944 results match your criteria Annals of cardiothoracic surgery[Journal]


Preface-frozen elephant trunk.

Ann Cardiothorac Surg 2020 May;9(3):E1

Department of Cardiac Surgery, S. Orsola Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.21037/acs-2020-fet-prefaceDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298231PMC

Aortic valve sparing and hybrid arch frozen elephant trunk repair for mega-aortic syndrome.

Ann Cardiothorac Surg 2020 May;9(3):262-264

Division of Cardiac Surgery, Department of Surgery, Western University, London Health Sciences Centre, London, ON, Canada.

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http://dx.doi.org/10.21037/acs.2020.02.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298233PMC

Aortic arch replacement using the branch-first and frozen elephant trunk techniques.

Ann Cardiothorac Surg 2020 May;9(3):259-261

Department of Cardiac Surgery, Austin Health, Melbourne, Australia.

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http://dx.doi.org/10.21037/acs.2020.03.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298237PMC

Frozen elephant trunk: debranch first technique.

Ann Cardiothorac Surg 2020 May;9(3):257-258

Department of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.21037/acs.2020.03.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298245PMC

Total arch repair with frozen elephant trunk for type A acute aortic dissection: the "zone 0 arch repair" strategy.

Ann Cardiothorac Surg 2020 May;9(3):251-253

Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, Japan.

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http://dx.doi.org/10.21037/acs.2020.02.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298236PMC

Mini-access branch-first total arch replacement and frozen elephant trunk procedure-how I do it.

Ann Cardiothorac Surg 2020 May;9(3):246-247

Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.21037/acs-2020-fet-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298228PMC

Mini-access branch-first total arch replacement and frozen elephant trunk procedure.

Ann Cardiothorac Surg 2020 May;9(3):236-243

Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, The University of Sydney, Sydney, NSW, Australia.

Minimally-invasive surgery presents its own unique set of challenges, especially when applied to treatment of aortic arch disease. The key components of mini-access aortic arch surgery include safe circulatory control, adequate organ protection, and meticulous surgical technique. This article describes how to perform branch-first total arch replacement with the frozen elephant trunk (FET) procedure for distal arch aneurysms. Read More

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http://dx.doi.org/10.21037/acs-2020-fet-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298242PMC

Acute type A aortic dissection: the role of frozen elephant trunk.

Authors:
Hitoshi Ogino

Ann Cardiothorac Surg 2020 May;9(3):233-235

Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.21037/acs-2019-fet-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298248PMC

The frozen elephant trunk technique in acute and chronic aortic dissection: intraoperative setting and patient selection are key to success.

Ann Cardiothorac Surg 2020 May;9(3):230-232

Department of Cardiovascular Surgery, University Heart Centre Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.21037/acs-2019-fet-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298241PMC

Frozen elephant trunk: reflections of the UK Aortic Group.

Ann Cardiothorac Surg 2020 May;9(3):228-229

Clinical Lead for Cardiac Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.

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http://dx.doi.org/10.21037/acs.2020.02.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298240PMC

Distal repair after frozen elephant trunk: open or endovascular?

Ann Cardiothorac Surg 2020 May;9(3):226-227

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.21037/acs-2020-fet-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298251PMC

Aortic arch repair with frozen elephant trunk versus conventional elephant trunk.

Ann Cardiothorac Surg 2020 May;9(3):223-225

Department of Cardiovascular Surgery, Texas Heart Institute, Houston, Texas, USA.

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http://dx.doi.org/10.21037/acs.2020.02.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298238PMC

Frozen elephant trunk-the Bologna experience.

Ann Cardiothorac Surg 2020 May;9(3):220-222

Cardiac Surgery Unit, Cardio-Thoracic-Vascular Department, S. Orsola Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.21037/acs.2020.03.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298234PMC

Renal protective effect of the aortic balloon occlusion technique in total arch replacement with frozen elephant trunk.

