Search Our Scientific Publications & Authors

Eye (Lond) 2020 Jun 18. Epub 2020 Jun 18.

Núcleo de Telessaúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Objectives: This study evaluates the quality of ophthalmic images acquired by a nurse technician trained in teleophthalmology as compared with images acquired by an ophthalmologist, in order to provide a better understanding of the workforce necessary to operate remote care programs.

Methods: A cross-sectional study was performed on 2044 images obtained from 118 participants of the TeleOftalmo project, in Brazil. Fundus and slit-lamp photography were performed on site by an ophthalmologist and by a nurse technician under the supervision of a remote ophthalmologist. Read More

BMC Ophthalmol 2020 Jun 8;20(1):221. Epub 2020 Jun 8.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku, Tokyo, 101-8309, Japan.

Background: Immune checkpoint inhibitors have recently been widely used for advanced cancers and are known to cause ocular complications. We herein report a case developing bilateral serous retinal detachments, without ocular inflammation, after starting nivolumab treatment.

Case Presentation: A 73-year-old man was referred to our hospital, having become aware of metamorphopsia 2 months after starting nivolumab (anti-programmed cell death protein 1 monoclonal antibody) for malignant melanoma of the nasal cavity. Read More

Lung Cancer 2020 Jul 28;145:167-172. Epub 2020 Apr 28.

Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA, USA.

Objectives: During crizotinib clinical evaluation, visual disturbances, generally of grade 1 severity, were frequently reported adverse events (AE). Consequently, ophthalmologic assessments were included in a patient subgroup enrolled in PROFILE 1001 (NCT00585195), a phase 1, open-label, single-arm trial of crizotinib in patients with advanced non-small-cell lung cancer and are reported here.

Materials And Methods: At least 30 patients were required to undergo ophthalmologic assessments, including: best-corrected visual acuity (BCVA), refractive error, pupil size, slit-lamp anterior segment biomicroscopy, intraocular inflammation, intraocular pressure, retinal fundoscopic exams, fundus photography, ocular characteristics, and optical coherence tomography (OCT). Read More

Am J Ophthalmol Case Rep 2020 Jun 7;18:100691. Epub 2020 Apr 7.

Bascom Palmer Eye Institute And, University of Miami Miller School of Medicine 900 NW 17th Street, Miami, FL, 33136, USA.

Purpose: To report a case of bilateral uveitis secondary to intravenous nivolumab therapy in a patient with stage IV non-small cell lung cancer.

Observations: A 53-year-old male with stage IV non-small cell lung cancer presented with gradual onset of blurry vision in the left eye for nine days after completion of the first cycle of intravenous nivolumab chemotherapy. At initial presentation, best-corrected visual acuity was 20/25 in the right eye and 20/30 in the left eye. Read More

Case Rep Ophthalmol Med 2020 10;2020:8398054. Epub 2020 Mar 10.

Department of Ophtalmology, Antalya Education and Research Hospital, Antalya, Turkey.

Purpose: The purpose of this case report is to present the findings of optical coherence tomography angiography (OCTA) of a patient with bilateral choroidal neovascularization (CNV) associated with optic disc drusen (ODD), who was treated with intravitreal aflibercept injection. A 14-year-old girl presented with a complaint of visual loss and metamorphopsia in her both eyes. Best-corrected visual acuity (BCVA) was 20/32 and 20/25, respectively, in the right and left eyes. Read More

Am J Ophthalmol Case Rep 2020 Jun 15;18:100618. Epub 2020 Feb 15.

Francis I. Proctor Foundation, 95 Kirkham St, University of California, San Francisco, CA, 94143, USA.

Purpose: This is a retrospective case report illustrating the diagnostic and therapeutic challenges associated with a chronic rhegmatogenous retinal detachment masquerading as a severe panuveitis with intense anterior chamber inflammation. We have included clinical features, anterior segment and fundus photography, B-scan ultrasonography, fluorescein angiography, and intraoperative findings.

