24,498 results match your criteria Aortic Regurgitation


Aortic root changes before and after surgery for chronic aortic dilatation: A 3D Echocardiographic study.

Echocardiography 2018 Dec 16. Epub 2018 Dec 16.

Division of Cardiology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Background: Quantitative 3D assessment of the aortic root may improve planning and success of aortic valve (AV)-sparing operations.

Aims: To use 3D transesophageal echocardiography (TEE) to assess the effect of chronic aortic dilatation on aortic root shape and aortic regurgitation (AR) severity and to examine the effects of AV-sparing operations.

Methods And Results: To determine the changes with chronic aortic dilatation, we studied 48 patients, 23 with aortic dilatation (Group 1 ≤ mild AR, n = 13; Group 2 ≥ moderate AR, n = 10) and 25 Controls. Read More

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http://dx.doi.org/10.1111/echo.14216DOI Listing
December 2018

Profiles of hospitalized patients with valvular heart disease: Experience of a tertiary center.

Rev Port Cardiol 2018 Dec 13. Epub 2018 Dec 13.

Cardiology Department, Hospital de Santa Maria, CHLN, CCUL, Centro Académico de Medicina de Lisboa, Faculdade de Medicina da Universidade de Lisboa, Portugal.

Introduction: Valvular heart disease (VHD) is increasing worldwide, mostly because of aging. Percutaneous valve intervention is the preferred therapeutic option in high-risk patients.

Objective: To characterize the profiles of patients with VHD admitted to the cardiology ward at a tertiary referral center. Read More

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http://dx.doi.org/10.1016/j.repc.2018.02.012DOI Listing
December 2018

Pulmonary Hypertension and Aortic Stenosis: Further Evidence That TAVR Is Not SAVR.

JACC Cardiovasc Imaging 2018 Dec 6. Epub 2018 Dec 6.

Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina.

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https://linkinghub.elsevier.com/retrieve/pii/S1936878X183030
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http://dx.doi.org/10.1016/j.jcmg.2018.04.003DOI Listing
December 2018
1 Read

AVIATOR: An open international registry to evaluate medical and surgical outcomes of aortic valve insufficiency and ascending aorta aneurysm.

J Thorac Cardiovasc Surg 2018 Oct 26. Epub 2018 Oct 26.

Department of Cardiac Surgery, Institut Mutualiste Montsouris, Paris, France.

Objectives: Current national registries are lacking detailed pathology-driven analysis and long-term patients outcomes. The Heart Valve Society (HVS) aortic valve (AV) repair research network started the Aortic Valve Insufficiency and ascending aorta Aneurysm InternATiOnal Registry (AVIATOR) to evaluate long-term patient outcomes of AV repair and replacement. The purpose of the current report is to describe the AVIATOR initiative and report in a descriptive manner the patients included. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.10.076DOI Listing
October 2018

Quantification of rheumatic mitral stenosis severity with three-dimensional vena contracta area.

Echocardiography 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiology, Marmara University Medical Center, Istanbul, Turkey.

Introduction: Rheumatic mitral stenosis (MS) is an important health issue in developing countries. Assessment of the correct mitral valve area (MVA) is essential for the timing of intervention. Most of the parameters for the assessment of rheumatic MS are derived from Two-dimensional (2D) echocardiography. Read More

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http://dx.doi.org/10.1111/echo.14213DOI Listing
December 2018

Meta-Analysis Comparing the Incidence of Infective Endocarditis Following Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement.

Am J Cardiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine Division of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa, Iowa.

Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter valve prosthesis and native valves could dispose TAVI recipients at increased risk of IE compared with SAVR. To assess the comparative risk of IE between TAVI and SAVR, we performed a systematic review and meta-analysis. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.11.031DOI Listing
December 2018

Survey of owners on population characteristics, diagnosis, and environmental, health, and disease associations in dogs with megaesophagus.

Authors:
Jillian M Haines

Res Vet Sci 2018 Nov 30;123:1-6. Epub 2018 Nov 30.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, PO Box 647060, Pullman, WA 99164-7060, USA. Electronic address:

Megaesophagus affects dogs worldwide but limited information is available regarding its characteristics in the general population of dogs. The objectives of this study were to provide information on a large population of dogs diagnosed with megaesophagus in regards to population characteristics, medical and family history, diagnosis, concurrent disease, and predisposing factors. A link to a web-based survey was provided on megaesophagus support websites and 838 eligible surveys were evaluated. Read More

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http://dx.doi.org/10.1016/j.rvsc.2018.11.026DOI Listing
November 2018
1 Read

Early structural valve deterioration and reoperation associated with the mitroflow aortic valve.

