161,143 results match your criteria Annual review of analytical chemistry Palo Alto Calif.[Journal]


Year effects: Inter-annual variation as a driver of community assembly dynamics.

Ecology 2020 May 26. Epub 2020 May 26.

Department of Plant Sciences, University of California, Davis, CA, 95616, USA.

Environmental conditions that vary from year-to-year can be strong drivers of ecological dynamics, including the composition of newly assembled communities. However, ecologists often chalk such dynamics up to "noise" in ecological experiments. Our lack of attention to such "year effects" hampers our understanding of contingencies in ecological assembly mechanisms and limits the generalizability of research findings. Read More

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http://dx.doi.org/10.1002/ecy.3104DOI Listing

Modeling Study of the Air Quality Impact of Record-Breaking Southern California Wildfires in December 2017.

J Geophys Res Atmos 2019 Jun 4;124(12):6554-6570. Epub 2019 Jun 4.

Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA.

We investigate the air quality impact of record-breaking wildfires in Southern California during 5-18 December 2017 using the Weather Research and Forecasting model with Chemistry in combination with satellite and surface observations. This wildfire event was driven by dry and strong offshore Santa Ana winds, which played a critical role in fire formation and air pollutant transport. By utilizing fire emissions derived from the high-resolution (375 × 375 m) Visible Infrared Imaging Radiometer Suite active fire detections, the simulated magnitude and temporal evolution of fine particulate matter (PM) concentrations agree reasonably well with surface observations (normalized mean bias = 4. Read More

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http://dx.doi.org/10.1029/2019jd030472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243153PMC

Direct Cost of Parkinson's Disease: A Real-World Data Study of Second-Line Therapies.

Parkinsons Dis 2020 12;2020:9106026. Epub 2020 May 12.

Deusto Business School Health, University of Deusto, Bilbao, Spain.

Parkinson's disease is one of the main reasons for neurological consultation in Spain. Due to the nature of the disease, it impacts patients, families, and caregivers. Parkinson's disease is a degenerative disease with no cure, although second-line therapies have recently improved the quality of life of patients in advanced stages. Read More

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http://dx.doi.org/10.1155/2020/9106026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240660PMC

Propranolol Is Associated with Lower Risk of Incidence of Hepatocellular Carcinoma in Patients with Alcoholic Cirrhosis: A Tertiary-Center Study and Indirect Comparison with Meta-Analysis.

Gastroenterol Res Pract 2020 9;2020:1892584. Epub 2020 Apr 9.

Faculty of Medicine, National Yang-Ming University, No. 155, Sec. 2, Linong Street, Beitou District, Taipei City 112, Taiwan.

Alcoholic cirrhosis (AC) leads to enormous disease burden and occupies a substantial proportion in the etiology of hepatocellular carcinoma (HCC), but scarce attention has been paid to this topic. Besides, propranolol has been reported to decrease the rate of HCC in viral hepatitis. We conducted a retrospective tertiary-center cohort study to identify the HCC incidence in AC patients with or without propranolol. Read More

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http://dx.doi.org/10.1155/2020/1892584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238337PMC

Regularization and error characterization of GRACE mascons.

J Geod 2019 Sep 15;93(9):1381-1398. Epub 2018 Apr 15.

NASA Goddard Space Flight Center, Greenbelt, MD, USA.

We present a new global time-variable gravity mascon solution derived from Gravity Recovery and Climate Experiment (GRACE) Level 1B data. The new product from the NASA Goddard Space Flight Center (GSFC) results from a novel approach that combines an iterative solution strategy with geographical binning of inter-satellite range-acceleration residuals in the construction of time-dependent regularization matrices applied in the inversion of mascon parameters. This estimation strategy is intentionally conservative as it seeks to maximize the role of the GRACE measurements on the final solution while minimizing the influence of the regularization design process. Read More

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http://dx.doi.org/10.1007/s00190-019-01252-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243853PMC
September 2019

Measuring individual external doses of Tokyo Electric Power Company Holdings employees living in Fukushima Prefecture.

J Radiol Prot 2020 May 26. Epub 2020 May 26.

Decontamination Promotion Office, Fukushima Revitalization Headquarters , Tokyo Electric Power Company Holdings Inc, Fukushima-city, Fukushima, 960-8041, JAPAN.

