1,454 results match your criteria Annals of transplantation[Journal]


Study of Hepatic Vascular Dynamics Based on Symmetrical Pulsating Perfusion.

Ann Transplant 2019 Apr 19;24:214-222. Epub 2019 Apr 19.

Organization of Advanced Science and Technology, Kobe University, Kobe, Hyogo, Japan.

BACKGROUND The traditionally used perfusion method is constant flow. This study proposes a novel method called Symmetric Pulsating Flow (SPF) and verified that this method is applicable. MATERIAL AND METHODS The fluid dynamic behavior of perfusate in the vessel, the shear stress, and the vascular deformation were simulated based on the bi-directional fluid-structure interaction. Read More

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http://dx.doi.org/10.12659/AOT.913008DOI Listing

Clinical Efficacy of Pretransplant Vaccination for Preventing Herpes Zoster After Living Donor Liver Transplantation in Recipients Age 50 Years and Older.

Ann Transplant 2019 Apr 17;24:208-213. Epub 2019 Apr 17.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

BACKGROUND There have been no reports concerning the efficacy of pretransplant herpes zoster (HZ) vaccination following living donor liver transplantation (LDLT). MATERIAL AND METHODS From January 2013 to May 2016, 24 patients age 50 years and older received vaccination of HZ prior to transplantation and underwent LDLT at a single institution. We compared this to the 1-year HZ incidence of unvaccinated recipients (N=180) who underwent LDLT in the same time period. Read More

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http://dx.doi.org/10.12659/AOT.914213DOI Listing

Endovascular Interventions in Vascular Complications After Simultaneous Pancreas and Kidney Transplantations: A Single-Center Experience.

Ann Transplant 2019 Apr 12;24:199-207. Epub 2019 Apr 12.

Department of Gastroenterological Surgery and Transplantation, Medical Centre of Postraguade Medicine, Warsaw, Poland.

BACKGROUND Vascular failures are serious complications in pancreas transplantation. Open surgery is a reliable and quick intervention method, but it carries a risk of infection and bleeding. Endovascular procedures are rare among patients after a SPK, but are becoming more frequently used. Read More

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http://dx.doi.org/10.12659/AOT.912005DOI Listing
April 2019
1 Read

Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes.

Ann Transplant 2019 Apr 10;24:191-198. Epub 2019 Apr 10.

Centre for Ophthalmology, University of Tübingen, Tübingen, Germany.

BACKGROUND This study investigated the effect of donor-dependent factors on contamination rates of conjunctival swabs of human donor eyes. MATERIAL AND METHODS From July 2015 to September 2017 a total of 1008 conjunctival swabs from 504 consecutive human donor eyes were analyzed. Cross-tabulation, chi-squared tests, and Fisher's exact tests were used to evaluate the effect of donor-dependent factors on contamination rates of conjunctival swabs. Read More

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http://dx.doi.org/10.12659/AOT.912266DOI Listing

Cystic Fibrosis: From Qualification to Lung Transplantation, a Single Center Experience.

Ann Transplant 2019 Apr 5;24:185-190. Epub 2019 Apr 5.

Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Medical University of Silesia, Katowice, Poland.

BACKGROUND Cystic fibrosis (CF) is congenital multisystem disorder, that leads to gradual deterioration of pulmonary function. Advancements in therapy of CF-related lung disease have delayed its progression. However, lung transplantation remains the only therapeutic option for majority of such patients. Read More

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http://dx.doi.org/10.12659/AOT.914328DOI Listing
April 2019
3 Reads

Outcome of Rituximab-Based Treatment for Post-Transplant Lymphoproliferative Disorder After Allogeneic Hematopoietic Stem Cell Transplantation: A Single-Center Experience.

Ann Transplant 2019 Apr 3;24:175-184. Epub 2019 Apr 3.

School of Medicine, Nankai University, Tianjin, China (mainland).

BACKGROUND Post-transplant lymphoproliferative disorder (PTLD) is a rare complication following solid organ transplantation and allogeneic hematopoietic stem cell transplantation (Allo-HSCT), which gives rise to high mortality rates. MATERIAL AND METHODS This was a single-center retrospective analysis based on 27 patients who were diagnosed with PTLD following Allo-HSCT between January 1, 2007 and June 2018 at the Chinese PLA General Hospital. The purpose of this analysis was to investigate responses and prognostic factors of rituximab-based treatment. Read More

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http://dx.doi.org/10.12659/AOT.914101DOI Listing
April 2019
1 Read
1.430 Impact Factor

Clinical Characteristics of Acute Appendicitis in Kidney Transplant Recipients.

Ann Transplant 2019 Mar 26;24:168-173. Epub 2019 Mar 26.

