization (AVNeo) with glutaraldehyde-treated autologous pericardium.

Methods: One hundred and seventy (170) AVNeo (84 males/86 females) were performed from January 2017 through March 2019 in three centers. All the records were prospectively collected and retrospectively reviewed. Read More

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http://dx.doi.org/10.21470/1678-9741-2020-0019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299575PMC

Pulmonary hypertension due to left heart disease: diagnostic value of pulmonary artery distensibility.

Eur Radiol 2020 Jun 16. Epub 2020 Jun 16.

Division of Radiology, Cliniques Universitaires Saint-Luc, Université catholique de Louvain (UCL), Avenue Hippocrate 10, 1200, Brussels, Belgium.

Objectives: To evaluate how pulmonary artery (PA) distensibility performs in detecting pulmonary hypertension due to left heart disease (PH-LHD) in comparison with parameters from ungated computed tomography (CT) and echocardiography.

Methods: One hundred patients (79 men, mean age = 63 ± 17 years) with either severe heart failure with reduced ejection fraction (HFrEF), aortic stenosis, or primary mitral regurgitation prospectively underwent right heart catheterization, ungated CT, ECG-gated CT, and echocardiography. During the ECG-gated CT, the right PA distensibility was calculated. Read More

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http://dx.doi.org/10.1007/s00330-020-06959-7DOI Listing

Early results of the ongoing Polish Registry on Valve Thrombosis after Transcatheter Aortic Valve Implantation (ZAK-POL TAVI).

Kardiol Pol 2020 06 8. Epub 2020 Jun 8.

Background: Conflicting data exist regarding the risk factors of transcatheter valve thrombosis (THVT). In addition, the best pharmacological strategy to treat THVT is still unknown.

Aims: The aim was to assess the incidence, risk factors, diagnostic work-up and treatment of THVT in Poland. Read More

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http://dx.doi.org/10.33963/KP.15426DOI Listing

Aortic regurgitation resulted from traumatic leaflet tear due to calcified amorphous tumour.

Eur Heart J Cardiovasc Imaging 2020 Jun 15. Epub 2020 Jun 15.

Department of Cardiovascular Surgery, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

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http://dx.doi.org/10.1093/ehjci/jeaa124DOI Listing

Excellent hemodynamic performance after aortic valve neocuspidization (AVNeo) using autologous pericardium.

Ann Thorac Surg 2020 Jun 12. Epub 2020 Jun 12.

Department of Cardiovascular Surgery, German Heart Center Munich, Technical University Munich, Munich, Germany,; Insure (Institute for Translational Cardiac Surgery), Department of Cardiovascular Surgery, German Heart Center, Technical University Munich, Munich, Germany,; DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.

Background: Aortic valve neocuspidization (AVNeo) for trileaflet aortic valve reconstruction using autologous pericardium (Ozaki procedure) offers an alternative treatment modality to overcome drawbacks of conventional prosthetic aortic valve replacement.

Methods: 103 patients were operated between 10/2016 and 04/2019. Mean follow up was 426days±270. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.108DOI Listing

Artificial Intelligence for Dynamic Echocardiographic Tricuspid Valve Analysis: A New Tool in Echocardiography.

J Cardiothorac Vasc Anesth 2020 May 15. Epub 2020 May 15.

Department of Surgery, Division of Cardiac Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address:

There has been a resurgence of interest in the structure and function of the tricuspid valve (TV) with the established prognostic impact of functional tricuspid regurgitation. Current 3-dimensional transesophageal echocardiography prototype software is limited to exploration of the mitral and aortic valves exclusively. Thus, newer analytical software is required for dynamic geometric analysis of the TV morphology for remodeling. Read More

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http://dx.doi.org/10.1053/j.jvca.2020.04.056DOI Listing

Dynamic changes of mitral annulus in patients with degenerative mitral regurgitation and chronic atrial fibrillation undergoing mitral valve reconstruction.

Gen Thorac Cardiovasc Surg 2020 Jun 14. Epub 2020 Jun 14.

Division of Cardiovascular Surgery, Shiga University of Medical Science, Setatsukinowa, Otsu, 520-2192, Japan.

Objective: This study was designed to assess structural and dynamic changes in the mitral annulus in patients before mitral valve reconstruction for degenerative mitral regurgitation with or without chronic atrial fibrillation.

Methods: One hundred and fifty one consecutive patients undergoing mitral valve reconstruction for mitral regurgitation due to myxomatous disease between July 2013 and May 2016 were included. Of these, 117 had a sinus rhythm (SR group) and 34 had chronic AF (AF group). Read More

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http://dx.doi.org/10.1007/s11748-020-01406-2DOI Listing

Evaluation of aortic stenosis using cardiovascular magnetic resonance: a systematic review & meta-analysis.

J Cardiovasc Magn Reson 2020 06 15;22(1):45. Epub 2020 Jun 15.

Sydney Translational Imaging Laboratory, Imaging and Phenotyping Laboratory, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia.

Background: As the average age of patients with severe aortic stenosis (AS) who receive procedural intervention continue to age, the need for non-invasive modalities that provide accurate diagnosis and operative planning is increasingly important. Advances in cardiovascular magnetic resonance (CMR) over the past two decades mean it is able to provide haemodynamic data at the aortic valve, along with high fidelity anatomical imaging.

Methods: Electronic databases were searched for studies comparing CMR to transthoracic echocardiography (TTE) and transoesophageal echocardiography (TEE) in the diagnosis of AS. Read More

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http://dx.doi.org/10.1186/s12968-020-00633-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294634PMC

Aortic root morphology can cause early bioprosthetic valve failure of externally mounted pericardial bioprosthesis.

Gen Thorac Cardiovasc Surg 2020 Jun 13. Epub 2020 Jun 13.

Department of Cardiovascular Surgery, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

A 73-year-old woman with a narrow aortic root had undergone aortic valve replacement with a 19-mm Mitroflow valve. Aortic annular enlargement with Manouguian's technique was performed, and the bioprosthesis had been implanted on the tilt in a supra-annular position. Four years after the implantation, echocardiography showed a significant de novo aortic regurgitation, which had not been detected 1 year earlier. Read More

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http://dx.doi.org/10.1007/s11748-020-01402-6DOI Listing

Aortic Valve Deformation During Transcatheter Mitral Valve Replacement.

JACC Cardiovasc Interv 2020 Jun 6. Epub 2020 Jun 6.

Department of Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1016/j.jcin.2020.03.033DOI Listing