Since the accident at Fukushima Daiichi Nuclear Power Plant, individual external doses of residents have been investigated. To accurately analyze survey data, a variety of information, including the activity patterns of many residents, needs to be integrated. However, such large-scale surveys have not yet been conducted and actual individual external doses in Fukushima are unclear. Read More

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http://dx.doi.org/10.1088/1361-6498/ab968eDOI Listing

Cyclic volatile methylsiloxanes (cVMSs) in the air of the wastewater treatment plants in Dalian, China - Levels, emissions, and trends.

Chemosphere 2020 May 14;256:127064. Epub 2020 May 14.

China Academy of Transportation Sciences, Beijing, 100029, China.

Passive air samplers comprising sorbent-Tenax-TA thermal desorption tubes were applied for monitoring cyclic volatile methyl siloxanes (cVMSs) in the air above the aeration tanks of eight wastewater treatment plants (WWTPs, including five "open" and three "close" plants) in Dalian, China. The aim was to investigate the inputs of cVMSs from WWTPs to the air throughout a year (June 2016-July 2017). The ∑cVMS concentrations were averaged at 3. Read More

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http://dx.doi.org/10.1016/j.chemosphere.2020.127064DOI Listing

Genotyping and reassortment analysis of highly pathogenic avian influenza viruses H5N8 and H5N2 from Egypt reveals successive annual replacement of genotypes.

Infect Genet Evol 2020 May 23:104375. Epub 2020 May 23.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institute, Greifswald, Riems, Germany. Electronic address:

Highly pathogenic (HP) H5N1, clade 2.2.1, and low pathogenic avian influenza (LPAI) H9N2 viruses, G1-B lineage, are endemic in poultry in Egypt and have co-circulated for almost a decade. Read More

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http://dx.doi.org/10.1016/j.meegid.2020.104375DOI Listing
May 2020
3.015 Impact Factor

Epidemiology, Treatments, and Cardiac Complications in Patients with Kawasaki Disease: The Nationwide Survey in Japan, 2017-2018.

J Pediatr 2020 May 23. Epub 2020 May 23.

Division of Public Health, Center for Community Medicine, Jichi Medical University, Tochigi, Japan.

Objective: To report the epidemiologic characteristics, treatments, and cardiac complications of KD, using data from the nationwide survey in Japan.

Study Design: The nationwide KD survey in Japan has been conducted biennially since 1970. The most recent survey was completed in 2019, obtaining information for patients who developed KD during 2017-2018. Read More

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http://dx.doi.org/10.1016/j.jpeds.2020.05.034DOI Listing

A Tale of Good Fortune in the Era of DNA.

Authors:
Jeffrey Roberts

Annu Rev Microbiol 2020 May 26. Epub 2020 May 26.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA; email:

Two strains of good fortune in my career were to stumble upon the Watson-Gilbert laboratory at Harvard when I entered graduate school in 1964, and to study gene regulation in bacteriophage λ when I was there. λ was almost entirely a genetic item a few years before, awaiting biochemical incarnation. Throughout my career I was a relentless consumer of the work of previous and current generations of λ geneticists. Read More

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http://dx.doi.org/10.1146/annurev-micro-012520-073029DOI Listing

Post-Translation Regulation of Influenza Virus Replication.

Annu Rev Virol 2020 May 26. Epub 2020 May 26.

Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA; email:

Influenza virus exploits cellular factors to complete each step of viral replication. Yet, multiple host proteins actively block replication. Consequently, infection success depends on the relative speed and efficacy at which both the virus and host use their respective effectors. Read More

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http://dx.doi.org/10.1146/annurev-virology-010320-070410DOI Listing

Viral Hacks of the Plant Vasculature: The Role of Phloem Alterations in Systemic Virus Infection.

Annu Rev Virol 2020 May 26. Epub 2020 May 26.

Institute of Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland 20742, USA; email:

For plant viruses, the ability to load into the vascular phloem and spread systemically within a host is an essential step in establishing a successful infection. However, access to the vascular phloem is highly regulated, representing a significant obstacle to virus loading, movement, and subsequent unloading into distal uninfected tissues. Recent studies indicate that during virus infection, phloem tissues are a source of significant transcriptional and translational alterations, with the number of virus-induced differentially expressed genes being four- to sixfold greater in phloem tissues than in surrounding nonphloem tissues. Read More

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http://dx.doi.org/10.1146/annurev-virology-010320-072410DOI Listing

Exploring New Therapeutic Pathways in Pulmonary Hypertension: Metabolism, Proliferation, and Personalized Medicine.

