414 results match your criteria Annals of neurosciences[Journal]


Yoga: Can it be integrated with treatment of neuropathic pain?

Ann Neurosci 2019 Apr 1;26(2):82-91. Epub 2019 Apr 1.

Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Neuropathic pain (NP) is a debilitating condition that may result from spinal cord injury (SCI). Nearly 75% of all SCI results in NP affecting 17,000 new individuals in the United States every year, and an estimated 7-10% of people worldwide. It is caused by damaged or dysfunctional nerve fibers sending aberrant signals to pain centers in the central nervous system causing severe pain that affects daily life and routine. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894618PMC

Creating a role model for "Academicians" Social Responsibility (ASR) synergizing with Swachh Bharat Abhiyaan: A campus hygiene initiative by PGIMER, Chandigarh.

Ann Neurosci 2019 Apr 1;26(2):75-81. Epub 2019 Apr 1.

Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: The state of disarray from unhygienic conditions and excessive litter throughout urban highways, alleyways, and byways across rural and urban localities of India is abysmal. Such unsanitary conditions impinge upon the future health and welfare of its citizens, tourists and economic development.

Purpose: The NRL volunteered PGIMER's campus hygiene initiative" is a pioneering effort spearheaded in compliance with Indian Prime Minister's call that citizens of India work together to establish a cleaner and healthier environment. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894620PMC

Impact of yoga based lifestyle intervention on psychological stress and quality of life in the parents of children with retinoblastoma.

Ann Neurosci 2019 Apr 1;26(2):66-74. Epub 2019 Apr 1.

Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Background: Childhood cancers are associated with a psychological burden to the parents and hence, decline their mental and physical health and overall quality of life.

Purpose: The purpose of the present study is to investigate the impact of 12-weeks yoga based lifestyle intervention on psychological stress and quality of life in the parents of children affected with retinoblastoma.

Method: Single arm prospective clinical trial conducted from October 2015 to October 2017 at the Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894619PMC

Folic Acid Modulates Matrix Metalloproteinase-9 Expression Following Spinal Cord Injury.

Ann Neurosci 2019 Apr 1;26(2):60-65. Epub 2019 Apr 1.

Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792.

Background: Treatment of spinal cord injury (SCI) induced neuropathic pain (NP) proves to be extremely clinically challenging as the mechanism behind SCINP is poorly understood. Matrix metalloproteinase (MMP) is largely responsible for the early disruption of the blood spinal cord barrier. This system initiates macrophage infiltration and degradation of myelin, which plays a pivotal role in how NP occurs. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894625PMC

Organic solvents can influence acetylcholine neurotransmission in .

Ann Neurosci 2019 Apr 1;26(2):57-59. Epub 2019 Apr 1.

Center for Preclinical and Translational Medicine Research.

Background: Identification of novel drugs by bio-prospecting natural products like various parts of the plants, or other extracts and drug discovery requires differential fractionation with various organic solvents followed by their concentration through evaporation under nitrogen gas, which is a standard practice.

Purpose: Determination of contribution of vehicle control of organic solvents (chloroform, ethanol, ethyl acetate and n-hexane) processed in the similar manner in the modulation of acetylcholine(ACh) neurotransmission in , Aldicarb induced paralysis assay.

Methods: The organic solvents concentrated as described in background was used to identify their contribution in ACh modulation through ACh esterase inhibitor, Aldicarb, treatment of , which leads to time dependent paralysis of the worms. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894621PMC

Role of MEK-ERK signaling mediated adhesion of glioma cells to extra-cellular matrix: Possible implication on migration and proliferation.

Ann Neurosci 2019 Apr 1;26(2):52-56. Epub 2019 Apr 1.

Department of Neurochemistry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru 560029, India.

Background: Glioblastoma represents the most common primary brain tumor with a worst prognosis despite developments in neurosurgery and chemoradiotherapy. Detachment of the cells from the primary tumor tissue is a prerequisite for their dispersion and spreading. Initial and incessant dispersal of tumor cells from the primary tumor tissue renders GBM refractory to comprehensive surgical removal and increases the chance of recurrence and poorer prognosis. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894623PMC

Yoga: Impact on sperm genome and epigenome - clinical consequences.