Transplant Research Center, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

BACKGROUND Clinical characteristics of acute appendicitis in kidney transplant recipients may be different from those in the general population due to kidney transplant recipient's immunosuppressive state and position change of appendix caused by graft. MATERIAL AND METHODS Clinical characteristics of 10 cases of acute appendicitis among 2880 cases of kidney transplantation were evaluated, including diagnostic rate, location of appendix and complication in kidney transplant recipients. RESULTS Acute appendicitis was suspected in 9 of 10 patients (90%) with acute appendicitis based on clinical and laboratory findings. Read More

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http://dx.doi.org/10.12659/AOT.914134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446653PMC
March 2019
1 Read

Etiology of Liver Disease and Cardiovascular Abnormalities in Patients on a Liver Transplantation Waiting List.

Ann Transplant 2019 Mar 22;24:162-167. Epub 2019 Mar 22.

1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.

BACKGROUND The classical cardiovascular risk factors and changes in the circulatory system secondary to end-stage liver disease (ESLD) are associated with an increased risk of cardiac abnormalities (CAs) in patients waiting for liver transplantation (LTx). The aim of this study was to assess the relationship between the etiology of liver disease and the presence of CAs in patients qualified for LTx. MATERIAL AND METHODS The study enrolled patients qualified to LTx due to ESLD at the Clinical Hospital of the Medical University of Warsaw between 2013 and 2016. Read More

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http://dx.doi.org/10.12659/AOT.913061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442494PMC
March 2019
3 Reads

A New Approach to Accomplish Intraoperative Cholangiography in Left Lateral Segmentectomy of Living Liver Donation.

Ann Transplant 2019 Mar 19;24:155-161. Epub 2019 Mar 19.

Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University and National Clinical Research Center for Digestive Diseases, Beijing, China (mainland).

BACKGROUND There are 2 main methods of bile duct division in harvesting left lateral segment of a living donor: 1) by intraoperative cholangiography through cystic duct with cholecystectomy, or 2) by direct vision with preoperative magnetic resonance cholangiopancreatography. Here, we present a new approach to cholangiography by using the bile duct stump of the fourth liver segment (B4 stump) to achieve left lateral segmentectomy in pediatric living donor liver transplantation. MATERIAL AND METHODS This was a prospective study of 221 living donors who had undergone intraoperative cholangiography via the B4 stump in the course of left lateral segmentectomy. Read More

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http://dx.doi.org/10.12659/AOT.915400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439928PMC
March 2019
1 Read

Prolonged Duration of Brain Death was Associated with Better Kidney Allograft Function and Survival: A Prospective Cohort Analysis.

Ann Transplant 2019 Mar 15;24:147-154. Epub 2019 Mar 15.

Department of Surgery, Division of Vascular and Transplant Surgery, Radboud University Medical Center, Nijmegen, Netherlands.

BACKGROUND Brain death initiates hemodynamic, immunological, and hormonal changes that potentially compromise organ quality for transplantation. Therefore, it is generally believed that organs should be procured as soon as possible after the declaration of brain death. However, conflicting data exist regarding the impact of brain death duration on long-term graft function and survival. Read More

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http://dx.doi.org/10.12659/AOT.913869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434611PMC
March 2019
1 Read

The Incidence and Risk Factors of Low Oxygenation After Orthotropic Liver Transplantation.

Ann Transplant 2019 Mar 12;24:139-146. Epub 2019 Mar 12.

Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China (mainland).

BACKGROUND This study was designed to observe incidence and risk factors of low oxygenation after orthotropic liver transplantation (OLT). MATERIAL AND METHODS We retrospectively evaluated all adult patients who underwent living-donor OLT between January 1, 2017 and December 31, 2017. Postoperative low oxygenation was defined as PaO₂/FiO₂ <300 mmHg within 24 hours after surgery. Read More

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http://dx.doi.org/10.12659/AOT.913716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429984PMC

Surgical Safety and Efficacy of Third Kidney Transplantation in the Ipsilateral Iliac Fossa.

Ann Transplant 2019 Mar 8;24:132-138. Epub 2019 Mar 8.

Department of Surgery, Division of Hepato-Pancreato-Biliary (HPB) and Transplant Surgery, Rotterdam Transplant Group, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands.

BACKGROUND Kidney re-transplantation is a relevant option for patients who are returning to dialysis after graft failure. However, evidence is lacking to what extend a third kidney transplantation in the ipsilateral iliac fossa is safe and effective. The aim of this study was to investigate the outcomes of third kidney transplantations in the ipsilateral iliac fossa compared to first and second ipsilateral fossa kidney transplantations. Read More

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http://dx.doi.org/10.12659/AOT.913300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420794PMC
March 2019
1 Read

Pure Red Cell Aplasia After Kidney Transplantation: Parvovirus B19 Culprit or Coincidence?

