214,917 results match your criteria Anxiety


Relationship between anxiety, depression, sex, obesity, and internet addiction in Chinese adolescents: A short-term longitudinal study.

Addict Behav 2018 Dec 7;90:421-427. Epub 2018 Dec 7.

Research Institute on Addictions, University at Buffalo, State University of New York, Buffalo, NY, United States. Electronic address:

Associations between anxiety, depression and adolescent Internet addiction have been well documented in the literature; however, few published studies have examined these relationships considering the developmental trajectory courses of adolescent Internet addiction as well as the individual differences over time. Using a sample of 1545 Chinese adolescents and 3 waves of data over six months, we examined the longitudinal associations between anxiety and depression and Internet addiction, considering sex and obesity. We used latent growth curve modeling (LGCM) to examine the overall conditions of Internet addiction, and latent class growth modeling (LCGM) to determine adolescent developmental membership for Internet addiction. Read More

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December 2018

The association between the longitudinal course of common mental disorders and subsequent physical activity status in young adults: A 30-year birth cohort study.

J Psychiatr Res 2018 Dec 6;109:173-177. Epub 2018 Dec 6.

Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia; School of Public Health, The University of Queensland, Herston, Australia; Metro North Mental Health, Royal Brisbane and Women's Hospital, Herston, Australia.

Low physical activity is a major public health concern. There has been extensive research examining the role of physical activity as a potentially modifiable risk factor for the onset of mental illness. However, fewer studies have reported how mental disorders affect future physical activity. Read More

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December 2018
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How does self-esteem affect mobile phone addiction? The mediating role of social anxiety and interpersonal sensitivity.

Psychiatry Res 2018 Dec 6;271:526-531. Epub 2018 Dec 6.

College of Humanities, Hubei University of Chinese Medicine, China.

Low self-esteem is an important factor influencing mobile phone addiction, which has been well documented. However, little research focused on the mechanism underlying the association between self-esteem and mobile phone addiction. We hypothesized that social anxiety and interpersonal sensitivity may mediate the relationship between self-esteem and mobile phone addiction. Read More

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December 2018

Religious fundamentalism is associated with hyperactive performance monitoring: ERP evidence from correct and erroneous responses.

Biol Psychol 2018 Dec 12. Epub 2018 Dec 12.

Institute of Psychology, Jagiellonian University, Ingardena 6, 30-060 Kraków, Poland.

The aim of the current study was to examine whether action monitoring is associated with religious fundamentalism. Participants performed a stop-signal task that required response inhibition to a simple auditory tone. The level of their religious fundamentalism was measured on a scale. Read More

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December 2018

Morus alba L. Diminishes visceral adiposity, insulin resistance, behavioral alterations via regulation of gene expression of leptin, resistin and adiponectin in rats fed a high-cholesterol diet.

Physiol Behav 2018 Dec 12. Epub 2018 Dec 12.

Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt. Electronic address:

Ethanolic extract of leaves of Morus alba L. (M. alba), known as white mulberry, was orally administered (100 mg/kg b. Read More

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December 2018

Maternal and offspring MTHFR genotypes interact in a mouse model to induce ASD-like behavior.

Genes Brain Behav 2018 Dec 15:e12547. Epub 2018 Dec 15.

Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Individuals with autism constitute a variable population whose members are spread along the autism spectrum. Sub-populations within that spectrum exhibit other conditions, such as anxiety, intellectual disabilities, hyperactivity and epilepsy, with different severities and co-occurrences. Among the genes associated with the increased risk for autism is the methylenetetrahydrofolate-reductase (MTHFR) 677C>T polymorphism, which impairs one-carbon metabolic pathway efficiency. Read More

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December 2018

Anxiety and exploratory behavior in the African striped mouse, Rhabdomys, taxa are partially modified by the physical rearing environment.

Dev Psychobiol 2018 Dec 14. Epub 2018 Dec 14.

School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, South Africa.