Ann Cardiothorac Surg 2020 May;9(3):209-219

Department of Cardiovascular Surgery, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

Background: Organ dysfunction caused by hypothermic circulatory arrest continues to concern surgeons. The aortic balloon occlusion (ABO) technique can significantly shorten the circulatory arrest time in total arch replacement with frozen elephant trunk (TAR with FET). This study aims to analyze the renal protective effect of the ABO technique and to analyze the predictors of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) after TAR with FET. Read More

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http://dx.doi.org/10.21037/acs-2019-0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298247PMC

Is the frozen elephant trunk technique justified for chronic type A aortic dissection in Marfan syndrome?

Ann Cardiothorac Surg 2020 May;9(3):197-208

Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.

Background: Chronic type A aortic dissection (cTAAD) in Marfan syndrome (MFS) is rare. Surgical experience is limited and the role of frozen elephant trunk (FET) technique remains undefined. We seek to evaluate the safety and efficacy of the total arch replacement (TAR) and FET technique for cTAAD in MFS. Read More

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http://dx.doi.org/10.21037/acs.2020.03.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298250PMC

Hybrid arch frozen elephant trunk repair: evidence from the Canadian Thoracic Aortic Collaborative.

Ann Cardiothorac Surg 2020 May;9(3):189-196

Division of Cardiac Surgery, Department of Surgery, Western University, London, ON, Canada.

Background: The frozen elephant trunk (FET) technique has become an increasingly popular strategy for aortic reconstruction in the setting of extensive thoracic aortic aneurysms or dissections. The objective of this study is to report on the Canadian experience with the FET technique in both the elective and emergent settings.

Methods: A total of 167 consecutive patients (mean age 65±13 years, 30% female, 25% re-operation) underwent elective (70%) and non-elective (30%) aortic arch reconstruction with the FET technique between May 2008 and October 2019 in six centers of the Canadian Thoracic Aortic Collaborative (CTAC). Read More

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http://dx.doi.org/10.21037/acs-2020-fet-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298239PMC

Results of frozen elephant trunk from the international E-vita Open registry.

Ann Cardiothorac Surg 2020 May;9(3):178-188

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, Essen, Germany.

Background: Over the years, frozen elephant trunk (FET) has become the treatment of choice for multisegmental thoracic aortic disease. This multicenter study presents the evolution of FET results using the E-vita Open hybrid graft with respect to institutional experience and time.

Methods: The data of International E-vita Open registry were studied according to the institutional experience of the participating centers (high- versus low-volume centers) and according to the evolution of FET treatment during time (1 period, 2005-2011 versus 2 period, 2012-2018). Read More

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http://dx.doi.org/10.21037/acs-2020-fet-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298229PMC

Open total arch replacement with trifurcated graft and frozen elephant trunk.

Ann Cardiothorac Surg 2020 May;9(3):170-177

Department of Cardio-Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

Background: The frozen elephant trunk (FET) technique was introduced in Hannover Medical School in 2001 to treat patients with complex aortic arch pathologies. Since 2012, we primarily use the trifurcated Thoraflex Hybrid FET graft. In this article, we report our experience with the trifurcated FET graft. Read More

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http://dx.doi.org/10.21037/acs.2020.03.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298230PMC

Frozen elephant trunk with straight vascular prosthesis.

Ann Cardiothorac Surg 2020 May;9(3):164-169

Vascular & Endovascular Surgery, Royal Blackburn Teaching Hospital, Blackburn, UK.

We present a recapitulation of 15 years of experience starting with conception, inception, development, and clinical implementation and application of the E-vita open hybrid graft. Concomitantly, we delve into surgical techniques that shaped our clinical results. Introduced in February 2005, the novel "Essen I Prosthesis", was first-in-human surgically implanted. Read More

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http://dx.doi.org/10.21037/acs-2020-fet-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298244PMC

Frozen elephant trunk with Frozenix prosthesis.

