Search our Database of Scientific Publications and Authors

I’m looking for a

    8739 results match your criteria Annals of surgical oncology[Journal]

    1 OF 175

    Individualized Treatment Sequencing Selection Contributes to Optimized Survival in Patients with Rectal Cancer and Synchronous Liver Metastases.
    Ann Surg Oncol 2017 Sep 19. Epub 2017 Sep 19.
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Background: The optimal treatment sequence for patients with advanced rectal cancer and synchronous resectable liver metastases is controversial. We examined the outcomes associated with an individualized selection of classic, reversed, or combined approaches.

    Methods: Between 1999 and 2014, 268 patients with rectal cancer and synchronous liver-only metastases underwent curative-intent multimodality therapy. Read More

    Inspection of Perirectal Lymph Nodes by One-Step Nucleic Acid Amplification Predicts Lateral Lymph Node Metastasis in Advanced Rectal Cancer.
    Ann Surg Oncol 2017 Sep 18. Epub 2017 Sep 18.
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita City, Osaka, Japan.
    Background: Lateral lymph node dissection (LLND) is performed for advanced rectal cancers in Japan; however, it can cause sexual and urinary dysfunction. The incidence of lateral LN metastasis is estimated at 7-13.9%; therefore, excessive rectal surgery with LLND should be avoided, especially for prophylactic purposes. Read More

    Tumor Biology Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients Presenting with Locally Advanced Breast Cancer.
    Ann Surg Oncol 2017 Sep 15. Epub 2017 Sep 15.
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Background: Neoadjuvant chemotherapy (NAC) is used to convert patients with inoperable locally advanced breast cancer (LABC) to operability, but has not traditionally been used to avoid mastectomy or axillary dissection in this subset.

    Objective: The purpose of this study was to determine the rates of pathologic complete response (pCR) in LABC patients, and identify factors predictive of pCR to determine if responding patients might be suitable for limited surgery.

    Methods: From 2006 to 2016, 1522 patients received NAC followed by surgery; 321 had advanced disease in the breast (cT4) and/or in the nodes (cN2/N3). Read More

    Radioactive Seed Localization Versus Wire-Guided Localization for Nonpalpable Breast Cancer: A Cost and Operating Room Efficiency Analysis.
    Ann Surg Oncol 2017 Sep 14. Epub 2017 Sep 14.
    Division of General Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.
    Background: This study aimed to compare the cost and resource use between our first-year experience using breast-conserving surgery (BCS) with radioactive seed localization (RSL) and the previous-year standard practice of BCS with wire-guided localization (WGL) for patients with nonpalpable breast cancer at a large Canadian tertiary center.

    Methods: For this retrospective cohort study, data for BCS cases with RSL was collected from 1 April 2015 to 31 March 2016 and for BCS cases with WGL from 1 April 2014 to 31 March 2015.

    Results: The study compared 153 WGL patients with 194 RSL patients. Read More

    Validation of the 8th Edition of the AJCC TNM Staging System for Gastric Cancer using the National Cancer Database.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Gastroenterological Center, Cancer Institute Hospital, Tokyo, Japan.
    Background: The 8th edition AJCC gastric cancer staging manual was refined using Japanese and Korean data from the International Gastric Cancer Association (IGCA). This study evaluated the eighth edition's validity for U.S. Read More

    External Validation of the Prognostic Nomogram (COMPASS) for Patients with Peritoneal Carcinomatosis of Colorectal Cancer.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Department of Abdominal Surgery, University Hospitals of Leuven, Louvain, Belgium.
    Background: To optimize outcome, selection of patients for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is critical. Recently, Simkens et al.7 evaluated the peritoneal surface disease severity score (PSDSS) and suggested a new prognostic nomogram, the colorectal peritoneal metastases prognostic surgical score (COMPASS) based on age, peritoneal carcinomatosis index score, locoregional lymph node status, and signet ring cell histology. Read More

    External Beam Radiation Therapy for Resectable Soft Tissue Sarcoma: A Systematic Review and Meta-Analysis.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Department of General, Visceral and Transplantation Surgery, Ludwig Maximilian University Hospital, Marchioninistr. 15, 81377, Munich, Germany.
    Purpose: The aim of this study was to evaluate the role of preoperative and postoperative external beam radiation therapy (EBRT) in the treatment of resectable soft tissue sarcomas (STSs) of different tumor locations.

