148,963 results match your criteria Annual Reports in Pharmacopsychiatric Research[Journal]


Single Low-Volume Center Experience with Frozen Elephant Trunk in Acute Type A Aortic Dissections.

Aorta (Stamford) 2018 Dec 24;6(6):125-129. Epub 2019 Apr 24.

Department of Cardiac Surgery, Virgen de la Salud Hospital, Toledo, Spain.

Background:  Acute Type A aortic dissection (AAAD) is a surgical emergency. In patients with arch and descending aorta involvement (DeBakey Type I), a total aortic arch replacement with frozen elephant trunk (FET) could favor false lumen thrombosis and improve long-term results. The authors hereby present their experience with this technique in a single low-volume center, to assess whether the technique is feasible to treat such disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0039-1677809DOI Listing
December 2018

Small-Molecule-Based Fluorescent Sensors for Selective Detection of Reactive Oxygen Species in Biological Systems.

Annu Rev Biochem 2019 Apr 24. Epub 2019 Apr 24.

Morningside Laboratory for Chemical Biology, Department of Chemistry, The University of Hong Kong, Hong Kong, P. R. China; email: , , , ,

Reactive oxygen species (ROS) encompass a collection of intricately linked chemical entities characterized by individually distinct physicochemical properties and biological reactivities. Although excessive ROS generation is well known to underpin disease development, it has become increasingly evident that ROS also play central roles in redox regulation and normal physiology. A major challenge in uncovering the relevant biological mechanisms and deconvoluting the apparently paradoxical roles of distinct ROS in human health and disease lies in the selective and sensitive detection of these transient species in the complex biological milieu. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-biochem-013118-111754DOI Listing

Gene and Induced Pluripotent Stem Cell Therapy for Retinal Diseases.

Annu Rev Genomics Hum Genet 2019 Apr 24. Epub 2019 Apr 24.

Laboratory for Retinal Regeneration, Center for Biosystems Dynamics Research, RIKEN, Kobe, Hyogo 650-0047, Japan; email:

Given the importance of visual information to many daily activities, retinal degenerative diseases-which include both inherited conditions (such as retinitis pigmentosa) and acquired conditions (such as age-related macular degeneration)-can have a dramatic impact on human lives. The therapeutic options for these diseases remain limited. Since the discovery of the first causal gene for retinitis pigmentosa almost three decades ago, more than 250 genes have been identified, and gene therapies have been rapidly developed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-genom-083118-015043DOI Listing

Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex.

Annu Rev Genomics Hum Genet 2019 Apr 24. Epub 2019 Apr 24.

F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA; email:

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects multiple organ systems due to an inactivating variant in either or , resulting in the hyperactivation of the mechanistic target of rapamycin (mTOR) pathway. Dysregulated mTOR signaling results in increased cell growth and proliferation. Clinically, TSC patients exhibit great phenotypic variability, but the neurologic and neuropsychiatric manifestations of the disease have the greatest morbidity and mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-genom-083118-015354DOI Listing

The Genetics and Epigenetics of Facioscapulohumeral Muscular Dystrophy.

Annu Rev Genomics Hum Genet 2019 Apr 24. Epub 2019 Apr 24.

Department of Pharmacology, School of Medicine, University of Nevada, Reno, Nevada 89557, USA; email:

Facioscapulohumeral muscular dystrophy (FSHD), a progressive myopathy that afflicts individuals of all ages, provides a powerful model of the complex interplay between genetic and epigenetic mechanisms of chromatin regulation. FSHD is caused by dysregulation of a macrosatellite repeat, either by contraction of the repeat or by mutations in silencing proteins. Both cases lead to chromatin relaxation and, in the context of a permissive allele, aberrant expression of the gene in skeletal muscle. Read More

View Article

Download full-text PDF

Source
https://www.annualreviews.org/doi/10.1146/annurev-genom-0831
Publisher Site
http://dx.doi.org/10.1146/annurev-genom-083118-014933DOI Listing
April 2019
1 Read

Bile Acids as Metabolic Regulators and Nutrient Sensors.

Annu Rev Nutr 2019 Apr 24. Epub 2019 Apr 24.

Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, Ohio 44272; email:

Bile acids facilitate nutrient absorption and are endogenous ligands for nuclear receptors that regulate lipid and energy metabolism. The brain-gut-liver axis plays an essential role in maintaining overall glucose, bile, and immune homeostasis. Fasting and feeding transitions alter nutrient content in the gut, which influences bile acid composition and pool size. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-nutr-082018-124344DOI Listing

Single Nanoparticle Electrochemistry.

Annu Rev Anal Chem (Palo Alto Calif) 2019 Apr 24. Epub 2019 Apr 24.

School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China; email: ;

Experimental techniques to monitor and visualize the behaviors of single nanoparticles have not only revealed the significant spatial and temporal heterogeneity of those individuals, which are hidden in ensemble methods, but more importantly, they have also enabled researchers to elucidate the origin of such heterogeneity. In pursuing the intrinsic structure-function relations of single nanoparticles, the recently developed stochastic collision approach demonstrated some early promises. However, it was later realized that the appropriate sizing of a single nanoparticle by an electrochemical method could be far more challenging than initially expected owing to the dynamic motion of nanoparticles in electrolytes and complex charge-transfer characteristics at electrode surfaces. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-anchem-061318-114902DOI Listing

Early Binaural Hearing: The Comparison of Temporal Differences at the Two Ears.

Annu Rev Neurosci 2019 Apr 24. Epub 2019 Apr 24.

Department of Neuroscience, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands.

Many mammals, including humans, are exquisitely sensitive to tiny time differences between sounds at the two ears. These interaural time differences are an important source of information for sound detection, for sound localization in space, and for environmental awareness. Two brainstem circuits are involved in the initial temporal comparisons between the ears, centered on the medial and lateral superior olive. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-neuro-080317-061925DOI Listing

What, If, and When to Move: Basal Ganglia Circuits and Self-Paced Action Initiation.

Annu Rev Neurosci 2019 Apr 24. Epub 2019 Apr 24.

Champalimaud Research, Champalimaud Centre for the Unknown, 1400-038 Lisbon, Portugal.

Deciding what to do and when to move is vital to our survival. Clinical and fundamental studies have identified basal ganglia circuits as critical for this process. The main input nucleus of the basal ganglia, the striatum, receives inputs from frontal, sensory, and motor cortices and interconnected thalamic areas that provide information about potential goals, context, and actions and directly or indirectly modulates basal ganglia outputs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-neuro-072116-031033DOI Listing

Advances in the Use of Microfluidics to Study Crystallization Fundamentals.

Annu Rev Chem Biomol Eng 2019 Apr 24. Epub 2019 Apr 24.

Aix-Marseille Université, CNRS, CINaM UMR 7325, 13288 Marseille, France; email: , , ,

This review compares droplet-based microfluidic systems used to study crystallization fundamentals in chemistry and biology. An original high-throughput droplet-based microfluidic platform is presented. It uses nanoliter droplets, generates a chemical library, and directly solubilizes powder, thus economizing both material and time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-chembioeng-060718-030312DOI Listing

Shrubs indirectly increase desert seedbanks through facilitation of the plant community.

PLoS One 2019 24;14(4):e0215988. Epub 2019 Apr 24.

Department of Biology, York University, Toronto, Ontario, Canada.

The mechanisms supporting positive ecological interactions are important. Foundation species can structure desert biodiversity by facilitating seedbanks of annual plants, but the direct and indirect mechanisms of shrub effects on seedbank have not been experimentally decoupled. We conducted the first test of shrubs increasing seedbank densities through direct effects on the seedbank (i. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215988PLOS

Densities and drivers of sea turtle populations across Pacific coral reef ecosystems.

PLoS One 2019 24;14(4):e0214972. Epub 2019 Apr 24.

Monterey Bay Aquarium, Monterey, California, United States of America.

Sea turtle populations are often assessed at the regional to sub-basin scale from discrete indices of nesting abundance. While this may be practical and sometimes effective, widespread in-water surveys may enhance assessments by including additional demographics, locations, and revealing emerging population trends. Here, we describe sea turtle observations from 13 years of towed-diver surveys across 53 coral islands, atolls, and reefs in the Central, West, and South Pacific. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214972PLOS

Long-term fish assemblages of the Ohio River: Altered trophic and life history strategies with hydrologic alterations and land use modifications.

