Diagnostic value of sTREM-1, IL-8, PCT, and CRP in febrile neutropenia after autologous stem cell transplantation.
Ann Hematol 2017 Sep 17. Epub 2017 Sep 17.
Department of Hematology, Medical Oncology, & Pneumology, University Medical Center of the Johannes Gutenberg University, Langenbeckstr.1, 55130, Mainz, Germany.
Infections and infectious complications are the major cause of morbidity and mortality in febrile neutropenic patients after autologous stem cell transplantation. Laboratory biomarkers are helpful for early identification of critically ill patients and optimal therapy management. Several studies in adult non-neutropenic patients proposed sTREM-1 as a superior biomarker for identification of septic patients as well as a predictor for survival in these patients compared with procalcitonin (PCT), C-reactive protein (CRP), or interleukin-8 (IL-8). Read More