Observations: A 26-year-old male presented with features of unilateral panuveitis: hypotony, anterior segment inflammation (posterior synechiae and anterior chamber cell with fibrin clumping), diffuse choroidal thickening, and retinal detachment. Read More

Eye Vis (Lond) 2020 19;7. Epub 2020 Jan 19.

2School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuan Road, Wenzhou, 325027 Zhejiang China.

Background: China is undergoing a massive transition toward an urban and industrial economy. These changes will restructure the demographics and economy which will eventually influence the future patterns of disease. The risk factors of vision-impairing eye diseases remain ambiguous and poorly understood. Read More

Open Respir Med J 2019 31;13:19-30. Epub 2019 Jul 31.

Somnlogist, Sleep Research Unit, Department of Psychiatry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Purpose: This study sought to identify the magnitude and the possible risk factors of ocular complications in patients with Obstructive Sleep Apnea (OSA).

Methods: A hospital-based cross-sectional study with a nested case-control design was conducted. Qualifying study subjects were patients who had been diagnosed with moderate to severe OSA (AHI index of ≥ 5, n=80), and control subjects (n=20) who had an AHI index of ≤ 5 ("normal"). Read More

Curr Eye Res 2020 Jun 12;45(6):742-748. Epub 2019 Dec 12.

Department of Orthopedics, Jingzhou First People's Hospital, The First Affiliated Hospital of Yangtze University, Jingzhou, China.

: This study aims to evaluate the risk factors of retinal re-detachment and visual outcome after silicone oil removal (SOR) in silicone oil-filled eyes.: A total of 57 patients who underwent pars plana vitrectomy (PPV) and silicone oil injection for retinal detachment (RD), and subsequently underwent a silicone oil removal procedure. Pre-operative examinations were performed to determine the best-corrected visual acuity (BCVA) using the Snellen chart, while Icare was used to determine the intraocular pressure (IOP). Read More

World J Clin Cases 2019 Aug;7(16):2341-2345

Department of Ophthalmology, Tenth People's Hospital of Shanghai Affiliated to Tongji University, Shanghai 200072, China.

Background: Due to some similarities in the manifestations between central serous chorioretinopathy (CSC) and polypoidal choroidal vasculopathy (PCV), PCV may be misdiagnosed as CSC. More attention should be paid to distinguishing these two disorders.

Case Summary: A 52-year-old woman presented to our hospital with blurred vision in her left eye for approximately 1 wk. Read More

Int Ophthalmol 2019 Dec 15;39(12):2913-2922. Epub 2019 Jul 15.

Department of Ophthalmology, Faculty of Medicine, Erciyes University, 38039, Kayseri, Turkey.

Purpose: This prospective clinical case series aimed to investigate the safety and efficacy of suprachoroidal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in patients with optic nerve diseases.

Methods: This prospective, single-center, phase 1/2 study enrolled 4 eyes of 4 patients with optic atrophy of various reasons who underwent suprachoroidal implantation of ADMSCs. The best-corrected visual acuity (BCVA) in the study was HM at 1 m. Read More

Ophthalmic Genet 2019 06 2;40(3):288-292. Epub 2019 Jul 2.

a Department of Ophthalmology , University Hospital Virgen Macarena , Seville , Spain.

: To characterize the phenotype and genotype of a rare syndrome associating posterior microphthalmos (PM), retinitis pigmentosa (RP), and foveoschisis in a consanguineous Spanish family. : The study involved five family members, consisting of three siblings and their parents. All members underwent comprehensive eye examinations for best corrected visual acuity, axial length and refractive error, electroretinography (ERG), fundus photography, retinal fluorescein angiography (FA), and optical coherence tomography (OCT). Read More

Cell Reprogram 2018 12;20(6):329-336

5 Department of Ophthalmology, Faculty of Medicine, Erciyes University , Kayseri, Turkey .

This prospective clinical case series aimed to investigate the safety and efficacy of suprachoroidal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in patients with dry-type age-related macular degeneration (AMD) and Stargardt's macular dystrophy (SMD). This study included four patients with advanced-stage dry-type AMD and four patients with SMD who underwent suprachoroidal implantation of ADMSCs. The best-corrected visual acuity (BCVA) in the study was 20/200. Read More

Ophthalmol Retina 2019 06 6;3(6):516-522. Epub 2019 Feb 6.