    Methods: A systematic literature search was performed to identify studies investigating the effects of EBRT (versus no EBRT) on local recurrence (LR) and overall survival (OS) or comparing different EBRT sequences. Random effects meta-analyses were calculated and presented as cumulative odds ratios (ORs). Read More

    The Impact of Nodal Dissection on Staging in Adrenocortical Carcinoma.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Department of Surgery, New York Presbyterian Hospital - Weill Cornell Medicine, New York, NY, USA.
    Background: The role of lymphadenectomy in adrenocortical carcinoma (ACC) is controversial, and formal lymph node (LN) dissection is not routine. We sought to determine the minimum number of LNs that must be examined to accurately identify a patient as node negative.

    Methods: The National Cancer Database was used to identify patients diagnosed with ACC from 2004 to 2013 who underwent surgical resection. Read More

    Benefit of Adjuvant Radiotherapy for Local Control, Distant Metastasis, and Survival Outcomes in Patients with Localized Soft Tissue Sarcoma: Comparative Effectiveness Analysis of an Observational Cohort Study.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
    Background: This study aimed to quantify the benefit of adjuvant radiotherapy (AXRT) for local control, distant metastasis, and long-term survival outcomes in patients with localized soft tissue sarcoma (STS).

    Methods: This single-center retrospective observational study enrolled 433 STS patients who underwent surgery with curative intent. An inverse probability of treatment-weighted (IPTW) analysis was implemented to account rigorously for imbalances in prognostic variables between the adjuvant treatment groups. Read More

    The Oncologic Impact of Postoperative Complications Following Resection of Truncal and Extremity Soft Tissue Sarcomas.
    Ann Surg Oncol 2017 Sep 11. Epub 2017 Sep 11.
    Division of Surgical Oncology, Department of Surgery, Emory Winship Cancer Institute, Emory University, Atlanta, GA, USA.
    Introduction: Postoperative complications (POCs) negatively impact oncologic outcomes in some malignancies; however, little is known regarding their effect in soft tissue sarcoma (STS). The aim of this study was to determine the impact of POCs on survival after resection of truncal and extremity STS.

    Methods: All patients who underwent resection for a primary truncal or extremity STS at a single academic institution from 2000 to 2015 were included and analyzed. Read More

    Long-Term Follow-Up of Desmoid Fibromatosis Treated with PF-03084014, an Oral Gamma Secretase Inhibitor.
    Ann Surg Oncol 2017 Sep 8. Epub 2017 Sep 8.
    Division of Medical Oncology, University of Colorado Denver School of Medicine - Anschutz Medical Campus, Aurora, CO, USA.
    Background: Desmoid fibromatosis is a fibroblastic neoplasm driven by aberrations within the WNT pathway, exhibiting mutations in β-catenin or APC. We review the long-term follow-up of patients in a phase I study treated with an oral gamma secretase inhibitor, PF-03084014.

    Methods: PF-03084014 was administered orally at doses ranging from 20 to 330 mg twice daily. Read More

    Microsurgical Reconstruction Following Oncologic Resection in Pediatric Patients: A 15-Year Experience.
    Ann Surg Oncol 2017 Sep 7. Epub 2017 Sep 7.
    Department of Plastic Surgery, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
    Background: Free tissue transfer in the pediatric population is a challenging endeavor, even for experienced microsurgeons. Some surgeons argue these cases can be limited by vessel size and spasticity and should be undertaken only when absolutely necessary. We present a 15-year experience examining outcomes of free tissue transfer in pediatric oncologic patients. Read More

    Clinical Predictors of Malignancy in Patients with Pheochromocytoma and Paraganglioma.
    Ann Surg Oncol 2017 Sep 7. Epub 2017 Sep 7.
    Division of Endocrine Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
    Background And Purpose: Factors associated with malignancy in patients with pheochromocytoma (adrenal tumors, Pheo) and paraganglioma (extra-adrenal, PGL) are not well-defined and all patients require lifelong surveillance. The primary aim of our study was to determine genetic and clinical variables associated with malignancy in patients with Pheo/PGL.

