Search Our Scientific Publications & Authors

Psychiatry Res 2019 Mar 26;276:45-55. Epub 2019 Mar 26.

Autism Clinic for Translational Research, Brain and Mind Centre, Central Clinical School, Faculty of Medicine, University of Sydney, Camperdown, Sydney, NSW 2050 Australia. Electronic address:

Social functioning is an important component of mental disorders for assessment and treatment. There is no recognised self-report instrument to measure social functioning across disorders where social impairment is significant. The Social Functioning Scale (SFS) has, however, been used to assess social functioning in psychotic disorders, including Schizophrenia and Early Psychosis. Read More

J Pain Symptom Manage 2019 Apr 17. Epub 2019 Apr 17.

Weill Cornell Medicine, Division of Geriatric and Palliative Medicine, New York, NY, USA.

Context: Rates of psychological symptoms for patients with serious illness are high, but there has been limited research investigating psychological symptoms at the very end of life.

Objectives: To better understand the prevalence, severity and correlates of psychological distress at the very end of life.

Methods: This retrospective cross-sectional study utilized caregiver proxy interviews. Read More

J Pain Symptom Manage 2019 Apr 17. Epub 2019 Apr 17.

Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, Taiwan; Department of Nursing, Chang Gung Memorial Hospital at Kaohsiung, Taiwan. Electronic address:

Purpose: To examine the effectiveness of an advance care planning (ACP) intervention in facilitating concordance between cancer patients' preferred and received life-sustaining treatment (LST) states and to explore modifiable factors facilitating or impeding such concordance.

Methods: Terminal cancer patients (N=460) were randomly assigned 1:1 to the experimental and control arms of a randomized clinical trial, with 430 deceased participants comprising the final sample. States of preferred LSTs (cardiopulmonary resuscitation, intensive care unit care, chest compression, intubation with mechanical ventilation, intravenous nutrition, and nasogastric tube feeding) and LSTs received in the last month were examined by hidden Markov modeling. Read More

J Am Acad Child Adolesc Psychiatry 2019 Apr 17. Epub 2019 Apr 17.

University of Vermont, Burlington; Vermont Center on Behavior and Health, University of Vermont, Burlington.

Objective: To characterize the structural and functional neurobiology of a large group of adolescents exhibiting a behaviorally and emotionally dysregulated phenotype.

Method: Age 14 adolescents from the IMAGEN study were investigated. Latent class analysis (LCA) on the Strengths and Difficulties Questionnaire (SDQ) was used to identify a class of individuals with elevated behavioral and emotional difficulties ("dysregulated"; n=233) who were compared to a matched sample from a low symptom class (controls, n=233). Read More

J Am Acad Child Adolesc Psychiatry 2019 Apr 17. Epub 2019 Apr 17.

Objective: Youth depression is a debilitating condition that constitutes a major public health concern. A 2006 meta-analysis found modest benefits for psychotherapy vs. control. Read More

Neurosci Lett 2019 Apr 17. Epub 2019 Apr 17.

Department of Psychopharmacology, Qiqihar Medical University, Qiqihar, 161006, China; MRC-GHF, College of Korean Medicine, Daegu Haany University, Gyeongsan, 38610, Republic of Korea. Electronic address:

Noradrenergic projections from the nucleus tractus solitarius (NTS) to the hypothalamic paraventricular nucleus (PVN) are involved in nicotine (Nic) dependence. Nic induces hypothalamic norepinephrine (NE) release through N-methyl-D-aspartate receptors (NMDARs) and nitric oxide in the NTS. However, acupuncture attenuates Nic withdrawal-induced anxiety. Read More

Behav Brain Res 2019 Apr 17:111917. Epub 2019 Apr 17.

Psychiatric Neuroscience Lab, Discipline of Psychiatry, University of Adelaide, Adelaide, SA, Australia; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, VIC, Australia. Electronic address:

Background: Environmental enrichment (EE) has been shown to modulate behavior and hippocampal gene expression; however, the currently available literature does not explain the differential effects that may relate to the duration of EE.