Department of Vitreoretina, M. M. Joshi Eye Institute, Hubballi, Karnataka, India.

Purpose: To report a novel finding of epiretinal neovascularization (ERN) in cases of macular telangiectasia (MacTel) type 2 and describe its clinical and multimodal imaging features.

Design: Retrospective chart review.

Participants: Patients attending the retina clinic from January 2017 through April 2018. Read More

BMC Ophthalmol 2019 May 30;19(1):122. Epub 2019 May 30.

Eye Institute, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, 200031, China.

Background: Anterior megalophthalmos is a rare congenital disease which mainly features enlargement of the anterior segment. Cataract surgeries in anterior megalophthalmos can be challenging due to the anatomical anomalies while the studies upon the surgical design have been less integrated.

Case Presentation: A 37-year-old woman presented with progressively blurred vision in the right eye after a transient fever 10 months ago. Read More

J Fr Ophtalmol 2019 Sep 25;42(7):722-729. Epub 2019 May 25.

Service d'ophtalmologie, hôpital Necker, Hôpital Necker 75015 Paris, France; Hôpital Necker, Ophtara, centre de référence des maladies rares en ophtalmologie, Hôpital Necker 75015 Paris; Université Paris-Descartes.

Introduction: The goal of this study was to describe and analyze the ophthalmological manifestations found in 21 patients followed for Ehlers-Danlos Syndrome in our department.

Methods: This retrospective study analyzed 21 consecutive patients (17 women and 4 men) with Ehlers-Danlos syndrome seen in the Necker hospital, Paris, between April 2016 and November 2017. The mean age was 25. Read More

J Ocul Pharmacol Ther 2019 06 15;35(5):283-290. Epub 2019 May 15.

1 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

To evaluate the efficacy and primary safety of treatment with artesunate in reducing ocular neovascularization in humans. Five patients with corneal, iris, and retinal neovascularization and no light perception were treated with intravitreal injections of artesunate 80 μg. Visual acuity, anterior segment photography, fundus fluorescein angiography, and optical coherence tomography were used to evaluate efficacy, while intraocular pressure (IOP) and lens opacity degree were employed to evaluate safety. Read More

J Ocul Pharmacol Ther 2019 05 9;35(4):245-253. Epub 2019 Apr 9.

1 Genentech, Inc., Department of Safety Assessment, South San Francisco, California.

To characterize the inflammatory response and determine the no-observable-effect level (NOEL) in cynomolgus monkey eyes after intravitreal (ITV) injection of endotoxin. The inflammatory response to endotoxin was assessed in a single-dose study in monkeys at doses of 0.01 to 0. Read More

Ophthalmic Epidemiol 2019 06 29;26(3):150-154. Epub 2018 Nov 29.

d School of Optometry and Vision Science , UNSW , Sydney , Australia.

Purpose: To report the prevalence of primary glaucoma as identified by study optometrists of the L. V. Prasad Eye Institute - Glaucoma Epidemiology and Molecular Genetics Study (LVPEI-GLEAMS). Read More

Can J Ophthalmol 2018 10 1;53(5):471-473. Epub 2018 Feb 1.

Department of Ophthalmology, University of Alberta, Edmonton, Alta.; Department of Surgery, University of Calgary, Calgary, Alta.. Electronic address:

Objective: To investigate the validity and safety of tele-ophthalmology evaluations as a clinical assessment tool when performed by an ophthalmologist to detect lesion growth in patients with low-, medium-, and high-risk choroidal and iris nevi.

Design: Retrospective observational pilot study.

