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    8091 results match your criteria Annals of Ophthalmology Vestnik Oftalmologii [Journal]

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    [Anti-VEGF therapy resistance in neovascular age-related macular degeneration].
    Vestn Oftalmol 2017 ;133(4):103-108
    Eyesight Recovery Center, 11 A, B, Rossolimo St., Moscow, Russia, 119021.
    With account to the increase in the elderly population in most of the developed countries, the WHO defines age-related macular degeneration (AMD) as one of the main causes of blindness in the world. A large percentage of disability is accounted for by exudative, or neovascular, form of AMD. Today, a total of 5 anti-VEGF drugs exist that are recommended for treatment of exudative AMD: pegaptanib, ranibizumab, bevacizumab, aflibercept, and conbercept. Read More

    [Hybrid (femtosecond laser-assisted) phaco surgery and the state of the macula].
    Vestn Oftalmol 2017 ;133(4):97-102
    Research Institute of Eye Disease, 11 A,B, Rossolimo St., Moscow, Russia, 119021.
    The review covers different aspects of the impact of femtosecond laser-assisted cataract surgery on the state of the macular zone of the retina. Literature search has revealed inconsistency of the published data and indicated the need for a more detailed study of this problem. Read More

    [Influence of TGF-β cytokine and a number of other biochemical factors on regenerative process].
    Vestn Oftalmol 2017 ;133(4):89-96
    Research Institute of Eye Diseases, 11, A, B, Rossolimo St., Moscow, Russia, 119021.
    Scarring is one of the main causes of surgical failure in a number of eye diseases, dacryologic conditions in particular. The process of wound healing, including postoperative wound healing, goes through several stages mediated by various biochemical factors, such as growth factors and pro- and anti-inflammatory cytokines. The balance between the latter directly influences the wound healing. Read More

    [Morphological and clinical aspects of anterior capsulotomy in femtosecond laser-assisted cataract surgery].
    Vestn Oftalmol 2017 ;133(4):83-88
    First Moscow State Medical University, 2 str. 4 Bol'shaya Pirogovskaya St., Moscow, Russia, 119991.
    The review covers morphological and clinical aspects of femtosecond laser-assisted anterior capsulotomy in cataract surgery. Literature data suggests that femtosecond laser-assisted capsulotomy is more accurate in size, shape, and centration than manual. Femtosecond laser-assisted anterior capsulotomy improves the accuracy of IOL positioning within the capsular bag. Read More

    [Mixed infections and inflammatory ophthalmic diseases: clinical and laboratory observations].
    Vestn Oftalmol 2017 ;133(4):74-82
    Herpes clinic Ltd., 21B Michurinskiy prospekt, Moscow, Russia, 119192.
    In recent years, all medical specialists, including ophthalmologists, have been facing the problem of mixed infections. Recurrent inflammation in the anterior and posterior eye segments is often a result of infection by more than one variety of pathogens.

    Material And Methods: Over the period 2013-2016, 34 patients (14 men and 20 women) with different inflammatory processes in the eye who appeared DNA-positive for mycoplasmas (Mycoplasma hominis, Ureaplasma urealyticum) and/or chlamydiae (Chlamydia trachomatis) (PCR testing of tear fluid and/or urine) were followed up. Read More

    [Severe bilateral pseudomonas sclerokeratitis in comatose patient (clinical case)].
    Vestn Oftalmol 2017 ;133(4):68-73
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russia, 119021.
    The article presents a clinical case of severe bilateral pseudomonas sclerokeratitis in a patient with occlusion hydrocephalus and intracranial hypertension, who was in a coma and on a ventilator for 20 days. At first examination (7 days after the onset of purulent keratitis, during which the process had been rapidly progressing), the clinical picture included lagophthalmos, severe purulent corneal ulcer, bilateral purulent scleromalacia, perforated cornea in the left eye. On the same day, in order to maintain eye integrity, urgent reconstructive penetrating sclerokeratoplasty with subsequent sclerocorneal coating was performed in both eyes right in the intensive care unit. Read More

