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Ophthalmic Epidemiol 2018 Nov 29:1-5. Epub 2018 Nov 29.

d School of Optometry and Vision Science , UNSW , Sydney , Australia.

Purpose: To report the prevalence of primary glaucoma as identified by study optometrists of the L. V. Prasad Eye Institute - Glaucoma Epidemiology and Molecular Genetics Study (LVPEI-GLEAMS). Read More

Can J Ophthalmol 2018 Oct 1;53(5):471-473. Epub 2018 Feb 1.

Department of Ophthalmology, University of Alberta, Edmonton, Alta.; Department of Surgery, University of Calgary, Calgary, Alta.. Electronic address:

Objective: To investigate the validity and safety of tele-ophthalmology evaluations as a clinical assessment tool when performed by an ophthalmologist to detect lesion growth in patients with low-, medium-, and high-risk choroidal and iris nevi.

Design: Retrospective observational pilot study.

Methods: Consecutive patients with low-/medium-/high-risk choroidal or iris nevi who underwent tele-oncology examinations over 5 months. Read More

Zhonghua Yan Ke Za Zhi 2018 Sep;54(9):652-660

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing 100005, China.

To study the histopathology manifestation and imaging characteristics of confocal microscopy (IVCM) for diagnosis of ocular surface squamous neoplasia (OSSN) and analyze the reliability of IVCM in differential diagnosis from OSSN cases. A prospective study. Twenty-three patients (23 eyes) with OSSN were collected from September 2015 to November 2017 in Beijing Tongren Eye center. Read More

BMC Ophthalmol 2018 Sep 12;18(1):245. Epub 2018 Sep 12.

Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China.

Background: Our study aimed to investigate the ocular surface health of Shanghai University students.

Methods: This is a cross-sectional study carried out among freshmen and sophomores on the main campus of Shanghai University. Questionnaires including the widely-used ocular surface disease index (OSDI) and the Zung Self-rating Anxiety Scale (SAS) were completed first, and then ocular examinations were conducted regarding height & weight, blood pressure and heart rate, optometry, intraocular pressure exam, vision and subjective refraction, Aladdin, Macular pigment density measurement, tear test, anterior segment examination, fundus photography, ophthalmologist check, TOPCON OCT check, and Collin's fundus blood test. Read More

Indian J Ophthalmol 2018 08;66(8):1109-1112

Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: This study aimed to report the clinical profile of patients with posterior scleritis at a tertiary eye center in Eastern India.

Methods: This was a single-center retrospective case series of patients who were diagnosed as posterior scleritis between January 2010 and December 2014, with a follow-up period of at least 6 months.

Results: The study included 18 patients of posterior scleritis with a mean age of 41. Read More

Diagn Interv Radiol 2018 May-Jun;24(3):135-138

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Cesarean section is the most commonly performed surgical procedure in women. The surgical incision line in the uterus is generally located in the lower segment of the anterior uterine wall. Acquaintance with the normal and abnormal findings of the anterior uterine wall is of critical importance for imagers in this era of ever increasing cesarean sections performed worldwide. Read More

Acta Ophthalmol 2018 Dec 19;96(8):e974-e978. Epub 2018 Apr 19.

Department of Ophthalmology, University Medical Center, Johannes Gutenberg-University, Mainz, Germany.

Purpose: The major goal of this study was to test the hypothesis that in patients with peripheral hypertrophic subepithelial corneal opacification (PHSCO), visualization of corneal vessels is better with optical coherence tomography angiography (OCTA) than with conventional slit lamp microphotography.

Methods: Patients with PHSCO were included in this prospective study. The corneal findings were photographed using a slit lamp camera (Haag Streit BM 900 ) and visualized with anterior-segment OCT (Optovue XR Avanti, Fremont, California, USA). Read More

Ophthalmic Epidemiol 2018 Aug 26;25(4):306-314. Epub 2018 Mar 26.

c See Acknowledgements for members of the African American Eye Disease Study Group.

Purpose: To describe the study design, operational and recruitment strategies, procedures, and baseline characteristics of the African American Eye Disease Study (AFEDS), a population-based assement of the prevalence of visual impairment, ocular disease, visual function, and health-related quality of life in African Americans.

Methods: This population-based, cross-sectional study included over 6000 African Americans 40 years and older residing in and around Inglewood, California. A detailed interview and eye examination was performed on each eligible participant. Read More

Turk J Ophthalmol 2018 Feb 23;48(1):52-55. Epub 2018 Feb 23.

