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Neuropsychiatr 2021 Jun 15. Epub 2021 Jun 15.

Eating Disorders National Service, South London and Maudsley NHS Foundation Trust, London, UK.

Background: The wellbeing of patients with eating disorders is one of the priorities in the "bigger picture" of treatment for eating disorders. Sensory soothing strategies for sensory sensitivities are supportive tools which could be useful in day-care and inpatient clinical programmes.

Methods: Evaluation of multiple separate sensory wellbeing workshops consisting of psychoeducation and experiential components delivered in inpatient and intensive day-care services was performed. Read More

Borderline Personal Disord Emot Dysregul 2021 Jun 14;8(1):20. Epub 2021 Jun 14.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, Margarete-Hoeppel-Platz 1, 97080, Wuerzburg, Germany.

Context: Third-wave therapies have demonstrated efficacy as a treatment option for EDs in adulthood. Data on the suitability for EDs in adolescence are lacking.

Objective: To estimate the efficacy of third-wave interventions to reduce ED symptoms in adolescents in randomized controlled trials (RCTs) and uncontrolled studies. Read More

Psychiatry Res 2021 Jun 6;302:114045. Epub 2021 Jun 6.

Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany; Schoen Clinic Roseneck, Prien am Chiemsee, Germany; Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, Freiburg, Germany.

Objective: People with mental disorders might be differentially affected by the COVID-19 pandemic. The aim of the current study was to evaluate the impact of the pandemic on patients with various psychiatric disorders who were admitted to inpatient treatment.

Methods: Five-hundred thirty-eight inpatients with mental disorders participated in a survey about psychological consequences of the pandemic between March-December 2020. Read More

J Behav Cogn Ther 2021 Mar 3;31(1):57-66. Epub 2021 Mar 3.

Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, USA 75390-9070.

Eating disorders (EDs) are characterized by altered eating behaviors and valuation of self-image, as well as difficulty establishing supportive social relationships. This pilot study evaluated feasibility, acceptability, and clinical responses to a novel and brief group-therapy intervention for EDs, the Self-Blame and Perspective-Taking Intervention (SBPI). The SBPI consisted of four sessions of experiential art therapy activities in conjunction with psychoeducation targeting interpersonal attributions and mentalization. Read More

Bio Protoc 2021 May 5;11(9):e4009. Epub 2021 May 5.

Department of Psychology, Hunter College, CUNY, New York, NY, USA.

Activity-based anorexia (ABA) is a widely used rodent model of anorexia nervosa. It involves combining limited access to food with unlimited access to a running wheel, leading to a paradoxical decrease in food intake, hyperactivity, and life-threatening weight loss. Although initially characterized in rats, ABA has been tested in mice with results that vary based on strain, sex, age, the amount of time food is available, and the number of days of food restriction. Read More

Front Psychiatry 2021 28;12:698194. Epub 2021 May 28.

Charles Perkins Centre, InsideOut Institute, University of Sydney, Camperdown, NSW, Australia.

Front Psychiatry 2021 28;12:653482. Epub 2021 May 28.

Child and Adolescent Psychiatric Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy.

Medical and psychiatric complications and treatment compliance are important considerations in determining the treatment program for patients with severe anorexia nervosa (AN). Clinical practice guidelines agree that an outpatient program is the first choice for the treatment of most eating disorders, but vary in supporting these programs for AN. However, inpatient care is known to be costly and the risk of relapse and readmission is high. Read More

J Eval Clin Pract 2021 Jun 14. Epub 2021 Jun 14.

Philosophy Department, University of Massachusetts Boston, Boston, Massachusetts, USA.

Introduction: ICD-11's diagnostic definition possesses conceptual lacunae and normative implications calling for further attention.

Method: Assumptions underlying it and their ethical implications, are examined employing philosophical analysis; particularly, these are (1) changes to eliminate implications of voluntary agency to caloric restriction; (2) definitions of "dangerously low weight;" and (3) disorder boundaries as stated in qualifications and exclusions.