    Methods: Single institution retrospective review was performed of all patients who underwent surgery (1/95-1/15) for Pheo/PGL. Read More

    Patient Age and Tumor Subtype Predict the Extent of Axillary Surgery Among Breast Cancer Patients Eligible for the American College of Surgeons Oncology Group Trial Z0011.
    Ann Surg Oncol 2017 Sep 6. Epub 2017 Sep 6.
    Department of Surgery, Duke University Medical Center, Durham, NC, USA.
    Background: The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial established the safety of omitting axillary lymph node dissection (ALND) for early-stage breast cancer patients with limited nodal disease undergoing lumpectomy. We examined the extent of axillary surgery among women eligible for Z0011 based on patient age and tumor subtype.

    Methods: Patients with cT1-2, cN0 breast cancers and one or two positive nodes diagnosed from 2009 to 2014 and treated with lumpectomy were identified in the National Cancer Data Base. Read More

    Redefining the Positive Margin in Pancreatic Cancer: Impact on Patterns of Failure, Long-Term Survival and Adjuvant Therapy.
    Ann Surg Oncol 2017 Sep 5. Epub 2017 Sep 5.
    Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
    Purpose: There is debate regarding the definition and clinical significance of margin clearance in pancreatic ductal adenocarcinoma (PDA). A comprehensive archival analysis of surgical resection margins was performed to determine the effect on locoregional recurrence and survival, and the impact of adjuvant therapy in PDA.

    Methods: We identified 105 patients with resected PDA. Read More

    Prognostic Value of the Age-Adjusted Charlson Comorbidity Index (ACCI) on Short- and Long-Term Outcome in Patients with Advanced Primary Epithelial Ovarian Cancer.
    Ann Surg Oncol 2017 Sep 5. Epub 2017 Sep 5.
    Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung, Essen, Germany.
    Background: We evaluated the prognostic impact of the age-adjusted Charlson Comorbidity Index (ACCI) on both postoperative morbidity and overall survival (OS) in patients with advanced epithelial ovarian cancer (EOC) treated at a tertiary gynecologic cancer center.

    Patients And Methods: Exploratory analysis of our prospectively documented tumor registry was performed. Data of all consecutive patients with stage IIIB-IV ovarian cancer who underwent primary cytoreductive surgery (PDS) from January 2000 to June 2016 were analyzed. Read More

    Anatomy of the Transverse Mesocolon Based on Embryology for Laparoscopic Complete Mesocolic Excision of Right-Sided Colon Cancer.
    Ann Surg Oncol 2017 Sep 5. Epub 2017 Sep 5.
    Division of Gastrointestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
    Background: To treat colon cancer via complete mesocolic excision (CME) with central vascular ligation (CVL), dissection along the embryologic fusion planes is required. However, this surgery is difficult, especially for right-sided colon cancer, because the anatomy and embryology of the transverse mesocolon are not familiar to gastrointestinal surgeons.

    Methods: In this video article, the anatomic details of the transverse mesocolon based on embryology are illustrated with a focus on the venous anatomy. Read More

    Visceral Adiposity and Sarcopenic Visceral Obesity are Associated with Poor Prognosis After Resection of Pancreatic Cancer.
    Ann Surg Oncol 2017 Sep 5. Epub 2017 Sep 5.
    Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
    Background: Visceral fat accumulation and muscle depletion have been identified as poor prognostic factors for various cancers. However, the significance of visceral adiposity and sarcopenic visceral obesity on outcomes after resection of pancreatic cancer remains unclear.

