462 results match your criteria Annals of palliative medicine[Journal]


The experiences of suffering of end-stage renal failure patients in Malaysia: a thematic analysis.

Ann Palliat Med 2019 Apr 1. Epub 2019 Apr 1.

Unit of Palliative Medicine, Faculty of Medicine, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.

Background: The population of end-stage renal failure (ESRF) receiving dialysis treatment is increasing worldwide. For most patients with ESRF, dialysis can extend their life. However, treatment can be demanding and time-consuming. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.04DOI Listing

Benzodiazepines and/or neuroleptics for the treatment of delirium in palliative care?-a critical appraisal of recent randomized controlled trials.

Ann Palliat Med 2019 Mar 26. Epub 2019 Mar 26.

Department of Geriatric Psychiatry, University Hospital of Psychiatry, Zurich, Switzerland; Department of Geriatrics and Aging Research, Department of Radiation Oncology, Competence Center Palliative Care, University Hospital Zurich, Zurich, Switzerland.

Delirium is a frequent condition in patients in a palliative care situation and most often associated with substantial burden or even danger for the persons concerned as well as caregivers and health-care-professionals. Despite the lack of randomized-controlled-trials (RCTs) benzodiazepines and neuroleptic agents are used extensively in palliative care for the pharmacological management of delirium. A focused review for RCTs assessing pharmacotherapy with benzodiazepines and neuroleptics for the treatment of delirium in patients treated in a palliative care or hospice setting published in 2017 was performed in PubMed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.06DOI Listing
March 2019
1 Read

"I want to die in my sleep"-how people think about death, choice, and control: findings from a Massive Open Online Course.

Ann Palliat Med 2019 Mar 28. Epub 2019 Mar 28.

Palliative and Supportive Services, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia.

Background: Complex social and ethical debates about voluntary assisted dying (euthanasia), palliative care, and advance care planning are presently being worked through in many developed countries, and the policy implications of these discussions for palliative care are potentially very significant. However, community attitudes to death and dying are complex, multilayered, and contain many mixed messages.

Methods: Participants posted comments in a Massive Open Online Course (MOOC) on death and dying, entitled Dying2Learn. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.07DOI Listing

Palliative care education for oncologists: how are we doing?

Ann Palliat Med 2019 Mar 28. Epub 2019 Mar 28.

Division of Surgical Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.05DOI Listing

Communication skill frameworks: applications in radiation oncology.

Ann Palliat Med 2019 Mar 25. Epub 2019 Mar 25.

Departments of Radiation Oncology and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Communication is an important part of high-quality care at every step. Communication skills can be learned, practiced, and improved. In this review, we outline the basic frameworks for communication skills training, describe their components, and demonstrate their utility in the context of vignettes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.03DOI Listing
March 2019
1 Read

Palliative radiotherapy: history, recent advances, and future directions.

Authors:
Stephen T Lutz

Ann Palliat Med 2019 Mar 15. Epub 2019 Mar 15.

Eastern Woods Radiation Oncology, Blanchard Valley Health Organization, Findlay, OH, USA.

Radiotherapy has been used to palliate cancer symptoms since shortly after the time that X rays were discovered late in the 1800's. The 20th century witnessed improvements in treatment planning and delivery that permitted radiotherapy to serve as a successful, timely, and cost-efficient palliative intervention. Palliative radiation oncology has risen to the level of its own subspecialty, as evidenced by the formation of palliative radiation oncology clinical services and dedicated palliative radiotherapy guidelines, while additional changes have begun to alter the very definition and goals of palliative radiotherapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.02DOI Listing
March 2019
1 Read

Validation of Modified Breast Graded Prognostic Assessment for breast cancer patients with brain metastases: extra-cranial disease progression is an independent risk factor.

Ann Palliat Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Radiation Oncology, National Cancer Centre Singapore, Singapore.