Aim: To investigate the differential effects of short- and long-term EE on locomotion, anxiety-, depressive- and cognition-like behaviors, and hippocampal gene expression under physiological conditions.

Methods: We assigned either short-term or long-term intervention with respective controls to healthy C57BL/6 mice (n = 12-16/group). Read More

Neurosci Biobehav Rev 2019 Apr 17. Epub 2019 Apr 17.

Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, East Providence, RI, United States.

With growing interest in the gut microbiome, prebiotics and probiotics have received considerable attention as potential treatments for depression and anxiety. We conducted a random-effects meta-analysis of 34 controlled clinical trials evaluating the effects of prebiotics and probiotics on depression and anxiety. Prebiotics did not differ from placebo for depression (d=-. Read More

J Clin Psychol 2019 Apr 20. Epub 2019 Apr 20.

Department of Clinical Psychology and Psychotherapy/International Institute for the Advanced Study of Psychotherapy and Applied Mental Health, Babeş-Bolyai University, No 37 Republicii Street, Cluj-Napoca, Romania.

Objective: Cognitive-behavior therapy (CBT) is considered the "golden standard" psychotherapy for generalized anxiety disorder (GAD) but, at this point, we have little information about differences among various CBT approaches.

Method: We conducted a randomized controlled trial to compare three CBT protocols for GAD: (a) Cognitive Therapy/Borkovec's treatment package; (b) Rational Emotive Behavior Therapy, and (c) Acceptance and Commitment Therapy/Acceptance-based behavioral therapy. A number of 75 patients diagnosed with GAD, aged between 20 and 51 (m = 27. Read More

Br J Dev Psychol 2019 Apr 19. Epub 2019 Apr 19.

Department of Social Psychology, University of Amsterdam, The Netherlands.

Previous research has shown that children's intergroup similarity judgements are based not only on ethnicity but also on other dimensions such as sports interest. The present research investigates the role of personality in perceived similarity between ingroup children and refugee outgroup children. A study was conducted among 9- to 12-year-old children (N = 124) at two elementary schools in the Netherlands. Read More

Perspect Psychiatr Care 2019 Apr 20. Epub 2019 Apr 20.

Department of Nursing, Faculty of Health Sciences, Atilim University, Golbasi, Ankara, Turkey.

Purpose: The purpose of this study is to determine the levels of anxiety, depression, social support, and nursing care needed by women undergoing therapeutic abortion.

Designs And Methods: Sixty women were administered a sociodemographic form, the Hospital Anxiety Depression Scale and the Multidimensional Perceived Social Support Scale.

Results: More than half of the women experienced anxiety (61. Read More

J Behav Med 2019 Apr 19. Epub 2019 Apr 19.

Department of Sociology and Social Work, Shanghai Normal University, Shanghai, China.

Cognitive-behavioral therapy (CBT) is well supported for treating depressive and anxiety disorders. Trials of CBT for anxiety and depression in primary care have increased over the past decade, yet only one meta-analysis, published in 2015, examined this topic and the scope of that review is relatively narrow. This study conducted a systematic review and meta-analysis of primary care based CBT for depression and anxiety. Read More

Eur Child Adolesc Psychiatry 2019 Apr 19. Epub 2019 Apr 19.

Norwegian Centre for Violence and Traumatic Stress Studies, Gullhaugveien 1-3, Nydalen, Oslo, Norway.

Unaccompanied refugee minors are a particularly vulnerable group. The aim of this study is to increase our knowledge about possible pathways to well-being and integration for unaccompanied refugee minors as they strive to establish new lives in a host county. The present study followed a group of youth who fled to Norway without their caregivers at three time points; 6 months (n = 95; M age = 13. Read More

J Youth Adolesc 2019 Apr 19. Epub 2019 Apr 19.

Health Promotion Research Centre, National University of Ireland Galway, Galway, Ireland.

