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Prev Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131 Mainz, Germany.

Eating disorders are difficult to treat and often associated with morbidity and mortality. Universal prevention approaches are increasingly focusing on enhancing skills, but few eating disorder programs are available for under-15-year-olds. This study aimed to develop and examine a school-based universal prevention program ('MaiStep') for adolescent boys and girls. Read More

J Clin Psychol 2019 Apr 20. Epub 2019 Apr 20.

Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary.

In eating disorders, the denial of the illness is a central phenomenon. In the most severe forms of anorexia, compulsory treatment may be necessary. The professional acceptance of involuntary treatment is controversial due to the fact that the autonomy of the patient is juxtaposed with the obligation of the health care practitioner to save lives. Read More

J Clin Psychol 2019 Apr 20. Epub 2019 Apr 20.

Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, NY.

Although historical descriptions date back to the Hellenistic era, and Gull's naming of anorexia nervosa as a medical disorder to the late 19th century, it is only in the past 50 years that eating disorders have become widely recognized as the prevalent, potentially fatal, complex, and confounding biopsychosocial illnesses we confront today. This paper reviews the considerable advancements in our knowledge of eating disorders during three time periods: the "early years" of the 1960s and 1970s; the "middle years" of the 1980s and 1990s; and the 21st century to date. The recent Diagnostic and Statistical Manual of Mental Disorders, 5th Edition describes six major feeding and eating disorders. Read More

Evid Based Ment Health 2019 Apr 19. Epub 2019 Apr 19.

Cotswold House, Oxford Health NHS Foundation Trust Adult Mental Health Services, Oxford, Oxfordshire, UK.

Bed rest is commonly used on medical and paediatric wards as part of nursing management of the physically compromised patient with severe anorexia nervosa. The aim of this study was to review the evidence base of bed rest as an intervention in the management of severe anorexia nervosa. We searched MEDLINE, PubMed, Embase, PsychInfo, CINAHL, HMIC, AMED, HBE, BNI and guidelines written in English until April 2018 using the following terms: bed rest and anorexia nervosa. Read More

Asian J Psychiatr 2019 Mar 28;42:94-103. Epub 2019 Mar 28.

Department of Psychiatry, Dr Ram Manohar Lohia Hospital PGIMER, New Delhi, India.

Meningioma is a slow-growing benign tumor arising from meninges and is usually asymptomatic. Though neuropsychiatric symptoms are common in patients with brain tumors, they often can be the only manifestation in cases of meningioma. Meningiomas might present with mood symptoms, psychosis, memory disturbances, personality changes, anxiety, or anorexia nervosa. Read More

J Clin Psychol 2019 Apr 17. Epub 2019 Apr 17.

Medical School, Chaim Sheba Medical Center, Tel Hashomer, Israel.

The aim of this introduction to this issue is to review and summarize significant new psychological perspectives and psychotherapeutic interventions in the treatment of eating disorder (EDs). In this issue, five novel therapeutic strategies for the treatment of EDs are presented. These include a combination of psychodynamic psychotherapy and neuropsychology, two recent modifications of cognitive behavioral therapy (the MANTRA, and the conceptualization of change in patients with ED in terms of sense of agency), a specific group movement therapy, and an innovative rehabilitation treatment. Read More

J Psychiatry Neurosci 2019 Apr 17;44(3):1-16. Epub 2019 Apr 17.

From the Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden (Gaudio, Olivo, Schiöth); the Centre for Integrated Research, Area of Diagnostic Imaging, Universita Campus Bio-Medico di Roma, Rome, Italy (Gaudio); the Department of Physiology and Pharmacology, Neuroimaging Laboratory, Sapienza University, Rome, Italy (Carducci, Piervincenzi); and the Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia (Schiöth).

Background: Anorexia nervosa and bulimia nervosa are complex mental disorders, and their etiology is still not fully understood. This paper reviews the literature on diffusion tensor imaging studies in patients with anorexia nervosa and bulimia nervosa to explore the usefulness of white matter microstructural analysis in understanding the pathophysiology of eating disorders.

Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify diffusion tensor imaging studies that compared patients with an eating disorder to control groups. Read More

Psychother Psychosom 2019 Apr 16:1-3. Epub 2019 Apr 16.

Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Appetite 2019 Apr 12;139:35-41. Epub 2019 Apr 12.

Department of Psychiatry, Columbia University Irving Medical Center, NY, NY, USA; Department of Psychiatry, New York State Psychiatric Institute, NY, NY, USA.

