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J Magn Reson Imaging 2022 Jun 21. Epub 2022 Jun 21.

Clinical Physiology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund.

Background: Neonates with critical congenital heart disease require early intervention. Four-dimensional (4D) flow may facilitate surgical planning and improve outcome, but accuracy and precision in neonates are unknown.

Purpose: To 1) validate two-dimensional (2D) and 4D flow MRI in a phantom and investigate the effect of spatial and temporal resolution; 2) investigate accuracy and precision of 4D flow and internal consistency of 2D and 4D flow in neonates; and 3) compare scan time of 4D flow to multiple 2D flows. Read More

J Cardiol 2022 Jun 17. Epub 2022 Jun 17.

Department of Neonatology, Toho-University Oomori Medical Center, Tokyo, Japan.

Background: The frequency, mortality, and morbidity of very low birth weight (VLBW) infants with congenital heart disease (CHD) in Asian countries are limited. In addition, little is known about the risk factors of death in these infants.

Methods: A retrospective, multicenter cohort study was conducted. Read More

JTCVS Tech 2022 Jun 22;13:18-21. Epub 2022 Feb 22.

Department of Cardiovascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong Province, China.

Heart 2022 Jun 16. Epub 2022 Jun 16.

Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Heart 2022 Jun 16. Epub 2022 Jun 16.

Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.

J Vasc Surg 2022 Jun 13. Epub 2022 Jun 13.

Faculty of Medicine, Department of Cardiovascular Surgery, University Heart Center Freiburg, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.

Objective: Formation of post-aortic coarctation aneurysms (pCoAA) is well described in the literature and carries a significant risk of rupture and death. Treatment strategies include open surgical, hybrid, and endovascular repair dependent on clinical presentation, risk assessment, and anatomy. The aim of this study is to report early and mid-term results of open surgical and endovascular repair of pCoAA. Read More

Front Cardiovasc Med 2022 25;9:817866. Epub 2022 May 25.

Cincinnati Children's Heart Institute and the Department of Pediatrics, University of Cincinnati, Cincinnati, OH, United States.

Current management of isolated CoA, localized narrowing of the aortic arch in the absence of other congenital heart disease, is a success story with improved prenatal diagnosis, high survival and improved understanding of long-term complication. Isolated CoA has heterogenous presentations, complex etiologic mechanisms, and progressive pathophysiologic changes that influence outcome. End-to-end or extended end-to-end anastomosis are the favored surgical approaches for isolated CoA in infants and transcatheter intervention is favored for children and adults. Read More

Sci Rep 2022 Jun 11;12(1):9718. Epub 2022 Jun 11.

Department of Mechanical Engineering, McMaster University, Hamilton, Canada, ON.

Accurate hemodynamic analysis is not only crucial for successful diagnosis of coarctation of the aorta (COA), but intervention decisions also rely on the hemodynamics assessment in both pre and post intervention states to minimize patient risks. Despite ongoing advances in surgical techniques for COA treatments, the impacts of extra-anatomic bypass grafting, a surgical technique to treat COA, on the aorta are not always benign. Our objective was to investigate the impact of bypass grafting on aortic hemodynamics. Read More

Ann Vasc Surg 2022 Jun 7. Epub 2022 Jun 7.

Department of Vascular Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address:

Background: Coarctation of the aorta with poststenotic aneurysms is rare and complex. Here we report a relatively large group of endovascular treatments for the disease.

Materials And Methods: Fifteen patients from two centers between 2006 and 2019 were included in the study. Read More

IDCases 2022 21;29:e01506. Epub 2022 May 21.

Laboratoire Bactériologie Hygiène, CHU Lille, Univ Lille, 59037 Lille, France.

is a member of the HACEK group of bacteria, responsible for infective endocarditis, mainly in patients with damaged or prosthetic valves. The low virulence of this organism can explain the insidious presentation and subacute or chronic progression of infective endocarditis. Here, a 41-year-old man with a past history of surgery for a Waldhausen type aortic coarctation was hospitalised with dyspnea and chest pains revealing an acute pulmonary oedema, without fever. Read More

Radiol Case Rep 2022 Aug 30;17(8):2689-2692. Epub 2022 May 30.

The American British Cowdray Medical Center, Radiology, Sur 136. 116 Col. Las Americas, Álvaro Obregón, 01120 Ciudad de México, México.

