981 results match your criteria Annals of gastroenterology[Journal]


Should the economic pillar be included in national, European or global consensuses concerning infection treatments?

Ann Gastroenterol 2020 May-Jun;33(3):326. Epub 2020 Mar 14.

Department of Medicine, Second Medical Clinic, Aristotle University of Thessaloniki, Ippokration Hospital, Thessaloniki, Macedonia (Jannis Kountouras), Greece.

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http://dx.doi.org/10.20524/aog.2020.0462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196624PMC

Authors' reply.

Ann Gastroenterol 2020 May-Jun;33(3):325. Epub 2020 Mar 27.

GI Department Henry Dynant Hospital, Athens, Greece.

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http://dx.doi.org/10.20524/aog.2020.0472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196615PMC

National consensus on infection: the next-day challenge.

Ann Gastroenterol 2020 May-Jun;33(3):324-325. Epub 2020 Mar 27.

Department of Internal Medicine, Second Medical Clinic, Ippokration Hospital, Aristotle University of Thessaloniki, Macedonia, Greece (Apostolis Papaefthymiou, Michael Doulberis, Jannis Kountouras).

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http://dx.doi.org/10.20524/aog.2020.0469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196622PMC

Complementary role of F-FDG and Ga-DOTATATE PET/CT in the surveillance of patients with von Hippel-Lindau syndrome.

Ann Gastroenterol 2020 May-Jun;33(3):323. Epub 2020 Mar 14.

Positron Emission Tomography (PET) Department, Clinical Center (CC), National Institutes of Health (NIH), Bethesda, Maryland, USA (Corina Millo).

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http://dx.doi.org/10.20524/aog.2020.0465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196616PMC

Fish bone perforation of the duodenum.

Ann Gastroenterol 2020 May-Jun;33(3):322. Epub 2020 Feb 12.

Department of Endoscopy (Yuji Amano), New Tokyo Hospital, Chiba, Japan.

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http://dx.doi.org/10.20524/aog.2020.0456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196621PMC
February 2020

Esophagogastroduodenoscopy-induced angina bullosa hemorrhagica of the pharynx.

Ann Gastroenterol 2020 May-Jun;33(3):321. Epub 2020 Mar 27.

Department of Gastroenterology and Hepatology (Kenta Hamada, Yuka Obayashi, Hiroyuki Okada).

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http://dx.doi.org/10.20524/aog.2020.0473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196610PMC

Curative embolization of iatrogenic inferior mesenteric arteriovenous fistula 14 years after right hemicolectomy.

Ann Gastroenterol 2020 May-Jun;33(3):318-320. Epub 2020 Mar 14.

Department of Radiology, Interventional Radiology Unit, AHEPA University Hospital of Thessaloniki (Adam Hatzidakis), Greece.

Inferior mesenteric arteriovenous fistula (IMAVF) is a rare condition with 40 reported cases. It can be of congenital, idiopathic or acquired etiology. Acquired IMAVF occurs after trauma or has an iatrogenic origin due to abdominal interventions, mainly operations involving the left hemi-colon. Read More

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http://dx.doi.org/10.20524/aog.2020.0463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196613PMC

Clinical manifestations, imaging features, and endoscopic management of renal pseudocysts: a case series.

Ann Gastroenterol 2020 May-Jun;33(3):313-317. Epub 2020 Apr 3.

Department of Surgery (Rajesh Gupta), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Renal pseudocysts (RP) are rare and we know little about their presentation and management. In the present case series, we present the pertinent clinico-radiological features as well as the role of endoscopic drainage in symptomatic RP.

Methods: A retrospective analysis was performed of patients with RP seen in our unit over the last 12 years. Read More

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http://dx.doi.org/10.20524/aog.2020.0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196611PMC

Endoscopic ultrasound as a diagnostic and predictive tool in idiopathic acute pancreatitis.

Ann Gastroenterol 2020 May-Jun;33(3):305-312. Epub 2020 Mar 14.

Department of Gastroenterology and Hepatology, "Virgen de las Nieves" University Hospital, Complejo Hospitalario Universitario de Granada, Granada, Spain (Francisco Valverde-López, Eva Julissa Ortega-Suazo, Maria Carmen Fernandez-Cano, Juan Gabriel Martínez-Cara, Eduardo Redondo-Cerezo).