Fat restriction is a characteristic eating behavior among individuals with anorexia nervosa (AN), and laboratory meal studies demonstrate restricted fat intake among low-weight patients. The Geiselman Food Preference Questionnaire-I (FPQ) is a validated self-report measure that yields a fat preference score (FPS). Prior research reported that patients with AN had a significantly lower FPS than did healthy control (HC) participants. Read More

Endocrinol Diabetes Nutr 2019 Apr 10. Epub 2019 Apr 10.

Immunonutrition Research Group, Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN) - CSIC, C/José Antonio Novais 10, 28040 Madrid, Spain. Electronic address:

Introduction: Psychological and neuroendocrine alterations are typical characteristics in anorexia nervosa patients. The role of adipokines and cytokines as mediators of body systems' adaptations to the patients' abnormal eating behavior is not well understood. The duration of disease seems to be a determinant of nutritional status and associated hormone changes. Read More

Physiol Behav 2019 Apr 10;206:185-190. Epub 2019 Apr 10.

Department of Psychiatry, University of Colorado Anschutz Medical Campus, School of Medicine, Aurora, CO, USA.

Anorexia nervosa is a severe psychiatric illness with high mortality. Brain imaging research has indicated altered reward circuits in the disorder. Here we propose a disease model for anorexia nervosa, supported by recent studies, that integrates psychological and biological factors. Read More

Psychol Med 2019 Apr 12:1-2. Epub 2019 Apr 12.

Section of Eating Disorders, Department of Psychological Medicine,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.

Eat Weight Disord 2019 Apr 11. Epub 2019 Apr 11.

Child and Adolescent Psychopathology Unit, Salvator University Hospital, Public Assistance-Marseille Hospitals, Aix-Marseille University, 249 Boulevard Sainte-Marguerite, 13009, Marseille, France.

Purpose: Assessment of the symptoms of body image disorder (BID) is crucial in anorexia nervosa (AN). Recent technological advancements such as virtual reality (VR) have improved the visual perception with 3D avatars and the feeling to be the avatar with the immersive conditions. This retrospective study examines the hypothesis that VR with standardized 3D avatars would improve body image perception and then body image evaluation by adolescents with AN, compared to the paper-based figure rating scales (FRS). Read More

Fertil Steril 2019 Apr 8. Epub 2019 Apr 8.

Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah.

BMC Psychiatry 2019 Apr 11;19(1):111. Epub 2019 Apr 11.

Division of Psychiatry Research and Psychogeriatric Medicine, Psychiatric University Hospital Zurich, Lenggstrasse 31, 8008, Zurich, Switzerland.

Background: Some patients develop severe and persistent mental illness (SPMI) which is therapy-refractory. The needs of these patients sometimes remain unmet by therapeutic interventions and they are at high risk of receiving care that is inconsistent with their life goals. Scholarly discourse has recently begun to address the suitability of palliative care approaches targeting at enhancing quality of life for these patients, but remains to be developed. Read More

Front Psychol 2019 26;10:580. Epub 2019 Mar 26.

Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, Netherlands.

Body image disturbance is a core characteristic of anorexia nervosa, which might be grounded in distortions in schematic body representations. In line with this, several studies showed that when walking through door-like apertures of different widths, individuals with anorexia nervosa move as if their bodies are larger than they actually are. They turn their body at a higher aperture/shoulder width ratio than healthy individuals. Read More

Front Psychiatry 2019 26;10:159. Epub 2019 Mar 26.

Basic Medical Sciences Neuroscience and Sense Organs Department, University of Bari Aldo Moro, Bari, Italy.

Over the last few years, new studies focused their attention on the gender-related features in high-functioning autism spectrum disorder (HFA), often leading to controversial results. Another interesting aspect of these subtype of patients is linked to the complexity of clinical presentation, where besides core symptoms, other co-occurrence disorders may complicate the diagnostic evaluation. Therefore, we retrospectively studied 159 HFA patients, male and female, investigating their comorbidities and to find any gender difference. Read More

Eur Eat Disord Rev 2019 Apr 9. Epub 2019 Apr 9.

Department of Psychology, University of Salzburg, Salzburg, Austria.

Reduced perception of bodily signals and low levels of intuitive eating have been reported in patients with anorexia nervosa (AN) compared with normal-weight individuals. However, findings have been inconsistent and treatment progress might account for some of these inconsistencies. Thirty-seven inpatients with AN and 39 normal-weight controls completed a heartbeat perception task and the Intuitive Eating Scale-2. Read More

Front Psychol 2019 22;10:587. Epub 2019 Mar 22.