School-based social and emotional learning programs aim to provide students with the skills they need to deal with life challenges, thereby enhancing their social and emotional wellbeing, academic outcomes, and reducing their risk of mental health difficulties. While there is a robust evidence base on the effectiveness of these programs originating from the US, there is a relative paucity of research on how these programs impact young people in other county contexts, especially for older adolescents and those at higher risk. This study sets out to address this research gap by evaluating the effectiveness of a social emotional learning program designed for older adolescents in Ireland, the MindOut program. Read More

J Autism Dev Disord 2019 Apr 19. Epub 2019 Apr 19.

Massachusetts General Hospital, Boston, MA, USA.

Imaging technologies such as positron emission tomography (PET) and magnetic resonance imaging (MRI) present unparalleled opportunities to investigate the neural basis of autism spectrum disorder (ASD). However, challenges such as deficits in social interaction, anxiety around new experiences, impaired language abilities, and hypersensitivity to sensory stimuli make participating in neuroimaging studies challenging for individuals with ASD. In this commentary, we describe the existent training protocols for preparing individuals with ASD for PET/MRI scans and our own experience developing a training protocol to facilitate the inclusion of low-functioning adults with ASD in PET-MRI studies. Read More

Mil Med 2019 Apr 20. Epub 2019 Apr 20.

Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, Tampa, FL 33612.

Introduction: The United States has been actively involved in major armed conflicts over the last 15 years. As a result, a significant proportion of active duty service personnel and returning veterans have endured combat, putting them at risk for developing post-traumatic stress disorder (PTSD), a disabling disorder that may occur after exposure to a traumatic event. Current therapies often require long-term, time-intensive and costly commitment from the patient and have variable degrees of success. Read More

Inj Prev 2019 Apr 19. Epub 2019 Apr 19.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Introduction: Understanding the impact of comorbidity on health outcomes is important given that comorbidities can affect survival, morbidity, service delivery costs and healthcare utilisation. However, little is known about the types of comorbidities affecting specific health outcomes after minor to moderate road trauma.

Methods: This study involved 1574 participants who claimed injury compensation following transport-related injury. Read More

J Anxiety Disord 2019 Apr 16. Epub 2019 Apr 16.

Department of Psychology, Stockholm University, Stockholm, Sweden; Department of Psychology, University of Southern Denmark, Odense, Denmark.

J Psychosom Res 2019 Apr 12. Epub 2019 Apr 12.

Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA; William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN, USA. Electronic address:

Objective: Cannabis is the most commonly used non-alcohol intoxicant in the general population. There are no consistent guidelines on the implications of cannabis abuse and dependence (CAD) in kidney transplant candidates. The aims of this study were to characterize kidney transplant candidates with comorbid CAD and examine the implications of CAD on transplant candidacy. Read More

Biochem Biophys Res Commun 2019 Apr 17. Epub 2019 Apr 17.

Department of Endocrinology, Diabetes and Geriatric Medicine, Akita University Graduate School of Medicine, Japan. Electronic address:

Aims/introduction: Caloric restriction (CR) promotes longevity and exerts anti-aging effects by increasing Sirtuin production and activation. Gastric inhibitory polypeptide (GIP), a gastrointestinal peptide hormone, exerts various effects on pancreatic β-cells and extra-pancreatic tissues. GIP promotes glucose-dependent augmentation of insulin secretion and uptake of nutrients into the adipose tissue. Read More

Compr Psychiatry 2019 Apr 3. Epub 2019 Apr 3.

Hacettepe University Faculty of Medicine, Department of Child and Adolescent Psychiatry, Ankara, Turkey. Electronic address:

Aim: The aim of this study is to investigate parental attitudes, perceived social support, emotion regulation and the accompanying psychiatric disorders seen in adolescents who, having been diagnosed with Internet Addiction (IA), were referred to an outpatient child and adolescent psychiatric clinic.

Methods: Of 176 adolescents aged 12-17, 40 were included in the study group. These scored 80 or higher on Young's Internet Addiction Test (IAT) and met Young's diagnostic criteria for IA based on psychiatric interviews. Read More

Complement Ther Clin Pract 2019 May 27;35:353-360. Epub 2019 Mar 27.

