31,336 results match your criteria Annals of surgery[Journal]


A Novel Immune Modulator for Patients With Necrotizing Soft Tissue Infections (NSTI): Results of a Multicenter, Phase 3 Randomized Controlled Trial of Reltecimod (AB 103).

Ann Surg 2020 Jul 8. Epub 2020 Jul 8.

University of Kentucky, Lexington, Kentucky.

Background And Objective: Reltecimod, a CD 28 T-lymphocyte receptor mimetic, inhibits T-cell stimulation by an array of bacterial pathogens. A previous phase 2 trial demonstrated improved resolution of organ dysfunction after NSTI. We hypothesized that early administration of reltecimod would improve outcome in severe NSTI. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004102DOI Listing

Robotic Assisted Living Donor Nephrectomies: A Safe Alternative to Laparoscopic Technique for Kidney Transplant Donation.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Illinois.

Objective: To review outcomes after laparoscopic, robotic-assisted living donor nephrectomy (RLDN) in the first, and largest series reported to date.

Summary Of Background Data: Introduction of minimal invasive, laparoscopic donor nephrectomy has increased live kidney donation, paving the way for further innovation to expand the donor pool with RLDN.

Methods: Retrospective chart review of 1084 consecutive RLDNs performed between 2000 and 2017. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004247DOI Listing

Diagnosing Pathologic Complete Response in the Breast After Neoadjuvant Systemic Treatment of Breast Cancer Patients by Minimal Invasive Biopsy: Oral Presentation at the San Antonio Breast Cancer Symposium on Friday, December 13, 2019, Program Number GS5-03.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Gynecology/Breast Unit, University Hospital Heidelberg, Heidelberg, Germany.

Objective: We evaluated the ability of minimally invasive, image-guided vacuum-assisted biopsy (VAB) to reliably diagnose a pathologic complete response in the breast (pCR-B).

Summary Background Data: Neoadjuvant systemic treatment (NST) elicits a pathologic complete response in up to 80% of women with breast cancer. In such cases, breast surgery, the gold standard for confirming pCR-B, may be considered overtreatment. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004246DOI Listing

Post-discharge Opioid Consumption After Minimally Invasive and Open Colectomy: Does Operative Approach Matter?

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, University of Michigan, Ann Arbor, Michigan.

Objective: To determine if patients consume less opioid after minimally invasive colectomy compared to open colectomy.

Background: Opioids are overprescribed after surgery, and surgeons are under increasing pressure to reduce postoperative opioid prescribing. In colorectal surgery, minimally invasive approaches are partly justified by reduced inpatient opioid use, but there are no studies comparing post-discharge opioid consumption between minimally invasive and open colectomy. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004240DOI Listing

A Novel Staging System for De Novo Metastatic Breast Cancer Refines Prognostic Estimates.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Objective: We aim to identify prognostic groups within a de novo metastatic cohort, incorporating both anatomic and biologic factors.

Background: Staging for breast cancer now includes anatomic and biologic factors, although the guidelines for stage IV disease do not account for how these factors may influence outcomes.

Methods: Adults with de novo metastatic breast cancer were selected from the National Cancer DataBase (2010-2013). Read More

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http://dx.doi.org/10.1097/SLA.0000000000004231DOI Listing

Transferability of Liver Transplantation Experience to Complex Liver Resection for Locally Advanced Hepatobiliary Malignancy - Lessons Learnt From 3 Decades of Single Center Experience.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

Objective: To study the impact of LT experience on the outcome of CLR for locally advanced hepatobiliary malignancy SUMMARY OF BACKGROUND DATA:: Despite evolution in LT knowledge and surgical techniques in the past decades, there is yet data to evaluate the significance of LT experience in performing CLR.

Methods: Postoperative outcome after CLR between 1995 and 2019 were reviewed and correlated with LT experience in a single center with both LT and CLR service. CLR was defined as hepatectomy with vasculobiliary reconstruction, or multivisceral resection, central bisectionectomy (S4/5/8), or associating liver partition and portal vein ligation for staged hepatectomy. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004227DOI Listing

Opioids After Surgery in the United States Versus the Rest of the World: The International Patterns of Opioid Prescribing (iPOP) Multicenter Study.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts.