Background: Endoscopic ultrasound (EUS) is useful in the diagnostic workup of idiopathic acute pancreatitis but its role as a predictor of recurrence has not been thoroughly assessed. Our aim was to study the performance of EUS in idiopathic acute pancreatitis, its impact on the natural history of the disease, and the factors related to recurrence.

Methods: Patients with idiopathic acute pancreatitis referred to our endoscopy unit were enrolled and followed, with assessment of the performance of endoscopic retrograde cholangiopancreatography (ERCP), cholecystectomy, and the incidence of recurrence. Read More

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http://dx.doi.org/10.20524/aog.2020.0464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196619PMC

A prospective nationwide study on the impact of the level of sedation on cannulation success and complications of endoscopic retrograde cholangiopancreatography.

Ann Gastroenterol 2020 May-Jun;33(3):299-304. Epub 2020 Apr 13.

Department Surgical and Perioperative Sciences, Umeå University, Sunderby Research Unit, Umeå (Lars Enochsson), Sweden.

Background: Difficult or unsuccessful cannulation of the papilla of Vater is associated with complications during endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study was to investigate whether deep sedation facilitates the cannulation and reduces the complication rate.

Methods: Nationwide data from ERCP procedures were registered prospectively in the web-based Swedish Registry for Gallstone Surgery and ERCP (GallRiks). Read More

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http://dx.doi.org/10.20524/aog.2020.0480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196618PMC

Decreased risk of hepatocellular carcinoma recurrence with direct-acting antivirals compared with no treatment for hepatitis C: a meta-analysis.

Ann Gastroenterol 2020 May-Jun;33(3):293-298. Epub 2020 Mar 27.

Department of Gastroenterology and Hepatology (Felix H. Lui, Alex Duong, Jacqueline Duong, Douglas L. Nguyen).

Background: Studies investigating the association between direct-acting antivirals (DAAs) and the recurrence of hepatocellular carcinoma (HCC) related to hepatitis C (HCV) have yielded conflicting results. The objective of this meta-analysis was to define the short- and long-term recurrence rates of HCC after DAA treatment.

Methods: A search of multiple databases was performed, including Scopus, Cochrane, MEDLINE/PubMed and abstracts from gastroenterology meetings. Read More

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http://dx.doi.org/10.20524/aog.2020.0470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196608PMC

Efficacy and safety of new direct-acting antivirals in kidney transplant recipients with chronic hepatitis C: a single-center study.

Ann Gastroenterol 2020 May-Jun;33(3):285-292. Epub 2020 Apr 14.

Academic Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, Athens, Greece.

Background: The recent interferon-free direct-acting antiviral (DAA) regimens have very good safety and efficacy profiles and are highly recommended for kidney transplant (KT) recipients with chronic hepatitis C (CHC).

Methods: All KT recipients with CHC followed at our hospital and who received therapy with the current DAAs were included. At the baseline visit, demographic, clinical and laboratory variables before and after KT, as well as at the commencement of DAAs, at the end of antiviral therapy and the end of follow up, were recorded, including assessment of glomerular filtration rate (eGFR). Read More

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http://dx.doi.org/10.20524/aog.2020.0481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196623PMC

Use of proton pump inhibitors is associated with a higher risk of pneumonia in cirrhotic patients: a systematic review and meta-analysis.

Ann Gastroenterol 2020 May-Jun;33(3):277-284. Epub 2020 Apr 13.

Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine (Patompong Ungprasert), Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Proton pump inhibitors (PPIs) are commonly prescribed for cirrhotic patients. However, the use of PPIs in these patients may increase the risk of bacterial infection. The current study aimed to investigate the risk of developing pneumonia among cirrhotic patients exposed to PPIs. Read More

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http://dx.doi.org/10.20524/aog.2020.0483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196626PMC

Association of liver cirrhosis severity with anemia: does it matter?

Ann Gastroenterol 2020 May-Jun;33(3):272-276. Epub 2020 Apr 13.

Department of Internal Medicine, Armed Forces Medical College, Pune (Manish Manrai, Parvathi V.S., Basant Pathak).

Background: The etiology of anemia in liver disease is diverse and often multifactorial. Anemia is more severe in advanced stages of liver cirrhosis and can be a predictor of the severity of liver disease.

Methods: In this cross-sectional observational study, we included 181 cirrhotic patients with anemia owing to liver cirrhosis and its complications. Read More

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http://dx.doi.org/10.20524/aog.2020.0478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196620PMC

Short- and long-term outcomes of endoscopic submucosal dissection for non-ampullary duodenal neuroendocrine tumors.