Methods: Consecutive patients with low-/medium-/high-risk choroidal or iris nevi who underwent tele-oncology examinations over 5 months. Read More

Zhonghua Yan Ke Za Zhi 2018 Sep;54(9):652-660

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing 100005, China.

To study the histopathology manifestation and imaging characteristics of confocal microscopy (IVCM) for diagnosis of ocular surface squamous neoplasia (OSSN) and analyze the reliability of IVCM in differential diagnosis from OSSN cases. A prospective study. Twenty-three patients (23 eyes) with OSSN were collected from September 2015 to November 2017 in Beijing Tongren Eye center. Read More

BMC Ophthalmol 2018 Sep 12;18(1):245. Epub 2018 Sep 12.

Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China.

Background: Our study aimed to investigate the ocular surface health of Shanghai University students.

Methods: This is a cross-sectional study carried out among freshmen and sophomores on the main campus of Shanghai University. Questionnaires including the widely-used ocular surface disease index (OSDI) and the Zung Self-rating Anxiety Scale (SAS) were completed first, and then ocular examinations were conducted regarding height & weight, blood pressure and heart rate, optometry, intraocular pressure exam, vision and subjective refraction, Aladdin, Macular pigment density measurement, tear test, anterior segment examination, fundus photography, ophthalmologist check, TOPCON OCT check, and Collin's fundus blood test. Read More

Indian J Ophthalmol 2018 08;66(8):1109-1112

Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: This study aimed to report the clinical profile of patients with posterior scleritis at a tertiary eye center in Eastern India.

Methods: This was a single-center retrospective case series of patients who were diagnosed as posterior scleritis between January 2010 and December 2014, with a follow-up period of at least 6 months.

Results: The study included 18 patients of posterior scleritis with a mean age of 41. Read More

Diagn Interv Radiol 2018 May-Jun;24(3):135-138

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Cesarean section is the most commonly performed surgical procedure in women. The surgical incision line in the uterus is generally located in the lower segment of the anterior uterine wall. Acquaintance with the normal and abnormal findings of the anterior uterine wall is of critical importance for imagers in this era of ever increasing cesarean sections performed worldwide. Read More

Acta Ophthalmol 2018 Dec 19;96(8):e974-e978. Epub 2018 Apr 19.

Department of Ophthalmology, University Medical Center, Johannes Gutenberg-University, Mainz, Germany.

Purpose: The major goal of this study was to test the hypothesis that in patients with peripheral hypertrophic subepithelial corneal opacification (PHSCO), visualization of corneal vessels is better with optical coherence tomography angiography (OCTA) than with conventional slit lamp microphotography.

Methods: Patients with PHSCO were included in this prospective study. The corneal findings were photographed using a slit lamp camera (Haag Streit BM 900 ) and visualized with anterior-segment OCT (Optovue XR Avanti, Fremont, California, USA). Read More

Ophthalmic Epidemiol 2018 08 26;25(4):306-314. Epub 2018 Mar 26.

c See Acknowledgements for members of the African American Eye Disease Study Group.

Purpose: To describe the study design, operational and recruitment strategies, procedures, and baseline characteristics of the African American Eye Disease Study (AFEDS), a population-based assement of the prevalence of visual impairment, ocular disease, visual function, and health-related quality of life in African Americans.

Methods: This population-based, cross-sectional study included over 6000 African Americans 40 years and older residing in and around Inglewood, California. A detailed interview and eye examination was performed on each eligible participant. Read More

Turk J Ophthalmol 2018 Feb 23;48(1):52-55. Epub 2018 Feb 23.

Ulucanlar Eye Training and Research Hospital, Ophthalmology Clinic, Ankara, Turkey.

In this report, we describe three cases of retinal macrovessel. Two of the three patients presented to our clinic for annual eye exam and had no visual complaints. The third patient presented because of vision loss in the left eye. Read More

Acta Ophthalmol 2018 Jun 25;96(4):356-363. Epub 2018 Mar 25.

University Eye Clinic, Maastricht University Medical Centre, Maastricht, the Netherlands.

