264,198 results match your criteria Anxiety


Differential item functioning of the Beck Anxiety Inventory in a rural, multi-ethnic cohort.

J Affect Disord 2021 Jun 12;293:36-42. Epub 2021 Jun 12.

University of Houston, Department of Psychology, Houston, TX, USA. Electronic address:

Background: Evaluating measurement bias is vital to ensure equivalent assessment across diverse groups. One approach for evaluating test bias, differential item functioning (DIF), assesses item-level bias across specified groups by comparing item-level responses between groups that have the same overall score. Previous DIF studies of the Beck Anxiety Inventory (BAI) have only assessed bias across age, sex, and disease duration in monolingual samples. Read More

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Effect of aromatherapy on sleep quality of adults and elderly people: A systematic literature review and meta-analysis.

Complement Ther Med 2021 Jun 21;60:102739. Epub 2021 Jun 21.

Department of Nursing Science, College of Medicine, Chungbuk National University, 1, Chungdae-ro, Seowon-gu, Cheonju-si, Chungcheongbuk-do, 28644, Republic of Korea. Electronic address:

Purpose: The purpose of this study was to characterize studies on aromatherapy and sleep quality and to identify the measurable effects of aromatherapy on the sleep quality of adults and elderly people.

Methods: We searched eight electronic databases for relevant studies published between January 2011 and December 2019 using the medical subheadings, "adult or elderly," "aromatherapy or aroma intervention," and "sleep quality or sleep satisfaction." Statistical analyses of the combined effect sizes, homogeneity, heterogeneity, and trim-and-fill method were performed using MIX 2. Read More

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Delineating sociodemographic, medical and quality of life factors associated with psychological distress in individuals with endometriosis.

Hum Reprod 2021 Jun 24. Epub 2021 Jun 24.

Department of Obstetrics and Gynaecology, The University of Sydney, Sydney, NSW, Australia.

Study Question: What is the relationship between specific quality of life domains and depression, anxiety and stress in the endometriosis population?

Summary Answer: Psychosocial domains of quality of life, such as a perception of social support and self-image, are more strongly associated with depression, anxiety and stress than pain and medical factors.

What Is Known Already: Prior research indicates a high prevalence of anxiety and depression in individuals with endometriosis. Pain is thought to be critical in the development of psychological distress, however prior research has investigated this association without consideration of psychosocial quality of life domains such as social functioning, perceived social support and self-image. Read More

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The effect of mental health on sleep quality of front-line medical staff during the COVID-19 outbreak in China: A cross-sectional study.

PLoS One 2021 24;16(6):e0253753. Epub 2021 Jun 24.

West China School of Nursing, Sichuan University/Department of Mental Health Centre, West China Hospital, Sichuan University, Chengdu, PR China.

Background: The 2019 coronavirus disease (COVID-19) pandemic is a public health emergency of international concern and poses a challenge to the mental health and sleep quality of front-line medical staff (FMS). The aim of this study was to investigate the sleep quality of FMS during the COVID-19 outbreak in China and analyze the relationship between mental health and sleep quality of FMS.

Methods: From February 24, 2020 to March 22, 2020, a cross-sectional study was performed with 543 FMS from a medical center in Western China. Read More

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Age as a determining variable in the practice or abandonment of physical exercise among young people.

PLoS One 2021 24;16(6):e0253750. Epub 2021 Jun 24.

Department of Specific Didactics, University of Vigo, Vigo, Spain.

Background: Numerous studies have reported a gradual decline in the practice of physical exercise with age, confirming high dropout rates in the adolescent period. The aim of this study was to investigate the motivation or barriers that lead to greater or lesser adherence to physical exercise among children and adolescents.

Methods: In this study, 1,081 individuals volunteered to participate [239 children (age: 10. Read More

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Mechanisms of parental distress during and after the first COVID-19 lockdown phase: A two-wave longitudinal study.

PLoS One 2021 24;16(6):e0253087. Epub 2021 Jun 24.

Department of Psychology, University of Oslo, Oslo, Norway.

Background: In these unpredictable times of the global coronavirus disease 2019 (COVID-19) pandemic, parents worldwide are affected by the stress and strain caused by the physical distancing protocols that have been put in place.

Objective: In a two-wave longitudinal survey, we investigated the levels of parental stress and symptoms of anxiety and depression in a sample of parents at two time points; during the implementation of the strictest physical distancing protocols following the onset of the COVID-19 pandemic (T1, N = 2,868) and three months after the discontinuation of the protocols (T2, N = 1,489). Further, we investigated the relationships between parental stress and anxiety and depression relative to relationship quality and anger toward their children at the two aforementioned time points, including subgroups based on age, parental role, cultural background, relationship status, education level, number of children, employment status and pre-existing psychiatric diagnosis. Read More

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A preliminary study on assessment of wellbeing among veterinary medical house officers.