Background: Breast cancer (BC) patients with brain metastases (BM) are heterogeneous with markedly variable survival. The Breast Graded Prognostic Assessment (B-GPA) and Modified B-GPA (mB-GPA) have been proposed as useful tools for stratifying survival in this population. However, extra-cranial disease progression, a clinically important variable, is not incorporated into the final model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.05DOI Listing

Loss of relationship: a qualitative study of families and healthcare providers after patient death and home-based palliative care ends.

Ann Palliat Med 2019 Apr 1. Epub 2019 Apr 1.

Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada; Temmy Latner Centre for Palliative Care, Mount Sinai Hospital, Toronto, ON, Canada.

Background: Home-based palliative care is care of the patient in their home, while doctors and other healthcare providers (HCPs) make visits as required. Family involvement naturally cultivates a relationship between HCPs and the family. Once the patient dies and home-based palliative care ends, this relationship is abruptly terminated, which may be challenging to both the family and the HCPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.03.01DOI Listing
April 2019
1 Read

Perceived knowledge of palliative care among immigrants to the United States: a secondary data analysis from the Health Information National Trends Survey.

Ann Palliat Med 2019 Mar 13. Epub 2019 Mar 13.

Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, Minnesota, USA.

Background: Immigrants to North America receive more interventions at end of life potentially due to knowledge gaps. The primary objective of this study was to measure and describe levels of perceived knowledge about palliative care among immigrants to the United States (US) compared to those born in the US. Our secondary objective was to identify trusted sources for seeking information about palliative care among immigrants and compare these trusted sources with those born in the US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.06DOI Listing
March 2019
1 Read

Early palliative care and quality of life of advanced cancer patients-a multicenter randomized clinical trial.

Ann Palliat Med 2019 Mar 14. Epub 2019 Mar 14.

Research and Innovation Unit, University Hospital, Parma, Italy.

Background: To compare quality of life (QoL) of patients receiving early palliative care (EPC) vs. standard oncologic care (SOC).

Methods: Pragmatic, multicenter, randomized trial at five University and Community Hospital Cancer Centers in Northern Italy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.07DOI Listing
March 2019
3 Reads

Brain metastases: costs for care need to be spend more effectively!

Authors:
Pieter E Postmus

Ann Palliat Med 2019 Mar 1. Epub 2019 Mar 1.

Department of Pulmonary Diseases, Leiden University Medical Centre, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.04DOI Listing
March 2019
1 Read

Palliative radiation oncology programs: design, build, succeed!

Ann Palliat Med 2019 Mar 11. Epub 2019 Mar 11.

Department of Radiation Oncology, Medical College of Wisconsin, Wauwatosa, WI, USA.

The palliation of symptoms caused by advanced cancer is one of the most common indications for radiation therapy. Radiation therapy is an efficient and effective treatment for the palliation of pain, bleeding, obstruction, compression of nerves or the spinal cord and other local symptoms caused by tumors. The general principles of palliative radiation therapy are to use the shortest course of palliative radiation therapy needed to achieve the desired goal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.09DOI Listing
March 2019
1 Read

Global palliative radiotherapy: a framework to improve access in resource-constrained settings.

Ann Palliat Med 2019 Feb 23. Epub 2019 Feb 23.

Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario,Canada; Department of Radiation Oncology, University of Toronto, Ontario, Canada.

Radiotherapy is an essential component of cancer therapy. Lack of access to radiotherapy in less-developed countries prevents its use for both cure and symptom relief, resulting in a significant disparity in patient suffering. Several recent initiatives have highlighted the need for expanded access to both palliative medicine and radiotherapy globally. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.02DOI Listing
February 2019
2 Reads

Erratum to cannabis in palliative care: current challenges and practical recommendations.

Ann Palliat Med 2019 Feb 13. Epub 2019 Feb 13.

Department of Oncology, McGill University, Montreal, Canada; Clinique Santé Cannabis, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.06DOI Listing
February 2019
5 Reads

Radiation oncology resident education in palliative care.