    [Peripheral corneal cross-linking (P-CXL) for ultrathin corneas with severe keratoconus: a new technique].
    Vestn Oftalmol 2017 ;133(4):65-67
    Abbondanza Eye Centers, 58 Via Luigi Bodio, Rome, Italy, 00191.
    Corneal cross-linking (CXL) is aimed at halting the progression of keratoconus and is widely considered to be the golden standard in its treatment. It is usually contraindicated, however, in patients with corneal thickness of less than 400 µm, leaving the ophthalmic surgeon no option, but to perform transepithelial CXL (epi-on), usually regarded as less effective. We report a novel approach for ultrathin corneas with severe keratoconus - peripheral corneal cross-linking (P-CXL), in which corneal epithelium is still removed but the apex of the cornea is left untouched. Read More

    [Diagnostic imaging for sclerochoroidal calcifica-tion].
    Vestn Oftalmol 2017 ;133(4):55-64
    Research Institute of Eye Diseases, 11, A, B, Rossolimo St., Moscow, Russia, 119021.
    The article presents two clinical cases of sclerochoroidal calcification. This is a rare benign condition that usually does not display itself and is only occasionally diagnosed. It can also be accompanied by systemic disorder of mineral metabolism. Read More

    [Multi-level analysis of the prevalence of pseudoexfoliative syndrome and pseudoexfoliative glaucoma].
    Vestn Oftalmol 2017 ;133(4):47-54
    Novosibirsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Kolkhidskaya St., Novosibirsk, Russia, 630096.
    Epidemiological investigation of pseudoexfoliative syndrome (PEX) as a glaucoma predictor is necessary for antiglaucoma treatment planning.

    Aim: To study the prevalence of PEX and pseudoexfoliative glaucoma (PXFG) among healthy people, naïve patients, and patients under observation as well as to evaluate the hypotensive efficacy of bimatoprost/timolol fixed combination (FCBT) over 4 months in PXFG.

    Material And Methods: Epidemiological analysis, ophthalmological examination, statistical analysis. Read More

    [Combination treatment for cataract and glaucoma].
    Vestn Oftalmol 2017 ;133(4):42-46
    Peoples' Friendship University of Russia, Department of Ophthalmology, 15 Bakinskaya St. Moscow, Russia, 115516.
    Aim: To develop a new combination treatment for cataract and glaucoma that would involve drainage of the suprachoroidal space with an autoscleral flap and to assess the outcomes of patients who underwent combined phacoemulsification and non-penetrating deep sclerectomy with suprachoroidal drainage with an autoscleral flap.

    Material And Methods: We have studied the results of combination surgical treatment of cataract and glaucoma performed in 34 patients (34 eyes), notably phacoemulsification and non-penetrating deep sclerectomy with suprachoroidal drainage.

    Results: In the early postoperative period, visual acuity ranged from 0. Read More

    [АComparative analysis of the magnitude of the distance and lens-induced objective accommodative response in patients with different refraction].
    Vestn Oftalmol 2017 ;133(4):37-41
    Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russia, 105062.
    Aim: To study the magnitude of objective accommodative response (OAR) with account to the method of image defocusing. The latter can be realized by bringing the object nearer to the eye or by adding a minus lens in front of the viewer.

    Material And Methods: We examined 63 patients (126 eyes) with different refraction aged from 7 to 31 years. Read More

    [Changes in biomechanical properties of the ocular fibrous tunic in patients with primary open-angle glaucoma in response to drug-induced stress-relief tests].
    Vestn Oftalmol 2017 ;133(4):31-36
    I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya St., Moscow, Russia, 119991.
    Aim: To determine the effect of drug-induced stress-relief tests on biomechanical properties of the ocular fibrous tunic in eyes with early, moderate, or advanced primary open-angle glaucoma (POAG).