Ann Gastroenterol 2020 May-Jun;33(3):265-271. Epub 2020 Apr 13.

Department of Gastoenterology, Yokohama City University Guraduate School of Medicine (Shin Maeda), Japan.

Background: Endoscopic resection is recommended for non-ampullary duodenal neuroendocrine tumors (NAD-NETs) ≤10 mm in diameter and confined to the submucosal layer, without lymph node or distant metastasis. However, the efficacy and safety of endoscopic submucosal dissection (ESD) for NAD-NET remains unclear. The aim of this study was to assess the short-term efficacy and safety and the long-term outcomes of ESD for NAD-NET. Read More

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http://dx.doi.org/10.20524/aog.2020.0477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196614PMC

Next-generation laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma.

Ann Gastroenterol 2020 May-Jun;33(3):257-264. Epub 2020 Apr 13.

Division of Medicine and Clinical Science, Tottori University Faculty of Medicine, Tottori, Japan.

Background: Photodynamic diagnosis (PDD) is an optical imaging technology based on the fundamental biological features of porphyrin metabolized in cancer cells. We reported the usefulness of laser-based photodynamic endoscopic diagnosis (LPDED) with 5-aminolevulinic acid (5-ALA) for early gastric cancers. However, the first-generation prototype endoscope system had the flaw that the images captured were rather dark. Read More

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http://dx.doi.org/10.20524/aog.2020.0479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196625PMC

The impact of risk factors on gastroparesis at an urban medical center.

Ann Gastroenterol 2020 May-Jun;33(3):250-256. Epub 2020 Apr 2.

Department of Medicine, Division of Gastroenterology and Hepatology, Thomas Jefferson University, Philadelphia, PA (Joseph Yoo, Stephanie Moleski, Anthony J. DiMarino).

Background: Gastroparesis is a complex and poorly understood disease. The literature is lacking with respect to the epidemiology of patient comorbidities and their effect on gastric emptying. We aimed to describe the most common comorbid conditions among patients with gastroparesis in an urban population and quantify the effect of these comorbidities on the severity of delayed gastric emptying (DGE). Read More

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http://dx.doi.org/10.20524/aog.2020.0475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196617PMC

Pulmonary manifestations of chronic liver disease: a comprehensive review.

Ann Gastroenterol 2020 May-Jun;33(3):237-249. Epub 2020 Mar 27.

First Department of Internal Medicine, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens (Evangelos Cholongitas), Greece.

Hepatopulmonary syndrome (HPS) and porto-pulmonary hypertension (PoPH) represent relatively common pulmonary vascular complications of advanced liver disease. Despite distinct differences in their pathogenetic background, both clinical states are characterized by impaired arterial oxygenation and limited functional status, and are associated with increased pre-transplantation mortality. Accumulation of ascitic fluid in the pleural cavity, known as hepatic hydrothorax (HH), is another frequent manifestation of decompensated cirrhosis, which may cause severe respiratory dysfunction, depending on the volume of the effusion, the rapidity of its development and its resistance to therapeutic measures. Read More

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http://dx.doi.org/10.20524/aog.2020.0474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196609PMC

Understanding the microbiome: a primer on the role of the microbiome in colorectal neoplasia.

Ann Gastroenterol 2020 May-Jun;33(3):223-236. Epub 2020 Mar 14.

Department of Surgery, Oregon Health & Science University, Portland, OR (Katherine M. Watson, Vassiliki Liana Tsikitis).

Colorectal cancer is a leading cause of cancer-related death internationally, with mounting evidence pointing to the role of the microbiome in adenoma and cancer development. This article aims to provide clinicians with a foundation for understanding the field of research into the microbiome. We also illustrate the various ways in which the microbiota have been linked to colorectal cancer, with a specific focus on microbiota with identified virulence factors, and also on the ways that byproducts of microbiota metabolism may result in oncogenesis. Read More

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http://dx.doi.org/10.20524/aog.2020.0467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196612PMC

A selective approach for colonoscopy after acute diverticulitis.

Ann Gastroenterol 2020 Mar-Apr;33(2):222. Epub 2020 Feb 14.

Department of Gastroenterology, Amato Lusitano Hospital, Castelo Branco, Portugal.

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http://dx.doi.org/10.20524/aog.2020.0461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049231PMC
February 2020

Hemorrhoid through fistula-in-ano: a rare event case.