    Methods: A retrospective analysis of 301 patients who underwent resection for localized pancreatic cancer between 2004 and 2015 was performed. Read More

    Negative Impact of Skeletal Muscle Wasting After Neoadjuvant Chemotherapy Followed by Surgery on Survival for Patients with Thoracic Esophageal Cancer.
    Ann Surg Oncol 2017 Aug 31. Epub 2017 Aug 31.
    Division of Gastrointestinal Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
    Background: Skeletal muscle wasting during curative treatment is an important issue faced by esophageal cancer patients. However, it has not been clarified whether skeletal muscle change during neoadjuvant chemotherapy followed by surgery adversely affects prognosis. This study aimed to determine the relation between skeletal muscle change and survival for patients with advanced esophageal cancer who underwent neoadjuvant chemotherapy followed by surgery. Read More

    A Review of Thoracic and Mediastinal Cytoreductive Techniques in Advanced Ovarian Cancer: Extending the Boundaries.
    Ann Surg Oncol 2017 Aug 31. Epub 2017 Aug 31.
    NHS Trust, West London Gynecological Cancer Centre, Imperial College, London, UK.
    The aim of this study was to review the surgical and clinical outcomes of intrathoracic and mediastinal surgical cytoreduction in stage IV epithelial ovarian cancer (EOC). Relevant articles were identified from MEDLINE and EMBASE. Only analyses or reports that described actual intrathoracic cytoreduction via pleurectomy and/or resection of cardiophrenic/mediastinal lymph nodes were included. Read More

    Patients Treated with Preoperative Chemoradiation for Pancreatic Ductal Adenocarcinoma have Impaired Bone Density, a Predictor of Distant Metastasis.
    Ann Surg Oncol 2017 Aug 28. Epub 2017 Aug 28.
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2-2 (E2), Suita, Osaka, 565-0871, Japan.
    Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal neoplasm that spreads to surrounding tissue or distant sites. This study investigated distant metastases in PDAC patients with or without preoperative chemoradiation therapy (CRT), focusing on vitamin D levels and bone density.

    Methods: This study included 146 patients with PDAC who underwent surgery from 2007 to 2014. Read More

    Conversion of Minimally Invasive Distal Pancreatectomy: Predictors and Outcomes.
    Ann Surg Oncol 2017 Aug 28. Epub 2017 Aug 28.
    Division of Surgical Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
    Background: Data on the risk factors for conversion during minimally invasive distal pancreatectomy (MIDP) and its effect on postoperative outcomes are limited.

    Methods: This retrospective study used the pancreas-targeted American College of Surgeons National Surgical Quality Improvement Program database to compare MIDP requiring unplanned conversion with completed MIDP and open distal pancreatectomy (ODP).

    Results: Of the 2926 cases identified in this study, 48. Read More

    Conversion to Complete Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Malignant Peritoneal Mesothelioma After Bidirectional Chemotherapy.
    Ann Surg Oncol 2017 Aug 28. Epub 2017 Aug 28.
    Department of Visceral and Oncological Surgery, Gustave Roussy, Villejuif Cedex, France.
    Background: This report aims to describe preliminary results concerning secondary resectability after bidirectional chemotherapy for initially unresectable malignant peritoneal mesothelioma (MPM).

    Methods: Between January 2013 and January 2016, 20 consecutive patients treated for diffuse MPM not suitable for upfront surgery received bidirectional chemotherapy associating intraperitoneal and systemic chemotherapy. Evaluation of the response to chemotherapy was assessed clinically and by laparoscopy. Read More

    Surgical Outcomes of Isolated Malignant Pulmonary Nodules in Patients with a History of Breast Cancer.
    Ann Surg Oncol 2017 Aug 28. Epub 2017 Aug 28.
    Department of Thoracic Surgery, Shanghai Cancer Center, Fudan University, Shanghai, China.
    Background: The role of surgery for isolated malignant pulmonary nodules in breast cancer patients remains unclear.

    Methods: A total of 1286 consecutive breast cancer patients with pulmonary nodules detected by thoracic computed tomography (CT) or positron emission tomography (PET)/CT scan at Shanghai Cancer Center, Fudan University, were reviewed. Overall, 147 breast cancer patients with isolated malignant pulmonary nodules receiving surgery and/or chemotherapy were enrolled in the study. Read More

    Erratum to: Transoral Resection of Human Papillomavirus (HPV)-Positive Squamous Cell Carcinoma of the Oropharynx: Outcomes with and Without Adjuvant Therapy.
    Ann Surg Oncol 2017 Aug 28. Epub 2017 Aug 28.
    Head and Neck Surgery Center of Florida, Florida Hospital Celebration Health and Florida Hospital Cancer Institute, Celebration, FL, USA.