Am J Respir Cell Mol Biol 2020 May 26. Epub 2020 May 26.

UCSF, 8785, Medicine , San Francisco, California, United States.

In this State-of-the-Field article, we explore the main themes from the 62nd Annual Aspen Lung Conference: hypoxia, cellular metabolism, inflammatory pathways, aberrant proliferation, and personalized medicine, and highlight challenges and opportunities in the coming decade of pulmonary vascular disease. Read More

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http://dx.doi.org/10.1165/rcmb.2020-0099TRDOI Listing

Pangenome Graphs.

Annu Rev Genomics Hum Genet 2020 May 26. Epub 2020 May 26.

Genomics Institute, University of California, Santa Cruz, California 95064, USA; email:

Low-cost whole-genome assembly has enabled the collection of haplotype-resolved pangenomes for numerous organisms. In turn, this technological change is encouraging the development of methods that can precisely address the sequence and variation described in large collections of related genomes. These approaches often use graphical models of the pangenome to support algorithms for sequence alignment, visualization, functional genomics, and association studies. Read More

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http://dx.doi.org/10.1146/annurev-genom-120219-080406DOI Listing

Treatment effect of posterior scleral reinforcement on controlling myopia progression: A systematic review and meta-analysis.

PLoS One 2020 26;15(5):e0233564. Epub 2020 May 26.

Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Background: High myopia is a sight-threatening disease that causes axial length elongation and severe complications. Data on the benefits of posterior scleral reinforcement surgery in myopia control have been conflicting. The purpose of this study was to explore the treatment effect and complications of posterior scleral reinforcement in the treatment of myopia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233564PLOS

Detection of Coxiella burnetii and equine herpesvirus 1, but not Leptospira spp. or Toxoplasma gondii, in cases of equine abortion in Australia - a 25 year retrospective study.

PLoS One 2020 26;15(5):e0233100. Epub 2020 May 26.

The Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia.

Equine abortion is a cause of severe economic loss to the equine industry. Equine herpesvirus 1 is considered a primary cause of infectious abortion in horses, however other infectious agents can also cause abortion. Abortions due to zoonotic pathogens have implications for both human and animal health. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233100PLOS

Influenzához kapcsolódó halálozás 2009/2010 és 2016/2017 között Magyarországon.

Orv Hetil 2020 Jun;161(23):962-970

Népességtudományi Kutatóintézet,Központi Statisztikai Hivatal Budapest, Buday László u. 1-3., 1024.

Introduction: In recent years, a significant mortality peak has been observed several times during the first months in Hungary. So far, no mortality study clarified the connection between the mortality peaks and influenza with results comparable with findings from other countries.

Aim: Calculation of the influenza-related number of death and excess mortality rates in Hungary for the period between 2009/10 and 2016/17, using the statistical package FluMONO. Read More

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http://dx.doi.org/10.1556/650.2020.31725DOI Listing

Evaluation of an Electronic Health Record System With a Disease Management Program and Health Care Treatment Costs for Danish Patients With Type 2 Diabetes.

JAMA Netw Open 2020 May 1;3(5):e206603. Epub 2020 May 1.

Danish Centre for Health Economics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

Importance: Electronic health record (EHR) systems and disease management programs (DMP) are often promoted, but associated health care cost changes are not well understood.

Objective: To evaluate the association between annual health care costs of patients with type 2 diabetes and the use of an electronic health record system with a disease management program (EHR/DMP) in general practice.

Design, Setting, And Participants: This retrospective cohort study examined patients with type 2 diabetes in Denmark between January 1, 2008, and December 31, 2014, who attended practices that either used an EHR/DMP at a high level or never used the disease management system. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.6603DOI Listing

Time Trends in the Diagnosis of Colorectal Cancer With Obstruction, Perforation, and Emergency Admission After the Introduction of Population-Based Organized Screening.

JAMA Netw Open 2020 May 1;3(5):e205741. Epub 2020 May 1.

Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba.

Importance: Up to 30% of patients with a diagnosis of colorectal cancer (CRC) present as an emergency (an intestinal obstruction, perforation, or emergency hospital admission) (OPE). There are limited data about the association of organized, population-based colorectal cancer screening with the rate of emergency presentations.