Ann Palliat Med 2019 Feb 18. Epub 2019 Feb 18.

Department of Radiation Oncology, University of California Irvine, Orange, CA, USA; Department of Radiation Oncology, Long Beach Memorial Medical Center, Long Beach, CA, USA.

Palliative and supportive care education for radiation oncologists in training is essential to deliver comprehensive care to patients. Surveys on palliative care education among radiation oncology program directors and residents demonstrate a disparity in formal teaching and didactics. Integration of formal didactics, communications skills programs, and teaching modules are being piloted at academic centers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.07DOI Listing
February 2019
2 Reads

Society for Palliative Radiation Oncology: report from the Fifth Annual Meeting (2018).

Ann Palliat Med 2019 Feb;8(Suppl 1):S61-S63

New York Proton Center, New York, NY 10035, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.01DOI Listing
February 2019

Clinical parameters of wound healing in patients with advanced illness.

Ann Palliat Med 2019 Feb;8(Suppl 1):S5-S14

Palliative Medical Unit, Grantham Hospital, Aberdeen, Hong Kong, China.

Background: Pressure injury is a common clinical parameter of patient care outcome. Various risk factors increase the risk of palliative care patients to pressure injuries and difficult wound healing. Healthcare professionals are aware that wound healing is difficult, but they still focus on this process instead of providing the needs of patients with unhealed wounds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.05DOI Listing
February 2019
1 Read

The importance of nurses in the care of and research advancements for patients with advanced diseases.

Authors:
Charles B Simone

Ann Palliat Med 2019 Feb;8(Suppl 1):S1-S2

New York Proton Center, New York, NY 10035, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.04DOI Listing
February 2019

Cancer cachexia: definitions, outcomes, and treatments.

Authors:
Charles B Simone

Ann Palliat Med 2019 Jan;8(1):E1-E3

Department of Radiation Oncology, New York Proton Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.02.03DOI Listing
January 2019

Palliative nursing in the 21st century.

Ann Palliat Med 2019 Feb 25;8(Suppl 1):S3-S4. Epub 2019 Jan 25.

Society for the Promotion of Hospice Care, Hong Kong, China; Hong Kong Palliative Nursing Association, Hong Kong, China; Hong Kong College of Medical Nursing, Hong Kong, China; Care for Advanced Diseases Consortium, The Medical Societies of Hong Kong, Hong Kong, China; Hong Kong College of Education and Research Nursing, Hong Kong, China; International Medical and Dental Hypnotherapy Association, Laceyville, USA; The International Federation of Aromatherapist, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.02DOI Listing
February 2019
6 Reads

Dying well with diabetes.

Authors:
June James

Ann Palliat Med 2019 Jan 17. Epub 2019 Jan 17.

Leicester Diabetes Centre, Leicester General Hospital, Leicester, LE5 4PW, UK.

Death is an inevitable part of living. There are undoubtedly clinical and psychological challenges when any individual is passing from life to death. For a person with a long-term condition such as diabetes, these challenges can be compounded and impact on the care and experience of both the individual and their families and carers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.10DOI Listing
January 2019
1 Read

STAT RT: a prospective pilot clinical trial of Scan-Plan-QA-Treat stereotactic body radiation therapy for painful osseous metastases.

Ann Palliat Med 2018 Dec 26. Epub 2018 Dec 26.

Department of Radiation Oncology, University of Virginia, Charlottesville, VA, USA.

Background: Planning and treatment of bone metastases with palliative radiotherapy often requires 1-3 weeks, resulting in patient inconvenience and delayed palliation. We developed an expedited workflow that delivers palliative stereotactic body radiation therapy (SBRT) to painful bone metastases in which CT, planning, quality assurance (QA), and initial treatment are performed one day. This prospective pilot clinical trial evaluates the feasibility, safety, efficacy, and patient satisfaction of this workflow. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/23104
Publisher Site
http://dx.doi.org/10.21037/apm.2018.12.07DOI Listing
December 2018
3 Reads

Invisible and intangible illness: a qualitative interview study of patients' experiences and understandings of conservatively managed end-stage kidney disease.