Ann Gastroenterol 2020 Mar-Apr;33(2):221. Epub 2020 Feb 12.

Athens Colorectal Laboratory, Athens, Greece (Ioannis D. Gkegkes, Nikolaos Dalavouras, Apostolos P. Stamatiadis).

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http://dx.doi.org/10.20524/aog.2020.0455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049238PMC
February 2020

Endoscopic band ligation for a rectal Dieulafoy's lesion.

Ann Gastroenterol 2020 Mar-Apr;33(2):220. Epub 2020 Feb 12.

Department of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Kyoto, Japan.

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http://dx.doi.org/10.20524/aog.2020.0454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049235PMC
February 2020

Temporal trends of incidence and mortality in Asian-Americans with pancreatic adenocarcinoma: an epidemiological study.

Ann Gastroenterol 2020 Mar-Apr;33(2):210-218. Epub 2020 Feb 12.

Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA (Mohamed M. Gad, Anas M. Saad, Mohannad Abou Saleh, Alfred D. Nelson, Carlos Roberto Simons-Linares).

Background: Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States, with an estimated 45,750 deaths in 2019. Mortality outcomes seem to differ based on the ethnicity of the patients, with most studies focusing on the mortality and survival of Caucasians and African Americans. Little attention has been given, however, to Asian-American patients diagnosed with pancreatic adenocarcinoma (PAC). Read More

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http://dx.doi.org/10.20524/aog.2020.0450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049244PMC
February 2020

Unilateral versus bilateral hilar stents for the treatment of cholangiocarcinoma: a multicenter international study.

Ann Gastroenterol 2020 Mar-Apr;33(2):202-209. Epub 2020 Feb 12.

Department of Gastroenterology, University of Utah, Salt Lake City, UT (Judith Staub, Samuel Thomas, Abdul Hsaeeb, Jennifer Herrick, Tom Greene, Douglas G. Adler).

Background: Endoscopic placement of hilar stents is an accepted palliative therapy for patients with advanced, unresectable cholangiocarcinoma. However, whether unilateral versus bilateral stent placement provides optimal relief continues to be a subject of debate. The aim of this study was to compare the technical and clinical outcomes in patients with inoperable cholangiocarcinoma who received unilateral or bilateral self-expanding metal stents (SEMS). Read More

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http://dx.doi.org/10.20524/aog.2020.0451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049245PMC
February 2020

Direct-acting antiviral treatment for chronic hepatitis C in people who use drugs in a real-world setting.

Ann Gastroenterol 2020 Mar-Apr;33(2):195-201. Epub 2020 Jan 20.

Gastroenterology-Liver Unit, 2 Academic Department of Internal Medicine, Medical School of National and Kapodistrian University of Athens, Hippokration General Hospital, (Kanellos Rafail Koustenis, Olga Anagnostou, Hariklia Kranidioti, Sofia Vasileiadi, Pinelopi Antonakaki, Evangelia Koutli, Paris Pantsas, Melanie Deutsch, Spilios Manolakopoulos).

Background: Direct-acting antivirals (DAAs) offer high cure rates in people who inject drugs (PWID) with hepatitis C virus (HCV) infection. There are concerns regarding lower response rates among PWID in real life. We evaluated the outcome of DAA therapy in PWID in a real-world setting and the factors that affect it. Read More

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http://dx.doi.org/10.20524/aog.2020.0449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049240PMC
January 2020

Simulated performance of flexible sigmoidoscopy-based screening for advanced neoplasia detection in a Greek population.

Ann Gastroenterol 2020 Mar-Apr;33(2):187-194. Epub 2020 Feb 12.

Department of Gastroenterology (Vasilios Papastergiou, Nicoletta Mathou, Athanasios Giannakopoulos, Aikaterini Evgenidi, Eleftherios Schoretsanitis, Konstantina D. Paraskeva).

Background: Flexible sigmoidoscopy (FS) is resource-conserving and may increase adherence to colorectal cancer (CRC) screening compared to total colonoscopy. We investigated the diagnostic performance of FS-based screening for advanced colorectal neoplasia (ACN), including advanced adenomatous neoplasms (AANs), advanced serrated lesions (ASLs) and CRCs.

Methods: Data from 2005 subjects undergoing average-risk screening colonoscopy in a single center in Greece were retrospectively reviewed. Read More

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http://dx.doi.org/10.20524/aog.2020.0458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049233PMC
February 2020

How to increase proximal adenoma detection rate: a meta-analysis comparing water exchange, water immersion and air/CO insufflation methods for colonoscopy.