Objective: The International Patterns of Opioid Prescribing study compares postoperative opioid prescribing patterns in the United States (US) versus the rest of the world.

Summary Of Background Data: The US is in the middle of an unprecedented opioid epidemic. Diversion of unused opioids contributes to the opioid epidemic. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004225DOI Listing

Utilization and Performance Benchmarking for Postoperative Imaging in Children With Complicated Appendicitis: Results From a Multicenter Collaborative Cohort Study.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA.

Objective: The aim of this study was to characterize hospital-level variation and establish diagnostic performance benchmarks for postoperative imaging in children with complicated appendicitis.

Summary Background Data: Wide variation in preoperative imaging in children with suspected appendicitis has been previously described. Variation in the use and accuracy of postoperative imaging to diagnose suspected organ space infection (OSI) following appendectomy has not been characterized. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004250DOI Listing

Multitasking and Time Pressure in the Operating Room: Impact on Surgeons' Brain Function.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Neuroergonomics and Perception Laboratory, Hamlyn Centre for Robotic Surgery, Imperial College London, London, UK.

Objective: To assess the impact of multitasking and time pressure on surgeons' brain function during laparoscopic suturing.

Summary Background Data: Recent neuroimaging evidence suggests that deterioration in surgical performance under time pressure is associated with deactivation of the prefrontal cortex (PFC), an area important for executive functions. However, the effect of multitasking on operator brain function remains unknown. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004208DOI Listing

Patterns of National Institutes of Health Grant Funding to Surgical Research and Scholarly Productivity in the United States.

Authors:
Gail E Besner

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Nationwide Children's Hospital, Columbus, Ohio.

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http://dx.doi.org/10.1097/SLA.0000000000004187DOI Listing

The Surgeon's Perceived Value of Patient-reported Outcome Measures (PROMs): An Exploratory Qualitative Study of 5 Different Surgical Subspecialties.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Massachusetts General Hospital Physician Organization, Boston, Massachusetts.

Objective: To understand the surgeon's perceived value of PROMs in 5 different surgical subspecialties.

Summary Of Background Data: PROMs are validated questionnaires that assess the symptoms, function, and quality of life from the patient's perspective. Despite the increasing support for use of PROMs in the literature, there is limited uptake amongst surgeons. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004253DOI Listing

Comment on "Impact of Oral Immunonutrition on Postoperative Morbidity in Digestive Oncologic Surgery: A Nation-wide Cohort Study".

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of General Surgery, Shanghai Clinical Nutrition Research Center, Zhongshan Hospital, Fudan University, Shanghai, China Department of General Surgery, Shanghai Clinical Nutrition Research Center, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1097/SLA.0000000000004249DOI Listing

Commentary on "The Evolution of Transplantation From Saving Lives to Fertility Treatment DUETS (Dallas UtErus Transplant Study)".

Authors:
Kim M Olthoff

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Perelman School of Medicine at the University of Pennsylvania, Penn Transplant Institute, Philadelphia, PA.

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http://dx.doi.org/10.1097/SLA.0000000000004194DOI Listing

Commentary on Quantifying Factors Essential to the Integrity of the Esophagogastric Junction During Anti-reflux Procedures.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1097/SLA.0000000000004195DOI Listing

Quantifying Performance Decline in the Operating Room Using fNIRS.

Authors:
Carla M Pugh

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Stanford Hospital and Clinics, Stanford, California.

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http://dx.doi.org/10.1097/SLA.0000000000004196DOI Listing

Commentary: Comparative Effectiveness Research in Pregnant Patients With Acute Cholecystitis - Challenges and Opportunities.

Authors:
Lillian S Kao

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

McGovern Medical School at University of Texas Health Science Center at Houston, Houston, Texas.