Results: (1) The extent to which AN behaviour can be acknowledged to be driven by forces out of, or limiting, voluntary control is unresolved; this is illustrated using the contested part played by excessive exercise, clarification of which requires understanding of AN motivation. Read More

Am J Case Rep 2021 Jun 14;22:e930840. Epub 2021 Jun 14.

Department of Endocrinology and Research, Total Lipedema Care, Los Angeles, CA, USA.

BACKGROUND Lipedema is a loose connective tissue disease that causes disproportionate subcutaneous fat accumulation on the extremities. As a result of the increased subcutaneous tissue accumulation, lipedema is often confused with obesity by both physicians and patients. Poor awareness and limited diagnosis of lipedema contribute to the confusion of lipedema with obesity and can lead to decreased body image acceptance. Read More

Ugeskr Laeger 2021 Jun;183(23)

A 39-year-old woman with severe anorexia nervosa, complicated with a low ejection fraction of 10-20%, developed refeeding syndrome, massive oedema, and acute cardiac failure, but recovered during specialised nutritive treatment and inotropic medication with levosimendan. With this case report, we aim to draw attention to the refeeding syndrome and to the cardiological consequences of anorexia nervosa. Takotsubo cardiomyopathy is reversible if the proper treatment is given. Read More

J Psychiatr Res 2021 Jun 1;140:267-281. Epub 2021 Jun 1.

Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

The utility of cannabinoids and cannabinoid-based products (CBPs) as a pharmacological aid to treat psychiatric disorders in adulthood is still poorly understood despite a number of comprehensive general reviews discussing the topic. With a focus on randomized controlled trial (RCT) data, this review and meta-analysis aimed to aggregate and evaluate all current high-quality (Level-1) research that specifically assessed the effectiveness of a CBP on a diagnosed adult psychiatric disorder. The following databases, from their inception to September 2020, were included in the search: Academic Search Premier, PubMed, Ovid MEDLINE®, Web of Science™, PsycARTICLES, PsycINFO, CINAHL (Nursing and Allied Health), and Scopus. Read More

Eur Eat Disord Rev 2021 Jun 12. Epub 2021 Jun 12.

Department of Neuroscience, University of Padova, Padova, Italy.

Objective: Cognitive remediation therapy (CRT) has been proposed as an add-on treatment approach that could increase the engagement in treatment of anorexia nervosa (AN) patients and reduce maintaining factors, but prior studies have evaluated CRT in individual and group settings, difficult protocols for rehabilitation settings. Our aim is to evaluate the CRT rolling protocol implementation in an inpatient specialised unit.

Methods: A historical longitudinal controlled study was designed to include 31 AN patients for the CRT program, and 28 AN patients treated as usual. Read More

Ann Noninvasive Electrocardiol 2021 Jun 11:e12865. Epub 2021 Jun 11.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

Introduction: The risk of cardiovascular death is increased in patients with eating disorders (ED), but the background for this is unknown. Early repolarization pattern (ERP) on the electrocardiogram (ECG) has been associated with increased risk of sudden cardiac death.

Methods: We investigated the prevalence of ERP in 233 female patients with anorexia nervosa (AN) and bulimia nervosa (BN) (age 18-35 years) compared with 123 healthy female controls. Read More

Front Psychol 2021 25;12:670436. Epub 2021 May 25.

Department of Psychology, Friedrich-Alexander University, Erlangen, Germany.

Front Psychiatry 2021 25;12:537379. Epub 2021 May 25.

Institute of Biomedical Ethics and History of Medicine, University of Zurich, Zurich, Switzerland.

Some psychiatric patients develop severe and persistent mental illness (SPMI), which, for a variety of reasons, can be therapy-refractory. Sometimes, treatment is not considered helpful by the patients themselves and does not improve their subjective quality of life. Furthermore, many SPMI patients experience compulsory interventions such as seclusion, restraint, or treatment against their will, which can cause harm. Read More

Sci Rep 2021 Jun 10;11(1):12262. Epub 2021 Jun 10.