(k)Israel Center for Disease Control, Ministry of Health, Israel; School of Public Health, University of Haifa, Israel. Electronic address:

Complement Ther Clin Pract 2019 May 15;35:290-295. Epub 2019 Mar 15.

Student Research Committee, Nursing and Midwifery School, Iran University of Medical Sciences, Tehran, Iran.

Introduction: and purpose: Aromatherapy is a known popular method to reduce the symptoms of various physiologic processes and diseases. The aim of the study was to determine whether aromatherapy improves symptoms commonly experienced by women during the postpartum period.

Methods: In the present systematic review, four international databases (PubMed, Google Scholar, Web of Science, and Scopus) were searched from inception of databases through August 2018. Read More

Complement Ther Clin Pract 2019 May 12;35:259-264. Epub 2019 Mar 12.

Kutahya Health Sciences University, Faculty of Health Sciences, Department of Obstetrics and Gynecology Nursing, Kutahya, Turkey. Electronic address:

Objective: This study aimed to determine the effect of music that was listened to by pregnant women during the non-stress test (NST) on the test result and maternal anxiety.

Materials And Methods: The study utilized a non-randomized controlled trial design. Sequential sample selection method was used. Read More

Complement Ther Clin Pract 2019 May 27;35:237-252. Epub 2019 Feb 27.

Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of Korea; Department of Korean Medicine, Kyung Hee University Korean Medicine Hospital at Gangdong, 892, Dongnam-ro, Gangdong-gu, Seoul, Republic of Korea. Electronic address:

The study was conducted to investigate the efficacy and safety of herbal medicine (HM) for post-stroke anxiety (PSA). Through comprehensive searches, twenty randomized controlled trials were included. Meta-analysis showed that compared to the HM group, the conventional pharmacotherapy group showed significantly lower Hamilton anxiety rating scale (HAMA) score after 1 week of treatment, but not after 2, 4, and 6 weeks of treatment, and higher HAMA score after 8 weeks and 3 months of treatment. Read More

Complement Ther Clin Pract 2019 May 16;35:18-21. Epub 2019 Jan 16.

Department of Rheumatology, Ajou University School of Medicine, Suwon, South Korea. Electronic address:

Background: and purpose: The stress and systemic lupus erythematosus (SLE) are intertwined and affecting each other. This pilot study evaluated the mindfulness-based cognitive therapy (MBCT) in Korean patients with SLE.

Materials And Methods: The Korean version of the Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), Satisfaction with Life Scale (SWLS), and Perceived Stress Scale (PSS) were evaluated for the effect of the MBCT in 25 patients. Read More

Complement Ther Clin Pract 2019 May 7;35:109-120. Epub 2019 Feb 7.

Faculty of Health Science, Nursing Department, Afyonkarahisar University of Health Science, 03200, Afyonkarahisar, Turkey. Electronic address:

Objective: The present investigation analyses the studies of music intervention carried out by nurse researchers, or a research group including nurses, making use of a systematic mapping method to determine the trends in this field.

Method: In this study, based on a systematic mapping method, 68 out of the 809 studies published between 2013 and 2017, were evaluated.

Results: In 87. Read More

J Clin Med 2019 Apr 18;8(4). Epub 2019 Apr 18.

Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, 11528 Athens, Greece.

Patients with serious psychiatric diseases (major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia and psychotic disorder) often complain about sleepiness during the day, fatigue, low energy, concentration problems, and insomnia; unfortunately, many of these symptoms are also frequent in patients with Obstructive Sleep Apnea (OSA). However, existing data about the clinical appearance of OSA in Psychiatric Disease are generally missing. The aim of our study was a detailed and focused evaluation of OSA in Psychiatric Disease, in terms of symptoms, comorbidities, clinical characteristics, daytime respiratory function, and overnight polysomnography data. Read More

Int J Environ Res Public Health 2019 Apr 18;16(8). Epub 2019 Apr 18.

Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.