Ann Neurosci 2019 Apr 1;26(2):49-51. Epub 2019 Apr 1.

Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

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http://dx.doi.org/10.5214/ans.0972.7531.260202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894624PMC

Narendra Modi's citizen centered Yoga-Diabetes Management Program: Will Indian State install Integrative Medicine in premier Institutes?

Authors:
Akshay Anand

Ann Neurosci 2019 Apr 1;26(2):47-48. Epub 2019 Apr 1.

Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh (India).

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http://dx.doi.org/10.5214/ans.0972.7531.260201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894622PMC

Development and implementation of ZED-YOG quality module: development initiatives.

Ann Neurosci 2019 Jan 1;26(1):37-44. Epub 2019 Jan 1.

Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Background: Government initiatives and schemes for global healthcare improvement require efficient implementation which can transform the quality standards. We redefined the purview of Good Laboratory Practices (GLP) in the basic research investigations in order to create a benchmark of quality standards for conducting translational research.

Methods: We propose (ZED-YOG) as a management tool for funding agencies to monitor data generated in labs funded by them. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894630PMC
January 2019

Negative geotaxis: An early age behavioral hallmark to VPA rat model of autism.

Ann Neurosci 2019 Jan 1;26(1):25-31. Epub 2019 Jan 1.

Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, INDIA.

Background: Negative geotaxis (NG) is an important parameter, commonly used in study of different CNS diseases and neurodevelopmental disorders. Neurobehavioural change following brain injury was easily identified by negative geotaxis.

Purpose: Although NG is evaluated in the settings of ASD, most of the studies are conducted for short duration (1-3 day) and the overall trend of acquisition of NG is not evaluated. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894633PMC
January 2019

Guinness world record attempt as a method to pivot the role of Yoga in Diabetes management.

Ann Neurosci 2019 Jan 1;26(1):21-24. Epub 2019 Jan 1.

Directorate of Sports, Panjab University, Chandigarh, India.

Background: Attempts for Guinness world record have continued worldwide but these attempts were rarely aimed to promote public health. Diabetes is one of the rapidly growing lifestyle disorders in India which requires awareness reinforcements among the local population. In recent studies, Yoga has proved to be useful in lifestyle modification and Diabetes management. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894626PMC
January 2019

Anti-brain cancer activity of chloroform and hexane extracts of Miers: an perspective.

Ann Neurosci 2019 Jan 1;26(1):10-20. Epub 2019 Jan 1.

Department of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab 143005, India.

Background: Plants have been suggested as safest source of therapeutic agents, with multi targeted mode of action and least side effects. commonly known as Guduchi in India, is one of the most highly valued herbs in Ayurvedic medicine. It possesses potential anti-cancer, anti-inflammatory, hepatoprotective, anti-diabetic, immune-stimulatory and various other beneficial activities. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894632PMC
January 2019

Gender differences in brain processes during inhibition of manual movements programs.

Ann Neurosci 2019 Jan 1;26(1):4-9. Epub 2019 Jan 1.

Lesya Ukrainka Eastern European National University, Lutsk, Ukraine.

Background: Motor response suppression can be regarded as an important aspect of the executive control, as a way of changing the behavioral pattern depending on the internal state or external factors.

Purpose: The aim of our study was to examine whether there were differences in the ability of cortical inhibition of triggered motor program (in the context of the Stop-Signal task) between females and males.

Methods: We examined differences in the patterns of event-related EEG synchronization/desynchronization (ERS/ERD) in young volunteers under the conditions of complete inhibition of the triggered motor program of a manual movement. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894627PMC
January 2019

Indian PM's evidence based wellness approach inspires politico-scientific activism.

Ann Neurosci 2019 Jan 1;26(1). Epub 2019 Jan 1.

Neuroscience Research Lab, Post Graduate Institute of Medical Education and Research, Chandigarh.

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http://dx.doi.org/10.5214/ans.0972.7531.260102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894634PMC
January 2019

Contemporary Western Medicine has its pitfalls.

Authors:
Denis English

Ann Neurosci 2019 Jan 1;26(1):1-2. Epub 2019 Jan 1.

Florida Foundation for Research.