J Card Surg 2018 Dec 7. Epub 2018 Dec 7.

Corrigan Minehan Heart Center and Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts.

Background: Structural valve deterioration (SVD) is a known limitation of bioprosthetic valves. Recent reports have suggested a concerning rate of early SVD in patients receiving a Mitroflow aortic bioprosthesis. We therefore compared the incidence of SVD and SVD requiring reoperation among patients receiving a Mitroflow versus a common contemporary bioprosthesis. Read More

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http://dx.doi.org/10.1111/jocs.13953DOI Listing
December 2018

Initial results from the off-label use of the SAPIEN S3 valve for percutaneous transcatheter pulmonary valve replacement: A multi-institutional experience.

Catheter Cardiovasc Interv 2018 Dec 7. Epub 2018 Dec 7.

Department of Pediatrics, Division of Cardiology, UCLA Mattel Children's Hospital, Los Angeles, California.

Objectives: To describe a multi-center experience of percutaneous transcatheter pulmonary valve replacement (TPVR) using the Edwards Sapien S3 Valve.

Background: Off-label use of the Sapien S3 valve can allow for TPVR in patients with congenital heart disease (CHD) and large diameter dysfunctional right ventricular outflow tract (RVOT). The initial experience at five centers with the SAPIEN S3 valve for TPVR is presented with a focus on procedural techniques, success, complications, and efficacy. Read More

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http://dx.doi.org/10.1002/ccd.27973DOI Listing
December 2018
1 Read

Severe aortic valve stenosis in a 14-year-old boy with sitosterolemia.

J Clin Lipidol 2018 Nov 14. Epub 2018 Nov 14.

Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

We report a 14-year-old boy finally diagnosed with sitosterolemia, presenting with severe aortic valve stenosis. Genetic analysis revealed homozygous null mutation c.1336 C > T (p. Read More

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http://dx.doi.org/10.1016/j.jacl.2018.11.002DOI Listing
November 2018

Comparison of Local Versus General Anesthesia Following Transfemoral Transcatheter Self-Expanding Aortic Valve Implantation (from the Transcatheter Valve Therapeutics Registry).

Am J Cardiol 2018 Nov 6. Epub 2018 Nov 6.

The Valve and Structural Heart Disease Center, Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Transfemoral transcatheter aortic valve replacement (TF-TAVR) is mostly performed under general anesthesia (GA) in most US centers. We examined in-hospital and 30-day outcomes in patients who underwent TF-TAVR with a self-expanding bioprosthesis using local anesthesia (LA) or GA. Patients from the Transcatheter Valve Therapeutics Registry who underwent TF-TAVR from January 2014 to June 2016 with LA or GA were evaluated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149183205
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http://dx.doi.org/10.1016/j.amjcard.2018.10.041DOI Listing
November 2018
2 Reads

Novel variants in the ACTA2 and MYH11 genes in a Cypriot family with thoracic aortic aneurysms: a case report.

BMC Med Genet 2018 Dec 7;19(1):208. Epub 2018 Dec 7.

Department of Cardiovascular Genetics and The Laboratory of Forensic Genetics, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

Background: Thoracic aortic aneurysm (TAA) and/or thoracic aortic aneurysm and dissection (TAAD) is characterized by a considerable risk of morbidity and mortality of affected individuals. It is inherited in an autosomal dominant pattern and the 20% of patients with non-syndromic TAA have a positive family history. To date, the genetic basis of Cypriot patients with TAA has not been investigated. Read More

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http://dx.doi.org/10.1186/s12881-018-0728-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286578PMC
December 2018

[Heart Valve Disease - update ESC guideline 2017].

Dtsch Med Wochenschr 2018 Dec 3;143(24):1765-1769. Epub 2018 Dec 3.

Klinik für Kardiologie, Pneumologie und Angiologie, Universitätsklinikum Düsseldorf, Düsseldorf.