Ann Palliat Med 2019 Jan 3. Epub 2019 Jan 3.

King's College London, Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, London, UK; Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.

Background: Increasing numbers of older adults are living with kidney disease. For those with comorbidities, conservative management of end-stage kidney disease is a viable option: dialysis may afford limited or no survival benefit, and perceived burdens may outweigh benefits. Conservative management focuses on: maintaining remaining kidney function; symptom management; and quality of life. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.06DOI Listing
January 2019
3 Reads

Palliation of bone metastases-exploring options beyond radiotherapy.

Ann Palliat Med 2019 Jan 2. Epub 2019 Jan 2.

Division of Radiation Oncology, Sunnybrook Hospital, Toronto, Ontario, Canada.

Multiple new options are available in the palliation of bone metastases. Most of these techniques can be used in conjunction with radiation therapy either before or after and are now giving patients who have reached dose limitations new options. These techniques can also be used with vertebroplasty (VP) to increase structural stability post tumor ablation. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/23203
Publisher Site
http://dx.doi.org/10.21037/apm.2018.12.04DOI Listing
January 2019
7 Reads

Clues to improve the cost-effectiveness of radiotherapy for brain metastases from non-small cell lung cancer: cost reduction, patient selection, and better understanding of neurocognitive deterioration.

Ann Palliat Med 2018 Dec 12. Epub 2018 Dec 12.

Department of Radiology and Radiation Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.02DOI Listing
December 2018

Economic burden of brain metastases in patients with non-small cell lung cancer: costs and implications.

Ann Palliat Med 2018 Dec 25. Epub 2018 Dec 25.

Department of Clinical Oncology, Tuen Mun Hospital, Hong Kong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.03DOI Listing
December 2018

The challenge of brain metastases from non-small cell lung cancer is not only an economical issue.

Ann Palliat Med 2018 Dec 12. Epub 2018 Dec 12.

Department Radiation Oncology, Institut Jules Bordet, Université Libre Bruxelles, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.05DOI Listing
December 2018

Annals of Palliative Medicine is now indexed in Science Citation Index Expanded (SCIE).

Authors:
Charles B Simone

Ann Palliat Med 2019 Jan;8(1):102-103

New York Proton Center, New York, NY 10035, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2019.01.03DOI Listing
January 2019
1 Read

What are the criteria for response to cachexia treatment?

Authors:
Jeffrey Crawford

Ann Palliat Med 2019 Jan;8(1):43-49

Duke Cancer Institute, Duke University, Durham, NC, USA.

The treatment of cancer cachexia remains an unmet medical need. One of the barriers to the development and approval of effective interventions has been the lack of agreement on the proper endpoints for study. The international consensus definition of cancer cachexia focuses on 3 major components of the syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.08DOI Listing
January 2019

Cancer cachexia is defined by an ongoing loss of skeletal muscle mass.

Ann Palliat Med 2019 Jan;8(1):3-12

Division of Human Nutrition, University of Alberta, Edmonton, Alberta, Canada.

Since 2007, a quantitative, specific and precise approach to the detection of muscle loss has become accessible with the advent of image-based assessments. Computed tomography images acquired as part of standard cancer care are the serendipitous substrate for these analyses. Three radiologically-determined abnormalities, sarcopenia (severe muscle depletion), catabolic loss of muscle over time, and reduced muscle radiation attenuation associate with progressive functional impairment, treatment-related complications, reduced quality of life, and mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.12.01DOI Listing
January 2019
6 Reads

Perinatal bereavement and palliative care offered throughout the healthcare system.

Ann Palliat Med 2019 Feb 22;8(Suppl 1):S22-S29. Epub 2018 Nov 22.