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http://dx.doi.org/10.5214/ans.0972.7531.260101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894631PMC
January 2019

The International conference on Neuroscience and 36 Annual Meeting of Indian Academy of Neurosciences, 2018.

Ann Neurosci 2019 Jan 1;26(1):45-46. Epub 2019 Jan 1.

Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh-160012, India.

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http://dx.doi.org/10.5214/ans.0972.7531.260109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894629PMC
January 2019

Effect of anapanasati meditation on anxiety: a randomized control trial.

Ann Neurosci 2019 Jan 1;26(1):32-36. Epub 2019 Jan 1.

S-VYASA Yoga University, Bengaluru, Karnataka, India.

Background: Meditation has shown positive results in improving the psychological disorders such as anxiety. There is a need to study the therapeutic benefits of Anapanasati meditation, a mindfulness meditation technique.

Purpose: The study aims at investigating the effect of Anapanasati meditation on individuals with moderate anxiety. Read More

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http://dx.doi.org/10.5214/ans.0972.7531.260107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894628PMC
January 2019

Erratum.

Authors:

Ann Neurosci 2018 12 13;25(4):278. Epub 2018 Dec 13.

[This corrects the article DOI: 10.1159/000487066.]. Read More

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http://dx.doi.org/10.1159/000495264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470402PMC
December 2018
1 Read

Physical Exhaustion Induced Variations in Event-Related Potentials and Cognitive Task Performance in Young Adults.

Ann Neurosci 2018 Dec 14;25(4):299-304. Epub 2019 Jan 14.

Department of Pharmacology, K.M.C. Manipal, Manipal University, Manipal, India.

Background/aims: Physical exhaustion is not always peripheral, and it is the brain that causes the sensation of fatigue either due to decrease of metabolic resources or due to central activation process that regulates attention and performance. This study was undertaken to observe the variations in event-related potentials (ERPs) and cognitive performance after an exhausting physical exercise.

Methods: A total of 60 healthy young adult subjects were included in the study. Read More

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https://www.karger.com/Article/FullText/487845
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http://dx.doi.org/10.1159/000487845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470344PMC
December 2018
21 Reads

Long-Term Surface Electrode Impedance Recordings Associated with Gliosis for a Closed-Loop Neurostimulation Device.

Ann Neurosci 2018 Dec 14;25(4):289-298. Epub 2019 Jan 14.

Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Background: Closed-loop neurostimulation is a novel alternative therapy for medically intractable focal epilepsy for patients who are not candidates for surgical resection of a seizure focus. Electrodes for this system can be implanted either within the brain parenchyma or in the subdural space. The electrodes then serve the dual role of detecting seizures and delivering an electrical signal aimed at aborting seizure activity. Read More

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http://dx.doi.org/10.1159/000481805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470334PMC
December 2018
15 Reads

Volumetric and Morphometric Analysis of Pineal and Pituitary Glands of an Indian Inedial Subject.

Ann Neurosci 2018 Dec 14;25(4):279-288. Epub 2019 Jan 14.

Biomedical Engineering Group, Department of Applied Mechanics, IIT Madras, Chennai, India.

Background: Inedia (Latin for "fasting") is the ability of a person to live without consuming food and water and to sustain solely by prana, the vital life force in Hinduism. According to Ayurveda, sunlight is one of the main sources of prana, and some practitioners believe that it is possible for a person to survive on sunlight alone.

Purpose: In this study, we report the unusual sizes and volumes of both the pineal and pituitary glands in a subject with inedia state for nearly 70 years. Read More

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http://dx.doi.org/10.1159/000487067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470330PMC
December 2018
1 Read

Involvement of Neuropeptide Y in Post-Incisional Nociception in Rats.

Ann Neurosci 2018 Dec 4;25(4):268-276. Epub 2018 Dec 4.

Departments of Anatomy, All India Institute of Medical Sciences, New Delhi, India.

Background: Neuropeptide Y (NPY) is abundantly distributed in the mammalian nervous system. Its role in nociception arising from inflammatory and neuropathic pain conditions has been elucidated. However, its involvement in post-incisional nociception, particularly at the spinal cord level, is relatively unknown. Read More

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https://www.karger.com/Article/FullText/495130
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http://dx.doi.org/10.1159/000495130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470383PMC
December 2018
16 Reads

Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches.