Authors:
Yutaka Okita

Ann Cardiothorac Surg 2020 May;9(3):152-163

Cardio-Aortic Center, Takatsuki General Hospital, Osaka, Japan.

This paper presents the clinical applications of the Japanese-made frozen elephant trunk (FET, Frozenix). The historical aspects of FET development, manufacture and structure of Frozenix, video images of a representative case, and a summary of a multi-centre Japanese Frozenix study, J-ORCHESTRA, are discussed. Read More

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http://dx.doi.org/10.21037/acs.2020.03.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298232PMC

Long-term outcomes of the frozen elephant trunk procedure: a systematic review.

Ann Cardiothorac Surg 2020 May;9(3):144-151

Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.

Background: The frozen elephant trunk (FET) procedure remains an increasingly popular approach to address complex multi-segmental aortic pathologies, owing to their ability to promote false lumen thrombosis and reduce the need for second-stage operations. While the short-term outcomes of such procedures have been shown to be acceptable, much less is known regarding long-term outcomes. This systematic review evaluates long-term outcomes of the FET procedure. Read More

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http://dx.doi.org/10.21037/acs.2020.03.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298235PMC

Transitioning to total artificial heart for patients supported with short term mechanical circulatory devices.

Ann Cardiothorac Surg 2020 Mar;9(2):141-143

Department of Cardiovascular Surgery, Cardiac Institution, La Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.

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http://dx.doi.org/10.21037/acs.2020.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160632PMC

Insertion of the total artificial heart in the Fontan circulation.

Ann Cardiothorac Surg 2020 Mar;9(2):134-140

Division of Pediatric Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, WI, USA.

Though the Fontan circulation provides long-term palliation for patients with univentricular hearts, failure of the circulation may ensue, leaving heart transplantation as the only definitive treatment. For Fontan patients awaiting transplant, both "right-sided" and "left-sided" symptoms may be present and severe, hence, biventricular mechanical circulatory support may be indicated. This can be provided by implantation of the total artificial heart (TAH), a procedure which is performed slightly differently than in patients with biventricular hearts. Read More

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http://dx.doi.org/10.21037/acs.2020.03.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160629PMC

Total artificial heart and the hepatobiliary-GI systems.

Authors:
Robert M Cole

Ann Cardiothorac Surg 2020 Mar;9(2):131-133

Department of Cardiology, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.

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http://dx.doi.org/10.21037/acs.2020.03.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160634PMC

Quality of life and rehabilitation after total artificial heart.

Ann Cardiothorac Surg 2020 Mar;9(2):128-130

1Department of Biobehavioral Nursing and Health Informatics, School of Nursing, 2Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.21037/acs.2020.02.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160620PMC

An infectious disease perspective-is destination therapy a viable option for total artificial hearts?

Ann Cardiothorac Surg 2020 Mar;9(2):126-127

1Department of Infectious Disease, 2Cedars Sinai Comprehensive Transplant Center, Cedars Sinai, Los Angeles, CA, USA.

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http://dx.doi.org/10.21037/acs.2020.02.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160626PMC

Renal function after implantation of the total artificial heart.

Authors:
Keyur B Shah

Ann Cardiothorac Surg 2020 Mar;9(2):124-125

The Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.21037/acs.2020.03.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160630PMC

Total artificial heart: neurological complications.

Ann Cardiothorac Surg 2020 Mar;9(2):121-123

Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.21037/acs.2020.02.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160631PMC

Total artificial heart: patient selection and risk factors.

Ann Cardiothorac Surg 2020 Mar;9(2):118-120

Department of Thoracic and CardioVascular Surgery, Thorax Institut, University of Nantes, Nantes, France.

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http://dx.doi.org/10.21037/acs.2020.02.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160622PMC

Total artificial heart in patients with post-infarction ventricular septal defect.

Authors:
Igor D Gregoric

Ann Cardiothorac Surg 2020 Mar;9(2):116-117

Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.21037/acs.2020.01.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160633PMC

Application of total artificial heart in patients with primary malignant cardiac tumors-current treatment strategies.