Laureate Institute for Brain Research (LIBR), Tulsa, OK, USA.

Body image disturbance (BID) is a core feature of eating disorders, for which there are few objective markers. We examined the feasibility of a novel digital tool, "Somatomap", to index BID related to anorexia nervosa (AN) severity. Fifty-five AN inpatients and 55 healthy comparisons (HC) outlined their body concerns on a 2-Dimensional avatar. Read More

Clin Psychol Psychother 2021 Jun 10. Epub 2021 Jun 10.

Department of Psychology, Bar Ilan University, Israel.

Objective: This study had two goals. The first was to validate and examine the potential of the Hebrew version of the Cambridge Mindreading face task (CAM )-an ecological measure of emotional theory of mind (eToM)-to assess eToM in individuals with anorexia nervosa (AN). The second goal was to examine whether interpersonal mistrust would mediate the relation between mentalizing and eToM and the severity of AN. Read More

Front Psychiatry 2021 24;12:654589. Epub 2021 May 24.

Eating Disorders Department, Maayanei Hayeshuah Medical Center, Bnei Brak, Israel.

With the outbreak of the COVID-19 pandemic, the need arose to maintain treatment continuity for religious Jewish Ultra-Orthodox young women with eating disorders (EDs) previously hospitalized in the ED department at the Ultra-Orthodox "Mayanei Hayeshua" medical center in Israel. This need led to the development of home-based online treatment channels, previously unfamiliar, and unaccepted in this population. The implementation of this model had to take into consideration many of the difficulties inherent in the use of online treatment in Jewish Ultra-Orthodox mental health patients. Read More

J Eat Disord 2021 Jun 9;9(1):66. Epub 2021 Jun 9.

School of Psychology, University College Dublin, Dublin, Ireland.

Background: Resilience research to date has been criticised for its consideration of resilience as a personal trait instead of a process, and for identifying individual factors related to resilience with no consideration of the ecological context. The overall aim of the current study was to explore the multi-level process through which adults recovering from EDs develop resilience, from the perspectives of clients and clinicians. The objective of this research was to outline the stages involved in the process of developing resilience, which might help to inform families and services in how best to support adults with EDs during their recovery. Read More

J Eat Disord 2021 Jun 9;9(1):67. Epub 2021 Jun 9.

Department of General Practice & Primary Healthcare, Faculty of Medical & Health Sciences, University of Auckland, Auckland, New Zealand.

Recovery and remission rates of adolescent anorexia nervosa (AN) following Family Based Treatment (FBT) have seen a relative decline over recent years. While reasonably successful in achieving physical recovery (i.e. Read More

Hosp Pediatr 2021 Jun 8. Epub 2021 Jun 8.

Departments of Pediatrics and Psychiatry and Behavioral Sciences, University of California, San Francisco, California

Pediatric patients with anorexia nervosa and atypical anorexia nervosa may present to hospitals with significant vital sign instability or serum laboratory abnormalities necessitating inpatient medical hospitalization. These patients require specialized care, numerous resources, and interdisciplinary collaboration during what can be a protracted admission. Recent evidence informs areas in which care can be accelerated, and published protocols from major children's hospitals are helpful roadmaps to creating a streamlined hospitalization. Read More

Int J Eat Disord 2021 Jun 8. Epub 2021 Jun 8.

Department of Psychology, Michigan State University, East Lansing, Michigan, USA.

Objective: This study explored treatment experiences and social support among individuals with eating disorders (EDs) in mainland China.

Method: Subscribers of a Chinese online social media platform (WeChat) focused on EDs were invited to complete a screening questionnaire that included the Eating Disorder Diagnostic Scale for the DSM-5. Of the 116 questionnaire responses, 31 met inclusion criteria for follow-up interviews. Read More

Exp Ther Med 2021 Aug 26;22(2):804. Epub 2021 May 26.

Department of Endocrinology, Clinical County Hospital, 400000 Cluj-Napoca, Romania.