Faculty of Psychology, Southwest University, Chongqing, China.

Eat Weight Disord 2019 Apr 8. Epub 2019 Apr 8.

Schneider Children's Medical Center, Petah Tikva, Israel.

Purpose: The aim of this study was to investigate the predictive value of early changes in depression levels during inpatient treatment of adolescent anorexia nervosa (AN).

Methods: Fifty-six adolescents (88% girls) aged 10-18 years (M = 15.35, SD = 2. Read More

Nutrients 2019 Apr 5;11(4). Epub 2019 Apr 5.

Nutrition Unit, Raymond Poincaré University Hospital (Assistance Publique⁻Hôpitaux de Paris), 92380 Garches, France.

Introduction: Anorexia nervosa (AN) is a complex psychiatric disorder, which can lead to specific somatic complications. Undernutrition is a major diagnostic criteria of AN and it can be associated with several micronutrients deficiencies.

Objectives: This study aimed to determinate the prevalence of micronutrients deficiencies and to compare the differences between the two subtypes of AN (restricting type (AN-R) and binge-eating/purging type (AN-BP)). Read More

Clin Nutr 2019 Mar 23. Epub 2019 Mar 23.

Institute of Microbiology, Czech Academy of Sciences, Videnska 1083, Prague 4, Czech Republic.

Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a devastating fear of weight gain, and body image disturbance, however the etiopathogenesis remains unclear. The objective of the article is to provide a comprehensive review on the potential role of gut microbiota in pathogenesis of anorexia nervosa. Recent advances in sequencing techniques used for microbial detection revealed that this disease is associated with disruption of the composition of normal gut microbiota (dysbiosis), manifested by low microbial diversity and taxonomic differences as compared to healthy individuals. Read More

Psychiatry Res 2019 Mar 28;275:269-275. Epub 2019 Mar 28.

Psychiatry Unit, Department of Health Sciences, University of Florence, Italy.

The etiopathogenesis of eating disorders (EDs) is complex and still not well understood. Biological, psychological and environmental factors (e.g. Read More

Int Rev Psychiatry 2019 Apr 5:1-15. Epub 2019 Apr 5.

a Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience , King's College London , London , UK.

The eating disorder clinical and scientific community advocates for the use of a shared approach to healthcare that actively involves patients and carers. A systematic review of the literature on guided self-help or self-help in anorexia nervosa (targeting either the individual affected by the illness or their carers) and meta-analyses of studies using randomised controlled designs for the evaluation of the outcomes: (1) drop-out from end-of-treatment assessment, (2) body mass index (BMI), (3) anxiety, (4) depression and (5) quality of life, were undertaken. Guided self-help was directed to patients in 15 studies and to carers in seven studies. Read More

Biochimie 2019 Apr 1. Epub 2019 Apr 1.

INRS-Institut Armand-Frappier, 531, Boulevard des Prairies, Laval, QC, H7V 1B7, Canada; Center for Interdisciplinary Research on Well-Being, Health, Society and Environment (Cinbiose), Université Du Québec à Montréal, C.P.8888, Succ. Centre-Ville, Montréal, QC, H3C 3P8, Canada. Electronic address:

We have reviewed the scientific literature related to four diseases in which to serotonin (5-HT) is involved in the etiology, herein named 5-HT-linked diseases, and whose prevalence is influenced by estrogenic status: depression, migraine, irritable bowel syndrome and eating disorders. These diseases all have in common a sex-dimorphic prevalence, with women more frequently affected than men. The co-occurrence between these 5-HT-linked diseases suggests that they have common physiopathological mechanisms. Read More

Int J Eat Disord 2019 Apr 4. Epub 2019 Apr 4.

Faculty of Health, Deakin Child Study Centre, School of Psychology, Deakin University, Burwood, Victoria, Australia.

Objective: Attention-deficit/hyperactivity disorder (ADHD) is associated with increased eating disorder symptoms, yet little research examining this association has taken a diagnostic approach using a population-based sample. This cross-sectional study examined differences in DSM-5 eating disorder symptoms and partial-syndrome diagnoses at 14-15 years of age in adolescents with and without ADHD in a population-based sample.