PLoS One 2019 24;14(4):e0211848. Epub 2019 Apr 24.

Department of Biology, Ball State University, Muncie, Indiana, United States of America.

Long-term monitoring of species assemblages provides a unique opportunity to test hypotheses regarding environmentally induced directional trajectories of freshwater species assemblages. We used 57 years of lockchamber fish rotenone and boat electrofishing survey data (1957-2014) collected by the Ohio River Valley Water Sanitation Commission (ORSANCO) to test for directional trajectories in taxonomy, trophic classifications, and life history strategies of freshwater fish assemblages in the Ohio River Basin. We found significant changes in taxonomic and trophic composition of freshwater fishes in the Ohio River Basin. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211848PLOS

Socio- and Clinical Characteristics in Relation to Mammography Screening Compliance.

Authors:
Sue M Lai Can Meng

J Registry Manag 2018 ;45(1):136-142

Use of mammography screening in the general population has been credited with improvements in the diagnosis of breast cancer. Yet, the proportion of women with invasive breast cancers who are diagnosed at later, distant stages has not been declining. Two statewide data sources were linked to compare mammography screening compliance of female Medicare beneficiaries and stage of breast cancer at diagnosis at a population level. Read More

View Article

Download full-text PDF

Source
January 2018

The Austrian UVA-Network.

Photochem Photobiol 2019 Apr 24. Epub 2019 Apr 24.

Medical University Innsbruck, Div. of Biomedical Physics, Austria.

The ultraviolet-A (UVA) part of the solar spectrum at the Earth's surface is an essential environmental factor but continuous long-time monitoring of UVA radiation is rarely done. In Austria, three existing stations of the UV monitoring network have been upgraded with UVA broadband instruments. At each station, one instrument measures global UVA irradiance and - in parallel - a second instrument measures diffuse irradiance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/php.13111DOI Listing

Changes in Microbial Profiles and Antibiotic Resistance Patterns in Patients with Biliary Tract Infection Over a Six-Year Period.

Surg Infect (Larchmt) 2019 Apr 24. Epub 2019 Apr 24.

3 Department of Laboratory Medicine, School of Medicine of Shaoxing University, Shaoxing, Zhejiang, China.

Biliary tract infection (BTI) is a common complication in patients with biliary obstruction caused by various biliary tract disorders. To improve the management of patients with BTI, microbial profiles from bile cultures and antibiotic resistance patterns were evaluated in this six-year retrospective study. A total of 709 patients with various biliary tract disorders from January 2012 to December 2017 were enrolled in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/sur.2019.041DOI Listing

Cortisol awakening response and additive serotonergic genetic risk interactively predict depression in two samples: The 2019 Donald F. Klein Early Career Investigator Award Paper.

Depress Anxiety 2019 Apr 24. Epub 2019 Apr 24.

Human Development and Social Policy Program, School of Education & Social Policy and Cells to Society Center, Institute for Policy Research, Northwestern University, Evanston, Illinois.

Background: The serotonin system and hypothalamic pituitary-adrenal (HPA)-axis are each implicated in the pathway to depression; human and animal research support these systems' cross-talk. Our work implicates a 5-variant additive serotoninergic multilocus genetic profile score (MGPS) and separately the cortisol awakening response (CAR) in the prospective prediction of depression; other work has shown that the serotonin transporter polymorphism 5HTTLPR predicts CAR and interacts with the CAR to predict depression.

Methods: We tested the hypothesis that a 6-variant MGPS (original plus 5HTTLPR) would interact with CAR to predict prospective depressive episode onsets in 201 emerging adults using four annual follow-up interviews. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/da.22899DOI Listing

Budget Impact Analysis of Cancer Screening: A Methodological Review.

Appl Health Econ Health Policy 2019 Apr 24. Epub 2019 Apr 24.

Department of Public Health, Health Services Research and Health Technology Assessment, Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT-University for Health Sciences, Medical Informatics and Technology, Eduard-Wallnoefer-Zentrum 1, 6060, Hall in Tyrol, Austria.