Surgical management of patients with aortic valve stenosis is declining and Transcatheter aortic valve implantation (TAVI) is becoming the treatment of choice in many patients. The ESC guideline integrated results of randomized controlled trials in patients with intermediate surgical risk for the first time. TAVI showed good and comparable results to the standard surgical approach. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0601-1430
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http://dx.doi.org/10.1055/a-0601-1430DOI Listing
December 2018
3 Reads

Transcatheter aortic valve replacement in patients with bicuspid aortic valves.

J Thorac Dis 2018 Nov;10(Suppl 30):S3568-S3572

Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA.

Transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic aortic stenosis (AS) has rapidly become the standard of care for expanding clinical indications based on the results of multiple large-scale randomized trials. Patients with bicuspid aortic valve (BAV) have been largely excluded from these trials for a variety of reasons. However, case series and registry data has shown TAVR in BAV to be a safe and efficacious alternative to surgical aortic valve replacement (SAVR) with the possible caveats of increased paravalvular regurgitation (PVR) and need for permanent pacemaker (PPM) implantation. Read More

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http://dx.doi.org/10.21037/jtd.2018.07.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242917PMC
November 2018
1 Read

Simultaneously surgical management of adult complex coarctation of aorta concomitant with intracardiac abnormality.

J Thorac Dis 2018 Oct;10(10):5842-5849

Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Background: To explore surgical management of complex coarctation of aorta (COA) concomitant with intracardiac abnormality, in order to provide recommendations for safe and reliable treatment.

Methods: Totally, six adult cases demonstrating complex COA concomitant with intracardiac abnormality were reviewed from our department between May 2012 and June 2017. Four patients were male and two patients were female, the age range being 43. Read More

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http://dx.doi.org/10.21037/jtd.2018.09.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236160PMC
October 2018
1 Read

The CHOICE Between Self-Expanding and Balloon-Expandable Valves for Transcatheter Aortic Valve Replacement.

Authors:
Philippe Pibarot

JACC Cardiovasc Interv 2018 Nov 23. Epub 2018 Nov 23.

Institut Universitaire de Cardiologie et de Pneumologie de Québec/Québec Heart & Lung Institute, Department of Medicine, Laval University, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2018.10.003DOI Listing
November 2018

Bioprosthetic Valve Performance After Transcatheter Aortic Valve Replacement With Self-Expanding Versus Balloon-Expandable Valves in Large Versus Small Aortic Valve Annuli: Insights From the CHOICE Trial and the CHOICE-Extend Registry.

JACC Cardiovasc Interv 2018 Nov 23. Epub 2018 Nov 23.

The Heart Center, Segeberger Kliniken (Academic Teaching Hospital of the Universities of Kiel, Lübeck, and Hamburg), Bad Segeberg, Germany; Cardiology Department, Heart Center Leipzig - University Hospital, Leipzig, Germany.

Objectives: The aim of this study was to compare self-expanding and balloon-expandable transcatheter heart valves (THVs) in large versus small aortic valve annuli.

Background: The degree of THV oversizing varies according to annular size, and this can modify the hemodynamic performance of self-expanding and balloon-expandable THVs.

Methods: Patients undergoing transcatheter aortic valve replacement in the randomized CHOICE (Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: Medtronic CoreValve vs Edwards SAPIEN XT) trial (CoreValve [CV], n = 120; SAPIEN XT [SXT], n = 121) and the nonrandomized CHOICE-Extend registry (Evolut R [ER], n = 100; SAPIEN 3 [S3], n = 334) were compared for THV performance by echocardiography (in all patients) and by cardiac magnetic resonance imaging (MRI) regurgitant fraction (RF) (in a subgroup of patients). Read More

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http://dx.doi.org/10.1016/j.jcin.2018.07.050DOI Listing
November 2018
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Transcatheter Aortic Valve Replacement for Pure Native Aortic Valve Regurgitation: A Systematic Review.

Cardiology 2018 Dec 5;141(3):132-140. Epub 2018 Dec 5.

Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou,

Background: Transcatheter aortic valve replacement (TAVR) is a recent and an effective treatment option for high- or extreme-surgical-risk patients with symptomatic severe aortic stenosis. However, pure severe native aortic valve regurgitation (NAVR) without aortic stenosis remains a contraindication to TAVR. The aim of our systemic review analysis was to evaluate TAVR in patients with pure NAVR. Read More

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http://dx.doi.org/10.1159/000491919DOI Listing
December 2018
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Comment on "Transcatheter Aortic Valve Replacement in Patients with Pure Native Aortic Valve Regurgitation: A Systematic Review and Meta-analysis".

