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    30096 results match your criteria Annals of surgery[Journal]

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    Anatomical Resections Improve Survival Following Lung Metastasectomy of Colorectal Cancer Harboring KRAS Mutations.
    Ann Surg 2018 May 17. Epub 2018 May 17.
    Department of Thoracic and Upper Gastrointestinal Surgery, McGill University Health Center, Montreal. Canada.
    Objective: The aim of this study was to evaluate the benefit of anatomical resection (AR) in lung metastasectomy (LM) of colorectal cancer (CRC) harboring KRAS mutations SUMMARY BACKGROUND DATA:: KRAS mutations are related to high aggressiveness in the lung metastasis of CRC. It is unknown whether AR can lead to better outcomes than can non-AR (NAR) in KRAS patients.

    Methods: We retrospectively reviewed the data from 574 consecutive patients who underwent a LM for CRC. Read More

    Identification of the Critical Nontechnical Skills for Surgeons Needed for High Performance in a Variable-resource Context (NOTSS-VRC).
    Ann Surg 2018 May 17. Epub 2018 May 17.
    Center for Surgery and Public Health: Harvard Medical School, Harvard T.H. Chan School of Public Health, Boston, MA.
    Objective: To identify the critical nontechnical skills (NTS) required for high performance in variable-resource contexts (VRC).

    Background: As surgical training and capacity increase in low- and middle-income countries (LMICs), new strategies for improving surgical education and care in these settings are required. NTS are critical for high performance in surgery around the world. Read More

    Preperitoneal or Subcutaneous Wound Catheters as Alternative for Epidural Analgesia in Abdominal Surgery: A Systematic Review and Meta-analysis.
    Ann Surg 2018 May 17. Epub 2018 May 17.
    Department of Surgery, Cancer Center Amsterdam, Academic Medical Center, University of Amsterdam, The Netherlands.
    Objective: To assess whether the location of wound catheters (ie, preperitoneal vs. subcutaneous) impacts outcomes, when compared with alternatives such as epidural analgesia.

    Background: Continuous wound infiltration is an alternative for epidural analgesia in abdominal surgery but studies have shown conflicting results. Read More

    Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-Year Single-Center Experience.
    Ann Surg 2018 May 17. Epub 2018 May 17.
    Comprehensive Transplant Institute, Departments of Medicine and Surgery, University of Alabama at Birmingham, Birmingham, AL.
    Objective: To examine the largest single-center experience of simultaneous kidney/pancreas transplantation (SPK) transplantation among African-Americans (AAs).

    Background: Current dogma suggests that AAs have worse survival following SPK than white recipients. We hypothesize that this national trend may not be ubiquitous. Read More

    Percutaneous Stone Removal.
    Ann Surg 2018 May 16. Epub 2018 May 16.
    Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI Inova Alexandria Hospital, Cardiovascular and Interventional Radiology, Alexandria, VA Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI.

    Comments on "Alternative Fistula Risk Score for Pancreatoduodenectomy (a-FRS) Design and International External Validation".
    Ann Surg 2018 May 16. Epub 2018 May 16.
    AP-HP, Department of Hepato-Pancreato-Biliary and Endocrine Surgery, Hôpital Cochin, Paris, France Université Paris Descartes, Paris, France Université Paris Diderot, Paris, France AP-HP, Department of Pancreatology-Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon, Clichy, France Université Paris Diderot, Paris, France AP-HP, Department of Hepato-Pancreato-Biliary Surgery-Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon, Clichy, France.

    Early Impact of Medicare Accountable Care Organizations on Inpatient Surgical Spending.
    Ann Surg 2018 May 16. Epub 2018 May 16.
    Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI.
    Objective: To evaluate whether hospital participation in accountable care organizations (ACOs) is associated with reduced Medicare spending for inpatient surgery.

    Background: ACOs have proliferated rapidly and now cover more than 32 million Americans. Medicare Shared Savings Program (MSSP) ACOs have shown modest success in reducing medical spending. Read More

    Comparing Short-term and Oncologic Outcomes of Minimally Invasive Versus Open Pancreaticoduodenectomy Across Low and High Volume Centers.
    Ann Surg 2018 May 16. Epub 2018 May 16.
    Department of Surgery, University of Colorado, Aurora, CO.
    Objective: To compare short-term and oncologic outcomes of patients with cancer who underwent open pancreaticoduodenectomy (OPD) versus minimally invasive pancreaticoduodenectomy (MIPD) using the National Cancer Database.