Objective: To examine the association of CRC screening with OPE at cancer diagnosis and time trends in the rate of OPE after the start of organized CRC screening using a highly sensitive fecal occult blood test. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.5741DOI Listing

Survival After Cancer Treatment at Top-Ranked US Cancer Hospitals vs Affiliates of Top-Ranked Cancer Hospitals.

JAMA Netw Open 2020 May 1;3(5):e203942. Epub 2020 May 1.

Abramson Cancer Center, University of Pennsylvania, Philadelphia.

Importance: Hospital networks formed around top-ranked cancer hospitals represent an opportunity to optimize complex cancer care in the community.

Objective: To compare the short- and long-term survival after complex cancer treatment at top-ranked cancer hospitals and the affiliates of top-ranked hospitals.

Design, Setting, And Participants: This cohort study was conducted using data from the unabridged version of the National Cancer Database. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.3942DOI Listing

Effects of a Workplace Wellness Program on Employee Health, Health Beliefs, and Medical Use: A Randomized Clinical Trial.

JAMA Intern Med 2020 May 26. Epub 2020 May 26.

Department of Finance, University of Illinois at Urbana-Champaign.

Importance: Many employers use workplace wellness programs to improve employee health and reduce medical costs, but randomized evaluations of their efficacy are rare.

Objective: To evaluate the effect of a comprehensive workplace wellness program on employee health, health beliefs, and medical use after 12 and 24 months.

Design, Setting, And Participants: This randomized clinical trial of 4834 employees of the University of Illinois at Urbana-Champaign was conducted from August 9, 2016, to April 26, 2018. Read More

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http://dx.doi.org/10.1001/jamainternmed.2020.1321DOI Listing

Healthcare Resource Utilization and Management of Chronic, Refractory Low Back Pain in the United States.

Spine (Phila Pa 1976) 2020 May 21. Epub 2020 May 21.

Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.

Study Design: Retrospective analysis of inpatient and outpatient medical insurance claims data from a database containing over 100 million individuals.

Objective: To quantify the healthcare resource utilization (HCRU) of non-surgical treatments in the first 2 years after a chronic, refractory low back pain (CRLBP) diagnosis.

Summary Of Background Data: Patients with persistent low back pain (LBP) despite conventional medical management and who are not candidates for spine surgery are considered to have chronic, refractory low back pain (CRLBP) and incur substantial healthcare costs over time. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003572DOI Listing

Intraoperative Detection of Hyperplastic Parathyroid Gland With Positron Emitter 18F-Fluorocholine and Handheld Probe.

Clin Nucl Med 2020 May 20. Epub 2020 May 20.

From the Departments of Nuclear Medicine and Radiation Protection.

We present the first intraoperative detection of a hyperplastic parathyroid gland with a positron emitter F-fluorocholine and handheld probe, with the estimation of the absorbed dose to the surgeon and surgical staff. Intraoperative positron emitter detection enabled the resection of a small parathyroid gland, resulting in normal postoperative values of PTH and serum calcium in a 69-year-old woman. Calculated whole-body dose to the surgical staff and surgeons' fingers is well below the annual limits for exposed workers and the general public. Read More

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http://dx.doi.org/10.1097/RLU.0000000000003106DOI Listing

Primary central nervous system lymphoma: status and advances in diagnosis, molecular pathogenesis, and treatment.

Chin Med J (Engl) 2020 May 21. Epub 2020 May 21.

Department of Hematology, Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Primary central nervous system lymphoma (PCNSL) is a rare group of extra-nodal non-Hodgkin lymphoma which is confined to the central nervous system or eyes. This article aims to present a brief profile of PCNSL diagnosis and treatment in immunocompetent patients. The authors retrieved information from the PubMed database up to September 2019. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000844DOI Listing

Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy.

Alzheimer Dis Assoc Disord 2020 May 22. Epub 2020 May 22.

Rush Alzheimer's Disease Center.

Purpose: Emerging evidence suggests that limbic-predominant age-related TAR DNA-binding protein-43 (TDP-43) encephalopathy impacts domain-specific literacy, a complex ability not assessed in traditional cognitive evaluations. We examined longitudinal profiles of financial and health literacy in relation to limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC).

Participants: A total of 275 community-dwelling older persons who had completed annual literacy assessments, died and undergone brain autopsy. Read More

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http://dx.doi.org/10.1097/WAD.0000000000000389DOI Listing

The Effect of Migration Duration on Treatment Delay Among Rural-to-Urban Migrants After the Integration of Urban and Rural Health Insurance in China: A Cross-Sectional Study.