The environment may modulate genetic influences on behavioral expression. We investigated whether the physical rearing environment modulates anxiety and exploratory behavior in four populations, representing three species, of the striped mouse Rhabdomys. One population originated from an arid, open habitat and the others from grassy, covered habitats, and two species occurred in sympatry. Read More

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December 2018

Efficacy of Endo-Ice followed by intrapulpal ice application as an adjunct to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis-a randomized controlled trial.

Clin Oral Investig 2018 Dec 14. Epub 2018 Dec 14.

Department of Conservative Dentistry and Endodontics, Meenakshi Academy of Higher Education and Research (MAHER), Faculty of Dentistry, Maduravoyal, Chennai, 600095, India.

Objective: The purpose of the present study was to evaluate the effect of Endo-Ice followed by intrapulpal ice application for reducing pain during pulp extirpation in mandibular molars with symptomatic irreversible pulpitis.

Materials And Methods: Sixty patients diagnosed with symptomatic irreversible pulpitis participated in the present study. Subjects were randomly allocated to any one of the following groups: control group-inferior alveolar nerve block with lignocaine (2%) adrenaline (1:80000), articaine group-inferior alveolar nerve block with lignocaine (2%) adrenaline (1:80000) + Buccal infiltration with articaine (4%) with adrenaline (1:100000); or cold group-inferior alveolar nerve block with lignocaine (2%) adrenaline (1:80000) + cold application. Read More

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December 2018

Effectiveness of cognitive-behavioural therapy: a protocol for an overview of systematic reviews and meta-analyses.

BMJ Open 2018 Dec 14;8(12):e025761. Epub 2018 Dec 14.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Introduction: Cognitive-behavioural therapy (CBT) is a psychological therapy that has been used to improve patient well-being across multiple mental and physical health problems. Its effectiveness has been examined in thousands of randomised control trials that have been synthesised into hundreds of systematic reviews. The aim of this overview is to map, synthesise and assess the reliability of evidence generated from these systematic reviews of the effectiveness of CBT across all health conditions, patient groups and settings. Read More

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December 2018

Study protocol for a randomised controlled trial of humanoid robot-based distraction for venipuncture pain in children.

BMJ Open 2018 Dec 14;8(12):e023366. Epub 2018 Dec 14.

Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Introduction: Intravenous insertion (IVI) is a very common procedure in the emergency department (ED). IVI is often painful and stressful for both children and their families. Currently, distraction therapy is not used as a standard of care for IVI in North America. Read More

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December 2018

Effects of positive and negative expectations on human pain perception engage separate but interrelated and dependently regulated cerebral mechanisms.

J Neurosci 2018 Dec 14. Epub 2018 Dec 14.

Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan.

Expectations substantially influence pain perception, but the relationship between positive and negative expectations remains unclear. Recent evidence indicates that the integration between pain-related expectations and prediction errors is crucial for pain perception, which suggests that aversive prediction error-associated regions, such as the anterior insular cortex (aIC) and rostral anterior cingulate cortex (rACC), may play a pivotal role in expectation-induced pain modulation and help to delineate the relationship between positive and negative expectations. In a stimulus expectancy paradigm combining fMRI in healthy volunteers of both sexes, we found that, although positive and negative expectations respectively engaged the right aIC and right rACC to modulate pain, their associated activations and pain rating changes were significantly correlated. Read More

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December 2018

Loss of adult 5-HT1A autoreceptors results in a paradoxical anxiogenic response to antidepressant treatment.

J Neurosci 2018 Dec 14. Epub 2018 Dec 14.

Ottawa Hospital Research Institute (Neuroscience), Ottawa, Canada

Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are first-line antidepressants, but require several weeks to elicit their actions. Chronic SSRI treatment induces desensitization of 5-HT1A autoreceptors to enhance 5-HT neurotransmission. Mice (both sexes) with gene deletion of 5-HT1A autoreceptors in adult 5-HT neurons (1AcKO) were tested for response to SSRIs. Read More

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December 2018

Use of Mobile Devices to Help Cancer Patients Meet Their Information Needs in Non-Inpatient Settings: Systematic Review.