Ulucanlar Eye Training and Research Hospital, Ophthalmology Clinic, Ankara, Turkey.

In this report, we describe three cases of retinal macrovessel. Two of the three patients presented to our clinic for annual eye exam and had no visual complaints. The third patient presented because of vision loss in the left eye. Read More

Acta Ophthalmol 2018 Jun 25;96(4):356-363. Epub 2018 Mar 25.

University Eye Clinic, Maastricht University Medical Centre, Maastricht, the Netherlands.

Purpose: To evaluate the relationship between subjective and objective measurements of lens density and the energy of phacoemulsification.

Setting: University Eye Clinic, Maastricht University Medical Centre, Maastricht, the Netherlands.

Design: Cross-sectional study. Read More

J AAPOS 2018 Apr 16;22(2):145.e1-145.e6. Epub 2018 Mar 16.

International Centre for Advancement of Rural Eye Care, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

Purpose: To estimate the prevalence and causes of visual impairment and other ocular comorbidities among tribal children in an urban school population in eastern India.

Method: In this cross-sectional study, vision screening tests were administered to tribal school children. Demographic data, including name, age, sex, home district, height, and weight of each child, and examination data, including unaided and pinhole visual acuity, external eye examination with a flashlight, slit-lamp examination, intraocular pressure (IOP) measurement, and undilated fundus photography, were collected. Read More

Retin Cases Brief Rep 2018 Feb 22. Epub 2018 Feb 22.

Department of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, India.

Purpose: To describe multicolor imaging findings in a case of acute retinal pigment epitheliitis.

Setting: Vitreoretinal department of a tertiary care center in Eastern India.

Methods: A 28-year-old lady presented with acute vision loss in the right eye since 3 days. Read More

Vet Ophthalmol 2018 Feb 20. Epub 2018 Feb 20.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.

Objective: To estimate the prevalence of ocular disease and obtain normative ocular data for free-living hummingbirds.

Animals Studied: Two hundred and sixty-three free-living, adult Hummingbirds from coastal and inland central California were studied, including Anna's (Calypte anna, n = 186) and Black-chinned (Archilochus alexandri; n = 77) hummingbirds.

Procedures: Slit lamp biomicroscopy and indirect ophthalmoscopy were performed on all individuals. Read More

Am J Transl Res 2018 15;10(1):235-245. Epub 2018 Jan 15.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen UniversityGuangzhou 510060, Guangdong, China.

Purpose: To assess the appropriate dose of sodium nitroprusside for establishing acute retinal photoreceptor degeneration models in rabbits.

Methods: Sodium nitroprusside (SNP) was delivered intravitreously. Sixteen New Zealand White rabbits are divided into four groups randomly: 0. Read More

Am J Ophthalmol Case Rep 2017 Sep 22;7:99-101. Epub 2017 Jun 22.

Department of Ophthalmology, California Pacific Medical Center, 711 Van Ness, Suite 250, San Francisco, CA, 94102, USA.

Purpose: To report the association of rubeosis iridis with chronic bullous degenerative peripheral retinoschisis.

Observations: A 63-year-old female presented with acute hyphema and neovascularization of the iris in association with elevated intraocular pressure. Posterior segment examination including imaging revealed no vascular occlusion as a potential cause. Read More

Zhonghua Yan Ke Za Zhi 2017 Oct;53(10):740-745

Peking University People's Hospital, Ophthalmology Department, Key Laboratory of Vision Loss and Restoration Ministry of Education, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.

To explore clinical and laboratory factors that influencing treating procedure of cytomegalovirus retinitis (CMVR) after allogeneic bone marrow hematopoietic stem cell transplantation (HSCT). This is a retrospective case series study. A total of 9 CMVR patients (15 eyes) between January 2016 and March 2017 were included in this study. Read More

Clin Ophthalmol 2017 14;11:1301-1307. Epub 2017 Jul 14.

Department of Ophthalmology, The Byers Eye Institute, Stanford University School of Medicine.

Objective: We aimed at evaluating the ability of individuals without ophthalmologic training to quickly capture high-quality images of the cornea by using a smartphone and low-cost anterior segment imaging adapter (the "EyeGo" prototype).