Ann Neurosci 2018 Dec 4;25(4):261-267. Epub 2018 Dec 4.

Department of Neurology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

Background: Amyotrophic lateral sclerosis (ALS), Alzheimer's, and Parkinson's diseases are age-related neurodegenerative diseases. ALS is not a single entity but a syndrome with many different causes. In all 3 diseases, gene mutations account for only 10-15% of cases. Read More

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https://www.karger.com/Article/FullText/495321
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http://dx.doi.org/10.1159/000495321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470336PMC
December 2018
16 Reads

Changes in MIDAS, Perceived Stress, Frontalis Muscle Activity and Non-Steroidal Anti-Inflammatory Drugs Usage in Patients with Migraine Headache without Aura following Ayurveda and Yoga Compared to Controls: An Open Labeled Non-Randomized Study.

Ann Neurosci 2018 Dec 11;25(4):250-260. Epub 2018 Sep 11.

Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (S-VYASA) A Deemed to be University, Bengaluru, India.

Background: There has been a significant increase in the use of complementary and integrative medicine to provide long-term healing solutions in migraine headache patients. Knowing the limitations of conventional medical approach, the present study evaluated the influence of two Indian traditional systems of medicine on migraine-related disability, autonomic variables, perceived stress, and muscle activity in patients with migraine headache without aura.

Methods: Thirty subjects recruited to the Ayurveda and Yoga (AY) group underwent traditional (Bio-purification) using therapeutic Purgation followed by yoga therapy, while 30 subjects of control (CT) group continued on symptomatic treatment (non-steroidal anti-inflammatory drugs [NSAID's]) for 90 days. Read More

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http://dx.doi.org/10.1159/000492269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470355PMC
December 2018
14 Reads

IAN 2017 conference in Odisha.

Ann Neurosci 2018 Dec 11;25(4):247-249. Epub 2018 Sep 11.

Department of Neurology, Neuroscience Research Lab, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1159/000492456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470338PMC
December 2018
3 Reads

Deficit in Memory Is Associated with Paradoxical Regulation of Magnesium and Manganese in Isolated Male Rats.

Ann Neurosci 2018 Dec 23;25(4):241-246. Epub 2018 Aug 23.

Department of Physiology, Tehran University of Medical Science, Tehran, Iran.

Background: Magnesium (Mg) and manganese (Mn) play an important role in brain development and glutathione, the master antioxidant in the brain, is necessary for the cognitive function. This study is aimed at determining the effect of magnesium and manganese concentrations in hippocampus and prefrontal cortex on the glutathione function. The reduction in glutathione leads to memory impairment in -Y-maze in the isolation period. Read More

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https://www.karger.com/Article/FullText/491918
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http://dx.doi.org/10.1159/000491918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470382PMC
December 2018
6 Reads

Categories of Wistar Rats Based on Anxiety Traits: A Study Using Factor and Cluster Method.

Ann Neurosci 2018 Dec 15;25(4):234-240. Epub 2018 Aug 15.

Division of Sleep Research, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

Background: Outcomes of neurobehavioral studies are invariably affected by the variations in the anxiety traits of animals in the same species. Identifying those traits and categorizing them accordingly would improve the reproducibility of results, and reduce the variation in the results from different laboratories.

Purpose: The present study was done to identify the possible groups among the normal population of outbred adult male Wistar rats. Read More

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https://www.karger.com/Article/FullText/492268
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http://dx.doi.org/10.1159/000492268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470331PMC
December 2018
6 Reads

A Sequential Study of Age-Related Lipofuscin Accumulation in Hippocampus and Striate Cortex of Rats.

Ann Neurosci 2018 Dec 15;25(4):223-233. Epub 2018 Aug 15.

School of Studies in Neuroscience, Jiwaji University, Gwalior, India.

Background: The age-pigment, lipofuscin that accumulates in cells intrinsically and progressively with age is considered as the hallmark of aging. This accumulation is more prominent in post-mitotic cells like neurons and also appears in glia.