Background: Budget impact analyses (BIAs) describe changes in intervention- and disease-related costs of new technologies. Evidence on the quality of BIAs for cancer screening is lacking.

Objectives: We systematically reviewed the literature and methods to assess how closely BIA guidelines are followed when BIAs are performed for cancer-screening programs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40258-019-00475-6DOI Listing

Longitudinal Quantitation of Tooth Displacement in Chinese Adolescents with Normal Occlusion.

Curr Med Sci 2019 Apr 23;39(2):317-324. Epub 2019 Apr 23.

Department of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China.

This longitudinal study aims to analyze the different modes of the maxillary and mandibular tooth displacement in subjects, who were aged 12.5-17.5 years (150-210 months), with untreated normal (Class I) occlusion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11596-019-2037-zDOI Listing

Prenatal maternal personality as an early predictor of vulnerable parenting style.

Arch Womens Ment Health 2019 Apr 23. Epub 2019 Apr 23.

Institute for Social Science Research, The University of Queensland, Brisbane, Australia.

Perinatal mental health problems, particularly depression, are prevalent and have been a central focus of prevention initiatives. The greater proportion of ongoing annual perinatal mental health economic cost burdens relate to children. A key linking mechanism is mother-infant relationship quality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00737-019-00963-7DOI Listing

[The geriatric syndrome of anemia-Summary of the symposium of the working group anemia during the annual meeting of the German Geriatric Society 2018 in Cologne, Germany].

Z Gerontol Geriatr 2019 Apr 23. Epub 2019 Apr 23.

Klinik für Geriatrie, Alexianer Krefeld GmbH, Krefeld, Deutschland.

This year's symposium of the working group anemia of the German Geriatric Society (DGG) aimed to underline the multicausality of anemia in the aged and to highlight definition parallels with geriatric syndromes. For these reasons, nutritional and malignant causes for anemia were discussed and the influence of oxidative stress on the development of anemia was underlined. The need for ongoing research in the field of anemia in the aged was emphasized by the lack of perioperative transfusion strategies in geriatric patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00391-019-01545-zDOI Listing

Priorities for protecting health from climate change in the WHO European Region: recent regional activities.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 Apr 18. Epub 2019 Apr 18.

World Health Organization Regional Office for Europe, European Centre for Environment and Health, Platz der Vereinigten Nationen 1, 53113, Bonn, Germany.

Evidence of the impact of climate change on health is growing. Health systems need to be prepared and gradually adapt to the effects of climate change, including extreme weather events.Fossil fuel combustion as the driver of climate change poses a tremendous burden of disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00103-019-02943-9DOI Listing

Divergent geography of Wangata and Typhimurium epidemiology in New South Wales, Australia.

One Health 2019 Jun 9;7:100092. Epub 2019 Apr 9.

Marie Bashir Institute for Infectious Diseases and Biosecurity, Westmead Institute for Medical Research, The University of Sydney, Westmead, New South Wales, Australia.

serovar Wangata is an important cause of salmonellosis in the state of New South Wales, Australia. Standard surveillance has not identified a common food source and cases have been attributed to an unknown environmental or wildlife reservoir. Investigation of the spatial distribution of cases may provide valuable insights into local risk factors for infection and the potential role of the environment and wildlife. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.onehlt.2019.100092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475636PMC

Economic valuation from direct use of mangrove forest restoration in Balikpapan Bay, East Kalimantan, Indonesia.

F1000Res 2019 3;8. Epub 2019 Jan 3.

Faculty of Forestry, Mulawarman University, Samarinda, East Kalimantan, 75117, Indonesia.

The mangrove forests in Balikpapan Bay, Indonesia, have been used as a source of livelihood for local community more than 150 years. Since the natural products of the mangrove forest, such as wood and seafood, are not able to meet the economic needs of the local community, some areas have been converted into brackish water ponds with traditional aquaculture systems. The growth of brackish water ponds over the last five decades has been identified as the main cause of ecosystem destruction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/f1000research.17012.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456837PMC
January 2019

Decline in abundance and apparent survival rates of fin whales () in the northern Gulf of St. Lawrence.

Ecol Evol 2019 Apr 15;9(7):4231-4244. Epub 2019 Mar 15.