Purpose: To evaluate the relationship between subjective and objective measurements of lens density and the energy of phacoemulsification.

Setting: University Eye Clinic, Maastricht University Medical Centre, Maastricht, the Netherlands.

Design: Cross-sectional study. Read More

J AAPOS 2018 04 16;22(2):145.e1-145.e6. Epub 2018 Mar 16.

International Centre for Advancement of Rural Eye Care, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To estimate the prevalence and causes of visual impairment and other ocular comorbidities among tribal children in an urban school population in eastern India.

Method: In this cross-sectional study, vision screening tests were administered to tribal school children. Demographic data, including name, age, sex, home district, height, and weight of each child, and examination data, including unaided and pinhole visual acuity, external eye examination with a flashlight, slit-lamp examination, intraocular pressure (IOP) measurement, and undilated fundus photography, were collected. Read More

Retin Cases Brief Rep 2018 Feb 22. Epub 2018 Feb 22.

Department of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, India.

Purpose: To describe multicolor imaging findings in a case of acute retinal pigment epitheliitis.

Setting: Vitreoretinal department of a tertiary care center in Eastern India.

Methods: A 28-year-old lady presented with acute vision loss in the right eye since 3 days. Read More

Vet Ophthalmol 2019 Jan 20;22(1):13-23. Epub 2018 Feb 20.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.

Objective: To estimate the prevalence of ocular disease and obtain normative ocular data for free-living hummingbirds.

Animals Studied: Two hundred and sixty-three free-living, adult Hummingbirds from coastal and inland central California were studied, including Anna's (Calypte anna, n = 186) and Black-chinned (Archilochus alexandri; n = 77) hummingbirds.

Procedures: Slit lamp biomicroscopy and indirect ophthalmoscopy were performed on all individuals. Read More

Am J Transl Res 2018 15;10(1):235-245. Epub 2018 Jan 15.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen UniversityGuangzhou 510060, Guangdong, China.

Purpose: To assess the appropriate dose of sodium nitroprusside for establishing acute retinal photoreceptor degeneration models in rabbits.

Methods: Sodium nitroprusside (SNP) was delivered intravitreously. Sixteen New Zealand White rabbits are divided into four groups randomly: 0. Read More

Am J Ophthalmol Case Rep 2017 Sep 22;7:99-101. Epub 2017 Jun 22.

Department of Ophthalmology, California Pacific Medical Center, 711 Van Ness, Suite 250, San Francisco, CA, 94102, USA.

Purpose: To report the association of rubeosis iridis with chronic bullous degenerative peripheral retinoschisis.

Observations: A 63-year-old female presented with acute hyphema and neovascularization of the iris in association with elevated intraocular pressure. Posterior segment examination including imaging revealed no vascular occlusion as a potential cause. Read More

Ophthalmic Genet 2018 04 4;39(2):271-274. Epub 2017 Dec 4.

a Department of Ophthalmology and Visual Sciences , University of Illinois at Chicago, Illinois Eye and Ear Infirmary , Chicago , IL, USA.

Background: Wolf-Hirschhorn syndrome is a rare genetic syndrome caused by a heterozygous deletion on chromosome 4p16.3 and is characterized by a "Greek warrior helmet" facies, hypotonia, developmental delay, seizures, structural central nervous system defects, intrauterine growth restriction, sketelal anomalies, cardiac defects, abnormal tooth development, and hearing loss. A variety of ocular manifestations may occur in up to 40% of patients. Read More

Zhonghua Yan Ke Za Zhi 2017 Oct;53(10):740-745

Peking University People's Hospital, Ophthalmology Department, Key Laboratory of Vision Loss and Restoration Ministry of Education, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.

To explore clinical and laboratory factors that influencing treating procedure of cytomegalovirus retinitis (CMVR) after allogeneic bone marrow hematopoietic stem cell transplantation (HSCT). This is a retrospective case series study. A total of 9 CMVR patients (15 eyes) between January 2016 and March 2017 were included in this study. Read More

Clin Ophthalmol 2017 14;11:1301-1307. Epub 2017 Jul 14.