Methods: Seven volunteers photographed 1,502 anterior segments from 751 high school students in Varni, India, by using an iPhone 5S with an attached EyeGo adapter. Primary outcome measures were median photograph quality of the cornea and anterior segment of the eye (validated Fundus Photography vs Ophthalmoscopy Trial Outcomes in the Emergency Department [FOTO-ED] study; 1-5 scale; 5, best) and the time required to take each photograph. Read More

Photodiagnosis Photodyn Ther 2017 Sep 18;19:383-387. Epub 2017 Jul 18.

Department of Ophthalmology, the First Affiliated Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, PR China; Diabetic Eye Center of Liaoning Province, No. 155 Nanjing Bei Street, Heping District, Shenyang City, Liaoning Province, 110001, PR China. Electronic address:

We report a case of idiopathic paracentral acute middle maculopathy with typical optical imaging and clinical features. A 26-year-old Chinese policeman presented with a 20-day history of paracentral scotoma in the left eye after early wake-up and long-time working in front of computer the day before. He experienced sudden-onset strong flash in his left eye. Read More

Zhonghua Yan Ke Za Zhi 2017 Jul;53(7):509-513

Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

To determine the prevalence of diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN) in the Beijing Desheng Diabetic Eye Disease Study cohort and to investigate the association between DR and DPN. Cross-sectional study in a type 2 diabetic cohort. Questionnaires were collected and physical examinations were performed. Read More

Indian J Ophthalmol 2017 Jul;65(7):610-612

Department of Ophthalmology, JNMC, Belagavi, Karnataka, India.

The incidence of the craniofacial cleft is rare ranging between 1.43 and 4.85/100,000 births. Read More

Mol Med Rep 2017 Aug 20;16(2):1753-1758. Epub 2017 Jun 20.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑sen University, Guangzhou, Guangdong 510060, P.R. China.

The purpose of the current study was to identify novel mutations in the FRMD7 (FERM domain containing 7) gene and to characterize clinical features in Chinese patients with congenital motor nystagmus. For this purpose, 18 patients with congenital motor nystagmus were selected from the ocular genetic diseases bank of the Pediatric and Genetic Clinic of Zhongshan Ophthalmic Center (Guangdong, China). Direct sequencing was used to analyze the exons and adjacent introns of the FRMD7 gene. Read More

Ophthalmol Ther 2017 Jun 5;6(1):93-104. Epub 2017 May 5.

Department of Ophthalmology, University Hospitals Leuven, Louvain, Belgium.

Cystinosis is a rare autosomal recessive disease with an incidence of approximately 1 case per 100,000-200,000 live births. Over the years, gaining in-depth knowledge of the disease has led to vast improvement in patient life expectancy. However, debilitating, extra-renal manifestations such as eye disease, in particular corneal crystal deposition and its associated photophobia, still occur frequently, regardless of patient age and notwithstanding the increased implementation of systemic therapy. Read More

PLoS One 2017 4;12(4):e0174867. Epub 2017 Apr 4.

Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.

Purpose: To present the rates of referral of participants in the National Eye Health Survey (NEHS) for further eye care.

Materials & Methods: A national sample of 3098 non-Indigenous Australians aged 50-98 and 1738 Indigenous Australians aged 40-92 years living in 30 randomly selected sites was recruited using a door-to-door approach. Participants completed a general questionnaire and a series of eye tests, including vision and anterior segment assessment, intra-ocular pressure measurement, visual field testing and fundus photography. Read More

Ophthalmic Epidemiol 2017 12 27;24(6):353-363. Epub 2017 Mar 27.

a Centre for Eye Research Australia , Royal Victorian Eye and Ear Hospital , Melbourne , Australia.

Purpose: To present the recruitment and testing methodology of the National Eye Health Survey (NEHS), a population-based study that aimed to determine the prevalence and causes of vision impairment and blindness in Australia.

Methods: Non-Indigenous Australians aged 50 years and older and Indigenous Australians aged 40 years and older were recruited using a door-to-door approach from 30 randomly selected geographical areas, stratified by remoteness. Participants underwent a vision examination, anterior segment assessment, intraocular pressure testing, perimetry, and fundus photography. Read More

Mol Med Rep 2017 May 23;15(5):3069-3075. Epub 2017 Mar 23.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑sen University, Guangzhou, Guangdong 510060, P.R. China.

The aim of the present study was to evaluate mutations of the G protein-coupled receptor 143 (GPR143) gene for ocular albinism type 1 (OA1) in Chinese patients. For the current study, 8 patients with OA1 were selected from the database of ocular genetic diseases. Genomic DNA of OA1 was prepared from venous leukocytes collected from the patients. Read More

Retin Cases Brief Rep 2017 Mar 22. Epub 2017 Mar 22.