Ann Gastroenterol 2020 Mar-Apr;33(2):178-186. Epub 2020 Feb 14.

Department of Gastroenterology, University of Utah, Salt Lake City, Utah (Douglas G. Adler), USA.

Background: Recent meta-analyses have demonstrated a higher adenoma detection rate using the water exchange method (WE), compared to water immersion (WI) and air/CO insufflation (ACI). Proximal adenomas have a high miss rate owing to their location and appearance. We performed a systematic review and meta-analysis of studies comparing the WE and WI methods to the ACI method, with a primary focus on proximal adenoma detection rate. Read More

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http://dx.doi.org/10.20524/aog.2020.0459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049237PMC
February 2020

Effectiveness and safety of vedolizumab in inflammatory bowel disease patients aged 60 and over: an observational multicenter UK experience.

Ann Gastroenterol 2020 Mar-Apr;33(2):170-177. Epub 2020 Jan 7.

IBD Centre, Guy's and St. Thomas' NHS Foundation Trust, London (Hajir Ibraheim, Mark A. Samaan, Jonathan Digby-Bell, Peter M. Irving, Irena Norman, Nick Powell).

Background: The GEMINI trials established the efficacy of vedolizumab in moderate-to-severe inflammatory bowel disease (IBD) and demonstrated a favorable safety profile, suggesting it may be advantageous in older patients at greater risk of treatment-related complications. However, there is a paucity of data exploring the outcomes of vedolizumab in this group. Our objective was to determine the clinical effectiveness and safety of vedolizumab in older IBD patients within a real-world multicenter UK cohort. Read More

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http://dx.doi.org/10.20524/aog.2020.0447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049246PMC
January 2020

Retrospective study of idiosyncratic drug-induced liver injury from infliximab in an inflammatory bowel disease cohort: the IDLE study.

Ann Gastroenterol 2020 Mar-Apr;33(2):162-169. Epub 2020 Feb 12.

Department of Gastroenterology, Eastern Health (Thomas Worland, Daniel van Langenberg, Muyur Garg, Amanda Nicoll).

Background: Infliximab therapy may be associated with drug-induced liver injury (DILI), often resembling a drug-induced autoimmune hepatitis. However, the prevalence of DILI in patients receiving infliximab is unclear. Abnormal liver biochemistry is common in patients with inflammatory bowel disease (IBD) and definitive diagnosis may be difficult. Read More

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http://dx.doi.org/10.20524/aog.2020.0453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049241PMC
February 2020

Clinical efficacy and safety of mucosal incision-assisted biopsy for the diagnosis of upper gastrointestinal subepithelial tumors: A systematic review and meta-analysis.

Ann Gastroenterol 2020 Mar-Apr;33(2):155-161. Epub 2020 Feb 14.

Department of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Douglas G. Adler), USA.

Background: Endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNA/FNB) has been traditionally used for making a tissue diagnosis. Several newer techniques are emerging as a viable alternative to EUS-FNA/FNB, including mucosal incision-assisted biopsy (MIAB), with a view to increasing the diagnostic yield for upper gastrointestinal (GI) subepithelial tumors (SETs). We conducted a systematic review and meta-analysis to describe the overall diagnostic yield of MIAB for upper GI SETs. Read More

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http://dx.doi.org/10.20524/aog.2020.0460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049234PMC
February 2020

Efficacy of Hemospray in non-variceal upper gastrointestinal bleeding: a systematic review with meta-analysis.

Ann Gastroenterol 2020 Mar-Apr;33(2):145-154. Epub 2020 Jan 20.

Department of Gastroenterology and Hepatology, University of Kansas Medical Center, Kansas City, Kansas (Amit Rastogi), USA.

Background: Recently, amongst other hemostatic modalities, Hemospray (TC-325) has emerged as an effective method for managing patients with non-variceal upper gastrointestinal bleeding (GIB). We conducted this systematic review and meta-analysis to assess the efficacy of Hemospray in patients with non-variceal upper GIB.

Methods: Our primary outcomes were clinical and technical success; secondary outcomes were aggregate rebleeding, early rebleeding, delayed rebleeding, refractory bleeding, mortality, and treatment failure. Read More

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http://dx.doi.org/10.20524/aog.2020.0448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049242PMC
January 2020

Role of cannabis in inflammatory bowel diseases.

