Annu Rev Mater Res 2015 Jul 23;45:277-310. Epub 2015 Mar 23.
Biomedical Engineering Department, Northwestern University, Evanston, Illinois 60208; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208; Simpson Querrey Institute for Bionanotechnology, Northwestern University, Chicago, Illinois 60611.
Advances in biomaterials science and engineering are crucial to translating regenerative engineering, an emerging field that aims to recreate complex tissues, into clinical practice. In this regard, citrate-based biomaterials have become an important tool owing to their versatile material and biological characteristics including unique antioxidant, antimicrobial, adhesive, and fluorescent properties. This review discusses fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering. Read More