Antiviral Res 2022 Jun 8;202:105314. Epub 2022 Apr 8.
Department of Biochemistry and Molecular Biology, School of Medical Laboratory, Bengbu Medical College, Bengbu, Anhui Province 233030, People's Republic of China; Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, Anhui Province, 233030, People's Republic of China; Department of Basic Veterinary Medicine College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, 430070, People's Republic of China. Electronic address:
Porcine reproductive and respiratory syndrome (PRRS) is a pig disease caused by the PRRS virus (PRRSV) that is characterized with diffuse interstitial pneumonia and lung edema. High expressions of chemokine CXCL10 and its receptor CXCR3 are reported in infected porcine lungs. Since CXCR3 is a key player in host inflammatory response, it might be a therapeutic target to treat lung damage caused by PRRSV infection. Read More