PLoS One 2021 24;16(6):e0253111. Epub 2021 Jun 24.

Dean's Office, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.

Mental wellness is an important topic among practicing veterinarians. Peer reviewed studies focusing on veterinary house officers' wellbeing are lacking in veterinary medicine. The aim of this study was to assess wellbeing of house officers using validated surveys for anxiety, burnout, depression, and quality of life. Read More

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Ayahuasca Improves Self-perception of Speech Performance in Subjects With Social Anxiety Disorder: A Pilot, Proof-of-Concept, Randomized, Placebo-Controlled Trial.

J Clin Psychopharmacol 2021 Jun 20. Epub 2021 Jun 20.

From the Department of Neurosciences and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto National Institute of Science and Technology-Translational Medicine, Ribeirão Preto, Brazil ICEERS Foundation, International Center for Ethnobotanical Education, Research and Services, Barcelona Medical Anthopology Research Center, Universitat Rovira i Virgili, Tarragona, Spain School of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil.

Background: Ayahuasca is a classic hallucinogen with anxiolytic and antidepressive properties. Anecdotal evidence also suggests that it improves performance (eg, singing, speech). This controlled trial assessed the effects of ayahuasca on speech performance and anxiety in individuals with social anxiety disorder. Read More

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Psychometric Evaluation of the Korean Version of Control Attitudes Scale-Revised.

J Cardiovasc Nurs 2021 Jun 22. Epub 2021 Jun 22.

Kyoung Suk Lee, PhD, RN, MPH Associate Professor, College of Nursing, The Research Institute of Nursing Science, Seoul, Republic of Korea; ORCID: https://orcid.org/0000-0002-5083-3743 Da-In Park, PhD, RN Assistant Professor, Department of Nursing, College of Life Science and Nano Technology, Hannam University, Daejeon, Republic of Korea; ORCID: https://orcid.org/0000-0002-4738-5046.

Background: Heart failure (HF) is a chronic heart condition that requires patients to adapt to the disease and maintain a high degree of self-management. Patients with HF commonly feel loss of control, which has a negative effect on their compliance to self-care, health-related quality of life, and health outcomes. To promote self-care behavior and to develop healthy coping mechanisms, it is important to understand individual HF patients' perceived control, a self-generated belief that one has the ability to bring forth desired outcomes. Read More

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Long-Term Functional Outcome and Quality of Life Following In-Hospital Cardiac Arrest-A Longitudinal Cohort Study.

Crit Care Med 2021 Jun 24. Epub 2021 Jun 24.

Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia. Department of Physiotherapy, St. Vincent's Hospital, Melbourne, VIC, Australia. Department of Intensive Care, The Austin Hospital, Melbourne, VIC, Australia. Department of Physiotherapy, The Alfred Hospital, Melbourne,VIC, Australia.

Objectives: To evaluate the functional outcome and health-related quality of life of in-hospital cardiac arrest survivors at 6 and 12 months.

Design: A longitudinal cohort study.

Setting: Seven metropolitan hospitals in Australia. Read More

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Effectiveness of the Weighted Blanket With Psychiatric Patients in the Emergency Department: A Pilot Study.

J Am Psychiatr Nurses Assoc 2021 Jun 24:10783903211026740. Epub 2021 Jun 24.

Melvin Swanson, BS, PhD, East Carolina University College of Nursing, Greenville, NC, USA.

Background: Restraint and seclusion continue to be used with patients demonstrating aggressive and violent behaviors while in the emergency department and as inpatients in behavioral health (BH) units. The use of sensory interventions such as the weighted blanket (WB) is garnering interest as alternatives to aid in managing anxiety, anger, and aggressive behaviors. Reports of the effectiveness of the WB have primarily been anecdotal, and results of research with children have been mixed. Read More

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Mental Stress, Anxiety and Depressive Symptoms and Interleuken-6 Level among Healthcare Workers during the COVID-19 Pandemic.

J Prim Care Community Health 2021 Jan-Dec;12:21501327211027432

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

Objectives: This study aimed to evaluate the interleukin-6 (IL-6) levels and its relationship to stress, anxiety, and depressive symptoms among healthcare workers (HCWs) compared to controls during the COVID-19 pandemic.

Methods: A total of 80 HCWs in Suez Canal University Hospital in Ismailia, Egypt, and 80 controls were analyzed during the COVID-19 pandemic. The Depression, Anxiety and Stress Scale (DASS 21) questionnaire was used, and serum IL-6 level was determined in both groups. Read More

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Effect of COVID-19 pandemic on mental health among Bangladeshi healthcare professionals: A cross-sectional study.