Clin Cardiol 2018 Dec 5. Epub 2018 Dec 5.

Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.

The timely publication by Haddad et al. entitled "Transcatheter Aortic Valve Replacement in Patients with Pure Native Aortic Valve Regurgitation: A Systematic Review and Meta-analysis" in the journal Clinical Cardiology addresses one of the topics which is receiving increasing attention in cardiovascular intervention field [1]. Read More

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http://dx.doi.org/10.1002/clc.23127DOI Listing
December 2018
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Impact of Tricuspid Regurgitation and Right Ventricular Dysfunction on Outcomes After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.

Clin Cardiol 2018 Dec 4. Epub 2018 Dec 4.

Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

Background: Far less attention has been paid to the prognostic effect of right-side heart disease on outcomes after transcatheter aortic valve replacement (TAVR) when compared with the left side. Therefore, we performed a systematic review and meta-analysis on the impact of tricuspid regurgitation (TR) and right ventricular (RV) dysfunction on outcomes after TAVR.

Hypothesis: We hypothesized that TR and RV dysfunction may have a deleterious effect on outcomes after TAVR. Read More

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http://dx.doi.org/10.1002/clc.23126DOI Listing
December 2018
1 Read

Aortic disease and interventions in adults with tetralogy of Fallot.

Heart 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Background: Aortic dilation and aortic valve disease are known long-term complication of tetralogy of Fallot (TOF), but the risk of aortic dissection and the indications for prophylactic aortic surgery are unknown in this population. The purpose of this study was to: (1) determine the prevalence of significant aortic valve disease and/or significant aortic aneurysm (AVD-AA); (2) determine the incidence of progressive aortic dilation and aortic dissection in patients with TOF.

Methods: Retrospective review of adults with repaired TOF, and no prior aortic valve/aorta surgery, who had ≥2 measurements of the thoracic aorta >12 months apart, 1990-2017. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314115DOI Listing
December 2018
1 Read

The Multivalvular Score for Predicting the Outcome of Mitral Regurgitation in Aortic Stenosis Patients Treated With TAVI: Prospective Validation.

Rev Esp Cardiol (Engl Ed) 2018 Dec 1. Epub 2018 Dec 1.

Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

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http://dx.doi.org/10.1016/j.rec.2018.10.007DOI Listing
December 2018
1 Read

[Transapical transcatheter aortic valve replacement for high risk pure non-calcified aortic regurgitation: two years outcome of a multi-center study].

Zhonghua Wai Ke Za Zhi 2018 Dec;56(12):910-915

Departments of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

To report on the two years outcome of Chinese multi-center study of the treatment of high risk non-calcified pure aortic regurgitation with transcatheter heart valve replacement (TAVR) using domestic made J-Valve™ system. The national multi-center clinical study of the treatment of high risk non-calcified pure aortic regurgitation with transcatheter heart valve replacement using domestic made J-Valve™ system was conducted during the period from April 2014 to July 2015. The follow-up time was up to 2 years. Read More

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December 2018
4 Reads

Predictors of Outcome for Aortic Valve Reimplantation Including the Surgeon-A Single-Center Experience.

Thorac Cardiovasc Surg 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, University Hospital Jena, Friedrich Schiller University Jena, Jena, Germany.

Introduction:  Aortic valve reimplantation is considered technically demanding. We searched for predictors of long-term outcome including the surgeon as risk factor.

Methods:  We selected all aortic valve reimplantations performed in our department between December 1999 and January 2017 and obtained a complete follow-up. Read More

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http://dx.doi.org/10.1055/s-0038-1675594DOI Listing
November 2018

Risk factors for paravalvular leak after transcatheter aortic valve replacement.

J Thorac Cardiovasc Surg 2018 Sep 27. Epub 2018 Sep 27.

Department of Cardiac Surgery, Cardiovascular Center, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.

Objective: To assess risk factors for paravalvular leak (PVL) after transcatheter aortic valve implantation in a large single-center cohort, including measurement of aortic valve calcification using a reproducible method.

Methods: We retrospectively analyzed preoperative contrast-enhanced multidetector computed tomography scans of patients who underwent transcatheter aortic valve implantation in our center between 2009 and 2016. Calcium volume was calculated for each aortic cusp in the aortic valve, left ventricular outflow tract, and device landing zone. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.08.085DOI Listing
September 2018

Transfemoral aortic valve replacement for severe aortic valve regurgitation in a patient with a pulsatile-flow biventricular assist device.