Sea Mammal Research Unit, Scottish Oceans Institute University of St Andrews Fife UK.

Estimates of abundance and survivorship provide quantifiable measures to monitor populations and to define and understand their conservation status. This study investigated changes in abundance and survival rates of fin whales () in the northern Gulf of St. Lawrence in the context of anthropogenic pressures and changing environmental conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ece3.5055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468087PMC

Numbers and distribution of the Great Cormorant in Iceland: Limitation at the regional and metapopulation level.

Ecol Evol 2019 Apr 12;9(7):3984-4000. Epub 2019 Mar 12.

Research Centre at Snæfellsnes University of Iceland Stykkishólmur Iceland.

We studied a metapopulation of great cormorant in Iceland, using complete aerial censuses of nests in 25 years during 1975-2015. Age composition was estimated in 1998-2014 by ground surveys in September and February. Brood size was estimated from aerial photographs in 2007-2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ece3.5028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468091PMC

The latitudinal herbivory hypothesis revisited: To be part is to be whole.

Ecol Evol 2019 Apr 19;9(7):3681-3688. Epub 2019 Mar 19.

Coastal Ecosystems Research Station of the Yangtze River Estuary Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering Institute of Biodiversity Science Fudan University Shanghai China.

As the big data accumulation in ecology picks up pace, we now have the opportunity to test several macroecological hypotheses, such as the latitudinal herbivory hypothesis (LHH) dated from the 1990s. The LHH proposes that plant-herbivore interactions decrease as latitude increases, that is, from lower latitudinal areas (i.e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ece3.2759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467846PMC

Vaccine safety surveillance in Canada: Reports to CAEFISS, 2013-2016.

Can Commun Dis Rep 2018 Sep 6;44(9):206-214. Epub 2018 Sep 6.

CAEFISS: Canadian Adverse Events Following Immunization Surveillance System, Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.

Background: Canada has one of the strongest vaccine safety surveillance systems in the world. This system includes both passive surveillance of all vaccines administered and active surveillance of all childhood vaccines.

Objectives: To provide 1) a descriptive analysis of the adverse events following immunization (AEFI) reports for vaccines administered in Canada, 2) an analysis of serious adverse events (SAEs) and 3) a list of the top ten groups of vaccines with the highest reporting rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14745/ccdr.v44i09a04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449118PMC
September 2018

Summary of the NACI Seasonal Influenza Vaccine Statement for 2018-2019.

Can Commun Dis Rep 2018 Jun 7;44(6):123-128. Epub 2018 Jun 7.

Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.

Background: There are many different influenza vaccines authorized for use in Canada and new evidence on influenza and vaccines is emerging all the time. The National Advisory Committee on Immunization (NACI) provides recommendations annually regarding seasonal influenza vaccines to the Public Health Agency of Canada (PHAC).

Objective: To summarize the NACI recommendations regarding the use of seasonal influenza vaccines for the 2018-2019 influenza season in light of two NACI reviews conducted on 1) the risk of serious influenza-related complications in children and adults with neurologic and neurodevelopment conditions and 2) the efficacy/effectiveness of high-dose and adjuvanted inactivated influenza vaccines in persons 65 years of age and older. Read More

View Article

Download full-text PDF

Source

West Nile virus illness in Ontario, Canada: 2017.

Can Commun Dis Rep 2019 Jan 3;44(1):32-37. Epub 2019 Jan 3.

Enteric, Zoonotic and Vector-borne Diseases, Communicable Diseases and Emergency Preparedness and Response, Public Health Ontario, Toronto, ON.

Background: In Canada, the annual incidence rates of West Nile virus (WNV) illness have fluctuated over the last 15 years. Ontario is one of the provinces in Canada most affected by WNV and, as a result, has implemented robust mosquito and human surveillance programs.

Objective: To summarize and discuss the epidemiology of WNV illness in Ontario, Canada in 2017, with comparisons to previous years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14745/ccdr.v45i01a04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461128PMC
January 2019

Evaluation of a commercial liquid-chromatography high-resolution mass-spectrometry method for the determination of hepcidin-25.

Biochem Med (Zagreb) 2019 Jun 15;29(2):020701. Epub 2019 Apr 15.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.