Sci Prog 2021 Apr-Jun;104(2):368504211026409

Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.

The COVID-19 has been spreading across the world since December 2019. The pandemic has created tremendous fear of death from infection and awful psychological pressure on healthcare professionals (HCPs). The measures of psychological effects of the COVID-19 outbreak on the Bangladeshi HCPs are unknown. Read More

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Inflammatory Markers Profile in Older Adolescents During Treatment with Selective Serotonin Reuptake Inhibitors.

J Child Adolesc Psychopharmacol 2021 Jun 24. Epub 2021 Jun 24.

Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

This study aimed to investigate the serum levels of inflammatory markers in adolescents with major depressive disorder (MDD) using selective serotonin reuptake inhibitors. This was an 8-month observational study, involving 30 adolescents with and 38 without (control) MDD diagnosis. Demographic (age and gender) and anthropometric data (weight, height, and calculated body mass index [BMI] score) were collected. Read More

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Lack of Associations Between C-Reactive Protein and Mood and Anxiety Symptoms in Adolescents.

J Child Adolesc Psychopharmacol 2021 Jun 24. Epub 2021 Jun 24.

Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA.

Increased peripheral inflammation has been consistently documented in both adult and pediatric depression. However, elevated levels of C-reactive protein (CRP), a nonspecific biomarker for inflammation, have been primarily reported in adults; whether CRP plays a similar role in adolescent depression has not been conclusively established. In our prior work, we identified relationships between CRP and reward neurocircuitry in adolescents with psychiatric symptoms ( = 64) but not with depressive symptoms. Read More

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Female adopted Chinese-American youth's sense of exclusion and short-and long-term adjustment.

Am J Orthopsychiatry 2021 Jun 24. Epub 2021 Jun 24.

Department of Sociology.

In this article, we tested if female adopted Chinese youth's sense of exclusion predicted their behavioral adjustment and mental disorder diagnoses concurrently (Study 1) and longitudinally 5 years later (Study 2). In Study 1, 224 adoptees ( = 13.6 years, = 2. Read More

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Telehealth cognitive behavioral therapy for depression in Parkinson's disease: A case study.

Psychotherapy (Chic) 2021 Jun 24. Epub 2021 Jun 24.

Department of Psychological and Brain Sciences.

Parkinson's disease (PD) is characterized as a motor disorder, but the majority of individuals with PD also suffer from nonmotor symptoms, including mental health difficulties, such as depression, anxiety, and apathy, as well as decreased cognitive function, daily function, sleep quality, and quality of life. Cognitive behavioral therapy (CBT) is an effective treatment for depression in PD, but motor disability, work schedule, transportation issues, and care partner burden may cause difficulty in attending weekly face-to-face therapy sessions. A promising avenue in the delivery of CBT is telehealth. Read More

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Conflict-coparenting spillover: The role of actors' and partners' attachment insecurity and gender.

J Fam Psychol 2021 Jun 24. Epub 2021 Jun 24.

School of Psychology.

The current research applied a dyadic perspective to examine by examining (a) whether actors' or partners' hostility during couples' conflict discussions predicted greater hostility in a subsequent play activity with their child and (b) whether these actor and partner effects were moderated by two factors that prior theory and research suggest may shape conflict-coparenting spillover: attachment insecurity and parent gender. Cohabiting or married couples were video recorded discussing their most serious conflict while their 4-5-year-old child was in a separate room ( = 94 families). Immediately following their conflict discussions, couples were reunited with their child to participate in a semistructured family activity. Read More

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Examining the joint development of antisocial behavior and personality: Predictors and trajectories of adolescent indirect aggression and machiavellianism.

Dev Psychol 2021 May;57(5):805-813

Counselling Psychology, Faculty of Education, University of Ottawa.

Indirect aggression has been associated with antisocial personality traits like Machiavellianism, but there is a lack of evidence on their longitudinal development across adolescence. Therefore, the joint developmental trajectories of adolescent indirect aggression and Machiavellianism across 3 years of high school (Grades 10 to 12) were investigated. Predictors of joint trajectory groups at the start of high school (Grade 9) were also explored. Read More

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The Role of Social Skills in Predicting Treatment-Recovery in Children with a Social Anxiety Disorder.

Res Child Adolesc Psychopathol 2021 Jun 24. Epub 2021 Jun 24.

Research Institute of Child Development and Education, University of Amsterdam, Amsterdam, The Netherlands.