ESC Heart Fail 2018 Nov 27. Epub 2018 Nov 27.

Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany.

Severe aortic regurgitation (AR) is a rare but significant complication of ventricular assist device therapy. Experience with transcatheter aortic valve replacement (TAVR) in this setting of patients is very limited, while the scarcely reported cases exclusively refer to TAVR under continuous-flow left ventricular assist devices. Here, we present the first successful TAVR while running a pulsatile-flow biventricular assist device (PF-BiVAD). Read More

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http://dx.doi.org/10.1002/ehf2.12384DOI Listing
November 2018
1 Read

Impact of concurrent tricuspid regurgitation on mortality after transcatheter aortic-valve implantation.

Catheter Cardiovasc Interv 2018 Nov 25. Epub 2018 Nov 25.

Department of Cardiology, Detroit Medical Center, Detroit, Michigan.

Objectives: To determine whether concomitant tricuspid regurgitation (TR) is associated with increased mortality in patients with severe aortic stenosis (AS) undergoing transcatheter aortic-valve implantation (TAVI), we performed a meta-analysis of currently available studies.

Methods: MEDLINE and EMBASE were searched through May 2018. We included comparative or cohort studies enrolling patients with AS undergoing TAVI and reporting early (in-hospital or 30-day) and late (including early) all-cause mortality in patients stratified by baseline TR grade. Read More

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http://dx.doi.org/10.1002/ccd.27948DOI Listing
November 2018
1 Read

Color Doppler Artifact Masking Iatrogenic Aortic Valve Injury Related to an Impella Device.

J Cardiothorac Vasc Anesth 2018 Sep 27. Epub 2018 Sep 27.

Department of Anesthesiology and Perioperative Medicine, Tufts Medical Center, Boston, MA.

The Impella (Abiomed, Danvers, MA) is a minimally invasive transvalvular left ventricular assist device (LVAD) that effectively unloads the left ventricle (LV), especially in patients with ventricular arrhythmias in the setting of a venous-arterial extracorporeal membrane oxygenator (VA ECMO). Utilization of the Impella device has increased significantly in the last few years for high-risk percutaneous coronary intervention and cardiogenic shock because of its relatively easy implantation in the catheterization lab and the operating room. Although rare, iatrogenic injury of the aortic valve (AV) can be caused by placement of the device across the AV. Read More

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http://dx.doi.org/10.1053/j.jvca.2018.09.035DOI Listing
September 2018
8 Reads

The Latest Evolution of the Medtronic CoreValve System in the Era of Transcatheter Aortic Valve Replacement: Matched Comparison of the Evolut PRO and Evolut R.

JACC Cardiovasc Interv 2018 Nov;11(22):2314-2322

University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology and Vascular Medicine, Düsseldorf, Germany.

Objectives: The aim of this study was to investigate the hemodynamic and clinical performance of the Evolut PRO compared with its direct predecessor, the Evolut R.

Background: Recently, the newest commercially available generation of the self-expandable Medtronic CoreValve prosthesis, the CoreValve Evolut PRO, was introduced to the market. This prosthesis is based on the previous Evolut R model and specifically designed to mitigate paravalvular leakage. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.07.023DOI Listing
November 2018
8 Reads

Modified sizing technique with newly designed tools to facilitate the valve sparing aortic root replacement "David" procedure with mid-term results.

J Cardiovasc Surg (Torino) 2018 Nov 20. Epub 2018 Nov 20.

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Centre Essen, University Hospital Essen, Essen, Germany.

Background: Valve sparing root replacement differs in specific points. The main target remains to achieve a perfect intraoperative result and long-term stability. We aimed in this study to present our modified sizing technique for valve-sparing "David" procedure and its mid-term results. Read More

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http://dx.doi.org/10.23736/S0021-9509.18.10690-2DOI Listing
November 2018
3 Reads

Edwards Sapien 3 transcatheter aortic valve implantation for management of severe aortic regurgitation in a teenage patient with corrected atrioventricular septal defect and progressive left ventricular dysfunction.

Catheter Cardiovasc Interv 2018 Nov 20. Epub 2018 Nov 20.

Department of Pediatric Cardiology and Intensive Care, Munich University Hospital, Ludwig Maximilians University, Munich, Germany.

