Microb Pathog 2023 Oct 14;183:106305. Epub 2023 Aug 14.
Pulmonary, Critical Care & Sleep Medicine, Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA; Pulmonary Section, Medicine Service, Veterans Affairs Medical Center, Oklahoma City, OK, 73104, USA. Electronic address:
Inhalation anthrax, the deadliest form of the disease, requires inhaled B. anthracis spores to escape from the alveolar space and travel to the mediastinal lymph nodes, from where the vegetative form of the pathogen disseminates, resulting in a rapidly fatal outcome. The role of epithelia in alveolar escape is unclear, but previous work suggests these epithelial cells are involved in this process. Read More