JMIR Mhealth Uhealth 2018 Dec 14;6(12):e10026. Epub 2018 Dec 14.

Division of Population Medicine, Cardiff University, Cardiff, United Kingdom.

Background: The shift from inpatient to outpatient cancer care means that patients are now required to manage their condition at home, away from regular supervision by clinicians. Subsequently, research has consistently reported that many patients with cancer have unmet information needs during their illness. Mobile devices, such as mobile phones and tablet computers, provide an opportunity to deliver information to patients remotely. Read More

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December 2018

Supported Internet-Delivered Cognitive Behavioral Therapy Programs for Depression, Anxiety, and Stress in University Students: Open, Non-Randomised Trial of Acceptability, Effectiveness, and Satisfaction.

JMIR Ment Health 2018 Dec 14;5(4):e11467. Epub 2018 Dec 14.

Department of Psychology, University of Minnesota, Minneapolis, MN, United States.

Background: Many university campuses have limited mental health services that cannot cope with the high demand. One alternative is to use internet-delivered cognitive behavioral therapy (iCBT) as a way of tackling barriers such as lack of availability and scheduling issues.

Objective: This study aimed to assess feasibility, acceptability, effectiveness, and satisfaction of a supported iCBT intervention offering 3 programs on depression, anxiety, and stress to university students. Read More

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December 2018

The influence of mental health on Patient-Reported Outcomes Measurement Information System (PROMIS) and traditional outcome instruments in patients with symptomatic glenohumeral arthritis.

J Shoulder Elbow Surg 2018 Dec 12. Epub 2018 Dec 12.

Department of Orthopaedic Surgery, Washington University in St Louis, St Louis, MO, USA.

Background: The Patient-Reported Outcomes Measurement Information System (PROMIS) assessment includes computerized adaptive tests (CATs) that assess function, pain, depression, and anxiety. The influence of mental health on patients' self-reported pain and function has not been explored using PROMIS in patients with symptomatic glenohumeral osteoarthritis.

Methods: This cross-sectional study included 284 shoulders in 276 patients presenting with isolated glenohumeral osteoarthritis. Read More

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December 2018

Providing mindfulness meditation for patients with depression and anxiety in a community pharmacy: A pilot study.

J Am Pharm Assoc (2003) 2018 Dec 11. Epub 2018 Dec 11.

Objective: The objective of this study was to assess the impact of mindfulness meditation offered in a community pharmacy on patients with current anxiety or a history of anxiety, depression, or both.

Setting: Community pharmacy clinical space located in a grocery store.

Practice Description: An 8-week, once-per-week mindfulness meditation program for patients with anxiety or depression. Read More

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December 2018

Patient and provider characteristics associated with communication about opioids: An observational study.

Patient Educ Couns 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Regenstrief Institute, Inc., Indianapolis, IN, USA; Department of Communication Studies, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA; Center for Health Information and Communication, Roudebush Veterans Affairs Medical Center, Indianapolis, IN, USA.

Objective: Our objective is to examine the relationship of patient and provider characteristics and communication with chronic non-cancer pain and opioid management in primary care.

Method: We conducted an observational study using audio-recorded primary care appointments (up to 3/patient) and self-reported assessments of primary care providers (PCPs) and patients. We coded visit transcripts for 1) opioid and pain management talk and 2) mental health and opioid safety talk. Read More

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December 2018

Aphrodisiac effect of Hunteria umbellata seed extract: Modulation of nitric oxide level and arginase activity in vivo.

Pathophysiology 2018 Dec 5. Epub 2018 Dec 5.

Functional Foods and Nutraceutical Research Unit, Department of Biochemistry, Federal University of Technology, P.M.B. 704, Akure, 340001, Nigeria.