Introduction: Reliable determination of hepcidin-25, a key regulator of iron metabolism, is important. This study aimed at evaluating the performance of the Hepcidin-25 Liquid Chromatography-Tandem Mass-Spectrometry (LC-MS/MS) Kit (Immundiagnostik AG, Bensheim, Germany) for quantification of the hepcidin-25 protein.

Materials And Methods: Precision, accuracy, linearity, and preanalytical requirements of the liquid-chromatography high-resolution mass-spectrometry (LC-HR-MS) method were evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11613/BM.2019.020701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457918PMC

Measured Canadian oil sands CO emissions are higher than estimates made using internationally recommended methods.

Nat Commun 2019 Apr 23;10(1):1863. Epub 2019 Apr 23.

Climate Research Division, Environment and Climate Change Canada, 4905 Dufferin Street, Toronto, ON, M3H 5T4, Canada.

The oil and gas (O&G) sector represents a large source of greenhouse gas (GHG) emissions globally. However, estimates of O&G emissions rely upon bottom-up approaches, and are rarely evaluated through atmospheric measurements. Here, we use aircraft measurements over the Canadian oil sands (OS) to derive the first top-down, measurement-based determination of the their annual CO emissions and intensities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09714-9DOI Listing
April 2019
2 Reads

Disease burden of liver cancer in China from 1997 to 2016: an observational study based on the Global Burden of Diseases.

BMJ Open 2019 Apr 23;9(4):e025613. Epub 2019 Apr 23.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Objective: To evaluate the trends in disease burden and the epidemiological features of liver cancer in China while identifying potential strategies to lower the disease burden.

Design: Observational study based on the Global Burden of Diseases.

Participants: Data were publicly available and de-identified and individuals were not involved. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-025613DOI Listing

Trends in occupational diseases in Finland, 1975-2013: a register study.

BMJ Open 2019 Apr 23;9(4):e024040. Epub 2019 Apr 23.

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Objectives: The objective was to investigate trends in the incidence of recognized and suspected cases of occupational diseases in Finland from 1975 to 2013, including variations by industry - and describe and recognize factors affecting variations in incidence.

Design: A register study.

Setting: The data consisted of recognized and suspected cases of occupational diseases recorded in the Finnish Registry of Occupational Diseases (FROD) in 1975-2013. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-024040DOI Listing

Phenotypic and molecular traits determine the tolerance of olive trees to drought stress.

Plant Physiol Biochem 2019 Apr 16;139:521-527. Epub 2019 Apr 16.

Department of Soil Microbiology and Symbiotic Systems, Estación Experimental del Zaidín (CSIC), C/Profesor Albareda 1, 18008, Granada, Spain.

Olive trees are known for their capacity to adapt to drought through several phenotypic and molecular variations, although this can vary according to the different provenances of the same olive cultivar. We confronted the same olive cultivar from two different location in Spain: Freila, in the Granada province, with low annual precipitation, and Grazalema, in the Cadiz province, with high annual precipitation, and subjected them to five weeks of severe drought stress. We found distinctive physiological and developmental adaptations among the two provenances. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plaphy.2019.04.017DOI Listing

En Face Imaging of Geographic Atrophy Using Different Swept-Source OCT Scan Patterns.

Ophthalmol Retina 2019 Feb 14;3(2):122-132. Epub 2018 Sep 14.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address:

Purpose: Different swept-source (SS) OCT scan patterns were used to image geographic atrophy (GA) to determine if they provided similar area and enlargement measurements in eyes with age-related macular degeneration (AMD).

Design: Prospective, observational case series.

Participants: Patients with GA secondary to nonexudative AMD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oret.2018.09.004DOI Listing
February 2019

Characteristics of apparently healthy individuals with a very low C-reactive protein.

Clin Chim Acta 2019 Apr 20. Epub 2019 Apr 20.

Department of Internal Medicine "C", "D" and "E", Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 6423906, Israel.