Purpose: The aim of the present study was to assess the age-associated occurrence and distribution pattern of lipofuscin both in neurons and microglia in various regions of hippocampus and striate cortex. Read More

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http://dx.doi.org/10.1159/000490908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470335PMC
December 2018
1 Read

Is Prevalence of Hypertension Increasing in First-Ever Stroke Patients?: A Hospital-Based Cross-Sectional Study.

Ann Neurosci 2018 Dec 25;25(4):219-222. Epub 2018 Jul 25.

Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Background: Stroke is a devastating and disabling cerebrovascular disease with some amount of residual deficit leading to economic loss. Recent Indian studies have shown a stroke prevalence rate of 471.58/100,000 populations. Read More

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http://dx.doi.org/10.1159/000487066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470354PMC
December 2018
7 Reads

Comparative Morphometry of the Wisconsin Miniature Swine Thoracic Spine for Modeling Human Spine in Translational Spinal Cord Injury Research.

Ann Neurosci 2018 Dec 24;25(4):210-218. Epub 2018 Jul 24.

Department of Animal Sciences, Biomedical and Genomic Research Group, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Background/aims: Spine and spinal cord pathologies and associated neuropathic pain are among the most complex medical disorders to treat. While rodent models are widely used in spine and spinal cord research and have provided valuable insight into pathophysiological mechanisms, these models offer limited translatability. Thus, studies in rodent models have not led to the development of clinically effective therapies. Read More

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http://dx.doi.org/10.1159/000488022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470333PMC
December 2018
12 Reads

Anti-Stress and Glial Differentiation Effects of a Novel Combination of Cucurbitacin B and Withanone (CucWi-N): Experimental Evidence.

Ann Neurosci 2018 Dec 5;25(4):201-209. Epub 2018 Jul 5.

DBT-AIST International laboratory for Advanced Biomedicine (DAILAB), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

Background: Natural extracts and compounds used in traditional home medicine are known for their safety and a variety of health promoting and therapeutic potentials. In contrast to the single molecule mediated targets, the combinational therapies are preferred for their multi-functional and limited toxic regimens and may be useful for disease therapeutics as well as to increase the quality of life during a variety of environmental stresses.

Purpose: We aimed to combine the active ingredients of Chinese () and Indian () ginsengs to develop a natural, efficient, and welfare combinatorial mixture with high anti-stress and glial differentiation potentials. Read More

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https://www.karger.com/Article/FullText/490693
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http://dx.doi.org/10.1159/000490693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470339PMC
December 2018
19 Reads

Role of DNA Methylation in Hypobaric Hypoxia-Induced Neurodegeneration and Spatial Memory Impairment.

Ann Neurosci 2018 Dec 5;25(4):191-200. Epub 2018 Jul 5.

Directorate General Life Sciences, Defence research Development Organisation (DRDO), Government of India, DRDO Bhawan, Rajaji Marg, New Delhi, India.

Hypobaric hypoxia (HH) is a major stress factor that is associated with physiological, biochemical, molecular and genomic alterations. Brain is the organ that reacts sensitively to oxygen deprivation, which leads to oxidative stress and cognitive function impairment. Our previous studies have reported that downregulation of brain derived neurotrophic factor (BDNF) leads to neurodegeneration and memory impairment. Read More

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http://dx.doi.org/10.1159/000490368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470337PMC
December 2018
18 Reads

Study of Ischemia Modified Albumin as a Biomarker in Acute Ischaemic Stroke.

Ann Neurosci 2018 Dec 28;25(4):187-190. Epub 2018 Jun 28.

Narayana Medical College and Hospitals, Nellore, India.

Background And Purpose: Stroke is one of the leading causes of mortality and long-term disability. Prompt diagnosis and treatment of stroke are crucial for a better outcome. A blood test, which serves as a biomarker in rural areas will help in immediately transferring patients to a hospital for thrombolytic therapy. Read More

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http://dx.doi.org/10.1159/000488188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470340PMC
December 2018
8 Reads

Prevalence, Demographic Profile, and Psychological Aspects of Epilepsy in North-Western India: A Community-Based Observational Study.

Ann Neurosci 2018 Dec 12;25(4):177-186. Epub 2018 Jun 12.

Professor Preventive and Social Medicine, SMS Medical College, Jaipur, India.