Ann Cardiothorac Surg 2020 Mar;9(2):113-115

Division of Thoracic Transplantation & Mechanical Circulatory Support, Department of Surgery, Miller School of Medicine, University of Miami, Coral Gables, FL, USA.

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http://dx.doi.org/10.21037/acs.2020.02.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160619PMC

Antithrombotic therapy for patients with total artificial hearts.

Ann Cardiothorac Surg 2020 Mar;9(2):110-112

Advanced Heart Program, Banner University Medical Group, Phoenix, AZ, USA.

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http://dx.doi.org/10.21037/acs.2019.12.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160618PMC

The total artificial heart in pediatrics: outcomes in an evolving field.

Ann Cardiothorac Surg 2020 Mar;9(2):104-109

The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Background: The use of the SynCardia temporary total artificial heart (TAH-t) in adults has increased with time. The development of the smaller, 50 cc TAH-t has expanded the potential applications of the device in children. We sought to describe the evolving use of the TAH-t over time and describe outcomes in the current era. Read More

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http://dx.doi.org/10.21037/acs.2020.02.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160627PMC

Heart transplantation after SynCardia total artificial heart implantation.

Ann Cardiothorac Surg 2020 Mar;9(2):98-103

Clinic for Thoracic- and Cardiovascular Surgery, Heart and Diabetes Centre North Rhine Westphalia, Bad Oeynhausen, Germany.

Background: The SynCardia total artificial heart (TAH) is the only approved TAH device. This report summarizes our single-center experience with the SynCardia TAH with particular focus on the outcome after subsequent heart transplantation.

Methods: We retrospectively analysed the outcome of all transplanted SynCardia TAH patients at our center between 2001 and 2019 in comparison to transplanted left ventricular assist device (LVAD) and biventricular assist device (BVAD) patients and to transplanted patients without prior durable mechanical circulatory support (non-MCS). Read More

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http://dx.doi.org/10.21037/acs.2020.03.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160625PMC

The total artificial heart in patients with congenital heart disease.

Ann Cardiothorac Surg 2020 Mar;9(2):89-97

Department of Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Background: While ventricular assist devices (VADs) remain the cornerstone of mechanical circulatory support (MCS), the total artificial heart (TAH-t) has gained popularity for certain patients in whom VAD support is not ideal. Congenital heart disease (CHD) patients often have barriers to VAD placement due to anatomic and physiological variation and thus can benefit from the TAH-t. The purpose of this study is to analyze the differences in TAH application and outcomes in patients with and without CHD. Read More

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http://dx.doi.org/10.21037/acs.2020.02.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160623PMC

Total artificial heart: surgical technique in the patient with normal cardiac anatomy.

Ann Cardiothorac Surg 2020 Mar;9(2):81-88

Advanced Heart Program, Banner University Medical Group, Phoenix, Arizona, USA.

Heart failure is a complex, growing problem with significant morbidity and mortality. Though heart transplantation remains the gold standard treatment for end-stage heart failure, there remains a national shortage of donor hearts. Mechanical circulatory support has provided an additional option for clinicians to support patients for the purposes of bridging patients to transplantation or to be used for destination therapy purposes. Read More

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http://dx.doi.org/10.21037/acs.2020.02.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160624PMC

Comparison of SynCardia total artificial heart and HeartWare HVAD biventricular support for management of biventricular heart failure: a systematic review and meta-analysis.

Ann Cardiothorac Surg 2020 Mar;9(2):69-80

Division of Cardiac Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Background: The aim of this study was to compare the outcomes of patients undergoing SynCardia total artificial heart (TAH) and biventricular HeartWare ventricular assist device (Bi-HVAD) support for biventricular heart failure (HF).