Inquiry 2020 Jan-Dec;57:46958020919288

Prince of Songkla University, Hat Yai, Thailand.

Few researches have been focused on the treatment delay of rural-to-urban migrants in China. Our study aimed to investigate the effect of migration duration on treatment delay among rural-to-urban migrants in tertiary hospitals. A cross-sectional study was conducted based on a sample of 727 patients and surveyed factors including sociodemographics, medical costs, migration, treatment delay, and health cost-coping strategies. Read More

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http://dx.doi.org/10.1177/0046958020919288DOI Listing

Utilization Trends in Abdominal Imaging, 2004-2016.

AJR Am J Roentgenol 2020 May 26:1-5. Epub 2020 May 26.

Department of Radiology, Center for Research on Utilization of Imaging Services, Thomas Jefferson University Hospital, 132 S 10th St, Ste 780-A Main, Philadelphia, PA 19107.

The purpose of this study was to analyze recent trends in abdominal imaging utilization in the Medicare population. Medicare Part B databases for 2004-2016 were reviewed, and all Current Procedural Terminology codes pertaining to noninvasive imaging of the abdomen and pelvis were identified. Codes were grouped into six categories: CT and CT angiography (CTA), MRI and MR angiography (MRA), ultrasound, radionuclide imaging, radiography, and gastrointestinal fluoroscopy. Read More

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http://dx.doi.org/10.2214/AJR.19.22524DOI Listing

Associations between peer attachment and neural correlates of risk processing across adolescence.

Dev Cogn Neurosci 2020 Apr 14;42:100772. Epub 2020 Feb 14.

Department of Psychology, Virginia Tech, 233 Williams Hall, Blacksburg, VA, 24061, United States.

Adolescence is a period of increased risk-taking behavior where individual differences in risk taking may relate to both adverse and positive experiences with peers. Yet, knowledge on how risk processing develops in the adolescent brain and whether this development is related to peer attachment is limited. In this longitudinal functional magnetic resonance imaging (fMRI) study, we collected data from 167 adolescents (53% male) followed for four annual assessments across ages 13-17 years. Read More

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http://dx.doi.org/10.1016/j.dcn.2020.100772DOI Listing

Highlights of Research in Congenital Cardiac Anesthesia: Summary of Selected Abstracts From the 2020 Congenital Cardiac Anesthesia Society Annual Meeting.

Authors:
Gregory J Latham

Semin Cardiothorac Vasc Anesth 2020 May 26:1089253220924523. Epub 2020 May 26.

Seattle Children's Hospital, Seattle, WA, USA.

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http://dx.doi.org/10.1177/1089253220924523DOI Listing

Epidemiology of Pediatric Nonballistic Firearm Injuries to the Upper Extremity in the United States From 2000 to 2017.

Hand (N Y) 2020 May 26:1558944720926626. Epub 2020 May 26.

University of Pennsylvania, Philadelphia, USA.

This study aimed to describe the epidemiology of pediatric upper extremity injury secondary to nonballistic firearms in the United States. The National Electronic Injury Surveillance Survey (NEISS) database was queried between 2000 and 2017 for injuries to the upper extremity from nonballistic firearms in patients aged ≤18 years. In total, 1502 unique cases were identified. Read More

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http://dx.doi.org/10.1177/1558944720926626DOI Listing

Temporal association of sNfL and gad-enhancing lesions in multiple sclerosis.

Ann Clin Transl Neurol 2020 May 25. Epub 2020 May 25.

Harvard Medical School, Boston, Massachusetts, 02115, USA.

Objective: Multiple sclerosis (MS) is an autoimmune demyelinating disorder, which is characterized by relapses and remissions. Serum neurofilament light chain (sNfL) is an emerging biomarker of disease activity but its clinical use is still limited. In this study, we aim to characterize the temporal association between sNfL and new clinical relapses and new gadolinium-enhancing (Gd+) lesions. Read More

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http://dx.doi.org/10.1002/acn3.51060DOI Listing

Contemporary Survival Trends and etiological characterization in non-ischemic Dilated Cardiomyopathy.

Eur J Heart Fail 2020 May 25. Epub 2020 May 25.

Cardiovascular Department, Centre for Diagnosis and Management of Cardiomyopathies, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), University of Trieste, Italy.