Ann Transplant 2019 Mar 5;24:123-131. Epub 2019 Mar 5.

Department of Nephrology Transplantation and Internal Medicine, Pomeranian Medical University, Szczecin, Poland.

BACKGROUND Anemia is present even in long-term observation after kidney transplantation. Observational study results indicate the presence of chronic post-transplantation anemia in 1 in 3 recipients. An extreme form of erythroid line dysfunction is pure red cell aplasia (PRCA). Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.913663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419532PMC
March 2019
3 Reads
1.430 Impact Factor

Intraoperative Ultrasonography as a Guidance for Dividing Bile Duct During Laparoscopic Living Donor Hepatectomy.

Ann Transplant 2019 Feb 28;24:115-122. Epub 2019 Feb 28.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

BACKGROUND The purpose of this study was to investigate the feasibility of using intraoperative ultrasonography as a guidance in dividing bile duct during laparoscopic donor hepatectomy. MATERIAL AND METHODS Cases of living liver donors who underwent laparoscopic living donor hepatectomy from May 2013 to December 2017 were reviewed. Operative and postoperative data were compared between donors with intraoperative ultrasonography and donors with intraoperative cholangiography. Read More

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http://dx.doi.org/10.12659/AOT.914013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410606PMC
February 2019

Effect of Multidrug-Resistant 1 (MDR1) and CYP3A4*1B Polymorphisms on Cyclosporine-Based Immunosuppressive Therapy in Renal Transplant Patients.

Ann Transplant 2019 Feb 25;24:108-114. Epub 2019 Feb 25.

Department of General Surgery and Transplantation, Pomeranian Medical University, Szczecin, Poland.

BACKGROUND Immunosuppressive drugs such as cyclosporine A (CsA) are characterized by a narrow therapeutic range and high interindividual pharmacokinetic variations. Therefore, the effective monitoring of drug serum level is crucial for successful therapy. This variability can be caused by polymorphisms in genes encoding drug transporters and enzymes responsible for biotransformation. Read More

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http://dx.doi.org/10.12659/AOT.914683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400024PMC
February 2019
1 Read

Pre-Transplant Left Ventricular Geometry and Major Adverse Cardiovascular Events After Kidney Transplantation.

Ann Transplant 2019 Feb 21;24:100-107. Epub 2019 Feb 21.

Kidney Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.

BACKGROUND Preventing major adverse cardiovascular events (MACE) after kidney transplantation motivates pre-transplant cardiac evaluation that includes two-dimensional transthoracic echocardiography (TTE). The relationship of relative wall thickness (RWT) to left ventricular mass index (LVMI) in predicting post-transplant MACE is unclear. MATERIAL AND METHODS In this multi-ethnic Canadian single-center cohort study, we identified 1063 adults undergoing pre-transplant TTE within 1 year pre-transplant and with minimum 6 months of post-kidney transplant follow-up for MACE, defined as a composite of coronary revascularization, myocardial infarction, stroke, and cardiac death. Read More

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http://dx.doi.org/10.12659/AOT.913649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397615PMC
February 2019

Selected Legal Aspects of Donation After Circulatory Death in Poland.

Ann Transplant 2019 Feb 18;24:93-99. Epub 2019 Feb 18.

Department Nephrology, Dialysis, and Internal Diseases, Warsaw Medical University, Warsaw, Poland.

Organ transplantation is one of the most critical ethical topics in law and medicine and a matter of debate in various countries. Lack of organs for engraftment to meet the existing demand has resulted in a substantial crisis due to organ shortage and a rise in the critical conditions of certain waitlisted patients, as well as increased mortality of patients while waiting. Organ shortages for transplantation raised the issue of procurement of organs not only from living donors and cadaveric donors after brain death, but also after circulatory death. Read More

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http://dx.doi.org/10.12659/AOT.912567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394144PMC
February 2019
1 Read

Patients Treated for Central Airway Stenosis After Lung Transplantation Have Persistent Airflow Limitation.

Ann Transplant 2019 Feb 14;24:84-92. Epub 2019 Feb 14.

Department of Respiratory Medicine, Federation of Translational Medicine of Strasbourg (FMTS), University Hospitals, Strasbourg, France.

BACKGROUND Although central airway stenosis (CAS) is a common complication after lung transplantation, its consequences have been poorly evaluated. The objective of our study was to evaluate the impact of CAS on lung function after lung transplantation. MATERIAL AND METHODS All lung transplant recipients from June 2009 to August 2014 in a single center (Strasbourg, France) were retrospectively reviewed. Read More

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http://dx.doi.org/10.12659/AOT.911923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383442PMC
February 2019
1 Read

Comparison of Clinical Outcomes Between Preemptive Transplant and Transplant After a Short Period of Dialysis in Living-Donor Kidney Transplantation: A Propensity-Score-Based Analysis.