Hunteria umbellata has been reported useful in managing the male sexual related disorder, but there is a dearth of information on its possible mechanism of action. Hence, this study was designed to investigate the effect of H. umbellata on some sexual behavior parameters in male rats, in order to ascertain its acclaimed aphrodisiac property. Read More

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December 2018

Βeta-sitosterol enhances motor coordination, attenuates memory loss and demyelination in a vanadium-induced model of experimental neurotoxicity.

Pathophysiology 2018 Dec 5. Epub 2018 Dec 5.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, China.

Environmental discharge of vanadium causes cognitive and behavioral impairments in humans and animals via production of reactive oxygen species leading to lipid peroxidation and alteration in antioxidant defence system. The current study was carried out to investigate the cognitive-enhancing ability of β-sitosterol in vanadium-induced neurotoxicity. Forty eight mice were randomly assigned into 4 groups (A-D) with the following treatments: group A; distilled water, B; α-tocopherol + sodium metavanadate (NaOV), C; β-sitosterol + NaOV and D; only NaOV. Read More

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December 2018

[Exploring illness perceptions of lupus patients for a motivational environment in therapeutic education].

Rev Med Interne 2018 Dec 11. Epub 2018 Dec 11.

Service de médecine interne, Centre de référence des maladies auto-immunes systémiques rares, hôpital Huriez, CHU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France.

Purpose: Therapeutic education (TE) intends to help patients with systemic lupus erythematosus to better understand their disease and to improve their quality of life. The objective of this study was to assess illness perceptions of the person to provide a motivational environment for TE.

Methods: Systemic lupus erythematosus patients followed in the department of internal medicine in Lille university hospital responded to a questionnaire assessing five dimensions of the person as proposed by Giordan: the cognitive (knowledge), perceptual (fatigue and pain), affective (anxious and depressive symptoms), infra-cognitive (intimate reasoning) and metacognitive (worldview) dimensions. Read More

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December 2018

Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation.

Int J Mol Sci 2018 Dec 13;19(12). Epub 2018 Dec 13.

Department of Chemistry, Chung Yuan Christian University, Chung-Li 32023, Taiwan.

Leptin, a hormone secreted by peripheral adipose tissues, regulates the appetite in animals. Recently, evidence has shown that leptin also plays roles in behavioral response in addition to controlling appetite. In this study, we examined the potential function of leptin on non-appetite behaviors in zebrafish model. Read More

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December 2018
2.862 Impact Factor

Examining the Association and Directionality between Mental Health Disorders and Substance Use among Adolescents and Young Adults in the U.S. and Canada-A Systematic Review and Meta-Analysis.

J Clin Med 2018 Dec 13;7(12). Epub 2018 Dec 13.

School of Public Health, University of Saskatchewan, Saskatoon, SK S7N 2Z4, Canada.

Background: The purpose of this systematic review was to examine the association and directionality between mental health disorders and substance use among adolescents and young adults in the U.S. and Canada. Read More

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December 2018

Involvement of opioid system in behavioral despair induced by social isolation stress in mice.

Biomed Pharmacother 2019 Jan 5;109:938-944. Epub 2018 Nov 5.

Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Social isolation stress (SIS) as a type of chronic stress could induce depressive- and anxiety-like behaviors. Our study evaluates the role of opioid system on negative behavioral impacts of SIS in male NMRI mice. We investigated effects of morphine, a nonselective opioid receptor (OR) agonist, naltrexone (NLX), an OR antagonist, naltrindole (NLT), a delta opioid receptor (DOR) antagonist, SNC80, a DOR agonist, U-69593, a kappa opioid receptor (KOR) agonist, nor-Binaltorphimine, a selective KOR antagonist and cyprodime hydrochloride a selective mu opioid receptor (MOR) antagonist on depressive- and anxiety-like behaviors. Read More

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January 2019

Chrysin (5,7-dihydroxyflavone) exerts anxiolytic-like effects through GABA receptors in a surgical menopause model in rats.

Biomed Pharmacother 2019 Jan 30;109:2387-2395. Epub 2018 Nov 30.

Facultad de Ciencias Químicas, Universidad Veracruzana, Orizaba, Veracruz, Mexico.