Methods: Electronic search was performed to identify all relevant studies detailing patients who underwent biventricular assist device implantation using Bi-HVAD devices and those who underwent TAH placement for biventricular HF. Twelve studies including 512 patients in the TAH group versus 38 patients in the Bi-HVAD group were pooled for meta-analysis. Read More

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http://dx.doi.org/10.21037/acs.2020.03.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160621PMC

Cardiac replacement: total artificial heart.

Ann Cardiothorac Surg 2020 Mar;9(2):68

Departments of Surgery and Medicine, Banner UMC Phoenix, Banner-University of Arizona, Phoenix, AZ, USA.

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http://dx.doi.org/10.21037/acs.2020.02.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160628PMC

Sternotomy for lung transplantation: a description of technique.

Ann Cardiothorac Surg 2020 Jan;9(1):65-67

Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.21037/acs.2020.01.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049549PMC
January 2020

Sternotomy versus thoracotomy lung transplantation: key tips and contemporary results.

Ann Cardiothorac Surg 2020 Jan;9(1):60-64

Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.

The purpose of this report is to provide an updated description of the technique of bilateral sequential lung transplant via median sternotomy. A sternotomy provides the advantage of less morbidity than the clamshell incision, as well as exposure to perform mechanical circulatory support and concurrent cardiac procedures. Our experience shows that lung transplantation via a midline sternotomy can be done with equivalent to better short-term outcomes than a clamshell incision, including earlier extubation and fewer transfusions. Read More

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http://dx.doi.org/10.21037/acs.2020.01.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049548PMC
January 2020

Long tracheal replacement or the philosopher's stone.

Ann Cardiothorac Surg 2020 Jan;9(1):58-59

Department of Cardiovascular Surgery, ICCV, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.21037/acs.2019.11.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049555PMC
January 2020

Donor directed lobar lung transplantation.

Ann Cardiothorac Surg 2020 Jan;9(1):56-57

Trillium Health Partners, Mississauga, Ontario, Canada.

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http://dx.doi.org/10.21037/acs.2019.11.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049557PMC
January 2020

DCD lungs: is it all the same?

Ann Cardiothorac Surg 2020 Jan;9(1):54-55

Department of Thoracic Surgery, ICR. Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.21037/acs.2019.11.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049554PMC
January 2020

Addressing donor-organ shortages using extended criteria in lung transplantation.

Ann Cardiothorac Surg 2020 Jan;9(1):49-50

Trillium Health Partners, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.21037/acs.2019.10.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049552PMC
January 2020

The impact of hepatitis C viremic donor lung allograft characteristics on post-transplantation outcomes.

Ann Cardiothorac Surg 2020 Jan;9(1):42-48

Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Background: There is a low utilization rate of donated donor lungs. Historically, transplantation of lungs from hepatitis C-viremic donors to hepatitis C (HCV) negative recipients was avoided due to concern for worse graft survival. In the past few years with the advent of direct acting antiviral (DAA) therapy, there are emerging data suggesting the safety and efficacy of transplanting thoracic organs from HCV-viremic donors. Read More

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http://dx.doi.org/10.21037/acs.2020.01.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049551PMC
January 2020

Contemporary approaches in the use of extracorporeal membrane oxygenation to support patients waiting for lung transplantation.

Authors:
Steven P Keller

Ann Cardiothorac Surg 2020 Jan;9(1):29-41

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

The introduction of the lung allocation score in 2005 prioritized patients with decreased transplant-free survival as the recipients of donor organs and effectively increased the number of critically-ill patients with end-stage lung disease waiting for transplantation. This change presented transplant programs with the challenge of how to both extend the lives of critically-ill, end-stage lung disease patients waiting for donor organs and maintain patient vitality to survival through the rigors of surgery and post-transplant recovery. Motivated by the dismal outcomes of patients maintained on mechanical ventilation pre-transplant, transplant centers increasingly deploy extracorporeal membrane oxygenation (ECMO) as a means of supporting patients with advanced disease as a bridge to successful lung transplantation. Read More

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http://dx.doi.org/10.21037/acs.2019.12.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049559PMC
January 2020