    Utility of Serum Inflammatory Markers for Predicting Microvascular Invasion and Survival for Patients with Hepatocellular Carcinoma.
    Ann Surg Oncol 2017 Aug 24. Epub 2017 Aug 24.
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Background: Preoperative serum inflammatory markers have been correlated with outcome after resection of hepatocellular carcinoma (HCC), but studies have had conflicting results. This study aimed to evaluate the association of six inflammatory markers with recurrence-free survival (RFS), overall survival (OS), and microvascular invasion (MVI), a well-known prognostic factor.

    Methods: This study investigated 370 patients who underwent resection of HCC from 1992 to 2016, retrospectively evaluating their inflammatory indices and individual components including their neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), prognostic nutritional index (PNI), aspartate aminotransferase-to-platelet ratio index (APRI), and aspartate aminotransferase-to-neutrophil ratio index (ANRI). Read More

    Adjuvant Chemoradiotherapy for Non-Pretreated Gastric Cancer.
    Ann Surg Oncol 2017 Aug 22. Epub 2017 Aug 22.
    Department of Medical Oncology, Academic Medical Center, Amsterdam, The Netherlands.
    Background: While the curative approach to gastric cancer includes perioperative regimens in several countries, a substantial proportion of patients may not receive treatment prior to surgery. This study examines the adjuvant provision of chemoradiotherapy (CRT) for non-pretreated patients with cancer of the stomach including the gastric cardia.

    Methods: All surgically treated patients with primary adenocarcinoma of the stomach and gastric cardia diagnosed between January 2004-December 2013 were selected from the Netherlands Cancer Registry. Read More

    Flat Epithelial Atypia on Core Biopsy and Upgrade to Cancer: a Systematic Review and Meta-Analysis.
    Ann Surg Oncol 2017 Aug 22. Epub 2017 Aug 22.
    Department of Surgery, Mayo Clinic, Rochester, MN, USA.
    Background: No consensus exists on whether flat epithelial atypia (FEA) diagnosed percutaneously should be surgically excised. A systematic review and meta-analysis of the frequency of upgrade to cancer or an atypical ductal hyperplasia (ADH) at surgical excision of FEA was performed.

    Methods: Embase, MEDLINE, Scopus, and Web of Science databases from January 2003 to November 2015 were searched. Read More

    Utility of Appendiceal Calcifications Detected on Computed Tomography as a Predictor for an Underlying Appendiceal Epithelial Neoplasm.
    Ann Surg Oncol 2017 Aug 22. Epub 2017 Aug 22.
    Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Background: Mucinous appendiceal neoplasms can contain radiopaque calcifications. Whether appendiceal radiographic calcifications indicate the presence of an appendiceal epithelial neoplasm is unknown. This study aimed to determine whether appendiceal calcifications detected by computed tomography (CT) correlate with the presence of appendiceal epithelial neoplasms. Read More

    Recurrence Pattern and Lymph Node Metastasis of Adenocarcinoma at the Esophagogastric Junction.
    Ann Surg Oncol 2017 Aug 21. Epub 2017 Aug 21.
    Department of Surgery, Seoul National University College of Medicine, 101 Daehang-Ro, Jongno-gu, 110-744, Seoul, Korea.
    Background: The surgical approach for adenocarcinoma of the esophagogastric junction (AEJ) still is controversial despite revised tumor-node-metastasis (TNM) classification. This study aimed to evaluate the oncologic outcome of a routine transhiatal approach for AEJ in terms of recurrence and lymph node (LN) metastasis of AEJ.