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http://dx.doi.org/10.1097/SLA.0000000000004197DOI Listing

Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Division of Hepatobiliary and Pancreatic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Objective: PDAC patients who undergo surgical resection and receive effective chemotherapy have the best chance of long-term survival. Unfortunately, we lack predictive biomarkers to guide optimal systemic treatment. Ex-vivo generation of PDO for pharmacotyping may serve as predictive biomarkers in PDAC. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004200DOI Listing

The Evolution of Transplantation From Saving Lives to Fertility Treatment: DUETS (Dallas UtErus Transplant Study).

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, Texas.

Objective: We report the results of the first 20 uterus transplants performed in our institution.

Summary Background Data: Uterus transplantation (UTx) aims at giving women affected by absolute uterine-factor infertility the possibility of carrying their own pregnancy. UTx has evolved from experimental to an established surgical procedure. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004199DOI Listing

Quantifying Factors Essential to the Integrity of the Esophagogastric Junction During Antireflux Procedures.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Division of Endocrine & Minimally Invasive Surgery, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.

Objective: To quantify the contribution of key steps in antireflux surgery on compliance of the EGJ.

Background: The lower esophageal sphincter and crural diaphragm constitute the intrinsic and extrinsic sphincters of the EGJ, respectively. Interventions to treat reflux attempt to restore the integrity of the EGJ. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004202DOI Listing

Long-term Prognosis After Elective AAA Repair is Poor in Women and Men: The Challenges Remain.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.

Objective: To evaluate the impact of changes in elective AAA management on life-expectancy of AAA patients.

Background: Over the past decades AAA repair underwent substantial changes, that is, the introduction of EVAR and implementation of intensified cardiovascular risk management. The question rises to what extent these changes improved longevity of AAA patients. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004182DOI Listing

Finding the "True" N0 Cohort: Technical Aspects of Near-infrared Sentinel Lymph Node Mapping in Non-small Cell Lung Cancer.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Objective: To examine technical-, patient-, tumor-, and treatment-related factors associated with NIR guided SLN identification.

Background: Missed nodal disease correlates with recurrence in early stage NSCLC. NIR-guided SLN mapping may improve staging and outcomes through identification of occult nodal disease. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004176DOI Listing

Adverse Biology in Adenocarcinoma of the Esophagus and Esophagogastric Junction Impacts Survival and Response to Neoadjuvant Therapy Independent of Anatomic Subtype.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, National Esophageal and Gastric Cancer Center, St. James's Hospital, Dublin, and Trinity College Dublin, Dublin, Ireland.

Objective: The aim of this study was to propose and test a novel adverse pathology classification in AEG.

Background: Recent scientific advances show genomic and molecular concordance across all AEG types, suggesting a rationale for a biologic classification. We tested a 3-dimension adverse pathology classification across the entire junction and per Siewert anatomic subtype. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004184DOI Listing

Response to the Letter to the Editor for "Clinical Importance of Mean Corpuscular Volume as a Prognostic Marker After Esophagectomy for Esophageal Cancer: A Retrospective Study".

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Chuoku, Kumamoto, Japan Division of Translational Research and Advanced Treatment Against Gastrointestinal Cancer, Kumamoto University, Chuoku, Kumamoto, Japan Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Chuoku, Kumamoto, Japan.

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http://dx.doi.org/10.1097/SLA.0000000000004128DOI Listing

Failure to Cure in Patients Undergoing Surgery for Esophageal Carcinoma: Hospital of Surgery Influences Prospects for Cure: A Nation-wide Cohort Study.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, Amsterdam UMC, AMC, Cancer Centre Amsterdam, University of Amsterdam, Amsterdam, the Netherlands.

Objective: This study aimed to describe failure to cure in terms of incidence, hospital variation, and as an outcome parameter for salvage esophagectomy.

Summary Background Data: Failure to cure is a composite outcome measure that could be used for hospital comparison in esophageal carcinoma care.

Methods: All patients registered in the Dutch Upper GI Cancer Audit who underwent potentially curative esophageal carcinoma surgery in 2011 to 2018, were included in this nationwide cohort study. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004178DOI Listing

Breast Implant-Associated Anaplastic Large Cell Lymphoma Incidence: Determining an Accurate Risk.