Anorexia nervosa is an eating disorder characterized by restrictive eating and an intense fear of gaining weight. It is a disease with an increasing incidence during the last few decades, and represents a complex psychiatric condition which includes secondary amenorrhea, nutritional and metabolic damage, and impaired endocrine panel up to bone loss as well as cardiac, gastrointestinal and hematological complications. This is a narrative review which includes an update on this eating disorder from the perspective of an endocrine panel of anomalies, especially of the skeleton, considering the pressure of the recent global COVID-19 pandemic changes. Read More

Front Psychiatry 2021 21;12:632418. Epub 2021 May 21.

Department of Endocrinology and Metabolism and the Institute of Endocrinology, The First Hospital of China Medical University, Shenyang, China.

Eating disorders, including anorexia nervosa (AN) and bulimia nervosa (BN), are complex mental disorders. A better understanding of the burden of eating disorders is essential for improving their management. Information about the burden of eating disorders at the national level in China remains unclear. Read More

Cardiol Young 2021 Jun 7:1-4. Epub 2021 Jun 7.

Department of Pediatric Cardiology, Hospital de Niños Roberto del Rio, Santiago, Chile.

Background: Anorexia nervosa has a prevalence of 0.5-3% in adolescents, placing this population at increased risk of cardiac anomalies including arrhythmias, pericardial effusion, and myocardial dysfunction. Our objective is to describe cardiovascular anomalies observed by tissue Doppler imaging in patients with anorexia nervosa. Read More

Eat Weight Disord 2021 Jun 5. Epub 2021 Jun 5.

Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università, 30, 00185, Rome, RM, Italy.

Numerous studies addressed the topic of behavioral and symptomatic changes in eating disorders. Rates of transition vary widely across studies, ranging from 0 to 70.8%, depending on the diagnoses taken into account and the study design. Read More

Orv Hetil 2021 06 6;162(23):905-910. Epub 2021 Jun 6.

3 Semmelweis Egyetem, Általános Orvostudományi Kar, I. Gyermekgyógyászati Klinika, Budapest.

Összefoglaló. A divatiparra vonatkozó egészségvédelmi szabályozások hiányosak. A karcsúság elérését célzó szociokulturális nyomás a divatiparon belül fokozott, a divatmodelleket gyakran késztetik kórosan alacsony testsúly elérésére, ami pszichológiai abúzusnak felel meg. Read More

J Eat Disord 2021 Jun 4;9(1):65. Epub 2021 Jun 4.

Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Canada.

Background: There is a noticeable lack of evidence regarding the impact of COVID-19 and the associated lockdown on young people with eating disorders. The goals of this study were 1) to examine characteristics of adolescents presenting for eating disorder (ED) assessment since the onset of the COVID-19 pandemic; 2) to compare adolescents presenting for ED assessment since the onset of the COVID-19 pandemic to those that presented for assessment 1 year previously; 3) to examine implications of the pandemic on the system of care.

Methods: A retrospective chart review was completed on all patients assessed at a pediatric tertiary care ED program during the pandemic between April 1 and October 31, 2020, and on youth assessed during the same time frame 1 year previously. Read More

Eur Eat Disord Rev 2021 Jun 4. Epub 2021 Jun 4.

Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Objectives: The prevalence of eating disorders is rising worldwide. The low body weight in anorexia nervosa as well as the increase in body mass index due to binge eating disorder are contributing to a strikingly high morbidity and mortality. In a similar pattern, the prevalence and burden of the disease of functional gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome is increasing. Read More

Surg Neurol Int 2021 19;12:169. Epub 2021 Apr 19.

Department of Basic Sciences, Touro University Nevada College of Osteopathic Medicine, Henderson, Nevada, United States.

Background: Deep brain stimulation (DBS) has demonstrated preliminary success as a treatment for neuropsychological disorders including obsessive-compulsive disorder and substance use disorder. This systematic review aims to assess the use of DBS in treating eating disorders (EDs) to determine its utility and the extent of adverse effects.

Methods: A PubMed search following PRISMA guidelines was executed to find studies encompassing DBS as a treatment of ED. Read More