    Material And Methods: A total of 202 eyes of 150 patients with POAG of different severity (early, moderate, or advanced) and 36 eyes of 30 healthy controls were examined. The mean patient age was 62±8. Read More

    [Structural retinal and optic nerve changes in patients with post-geniculate visual pathway damage].
    Vestn Oftalmol 2017 ;133(4):25-30
    Research Institute of Eye Diseases, 11 A,B, Rossolimo St., Moscow, Russian Federation, 119021.
    Aim: To establish the possibility of retrograde trans-synaptic neural degeneration following acquired post-geniculate visual pathway damage.

    Material And Methods: Twenty-two patients with homonymous hemianopia caused by acquired post-geniculate visual pathway damage were examined. Peripapillary retinal nerve fiber layer (RNFL) thickness and ganglion cell complex (GCC) measurements were assessed with RTVue-100 Fourier-domain optical coherence tomography (OCT). Read More

    [Heidelberg retinal tomography of the optic disc in the early diagnosis of glaucoma].
    Vestn Oftalmol 2017 ;133(4):17-24
    Tambov branch of S. Fyodorov Eye Microsurgery Federal State Institution, 1 Rasskazovskoe shosse, Tambov, Russian Federation, 392000; Tambov State University named after G.R. Derzhavin, Medical Institute, 93 Sovetskaya St., Tambov, Russian Federation, 392000.
    Aim: To analyze anatomical and topographic optic disc parameters with account to the disc area in glaucoma suspects.

    Material And Methods: The study included 302 patients (408 eyes) aged 25 to 76 years (the mean age of 50.5±12. Read More

    [Specific immunoglobulins G and M in blood serum in retinoblastoma and 'pseudoretinoblastoma'].
    Vestn Oftalmol 2017 ;133(4):12-16
    Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russia, 105062.
    Perinatal inflammatory retinal diseases and intrauterine retinal maldevelopments are mistaken for retinoblastoma as often as in 8-16% of cases.

    Aim: To analyze the infectious status in children with retinoblastoma and pseudoretinoblastoma at different ages.

    Material And Methods: A total of 47 retinoblastoma suspects aged 4-69 months were enrolled. Read More

    [Molecular genetic diagnosis of Stargardt disease].
    Vestn Oftalmol 2017 ;133(4):4-11
    Research Centre of Medical Genetics, 1 Moskvorech'e St., Moscow, Russia, 115478.
    Aim: To comparatively evaluate the efficacy of genetic screening in patients with Stargardt disease (SD) by using an express panel of 5 most common ABCA4 mutations and performing massive parallel sequencing of all coding regions of the ABCA4, ELOVL4, PROM1, and CNGB3 genes.

    Material And Methods: MLPA analysis for 5 ABCA4 mutations, namely p.G863A, p. Read More

    [Atropine use for progressive myopia in children and adolescents].
    Vestn Oftalmol 2017 ;133(3):89-98
    Moscow Helmholtz Research Institute of Eye Diseases, Ministry of Health of Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russia, 105062.
    The worldwide prevalence of myopia varies within the range of 20-50% among the adult population of Europe and the United States reaching 60-90% in Asian countries. Reduction of pediatric myopia rates is an important task of medicine. From many reported conservative methods for stabilization of myopia, those that involve pharmaceutical measures are worth paying attention to. Read More

    [n.s.i.n.i.V. Biomechanical aspects of anterior capsulotomy in cataract surgery].
    Vestn Oftalmol 2017 ;133(3):82-88
    Bauman Moscow State Technical University, 5/12-aya Baumanskaya, Moscow, Russia, 105005.
    This paper reviews studies on biomechanical properties of the anterior lens capsule. Early experiments in this field were more fundamental. Later studies were aimed mainly at assessing the mechanical stability of the capsule edge after manual or femtosecond laser capsulorhexis (capsulotomy) - an important step in modern minimally invasive phaco surgery. Read More