Aims: This study was undertaken to determine the prevalence of active epilepsy, assess the sociodemographic profile, and psychological aspects of epilepsy in the Jaipur district of Rajasthan, India.

Methods: We conducted a community-based, cross-sectional observational study covering both rural ( = 165,660) and urban ( = 179,142) populations of Jaipur district using a house-to-house survey. An adapted, pre-designed World Health Organization screening questionnaire was used to identify the cases. Read More

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https://www.karger.com/Article/FullText/487072
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http://dx.doi.org/10.1159/000487072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470329PMC
December 2018
33 Reads

Erratum.

Ann Neurosci 2019 01 7;25(3):141-151. Epub 2018 Mar 7.

Department of Pharmaceutics, Faculty of Pharmacy, University of Aleppo, Aleppo, Syrian Arab Republic.

[This corrects the article DOI: 10.1159/000443575.]. Read More

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http://dx.doi.org/10.1159/000487909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400095PMC
January 2019
1 Read

Erratum.

Authors:

Ann Neurosci 2019 01 12;25(3):174. Epub 2018 Jun 12.

[This corrects the article DOI: 10.1159/000464419.]. Read More

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http://dx.doi.org/10.1159/000487177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388546PMC
January 2019
1 Read

Use of Virtual Rehabilitation to Improve the Symmetry of Body Temperature, Balance, and Functionality of Patients with Stroke Sequelae.

Ann Neurosci 2019 Jan 7;25(3):166-173. Epub 2018 Jun 7.

Postgraduate Program in Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, Brazil.

Background: Stroke rehabilitation that is based on the patients' needs, experiences, and priorities requires extensive knowledge and skills to capture and integrate the perspectives of the subject.

Purpose: The objective of this study was to evaluate the acute effect of an occupational therapy protocol associated with virtual reality (VR) on the symmetry of body temperature (BTP), balance, and functionality of patients with stroke sequelae.

Methods: Ten patients (69. Read More

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http://dx.doi.org/10.1159/000488581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388431PMC
January 2019
8 Reads

Altered Micro-RNA Regulation and Neuroprotection Activity of in Alzheimer's Disease Model.

Ann Neurosci 2019 Jan 7;25(3):160-165. Epub 2018 Jun 7.

Department of Anatomy, Neuroscience Research Center, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Background: Amyloid-β peptide (Aβ) is involved in the formation of senile plaques in Alzheimer's disease (AD), and causes neuronal cell death by inducing oxidative stress.

Objective: We investigated the protective effect of extract against the Aβ-induced toxicity in SH-SY5Y cells.

Methods: Methanolic extract from the aerial parts of was prepared by percolation method at room temperature. Read More

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http://dx.doi.org/10.1159/000489551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388430PMC
January 2019
3 Reads

Serum Homocysteine and Behavioral and Psychological Symptoms of Dementia: Is There Any Correlation in Alzheimer's Disease?

Ann Neurosci 2019 Jan 30;25(3):152-159. Epub 2018 May 30.

Department of Radiodiagnosis, King George's Medical University, Lucknow, India.

Background: There are studies showing the relation between serum B12, folate and Behavioral and Psychological symptoms of Dementia (BPSD) in Alzheimer's disease (AD). Serum levels of these vitamins do not reflect actual disease status and therefore checking the serum Homocysteine level is considered a better test. Homocysteine has been found to be associated with cognitive impairment and various psychiatric disorders. Read More

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http://dx.doi.org/10.1159/000487068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388428PMC
January 2019
2 Reads

Motor Recovery after Transplantation of Bone Marrow Mesenchymal Stem Cells in Rat Models of Spinal Cord Injury.

Ann Neurosci 2019 Jan 25;25(3):126-140. Epub 2018 Apr 25.

Department of Physical Medicine and Rehabilitation, Christian Medical College, Vellore, India.

Background: Neuronal tissue has a limited potential to self-renew or get repaired after damage. Cell therapies using stem cells are promising approaches for the treatment of central nervous system (CNS) injuries. However, the clinical use of embryonic stem cells is limited by ethical concerns and other scientific consequences. Read More

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http://dx.doi.org/10.1159/000487069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388433PMC
January 2019
22 Reads

Exercise Improves Recognition Memory and Acetylcholinesterase Activity in the Beta Amyloid-Induced Rat Model of Alzheimer's Disease.

