11 results match your criteria Antibiotiques[Journal]

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[Characteristics of lower respiratory tract infections in the elderly].

Authors:
L Drieux

Antibiotiques (Paris) 2010 Dec 25;12(4):190-196. Epub 2010 Sep 25.

Équipe opérationnelle en hygiène hospitalière, hôpital Charles-Foix, AP-HP, 7, avenue de la République, 94200 Ivry-sur-Seine, France.

Pneumonia is more frequent among the elderly and is associated with higher rates of hospitalization and death. The diagnosis of pneumonia in the elderly is a clinical challenge because of its non-typical symptoms and because of a poor diagnostic yield of microbiological analysis. Ageing is associated with specific pathogenesis, modifications in lung performance and modifications in oropharyngeal flora. Read More

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December 2010

[CCR5 antagonists and HIV-1 infection: Bases and consequences of this therapeutic approach].

Antibiotiques (Paris) 2010 Mar 18;12(1):27-41. Epub 2010 Feb 18.

Faculté de médecine, université Montpellier 1, 2, rue École-de-Médecine, 34060 Montpellier cedex 2, France.

CCR5 molecule is a chemokine receptor with an important role in infectious diseases; not only is it the main coreceptor for HIV-1, but it has also been involved in the immune defense against various transmissible agents. CCR5 antagonists constitute a new class of antiretrovirals. Three molecules of this class have reached phases 2B and 3 of clinical development: aplaviroc (GlaxoSmithKine), vicriviroc (Schering-Plough) and maraviroc (Pfizer). Read More

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[Microbiological diagnosis: Etiologic driven and syndrome driven].

Authors:
F Gouriet D Raoult

Antibiotiques (Paris) 2009 Feb 29;11(1):37-48. Epub 2008 Nov 29.

Unité des rickettsies CNRS-IRD UMR 6236, faculté de médecine, université de la Méditerranée, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France.

Objectives: Over the past decade, the introduction of techniques of molecular biology and the automation have undergone important changes in the practice of clinical microbiological laboratories.

Methods: Commonly, physician prescriptions are etiology driven for emerging infectious agent. The improving in test standardization and rapidity and the best communication between physician and clinical microbiologist lead to profound changes in microbiology laboratories. Read More

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February 2009

[Epidemiologic characteristics and prevention of viral nosocomial infections].

Antibiotiques (Paris) 2009 Feb 29;11(1):29-36. Epub 2008 Nov 29.

Laboratoire de virologie, centre de biologie, CHU de Clermont-Ferrand, 63003 Clermont-Ferrand, France.

Objectives: To describe epidemiological features of viral nosocomial infections (VNI) and their prevention principles.

Epidemiology: Many factors lead to underestimate VNI: difficulty to distinguish between community-acquired and nosocomial infections for seasonal viral diseases, incubation time leading to symptoms after patient discharge, difficulty for diagnosis. Population at high risks of VNI are the children, the elderly and the immunocompromized patients. Read More

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February 2009

[Travelling epidemics].

Authors:
M Rey

Antibiotiques (Paris) 2007 Dec 3;9(4):226-232. Epub 2008 Jan 3.

Professeur honoraire à la Faculté de Médecine de Clermont-Ferrand (maladies infectieuses et tropicales).

Objectives: We have to become aware of the current development of international travels which has contributed to amplify circulation of all sorts of infectious agents. We will describe the current situation.

Observations: Infectious agents are carried by means of travellers, immigrants, as well as by animals, goods and merchandise. Read More

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December 2007

[Immunity and antiviral vaccinations. Example: the respiratory mucosa].

Antibiotiques (Paris) 2007 May 3;9(2):130-138. Epub 2008 Jan 3.

EA 3175 « Biologie Moléculaire et Cellulaire des Micro-organismes », Laboratoire de Bactériologie-Virologie-Hygiène, CHU Dupuytren, 2, avenue Martin Luther King, 87042 Limoges.

Objective: As the mucosal surfaces of the respiratory tract represent a major portal of entry for most human viruses and many bacteria, they seem to be a critical component of the mammalian immunologic repertoire. Thus, vaccines stimulating this local immunity could represent an interesting approach to prevent these infections. After detailing the different mechanisms implied in this mucosal immunity, the aim of this study is to analyze the basis of such a vaccination and the different vaccines available to mucosal respiratory tract use. Read More

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Rôle de la médecine interne face aux maladies infectieuses émergentes.

Authors:
Ph Renou

Antibiotiques (Paris) 2007 Feb 3;9(1):4-8. Epub 2008 Jan 3.

32 rue Beauverger, 72000 Le Mans.

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February 2007

[Infectious and non infectious factors in otitis media and in sinusitis].

Authors:
B Barry

Antibiotiques (Paris) 2005 Dec 3;7(4):219-223. Epub 2008 Jan 3.

Service ORL, Hôpital Bichat, 46, rue Henri Huchard, 75018 Paris.

Infections of the ENT area are frequent and otitis media in children, sinusitis in adults are generally attributed to viruses or bacterial species. However many non infectious factors play an important role and may lead to useless antibiotic treatments. In otitis media, several factors such as mechanical defect in Eustachian tube, immature immunity, passive tobacco environment are capable to initiate a first viral step of otitis media, followed by bacterial infection due to , . Read More

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December 2005

[Emergent viruses and/or repeated threats].

Authors:
B Lina

Antibiotiques (Paris) 2005 May 3;7(2):106-110. Epub 2008 Jan 3.

Laboratoire de Virologie Lyon Est, CNR des entérovirus & CNR des virus influenza région sud, UMR CNRS 5537, Domaine Rockefeller, 69373 Lyon cedex 08.

Emergent viruses have attracted attention during years 2003 and 2004. Ancient fears have reappeared regarding pathogenic agents, capable to result in epidemics with high mortality rates. Such events constitute really repeated threats. Read More

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Maladies exotiques : maladies émergentes du xx siècle.

Authors:
P Bourée

Antibiotiques (Paris) 2004 Dec 3;6(4):219-221. Epub 2008 Jan 3.

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December 2004

[Adenoviral respiratory diseases in healthy children: a study of 116 hospital cases].

Antibiotiques (Paris) 2004 May 3;6(2):97-102. Epub 2008 Jan 3.

Laboratoire de Virologie Humaine et Moléculaire, CHU de Caen avenue Georges Clémenceau, 14033 Caen cedex.

Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other diseases. Diagnosis may be difficult to achieve.The clinical findings for 116 children hospitalised with adenoviral infection were studied retrospectively. Read More

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