Department of Ophthalmology, The Byers Eye Institute, Stanford University School of Medicine.

Objective: We aimed at evaluating the ability of individuals without ophthalmologic training to quickly capture high-quality images of the cornea by using a smartphone and low-cost anterior segment imaging adapter (the "EyeGo" prototype).

Methods: Seven volunteers photographed 1,502 anterior segments from 751 high school students in Varni, India, by using an iPhone 5S with an attached EyeGo adapter. Primary outcome measures were median photograph quality of the cornea and anterior segment of the eye (validated Fundus Photography vs Ophthalmoscopy Trial Outcomes in the Emergency Department [FOTO-ED] study; 1-5 scale; 5, best) and the time required to take each photograph. Read More

Photodiagnosis Photodyn Ther 2017 Sep 18;19:383-387. Epub 2017 Jul 18.

Department of Ophthalmology, the First Affiliated Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, PR China; Diabetic Eye Center of Liaoning Province, No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, PR China. Electronic address:

We report a case of idiopathic paracentral acute middle maculopathy with typical optical imaging and clinical features. A 26-year-old Chinese policeman presented with a 20-day history of paracentral scotoma in the left eye after early wake-up and long-time working in front of computer the day before. He experienced sudden-onset strong flash in his left eye. Read More

Zhonghua Yan Ke Za Zhi 2017 Jul;53(7):509-513

Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

To determine the prevalence of diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN) in the Beijing Desheng Diabetic Eye Disease Study cohort and to investigate the association between DR and DPN. Cross-sectional study in a type 2 diabetic cohort. Questionnaires were collected and physical examinations were performed. Read More

Indian J Ophthalmol 2017 Jul;65(7):610-612

Department of Ophthalmology, JNMC, Belagavi, Karnataka, India.

The incidence of the craniofacial cleft is rare ranging between 1.43 and 4.85/100,000 births. Read More

Mol Med Rep 2017 Aug 20;16(2):1753-1758. Epub 2017 Jun 20.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑sen University, Guangzhou, Guangdong 510060, P.R. China.

The purpose of the current study was to identify novel mutations in the FRMD7 (FERM domain containing 7) gene and to characterize clinical features in Chinese patients with congenital motor nystagmus. For this purpose, 18 patients with congenital motor nystagmus were selected from the ocular genetic diseases bank of the Pediatric and Genetic Clinic of Zhongshan Ophthalmic Center (Guangdong, China). Direct sequencing was used to analyze the exons and adjacent introns of the FRMD7 gene. Read More

Ophthalmol Ther 2017 Jun 5;6(1):93-104. Epub 2017 May 5.

Department of Ophthalmology, University Hospitals Leuven, Louvain, Belgium.

Cystinosis is a rare autosomal recessive disease with an incidence of approximately 1 case per 100,000-200,000 live births. Over the years, gaining in-depth knowledge of the disease has led to vast improvement in patient life expectancy. However, debilitating, extra-renal manifestations such as eye disease, in particular corneal crystal deposition and its associated photophobia, still occur frequently, regardless of patient age and notwithstanding the increased implementation of systemic therapy. Read More

PLoS One 2017 4;12(4):e0174867. Epub 2017 Apr 4.

Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.

Purpose: To present the rates of referral of participants in the National Eye Health Survey (NEHS) for further eye care.

Materials & Methods: A national sample of 3098 non-Indigenous Australians aged 50-98 and 1738 Indigenous Australians aged 40-92 years living in 30 randomly selected sites was recruited using a door-to-door approach. Participants completed a general questionnaire and a series of eye tests, including vision and anterior segment assessment, intra-ocular pressure measurement, visual field testing and fundus photography. Read More

Ophthalmic Epidemiol 2017 12 27;24(6):353-363. Epub 2017 Mar 27.

a Centre for Eye Research Australia , Royal Victorian Eye and Ear Hospital , Melbourne , Australia.