The present study investigated the effects of the flavonoid chrysin (5,7-dihydroxyflavone) on anxiety-like behavior in rats in a model of surgical menopause and evaluated the participation of γ-aminobutyric acid-A (GABA) receptors in these actions. At 12 weeks post-ovariectomy, the effects of different doses of chrysin (0.5, 1, 2, and 4 mg/kg) were evaluated in the elevated plus maze, light/dark test, and locomotor activity test, and comparisons were made with the clinically effective anxiolytic diazepam. Read More

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January 2019

Pharmacogenomic assessment of herbal drugs in affective disorders.

Biomed Pharmacother 2019 Jan 6;109:1148-1162. Epub 2018 Nov 6.

Sunandan Divatia School of Science, NMIMS (Deemed-to-be University), Vile Parle (W), Mumbai, 400 056, Maharashtra, India. Electronic address:

Anxiety and depression, the most prevalent psychiatric disorders are co-morbid in nature affecting several people across the world. There is an increase in demand for complementary and alternative medicines, specifically herbal botanicals due to various side effects exhibited by conventional drugs. Herbal drugs mentioned in traditional medicines, face acceptance issues by the medical community due to lack of scientific data regarding their neurochemical pathways. Read More

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January 2019

Psychological and electrophysiological indices of inattention in hoarding.

Psychiatry Res 2018 Dec 5;270:915-921. Epub 2018 Nov 5.

School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia.

Individuals with elevated hoarding symptoms report elevated symptoms of ADHD and these symptoms are related to impaired daily functioning. Neuropsychological studies have found specific deficits in attention, and a recent review of attentional data from numerous hoarding studies concluded that inattention likely represents an etiological factor in hoarding, rather than a comorbidity. Our study aimed to examine which symptoms of ADHD, inattention or hyperactivity, are related to hoarding symptom severity, and whether individuals with hoarding symptoms display a neurophysiological marker of poor attention (Theta/Beta Ratio; THBR) that might explain these associations. Read More

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December 2018

The association between schizotypal traits and social functioning in adolescents from the general population.

Psychiatry Res 2018 Dec 5;270:895-900. Epub 2018 Nov 5.

Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.

Difficulties in social functioning have been linked to schizotypy, which may reflect vulnerability to psychotic disorders. We investigated these links in early adolescence, a developmental stage when many mental illnesses first emerge. Using the Strength and Difficulties Questionnaire and The Community Assessment of Psychic Experiences, we examined the association of peer-relationship problems and prosocial behavior with positive and negative schizotypy in a sample of 149 school children (70 girls, 79 boys) between 12 and 15 years old. Read More

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December 2018

Assessment of perceived mental health-related stigma: The Stigma-9 Questionnaire (STIG-9).

Psychiatry Res 2018 Dec 10;270:822-830. Epub 2018 Oct 10.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf, Germany. Electronic address:

Mental health-related stigma is common and inhibits help-seeking. It triggers fears of devaluation and can add to the burden of a mental disorder. To counter the consequences of mental health-related stigma, its sound assessment is crucial. Read More

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December 2018

The spark that might have ignited the fire: The association of cognitive and psychological factors with state anxiety in light of the Syrian-Israeli incident.

Psychiatry Res 2018 Dec 28;270:815-821. Epub 2018 Oct 28.

School of Social Work, Ariel University, Ariel, 40700, Israel. Electronic address:

The current study aimed to explore Israelis' state anxiety due to a Syrian-Israeli incident that occurred on February 10, 2018, when an Israeli F-16 fighter jet was shot down by Syrian air defense forces. In line with the "looming vulnerability" model which emphasizes the importance of the dynamic nature of psychologically threatening situations, the following psychological factors were suggested: associative memory of prior events, worries of future war, sense of safety, and death anxiety. We employed two cross-sectional points of time in our assessment: 36 hours and three months after the incident. Read More

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December 2018

Comorbidity of Attention Deficit Hyperactivity Disorder and Generalized Anxiety Disorder in children and adolescents.