Method: This study uses data from waves 1, 5 and 6 of the Longitudinal Study of Australian Children (N = 2,672). Read More

Praxis (Bern 1994) 2019 ;108(5):307-313

1 Klinik für Präventivzahnmedizin, Parodontologie und Kariologie, Zentrum für Zahnmedizin, Universität Zürich.

Tooth Erosions Associated with Gastroesophageal Reflux: Cause, Prevention and Restorative Therapy Abstract. Dental erosions are caused by the recurring contact of solutions which are unsaturated in tooth minerals,ith hard tooth substances. This initially leads to softening and later to an irreversible loss of hard tooth substance. Read More

Analyst 2019 Apr 2. Epub 2019 Apr 2.

Department of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey.

Adipocyte hypertrophy and hyperplasia are important parameters in describing abnormalities in adipogenesis that are concomitant to diseases such as obesity, diabetes, anorexia nervosa and osteoporosis. Therefore, technical developments in the detection of adipocytes become an important driving factor in adipogenesis research. Current techniques such as optical microscopy and flow cytometry are available in detection and examination of adipocytes, driving cell- and molecular-based research of adipogenesis. Read More

Complement Ther Med 2019 Apr 31;43:176-180. Epub 2019 Jan 31.

School of Medicine, Western Sydney University, Sydney, Australia; Translational Health Research Institute, Western Sydney University, Sydney, Australia.

Objectives: The purpose of this study was to investigate the perception of Complementary Medicines (CMs) in community women; to identify which CM approaches people perceived as the most beneficial; and the impact of Eating Disorder (ED) symptoms on one's perception of treatment.

Design & Setting: Electronic and paper-based surveys were distributed to a pre-existing cohort of community women (n = 100) aged 18 years and over. The survey included questions about the perception of CMs' benefits in EDs regarding a vignette of a women with Anorexia Nervosa (AN), and whether CMs helped the participant's own personal health. Read More

Nutrition 2018 Nov 25;63-64:87-91. Epub 2018 Nov 25.

Unidad de Nutrición Clínica, Servicio de Medicina Interna, Hospital Universitario de Burgos, Burgos, Spain.

Objectives: Anorexia nervosa (AN) is a complex disease that involves malnutrition and a profound depletion in muscle mass. The thickness of the adductor pollicis muscle (APM) has been proposed as a new anthropometric technique to estimate muscle mass, check early changes, and assess its evaluation. This study aimed to evaluate the accuracy and validity of the APM thickness in a cohort of malnourished patients with AN when checking local mass gain. Read More

Psychiatr Genet 2019 Mar 28. Epub 2019 Mar 28.

Clinique des maladies mentales et de l'encéphale, Hôpital Sainte-Anne, Université Paris-Descartes.

Background: Anorexia nervosa is a complex neuropsychiatric disorder presenting with life-threatening low body weight, and a persistent fear of gaining weight. To date, no whole exome sequencing was performed in male individuals with anorexia nervosa.

Aim And Methods: Here, we performed an exome analysis in two independent families with male individuals with anorexia nervosa and found variants in the Neuronatin (NNAT) gene in both probands. Read More

Ugeskr Laeger 2019 Mar;181(12)

This is a case report of a 51-year-old woman with bilateral stress fractures of the pelvic rami and a history of anorexia nervosa (AN). AN is a psychiatric condition of low weight caused by restricted food intake, impaired body image and an exaggerated fear of gaining weight in addition to compensating behaviour such as excessive physical activity. Among patients with AN, reduced bone density is common, and a higher risk of fractures is present. Read More

Australas Psychiatry 2019 Apr 1:1039856219839477. Epub 2019 Apr 1.

Research Fellow, Department of Psychiatry, The University of Melbourne, Melbourne, VIC, and; Centre for Mental Health, Swinburne University, Hawthorn, VIC, and; Department of Psychiatry, St. Vincent's Mental Health, Melbourne, VIC, and; Department of Optometry and Vision Sciences, The University of Melbourne, Melbourne, VIC, and; Department of Mental Health, Austin Hospital, Melbourne, VIC, Australia.

Objectives:: Anorexia nervosa and body dysmorphic disorder share a hallmark clinical feature of severe body image disturbance. This study aimed to document major demographic and clinical characteristics in anorexia nervosa versus body dysmorphic disorder, and it was the first to compare specific body parts related to body image dissatisfaction across these disorders directly.

Methods:: Anorexia nervosa ( n=26) and body dysmorphic disorder ( n=24) patients were administered a range of clinical measures, including key questions about the specificities of their body image concerns. Read More

Int J Ment Health Nurs 2019 Mar 31. Epub 2019 Mar 31.