    Summary Background Data: MIPD, including laparoscopic and robotic approaches, has continued to gain acceptance despite prior reports of increased short-term mortality when compared with OPD.

    Methods: Patients with pancreatic cancer diagnosed from 2010 to 2015 undergoing curative intent resection were selected from the National Cancer Database. Read More

    Detection of Deteriorating Patients on Surgical Wards Outside the ICU by an Automated MEWS-Based Early Warning System With Paging Functionality.
    Ann Surg 2018 May 16. Epub 2018 May 16.
    Department of Visceral, Thoracic, and Vascular Surgery, Medizinische Fakultät an der TU-Dresden, Germany.
    Background: The establishment of early warning systems in hospitals was strongly recommended in recent guidelines to detect deteriorating patients early and direct them to adequate care. Upon reaching predefined trigger criteria, Medical Emergency Teams (MET) should be notified and directed to these patients. The present study analyses the effect of introducing an automated multiparameter early warning score (MEWS)-based early warning system with paging functionality on 2 wards hosting patients recovering from highly complex surgical interventions. Read More

    A Succinct Critical Appraisal of Indications to Transanal Total Mesorectal Excision.
    Ann Surg 2018 May 14. Epub 2018 May 14.
    Division of Colorectal Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY Division of Colorectal Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY Division of Colorectal Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY.

    Oncological and Survival Outcomes in Watch and Wait Patients With a Clinical Complete Response After Neoadjuvant Chemoradiotherapy for Rectal Cancer: A Systematic Review and Pooled Analysis.
    Ann Surg 2018 May 9. Epub 2018 May 9.
    Basingstoke and North Hampshire Hospital. Hampshire, UK.
    Objective: The aim of this study was to evaluate the oncological and survival outcomes of a Watch and Wait policy in rectal cancer after a clinical complete response (cCR) following neoadjuvant chemoradiotherapy.

    Background: The detection of a cCR after neoadjuvant treatment may facilitate a nonoperative approach in selected patients. However, the long-term safety of this strategy remains to be validated. Read More

    Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II).
    Ann Surg 2018 May 9. Epub 2018 May 9.
    Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Scandinavian Surgical Outcomes Research Group, Sahlgrenska University, Hospital/Östra, Gothenburg, Sweden.
    Objective: The aim of this study was to evaluate the risk of bowel obstruction, incisional, and parastomal hernia following laparoscopic versus open surgery for rectal cancer.

    Summary Background Data: Laparoscopic surgery for rectal cancer has been adopted worldwide, after trials reported similar oncological outcomes compared with open surgery. Little is known about long-term morbidity, including bowel obstruction, incisional, and parastomal hernia following surgery. Read More

    Resection of the Primary Gastrointestinal Neuroendocrine Tumor Improves Survival with or without Liver Treatment.
    Ann Surg 2018 May 9. Epub 2018 May 9.
    Department of Surgery, City of Hope National Medical Center, Duarte, CA.
    Objective: The aim of this study was to determine outcomes of primary tumor resection in metastatic neuroendocrine tumors across all primary tumor sites.

    Background: Primary tumor resection (PTR) may offer a survival benefit in metastatic gastrointestinal neuroendocrine tumors (GI-NETs); however, few studies have examined the effect of primary site and grade on resection and survival.

    Methods: This is a retrospective study of patients with metastatic GI-NETs at presentation between 2005 and 2011 using the California Cancer Registry (CCR) dataset merged with California Office of Statewide Health Planning and Development (OSHPD) inpatient longitudinal database. Read More

    Prophylactic Mesh for the Prevention of Parastomal Hernias: Need for a Deep Dive.
    Ann Surg 2018 May 8. Epub 2018 May 8.
    Department of Surgical and Perioperative Sciences, Umeå University, Sweden, Department of Surgery, Sunderby Hospital, Sweden, Sunderby Hosptial, SWEDEN, Luleå Department of Surgical and Perioperative Sciences, Umeå University Department of Surgical and Perioperative Sciences, Umeå University, Departement of Surgery, Sunderby Hospital Departement of Imaging and Physiology, Karolinska University Hospital Department of Surgical and Perioperative Sciences, Umeå University Department of Surgical and Perioperative Sciences, Umeå University, Sunderby Research Unit.