Aortic coarctation is a severe pathology that can be underdiagnosed in pediatric patients. We present 1 case of a patient diagnosed with aortic coarctation in the emergency department, referred by his treating physician when detecting high blood pressure figures. This study focuses on the diagnostic approach and Doppler ultrasound findings. Read More

Ultrasound Obstet Gynecol 2022 Jun 3. Epub 2022 Jun 3.

Bromtpon Centre for Fetal Cardiology, Royal Brompton and Harefield Hospitals, London.

Objectives: To describe the associated cardiac and extracardiac findings and estimate the prevalence of single left superior vena cava (LSVC) among fetuses referred for fetal echocardiography.

Methods: This is a retrospective case series study of fetuses diagnosed with situs solitus and single LSVC at the Brompton Centre for Fetal Cardiology, from October 2006 to December 2020. Prenatal and postnatal outcome data were collected. Read More

Front Cardiovasc Med 2022 17;9:870683. Epub 2022 May 17.

Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China.

Objective: The purpose of the study was to observe the elasticity of the ascending aorta (AAo) in normal fetuses and fetuses with coarctation of the aorta (CoA) by M-mode echocardiography.

Methods: This was a prospective clinical study performed on 16 fetuses with CoA and 48 gestational-age matched normal fetuses. The minimum internal diameter in the diastolic phase (Dmin) and the maximum internal diameter in the systolic phase (Dmax) of the AAo were measured by M-mode echocardiography. Read More

Eur Heart J 2022 Jun 2. Epub 2022 Jun 2.

Department of Cardiovascular Surgery, Shandong Provincial Hospital affiliated to Shandong First Medical University, No.324 Jingwu Road, Jinan, Shandong 250021, China.

Pediatr Cardiol 2022 May 30. Epub 2022 May 30.

Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, USA.

Surgical options for coarctation of aorta (CoA) with atrioventricular septal defect (AVSD) include single-stage repair vs. staged approach with neonatal CoA repair and delayed AVSD repair. The durability of left atrioventricular valve (LAVV) function after neonatal repair is questioned, and the optimal approach remains controversial. Read More

Curr Drug Discov Technol 2022 May 20. Epub 2022 May 20.

Fundación Cardiovascular de Colombia. Epidemiology department.

Background: Adequate oxygenation is essential in sick newborns. Each disease determines the target of oxygenation. Nevertheless, hyperoxia and hypoxia are related to adverse outcomes. Read More

Innovations (Phila) 2022 May-Jun;17(3):237-243. Epub 2022 May 26.

Center for Congenital Heart Disease/Pediatric Cardiology, Heart and Diabetes Center NRW, University Clinic of Ruhr University Bochum, Bad Oeynhausen, Germany.

Seven adult patients underwent a two-stage treatment of complex coarctation (CoA), including surgical revascularization of the left subclavian artery (LSA) to left common carotid artery (LCCA), followed by transcatheter covered stent implantation. The majority of patients (5 of 7, 71%) received 1 covered stent (covered Cheatham Platinum stent: 8 zig/45 mm [ = 2], 10 zig/60 mm [ = 1], 10 zig/65 mm [ = 1]; BeGraft: 24/48 mm [ = 2]). In 1 patient (14%), the implantation of 2 covered stents (BeGraft 20/48 mm) was necessary. Read More

JACC Case Rep 2022 May 18;4(10):587-591. Epub 2022 May 18.

Department of Cardiac, Thoracic, and Vascular Surgery, University Hospital of Martinique, Fort-de-France, Martinique (FWI), France.

We describe the case of a patient who developed resistant hypertension due to a giant atheroma with acquired physiologic mimic of coarctation of the aorta. This presentation illustrates an extremely rare etiology to consider in adults in whom aortic isthmus stenosis remains often of congenital origin. (). Read More

World J Clin Cases 2022 Apr;10(11):3472-3477

Department of Radiology, Sichuan Cancer Hospital, Chengdu 610000, Sichuan Province, China.

Background: Aortic coarctation (CoA) is usually confused with interrupted aortic arch (IAA), especially adult type A interrupted aortic arch, due to their similar anatomical location. Although the main difference between them is whether arterial lumen exhibits continuity or not, the clinical manifestations are similar and connection exists between them. Adult type A IAA is considered as an extreme form of CoA, which is complete discontinuity of aortic function and lumen caused by degenerative arterial coarctation. Read More

CASE (Phila) 2022 May 17;6(3):114-118. Epub 2022 Feb 17.