Ann Neurosci 2019 Jan 12;25(3):121-125. Epub 2018 Apr 12.

Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.

Objective: A correlation between physical exercise and cognitive improvement has been found in Alzheimer's disease (AD). This study aimed to investigate the effects of aerobic and resistance exercise on the recognition memory and acetylcholinesterase (AChE) activity in beta amyloid (Aβ) model of AD in rat.

Materials And Methods: Fifty male 8-week-old Wistar rats (250-280 g) were divided into 5 groups ( = 10 each) of control, sham surgery, Aβ-received sedentary, Aβ-received with aerobic exercise and Aβ-received with resistance exercise. Read More

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http://dx.doi.org/10.1159/000488580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388429PMC
January 2019
18 Reads

Retraction Statement.

Authors:

Ann Neurosci 2018 12 13;25(4):277. Epub 2018 Dec 13.

It has been brought to our attention that the paper entitled “Diagnostic efficacy of adenosine deaminase levels in cerebrospinal fluid in patients of tubercular meningitis: A comparison with polymerase chain reaction for Mycobacterium tuberculosis” [Ann of Neurosciences 2010; 17(3): 126–130] written by Chacko F, Modi M, Lal V, Prabhakar S, Rana SV, Arora SK, submitted by the second author has been found to be simultaneously published in another journal with many of the authors being common. (Please also see our ­Expression of Concern published in 2015). The editors have informed the ­Institute of this duplication. Read More

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http://dx.doi.org/10.1159/000495123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302779PMC
December 2018
1 Read

Collective Conversational Peer Review of Journal Submission: A Tool to Integrate Medical Education and Practice.

Ann Neurosci 2018 Jul 3;25(2):112-119. Epub 2018 Apr 3.

Professor of Medicine, Kamineni Institute of Medical Sciences, Nalgonda, India.

Background: In this study, we demonstrate a collective collaborative, conversational, pre-publication peer review of a randomized controlled trial.

Methods: Using Critical Appraisal Skills Programme checklist, a group of research-oriented undergraduate medical and pharmacy students and their teacher collectively on an online forum, discuss and review a randomized controlled trial submitted to the Annals of Neurosciences and the explanatory commentary from each reviewer makes a basic scaffold for critical appraisal of the manuscript.

Results: This method provided the opportunity for students to engage in online interactive training and allowed them to understand tools used for critical appraisal of a study. Read More

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http://dx.doi.org/10.1159/000488135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103343PMC
July 2018
19 Reads

Assessment of Sleep Spindle Density among Genetically Positive Spinocerebellar Ataxias Types 1, 2, and 3 Patients.

Ann Neurosci 2018 Jul 8;25(2):106-111. Epub 2018 Mar 8.

Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India.

Objective: The effect of thalamic degeneration in patients with spinocerebellar ataxias (SCA) and sleep spindle (SS) abnormalities has not been studied so far, although there is a strong association between these disorders. This study was done to evaluate and compare the SS densities (SSDs) of genetically proven autosomal dominant SCA1, SCA2 and SCA3 patients with controls.

Methods: Prospectively and genetically confirmed cases of SCA and controls were recruited. Read More

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https://www.karger.com/Article/FullText/484516
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http://dx.doi.org/10.1159/000484516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103375PMC
July 2018
19 Reads

The Electrical Brain Activity in Men with Different Alpha-Rhythm Characteristics during Manual Movements Executed by the Subdominant Hand.

Ann Neurosci 2018 Jul 14;25(2):98-104. Epub 2018 Feb 14.

Lesia Ukrainka Eastern European National University, Lutsk, Ukraine.

Background: The ability to control motor actions and flexibly interact with the environment is considered one of the main components of the human brain executive functions. The spontaneous electroencephalogram (EEG) is among the physiological techniques making it possible to formulate a direct estimation of specific features of the activity of the human brain during manual movements.

Purpose: This study is devoted to an investigation of brain processes in men with a high or a low individual α-frequency determined during manual movements executed by the subdominant hand. Read More

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https://www.karger.com/Article/FullText/487065
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http://dx.doi.org/10.1159/000487065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103360PMC
July 2018
7 Reads

Alterations in MicroRNA-132/212 Expression Impairs Fear Memory in Goldfish .