Authors:
Frances C Wright

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Sunnybrook Health Sciences Center, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada Quality and Knowledge Transfer Lead for Surgical Oncology, Ontario Health-Cancer Care Ontario, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/SLA.0000000000004177DOI Listing

Banded Versus Nonbanded Sleeve Gastrectomy: A Randomized Controlled Trial With 3 Years of Follow-up.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of General and Visceral Surgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Objective: The aim of this study was to compare silicone-banded sleeve gastrectomy (BSG) to nonbanded sleeve gastrectomy (SG) regarding weight loss, obesity-related comorbidities, and complications.

Summary Background Data: As a primary bariatric procedure, SG leads to excellent weight loss, yet weight regain is a relevant issue in mid- to long-term follow-up. Retrospective analyses suggest that banding a sleeve using a silicone ring may decrease weight regain and improve weight loss. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004174DOI Listing

The Impact of Radiotherapy on Patient-reported Outcomes of Immediate Implant-based Breast Reconstruction With and Without Mesh.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Population Health Sciences, Bristol Medical School, Clifton, Bristol, UK.

Objective: To explore the impact of PMRT on PROs of IBBR performed with and without mesh.

Summary Of Background Data: PMRT is increasingly given to improve breast cancer outcomes but can adversely impact complications after IBBR. Little; however, is known about the impact of PMRT on the PROs of IBBR, especially when mesh is used. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004245DOI Listing

Follicular Neoplasms of the Thyroid: Can They Be Observed?

Authors:
Herbert Chen

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1097/SLA.0000000000004127DOI Listing

Predicting the Outcome of Limb Revascularization in Patients With Lower-extremity Arterial Trauma: Development and External Validation of a Supervised Machine-learning Algorithm to Support Surgical Decisions.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Centre for Trauma Sciences, Queen Mary, University of London, London, UK.

Objectives: Estimating the likely success of limb revascularization in patients with lower-extremity arterial trauma is central to decisions between attempting limb salvage and amputation. However, the projected outcome is often unclear at the time these decisions need to be made, making them difficult and threatening sound judgement. The objective of this study was to develop and validate a prediction model that can quantify an individual patient's risk of failed revascularization. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004132DOI Listing

Risk Factors of Positive Resection Margin in Laparoscopic and Open Liver Surgery for Colorectal Liver Metastases: A New Perspective in the Perioperative Assessment: A European Multicenter Study.

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

Department of Hepatobiliary and Pancreatic Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

Objective: To assess the risk factors associated with R1 resection in patients undergoing OLS and LLS for CRLMs.

Background: The clinical impact of R1 resection in liver surgery for CRLMs has been continuously appraised, but R1 risk factors have not been clearly defined yet.

Methods: A cohort study of patients who underwent OLS and LLS for CRLMs in 9 European high-volume referral centers was performed. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004077DOI Listing

The Complexity of Neoadjuvant Therapy for Operable Pancreatic Cancer: Lessons Learned From SWOG S1505.

Authors:
Douglas B Evans

Ann Surg 2020 Jul 9. Epub 2020 Jul 9.

The LaBahn Pancreatic Cancer Program, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1097/SLA.0000000000004131DOI Listing

Clinical Presentation, Treatment, and Outcome of Parathyroid Carcinoma: Results of the NEKAR Retrospective International Multicenter Study.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany.

Objective: In this retrospective cohort study, we describe the clinical presentation and workup of parathyroid carcinoma (PC) and determine its clinical prognostic parameters. Primary outcome was recurrence free survival.

Summary Background Data: PC is an orphan malignancy for which diagnostic workup and treatment is not established. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004144DOI Listing

But we need to do more….

Authors:
Justin B Dimick

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

University of Michigan Health Systems, Ann Arbor, MI United States.

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http://dx.doi.org/10.1097/SLA.0000000000004264DOI Listing

Defining the "Tipping Point" to Success as a Surgeon-Scientist: An Analysis of Applicants and Awardees of the American College of Surgeons Jacobson Promising Investigator Award.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Surgical Research Committee, American College of Surgeons, Chicago, IL.