    Should We Evaluate Liver Resection Difficulty by Separating Laparoscopic From Open Approaches?
    Ann Surg 2018 May 8. Epub 2018 May 8.
    Department of Digestive Surgery, Institut Mutualiste Montsouris, Paris, France Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Department of Digestive Surgery, Institut Mutualiste Montsouris, Paris, France National Center for Global Health and Medicine, Tokyo, Japan Department of Digestive Surgery, Institut Mutualiste Montsouris, Paris, France.

    Impact of Dexmedetomidine on Long-term Outcomes After Noncardiac Surgery in Elderly: 3-Year Follow-up of a Randomized Controlled Trial.
    Ann Surg 2018 May 8. Epub 2018 May 8.
    Section of Anaesthetics, Pain Management and Intensive Care, Department of Surgery and Cancer, Imperial College London, Chelsea and Westminster Hospital, London, UK.
    Objectives: The aim was to compare the long-term outcomes of low-dose dexmedetomidine versus placebo in a randomized controlled trial (ChiCTR-TRC-10000802).

    Background: Low-dose dexmedetomidine infusion decreased delirium occurrence within 1 week after surgery in elderly admitted to the intensive care unit (ICU) after noncardiac surgery, but the long-term outcome of this intervention is unknown.

    Methods: Patients or their family members were telephone-interviewed for a 3-year follow-up data collection of survival, cognitive function assessed with the modified Telephone Interview for Cognitive Status, and quality of life evaluated with the World Health Organization Quality of Life. Read More

    Pursuing Excellence: The Power of Selection Science to Provide Meaningful Data and Enhance Efficiency in Selecting Surgical Trainees.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    SurgWise Consulting, Houston, TX.
    Introduction: As current screening methods for selecting surgical trainees are receiving increasing scrutiny, development of a more efficient and effective selection system is needed. We describe the process of creating an evidence-based selection system and examine its impact on screening efficiency, faculty perceptions, and improving representation of underrepresented minorities.

    Methods: The program partnered with an expert in organizational science to identify fellowship position requirements and associated competencies. Read More

    Microsatellite Instability and Programmed Cell Death-Ligand 1 Expression in Stage II/III Gastric Cancer: Post Hoc Analysis of the CLASSIC Randomized Controlled study.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Department of Surgery, Yonsei University Health System, Seoul, South Korea.
    Objective: We investigated microsatellite instability (MSI) status and programed cell death ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to chemotherapy for stage II/III gastric cancer.

    Background: The clinical implications of MSI status and PD-L1 expression in gastric cancer have not been well-elucidated.

    Methods: Tumor specimens and clinical information were collected from patients enrolled in the CLASSIC trial-a randomized controlled study of capecitabine plus oxaliplatin-based adjuvant chemotherapy. Read More

    10th Anniversary of ALPPS-Lessons Learned and quo Vadis.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Swiss HPB and Transplantation Center, Department of Surgery, University Hospital Zurich, Zurich, Switzerland.
    Objective: Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) has been tested in various indications and clinical scenarios, leading to steady improvements in safety. This report presents the current status of ALPPS.

    Summary Background Data: ALPPS offers improved resectability, but drawbacks are regularly pointed out regarding safety and oncologic benefits. Read More

    Perfect Registration Leads to Imperfect Performance: A Randomized Trial of Multimodal Intraoperative Image Guidance.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Department of Surgery and Cancer, Imperial College London, London, UK.
    Objective: To compare surgical safety and efficiency of 2 image guidance modalities, perfect augmented reality (AR) and side-by-side unregistered image guidance (IG), against a no guidance control (NG), when performing a simulated laparoscopic cholecystectomy (LC).

    Background: Image guidance using AR offers the potential to improve understanding of subsurface anatomy, with positive ramifications for surgical safety and efficiency. No intra-abdominal study has demonstrated any advantage for the technology. Read More

    Short-term Outcomes of Ambulatory Colectomy for 157 Consecutive Patients.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Digestive and Endocrine Surgery, Hopital Privé de l'Estuaire, Le Havre, France.
    Objective: To evaluate short-term outcomes of laparoscopic colectomy for selected consecutive patients in an ambulatory setting at two institutions.