Ann Transplant 2019 Feb 11;24:75-83. Epub 2019 Feb 11.

Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

BACKGROUND The permissible extent of pretransplant dialysis for patient and allograft survival is unclear. We assumed that a short period of dialysis before living donor kidney transplantation (LDKT) will show the similar results as preemptive kidney transplantation (PKT). MATERIAL AND METHODS We retrospectively evaluated the outcomes of LDKT according to pretransplant dialysis duration in both unmatched cohorts (n=1984) and propensity-score-matched cohorts (n=986) cohorts. Read More

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http://dx.doi.org/10.12659/AOT.913126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380163PMC
February 2019
8 Reads

Are Females More Prone Than Males to Become Obese After Kidney Transplantation?

Ann Transplant 2019 Jan 29;24:57-61. Epub 2019 Jan 29.

Department of Nephrology and Transplantation Medicine, Wrocław Medical University, Wrocław, Poland.

BACKGROUND Being overweight for kidney transplant recipients can cause serious side effects. Weight gain affects two-thirds of kidney transplant recipients and has been attributed to a more liberal diet after transplantation, recovery of appetite due to lack of uremic toxicity, corticosteroid use, and inadequate lifestyle changes. The aim of this study was to assess gender-dependent profile of body mass index (BMI) changes after kidney transplantation (KTx). Read More

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http://dx.doi.org/10.12659/AOT.912096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367887PMC
January 2019
1 Read

Chimney-Patch Arterial Graft in Kidney or Pancreas Transplantation for Recipients with Heavily Calcified Iliac Arteries.

Ann Transplant 2019 Feb 7;24:70-74. Epub 2019 Feb 7.

Department of Transplant, University of Tennessee Health Science Center, Methodist University Hospital Transplant Institute, Memphis, TN, USA.

Iliac artery calcification is a common phenomenon complicating renal transplantation, particularly in those with diabetes. The potential for vascular clamp injury can threaten the renal allograft, ipsilateral lower extremity, or both. Utilization of internal balloon occlusion can allow for placement of a "Chimney Patch" graft, fashioned from a deceased donor artery, to the calcified vessel, eliminating the risk of clamp injury and minimizing warm ischemic time. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.912744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378857PMC
February 2019
6 Reads

New-Onset Diabetes After Renal Transplantation (NODAT): Is It a Risk Factor for Renal Cell Carcinoma or Renal Failure?

Ann Transplant 2019 Feb 4;24:62-69. Epub 2019 Feb 4.

Department of Urology, General Hospital of Southern Theatre Command of China People's Liberation Army (CPLA), Guangzhou, Guangdong, China (mainland).

BACKGROUND Diabetes mellitus (DM) is a risk factor for renal failure and possibly for renal cell carcinoma (RCC). Post-transplantation DM occurs frequently after solid organ transplantation. We investigated whether new-onset diabetes after renal transplantation (NODAT) is a risk factor for RCC or renal failure. Read More

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http://dx.doi.org/10.12659/AOT.909099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373244PMC
February 2019
3 Reads
1.430 Impact Factor

Long-Term Health-Related Quality of Life in Living Liver Donors.

Ann Transplant 2019 Jan 22;24:45-51. Epub 2019 Jan 22.

Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.

BACKGROUND In living donor liver transplantation (LDLT), 2 patients undergo surgery, and the advantages and disadvantages for both patients should be considered. This study evaluated the long-term quality of life in living liver donors, and its impact on their activities of daily living focusing on mood and mental health. MATERIAL AND METHODS In total, 101 living liver donors (69 female and 32 male patients, median age of 36. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.911109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352752PMC
January 2019
6 Reads

Efficacy and Safety of Delayed Prolonged-Release Tacrolimus Initiation in De Novo Hepatitis C Virus-Negative Orthotopic Liver Transplant Recipients: A Single-Center, Single-Arm, Prospective Study.

Ann Transplant 2019 Jan 18;24:36-44. Epub 2019 Jan 18.

Liver Transplant Unit, University Hospital of Bellvitge, Barcelona, Spain.

BACKGROUND Delaying initiation of tacrolimus after liver transplantation (LT) is a potential renal-sparing strategy. We assessed safety and efficacy of delayed initiation of prolonged-release tacrolimus (PR-T) in de novo LT. MATERIAL AND METHODS This was a single-center, single-arm, prospective, 12-month observational study of hepatitis C virus-negative orthotopic LT patients. Read More

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http://dx.doi.org/10.12659/AOT.912444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346812PMC
January 2019
5 Reads

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Metastases in Solid Organ Graft Recipients: First Experience.

Ann Transplant 2019 Jan 15;24:30-35. Epub 2019 Jan 15.

Department of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany.