Australian Catholic University and Northern Sydney Local Health District, North Sydney, New South Wales, Australia.

Nurses caring for adolescent consumers with anorexia nervosa in the inpatient setting are challenged in a unique way, in that they are caring for people with whom they do not have a mutually held concept of well-being. Their efforts to ensure weight gain are frequently against the wishes of the consumer. This dissonance results in challenging interactions, where nursing care and authority may be undermined. Read More

Front Psychol 2019 15;10:555. Epub 2019 Mar 15.

Athena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

Orthorexia nervosa (ON) is a condition that is characterized by a pathological obsession with eating foods one considers healthy and has recently been suggested as a new possible diagnosis. However, there is limited published research on health professionals' recognition, ideas and opinions regarding the diagnosis and classification of ON. The aim of this mixed-methods study was to gain insight into the perspectives of clinically active health professionals on ON, and into their opinions on if and how the disorder should be classified. Read More

Fertil Steril 2019 Mar 25. Epub 2019 Mar 25.

Department of Emergency and Post-Emergency of Psychiatric, CHU Montpellier, University of Montpellier, INSERM, Montpellier, France.

Objective: To evaluate the potentially protective effects of oral contraceptives (OC) on bone loss in a large population of young women with anorexia nervosa (AN).

Design: Cross-sectional study.

Setting: University hospital. Read More

Int J Eat Disord 2019 Mar 28. Epub 2019 Mar 28.

Eating Disorder Unit, Mental Health Center Ballerup, Copenhagen, Denmark.

Objective: Alterations in blood lipid concentrations in anorexia nervosa (AN) has been reported; however, the extent, mechanism, and normalization with weight restoration remain unknown. We conducted a systematic review and a meta-analysis to evaluate changes in lipid concentrations in acutely-ill AN patients compared with healthy controls (HC) and to examine the effect of partial weight restoration.

Method: A systematic literature review and meta-analysis (PROSPERO: CRD42017078014) were conducted for original peer-reviewed articles. Read More

Int Rev Psychiatry 2019 Mar 27:1-9. Epub 2019 Mar 27.

a South London and Maudsley NHS Foundation Trust , Bethlem Royal Hospital , Kent , United Kingdom.

Admissions and re-admissions for inpatient care for anorexia nervosa have been increasing. The aim of this study was to examine whether the transition from inpatient care to the community could be facilitated by supplementing usual treatment with ECHOMANTRA (transition interventions) for both patients and carers. A case series study was employed using a mixed-methods approach to measure the feasibility and efficacy of augmenting intensive hospital treatment with ECHOMANTRA. Read More

Front Endocrinol (Lausanne) 2019 12;10:108. Epub 2019 Mar 12.

Obesity Management Center, Institute of Endocrinology, Prague, Czechia.

Anti-lipolytic drugs and exercise are enhancers of growth hormone (GH) secretion. Decreased circulating free fatty acids (FFA) have been proposed to exert ghrelin-GH feedback loop after administration of an anti-lipolytic longer-acting analog of nicotinic acid, Acipimox (OLB, 5-Methylpyrazine-2-carboxylic acid 4-oxide, molecular weight of 154.1 Da). Read More

Int J Eat Disord 2019 Mar 26. Epub 2019 Mar 26.

Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Objective: Attention processing for food may be biased in people with Anorexia Nervosa (AN). However, previous studies have had inconsistent results. This is likely to be due to indirect assessment of attention, which does not inform on the underlying attention processes, and/or the heterogeneity of participants across studies, testing either adults or adolescents with AN, that is, people at very different developmental and illness stages. Read More

Br J Psychiatry 2019 Mar 22:1-3. Epub 2019 Mar 22.

Professor and Head,The Centre for Psychiatry,Wolfson Institute of Preventive Medicine,Barts and The London School of Medicine & Dentistry,Queen Mary University of London;and Honorary Consultant Psychiatrist,East London NHS Foundation Trust,UK.

SummarySchizophrenia and anorexia nervosa were recently added to the list of conditions for which whole genome sequencing might be indicated as part of the 100 000 Genomes Project, reflecting the remarkable recent progress in findings emerging from psychiatric genetics research. Genetic testing methods may offer increased opportunities for diagnosis and estimation of familial risk and could have implications for management and treatment options. They also present ethical and philosophical questions about the role of testing and storage of genetic information. Read More

Eat Weight Disord 2019 Mar 21. Epub 2019 Mar 21.

Centre for Exercise, Nutrition and Health Sciences, School of Policy Studies, University of Bristol, Bristol, BS8 1TZ, UK.

