2 results match your criteria Annals of clinical pathology[Journal]

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Therapeutic Potential of Arsenic Trioxide (ATO) in Treatment of Hepatocellular Carcinoma: Role of Oxidative Stress in ATO-Induced Apoptosis.

Ann Clin Pathol 2017 4;5(1). Epub 2017 Jan 4.

National Institutes of Health RCMI-Center for Environmental Health, Jackson State University, USA.

Hepatocellular carcinoma (HCC), the dominant form of primary liver cancer, is the sixth most common cancer in the world with more than 700,000 people diagnosed annually. Arsenic trioxide (ATO) has been shown to be a potent anticancer agent in various carcinomas, proving particularly effective in the clinical treatment of relapsed and refractory acute promyelocytic leukemia. However, its bioactivity and molecular mechanisms against HCC has not been fully studied. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713642PMC
January 2017
4 Reads

ESPs Could Indistinctly Activate or Block Multiple Toll-Like Receptors in a Human Monocyte Cell Line.

Ann Clin Pathol 2017 31;5(3). Epub 2017 Mar 31.

Department of Microbiology, University of Puerto Rico-Medical Sciences Campus, USA.

is a parasitic helminth that induces Th2/Treg responses in its mammalian host. Some reports have suggested that ESPs achieve these polarized immune responses by delaying the activation of dendritic cells and macrophages during the early stages of innate immunity, a process that is mediated by TLR4. The present study aimed to investigate whether TLRs other than TLR4 could also be targeted by ESPs. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690573PMC
March 2017
21 Reads
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