Criminal police officers are viewed as having a very tiring and stressful job, one that is closely correlated with work disability and other factors that might impair quality of life. Few studies have addressed the issue of health-related quality of life (HRQoL) in this population. Thus, this study aimed to assess the HRQoL of criminal police officers compared with the general adult population and identify determinants associated with HRQoL. Read More

Environ Pollut 2019 Apr 9;250:312-322. Epub 2019 Apr 9.

Laboratory of Endocrine Physiology, Roberto Alcantara Gomes Biology Institute, State University of Rio de Janeiro, RJ, Brazil. Electronic address:

Bisphenol S (BPS) has replaced bisphenol A (BPA), a known non-persistent endocrine disrupting chemical, in several products. Considering that little is known regarding BPS effects, especially during critical windows of ontogenetic development, and that BPA, which is quite similar to BPS, is know to be transferred to the offspring via the placenta and milk, in the present study we investigated the behavioral, biochemical and endocrine profiles of Wistar rats born from dams that were BPS-exposed [groups: BPS10 (10 μg/kg/day), BPS50 (50 μg/kg/day)] during pregnancy and lactation. Due to the non-monotonic dose-response effect of bisphenol, the data of both BPS groups were directly compared with those of the controls, not to each other. Read More

Psychoneuroendocrinology 2019 Mar 22;106:206-215. Epub 2019 Mar 22.

Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, 113-8657, Japan; ERATO Touhara Chemosensory Signal Project, JST, The University of Tokyo, Tokyo, 113-8657, Japan; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo Institutes for Advanced Study, Tokyo, 113-0033 Japan. Electronic address:

Unpleasant odors impair our mood and may affect physical health, even when the odorants are not toxic. A possible cause for such negative effects is stress induced by odors; however, whether the unpleasantness itself elicited stress or not has not been clear. Thus, we examined whether unpleasantness of odors induced the stress responses of emotion, the hypothalamic-pituitary-adrenal (HPA) axis, and the sympathetic nervous system (SNS). Read More

J Affect Disord 2019 Mar 30;252:435-439. Epub 2019 Mar 30.

The Adelaide Clinic, Ramsay Health Care (SA) Mental Health Services, South Australia, Australia; Discipline of Psychiatry, School of Medicine, The University of Adelaide, South Australia, Australia; Northern Adelaide Local Health Network, South Australia, Australia. Electronic address:

Background: The presence of comorbid anxiety is generally associated with poorer treatment outcomes in people with depression. Repetitive transcranial magnetic stimulation (rTMS) has been shown to be effective for treatment resistant depression, but there has been little research examining rTMS in depressed patients with comorbid anxiety disorders. This study aimed to investigate the efficacy of rTMS in patients with treatment resistant Major Depressive Disorder (MDD) and comorbid anxiety disorders. Read More

J Behav Ther Exp Psychiatry 2019 Apr 3;64:123-132. Epub 2019 Apr 3.

ADAPT lab, Department of Psychology, University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WT, Amsterdam, the Netherlands; Department of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WT, Amsterdam, the Netherlands. Electronic address:

Background And Objectives: Although induced changes in interpretation bias can lead to reduced levels of stress reactivity, results are often inconsistent. One possible cause of the inconsistencies in the effects of interpretation bias modification (IBM) on stress reactivity is the degree to which participants engaged in emotion regulation while being exposed to stressors. In this study, we distinguished between the effects of IBM on natural, unregulated stress reactivity and the effects of IBM on people's ability to up- or downregulate this stress reactivity. Read More

J Eur Acad Dermatol Venereol 2019 Apr 19. Epub 2019 Apr 19.

European Federation of Allergy and Airway Diseases Patient's Associations, Brussels, Belgium.

Background: Atopic eczema (AE, atopic dermatitis) is one the most common non-communicable inflammatory skin diseases affecting 1-5% of the adult population in Europe with marked impairment in quality of life. In spite of great progress in understanding the pathophysiology of disturbed skin barrier and immune deviation, AE still represents a problem in daily clinical practice. Furthermore, the true impact of AE on individual suffering is often not recognized. Read More

Int J Qual Stud Health Well-being 2019 Dec;14(1):1595957

a Faculty of Nursing, Department of Public Health and Pediatrics Sciences , University of Turin , Turin , Italy.