The current study investigated the role of social skills and its interaction with social anxiety as predictors of treatment outcome in children with an anxiety disorder either with or without a social anxiety disorder (SoAD). In total, 133 children (aged 8 to 13) with an anxiety disorder received a 10-session cognitive behavioral treatment (FRIENDS program). Pre- to post treatment Reliable Change (RC) and Treatment-Recovery (TR) were assessed from a multi-informant perspective, by including diagnostic information (ADIS C/P), child-reported anxiety symptoms (MASC) and parent-reported internalizing symptoms (CBCL-Int). Read More

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Extreme Glycemic Fluctuations Debilitate NRG1, ErbB Receptors and Olig1 Function: Association with Regeneration, Cognition and Mood Alterations During Diabetes.

Mol Neurobiol 2021 Jun 24. Epub 2021 Jun 24.

Institute of Science, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, 382 481, Gujarat, India.

Neuronal regeneration is crucial for maintaining intact neural interactions for perpetuation of cognitive and emotional functioning. The NRG1-ErbB receptor signaling is a key pathway for regeneration in adult brain and also associated with learning and mood stabilization by modulating synaptic transmission. Extreme glycemic stress is known to affect NRG1-ErbB-mediated regeneration in brain; yet, it remains unclear how the ErbB receptor subtypes are differentially affected due to such metabolic variations. Read More

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Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts.

Neurochem Res 2021 Jun 24. Epub 2021 Jun 24.

NHC Key Laboratory of Diagnosis and Treatment On Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, 1 Yixueyuan Road, Yuzhong, Chongqing, 400016, China.

Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis of BoDV-1-infected hosts is unknown. We used lentivirus LV5-P40 overexpressing P40 to infect primary hippocampal neurons and characterized the interactome of P40 with co-immunoprecipitation (Co-IP) followed by mass spectrometry (MS) analysis. These interacting protein partners revealed the pathogenesis of BoDV-1-infected hosts. Read More

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Daily mindfulness training reduces negative impact of COVID-19 news exposure on affective well-being.

Psychol Res 2021 Jun 24. Epub 2021 Jun 24.

Department of Psychology, University of New Hampshire, 105 Main St, Durham, NH, USA.

COVID-19 has led to mental health adversities worldwide. The current study examined whether daily practice of brief mindfulness training has a beneficial impact on affective well-being, and mitigates the negative impact of exposure to COVID-19 news during the pandemic. Participants were randomly assigned into a mindfulness training (MT) group or a waitlist control (WC) group. Read More

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Revisiting the JOQUER trial: stratification of primary Sjögren's syndrome and the clinical and interferon response to hydroxychloroquine.

Rheumatol Int 2021 Jun 24. Epub 2021 Jun 24.

Musculoskeletal Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

To re-analyse the clinical outcomes and interferon (IFN) activity data from the JOQUER trial, a phase III trial investigating hydroxychloroquine (HCQ) in patients with primary Sjögren's syndrome (pSS), after stratifying patients into putative pathobiological subgroups utilizing the Newcastle Sjögren's Stratification Tool (NSST) based on patient-reported symptoms of dryness, pain, fatigue, anxiety and depression. 107 patients were assigned to one of four subgroups using NSST at baseline-the high symptom burden (HSB), pain dominant with fatigue (PDF), dryness dominant with fatigue (DDF) and low symptom burden (LSB). Endpoints were re-analysed after stratification, testing for treatment differences within subgroups and adjusting for baseline differences using a repeated measures covariate model. Read More

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Parkinson's disease: A current perspectives on Parkinson's disease and key bioactive natural compounds as future potential drug candidates.

Curr Drug Targets 2021 Jun 23. Epub 2021 Jun 23.

Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.

Parkinson's disease (PD) is one of the most common types of neurological disorder prevailing worldwide and is rapidly increasing in the elderly population across the globe. The cause of PD is still unknown, but a number of genetic as well as environmental factors contributing to the pathogenesis of Parkinson's disease have been identified. The hallmark of PD includes dopamine deficiency (neurotransmitter imbalance) due to the gradual loss of dopaminergic nerves in the substantia nigra in the midbrain. Read More

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Therapeutic effects of saffron extract on different memory types, anxiety, and hippocampal BDNF and TNF-α gene expressions in sub-chronically stressed rats.

Nutr Neurosci 2021 Jun 24:1-15. Epub 2021 Jun 24.

Medical Students' Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

While stress reportedly impairs memory, saffron enhances it. This study investigated the therapeutic effects of saffron extract on different memory types, anxiety-like behavior, and expressions of BDNF and TNF-α genes in sub-chronically stressed rats. Rats were randomly assigned to control, restraint stress (6 h/day/7 days), two 7-days saffron treatments with 30 and 60 mg/kg, and two stress-saffron groups (30 and 60 mg/kg/7 post-stress days). Read More

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