    Background: Several studies showed that an enhanced recovery protocol for colorectal surgery reduces postoperative morbidity and mortality, and shortens the length of hospital stay. The development of such a program has allowed us to gradually reduce the length of stay for colorectal surgery, until ambulatory management. Read More

    Metabolic Tumor Volume Change Predicts Long-term Survival and Histological Response to Preoperative Chemotherapy in Locally Advanced Esophageal Cancer.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.
    Objective: Here, we assess the ability of metabolic tumor volume (MTV) as measured by F-fluorodeoxyglucose-positron emission tomography/computed tomography (F-FDG PET/CT) to evaluate neoadjuvant chemotherapy response for patients with locally advanced esophageal cancer (EC).

    Background: Optimal methods to evaluate treatment response for EC patients have not yet been established. Although previous studies have reported the value of standardized uptake value (SUV), the accuracy of predicting histological response or long-term survival in EC is limited. Read More

    Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.
    Ann Surg 2018 May 1. Epub 2018 May 1.
    Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
    Objective: To investigate the effects of different types of surgery on breast cancer prognosis in germline BRCA1/BRCA2 mutation carriers compared with noncarriers.

    Summary Of Background Data: Although breast-conserving therapy (breast-conserving surgery followed by radiotherapy) has been associated with more local recurrences than mastectomy, no differences in overall survival have been found in randomized trials performed in the general breast cancer population. Whether breast-conservation can be safely offered to BRCA1/2 mutation carriers is debatable. Read More

    Prophylactic Mesh for the Prevention of Parastomal Hernias: Need for a Deep Dive.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON Department of Surgery, St. Michael's Hospital, Toronto, ON Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON.

    Modified Blumgart Mattress Suture Versus Conventional Interrupted Suture in Pancreaticojejunostomy During Pancreaticoduodenectomy: Randomized Controlled Trial.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
    Objective: This study used a randomized controlled trial (RCT) to evaluate whether mattress suture of pancreatic parenchyma and the seromuscular layer of jejunum (modified Blumgart method) during pancreaticojejunostomy (PJ) decreases the incidence of clinically relevant postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD).

    Background: Several studies reported that mattress suture of Blumgart anastomosis in PJ could reduce POPF rate. This, however, is the first RCT. Read More

    Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.
    Objective: To report 1-year results from a 5-year mandated study.

    Summary Background Data: In 2012, the United States Food and Drug Administration approved magnetic sphincter augmentation (MSA) with the LINX Reflux Management System (Torax Medical, Shoreview, MN), a novel device for the surgical treatment of gastroesophageal reflux disease (GERD). Continued assessment of safety and effectiveness has been monitored in a Post Approval Study. Read More

    Impact of Breast Surgery in Primary Metastasized Breast Cancer: Outcomes of the Prospective Randomized Phase III ABCSG-28 POSYTIVE Trial.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Department of Surgery, Medical University, Vienna, Austria.
    Background: Conflicting evidence exists regarding the value of surgical resection of the primary in stage IV breast cancer patients.

    Objective: The prospective randomized phase III ABCSG-28 POSYTIVE trial evaluated median survival comparing primary surgery followed by systemic therapy to primary systemic therapy in de novo stage IV breast cancer.

    Methods: Between 2011 and 2015, 90 previously untreated stage IV breast cancer patients were randomly assigned to surgical resection of the primary tumor followed by systemic therapy (Arm A) or primary systemic therapy (Arm B) in Austria. Read More

    The Challenge of Measuring Surgeon Spending for Payment Policies.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI.
    Objective: Our objective was to understand the reliability of profiling surgeons on average health care spending.

    Summary Of Background Data: Under its Merit-based Incentive Payment System (MIPS), Medicare will measure surgeon spending and tie performance to payments. Although the intent of this cost-profiling is to reward low-cost surgeons, it is unknown whether surgeons can be accurately distinguished from their peers. Read More

    A Statistical Model-driven Surgical Case Scheduling System Improves Multiple Measures of Operative Suite Efficiency: Findings From a Single-center, Randomized Controlled Trial.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
    Objective: We sought to determine whether a data-driven scheduling approach improves Operative Suite (OS) efficiency.

    Background: Although efficient use of the OS is a critical determinant of access to health care services, OS scheduling methodologies are simplistic and do not account for all the available characteristics of individual surgical cases.

    Methods: We randomly scheduled cases in a single OS by predicting their length using either the historical mean (HM) duration of the most recent 4 years; or a regression modeling (RM) system that accounted for operative and patient characteristics. Read More

    No Surgical Innovation Without Evaluation: Evolution and Further Development of the IDEAL Framework and Recommendations.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
    Objective: To update, clarify, and extend IDEAL concepts and recommendations.