    [Influence of vascular endothelial growth factor on angiogenesis and neurogenesis].
    Vestn Oftalmol 2017 ;133(3):75-81
    Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021.
    Vascular endothelial growth factor (VEGF) is known as a key mediator of angiogenesis, but there is also evidence of its broad significance in neurogenesis and neuroprotection. Cytokines of the VEGF family affect neovascularization and neural development in the brain, particularly during cerebral ischemia, in which there is a coordinated interaction of angiogenesis and neurogenesis that contributes to rapid functional recovery. This review examines the involvement of VEGF family members and their receptors in physiological and pathophysiological processes as well as the relationship between VEGF-A plasma levels and ischemic stroke. Read More

    [Current approach and the role of laser photocoagulation in the treatment of retinal vein occlusions].
    Vestn Oftalmol 2017 ;133(3):67-74
    Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021.
    Despite the emergence of new approaches in the treatment of retinal vein thrombosis and post-thrombotic complications, namely, intravitreal pharmacotherapy and surgical treatment, laser photocoagulation continues to play a significant role in the management of patients with this pathology. Although the method of laser photocoagulation has been used for quite a long time, different views exist on its indications and execution in specific clinical situations. At that, not all opinions regarding the use of laser photocoagulation in thrombosis are based on convincing clinical studies. Read More

    [Results of corneal crosslinking for pellucid marginal corneal degeneration].
    Vestn Oftalmol 2017 ;133(3):58-66
    Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan, 90 Pushkin St., Ufa, Russia, 450008.
    Aim: to evaluate the clinical effectiveness of crosslinking in patients with progressive pellucid marginal corneal degeneration (PMCD).

    Material And Methods: A total of 9 patients (16 eyes) with progressive PMCD were treated by standard crosslinking. The cornea was saturated with Dextralink solution and UV-A irradiated at 3 mW/cm2 for 30 minutes. Read More

    [Surgical treatment of rhegmatogenous retinal detachments with high risk of proliferative vitreoretinopathy].
    Vestn Oftalmol 2017 ;133(3):51-57
    National Centre of Ophthalmology named after acad. Zarifa Aliyeva, 32/15 Javadkhan St., Baku, Azerbaijan, AZ 1114.
    Aim: to analyze the effect of internal limiting membrane (ILM) peeling in patients undergoing 23-gauge pars plana vitrectomy for the treatment of rhegmatogenous retinal detachment (RRD) with a high risk of proliferative vitreoretinopathy (PVR).

    Material And Methods: This was a prospective consecutive study of 231 eyes of 227 patients. All eyes underwent vitrectomy with silicone oil/gas tamponade for RRD with a high risk of PVR: in 42 eyes the ILM was peeled (group 1) and in the remaining 189 eyes - was not (group 2). Read More

    [Effect of medicinal treatment on epithelial wound healing after phacoemulsification].
    Vestn Oftalmol 2017 ;133(3):44-50
    Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslava Gasheka St., Saint Petersburg, Russia, 192283.
    Aim: to compare the dynamics of epithelial wound healing under two different post-op treatments in patients after uncomplicated phacoemulsification.

    Material And Methods: This prospective randomized clinical trial included 40 eyes of 40 patients aged 66.4±8. Read More

    [Significance of anti-myelin basic protein antibodies for ocular hydrodynamic disturbances in primary open-angle glaucoma].
    Vestn Oftalmol 2017 ;133(3):37-43
    Clinical Hospital named after N.A. Semashko, 3 Semashko St., Ryazan, Russia, 390005.
    The aim of the study was to investigate the significance of anti-myelin basic protein (MBP) antibodies (AB) for ocular hydrodynamic disturbances in primary open-angle glaucoma (POAG). The study was conducted using the enzyme-linked immunosorbent assay (ELISA). The patients included had either high-tension (82 cases), or normal-tension (62 patients) glaucoma (HTG and NTG). Read More

    [Analysis of corneal biomechanical changes after femtosecond laser-assisted laser in situ keratomileusis in children with hyperopic anisometropia].
    Vestn Oftalmol 2017 ;133(3):30-36
    Cheboksary branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Traktorostroiteley St., Cheboksary, Chuvash Republic, Russia, 428000.
    Aim: to analyze corneal hysteresis (CH) and corneal resistance factor (RF) readings obtained with the Reichert Ocular Response Analyzer (ORA) before and after hyperopic femtolaser-assisted laser in situ keratomileusis (FS-LASIK) in children with anisometropia as well as to establish factors that may cause changes in these parameters.