Background: Since 2005, the American College of Surgeons has administered the Jacobson Promising Investigator Award (JPIA), which recognizes surgeon-scientists at the "tipping point" of their research careers.

Objective: We retrospectively reviewed JPIA applicants to identify factors associated with selection for the award and future research success.

Methods: Profiles were reviewed for all applicants between 2008 and 2018, at the time of application and as of 2019. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004142DOI Listing

Actual Five-year Survival After Upfront Resection for Pancreatic Ductal Adenocarcinoma: Who Beats the Odds?

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Objective: To determine actual five-year survival (5YS) rates associated with a strategy of upfront surgery and adjuvant therapy in pancreatic ductal adenocarcinoma (PDAC).

Background: The rate of actual 5YS in PDAC remains controversial. Available data is restricted to cohorts acquired over several decades and series of resection after patient selection by neoadjuvant therapy. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004147DOI Listing

Colon Involvement in Necrotizing Pancreatitis: Incidence, Risk Factors, and Outcomes.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.

Objective: To investigate the incidence, risk factors, and outcomes of colon involvement in patients with necrotizing pancreatitis.

Summary/background Data: Necrotizing pancreatitis is characterized by a profound inflammatory response with local and systemic implications. Mesocolic involvement can compromise colonic blood supply leading to ischemic complications; however, few data exist regarding this problem. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004149DOI Listing

The Relationship Between Lymph Node Ratio and Survival Benefit With Adjuvant Chemotherapy in Node-positive Esophageal Adenocarcinoma.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Background: We hypothesized that the ratio of positive lymph nodes to total assessed lymph nodes (LNR) is an indicator of cancer burden in esophageal adenocarcinoma and may identify patients who may most benefit from AC.

Objective: The aim of this study was to discern whether there is a threshold LNR above which AC is associated with a survival benefit in this population.

Methods: The 2004-2015 National Cancer Database was queried for patients who underwent upfront, complete resection of pT1-4N1-3M0 esophageal adenocarcinoma. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004150DOI Listing

Benchmarking Accomplishments of Leaders in American Surgery and Justification for Enhancing Diversity and Inclusion.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, University of Alabama-Birmingham (UAB), Birmingham, Alabama.

Objective: To comprehensively assess the level of achievement and demographics of national surgical society presidents.

Background: Data on the accomplishments needed to rise to positions of national surgical leadership is scarce and merit alone does not always yield such opportunities. Recognizing the shortcomings of sex and ethnic diversity within academic surgical leadership, the American College of Surgeon (ACS), American Surgical Association (ASA), Association of Women Surgeons (AWS), and the Society of Black Academic Surgeons (SBAS) partnered to address these challenges by performing a comprehensive assessment of their presidents over the last 16 years. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004151DOI Listing

Ethics of Facial Transplantation: The Effect of Psychological Trauma Associated With Facial Disfigurement on Risk Acceptance and Decision Making.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Division of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, Canada.

Objective: This study examines and contrasts the effect of risk disclosure on risk acceptance and perceived changes in quality of life (QoL) among individuals with and without facial disfigurement.

Summary Of Background Data: Psychological distress has been previously shown to alter patients' perception of certain treatments. Due to the grave risks and complications of FT, it is important to understand whether the psychological trauma associated with facial disfigurement alters their perception of FT and its associated risks. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004156DOI Listing
July 2020
8.327 Impact Factor

Comment on: "Intraoperative 3D Hologram Support With Mixed Reality Techniques in Liver Surgery".

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

2nd Orthopaedic Department, School of Medicine, National and Kapodistrian University of Athens, "Konstantopoulio-Patission" Hospital, Nea Ionia, Greece Department of Anatomy, European University of Cyprus, Engomi Nicosia, Cyprus 2nd Orthopaedic Department School of Medicine, National and Kapodistrian University of Athens "Konstantopoulio-Patission" Hospital Nea Ionia, Greece Department of Anatomy, School of Medicine, National and Kapodistrian University of Athens Athens, Greece 2nd Orthopaedic Department School of Medicine, National and Kapodistrian University of Athens "Konstantopoulio-Patission" Hospital Nea Ionia, Greece.