*Ophthalmology Unit, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; †Ophthalmology Unit, Sacco Hospital, University of Milan, Milan, Italy; ‡University of Bologna, Bologna, Italy; and §Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Purpose: The aim of this study is to describe the clinical presentation of vortex vein varices with multimodal imaging.

Methods: The authors carried out a retrospective case series of eight patients (7 female, 1 male) with an average age of 60.2 years (min 8, max 84, median 68. Read More

Ocul Oncol Pathol 2017 Jan 1;3(1):49-55. Epub 2016 Oct 1.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa., USA.

Background/aims: To evaluate the technical feasibility of a consumer-grade cellular iPhone camera as an ocular imaging device compared to existing ophthalmic imaging equipment for documentation purposes.

Methods: A comparison of iPhone 4s and 5s images was made with external facial images (macrophotography) using Nikon cameras, slit-lamp images (microphotography) using Zeiss photo slit-lamp camera, and fundus images (fundus photography) using RetCam II.

Results: In an analysis of six consecutive patients with ophthalmic conditions, both iPhones achieved documentation of external findings (macrophotography) using standard camera modality, tap to focus, and built-in flash. Read More

Retin Cases Brief Rep 2018 Fall;12(4):367-370

Department of Ophthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, California.

Purpose: To describe a case of macular microcysts associated with advanced secondary glaucoma from Schwartz-Matsuo syndrome.

Methods: Clinical presentation, color fundus photography, optic disk photography, visual fields, and optical coherence tomography are presented.

Results: A 32-year-old woman presented with advanced, unilateral secondary glaucoma associated with a macula-on rhegmatogenous retinal detachment. Read More

Stem Cell Res Ther 2016 12 1;7(1):178. Epub 2016 Dec 1.

Genome and Stem Cell Center (GENKOK), Erciyes University, Kayseri, Turkey.

Background: This prospective clinical case series aimed to investigate the safety of subretinal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in advanced stage retinitis pigmentosa (RP).

Methods: This study included 11 patients with end-stage RP who received subretinal implantation of ADMSCs. All patients had a total visual field defect and five of them only had light perception. Read More

Br J Ophthalmol 2017 07 25;101(7):856-861. Epub 2016 Nov 25.

University Claude Bernard-Lyon 1, Villeurbanne, France.

Aims: To determine the long-term visual and systemic outcomes of uveitis patients with biopsy-proven sarcoidosis.

Methods: A retrospective study of biopsy-proven sarcoid uveitis, with a 3-year minimum follow-up, seen at Lyon University Hospital, between April 2004 and January 2016.

Results: A total of 83 patients were included, with a median age at onset of 52 (37-62) years and an unbalanced gender ratio (women 77. Read More

Indian J Ophthalmol 2016 Sep;64(9):663-667

Department of Vitreoretinal Diseases, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.

This article describes the method to make a do it yourself smartphone-based fundus camera which can image the central retina as well as the peripheral retina up to the pars plana. It is a cost-effective alternative to the fundus camera. Read More

Zhonghua Yan Ke Za Zhi 2016 Oct;52(10):745-748

Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Department of Ophthalmology, People's Hospital, Peking University, Beijing 100044, China.

To evaluate the efficacy of large spot indirect ophthalmoscopy laser alone or combined with systemic chemotherapy in the treatment of early and middle stage retinoblastoma. Retrospective series case study. Clinical data of 21 patients (22 eyes) who were diagnosed as retinoblastoma (RB) in Peking University People's Hospital from March 2009 to August 2014 were collected. Read More

Cesk Slov Oftalmol Fall 2016;72(3):86-90

Documentation of the anterior segment and the eye fundus with instruments that enable quality precision diagnostics is a common and important part of screening in humanitarian ophthalmology projects. It is the essential element in diagnosis, monitoring and management of eye diseases. In sub saharan countries within the screening for ophthalmologist are not available the modern technologies such as biomicroscope (slit lamp) or fundus camera. Read More

Invest Ophthalmol Vis Sci 2016 Sep;57(11):5023-5030

Department of Ophthalmology & Visual Sciences, University of Michigan, Ann Arbor, Michigan, United States 2Department of Cell & Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States.

Purpose: The purpose of this analysis was to assess the utility of Pitx2+/- mice as a model for the ocular features of Axenfeld-Rieger Syndrome and for congenital glaucoma.