Kaiser Permanente Santa Rosa, Santa Rosa, CA, USA.

The aims of this article are twofold: (I) provide a general overview of perinatal bereavement services throughout the healthcare system and (II) identify future opportunities to improve bereavement services, including providing resources for the creation of standardized care guidelines, policies and educational opportunities across the healthcare system. Commentary is provided related to maternal child services, the neonatal intensive care unit (NICU), prenatal clinics, operating room (OR) and perioperative services, emergency department (ED), ethics, chaplaincy and palliative care services. An integrated system of care increases quality and safety and contributes to patient satisfaction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.11.03DOI Listing
February 2019
4 Reads

Are we better a decade later in the accuracy of survival prediction by palliative radiation oncologists?

Ann Palliat Med 2018 Nov 21. Epub 2018 Nov 21.

Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.

Background: Clinician predicted survival (CPS) plays a crucial role in palliative care, informing physicians of appropriate treatment best suited to the patient. The primary objective of this study was to assess the accuracy of CPS of cancer patients referred for palliative radiotherapy. Secondary objectives included an analysis of factors predictive of accurate CPS, comparisons of the accuracy of survival predictions over subsequent clinic visits, and comparisons to the previous study in the Rapid Response Radiotherapy Program (RRRP) in 2005. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.11.02DOI Listing
November 2018
1 Read

Prokinetics and ghrelin for the management of cancer cachexia syndrome.

Ann Palliat Med 2019 Jan 5;8(1):80-85. Epub 2018 Nov 5.

Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Cancer cachexia (CC) is one of the most distressing syndromes for both patients and their families. CC can have an impact on patient reported quality of life and overall survival. It is often associated with symptoms such as fatigue, depressed mood, early satiety, and anorexia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.11.01DOI Listing
January 2019

External beam radiation therapy (EBRT) for asymptomatic bone metastases in patients with solid tumors reduces the risk of skeletal-related events (SREs).

Ann Palliat Med 2018 Nov 6. Epub 2018 Nov 6.

Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.

Background: The potential benefit of administering external beam radiation therapy (EBRT) to patients with asymptomatic bone metastases has rarely been addressed in clinical investigations. The aim of this study was to determine if cancer patients who were treated with EBRT for asymptomatic bone metastases experienced later onset of pain and skeletal-related events (SREs) than those who were untreated.

Methods: A retrospective chart review was conducted for prostate, breast, and lung cancer patients with asymptomatic bone metastases treated at a single cancer center from 2007 to 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.10.04DOI Listing
November 2018

A longitudinal cohort study of symptoms and other concerns among Nigerian people with stages 3-5 chronic kidney diseases: study protocol.

Ann Palliat Med 2018 Oct 17. Epub 2018 Oct 17.

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, Cicely Saunders Institute, Department of Palliative Care, Policy & Rehabilitation, London, UK.

Background: The burden of symptoms and other concerns in chronic kidney disease (CKD) is known to be high, adversely affecting the quality of life of the growing number of those with this condition in developing countries. In this paper, we describe the protocol of a longitudinal observational study among people living with CKD. The study is developed to assess the bio-psychosocial factors associated with palliative care symptoms and concerns, and pattern of health services usage among Nigerians with stages 3-5 CKD. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/21860
Publisher Site
http://dx.doi.org/10.21037/apm.2018.10.03DOI Listing
October 2018
12 Reads

Defining the radiation oncologist's role in palliative care and radiotherapy.

Ann Palliat Med 2018 Nov 6. Epub 2018 Nov 6.

Department of Radiation Oncology, University of Washington, Washington, DC, USA.

Radiation oncologists play an important role in the palliative care of advanced cancer patients. The article discusses the various clinical indications of palliative radiation therapy, which include the control of bone pain, acute treatment of cord compression, the control of thoracic and gastrointestinal symptoms. The importance of survival estimates for individualization of radiation therapy regime is elaborated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.10.02DOI Listing
November 2018

Lipid metabolism in cancer cachexia.