Background: The importance of the inflammatory processes and C-reactive protein (CRP) evaluation was observed. Only few studies used cut-off value <1 mg/L. We sought to evaluate the association between very low CRP (vlCRP) and health status, to describe the repetition of vlCRP and to identify predictors for repetition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cca.2019.04.073DOI Listing

Functional deficits and other psychiatric associations with abnormal scores on the Montreal Cognitive Assessment (MoCA) in older HIV-infected patients.

Int Psychogeriatr 2019 Apr 24:1-14. Epub 2019 Apr 24.

Department of Clinical Pharmacy,University of California San Francisco,San Francisco, CA,USA.

ABSTRACTObjective:The authors assessed the association of physical function, social variables, functional status, and psychiatric co-morbidity with cognitive function among older HIV-infected adults.

Design: From 2012-2014, a cross-sectional study was conducted among HIV-infected patients ages 50 or older who underwent comprehensive clinical geriatric assessment.

Setting: Two San Francisco HIV clinics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610219000413DOI Listing

Equine Welfare in Practice: A Collaborative Outreach and Education Program with Michigan State University, Universidad Nacional Autónoma de México, and Universidad Veracruzana.

Animals (Basel) 2019 Apr 13;9(4). Epub 2019 Apr 13.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad Universitaria, D.F. México C.P. 04501, Mexico.

There is great need for veterinary care for working equids worldwide. Addressing this need provides an opportunity for veterinary students to gain primary care experience. An annual two week collaborative outreach and educational program with Michigan State University (MSU), the Universidad Nacional Autónoma de México (UNAM) and the Universidad Veracruzana (UV) was developed to provide care for working equids in rural Mexican communities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ani9040164DOI Listing

Utilization and Safety of Percutaneous Lung Biopsy: A 10-Year Nationwide Population-Based Study.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

Institute of Hospital and Health Care Administration, School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan.

Percutaneous lung biopsy is a technique used for sampling peripherally located lung masses and has been gaining in popularity. However, its exact utilization is unknown, and its safety has not been well studied. The current study aimed to assess the trend of utilization and study the safety of this procedure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16081316DOI Listing

Genetic Mapping and Molecular Characterization of a Broad-spectrum Resistance Gene in Chinese Soybean.

Int J Mol Sci 2019 Apr 12;20(8). Epub 2019 Apr 12.

National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Phytophthora root rot (PRR) causes serious annual soybean yield losses worldwide. The most effective method to prevent PRR involves growing cultivars that possess genes conferring resistance to Phytophthora sojae (Rps). In this study, QTL-sequencing combined with genetic mapping was used to identify in soybean cultivar Xiu94-11 resistance to all isolates tested, exhibiting broad-spectrum PRR resistance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20081809DOI Listing

Health-Related Characteristics of Older Adults Who Attend Congregate Meal Sites in the United States.

Geriatrics (Basel) 2017 Jul 14;2(3). Epub 2017 Jul 14.

Department of Dietetics and Nutrition, Florida International University, Miami, FL 33199, USA.

The purpose of this study was to determine health-related characteristics of a representative sample of older adults who attend congregate meal sites in the United States, and compare races/ethnicities and sexes. Participants were adults, aged 60 years and older, ( = 901) of the . Difficulties with mobility and Activities of Daily Living were common among older adults who attended congregate meals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/geriatrics2030022DOI Listing

Emerging translational science discoveries, clonal approaches and treatment trends in chronic myeloproliferative neoplasms.

Hematol Oncol 2019 Apr 23. Epub 2019 Apr 23.

University of California Irvine, Irvine, CA, USA.

The 60 American Society of Hematology (ASH) held in San Diego in December 2018 was followed by the 13 Post-ASH chronic myeloproliferative neoplasms (MPNs) workshop on the 4 -5 December 2018. This closed annual workshop, first introduced in 2006 by Goldman and Mughal, was organized in collaboration with Alpine Oncology Foundation and allowed experts in preclinical and clinical research in the chronic MPNs to discuss the current scenario, including relevant presentations at ASH, and address pivotal open questions that impact translational research and clinical management. This review is based on the presentations and deliberations at this workshop, and rather than provide a resume of the proceedings, we have selected some of the important translational science and treatment issues which require clarity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hon.2622DOI Listing

Economic evaluations of onchocerciasis interventions: a systematic review and research needs.

Trop Med Int Health 2019 Apr 23. Epub 2019 Apr 23.