Methods: Eyes of Pitx2+/- and wild-type littermates were examined clinically using optical coherence tomography (OCT) and fundus photography. Intraocular pressures were measured using a TonoLab rebound tonometer. Read More

Retin Cases Brief Rep 2018 Winter;12(1):12-16

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Purpose: To report subclinical retinal hemangioblastoma detected by enhanced depth imaging optical coherence tomography and fluorescein angiography in at-risk twins.

Methods: Case report.

Results: A set of twins, age 7 years, (Twin A and Twin B) with known family history of von Hippel-Lindau disease (gene test positive) and no systemic manifestations were evaluated. Read More

Ophthalmic Epidemiol 2016 7;23(2):122-130. Epub 2016 Mar 7.

Wills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA.

Purpose: The Wills Eye Glaucoma Research Center initiated a 2-year demonstration project to develop and implement a community-based intervention to improve detection and management of glaucoma in Philadelphia.

Methods: The glaucoma detection examination consisted of: ocular, medical, and family history; visual acuity testing; corneal pachymetry; biomicroscopy of the anterior segment; intraocular pressure (IOP) measurement; gonioscopy; funduscopy; automated visual field testing; and fundus-color photography. Treatment included laser surgery and/or IOP-lowering medication. Read More

J Telemed Telecare 2017 Feb 9;23(2):365-370. Epub 2016 Jul 9.

1 Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, MI, USA.

Introduction We compared remote, image-based patient consultations to in-person consultations at emergency department and inpatient hospital settings. Methods Patients evaluated by the ophthalmic consultation services (gold standard) were imaged over a two-week period. A trained study coordinator took anterior segment photographs (AS) and posterior segment photographs (PS) with a portable camera (PictorPlus, Volk Optical, Cleveland, OH). Read More

Ophthalmic Genet 2016 5;37(1):102-8. Epub 2016 Feb 5.

a Wilmer Eye Institute, Johns Hopkins Hospital , Baltimore , MD , USA .

Background: Mutations in BEST1 account for autosomal dominant vitreoretinochoroidopathy (ADVIRC), a rare inherited retinal dystrophy with presenile cataracts and incomplete anterior segment development. The long-term clinical findings and visual prognosis of these patients continues to evolve over time.

Materials And Methods: The retina was assessed by fundus photography, fluorescein angiography, and spectral domain optical coherence tomography. Read More

Retina 2016 May;36(5):1000-8

*Byers Eye Institute, Stanford University School of Medicine, Department of Ophthalmology, Palo Alto, California; †Department of Ophthalmology, Santa Clara Valley Medical Center, San Jose, California; and ‡DigiSight Technologies, Inc., San Francisco, California.

Purpose: To compare clinical assessment of diabetic eye disease by standard dilated examination with data gathered using a smartphone-based store-and-forward teleophthalmology platform.

Methods: 100 eyes of 50 adult patients with diabetes from a health care safety-net ophthalmology clinic. All patients underwent comprehensive ophthalmic examination. Read More

Case Rep Ophthalmol Med 2015 15;2015:592847. Epub 2015 Dec 15.

Osmangazi University Faculty of Medicine, Department of Ophthalmology, Eskişehir, Turkey.

Purpose. To report clinical and in vivo confocal microscopy (IVCM) findings of two patients with ocular ochronosis secondary due to alkaptonuria. Materials and Methods. Read More

Arch Soc Esp Oftalmol 2016 Jan 2;91(1):34-9. Epub 2015 Dec 2.

Servicio de Oftalmología, Hospital General Universitario de Valencia, Valencia, España.

Objective: To describe the clinical findings and its complications in 2 patients with focal choroidal excavation (FCE).

Methods: A retrospective case-series including 4 eyes of 2 patients with FCE that underwent a comprehensive ophthalmological examination including slit-lamp examination, colour fundus photography, spectral-domain optical coherence tomography (SD-OCT), fluorescein angiography (FA), and indocyanine green angiography.

Results: In the 2 patients, both the anterior and posterior segment evaluations were mostly normal despite the of presence yellowish spots in the macular area of the right eye of patient 1, and of a small yellowish elevated lesion with serous macular detachment in the macular area of the left eye in patient 2. Read More

Transplant Proc 2015 Oct;47(8):2544-7

Department of Pathology, 302 Military Hospital of China, Beijing, China.