Background: Contemporary survival trends of Dilated Cardiomyopathy (DCM) patients are largely unknown. The aims of this study are to describe clinical descriptors, survival trends and the prognostic impact of etiological characterization in DCM patients.

Methods: DCM patients were consecutively enrolled and divided into 4 groups according to the period of enrolment: 1 : 1978-1984; 2 : 1985-1994; 3 : 1995-2004; 4 : 2005-2015. Read More

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http://dx.doi.org/10.1002/ejhf.1914DOI Listing

Effect of alcohol prohibition on liver cirrhosis mortality rates in Canada from 1901 to 1956: A time-series analysis.

Drug Alcohol Rev 2020 May 25. Epub 2020 May 25.

Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.

Introduction And Aims: The extent to which alcohol consumption in Canada was affected by alcohol prohibition in the early 20th century remains unclear. Since there is a dearth of data on consumption during this time, we estimated the effect of alcohol prohibition on alcohol consumption, as measured by changes in liver cirrhosis mortality rates in Canada.

Design And Methods: Annual liver cirrhosis mortality data were obtained for 1901 to 1956 for the provinces of Alberta, British Columbia, Manitoba, New Brunswick, Nova Scotia, Ontario and Saskatchewan. Read More

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http://dx.doi.org/10.1111/dar.13089DOI Listing

Healthcare Resources Utilization and Costs of Patients with Non-IPF Progressive Fibrosing Interstitial Lung Disease Based on Insurance Claims in the USA.

Adv Ther 2020 May 21. Epub 2020 May 21.

Decision Resources Group, Burlington, USA.

Introduction: Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited.

Methods: We used USA-based medical insurance claims (2014-2016) to assess use and cost of healthcare resources in PF-ILD. Read More

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http://dx.doi.org/10.1007/s12325-020-01380-4DOI Listing

Revisiting the causal nexus between coal energy consumption, economic growth, and pollutant emission: sorting out the causality.

Environ Sci Pollut Res Int 2020 May 25. Epub 2020 May 25.

Faculty of Economics Administrative and Social sciences, Istanbul Gelisim University, Istanbul, Turkey.

Anthropogenic activities in search of livelihood come with its environmental implications. This is in line with the current crusade of the United Nations sustainable development goals (SDGs) target 7 and 13 for effective clean energy access and mitigating the adverse effect of climate change issues. Since the seminal study of Kraft and Kraft (1978) on the nexus between energy and gross national product, there has been no consensus in the extant literature in the last four decades. Read More

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http://dx.doi.org/10.1007/s11356-020-09265-3DOI Listing

The Clinical and Economic Burden of Newly Diagnosed Hereditary Transthyretin (ATTRv) Amyloidosis: A Retrospective Analysis of Claims Data.

Neurol Ther 2020 May 25. Epub 2020 May 25.

Akcea Therapeutics, Boston, MA, USA.

Introduction: Little is known about the burden of hereditary transthyretin (ATTRv) amyloidosis, a genetic, progressive, and fatal disease caused by extracellular deposition of transthyretin amyloid fibrils. The study's aim was to estimate costs and disease burden associated with ATTRv amyloidosis in a real-world setting.

Methods: Using IBM MarketScan Commercial and Medicare Supplemental data, we identified patients at least 18 years of age with newly diagnosed ATTRv amyloidosis. Read More

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http://dx.doi.org/10.1007/s40120-020-00194-4DOI Listing

Predictors of negotiated prices for new drugs in Germany.

Eur J Health Econ 2020 May 25. Epub 2020 May 25.

Institute for Health Services Research and Health Economics, Centre for Health and Society, Faculty of Medicine, Heinrich-Heine University Düsseldorf, Gebäude 12.49, Moorenstraße 5, 40225, Düsseldorf, Germany.

Introduction: In Germany, all new, innovative medicines are subject to an early benefit assessment by the German Federal Joint Committee with subsequent price negotiation and optional arbitration. The purpose of this study was to identify drivers of negotiated (including arbitrated) prices of new, non-orphan innovative medicines in Germany.

Methods: The analysis considered all non-orphan drugs that underwent a benefit appraisal between January 2011 and June 2016, and displayed a reimbursement price in the German Drug Directory (Lauer-Taxe) in November 2017. Read More

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http://dx.doi.org/10.1007/s10198-020-01201-zDOI Listing

Effects of long-term straw retention on soil microorganisms under a rice-wheat cropping system.