BACKGROUND Therapy of peritoneal metastases (PM) in solid organ transplant recipients is challenging. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) might constitute a new therapeutic opportunity for these patients. MATERIAL AND METHODS This was a single-center, retrospective analysis of prospective registry data (NCT03210298) in a tertiary care center between 1. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.911905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346813PMC
January 2019
13 Reads

Kidney Transplantation in Children with Thrombosed Inferior Caval Vein - Atypical Vascular Anastomoses.

Ann Transplant 2019 Jan 11;24:25-29. Epub 2019 Jan 11.

Department of Nephrology, Kidney Transplantation and Arterial Hypertension, Children's Memorial Health Institute, Warsaw, Poland.

BACKGROUND Diffuse thrombosis of iliac veins and IVC has been considered a significant technical obstacle in pediatric kidney transplantation (KT). MATERIAL AND METHODS Between 1984 and 2018, 951 KTs were performed in our institution. In 4 children qualified for KT, diffuse thrombosis of iliac veins or IVC was found. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.912657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338005PMC
January 2019
10 Reads

Pediatric Living-Donor Liver Transplant Recipients without Transition After Reaching Adulthood.

Ann Transplant 2019 Jan 8;24:18-24. Epub 2019 Jan 8.

Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

BACKGROUND Transition to adult care can trigger certain problems for pediatric liver transplant recipients. At our institution, the same transplant team performs both adult and pediatric liver transplantation and post-transplant care; thus, pediatric liver transplant recipients do not have to be transferred. However, it is unclear whether this system affects the recipient's outcome during the transition period. Read More

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http://dx.doi.org/10.12659/AOT.911544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338013PMC
January 2019

Normothermic Machine Perfusion Protects Against Liver Ischemia-Reperfusion Injury During Reduced-Size Liver Transplantation in Pigs.

Ann Transplant 2019 Jan 4;24:9-17. Epub 2019 Jan 4.

Department of Transplantation Surgery, Tianjin First Central Hospital, Tianjin Clinical Research Center for Organ Transplantation, Tianjin, China (mainland).

BACKGROUND Normothermic machine perfusion (NMP) preservation is superior to cold preservation during reduced-size liver transplantation (RSLT) in pigs. However, the mechanism of this protective effect has not been explained. We aimed to compare the effects of NMP preservation with that of cold preservation (CS) in protecting against ischemia-reperfusion injury (IRI) during RSLT in pigs. Read More

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http://dx.doi.org/10.12659/AOT.910774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338011PMC
January 2019
13 Reads
1.430 Impact Factor

Somatostatin Therapy in Patients with Massive Ascites After Liver Transplantation.

Ann Transplant 2019 Jan 1;24:1-8. Epub 2019 Jan 1.

Division of General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

BACKGROUND Patients with massive ascites (MA) after liver transplantation (LT, defined here as daily ascitic drainage more than 1000 ml per day for more than 7 days after liver transplantation) are at increased risks of infection, hypoalbuminemia, graft loss, and even mortality. The aim of this retrospective cohort study was to investigate the effects of somatostatin on patients with MA after LT. MATERIAL AND METHODS Twenty-eight patients with liver cirrhosis or hepatocellular carcinoma who underwent LT complicated by MA postoperatively were included. Read More

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http://dx.doi.org/10.12659/AOT.911788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327785PMC
January 2019
1 Read

Feasibility of Laparoscopic Combined Para-Orthotopic Pancreas and Orthotopic Kidney Transplantation: Initial Research with a Pig Model.

Ann Transplant 2018 Dec 27;23:879-887. Epub 2018 Dec 27.

Institute of Urology, Capital Medical University, Beijing, China (mainland).

BACKGROUND The aim of this study was to investigate the feasibility of laparoscopic combined para-orthotopic pancreas and orthotopic kidney transplantation in a pig model. MATERIAL AND METHODS Twelve white female pigs, (4-5 months old, weight range 40-45 kg) were used as donors and recipients, and 6 laparoscopic-combined pancreas and kidney transplantations were performed. After bilateral nephrectomy, the pancreatic artery and vein were anastomosed to the right renal artery and vein, respectively, and the pancreatic fluid was diverted to the duodenum or jejunum. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.913221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319439PMC
December 2018
16 Reads

Correlation Between Stem and Progenitor Cells Number and Immune Response in Patients After Allogeneic Kidney Transplant.

Ann Transplant 2018 Dec 21;23:874-878. Epub 2018 Dec 21.

Department of General Surgery and Transplantation, Pomeranian Medical University, Szczecin, Poland.