Transcatheter aortic valve replacement is mostly performed in elderly patients with severely calcified aortic valves. There are few reports about its use for pure aortic regurgitation, few reports about its use in adolescent patients and to the best of our knowledge no report about the use of an Edwards Sapien valve in the aortic position in an underage patient after surgically corrected congenital heart disease (CHD). Decompensation of a complex CHD can be difficult to manage and may require unusual solutions. Read More

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http://dx.doi.org/10.1002/ccd.27975DOI Listing
November 2018
6 Reads

Patient-specific simulation of transcatheter aortic valve replacement: impact of deployment options on paravalvular leakage.

Biomech Model Mechanobiol 2018 Nov 20. Epub 2018 Nov 20.

Department of Biomedical Engineering, Stony Brook University, T15-090 Health Sciences Center, Stony Brook, NY, 11794-8151, USA.

Transcatheter aortic valve replacement (TAVR) has emerged as an effective alternative to conventional surgical valve replacement in high-risk patients afflicted by severe aortic stenosis. Despite newer-generation devices enhancements, post-procedural complications such as paravalvular leakage (PVL) and related thromboembolic events have been hindering TAVR expansion into lower-risk patients. Computational methods can be used to build and simulate patient-specific deployment of transcatheter aortic valves (TAVs) and help predict the occurrence and degree of PVL. Read More

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http://dx.doi.org/10.1007/s10237-018-1094-8DOI Listing
November 2018
4 Reads

The Genetic Regulation of Aortic Valve Development and Calcific Disease.

Front Cardiovasc Med 2018 6;5:162. Epub 2018 Nov 6.

Center for Cardiovascular Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.

Heart valves are dynamic, highly organized structures required for unidirectional blood flow through the heart. Over an average lifetime, the valve leaflets or cusps open and close over a billion times, however in over 5 million Americans, leaflet function fails due to biomechanical insufficiency in response to wear-and-tear or pathological stimulus. Calcific aortic valve disease (CAVD) is the most common valve pathology and leads to stiffening of the cusp and narrowing of the aortic orifice leading to stenosis and insufficiency. Read More

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http://dx.doi.org/10.3389/fcvm.2018.00162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232166PMC
November 2018
2 Reads

Emergent valve-in-valve transcatheter aortic valve replacement in patient with acute aortic regurgitation and cardiogenic shock with preoperative extracorporeal membrane oxygenator: A case report and review of the literature.

Cardiovasc Revasc Med 2018 Dec 12;19(8S):68-70. Epub 2018 Nov 12.

Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America. Electronic address:

We describe a challenging case of successful use of emergent veno-arterial extracorporeal membrane oxygenation and valve-in-valve transcatheter aortic valve implantation with a Sapien S3 valve. Read More

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http://dx.doi.org/10.1016/j.carrev.2018.11.007DOI Listing
December 2018
1 Read

[Valve-sparing Aortic Root Replacement in Patient with Dissecting Ascending Aortic Aneurysm Complicated with Hemorrhagic Moyamoya Disease;Report of a Case].

Kyobu Geka 2018 Nov;71(12):1031-1034

Department of Cardiovascular Surgery, Japanese Red Cross Kochi Hospital, Kochi, Japan.

A 62-year-old female with Moyamoya disease (MMD) had cardiomegaly pointed out by chest X-ray and was admitted to our hospital. Chest computed tomography (CT) scan and echocardiography revealed a large dissecting ascending aortic aneurysm 78 mm in diameter combined with severe aortic regurgitation and mild mitral regurgitation. She had a history of intracranial hemorrhage related with MMD twice. Read More

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November 2018
3 Reads

[Aortic Root Pseudoaneurysm due to Avulsion of Aortic Valve Commissure Following to Infective Endocarditis;Report of a case].

Kyobu Geka 2018 Nov;71(12):1027-1030

Department of Cardiovascular Surgery, Japanese Red Cross Ishinomaki Hospital, Ishinomaki, Japan.

A 40-year-old man presented to our hospital with fever and slight palpitation. The echocardiogram revealed bicuspid aortic valve, massive aortic regurgitation, and aneurysm of Valsalva sinus. Operative findings showed an aortic root pseudoaneurysm originating just below the avulsion of the right to left commissure. Read More

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November 2018
6 Reads

Valvular Heart Disease and Heart Failure in Women.