Psychiatry Res 2018 Dec 31;270:780-785. Epub 2018 Oct 31.

Department of Human Sciences, Roma Tre University, Rome, Italy.

The aim of the study is to explore the impact of Generalized Anxiety Disorder (GAD) comorbidity in children with Attention Deficit Hyperactivity Disorder (ADHD). Six hundred children with ADHD (mean age = 9.12 years), recruited from 2013 to 2017, participated in the study. Read More

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December 2018

Impact of physical or sexual childhood abuse on plasma DHEA, DHEA-S and cortisol in a low-dose dexamethasone suppression test and on cardiovascular risk parameters in adult patients with major depression or anxiety disorders.

Psychiatry Res 2018 Dec 26;270:744-748. Epub 2018 Oct 26.

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.

While the impact of childhood trauma on basal and dynamic cortisol regulation has widely been studied, the most abundant steroid hormones dehydroepiandrosterone (DHEA) and its sulphated derivative DHEA-S have received little attention in this context. One-hundred in-door patients suffering from major depression or an anxiety disorder filled in the Childhood Trauma Questionaire. A low dose dexamethasone suppression test (DST) measuring DHEA, DHEA-S and cortisol was performed. Read More

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December 2018

On continuum beliefs and psychiatric stigma: Similarity to a person with schizophrenia can feel too close for comfort.

Psychiatry Res 2018 Dec 27;270:731-737. Epub 2018 Oct 27.

Psychology Department, St. John Fisher College, Rochester, NY, USA.

Continuum belief interventions that blur boundaries between "normal" individuals and individuals with psychiatric problems have shown promise in reducing psychiatric stigma. Interventions to date have afforded participants considerable psychological distance from individuals with mental illness. An intervention that compels psychological closeness to individuals with mental illness may lead to increased anxiety/threat and an attenuated intervention effect on stigma. Read More

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December 2018

Sex differences in an old adult sample with substance use disorder: A 6 months follow-up study.

Psychiatry Res 2018 Dec 16;270:1157-1165. Epub 2018 Oct 16.

Addiction and Dual Diagnosis Unit, Vall Hebron University Hospital, Barcelona, Spain; Psychiatry Service, CIBERSAM, Vall Hebron University Hospital, Barcelona, Spain; Autonomous University of Barcelona, Barcelona, Spain.

Substance use disorder (SUD) is a worldwide concern that has its own particularities regarding age and sex. This study aims to assess the differences between old SUD women and men regarding socio-demographics, clinical factors and outcomes. A 6-months follow-up longitudinal study was conducted in an outpatient center, on a convenience sample of 115 SUD old adults (≥65 years old, average age of 71. Read More

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December 2018

Male Caregivers of Persons with End Stage Renal Disease: A Literature Review.

Nephrol Nurs J 2016 Nov-Dec;43(6):495-519

Professor, Biostatistics & Epidemiology, University of Tennessee Health Science Center, Memphis, TN.

This literature review examined burden, depressive symptoms, and perceived health reported by male caregivers of persons with end stage renal disease. These studies suggest that male caregivers often experience negative outcomes. Compared to non-caregivers, male caregivers had higher levels of anxiety and depressive symptoms. Read More

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December 2018

Urological surgery in elderly and the perioperative management.

Nihon Rinsho 2017 Apr;75(4):543-547

Perioperative delirium and depression are characteristic of in elderly patients undergoing urological operation. The treatment for urological disease is stagnant, exchanged or inter- rupted by these complications. Furthermore, these complications may course to other more complications. Read More

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A total health economy approach to revalidation.

Nurs Times 2016 Aug;112(27-28):12-14

Revalidation has been a source of anxiety and uncertainty for some nurses and midwives. With a mixed health economy including private and public sector organisations, the Bailiwick of Guernsey wanted to ensure the system was implemented consistently. A programme of training was developed to help staff through the revalidation process and link the Nursing and Midwifery Council's Code of Conduct to practice. Read More

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Repetitive negative thinking as a mediator in prospective cross-disorder associations between anxiety and depression disorders and their symptoms.