Arch Microbiol 2020 May 25. Epub 2020 May 25.

Industrial Crops Institute of Hubei Academy of Agricultural Sciences, No. 43, Nanhu Road, Hongshan District, Wuhan, Hubei Province, China.

The objective of this study was to investigate how straw-incorporating practices affect bacterial communities and carbon source utilization capacity under a rice-wheat rotational farming practice in central China. To clarify the effect of long-term straw incorporation in microbial abundance and carbon metabolism, a long-term field experiment was initiated in May 2005 (rice-planting season). Soil bacterial communities were revealed by high-throughput sequencing technology. Read More

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http://dx.doi.org/10.1007/s00203-020-01899-8DOI Listing

Choosing Primary Care: Factors Influencing Graduating Osteopathic Medical Students.

J Am Osteopath Assoc 2020 Jun;120(6):380-387

Context: Access to primary care (PC) improves health outcomes and decreases health care costs. The shortage of PC physicians and shifting physician workforce makes this an ongoing concern. Osteopathic medical schools are making strides to fill this void. Read More

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http://dx.doi.org/10.7556/jaoa.2020.060DOI Listing

Opioid prescribing patterns and usage after rhinologic surgery: A systematic review.

Am J Otolaryngol 2020 May 11:102539. Epub 2020 May 11.

Department of Otolaryngology - Head and Neck Surgery, New York Presbyterian Hospital - Weill Cornell Medicine, New York, NY, USA. Electronic address:

Objective: Judicious management of analgesics following rhinologic surgery is important for curtailing over-prescription of opioids. Limited data exists defining expected pain levels and appropriate opioid requirements after rhinologic surgery.

Methods: A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Read More

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http://dx.doi.org/10.1016/j.amjoto.2020.102539DOI Listing

Influence of fulfilment patient expectations in outcomes after total knee arthroplasty.

Rev Esp Cir Ortop Traumatol 2020 May 22. Epub 2020 May 22.

Área Docente de Bioestadística, Departamento de Matemáticas, Universidad de Castilla La Mancha, Ciudad Real, España.

Background And Objective: Compliance with preoperative expectations of patients undergoing total knee arthroplasty (TKA) is related to the degree of satisfaction, but its effect on other outcomes has not been studied. The aim of this study is to determine whether meeting expectations influences clinical, functional and quality of life outcomes at one year after surgery.

Material And Methods: The expectations of 183 patients were evaluated through the Hospital for Special Surgery Knee Replacement Expectations Survey. Read More

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http://dx.doi.org/10.1016/j.recot.2020.03.002DOI Listing

Access to allied health care services in Canadian interdisciplinary complex nerve injury programs.

Can J Neurol Sci 2020 May 26:1-12. Epub 2020 May 26.

British Columbia Centre for Complex Nerve Injury, Vancouver, British Columbia, Canada.

Nerve transfer surgery (NT) for patients with nerve and spinal cord injuries can result in dramatic functional improvements. As a result, interdisciplinary complex nerve injury programs (CNIPs) have been established in many Canadian centres, providing electrodiagnostic and surgical consultations in a single encounter. We sought to determine which allied health care services are included in Canadian CNIPs, at the 3rd Annual Canadian Peripheral Nerve Symposium. Read More

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http://dx.doi.org/10.1017/cjn.2020.98DOI Listing

The Prevalence and Incidence of Insomnia in Korea during 2005 to 2013.

Psychiatry Investig 2020 May 27. Epub 2020 May 27.

Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.

Objective: The aim of this study was to estimate the progress of insomnia prevalence and incidence over the past several years. Also, this study compared survival rates between individuals with and without insomnia.

Methods: The National Health Insurance Service-National Sample Cohort (NHIS-NSC) from 2002-2013 was used for this study. Read More

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http://dx.doi.org/10.30773/pi.2019.0218DOI Listing

Parkinson's disease polygenic risk score is not associated with impulse control disorders: A longitudinal study.

Parkinsonism Relat Disord 2020 May 1;75:30-33. Epub 2020 May 1.

CHU, Toulouse, France.

Objective: To examine the relationship between a Parkinson's disease (PD) polygenic risk score (PRS) and impulse control disorders (ICDs) in PD.