Heart Fail Clin 2019 Jan;15(1):77-85

Division of Cardiology, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street Blake 256, Boston, MA 02114, USA. Electronic address:

Valvular heart disease and heart failure remain important causes of cardiovascular disease among women in the United States. Mitral regurgitation, aortic stenosis, and tricuspid regurgitation are the most common valvular lesions among men and women. This review focuses on gender differences in the epidemiology, treatment, and outcomes of mitral regurgitation, aortic stenosis, and tricuspid regurgitation. Read More

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http://dx.doi.org/10.1016/j.hfc.2018.08.008DOI Listing
January 2019
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Optimizing the Assessment of Aortic Regurgitation: The Importance of Quantity and Quality.

Authors:
Saul G Myerson

JACC Cardiovasc Imaging 2018 Nov 8. Epub 2018 Nov 8.

Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford Centre for Clinical Magnetic Resonance Research, John Radcliffe Hospital, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2018.09.016DOI Listing
November 2018
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Diagnostic and Prognostic Utility of Cardiac Magnetic Resonance Imaging in Aortic Regurgitation.

JACC Cardiovasc Imaging 2018 Nov 8. Epub 2018 Nov 8.

Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria. Electronic address:

Objectives: This study investigated the diagnostic and prognostic value of cardiac magnetic resonance (CMR) imaging in chronic aortic regurgitation (AR).

Background: Accurate quantification of AR severity by echocardiography frequently remains difficult. CMR is recommended as the complementary method; however, its accuracy and prognostic utility remain unknown. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1936878X183090
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http://dx.doi.org/10.1016/j.jcmg.2018.08.036DOI Listing
November 2018
5 Reads

Doppler-Echocardiographic Assessment of Tricuspid Regurgitation.

Prog Cardiovasc Dis 2018 Nov 14. Epub 2018 Nov 14.

The Division of Cardiology, Mayo College of Medicine, Mayo Clinic, Rochester, MN, United States of America.

Compared with the vast literature concerning the echocardiographic assessment of mitral, or aortic disease, the data concerning the evaluation of tricuspid regurgitation (TR) is very limited. In this review we summarized the present data concerning the assessment of TR. We review the present knowledge concerning the pathogenesis of TR showing that it is extremely multi-factorial, thus, when assessing patients with TR by echocardiography it is imperative to focus on four major aspects: evaluation of severity of TR, assessment of the etiology of TR, evaluation of the mechanism of TR and suitability for surgical or per-cutaneous repair. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00330620183022
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http://dx.doi.org/10.1016/j.pcad.2018.11.008DOI Listing
November 2018
5 Reads

Coexistent bicuspid aortic valve and mitral valve prolapse: epidemiology, phenotypic spectrum, and clinical implications.

Eur Heart J Cardiovasc Imaging 2018 Nov 15. Epub 2018 Nov 15.

Department of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, 55905 MN, USA.

Aims: Bicuspid aortic valve (BAV) and mitral valve prolapse (MVP) are common but the prevalence and significance of coexistent conditions are unknown. This study investigated the prevalence, phenotypic expression, and clinical significance of coexistent MVP-BAV.

Methods And Results: Retrospective comparison of MVP-BAV and MVP-tricuspid aortic valve (TAV) prevalence including de novo echocardiographic analysis of all MVP-BAV patients between 2005 and 2015 was performed. Read More

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https://academic.oup.com/ehjcimaging/advance-article/doi/10.
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http://dx.doi.org/10.1093/ehjci/jey166DOI Listing
November 2018
7 Reads

A rare complication of mitral valve replacement: Iatrogenic aortic valve perforation.

J Clin Ultrasound 2018 Nov 16. Epub 2018 Nov 16.

Cardiology Department, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Iatrogenic aortic valve injury after mitral valve surgery is a well-known but rare complication. Herein, we report a 62-year-old male patient who underwent mitral valve replacement surgery 12 years ago and developed moderate to severe aortic regurgitation immediately after surgery. Read More

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http://dx.doi.org/10.1002/jcu.22672DOI Listing
November 2018
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Influence of permanent pacemaker implantation after transcatheter aortic valve implantation with new-generation devices.

Neth Heart J 2018 Dec;26(12):620-627

Department of Internal Medicine II, University of Ulm, Ulm, Germany.

