5 results match your criteria Anti-infective agents[Journal]

  • Page 1 of 1

Modeling and Statistical Optimization of Culture Conditions for Improvement of Antifungal Compounds Production by S19 Strain of Wastewater Origin.

Antiinfect Agents 2019 Apr;17(1):39-49

1Laboratoire de Microbiologie Appliquée, Département de Microbiologie, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000, Bejaia, Algérie; 2Laboratoire de Génie de l'environnement, Faculté de Technologie, Université de Bejaia, 06000, Bejaia, Algérie; 3Laboratoire de Biochimie, Biophysique, Biomathématiques et Scientometries (L3BS), Département des Sciences alimentaires, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000, Algérie and 4Univ. Lille, INRA, ISA, Univ. Artois, Univ. Littoral Côte d'Opale, EA 7394-ICV- Institut Charles Viollette, F-59000Lille, France.

Background: The actinomycetes strains isolated from unexplored ecosystems are a promising alternative for the biosynthesis of novel antimicrobial compounds. Depending on the interesting antifungal activity of the studied strain S19, the statistical method seems to be an effective tool for optimizing the production of anticandidal molecules.

Introduction: This study was conducted in order to optimize the culture parameters (medium nutrients concentrations and initial pH value) affecting the production of antifungal metabolites from S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/2211352516666180813102424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596383PMC
April 2019
8 Reads

Novel Diazenyl Containing Phenyl Styryl Ketone Derivatives as Antimicrobial Agents.

Antiinfect Agents 2019 Apr;17(1):28-38

aSanthiram College of Pharmacy, Nandyal, Andhra Pradesh, India; bCreative Educational Society's College of Pharmacy, Kurnool, India; cBITS Pilani Hyderabad, Hyderabad, Telangana, India.

Background: Antibiotics play an important role in the treatment of infections to the hu-mans and at the same time, irrational, frequent prescription of higher antibiotics, change in gene com-position of microorganisms are all the reasons behind the development and introduction of new anti-biotics against different microorganisms.

Objective: In this project, an attempt has been made to synthesize some derivatives of diazenyl con-taining phenyl styryl ketones and also their in vitro screening was conducted against Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus, As-pergillus niger and Candida albicans.

Methods: Ten molecules were synthesized which are diazenyl containing chalcones. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/2211352516666180927111546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596389PMC
April 2019
1 Read

Extract Induces Cell Death of Mammalian Cells.

Antiinfect Agents 2018 ;16(2):144-146

I3S, Instituto de Investigação e Inovação da Universidade do Porto, Portugal.

Background: Fascioliasis is a neglected tropical disease that affects poor people from poor and developing countries. In the world, it has been estimated that at least 2.6 million people are affected with this disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1570180815666180531102555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075840PMC
January 2018
1 Read

Sulfonamides as Inhibitors of - Potential New Treatments for Leishmaniasis.

Antiinfect Agents 2017 Apr;15(1):57-62

Chemistry Department, Illinois State University, Normal, IL, USA.

Introduction: Leishmaniasis is an endemic disease caused by the protozoan parasite Leishmania. Current treatments for the parasite are limited by cost, availability and drug resistance as the occurrence of leishmaniasis continues to be more prevalent. Sulfonamides are a class of compounds with medicinal properties which have been used to treat bacterial and parasitic disease via various pathways especially as antimetabolites for folic acid. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/2211352515666170216143401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748876PMC
April 2017
1 Read

Better Antiretroviral Central Nervous System Penetration is Not Associated with Reduced Chronic Pain in People Living with Human Immunodeficiency Virus.

Antiinfect Agents 2016;14(1):38-46

Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Objective: To determine if better antiretroviral (ARV) central nervous system (CNS) penetration is associated with reduced rates of chronic pain in people living with HIV (PLWH).

Background: Chronic pain remains prevalent in PLWH despite widespread ARV use. Mechanisms underlying this prevalence remain unknown, though neuroinflammation from persistent CNS HIV infection and maladaptive plastic changes in the CNS have been implicated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/2211352514666151119211107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831626PMC
January 2016
2 Reads
  • Page 1 of 1