J Behav Ther Exp Psychiatry 2018 Nov 29;63:6-11. Epub 2018 Nov 29.

VU University Medical Center, Department of Psychiatry, Amsterdam, the Netherlands.

Background And Objectives: Comorbidity among anxiety and depression disorders and their symptoms is high. Rumination and worry have been found to mediate prospective cross-disorder relations between anxiety and depression disorders and their symptoms in adolescents and adults. We examined whether generic repetitive negative thinking (RNT), that is content- and disorder-independent, also mediates prospective cross-disorder associations between anxiety and depressions disorders and their symptoms. Read More

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November 2018
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Which patients initiate cognitive processing therapy and prolonged exposure in department of veterans affairs PTSD clinics?

J Anxiety Disord 2018 Nov 20;62:53-60. Epub 2018 Nov 20.

Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Department of Medicine, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA; Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454, USA; Department of Psychology, University of Minnesota, 75 E River Rd, Minneapolis, MN 55455, USA. Electronic address:

The United States Department of Veterans Affairs (VA) provides Cognitive Processing Therapy (CPT) and Prolonged Exposure therapy (PE) for PTSD at all of its facilities, but little is known about systematic differences between patients who do and do not initiate these treatments. VA administrative data were analyzed for 6,251 veterans receiving psychotherapy over one year in posttraumatic stress disorder (PTSD) specialty clinics at nine VA medical centers. CPT and PE were initiated by 2,173 (35%) patients. Read More

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November 2018

The T-type calcium channel antagonist, Z944, alters social behavior in Genetic Absence Epilepsy Rats from Strasbourg.

Behav Brain Res 2018 Dec 11. Epub 2018 Dec 11.

University of Saskatchewan, Department of Physiology, Saskatoon, SK, Canada.

Abnormalities in social behavior are a co-morbid symptom of idiopathic generalized epilepsies such as childhood absence epilepsy. The Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model is a spontaneously occurring absence epilepsy phenotype closely correlated to that of human absence epilepsies. Similar to the human conditions, GAERS display social abnormalities. Read More

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December 2018

Chronic Adolescent Stress Sex-Specifically Alters Central and Peripheral Neuro-Immune Reactivity in Rats.

Brain Behav Immun 2018 Dec 11. Epub 2018 Dec 11.

Virginia Commonwealth University, Department of Anatomy & Neurobiology, United States. Electronic address:

Adversity during development is a reliable predictor of psychiatric disorders such as depression and anxiety which are increasingly recognized to have an immune component. We have previously demonstrated that chronic adolescent stress (CAS) in rats leads to depressive-like behavior in adulthood along with long-lasting changes to the hypothalamic-pituitary-adrenal axis and pro-inflammatory cytokine induction in the hippocampus. However, the mechanisms by which CAS promotes hippocampal inflammation are not yet defined. Read More

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December 2018

Relationships between Financial Toxicity and Symptom Burden in Cancer Survivors: A Systematic Review.

J Pain Symptom Manage 2018 Dec 11. Epub 2018 Dec 11.

School of Nursing, Queensland University of Technology, Kelvin Grove, Q4059, Australia; Department of Physiological Nursing, University of California, San Francisco, 2 Koret Way - N631Y, San Francisco, CA 94143-0610.

Context: Financial toxicity (FT) is used to describe the financial distress/hardship associated with cancer and its treatment.

Objectives: The aim of this review was to explore the relationship between FT and symptom burden.

Method: A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Read More

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December 2018
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Internet-based cognitive and behavioural therapies for post-traumatic stress disorder (PTSD) in adults.

Cochrane Database Syst Rev 2018 Dec 14;12:CD011710. Epub 2018 Dec 14.

Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Hadyn Ellis Building, Maindy Road, Cardiff, UK, CF24 4HQ.