Purpose: Compulsions surrounding restrictive eating, exercise, and weight monitoring are thought to maintain abnormal eating behaviour in individuals with anorexia nervosa (AN). This study aimed to determine if AN psychopathology and trait anxiety explain the presence of restrictive eating, exercise, and weight monitoring compulsions in a mixed sample.

Methods: Participants were 31 females with AN and 31 age and gender-matched healthy individuals (HC). Read More

Int J Eat Disord 2019 Mar 20. Epub 2019 Mar 20.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Objective: The fetal programming model hypothesizes that developmental programming in utero and in early life induces adaptations that predetermine the adult phenotype. This study investigated whether prenatal/perinatal complications are associated with lifetime eating disorders in women.

Method: Participants included 46,373 adult women enrolled in the Norwegian Mother and Child Cohort Study (den norske Mor & barn-undersøkelsen [MoBa]). Read More

Front Psychol 2019 4;10:219. Epub 2019 Mar 4.

Salmons Centre for Applied Psychology, Canterbury Christ Church University, Canterbury, United Kingdom.

In this paper, we argue that Anorexia Nervosa (AN) can be explained as arising from a 'lost sense of emotional self.' We begin by briefly reviewing evidence accumulated to date supporting the consensus that a complex range of genetic, biological, psychological, and socio-environmental risk and maintenance factors contribute to the development and maintenance of AN. We consider how current interventions seek to tackle these factors in psychotherapy and potential limitations. Read More

Front Psychiatry 2019 4;10:102. Epub 2019 Mar 4.

Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.

Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those with EDs. Further, few studies have examined the cognitive-affective empathy profile in EDs. Read More

Eur Eat Disord Rev 2019 Mar 18. Epub 2019 Mar 18.

Faculty of Psychology and Educational Sciences, KU Leuven, Tiensestraat 102, 300 Leuven, Belgium.

The aim of this study was to examine the characteristics and content of intrusive images in patients with different subtypes of eating disorders (EDs). Data were collected from 74 ED patients, 22 dieting, and 29 nondieting controls. Participants completed a set of self-report questionnaires. Read More

Int J Eat Disord 2019 Mar 18. Epub 2019 Mar 18.

Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Objective: According to the ICD-10 and DSM-5, eating disorders (EDs) are classified using a categorical model that assumes the subtypes are qualitatively different from one another. However, it is still intensely debated that a dimensional model is more suitable. The aim of this study is to examine whether EDs have a categorical or dimensional latent structure using a sample of Chinese ED patients. Read More

Curr Opin Pediatr 2019 Mar 14. Epub 2019 Mar 14.

GMCCLINICS and Medical Department of the Eating Disorder Unit at The American Centre of Psychiatry and Neurology ACPN, Dubai, United Arab Emirates.

Purpose Of Review: The diagnosis of anorexia nervosa is associated with the highest mortality rate of any psychiatric disorder, mainly caused by medical complications.The purpose of this article is to review the common medical consequences of anorexia nervosa focusing on the special considerations related to children and adolescents and recent updates on the pathophysiology of these complications and their prognosis significance.

Recent Findings: The main findings were related to the diagnostic and prognostic value of hypokalaemia, QTc prolongation, hypoglycaemia and orthostatic changes. Read More

World J Biol Psychiatry 2019 Mar 18:1-26. Epub 2019 Mar 18.

e Department of Psychiatry , Psychiatric Genetics Unit, PUMS , Poznań , Poland.

Objectives: Opiorphin is a salivary peptide with analgesic and antidepressant properties. Its relationship with the hypothalamic-pituitary-adrenal, autonomic nervous and immune systems may provide understanding of chronic stress, especially in anorexia nervosa (AN). This study investigated a possible correlation between opiorphin and stress/immune biomarkers, respectively cortisol, alpha-amylase (sAA), secretory IgA (sIgA) in saliva of patients with restrictive-type of AN. Read More

BMJ Open 2019 Mar 15;9(3):e024913. Epub 2019 Mar 15.

Department of Clinical, Educational and Health Psychology, University College London, London, UK.

Introduction: Anorexia nervosa (AN) is an eating disorder characterised by restriction of energy intake, fears of gaining weight and related body image disturbances. The oxytocinergic system has been proposed as a pathophysiological candidate for AN. Oxytocin is a neuropeptide involved in bodily processes (eg, breast feeding) and in the onset of social behaviours (eg, bonding). Read More