BACKGROUND Stem and progenitor cells are of great interest in all medical procedures involving tissue regeneration. There is a consensus that the use of stem cells after solid organ transplantation may play a role in tissue repair and in immunosuppression. The aim of this study was to determine possible relations between stem cell count and the immune response in a group of patients after kidney transplantation. Read More

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http://dx.doi.org/10.12659/AOT.912686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319141PMC
December 2018

Pulmonary Artery Systolic Pressure Measured Intraoperatively by Right Heart Catheterization Is a Predictor of Kidney Transplant Recipient Survival.

Ann Transplant 2018 Dec 18;23:867-873. Epub 2018 Dec 18.

Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

BACKGROUND The effect of pulmonary artery systolic pressure (PASP) measured by Swan-Ganz right heart catheter (SG-RHC) on kidney transplant recipient survival has not been previously studied. The objective of this study was to assess the relationships between PASP measured via SG-RHC, done intraoperatively at the time of initiating anesthesia at the beginning of kidney transplant surgery, and patient survival. Multiple comorbidities, time on dialysis before the transplantation, and graft function were also analyzed in our study. Read More

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http://dx.doi.org/10.12659/AOT.911176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319438PMC
December 2018
2 Reads
1.430 Impact Factor

Healthcare Resource Use, Cost, and Sick Leave Following Kidney Transplantation in Sweden: A Population-Based, 5-Year, Retrospective Study of Outcomes: COIN.

Ann Transplant 2018 Dec 14;23:852-866. Epub 2018 Dec 14.

Department of Transplantation Surgery, Karolinska University Hospital, Huddinge, Sweden.

BACKGROUND Improved understanding of the impact of kidney transplantation on healthcare resource use/costs and loss of productivity could aid decision making about funding allocation and resources needed for the treatment of chronic kidney disease in stage 5. MATERIAL AND METHODS This was a retrospective study utilizing data from Swedish national health registers of patients undergoing kidney transplantation. Primary outcomes were renal disease-related healthcare resource utilization and costs during the 5 years after transplantation. Read More

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http://dx.doi.org/10.12659/AOT.911843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302995PMC
December 2018

Success of kidney transplantations from deceased donors with acute kidney injury.

Ann Transplant 2018 Dec 7;23:836-844. Epub 2018 Dec 7.

Department of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany.

BACKGROUND The acceptance of organs from deceased donors with acute kidney injury (AKI) varies considerably, with uncertain outcomes. The current organ shortage has led to increased use of marginal donor organs. MATERIAL AND METHODS This retrospective, single-center study included 642 patients who underwent kidney allograft transplantation between 2005 and 2016. Read More

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http://dx.doi.org/10.12659/AOT.912660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298175PMC
December 2018

Percutaneous Treatment of Biliary Strictures After Pediatric Liver Transplantation.

Ann Transplant 2018 Dec 11;23:845-851. Epub 2018 Dec 11.

Department of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

BACKGROUND Biliary strictures (BS) are frequent after pediatric liver transplantation (LTx) and in spite of ongoing progress, they remain a significant cause of morbidity. In children, the majority of reconstruction is hepatico-jejunal anastomosis (HJA). The aim of this study was to analyze our experience in percutaneous transhepatic treatment of BS. Read More

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http://dx.doi.org/10.12659/AOT.910528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299781PMC
December 2018
13 Reads

A Single-Center Experience with an Intensivist-Led Brain-Dead Donor Management Program.

Ann Transplant 2018 Dec 4;23:828-835. Epub 2018 Dec 4.

Department of Surgery and Critical Care Medicine, Ewha Womans University College of Medicine, Seoul, South Korea.

BACKGROUND The aim of this study is to report our experience of brain-dead donor management by a dedicated intensivist who had wide experience in treatment of hemodynamically unstable patient and to suggest a role for intensivists in organ donation. MATERIAL AND METHODS The management of brain-dead donors was performed by experienced intensivists. The hospital medical records and data from the Korean Network of Organ Sharing from August 2013 to December 2016 were reviewed retrospectively. Read More

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http://dx.doi.org/10.12659/AOT.912025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289034PMC
December 2018

Evaluation Using an Isolated Reperfusion Model for Porcine Liver Donated After Cardiac Death Preserved with Oxygenated Hypothermic Machine Perfusion.

Ann Transplant 2018 Nov 27;23:822-827. Epub 2018 Nov 27.

Department of Mechanical Engineering, Tokyo Metropolitan University, Hachioji, Tokyo, Japan.

BACKGROUND Machine perfusion techniques offer a solution to the serious organ shortage. However, to assess the effects of machine perfusion, many detailed studies are required. In this study, an ex vivo reperfusion model using diluted autologous blood was confirmed to evaluate the utility of machine preservation for livers donated after cardiac death (DCD). Read More

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http://dx.doi.org/10.12659/AOT.910008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284356PMC
November 2018
11 Reads

Protective Effects of Apoptosis of Kupffer Cells Induced by Zoledronate Liposomes Following Hepatic Ischemia-Reperfusion Injury.