    Material And Methods: CH and RF were evaluated before and 1.5 years after FS-LASIK performed on amblyopic eyes of 28 patients aged 6-14 years. Read More

    [Electrophysiological studies of the retina in antiphospholipid syndrome].
    Vestn Oftalmol 2017 ;133(3):22-29
    Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russia, 119021.
    Aim: to evaluate the functional state of the retina in patients with antiphospholipid syndrome (APS) through different types of electroretinography (ERG).

    Material And Methods: The total ERG (t-ERG), local macular ERG (m-ERG), and oscillatory potentials (OP) were recorded in 56 patients with verified APS.

    Results: In most patients with APS, ERG was of abnormal appearance, particularly, t-ERG was notable for reliably lower a- and b-wave amplitudes (70% of cases), m-ERG - for lower amplitudes and shorter latency (64% of cases). Read More

    [Microcirculatory blood and lymph flow examination in eyelid skin by laser Doppler flowmetry].
    Vestn Oftalmol 2017 ;133(3):16-21
    Research Institute of Eye Diseases 11 A, B Rossolimo St., Moscow, Russia, 119021.
    Aim: to study normal blood and lymph microcirculation of the upper and lower eyelids in different age groups.

    Material And Methods: The study included 108 volunteers (216 eyes) aged from 20 to 80 years with no signs of changes in anterior segment structures, who were grouped by age ranges (20-30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, and 71-80 years) into 6 groups equal in gender and quantitative composition. In all volunteers, microcirculation of the upper and lower eyelids was examined by laser Doppler flowmetry (LDF) ('LASMA MC-1' peripheral blood and lymph flow analyzer and 'LASMA MC' laser diagnostic complex, LASMA LLC). Read More

    [Studying the association between genetic polymorphism of growth factors and the development of primary open-angle glaucoma].
    Vestn Oftalmol 2017 ;133(3):9-15
    Belgorod State University, 85 Pobedy St., Belgorod, Russia, 308015.
    Primary open-angle glaucoma (POAG) is a multifactorial disease, etiopathogenesis of which largely depends on growth factors. Possessing a variety of medical and biological effects, these cytokines may influence the development and progression of POAG.

    Aim: to reveal the role of genetic polymorphisms of growth factors in predisposition to developing POAG that is refractory to local hypotensive therapy. Read More

    [Comparative analysis of corneal aberrations after intrastromal segments and MyoRing implantation using femtosecond laser in patients with keratoconus].
    Vestn Oftalmol 2017 ;133(3):3-8
    Cheboksary branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Traktorostroiteley St., Cheboksary, Chuvash Republic, Russia, 428028.
    Aim: to comparatively analyze corneal aberrations after intrastromal corneal segments (ICS) and MyoRing implantation using femtosecond laser in patients with stage II-III keratoconus (KC) by Pentacam examination.

    Material And Methods: We have operated on 135 patients (145 eyes) with stage II or III KC. Depending on surgical technique, all patients were divided into two groups. Read More

    [Vascular endothelial growth factor inhibitors in the treatment of neovascular age-related macular degeneration].
    Vestn Oftalmol 2017 ;133(2):125-129
    Peoples' Friendship University of Russia, Medical Institute, Medical Faculty, Department of the Common and Clinical Pharmacology, 6 Miklukho-Maklaya St., Moscow, Russian Federation, 1171986.
    Neovascular age-related macular degeneration (AMD) is the leading cause of vision loss in older patients. An important role in angiogenesis is played by regulatory mechanisms (an increase in the number of proliferating endothelial and stromal cells and morphological alterations in the vascular network) induced by factors from the vascular endothelial growth factor (VEGF) family. Since 2006, the key treatment of neovascular AMD includes agents that inhibit the activity of VEGF. Read More