London Centre for Neglected Tropical Disease Research, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, UK.

Objective: To provide a systematic review of economic evaluations that have been conducted for onchocerciasis interventions, to summarise current key knowledge and to identify research gaps.

Method: A systematic review of the literature was conducted on the 8 of August 2018 using the PubMed (MEDLINE) and ISI Web of Science electronic databases. No date or language stipulations were applied to the searches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tmi.13241DOI Listing

Rare cancers in childhood and adolescence in Brazil: First report of data from 19 population-based cancer registries.

Cancer 2019 Apr 23. Epub 2019 Apr 23.

IRCCS Foundation, Evaluative Epidemiology Unit, Evaluative Epidemiology Unit, National Cancer Institute, Milan, Italy.

Background: Rare childhood cancer is challenging to define. The Italian Pediatric Rare Tumor (TREP) Study considers rare tumors to include solid malignancies characterized by an annual incidence rate of <2 cases per 1 million and not enrolled in clinical trials. The objective of the current study was to analyze the population incidence rate of rare tumors among children and adolescents (those aged birth-19 years) in Brazil. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/cncr.32121
Publisher Site
http://dx.doi.org/10.1002/cncr.32121DOI Listing
April 2019
1 Read

Trends in Cigar Use in the United States, 2002 to 2016: Diverging Trends by Race/Ethnicity.

Nicotine Tob Res 2019 Apr 23. Epub 2019 Apr 23.

Institute for Implementation Science in Population Health, The City University of New York, New York, NY USA.

Introduction: While there are racial/ethnic differences in cigarette use, little is known about how non-cigarette tobacco use differs among racial/ethnic groups. The current study investigated trends in cigar use from 2002 to 2016, by racial/ethnic group, in nationally representative United States (US) data.

Methods: Data were drawn from the 2002-2016 National Survey on Drug Use and Health (NSDUH) public use data files (total analytic sample n=630,547 including 54,060 past-month cigar users). Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/ntr/advance-article/doi/10.1093/ntr
Publisher Site
http://dx.doi.org/10.1093/ntr/ntz060DOI Listing
April 2019
1 Read

Low dose from external radiation among returning residents to the former evacuation zone in Minamisoma City, Fukushima Prefecture.

J Radiol Prot 2019 Apr 23;39(2):548-563. Epub 2019 Apr 23.

Research Center for Community Health, Minamisoma Municipal General Hospital, Fukushima, Japan. Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

After the 2011 Fukushima Daiichi nuclear power plant accident, evidence on the real-life conditions of returnees to areas once designated as legal no-go zones, including their radiation dose levels, is scarce. In the present study, using a radiation dosimeter and lifestyle survey, we evaluated the lifestyle characteristics and dose levels in 2017 from external exposure among those who returned to the no-go zones after the evacuation orders were lifted. A total of 112 returnees to Odaka district, Minamisoma City, Fukushima Prefecture, were considered and compared to 266 non-returnees. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1361-6498/ab0f87DOI Listing

Increased Incidence of Central Venous Catheter-Related Infection in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-Peritoneal Chemotherapy.

Surg Infect (Larchmt) 2019 Apr 23. Epub 2019 Apr 23.

1 National Centre for Peritoneal Malignancy, Mater Misericordiae University Hospital, Dublin, Ireland.

Cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) is a complex surgical intervention with associated risks. Central venous catheter (CVC) line sepsis is one of a number of potential morbidities. The aim of this study was to calculate the incidence of catheter-related infection (CRI) in a CRS and HIPEC patient population and to assess its influence on length of hospital stay. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/sur.2018.250DOI Listing

Trends in pediatric thyroid cancer incidence in the United States, 1998-2013.

Cancer 2019 Apr 23. Epub 2019 Apr 23.

Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.

Background: Pediatric differentiated thyroid cancer (DTC) rates have increased over time in the United States and worldwide. Improvements in imaging for the diagnosis of DTC have been hypothesized as a potential driver of these increases. This study stratifies temporal trends in pediatric DTC by stage and tumor size to assess whether rates of large, late-stage cancers, which are likely to be clinically meaningful, are increasing over time. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.32125DOI Listing