    Background: New surgical procedures, devices, and other complex interventions need robust evaluation for safety, efficacy, and effectiveness. Unlike new medicines, there is no internationally agreed evaluation pathway for generating and analyzing data throughout the life cycle of surgical innovations. Read More

    Long-term Outcomes of Laparoscopic Versus Open Surgery for Clinical Stage II/III Gastric Cancer: A Multicenter Cohort Study in Japan (LOC-A Study).
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Department of Preventive Medicine and Public Health, Biostatistics at Center for Clinical Research, Keio University School of Medicine, Tokyo, Japan.
    Objective: A large-scale multicenter historical cohort study was conducted to investigate the efficacy of laparoscopic gastrectomy (LG) in comparison to open gastrectomy (OG) for locally advanced gastric cancer.

    Background: LG is now practiced widely, but its applicability for advanced gastric cancer is still controversial. As oncologic outcomes of randomized trials are still pending, there is an urgent need for information that would be relevant to current practice. Read More

    Quality Versus Quantity: The Potential Impact of Public Reporting of Hospital Safety for Complex Cancer Surgery.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Cancer Outcomes, Public Policy, and Effectiveness Research Center, Yale School of Medicine, New Haven, CT.
    Objective: To estimate the potential mortality reduction if patients chose the safest hospitals for complex cancer surgery.

    Background: Mortality after complex oncologic surgery is highly variable across hospitals, and directing patients away from unsafe hospitals could potentially improve survivorship. Hospital quality measures are becoming increasingly accessible at a time when patients are more engaged in choosing providers. Read More

    Potential Impact of "Take the Volume Pledge" on Access and Outcomes for Gastrointestinal Cancer Surgery.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
    Objective: To quantify the number of US hospitals that would meet "Take the Volume Pledge" (TVP) volume thresholds and compare outcomes at hospitals meeting and not meeting TVP thresholds.

    Summary Background Data: TVP aims to regionalize complex cancer resections to hospitals meeting established annual average volume thresholds. There is little data describing the potential impact on patient access if this initiative were broadly implemented or the relationship between these volume thresholds and quality of oncologic care. Read More

    Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Colorado Pulmonary-Alcohol Research Consotrium (CoPARC), University of Colorado School of Medicine, Aurora, CO.
    Objective: To derive and validate a prediction model for the development of ARDS in burn-injured patients.

    Summary Background Data: Burn injury carries the highest incidence of acute respiratory distress syndrome (ARDS) among all predisposing conditions, but few studies exist on risk factors in these patients. Studies employing biomarkers and clinical risk factors for predicting ARDS mortality have recently been examined but none exist for onset of ARDS nor in patients with burn injury. Read More

    Relationship Between Sarcopenic Obesity and Outcomes of Hepatectomy for Hepatocellular Carcinoma.
    Ann Surg 2018 Apr 24. Epub 2018 Apr 24.
    Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China Department of Clinical Medicine, Second Military Medical University, Shanghai 200433, China Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China.

    Surgery, Complications, and Quality of Life: A Longitudinal Cohort Study Exploring the Role of Psychosocial Factors.
    Ann Surg 2018 Apr 19. Epub 2018 Apr 19.
    Institute of Global Health Innovation, Imperial College London, London, UK.
    Objective: To determine whether psychosocial factors moderate the relationship between surgical complications and quality of life (QoL).

    Background: Patients who experience surgical complications have significantly worse postoperative QoL than patients with an uncomplicated recovery. Psychosocial factors, such as coping style and level of social support influence how people deal with stressful events, but it is unclear whether they affect QoL following a surgical complication. Read More

    Determinants of Severity in Acute Pancreatitis: A Nation-wide Multicenter Prospective Cohort Study.
    Ann Surg 2018 Apr 18. Epub 2018 Apr 18.
    Department of Gastroenterology, Alicante University General Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain.
    Objective: The aim of this study was to compare and validate the different classifications of severity in acute pancreatitis (AP) and to investigate which characteristics of the disease are associated with worse outcomes.

    Summary Of Background Data: AP is a heterogeneous disease, ranging from uneventful cases to patients with considerable morbidity and high mortality rates. Severity classifications based on legitimate determinants of severity are important to correctly describe the course of disease. Read More

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