Ann Neurosci 2018 Jul 2;25(2):90-97. Epub 2018 Feb 2.

Behavioural Neuroscience Laboratory, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, India.

Background: Earlier, we showed that nicotinamide (NAM) treatment impairs spatial memory through the downregulation of CREB-Sirt 1-brain-derived neurotrophic factor () signaling cascade.

Purpose: In this study, we examine whether NAM treatment alters CREB-regulated genes through -microRNAs.

Method: To test this hypothesis, goldfish () were divided into 2 groups: (i) vehicle group (VEH; double distilled water intra-peritoneally [i. Read More

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http://dx.doi.org/10.1159/000486842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103369PMC
July 2018
57 Reads

Effects of Pelvic Stability Training on Movement Control, Hip Muscles Strength, Walking Speed and Daily Activities after Stroke: A Randomized Controlled Trial.

Ann Neurosci 2018 Jul 25;25(2):80-89. Epub 2018 Jan 25.

Department of Physiotherapy, School of Allied Health Sciences (SOAHS), Bangalore Campus, Manipal University, Bangalore, India.

Background: Pelvic instability is a common occurrence during standing and walking post stroke. Inappropriate muscle activation and poor movement control around the pelvis lead to difficulty in mobility and daily functioning.

Purpose: The purpose of the study was to examine the effects of pelvic stability training on the movement performance of trunk and lower limb, hip muscles strength, walking speed and daily activities after stroke. Read More

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https://www.karger.com/Article/FullText/486273
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http://dx.doi.org/10.1159/000486273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103379PMC
July 2018
7 Reads

Nobel Nominations in Science: Constraints of the Fairer Sex.

Ann Neurosci 2018 Jul 12;25(2):63-78. Epub 2017 Dec 12.

Department of Neurology, Neuroscience Research Laboratory, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Nobel Prize is the highest honor in the scientific community that is bestowed for the contribution of eminent scientists in various spheres of science. Since its inception in 1901, many renowned scientists have received this award. However, when compared to men, women's share as recipients is abysmally low. Read More

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http://dx.doi.org/10.1159/000481906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103368PMC
July 2018
2 Reads

Improvement of 2-Vessel Occlusion Cerebral Ischaemia/Reperfusion-Induced Corticostriatal Electrolyte and Redox Imbalance, Lactic Acidosis and Modified Acetylcholinesterase Activity by Kolaviron Correlates with Reduction in Neurobehavioural Deficits.

Ann Neurosci 2018 Apr 23;25(1):53-62. Epub 2017 Nov 23.

Biochemical Pharmacology and Toxicology Laboratories, Department of Biochemistry, The Federal University of Technology, Akure, Nigeria.

Background: Disruption of electrolyte, redox and neurochemical homeostasis alongside cellular energy crisis is a hallmark of cerebral ischaemia and reperfusion injury.

Purpose: This study investigated the effect of kolaviron (KV) on cortical and striatal cation imbalance, oxidative stress and neurochemical disturbances as well as neurobehavioural deficits in animals subjected to bilateral common carotid artery occlusion (BCCAO)-induced ischaemia/reperfusion injury.

Methods: KV was administered at a dose of 100 or 200 mg/kg to male Wistar rats 1 h before a 30 min BCCAO/4 h reperfusion (I/R). Read More

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http://dx.doi.org/10.1159/000484517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981598PMC
April 2018
45 Reads

B/L Basal Ganglia Lesions in a Child Leading to a Diagnosis of Glucose-6-Phosphate Dehydrogenase Deficiency.

Ann Neurosci 2018 Apr 21;25(1):50-52. Epub 2017 Nov 21.

Department of Radiodiagnosis and Imaging, PGIMER, Chandigarh, India.

Bilateral basal ganglia lesions are a common non-specific finding seen in many diseases. One of the differential diagnoses for it, in a child, is kernicterus occurring due to hyperbilirubinemia. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common cause of severe hyperbilirubinemia. Read More

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https://www.karger.com/Article/FullText/481907
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http://dx.doi.org/10.1159/000481907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981589PMC
April 2018
30 Reads