Objective: Permanent pacemaker implantation (PPMI) after transcatheter aortic valve implantation (TAVI) is the most common complication after the procedure. PPMI rates remain high with the new-generation TAVI devices despite improved outcomes concerning paravalvular aortic regurgitation and vascular access complications. However, the impact of PPMI on mortality and clinical outcome is still a matter of debate, and data with new-generation devices on this matter are scarce. Read More

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http://link.springer.com/10.1007/s12471-018-1194-1
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http://dx.doi.org/10.1007/s12471-018-1194-1DOI Listing
December 2018
4 Reads

Tachycardia after acute deceleration injury.

Heart 2018 Nov 15. Epub 2018 Nov 15.

Departments of Cardiology and Cardiac Surgery, University Hospital of Wales, Cardiff, UK.

A 29-year-old man crashed at high speed into another vehicle at traffic lights. He was able to get out of his van but then collapsed after running a few metres. On arrival in the emergency department he was conscious, with a pulse of 140 beats/min and blood pressure of 110/32 mm Hg. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314082DOI Listing
November 2018
1 Read

Severe Prosthetic Mitral Stenosis Misinterpreted as Severe Aortic Regurgitation.

J Cardiothorac Vasc Anesth 2018 Oct 19. Epub 2018 Oct 19.

Department of Cardiothoracic Anesthesiology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1053/j.jvca.2018.10.016DOI Listing
October 2018
2 Reads

The Duke minor criterion "predisposing heart condition" in native valve infective endocarditis - a systematic review.

Swiss Med Wkly 2018 11 15;148:w14675. Epub 2018 Nov 15.

, 3010, Bern, SWITZERLAND.

BACKGROUND The term “predisposition” is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis and as a criterion for diagnosing infective endocarditis according to the modified Duke criteria. The criterion for diagnosing infective endocarditis in native valves is not well defined. OBJECTIVES To identify conditions that increase the risk for infective endocarditis in native valves, for the diagnosis of infective endocarditis according to the modified Duke criteria. Read More

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https://doi.emh.ch/smw.2018.14675
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http://dx.doi.org/10.4414/smw.2018.14675DOI Listing
November 2018
5 Reads

Goal-directed therapy during transthoracic oesophageal resection does not improve outcome: Randomised controlled trial.

Eur J Anaesthesiol 2018 Nov 13. Epub 2018 Nov 13.

From the Department of Medical and Health Sciences and Department of Anaesthesiology and Intensive Care (HB, LN), and the Department of Clinical and Experimental Medicine and Department of Surgery, Linköping University, University Hospital, Linköping, Sweden (IH).

Background: Goal-directed therapy (GDT) is expected to be of highest benefit in high-risk surgery. Therefore, GDT is recommended during oesophageal resection, which carries a high risk of postoperative complications.

Objectives: The aim of this study was to confirm the hypothesis that GDT during oesophageal resection improves outcome compared with standard care. Read More

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http://dx.doi.org/10.1097/EJA.0000000000000908DOI Listing
November 2018
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Feasibility study of a synchronized diastolic injection with low contrast volume for proper quantitative assessment of aortic regurgitation in porcine models.

Catheter Cardiovasc Interv 2018 Nov 15. Epub 2018 Nov 15.

Imperial College London, London, United Kingdom.

Objectives: To evaluate the in vivo feasibility of aortography with one accurately timed diastolic low-volume contrast injection for quantitative assessment of aortic regurgitation (AR) post transcatheter aortic valve replacement (TAVR).

Background: With the rise of a minimalistic approach for TAVR, aortography (re)emerges as a pragmatic tool for AR assessment. In a mock circulation system, we have validated the accuracy of a single diastolic injection triggered by electrocardiogram (ECG) with low-contrast volume. Read More

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http://dx.doi.org/10.1002/ccd.27972DOI Listing
November 2018
1 Read
2.110 Impact Factor

Contemporaneous management of valvular heart disease and aortopathy in aircrew.

Heart 2019 Jan;105(Suppl 1):s57-s63

Royal Air Force Aviation Clinical Medicine Service, RAF Centre of Aviation Medicine, RAF Henlow, Bedfordshire, UK.

Valvular heart disease (VHD) is highly relevant in the aircrew population as it may limit appropriate augmentation of cardiac output in high-performance flying and predispose to arrhythmia. Aircrew with VHD require careful long-term follow-up to ensure that they can fly if it is safe and appropriate for them to do so. Anything greater than mild stenotic valve disease and/or moderate or greater regurgitation is usually associated with flight restrictions. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-313056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256303PMC
January 2019
7 Reads