    [Etiopathogenesis of ocular ischemic syndrome].
    Vestn Oftalmol 2017 ;133(2):120-124
    Tashkent Institute of Postgraduate Medical Education, 51 Parkent St., Tashkent, Uzbekistan, 100009.
    Ocular ischemic syndrome (OIS) is a collection of symptoms of carotid and ophthalmic artery disease of common genesis accompanied by ischemia of eyeball membranes. Specifically, the intraocular blood flow becomes impaired due to inflow reduction or arrest, while the venous outflow remains patent. Causes of OIS include arterial hypertension, atherosclerosis, diabetes, aortoarteritis and other vascular diseases. Read More

    [Functional examinations of visual channels: clinical aspects].
    Vestn Oftalmol 2017 ;133(2):114-119
    Moscow Helmholtz Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.
    The review discusses literature data on the clinical relevance of functional assessment of magno- (M), parvo- (P), and koniocellular (K) pathways. It also covers the differential contribution of the M, P, and K channels to visual impairments and how it determines the prognosis, early diagnosis, and treatment choice in patients with neurodegenerative diseases of the retina and brain. Selective changes in the performance of the visual channels are investigated by the example of glaucoma and optic neuritis in multiple sclerosis (MS) patients. Read More

    [Morphological features of clinical manifestations of particular congenital lens and vitreous anomalies].
    Vestn Oftalmol 2017 ;133(2):104-113
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021; Sechenov First Moscow State Medical University, 8-2 Malaya Trubetskaya St., Moscow, Russian Federation, 119991.
    The review covers general clinical features of particular congenital anomalies of the human eye associated with its abnormal embryonic development. Principal literature sources on evaluation of congenital changes in the vitreous body and identification of its 'underdevelopment' in certain types of congenital cataracts have been studied. The said changes were analyzed with account to general pathology of the human body as well as local morphological manifestations. Read More

    [Atypical clinical case of solar retinopathy].
    Vestn Oftalmol 2017 ;133(2):99-103
    Khabarovsk branch of the Academician S.N. Fyodorov IRTC 'Eye Microsurgery', 211 Tikhookeanskaya St., Khabarovsk, Russian Federation, 680033; Far Eastern State Medical University, 35 Muravyeva-Amurskogo St., Khabarovsk, Russian Federation, 680000.
    The paper presents an atypical case of solar retinopathy after short-term exposure to reflected focused sunbeams. An ophthalmoscopic peculiarity was the presence of intraretinal hemorrhage. The basis for establishing the diagnosis were spectral optical coherence tomography and fluorescein angiography findings. Read More

    [Complex treatment results in a congenital glaucoma patient (case report)].
    Vestn Oftalmol 2017 ;133(2):92-98
    Tambov State University named after G.R. Derzhavin, 93 Sovetskaya St., Tambov, Russian Federation, 392000.
    Early diagnosis of congenital glaucoma allows surgery to be performed at the stage of reversible glaucomatous alterations of the optic disc and retina. In primary congenital glaucoma, the main reason for visual acuity reduction following surgical stabilization of the intraocular pressure are corneal changes. These include an increased corneal diameter, Haab's striae, areas of thickening and a greater posterior elevation. Read More

    [Combination therapy of refractory localized granulomatosis with polyangiitis and orbital involvement].
    Vestn Oftalmol 2017 ;133(2):86-91
    Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, 2, str. 4 Bol'shaya Pirogovskaya St., Moscow, Russian Federation, 119991.
    Granulomatous orbital cellulitis is one of the most common ocular manifestations of granulomatosis with polyangiitis (Wegener's). The process is often refractory to conventional immunosuppressive therapy and requires a more radical treatment approach. However, surgical experience with this type of patients is limited. Read More

    [Orbital case of ocular dirofilariasis].
    Vestn Oftalmol 2017 ;133(2):82-85
    Academician S.N. Fyodorov IRTC 'Eye Microsurgery', 59А Beskudnikovskiy bulvar, Moscow, Russian Federation, 127486.
    Aim: to report a clinical case of orbital dirofilariasis with attention to peculiarities of disease presentation, diagnostic measures, and treatment results.