    Methods: Recurrence patterns and LN metastasis of a single, primary AEJ (n = 463) treated by a surgical resection using a transhiatal approach without routine complete mediastinal LN dissection or routine splenectomy were analyzed respectively. Read More

    Outcomes for Women with Minimal-Volume Ductal Carcinoma In Situ Completely Excised at Core Biopsy.
    Ann Surg Oncol 2017 Aug 21. Epub 2017 Aug 21.
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Background: Overdiagnosis and overtreatment of ductal carcinoma in situ (DCIS) are concerns, especially for women with low-volume, screen-detected DCIS. This study aimed to evaluate the outcomes for such patients.

    Methods: Women who had minimal-volume DCIS (mDCIS, defined as DCIS diagnosed by core biopsy but with no residual disease on the surgical excision) treated with breast-conserving surgery from 1990 to 2011 were identified. Read More

    Incorporation of Treatment Response, Tumor Grade and Receptor Status Improves Staging Quality in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.
    Ann Surg Oncol 2017 Aug 21. Epub 2017 Aug 21.
    Department of Surgery, Mayo Clinic Rochester, Rochester, MN, USA.
    Background: Improved staging systems that better predict survival for breast cancer patients who receive neoadjuvant chemotherapy (NAC) by accounting for clinical pathological stage plus estrogen receptor (ER) and grade (CPS+EG) and ERBB2 status (Neo-Bioscore) have been proposed. We sought to evaluate the generalizability and performance of these staging systems in a national cohort.

    Methods: The National Cancer Database (2006-2012) was reviewed for patients with breast cancer who received NAC and survived ≥90 days after surgery. Read More

    Risk Factors for Lateral Neck Recurrence of N0/N1a Papillary Thyroid Cancer.
    Ann Surg Oncol 2017 Aug 18. Epub 2017 Aug 18.
    Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
    Background: Current guidelines advocate no prophylactic dissection of the lateral neck compartment for papillary thyroid carcinoma (PTC) without clinical evidence of lateral neck metastasis (cN1b). However, lateral neck recurrence can affect patient treatment outcomes and quality of life. Therefore, this study examined the risk factors for lateral neck recurrence after the definitive treatment of PTC without cN1b. Read More

    Association Between Patient Satisfaction and Short-Term Outcomes After Major Cancer Surgery.
    Ann Surg Oncol 2017 Aug 17. Epub 2017 Aug 17.
    Dow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, MI, USA.
    Objective: The aim of this study was to investigate whether patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, is associated with short-term outcomes after major cancer surgery.

    Materials And Methods: We first used national Medicare claims to identify patients who underwent a major extirpative cancer surgery from 2011 to 2013. Next, we used Hospital Compare data to assign the HCAHPS score to the hospital where the patient underwent surgery. Read More

    Adjunctive Breast-Specific Gamma Imaging for Detecting Cancer in Women with Calcifications at Mammography.
    Ann Surg Oncol 2017 Aug 17. Epub 2017 Aug 17.
    Department of Nuclear Medicine, Seoul Medical Center, Seoul, Korea.
    Background: Mammography detects calcium deposits sensitively, but the specificity for differentiating malignancy from benign calcifications is low. Thus, we investigated whether adjunctive breast-specific gamma imaging (BSGI) has incremental value for detecting cancer in women with suspicious calcifications detected by mammography, and compared BSGI with adjunctive ultrasonography (US).

    Methods: The medical records of women without a personal history of breast cancer who underwent mammography for breast evaluation from 2009 to 2014 were reviewed retrospectively. Read More

    Endoscopic Ultrasound as a Pretreatment Clinical Staging Tool for Gastric Cancer: Association with Pathology and Outcome.
    Ann Surg Oncol 2017 Aug 16. Epub 2017 Aug 16.
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Background: Endoscopic ultrasound (EUS) is a guideline-recommended diagnostic test to estimate pretreatment clinical stage in gastric cancer. The impact of EUS to discriminate long-term outcomes has not been established.