Authors:
Shalini Dalal

Ann Palliat Med 2019 Jan 30;8(1):13-23. Epub 2018 Oct 30.

Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

Cancer cachexia, characterized by losses in muscle and adipose tissue (AT), is associated with poor quality of life and prognosis, and lacks effective therapies. Both tumor- and host- derived factors disrupt normal metabolism and are vital to the catabolic drive in cancer cachexia. While muscle loss has long dominated cachexia research, recent work conducted predominantly in rodent models has begun to recognize the significance of AT lipid metabolism alterations in the development and progression of cancer cachexia. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/22092
Publisher Site
http://dx.doi.org/10.21037/apm.2018.10.01DOI Listing
January 2019
4 Reads

Assuaging listener distress from patient death rattle.

Ann Palliat Med 2019 Feb 27;8(Suppl 1):S58-S60. Epub 2018 Sep 27.

Wayne State University, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.09.03DOI Listing
February 2019
2 Reads

Measuring cachexia-diagnostic criteria.

Authors:
Rony Dev

Ann Palliat Med 2019 Jan 7;8(1):24-32. Epub 2018 Sep 7.

Department of Symptom Control & Palliative Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Cancer cachexia is characterized by the loss of lean body mass with or without the loss of fat and is associated with increased susceptibility to treatment related toxicities, decreased quality of life, functional impairment, and increased cancer-related mortality. Uncontrolled symptoms which impair nutritional intake, metabolic derangements including elevated energy expenditure and increased catabolism, and chronic inflammation contribute to the development of cancer cachexia. Weight loss in cancer patients is not readily reversible by conventional nutritional support. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.07DOI Listing
January 2019

Re-analysis of symptom clusters in advanced cancer patients attending a palliative outpatient radiotherapy clinic.

Ann Palliat Med 2018 Sep 5. Epub 2018 Sep 5.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

Background: Cancer patients often present with several concurrent symptoms. There is evidence to suggest that related symptoms can cluster together in stable groups. The present study sought to identify symptom clusters in advanced cancer patients using the Edmonton Symptom Assessment System (ESAS) in a palliative outpatient radiotherapy clinic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.06DOI Listing
September 2018
1 Read

Health-related quality of life across cancer cachexia stages.

Ann Palliat Med 2019 Jan 5;8(1):33-42. Epub 2018 Sep 5.

McGill Nutrition and Performance Laboratory, Supportive and Palliative Care Division, McGill University Health Centre, Montreal, Quebec, Canada.

Cancer cachexia (CC) is common in advanced cancer and is accompanied by negative effects on health-related quality of life (HRQOL). However, methods to identify the impact of CC on HRQOL are limited. Single questionnaire items may provide insight on the effect of CC on HRQOL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.04DOI Listing
January 2019

Sarcopenia associated with chemotherapy and targeted agents for cancer therapy.

Ann Palliat Med 2019 Jan 7;8(1):86-101. Epub 2018 Sep 7.

Cancer Center, Geisinger Medical Center, Danville, PA, USA.

Clinicians often believe that cachexia is caused by cancer and anorexia as a toxicity of chemotherapy or targeted anti-cancer agents. It is now recognized that chemotherapy and certain targeted agents cause sarcopenia which reduce physical function and quality of life. Pre-treatment sarcopenia predicts chemotherapy toxicity, reduced response, increased disability, poor anti-tumor response and survival. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.02DOI Listing
January 2019
3 Reads

The use of Do-Not-Resuscitate-Order equivalents in pediatric palliative care medicine in Germany.

Ann Palliat Med 2018 Sep 4. Epub 2018 Sep 4.

Division of Pediatric Hematology and Oncology, Department of Child and Adolescent Health, University Medical Center Göttingen, Göttingen, Germany.