Background: Therapist-delivered trauma-focused psychological therapies are an effective treatment for post-traumatic stress disorder (PTSD). These have become the accepted first-line treatments for the disorder. Despite the established evidence-base for these therapies, they are not always widely available or accessible. Read More

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December 2018

Grit is associated with lower level of depression and anxiety among university students in Chiang Mai, Thailand: A cross-sectional study.

PLoS One 2018 14;13(12):e0209121. Epub 2018 Dec 14.

Department of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.

Background: Depression and anxiety symptoms are prevalent among university students in both developed and developing settings. Recently, grit, defined as perseverance and passion for long-term goals, has emerged as an indicator of success and well-being. However, the relationship between grit and poor mental health outcomes among university students is largely unknown. Read More

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December 2018
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CE: Addressing Food Insecurity in Vulnerable Populations.

Am J Nurs 2018 Dec 12. Epub 2018 Dec 12.

Heather L. Flores is an NP at the John and Ella Byrd McCain Health and Counseling Center, Alabama A&M University, Huntsville. Azita Amiri is an assistant professor of nursing at the University of Alabama, Huntsville. Contact author: Heather L. Flores, The authors and planners have disclosed no potential conflicts of interest, financial or otherwise.

A review of risk factors, health effects, screening, and resources. ABSTRACT: Food insecurity affects people of all ages, in every area in which nurses work or volunteer. The U. Read More

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December 2018
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Use of Buprenorphine-Naloxone in the Treatment of Tianeptine Use Disorder.

J Addict Med 2018 Dec 13. Epub 2018 Dec 13.

Spectrum Health, Center for Integrative Medicine, Grand Rapids, MI (PT); Boston University Department of Medicine, Section of General Internal Medicine, Clinical Addiction Research and Education Unit, School of Medicine & Boston Medical Center, Boston, MA (AYW).

: Tianeptine is an atypical antidepressant which exerts an opioid-like effect on the μ-opioid receptor. There is well documented intentional misuse and addiction to tianeptine in Europe, and this is increasingly being seen in the United States. We presented a case of buprenorphine/naloxone successfully being used to aid in cessation and subsequent abstinence from tianeptine after years of use. Read More

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December 2018

Prevention of anxiety and depression in school children: Effectiveness of the transdiagnostic EMOTION program.

J Consult Clin Psychol 2018 Dec 13. Epub 2018 Dec 13.

Centre for Child and Adolescent Mental Health, Eastern and Southern Norway.

Objective: The objective of the study was to examine the effectiveness of a transdiagnostic program (EMOTION, Coping Kids Managing Anxiety and Depression) targeting symptoms of anxiety and depression in schoolchildren by comparing the intervention condition (EC) to a control condition (CC).

Method: A clustered randomized design was used with schools as the unit of randomization. Children ( = 1686) aged 8-12 years in 36 schools completed screening using the Multidimensional Anxiety Scale (MASC-Child) and The Mood and Feelings Questionnaire Short version (SMFQ-Child). Read More

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December 2018

[Cartilaginous tumours].

Rev Med Suisse 2018 Dec;14(631):2259-2263

Service d'orthopédie et traumatologie de l'appareil moteur, HUG, 1211 Genève 14.

Cartilaginous tumours are rare and often incidentally discovered on imaging. They can also be responsible for osteoarticular symptoms (pain, joint stiffness, deformity or fracture) and will require a clinical, radiological and a histopathological assessment. Depending on the lesion, the management may consist of observation or a complex surgical procedure that will take place after a multidisciplinary discussion including the radiologist, the pathologist and the orthopaedic surgeon. Read More

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December 2018

Tokenism or true partnership: Parental involvement in a child's acute pain care.

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

University of Huddersfield.

Aims: To explore parental involvement in the child's acute pain care and establish ways in which parental preferences for involvement in their child's care can be identified, facilitated and enhanced by nurses.

Background: Despite growing evidence supporting effective acute pain management in children and the availability of national and international practice guidelines, children still experience acute pain. Involving parents in their child's pain care has been identified as being a central tenet of pain management in children. Read More

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December 2018
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