Purpose: To present the recruitment and testing methodology of the National Eye Health Survey (NEHS), a population-based study that aimed to determine the prevalence and causes of vision impairment and blindness in Australia.

Methods: Non-Indigenous Australians aged 50 years and older and Indigenous Australians aged 40 years and older were recruited using a door-to-door approach from 30 randomly selected geographical areas, stratified by remoteness. Participants underwent a vision examination, anterior segment assessment, intraocular pressure testing, perimetry, and fundus photography. Read More

Mol Med Rep 2017 May 23;15(5):3069-3075. Epub 2017 Mar 23.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑sen University, Guangzhou, Guangdong 510060, P.R. China.

The aim of the present study was to evaluate mutations of the G protein-coupled receptor 143 (GPR143) gene for ocular albinism type 1 (OA1) in Chinese patients. For the current study, 8 patients with OA1 were selected from the database of ocular genetic diseases. Genomic DNA of OA1 was prepared from venous leukocytes collected from the patients. Read More

Retin Cases Brief Rep 2019 Summer;13(3):260-265

Ophthalmology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Purpose: The aim of this study is to describe the clinical presentation of vortex vein varices with multimodal imaging.

Methods: The authors carried out a retrospective case series of eight patients (7 female, 1 male) with an average age of 60.2 years (min 8, max 84, median 68. Read More

Ocul Oncol Pathol 2017 Jan 1;3(1):49-55. Epub 2016 Oct 1.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa., USA.

Background/aims: To evaluate the technical feasibility of a consumer-grade cellular iPhone camera as an ocular imaging device compared to existing ophthalmic imaging equipment for documentation purposes.

Methods: A comparison of iPhone 4s and 5s images was made with external facial images (macrophotography) using Nikon cameras, slit-lamp images (microphotography) using Zeiss photo slit-lamp camera, and fundus images (fundus photography) using RetCam II.

Results: In an analysis of six consecutive patients with ophthalmic conditions, both iPhones achieved documentation of external findings (macrophotography) using standard camera modality, tap to focus, and built-in flash. Read More

Retin Cases Brief Rep 2018 Fall;12(4):367-370

Department of Ophthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.

Purpose: To describe a case of macular microcysts associated with advanced secondary glaucoma from Schwartz-Matsuo syndrome.

Methods: Clinical presentation, color fundus photography, optic disk photography, visual fields, and optical coherence tomography are presented.

Results: A 32-year-old woman presented with advanced, unilateral secondary glaucoma associated with a macula-on rhegmatogenous retinal detachment. Read More

Stem Cell Res Ther 2016 12 1;7(1):178. Epub 2016 Dec 1.

Genome and Stem Cell Center (GENKOK), Erciyes University, Kayseri, Turkey.

Background: This prospective clinical case series aimed to investigate the safety of subretinal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in advanced stage retinitis pigmentosa (RP).

Methods: This study included 11 patients with end-stage RP who received subretinal implantation of ADMSCs. All patients had a total visual field defect and five of them only had light perception. Read More

Br J Ophthalmol 2017 07 25;101(7):856-861. Epub 2016 Nov 25.

University Claude Bernard-Lyon 1, Villeurbanne, France.

Aims: To determine the long-term visual and systemic outcomes of uveitis patients with biopsy-proven sarcoidosis.

Methods: A retrospective study of biopsy-proven sarcoid uveitis, with a 3-year minimum follow-up, seen at Lyon University Hospital, between April 2004 and January 2016.

Results: A total of 83 patients were included, with a median age at onset of 52 (37-62) years and an unbalanced gender ratio (women 77. Read More

Indian J Ophthalmol 2016 Sep;64(9):663-667

Department of Vitreoretinal Diseases, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.

This article describes the method to make a do it yourself smartphone-based fundus camera which can image the central retina as well as the peripheral retina up to the pars plana. It is a cost-effective alternative to the fundus camera. Read More