Background: In the last years, the structure of Pediatric Palliative Care in Germany has developed more and more. Since 2007, there is a legal claim for a specialized palliative care in German which also applies to children. Therefore, the need of an advance care planning for children is frequently discussed. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/21101
Publisher Site
http://dx.doi.org/10.21037/apm.2018.07.08DOI Listing
September 2018
10 Reads

Perspectives of patients, family caregivers and health professionals on the use of outcome measures in palliative care and lessons for implementation: a multi-method qualitative study.

Ann Palliat Med 2018 Oct;7(Suppl 3):S137-S150

Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, UK; Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.

Background: Routine use of outcome measures in palliative care is recommended to demonstrate and improve quality of care. The use of outcome measures is relatively recent in UK specialist palliative care services and understanding their use in practice is key to successful implementation. We therefore aimed to explore how patient-centred outcome measures are used in specialist palliative care, and identify key considerations for implementation. Read More

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/21366/21255
Publisher Site
http://dx.doi.org/10.21037/apm.2018.09.02DOI Listing
October 2018
12 Reads

Challenging but beneficial: using outcome measurement in routine care for patients with advanced disease.

Ann Palliat Med 2018 Oct;7(Suppl 3):S135-S136

Director of the Department of Palliative Medicine, Chair for Palliative Medicine, Munich University Hospital, München, Germany; Claudia.

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/21179/21254
Publisher Site
http://dx.doi.org/10.21037/apm.2018.09.01DOI Listing
October 2018
7 Reads

Radiation therapy and delayed emesis.

Authors:
Richard J Gralla

Ann Palliat Med 2018 10 23;7(4):479-480. Epub 2018 Aug 23.

Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.03DOI Listing
October 2018
2 Reads

Combination therapy in cachexia.

Ann Palliat Med 2019 Jan 27;8(1):59-66. Epub 2018 Aug 27.

Virginia Commonwealth University, Richmond, VA, USA.

Since Cancer cachexia is defined as a "multifactorial syndrome", an effective therapeutic approach might be comprehensive multi-faceted treatment that targets different pathophysiological mechanisms simultaneously. The defining features of cancer cachexia, such as weight loss, reduced food intake, and chronic inflammation, might provide both a framework for classification of cachexia and a rationale for identifying multiple therapeutic targets. Past efforts to treat cachexia with nutritional or medical interventions may have disappointed because they were directed at a single domain of the syndrome, such as anorexia or muscle wasting, usually with a single therapeutic agent. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.08.05DOI Listing
January 2019

A review of cachexia: a tribute to Ken Fearon.

Ann Palliat Med 2019 01 7;8(1):1-2. Epub 2018 Aug 7.

FT McGraw Chair in the Treatment of Cancer, Chair, Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/20667
Publisher Site
http://dx.doi.org/10.21037/apm.2018.08.01DOI Listing
January 2019
16 Reads

Immunotherapy and radiotherapy for metastatic cancers.

Ann Palliat Med 2018 Aug 22. Epub 2018 Aug 22.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA.

Immune checkpoint inhibitors have emerged as a breakthrough therapy in the treatment in various metastatic cancers. In parallel, the role of radiotherapy in metastatic cancers has been expanding to include stereotactic ablative radiotherapy for oligometastases, in addition to the more conventional palliation of symptoms. Thus, many patients are appropriate candidates for both radiation and immunotherapy-highlighting the need for data to guide this treatment combination in patients with metastatic disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm.2018.07.10DOI Listing

Perinatal palliative care: is palliative care really available to everyone?

Ann Palliat Med 2018 10 2;7(4):487-488. Epub 2018 Aug 2.

Woman's and Child's Department, Pediatric Pain and Palliative Care Service, University of Padua, Padua, Italy.

View Article

Download full-text PDF

Source
http://apm.amegroups.com/article/view/20613
Publisher Site
http://dx.doi.org/10.21037/apm.2018.07.09DOI Listing
October 2018
13 Reads