Division of Pediatric Cardiology, Department of Pediatrics, Rady Children's Hospital, UC San Diego School of Medicine, San Diego, California.

Front Surg 2022 28;9:902108. Epub 2022 Apr 28.

Division of Nephrology, Department of Medicine, West China Hospital of Sichuan University, Chengdu, China.

Background: Acute type A aortic coarctation (AAAD) is a highly deadly and serious life-threatening disease. The purpose of this study was to estimate the predictive value of peak procalcitonin, interleukin-6, and C-reactive protein levels on adverse renal outcomes and mortality in patients undergoing surgery for AAAD.

Methods: Perioperative peak PCT, CRP, and IL-6 levels were retrospectively collected in 331 patients hospitalized with AAAD from 2009 to 2021. Read More

An Pediatr (Engl Ed) 2022 06 12;96(6):542-544. Epub 2022 May 12.

Cardiología Pediátrica, Hospital Universitario de Cruces, Baracaldo, Vizcaya, Spain.

J Pediatr 2022 05;244:91

Department of Pediatric Research, University of Oslo, Oslo, Norway; Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Ann Pediatr Cardiol 2021 Oct-Dec;14(4):561-563. Epub 2022 Mar 25.

Department of Radiology, Thomas Jefferson University Hospitals, Philadelphia, PA 19107, USA.

Midaortic syndrome (MAS) is characterized by narrowing of the descending aorta between the distal aortic arch and the aortic bifurcation. We present the case of a 4-year-old male presenting with a murmur and diagnosed with MAS. He was treated with a thoracoabdominal bypass graft. Read More

Comput Methods Programs Biomed 2022 Jun 21;221:106826. Epub 2022 Apr 21.

State Key Laboratory of Clean Energy Utilization, Zhejiang University, 38 Zheda Road, Hangzhou 310027, China; Shanghai Institute for Advanced Study of Zhejiang University, Shanghai, China.

Background And Objectives: The aorta serves as the main tube of the human blood circulation system. Energy loss (EL) occurs when blood flows through the aorta and there may be a potential correlation between EL and aortic diseases. However, the components of blood flow EL are still not fully understood. Read More

Diagn Interv Imaging 2022 May 3. Epub 2022 May 3.

Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago 60611, IL, USA; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston 60208, IL, USA.

Purpose: The purpose of this study was to investigate the relationships between hemodynamic parameters and longitudinal changes in aortic dimensions on four-dimensional (4D) flow magnetic resonance imaging (MRI) in patients with bicuspid aortic valve (BAV) and repaired coarctation.

Materials And Methods: The study retrospectively included patients with BAV and childhood coarctation repair who had at least two cardiothoracic MRI examinations including 4D flow MRI at baseline and follow-up. Analysis included the calculation of aortic peak velocities, wall shear stress (WSS), pulse wave velocity (PWV), aortic dimensions and annual growth rates. Read More

Pediatr Int 2022 01;64(1):e15201

Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.

Pediatr Cardiol 2022 May 6. Epub 2022 May 6.

Department of Pediatrics, Division of Pediatric Cardiology, Children's Hospital of New Jersey, Newark Beth Israel, Newark, NJ, USA.

Coarctation of the aorta is a form of congenital heart disease requiring surgical intervention. If is often associated with other forms of congenital heart disease. Anomalous origin of the left coronary artery (ALCA) from the opposite sinus of Valsalva is implicated in sudden cardiac death. Read More

J Ginseng Res 2022 Mar 5;46(2):235-247. Epub 2021 Jun 5.

National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular mechanisms involved.

Methods: The effects of ginsenoside Rg3 on heart and mitochondrial function were investigated by treating TAC-induced heart failure in mice. Read More

Health Sci Rep 2022 May 25;5(3):e625. Epub 2022 Apr 25.

Cliniques Universitaires Saint-Luc UCL Brussels Belgium.

Background And Aims: Abdominal coarctations are rare. Surgical treatment is difficult and requires re-interventions to adjust the graft material to patient growth. We report effective treatment by interventional catheterization in an infant with the concern to allow adjustment for growth and prevention of vessel damage. Read More