Ann Gastroenterol 2020 Mar-Apr;33(2):134-144. Epub 2020 Feb 12.

Department of Medicine, The Wright Center for Graduate Medical Education (Hemant Goyal), USA.

For many centuries, cannabis (marijuana) has been used for both recreational and medicinal purposes. Currently, there are about 192 million cannabis users worldwide, constituting approximately 3.9% of the global population. Read More

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http://dx.doi.org/10.20524/aog.2020.0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049239PMC
February 2020

Inflammatory bowel disease pathobiology: the role of the interferon signature.

Ann Gastroenterol 2020 Mar-Apr;33(2):125-133. Epub 2020 Feb 12.

Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

The pathogenesis of inflammatory bowel disease (IBD) is still unclear, but includes both inflammatory and autoimmune reactions. Current methodological approaches could better elucidate the cytokine pathways and the genetics involved in the etiopathogenesis of this disease. Interferons (IFNs) are cytokines that play a key role in autoimmune/inflammatory disorders because of their pro- and anti-inflammatory properties as well as their immunoregulatory functions. Read More

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http://dx.doi.org/10.20524/aog.2020.0457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049232PMC
February 2020

Hellenic consensus on infection.

Ann Gastroenterol 2020 Mar-Apr;33(2):105-124. Epub 2020 Jan 7.

Gastroenterology Department, Attikon University Hospital (Konstantinos Triantafyllou), Athens, Greece.

The Hellenic Society of Gastroenterology recently organized the "Hellenic consensus on () infection". The aim of this publication is to report the guidelines in order to aid the national gastroenterology community in the management of infection. Forty-one delegates from all Greek regions, including gastroenterologists, pathologists, clinical microbiologists, epidemiologists and basic scientists, were invited to this meeting. Read More

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http://dx.doi.org/10.20524/aog.2020.0446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049243PMC
January 2020

Why does intestinal metaplasia develop early on gastric mucosa of mucosa-associated lymphoid tissue lymphoma patients?

Ann Gastroenterol 2020 Jan-Feb;33(1):103. Epub 2019 Nov 29.

Pathology Unit, 'San Filippo Neri' Hospital, Rome (Stefano Licci), Italy.

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http://dx.doi.org/10.20524/aog.2019.0440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928485PMC
November 2019

The endosonographic appearance of a type-A choledochocele.

Ann Gastroenterol 2020 Jan-Feb;33(1):102. Epub 2019 Nov 21.

Division of Gastroenterology and Hepatology, Mayo Clinic School of Medicine, 200 First Street SW, Rochester, MN, USA (Mark D. Topazian).

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http://dx.doi.org/10.20524/aog.2019.0433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928484PMC
November 2019

Mucosotomy at the top of the septum facilitates tunneling and clipping during peroral endoscopic myotomy for Zenker's diverticulum (Z-POEM).

Ann Gastroenterol 2020 Jan-Feb;33(1):101. Epub 2019 Oct 8.

Department of Gastroenterology Interventional Endoscopy Program, Massachusetts General Hospital, Boston, MA, USA (Fateh Bazerbachi).

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http://dx.doi.org/10.20524/aog.2019.0424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928482PMC
October 2019

Pancreatic intraductal papillary mucinous neoplasm masquerading as ampullary adenoma: a diagnostic puzzle.

Ann Gastroenterol 2020 Jan-Feb;33(1):98-100. Epub 2019 Nov 29.

2 Department of Surgery, Aretaieion University Hospital, Medical School of Athens, Greece.

Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cystic lesion, remaining mostly asymptomatic. An atypical presentation of such a lesion, initially thought to be an ampullary adenoma, is presented herein. A 78-year-old white male with painless jaundice was treated in a tertiary hospital. Read More

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http://dx.doi.org/10.20524/aog.2019.0435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928474PMC
November 2019

Brain and bone marrow metastases from rectal cancer.

Ann Gastroenterol 2020 Jan-Feb;33(1):95-97. Epub 2019 Oct 8.

Medical Oncology Department, University Hospital of Heraklion, Crete (Konstantina Thomopoulou, Stavroula Manolakou, Andreas Koulouris, Konstantinos Kalbakis, Dimitris Mavroudis, Ioannis Souglakos).