After an acute cardiac event, many patients experience emotional disturbance. This is a normal response to the event and to hospitalization, but, if not treated with emotive and social support, the symptoms can evolve, resulting in emotional and behavioural disorders. The aim of the study was to evaluate the outcome of the use of a new nursing relational tool, designed to support patients' emotional recovery. Read More

Multivariate Behav Res 2019 Apr 19:1-19. Epub 2019 Apr 19.

d Department of Psychiatry , Leiden University Medical Centre , Leiden , the Netherlands.

Careless responding by mental health patients on self-report assessments is rarely investigated in routine care despite the potential for serious consequences such as faulty clinical decisions. We investigated validity indices most appropriate for detecting careless responding in routine outcome monitoring (ROM) in mental health-care. First, we reviewed indices proposed in previous research for their suitability in ROM. Read More

Anxiety Stress Coping 2019 Apr 19:1-16. Epub 2019 Apr 19.

a Institute of Psychology , University of Lausanne , Lausanne , Switzerland.

Background And Objectives: Emotion regulation involves attempts to influence emotion unfolding and may target experiential, expressive and physiological responses. Several strategies can be used, such as reappraisal (re-evaluating the emotional situation to reduce its emotional meaning) or distraction (turning the attention toward non-emotional aspects of the situation). Previous research on these regulation strategies produced contrasting results regarding their efficiency and we hypothesize that this could be due to individual differences such as trait anxiety. Read More

Cell Physiol Biochem 2019 ;52(5):1203-1222

Department of Zoology, Bharathiar University, Coimbatore, India.

Background/aims: Agriculture and industrial expansion in recent years have resulted in the undue discharge of arsenic into the environment, building arsenic toxicity a major worldwide anxiety. Oxidative stress is considered as the most conspicuous effect of arsenic toxicity. The current study was designed to evaluate the protective ability of sulforaphane (SFN) against arsenic (As) induced hepatotoxicity by activation of PI3K induced Akt and Nrf2 mediated signaling pathway. Read More

Perspect Psychiatr Care 2019 Apr 18. Epub 2019 Apr 18.

Department of Nursing, Trakya University Keşan Hakkı Yörük School of Health, Edirne, Turkey.

Purpose: This study aims to conduct reliability and validity study of the Turkish version of the Postpartum Specific Anxiety Scale (PSAS), which determines the anxiety of women in the postpartum period.

Design And Methods: This methodological study included 275 women.

Results: The scale had a single factor structure, which had the factor load in the appropriate range (0. Read More

Br J Soc Psychol 2019 Apr 19. Epub 2019 Apr 19.

University of Sarajevo, Bosnia-Herzegovina.

Studies have shown that affective states could be used as diagnostic information for the assessment of situational demands and that, as such, they can regulate resource mobilization. Accordingly, it was found that negative feelings cause overestimation of situational demands, which then leads to effort mobilization during performance on easy tasks but disengagement on difficult tasks. The present research investigated whether this emotion-motivation link could explain the usual differences in achievement on easy and difficult tasks under stereotype threat (ST). Read More

Curr Nutr Rep 2019 Apr 18. Epub 2019 Apr 18.

Program in Pharmacology and Experimental Therapeutics and Pharmacology and Drug Development, Sackler School of Graduate Biomedical Sciences and Department of Immunology, Tufts University School of Medicine, Boston, MA, 02111, USA.

Purpose Of Review: Dietary obesity is primarily attributed to an imbalance between food intake and energy expenditure. Adherence to lifestyle interventions reducing weight is typically low. As a result, obesity becomes a chronic state with increased co-morbidities such as insulin resistance and diabetes. Read More

J Behav Health Serv Res 2019 Apr 17. Epub 2019 Apr 17.

University of Pennsylvania, 3535 Market St. 3rd Floor, Philadelphia, PA, 19104, USA.