Gastrointestinal (GI) metastasis of hepatocellular carcinoma is very rare. This is the first report of post-transplantation gastric metastasis. A 43-year-old man with a history of hepatitis B-related hepatocellular carcinoma (HCC) in the right anterior segment of the liver received an orthotopic liver transplant. Read More

Br J Ophthalmol 2016 06 20;100(6):824-8. Epub 2015 Oct 20.

University Children's Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Aims: Juvenile CLN3 disease, one of the most common forms of a group of lysosomal storage diseases called neuronal ceroid lipofuscinoses (NCLs), is a progressive neurodegenerative disorder with initial visual deterioration. The objective of this study was to analyse the retinal phenotype of patients with CLN3 disease with the help of recent ophthalmic imaging modalities to distinguish CLN3 disease from other inherited retinal dystrophies.

Methods: Patients underwent ophthalmic evaluations, including anterior and posterior segment examinations, optical coherence tomography, fundus autofluorescence, near infrared imaging and fundus photography. Read More

Arq Bras Oftalmol 2015 May-Jun;78(3):168-72

Ophthalmology Department, Faculty of Medicine, Balıkesir University, Balıkesir, Turkey.

Purpose: To report the anatomical and visual results in patients diagnosed as having retinal pigment epithelium (RPE) tears after receiving ranibizumab injections.

Methods: Eyes diagnosed as having RPE tears with a minimum 6-month follow-up were retrospectively evaluated. Each eye was treated with at least three doses of ranibizumab at monthly intervals. Read More

Mol Med Rep 2015 Aug 30;12(2):2584-8. Epub 2015 Apr 30.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑Sen University, Guangzhou, Guangdong 510060, P.R. China.

The purpose of the current study was to investigate the 11 bestrophin-1 (BEST1) exons in patients with best vitelliform macular dystrophy (BVMD), and to characterize the associated clinical features. Complete ophthalmic examinations were conducted on two families, and two family members were diagnosed with BVMD. Genomic DNA was extracted from the leukocytes of peripheral blood collected from the patients and their family members, in addition to 100 unrelated control subjects recruited from the same population. Read More

PLoS One 2015 16;10(3):e0120476. Epub 2015 Mar 16.

Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.

Purpose: This paper describes the study design, methodology, cohort profile and self-reported diseases in the ophthalmological branch of the Gutenberg Health Study (GHS).

Methods: The GHS is an ongoing, prospective, interdisciplinary, single-center, population-based cohort study in Germany. The main goals of the ophthalmological section are to assess the prevalence and incidence of ocular diseases and to explore risk factors, genetic determinants and associations with systemic diseases and conditions. Read More

Ophthalmology 2015 Apr 8;122(4):711-20. Epub 2015 Jan 8.

Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

Purpose: To describe the baseline characteristics of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study cohort, the largest African American population with primary open-angle glaucoma (POAG) recruited at a single institution (University of Pennsylvania [UPenn], Department of Ophthalmology, Scheie Eye Institute) to date.

Design: Population-based, cross-sectional, case-control study.

Participants: A total of 2520 African American subjects aged 35 years or more who were recruited from the greater Philadelphia, Pennsylvania area. Read More

Immunol Res 2014 Dec;60(2-3):356-60

Ophthalmology Department, Hospital Clínic de Barcelona, School of Medicine, Universitat de Barcelona, Barcelona, Catalonia, Spain,

Alopecia areata is understood as an autoimmune disease T cell-mediated mainly involving hair follicles in humans. It is a multifactorial aetiologic disease characterised by non-scarring alopecia and asymptomatic areas, affecting approximately 2 % of dermatology patients. Recent studies suggest that the pathogenesis of AA plays an important role in the association of certain HLA groups, neuroendocrine parameters and immunogenic factors. Read More

Vet Ophthalmol 2014 Nov 10;17(6):454-61. Epub 2014 Sep 10.

Centre Hospitalier Vétérinaire, 275 Route Impériale, 74370, Saint-Martin Bellevue, France.

Objective: To describe a means of converting the Kowa RC-2 camera to a digital version.

Procedure: The optic (OP) and the film portions (FP) of the Kowa RC-2 were separated. The lateral rails were unscrewed from the front plate of the FP. Read More

Zhonghua Yan Ke Za Zhi 2014 May;50(5):349-54

Email:

Objective: To investigate the prevalence and characteristics of primary glaucoma in the population of Huamu community, Shanghai.

Methods: It was a population-based cross-section study.Using random cluster sampling method, 3 neighborhood committees were randomly selected from Huamu community. Read More