Despite the development of new treatment options based on the molecular characterization of colorectal cancer, 20% of patients present de novo metastatic disease, whereas 30-40% of patients who receive curative treatment relapse during follow up. Herein, we report 2 cases with rectal cancer that developed uncommon sites of metastasis; the first patient had an isolated breast metastasis, while the second patient developed bone marrow infiltration with synchronous brain metastases. In order to evaluate the uncommon metastatic pattern of rectal cancer, we detected and enumerated circulating tumor cells (CTCs) using both immunofluorescence and real-time reverse transcriptase polymerase chain reaction in these patients' peripheral blood. Read More

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http://dx.doi.org/10.20524/aog.2019.0423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928473PMC
October 2019

Validating and expanding the Baveno VI criteria for esophageal varices in patients with advanced liver disease: a multicenter study.

Ann Gastroenterol 2020 Jan-Feb;33(1):87-94. Epub 2019 Oct 23.

First Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis (Theodora Mylopoulou, Kiriaki Vogiatzi, Konstantinos Mimidis).

Introduction: According to the Baveno VI workshop, patients with compensated advanced liver disease, platelet count (PLT) >150,000/μL and liver stiffness measurement (LSM) <20 kPa can avoid screening endoscopy for high-risk varices (HRVs). The purpose of this study was to validate these criteria in a multicenter Greek cohort and consider other approaches that may further decrease the number of endoscopies.

Methods: We prospectively enrolled patients with advanced liver disease (defined as LSM >12 kPa) and evaluated them according to the Baveno VI criteria. Read More

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http://dx.doi.org/10.20524/aog.2019.0429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928480PMC
October 2019

Validation of cutoffs for skeletal muscle mass index based on computed tomography analysis against dual energy X-ray absorptiometry in patients with cirrhosis: the KIRRHOS study.

Ann Gastroenterol 2020 Jan-Feb;33(1):80-86. Epub 2019 Nov 21.

Department of Dietetics Nutrition and School of Health Education Sciences and Harokopio University (Georgiou Alexandra Yannakoulia Mary Meropi D. Kontogianni) Gastroenterology.

Background: Accurate assessments of muscle mass in patients with cirrhosis are necessary in clinical practice. Computed tomography (CT) of the upper abdomen has been proposed as a useful method for quantifying muscle mass. Recently, Carey et al developed specific cutoffs for muscle wasting based on the skeletal muscle index at the L3 vertebra (L3-SMI) for cirrhotic patients. Read More

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http://dx.doi.org/10.20524/aog.2019.0432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928470PMC
November 2019

Heparin bridge is associated with more post-polypectomy bleeding and emergency department visits among anticoagulated patients.

Ann Gastroenterol 2020 Jan-Feb;33(1):73-79. Epub 2019 Nov 1.

Division of Gastroenterology, Brown University, Providence, RI (Mena Bakhit, Steven F. Moss).

Background: Among patients undergoing colonoscopy, anticoagulants are usually stopped and are sometimes substituted by a heparin bridge (hep-bridge). We aimed to assess adverse events associated with hep-bridge compared to temporary cessation of anticoagulants (no-bridge).

Methods: This was a single-center, retrospective cohort study that included anticoagulated patients undergoing colonoscopy between 2013 and 2016 at a Veterans Affairs Medical Center. Read More

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http://dx.doi.org/10.20524/aog.2019.0430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928471PMC
November 2019

Efficacy of colonoscopy after an episode of acute diverticulitis and risk of colorectal cancer.

Ann Gastroenterol 2020 Jan-Feb;33(1):68-72. Epub 2019 Nov 29.

Department of General and Digestive Surgery, (Jeancarlos Jhosmer Trujillo Díaz, Beatriz De Andrés Asenjo, María Ruiz Soriano, Carlos Jezieniecki Fernández, Javier Ortiz de Solórzano Aurusa, Juan Pablo Beltrán de Heredia y Rentería).

Background: Diverticular disease of the colon has a high global prevalence. The guidelines suggest performing a colonoscopy 4-6 weeks after the acute episode to exclude colorectal cancer (CRC). However, these recommendations are based on old studies, when computed tomography was not used to diagnose acute diverticulitis (AD). Read More

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http://dx.doi.org/10.20524/aog.2019.0437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928487PMC
November 2019

Clinical characteristics of colitis induced by taxane-based chemotherapy.

Ann Gastroenterol 2020 Jan-Feb;33(1):59-67. Epub 2019 Nov 21.

Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center (Hamzah Abu-Sbeih, Selvi Thirumurthi, Yinghong Wang).

