Annu Rep NMR Spectrosc 2016 7;89:103-121. Epub 2016 Jun 7.
Department of Biochemistry, Molecular Biology, and Biophysics- University of Minnesota, Minneapolis, MN 55455.
Magic angle spinning solid-state NMR (MAS ssNMR) spectroscopy is a powerful method for structure determination of biomacromolecules that are recalcitrant to crystallization (membrane proteins and fibrils). Conventional multidimensional ssNMR methods acquire one experiment at a time. This approach is time consuming and discards orphan (unused) spin operators. Read More