    Objectives: The objectives of our study were to (1) evaluate the association between EUS and pathologic stage; (2) evaluate the ability of EUS to predict disease-specific survival (DSS); and (3) determine how neoadjuvant chemotherapy (NCT) affects these relationships. Read More

    Transoral Resection of Human Papillomavirus (HPV)-Positive Squamous Cell Carcinoma of the Oropharynx: Outcomes with and Without Adjuvant Therapy.
    Ann Surg Oncol 2017 Aug 14. Epub 2017 Aug 14.
    Head and Neck Surgery Center of Florida, Florida Hospital Celebration Health and Florida Hospital Cancer Institute, Celebration, FL, USA.
    Background: With the rise of oropharyngeal squamous cell carcinoma associated with human papillomavirus (HPV), appropriate treatment strategies continue to be tailored toward minimizing treatment while preserving oncologic outcomes. This study aimed to compare the outcomes for those undergoing transoral resection with or without adjuvant therapy for HPV-related oropharyngeal carcinoma.

    Methods: A case-match cohort analysis was performed at two institutions on patients with HPV-related oropharyngeal squamous cell carcinoma. Read More

    Robotic Total Pelvic Exenteration: Video-Illustrated Technique.
    Ann Surg Oncol 2017 Oct 14;24(11):3422-3423. Epub 2017 Aug 14.
    Division of Surgical Oncology, Department of General Surgery, City of Hope National Cancer Center, Duarte, CA, USA.
    Background: Robotic-assisted total pelvic exenteration (TPE) can offer a minimally invasive approach to a major multi-organ operation.

    Methods: In this video, we summarize a stepwise approach to robotic TPE in a 70 year-old female Jehovah's witness with a history of cervical cancer post-chemoradiation and radical hysterectomy who experienced local recurrence at the vaginal cuff involving the rectum and bladder.

    Results: The patient was placed in the lithotomy position. Read More

    Hospitalization in the Year Preceding Major Oncologic Surgery Increases Risk for Adverse Postoperative Events.
    Ann Surg Oncol 2017 Aug 14. Epub 2017 Aug 14.
    Department of Surgery, Center for Surgery and Health Economics, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
    Background: Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes.

    Methods: Patients 18 years of age or older with stomach, pancreas, colon, or rectal cancer who underwent resection in California and New York (2008-2010) were included in the study. Read More

    Patients with Non-invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features are Unlikely to have Malignant Preoperative Cytology.
    Ann Surg Oncol 2017 Aug 11. Epub 2017 Aug 11.
    Department of Surgery, University of California, Davis Medical Center, Sacramento, CA, USA.
    Background: The newly termed tumor 'noninvasive follicular thyroid neoplasm with papillary-like nuclear features' (NIFTP) acts in an indolent manner and can likely be safely managed with a thyroid lobectomy. Preoperative fine-needle aspiration (FNA) is the cornerstone of surgical planning, but the ability of FNA to distinguish NIFTP from other variants of papillary thyroid carcinoma (PTC) has not been well-evaluated.

    Methods: A 9-year retrospective review of the preoperative cytology and surgical pathology of PTC patients who underwent a thyroidectomy at our tertiary referral center. Read More

    Safety and Efficacy of Isolated Limb Infusion Chemotherapy for Advanced Locoregional Melanoma in Elderly Patients: An Australian Multicenter Study.
    Ann Surg Oncol 2017 Aug 10. Epub 2017 Aug 10.
    Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia.
    Background: Isolated limb infusion (ILI) offers a minimally invasive treatment option for locally advanced extremity melanoma.

    Objective: The aim of the current study was to evaluate the safety and efficacy of ILI in elderly patients in an Australian multicenter setting.

    Methods: The results of 316 first ILI procedures, performed between 1992 and 2008 in five Australian institutions, were identified and analyzed, with the main focus on elderly patients (≥75 years of age). Read More

    Optimal Lymphadenectomy for Duodenal Adenocarcinoma: Does the Number Alone Matter?
    Ann Surg Oncol 2017 Aug 10. Epub 2017 Aug 10.
    Department of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
    Background: Duodenal adenocarcinoma (DA) is a rare disease, and the optimal extent of lymphadenectomy and the role of limited resection remain controversial.

    Objective: The aim of our study was to assess the pattern of regional lymph node spread of DA and to determine the optimal extent of resection.

    Methods: A total of 65 patients who underwent curative resection for DA at our institution from 1989 through 2015 were included in this study. Read More

    1 OF 175