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http://dx.doi.org/10.1097/SLA.0000000000004157DOI Listing

I Can't Breathe - Race, Violence and COVID-19.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/SLA.0000000000004256DOI Listing

Response to Comment on "Extended Molecular Profiling Improves Stratification and Prediction of Survival After Resection of Colorectal Liver Metastases".

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of General, Visceral and Transplantation Surgery, Universitätsmedizin Mainz Mainz, Germany Department of Pathology, Universitätsmedizin Mainz Mainz, Germany Department of Gastroenterology and Hepatology, Universitätsmedizin Mainz, Mainz, Germany Department of Pathology, Universita[Combining Diaeresis]tsmedizin Mainz, Mainz, Germany Department of General, Visceral and Transplantation Surgery, Universita[Combining Diaeresis]tsmedizin Mainz Mainz, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000004097DOI Listing

Women Surgeons' Perspectives on System-level Strategies to Address Interpersonal Workplace Conflict.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

University of Michigan, Center for Health Outcomes and Policy, Ann Arbor, Michigan.

Objective: We sought to gain a comprehensive understanding of the current methods for conflict resolution and the ways in which women surgeons would prefer workplace conflicts to be adjudicated.

Summary Of Background Data: Interprofessional workplace conflicts are poorly studied, particularly for women in surgery. These conflicts may negatively impact surgical team dynamic and be detrimental to patient safety. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004074DOI Listing

The IDEAL Reporting Guidelines: A Delphi Consensus Statement Stage specific recommendations for reporting the evaluation of surgical innovation.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

University of Oxford, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, UK.

Objective: The aim of this study was to define reporting standards for IDEAL format studies.

Background: The IDEAL Framework and Recommendations establish an integrated pathway for evaluation of new surgical techniques and complex therapeutic technologies. However guidance on implementation has been incomplete, and incorrect use is commonly seen. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004180DOI Listing

Global Overview of Response Rates in Patient and Health Care Professional Surveys in Surgery: A Systematic Review.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, University Medical Centre Groningen, University of Groningen, The Netherlands.

Objective: Identify key demographic factors and modes of follow-up in surgical survey response.

Summary Background Data: Surveys are widely used in surgery to assess patient and procedural outcomes, but response rates vary widely which compromises study quality. Currently there is no consensus as to what the average response rate is and which factors are associated with higher response rates. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004078DOI Listing

Noninvasive Discrimination of Low and High-risk Pancreatic Intraductal Papillary Mucinous Neoplasms.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Objective: To propose a noninvasive diagnostic approach, which allows reliable distinction between low- and high-risk pancreatic intraductal papillary mucinous neoplasms (IPMNs).

Background: IPMNs are identifiable precursor lesions of pancreatic cancer, of which surgical resection is warranted prior to the development of invasive carcinoma, but low-grade IPMNs should not be unnecessarily resected. However, diagnostic tools that preoperatively enable accurate risk stratification of IPMNs are missing. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004066DOI Listing

Invited Commentary on: Results of a Multicenter, Phase 3 Randomized Controlled Trial of Reltecimod.

Authors:
Avery B Nathens

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/SLA.0000000000004135DOI Listing

A Combination of Biochemical and Pathological Parameters Improves Prediction of Postresection Survival After Preoperative Chemotherapy in Pancreatic Cancer: The PANAMA-score.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Objective: To build a prognostic score for patients with primary chemotherapy undergoing surgery for pancreatic cancer based on pathological parameters and preoperative Carbohydrate antigen 19-9 (CA19-9) levels.

Background: Prognostic stratification after primary chemotherapy for pancreatic cancer is challenging and prediction models, such as the AJCC staging system, lack validation in the setting of preoperative chemotherapy.

Methods: Patients with primary chemotherapy resected at the Massachusetts General Hospital between 2007 and 2017 were analyzed. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004143DOI Listing