Background: Genome wide association studies (GWAS) have brought forth a PRS associated with increased risk of PD and younger disease onset. ICDs are frequent adverse effects of dopaminergic drugs and are also more frequent in patients with younger disease onset. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2020.03.017DOI Listing

Prenatal maternal stress and child hair cortisol Four years later: Evidence from a low-income sample.

Psychoneuroendocrinology 2020 May 17;117:104707. Epub 2020 May 17.

University of California, Los Angeles, United States. Electronic address:

Background: Maternal stress during pregnancy can influence the trajectory of fetal development, shaping offspring physiology and health in enduring ways. Some research implicates fetal programming of the hypothalamic-pituitary-adrenocortical (HPA) axis as a mediator of these effects. The present study is the first to examine child hair cortisol concentration (HCC) and maternal stress during pregnancy in a diverse, low-income sample. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2020.104707DOI Listing

Eight years of variations in ecosystem respiration over a residue-incorporated rotation cropland and its controlling factors.

Sci Total Environ 2020 May 11;733:139325. Epub 2020 May 11.

Agricultural Collage, Shenyang Agricultural University, Shenyang, China.

The carbon dioxide emissions from cropland play important roles in the regional carbon budget. In this study, continuous measurements of the ecosystem respiration (RE) were obtained using the eddy covariance technique in a winter wheat-summer maize double cropping agroecosystem mainly between 2004 and 2012 in order to identify the among-year variations in RE and the related factors responsible. The annual RE, estimated by Lloyd and Taylor model, which was the most accurate, was 1866. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139325DOI Listing

Assessment of the main factors affecting the dynamics of nutrients in two rainfed cereal watersheds.

Sci Total Environ 2020 May 5;733:139177. Epub 2020 May 5.

Department of Rural Development, Environment and Local Administration, Government of Navarre, C/ González Tablas 9, 31003 Pamplona, Navarra, Spain.

Nutrient dynamics and factors that control nutrient exports were observed in two watersheds, namely Latxaga and La Tejería, with similar climatic and management characteristics throughout 10 years (2007-2016). Similar patterns were observed in intra-annual and inter-annual dynamics with higher NO concentration and NO-N yield during the humid seasons (i.e. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139177DOI Listing

The 12-year trend report of antipsychotic usage in a nationwide claims database derived from four million people in Japan.

J Psychiatr Res 2020 May 13;127:28-34. Epub 2020 May 13.

Department of Pharmacy, Osaka Medical College Hospital, 2-7 Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.

The current study aimed to describe the use of antipsychotics to clarify the gap between clinical guidelines and health care practice in Japan. We used data from the JMDC Claims Database (JMDC Inc., Tokyo, Japan), a nationwide claims database, from 2005 to 2016. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2020.05.012DOI Listing

Risk factors associated with severe perineal tears: a five-year study.

J Gynecol Obstet Hum Reprod 2020 May 22:101820. Epub 2020 May 22.

Centre d'Études Périnatales de l'Océan Indien (CEPOI) - EA7388, Centre Hospitalier Universitaire de la Réunion, Saint-Pierre Cedex, La Réunion, France; Réanimation Néonatale et Pédiatrique, Néonatologie, Centre Hospitalier Universitaire Sud Réunion, Saint-Pierre Cedex, La Réunion, France.

Objective: Our aim was to describe risk factors associated with 34DPT in operative and non-operative vaginal deliveries, over a five-year period.

Study Design: This was a retrospective cohort study including 39,227 vaginal deliveries from 2013 to 2017 in a single French University Hospital. Annual characteristics of the analyzed population were recorded. Read More

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http://dx.doi.org/10.1016/j.jogoh.2020.101820DOI Listing

Role of Non-Coding RNAs as Novel Biomarkers for Detection of Colorectal Cancer Progression through Interaction with the Cell Signaling Pathways.

Gene 2020 May 22:144796. Epub 2020 May 22.

Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran; Department of Cellular Biotechnology, Cell Science research Centre, Royan Institute for Biotechnology, ACECR, Isfahan, Iran; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), University of Pablo de Olavide-University of Seville-CSIC, Sevilla, Spain. Electronic address:

Colorectal cancer (CRC) is one of the most common types of cancer which affects the colon and the rectum. Approximately one third of annual CRC mortality occurs due to the late detection of this type of cancer. Therefore, there is an urgent need for more powerful diagnostic and prognostic tools for identification and treatment of colorectal tumorigenesis. Read More

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http://dx.doi.org/10.1016/j.gene.2020.144796DOI Listing