Ann Transplant 2018 Nov 23;23:815-821. Epub 2018 Nov 23.

Department of General Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, China (mainland).

BACKGROUND The goal of this study was to observe the effect of the apoptosis of Kupffer cells (KCs) selectively induced by zoledronate liposomes following the hepatic ischemia-reperfusion injury (IRI) in the rat liver transplantation model and to explore its mechanisms. MATERIAL AND METHODS The rat liver transplantation model was established using the improved Kamada method. Male Sprague Dawley rats were randomly divided into 3 groups: no liver transplantation or drug treatment (Group A); donor rats were injected with 1 mL normal saline through the tail vein for 3 continuous days before transplantation, and the donor liver was preserved in cold for 2 hours (Group B); donor rats were injected with 1 mL zoledronate liposomes (0. Read More

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http://dx.doi.org/10.12659/AOT.909982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266722PMC
November 2018
10 Reads

Impact of Donor Pre-Procurement Cardiac Arrest (PPCA) on Clinical Outcomes in Liver Transplantation.

Ann Transplant 2018 Nov 20;23:808-814. Epub 2018 Nov 20.

Transplant Division, Department of Surgery, Indiana University, School of Medicine, Indianapolis, IN, USA.

BACKGROUND Transplantation of liver grafts from deceased donors who experienced cardiac arrest prior to liver procurement is now common. This single-center study analyzed the impact of pre-donation arrest time on clinical outcomes in liver transplantation. MATERIAL AND METHODS Records of all orthotopic liver transplants performed at a single center over a 15-year period were reviewed. Read More

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http://dx.doi.org/10.12659/AOT.910387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259573PMC
November 2018
15 Reads

Results of Adult Living Donor Liver Transplantation with Sixth-Decade Donors: A Propensity Score Matching Study in a High-Volume Institution.

Ann Transplant 2018 Nov 16;23:802-807. Epub 2018 Nov 16.

Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

BACKGROUND We assessed the prognostic impact of donor age on the outcome of adult living donor liver transplantation (LDLT). MATERIAL AND METHODS The study population comprised adult donor and recipients of right lobe grafts for LDLT performed from January 2005 to December 2016. There were 35 living donors aged ≥50 years (old-age donor group). Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.911550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251075PMC
November 2018
8 Reads

Recurrence of Hepatitis B Infection in Liver Transplant Patients Receiving Long-Term Hepatitis B Immunoglobulin Prophylaxis.

Ann Transplant 2018 Nov 13;23:789-801. Epub 2018 Nov 13.

Transplant Centre, Faculty of Medicine, Azienda Ospedaliera Policlinico Tor Vergata, Rome, Italy.

BACKGROUND Long-term real-world data are relatively sparse regarding recurrence of chronic hepatitis B virus (HBV) infection after liver transplantation using hepatitis B immunoglobulin (HBIg) and nucleos(t)ide analogue (NUC) prophylaxis. MATERIAL AND METHODS Data from 371 adults transplanted for HBV-related disease at 20 European centers and given HBIg for ³12 months ± NUC therapy were analyzed retrospectively. RESULTS HBIg comprised Hepatect® (iv HBIgB; n=299), subcutaneous Zutectra® (sc HBIg, n=236), and other HBIg preparations (n=130); 93. Read More

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http://dx.doi.org/10.12659/AOT.910176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249983PMC
November 2018
32 Reads

Colonoscopy as Part of Pre-Transplant Work-Up in Successful Kidney Transplant Candidates: Single-Center Experience and Review of Literature.

Ann Transplant 2018 Nov 9;23:782-788. Epub 2018 Nov 9.

Department of Nephrology, Transplantology, and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland.

BACKGROUND Screening colonoscopy is not obligatory in kidney pre-transplant work-up guidelines. According to recommendations, only transplant recipients over age 50 years should be screened. The aim of this study was to characterize endoscopic findings revealed as part of pre-transplant work-up. Read More

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http://dx.doi.org/10.12659/AOT.910658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247820PMC
November 2018
3 Reads

Association of Kidney Donor Risk Index with the Outcome after Kidney Transplantation in the Eurotransplant Senior Program.

Ann Transplant 2018 Nov 6;23:775-781. Epub 2018 Nov 6.

Medical Clinic, Section of Nephrology and Infectious Diseases, Gemeinschaftsklinikum Mittelrhein, Koblenz, Germany.

BACKGROUND We evaluated the Kidney Donor Risk Index (KDRI) scoring system for kidney transplantation in the Eurotransplant Senior Program (ESP) that allocates kidneys from older donors to older recipients (≥65 years). MATERIAL AND METHODS We retrospectively analyzed data of 37 kidney transplant recipients and 36 kidney donors who participated in kidney transplantation program according to the ESP at our center from January 2004 until December 2013. RESULTS Mean recipient and donor age was 67. Read More

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http://dx.doi.org/10.12659/AOT.909622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248015PMC
November 2018
30 Reads

Risk Factors for Intensive Care Unit Readmission After Liver Transplantation: A Retrospective Cohort Study.