Background: Limited data are available concerning the clinical features of toxic gastrointestinal (GI) effects of taxane-based therapy. We describe the clinical, endoscopic and histologic features of taxane-induced colitis.

Methods: This retrospective study included cancer patients who received taxane therapy and underwent colonoscopy for GI symptoms from 2000-2018. Read More

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http://dx.doi.org/10.20524/aog.2019.0431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928479PMC
November 2019

Curcumin use in ulcerative colitis: is it ready for prime time? A systematic review and meta-analysis of clinical trials.

Ann Gastroenterol 2020 Jan-Feb;33(1):53-58. Epub 2019 Nov 29.

Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah (Douglas G. Adler), USA.

Background: Curcumin, an active ingredient of the Indian herb turmeric (Curcuma longa), has shown promising anti-inflammatory properties. Studies of its potential benefits in treating patients with ulcerative colitis (UC) are limited. We performed a systematic review and meta-analysis of human randomized placebo controlled trials to evaluate the efficacy of adjunctive therapy with curcumin in treating patients with UC. Read More

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http://dx.doi.org/10.20524/aog.2019.0439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928475PMC
November 2019

Gastrointestinal hypoalgesia in inflammatory bowel disease.

Ann Gastroenterol 2020 Jan-Feb;33(1):45-52. Epub 2019 Nov 29.

Department of Medicine, Division of Gastroenterology and Hepatology (Matthew D. Coates, Shannon Dalessio, August Stuart, Nana Bernasko, Andrew Tinsley, Kofi Clarke, Emmanuelle D. Williams).

Background: Pain perception is critical for detection of noxious bodily insults. Gastrointestinal hypoalgesia in inflammatory bowel disease (IBD) is a poorly understood phenomenon previously linked to poor patient outcomes. We aimed to evaluate the risk factors associated with this condition and to discern characteristics that might differentiate these patients from pain-free quiescent counterparts. Read More

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http://dx.doi.org/10.20524/aog.2019.0442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928483PMC
November 2019

T300A polymorphism is associated with Crohn's disease in a Northwest Greek cohort, but T130M and G290S polymorphisms are not associated with ulcerative colitis.

Ann Gastroenterol 2020 Jan-Feb;33(1):38-44. Epub 2019 Nov 21.

Faculty of Medicine, School of Health Sciences, University of Ioannina (Epameinondas V. Tsianos), Greece.

Background: Crohn's disease (CD) and ulcerative colitis (UC) are well-described disease entities with unknown etiopathogenesis. Environmental, genetic, gut microbiota, and host immune response correlations have been implicated. The role of susceptibility gene polymorphisms, such as ATG16L1 T300A and ECM1 T130M and G290S, is well-described, although controversial findings have been reported. Read More

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http://dx.doi.org/10.20524/aog.2019.0434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928472PMC
November 2019

Diagnostic yield of deep biopsy via endoscopic submucosal dissection for the diagnosis of upper gastrointestinal subepithelial tumors: a systematic review and meta-analysis.

Ann Gastroenterol 2020 Jan-Feb;33(1):30-37. Epub 2019 Nov 29.

Department of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Douglas G. Adler), USA.

Background: Conventionally, endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNA)/EUS-FNB) has been used for tissue diagnosis of upper gastrointestinal (GI) subepithelial tumors (SETs). However, deep biopsy (DB) via endoscopic submucosal dissection (ESD) is emerging as an alternative technique, given the inadequate tissue sampling with EUS-FNA/EUS-FNB. Our aim was to conduct a systematic review and meta-analysis to report the overall diagnostic yield of DB via ESD for upper GI SETs. Read More

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http://dx.doi.org/10.20524/aog.2019.0444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928476PMC
November 2019

High-frequency miniprobe endoscopic ultrasonography in the management of benign esophageal strictures.

Ann Gastroenterol 2020 Jan-Feb;33(1):25-29. Epub 2019 Nov 29.

Department of Surgery (Rajesh Gupta), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Endoscopic ultrasonography (EUS) can predict the response to endoscopic dilatation by delineating the extent of esophageal wall involvement in benign strictures. In contrast to conventional echoendoscopes, the EUS miniprobe can be negotiated across the stricture and thus provide more information. This study retrospectively evaluated the role of miniprobe EUS in predicting the response to endoscopic dilatation in benign esophageal strictures. Read More

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http://dx.doi.org/10.20524/aog.2019.0436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928478PMC
November 2019