Youth psychosocial treatments have proliferated over many decades and the time is ripe to examine the unique contribution of these treatments. Six hundred eighty-nine randomized clinical trials were examined from the PracticeWise Evidence-Based Services Database, an ongoing data source of youth psychosocial literature. A number of studies, treatment protocols, and practice elements across 11 youth problem areas (e. Read More

J Behav Health Serv Res 2019 Apr 17. Epub 2019 Apr 17.

Department of Health Sciences, University West, 46186, Trollhättan, Sweden.

The study aimed to evaluate an integrated intensive cognitive behavioral therapy (CBT) group treatment for people with substance-related syndrome in outpatient care and to identify eventual gender differences. The study population consisted of 35 outpatients (18 male, 17 female) at a clinic in Western Sweden. The patients completed a four-month period of intensive group therapy and participated in the data collection at admission and discharge. Read More

Psychiatr Q 2019 Apr 18. Epub 2019 Apr 18.

Physical Education Institute, Hunan First Normal University, NO.1015, The Third Fenglin Road, Changsha, 410205, China.

Exercise dependence is a psychological problem that cannot be ignored and is positively related to anxiety and depression of college students. However, only a few effective intervention methods are available to deal with exercise dependence. This study aims to investigate the intervention effects of motivation interviewing Chinese modified on the mental health of college students with exercise dependence. Read More

Support Care Cancer 2019 Apr 18. Epub 2019 Apr 18.

Department of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Philipp-Rosenthal-Strasse 55, 04103, Leipzig, Germany.

Purpose: Our study provides data on depression and anxiety in long-term cancer survivors, in men, women and various age groups, as well as identifies associated factors and coping-related resources.

Methods: We present data obtained from 1002 cancer survivors across a large variety of tumour entities 5 years (cohort 1) and 10 years (cohort 2) after diagnosis, in a cross-sectional study. We analysed depression (PHQ-9) and anxiety (GAD-7) symptomatology in comparison with two large age- and sex-matched samples randomly selected from the general population. Read More

Oxid Med Cell Longev 2019 14;2019:5452727. Epub 2019 Mar 14.

Laboratory of Pharmacology of Inflammation and Behavior, Pharmacy Faculty, Institute of Health Sciences, Federal University of Pará, Belém, Pará, Brazil.

Ketamine is used in clinical practice as an anesthetic that pharmacologically modulates neurotransmission in postsynaptic receptors, such as NMDA receptors. However, widespread recreational use of ketamine in "party drug" worldwide since the 1990s quickly spread to the Asian orient region. Thus, this study aimed at investigating the behavioral and oxidative effects after immediate withdrawal of intermittent administration of ketamine in adolescent female rats. Read More

Front Psychol 2019 2;10:748. Epub 2019 Apr 2.

Animal Behavior Laboratory, Fundación Universitaria Konrad Lorenz, Bogotá, Colombia.

Despite the wide implementation of the elevated plus-maze (EPM) test to assess anxiety-related behaviors in rodents, the interpretation of these measures in gerbils has received limited attention. Here, male gerbils were treated with vehicle or diazepam, followed by a 20-min EPM session. EPM data were subjected to minute-by-minute, 5-min bins and factor analyses. Read More

Front Pharmacol 2019 2;10:318. Epub 2019 Apr 2.

Institute of Clinical Pharmacy and Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, China.

Brain insulin signaling is accounted for the development of a variety of neuropsychiatric disorders, such as anxiety and depression, whereas both inflammation and the activated renin-angiotensin system (RAS) are two major contributors to insulin resistance. Intriguingly, inflammation and RAS can activate each other, forming a positive feedback loop that would result in exacerbated unwanted tissue damage. To further examine the interrelationship among insulin signaling, neuroinflammation and RAS in the brain, the effect of repeated lipopolysaccharide (LPS) exposure and co-treatment with the angiotensin II (Ang II) receptor type 1 (AT1) blocker, candesartan (Cand), on anxiety and depression-like behaviors, RAS, neuroinflammation and insulin signaling was explored. Read More