Ann Transplant 2018 Nov 2;23:767-774. Epub 2018 Nov 2.

Department of Anesthesiology, Seoul National University College of Medicine, Seoul, South Korea.

BACKGROUND Most liver transplant patients require Intensive Care Unit (ICU) care in the immediate postoperative period and some patients require readmission to the ICU before discharge from the hospital. A retrospective cohort study was conducted to identify risk factors for ICU readmission after liver transplantation. MATERIAL AND METHODS Adult patients who underwent living donor or deceased donor liver transplantation at Seoul National University Hospital between 2004 and 2015 were included. Read More

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http://dx.doi.org/10.12659/AOT.911589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248006PMC
November 2018
27 Reads

Comprehensive Evaluation of a Donated After Circulatory Death (DCD) Donor Liver Model in Minipigs.

Ann Transplant 2018 Oct 30;23:758-766. Epub 2018 Oct 30.

Department of Hepatobiliary Surgery and Organ Transplantation, The First Hospital of China Medical University, Shenyang, Liaoning, China (mainland).

BACKGROUND Graft livers from donors after death from circulatory disease (DCD) often suffer injury from severe ischemia or hypoxia before resection. Thus, earlier evaluation of these livers is critical for the survival of recipients. MATERIAL AND METHODS In our study, 18 minipigs, as DCD donor liver models, were evenly divided into a warm ischemia time (WIT) group and a hypoxia plus ischemia group. Read More

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http://dx.doi.org/10.12659/AOT.911072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248047PMC
October 2018

Association Between Renal Dysfunction and Major Adverse Cardiac Events After Liver Transplantation: Evidence from an International Randomized Trial of Everolimus-Based Immunosuppression.

Ann Transplant 2018 Oct 26;23:751-757. Epub 2018 Oct 26.

Transplantation Center, Cleveland Clinic, Cleveland, OH, USA.

BACKGROUND Prospective evidence is lacking regarding the association between renal dysfunction and cardiovascular events after liver transplantation. MATERIAL AND METHODS Data were analyzed post hoc regarding renal function and major adverse cardiac events in a two-year prospective trial of de novo liver transplant recipients randomized at 30 days post-transplant to (i) everolimus [EVR]/reduced tacrolimus [EVR/rTAC] (ii) EVR with tacrolimus discontinued [TAC Elimination] or (iii) standard tacrolimus [TAC Control]. RESULTS By month 24 post-transplant, 32/716 patients had experienced a first major cardiac event (4. Read More

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https://www.annalsoftransplantation.com/abstract/index/idArt
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http://dx.doi.org/10.12659/AOT.911030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248043PMC
October 2018
6 Reads

Everolimus Use for Intolerance or Failure of Baseline Immunosuppression in Adult Heart and Lung Transplantation.

Ann Transplant 2018 Oct 23;23:744-750. Epub 2018 Oct 23.

Richard DeVos Heart and Lung Transplant Program, Spectrum Health, Grand Rapids, MI, USA.

BACKGROUND Everolimus can be utilized after heart or lung transplantation to reduce calcineurin inhibitor associated nephrotoxicity, due to cell cycle inhibitor adverse effects, and as adjunct therapy for rejection, cardiac allograft vasculopathy, and bronchiolitis obliterans syndrome. MATERIAL AND METHODS A single-center, retrospective cohort study was conducted including 51 adult heart transplant patients (n=32) and lung transplant patients (n=19) started on everolimus due to immunosuppressive therapy intolerance or failure, between 2010 and 2017. Everolimus indication, response, efficacy, and tolerability were assessed. Read More

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http://dx.doi.org/10.12659/AOT.910952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248067PMC
October 2018
3 Reads

Clinical Outcomes of Tuberculosis in Recipients After Living Donor Liver Transplantation.

Ann Transplant 2018 Oct 19;23:733-743. Epub 2018 Oct 19.

Liver Transplantation Center and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

BACKGROUND This study aimed to determine clinical outcomes using various drugs during tuberculosis (TB) treatment among living donor liver transplant (LDLT) recipients with TB and to assess the impact of performing LDLT in patients with active TB at the time of LDLT. MATERIAL AND METHODS Out of 1313 LDLT performed from June 1994 to May 2016, 26 (2%) adult patients diagnosed with active TB were included in this study. Active TB was diagnosed using either TB culture, PCR, and/or tissue biopsy. Read More

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http://dx.doi.org/10.12659/AOT.911034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248277PMC
October 2018
4 Reads