    Material And Methods: A patient with a history of spontaneously subsiding recurrent oedema of the lower eyelid suspicious of parasitic cyst formation. The diagnosis was confirmed preoperatively by orbital ultrasound. Read More

    [New approaches to the treatment of keratoconjunctivitis sicca].
    Vestn Oftalmol 2017 ;133(2):75-81
    Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    A new method has been developed for the treatment of severe forms of keratoconjunctivitis sicca (KCS) that involves the use of an original cyclosporine A (CyA) saturated soft contact lens (SCL) together with preservative-free artificial tears therapy.

    Aim: to evaluate the effectiveness of the newly developed treatment for KCS based on the use of medical SCL saturated with 0.05% CyA. Read More

    [Features of psycho-emotional state of patients with central serous chorioretinopathy].
    Vestn Oftalmol 2017 ;133(2):70-74
    Irkutsk Branch of the Academician S.N. Fyodorov IRTC "Eye Microsurgery", 337 Lermontova St., Irkutsk, Russian Federation, 664033.
    Aim: to investigate peculiarities of psycho-emotional reactions in patients with central serous chorioretinopathy (CSCR).

    Material And Methods: The study involved 35 patients with CSCR (mean age of 47.7±8. Read More

    [Effectiveness of epithelialization therapy after surgical treatment of pterygiu].
    Vestn Oftalmol 2017 ;133(2):64-69
    Volgograd State Medical University, 1 Pavshikh bortsov Sq., Volgograd, Volgogradskaya Oblast, Russian Federation, 400131.
    Pterygium is widely distributed in regions with hot and dry climate. Frequent relapses of the disease are due to delayed epithelialization of postoperative corneal erosion, associated inflammation and formation of dry areas of the cornea. Effective stimulation of corneal epithelium regeneration in the postoperative period could reduce the frequency of relapses. Read More

    [Risk of senile cataract among nuclear industry workers].
    Vestn Oftalmol 2017 ;133(2):57-63
    Southern Urals Biophysics Institute, Federal Medical-Biological Agency of Russia, 19 Ozyorskoe shosse, Ozyorsk, Chelyabinsk Oblast, Russian Federation, 456780.
    Aim: to assess the relative risk (RR) of senile cataract in a cohort of workers occupationally exposed to external gamma-rays over a long time period.

    Material And Methods: The RR of cataract development was studied in a cohort of nuclear workers that were first employed in 1948-1982 and followed up till the end of 2008 (n=22,377; females, 25.4%). Read More

    [Influence of endothelial graft thickness on postoperative visual acuity].
    Vestn Oftalmol 2017 ;133(2):52-56
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Aim: to assess the influence of the endothelial graft thickness on postoperative visual acuity following modified endothelial keratoplasty (UTDSAEK).

    Material And Methods: The study included 49 patients with pseudophakic bullous keratopathy and no concomitant disorders of either the retina or optic nerve. Ultrathin Descemet's stripping automated endothelial keratoplasty (UTDSAEK) was performed in all cases. Read More

    [Ocular hypotensive effect of systemic beta-blockers in patients with primary glaucoma and arterial hypertension].
    Vestn Oftalmol 2017 ;133(2):46-51
    Novokuznetsk State Institute of Postgraduate Medicine, Ministry of Health of the Russian Federation, 5 Stroiteley prospekt, Novokuznetsk, Kemerovo Oblast, Russian Federation, 654005.
    Aim: to evaluate the ocular hypotensive efficacy of systemic beta-blockers in primary glaucoma patients suffering from arterial hypertension (AH).

    Material And Methods: The study included 29 patients with POAG (58 eyes) aged from 47 to 83 years. Patients with stage I-III POAG received instillations of prostaglandin analogs and carbonic anhydrase inhibitors. Read More

    [Cortisol levels in plasma and aqueous humour of patients with steroid induced and other glaucomas].
    Vestn Oftalmol 2017 ;133(2):39-45
    National Centre of Ophthalmology named after acad. Zarifa Aliyeva, 32/15 Javadkhan St., Baku, Azerbaijan, AZ 1114.
    The paper describes the role of endogenous glucocorticoids in the pathogenesis of open-angle glaucoma. As to steroid-induced glaucoma (SG), however, indicators of systemic and local cortisol metabolism are yet underinvestigated. Aim - to determine and compare systemic (plasma) and local (aqueous humour) cortisol concentrations in patients with SG and other types of glaucoma (OTG). Read More

    [Macular blood flow in glaucoma].
    Vestn Oftalmol 2017 ;133(2):29-38
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Aim: to assess macular blood flow in primary open-angle glaucoma (POAG) patients using optical coherence tomography angiography (OCT-A).

    Material And Methods: The study included 65 POAG patients and 22 age-matched healthy volunteers. Using OCT-A, blood flow parameters (Flow Area, Flow Index, and Vessel Density) were assessed in the para- and perifovea (0. Read More

    [Clinical evaluation of the effectiveness of cholinesterase inhibition with neuromidin in the treatment of primary glaucoma patients].
    Vestn Oftalmol 2017 ;133(2):22-28
    Voronezh City Clinical Hospital # 17, 36 Karla Marksa St., Voronezh, Russian Federation, 394036.
    Aim: to investigate neuromidin effectiveness in the treatment of patients with primary glaucoma and compensated intraocular pressure (IOP).

    Material And Methods: A total of 40 patients (80 eyes) were examined. Of them, 10 eyes with early glaucoma, 36 eyes with moderate-stage glaucoma, 33 eyes with advanced glaucoma, and 1 eye with end-stage glaucoma. Read More

    [Selective symptomatic therapy of macular edema due to occlusive processes in retinal venous system].
    Vestn Oftalmol 2017 ;133(2):18-21
    Ufa Eye Research Institute, 90 Pushkina St., Ufa, Russian Federation, 450008.
    Aim: to evaluate the effect of dexamethasone intravitreal implant on the functional state of the eye in macular edema associated with central retinal vein occlusion.

    Material And Methods: The study included two groups of patients: group 1 (control group) - 8 patients (16 eyes) without ocular pathology and group 2 (study group) - 8 patients (8 eyes) with macular edema on the background of newly diagnosed thrombosis of the central retinal vein. All the patients from the study group underwent insertion of an intravitreal dexamethasone implant - Ozurdex. Read More

    [OCT-morphometric and angiographic parallels between different variants of central serous chorioretinopathy].
    Vestn Oftalmol 2017 ;133(2):10-17
    Zrenie Eye Center LLC, 88 Komsomol'skiy prospekt, Chelyabinsk, Russian Federation, 454014.
    Central serous chorioretinopathy (CSCR) is a frequent cause of vision deterioration. Often it is associated with type 1 neovascularization under the pigment retinal epithelium (RPE). Optical coherence tomography angiography (OCT-angiography) enables non-invasive and contrast-free detection of neovessels in any retinal layer, which makes the method appropriate for diagnostics in CSCR. Read More

    [Wavefront aberrations and accommodation in myopes and hyperopes].
    Vestn Oftalmol 2017 ;133(2):5-9
    Moscow Helmholtz Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.
    Aim: to comparatively investigate accommodation, pseudoaccommodation, and higher-order aberrations in children and young adults with myopia and hyperopia.

    Material And Methods: A total of 39 myopic (the mean error of (-)5.2±1. Read More

    [To the history of ophthalmology clinic at the Moscow University].
    Vestn Oftalmol 2017;133(1):103-108
    National Research Institute of Public Health named after N.A. Semashko, 12-1 Voronthsovo pole St., Moscow, Russian Federation, 105064.
    This is the first time the process of organizing the Clinic of Eye Diseases at the Moscow University has been traced and systematized basing on archival documents and publications - from rendering three beds for ophthalmology patients within the surgical clinic in 1805 to the establishment of a separate department of ophthalmology and subsequent foundation of the Hospital Eye Clinic in the Devich'e pole (Virgin's field) district in 1892. Read More

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