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    11497 results match your criteria Annals of Ophthalmology [Journal]

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    [Axial ametropias of very high degree].
    Vestn Oftalmol 2018 ;134(2):109-111
    S. Fyodorov Eye Microsurgery Federal State Institution, 59 A Beskudnikovskiy Blvd., Moscow, Russian Federation, 127486.
    To characterize a complex of disorders developing in patients with extreme values of anteroposterior axis of the eye, it is necessary to create an appropriate nomenclature. As a topic for discussion, authors suggest to supplement the existing classifications of myopia and hyperopia with 'character of ametropia' section (axial, refractive, mixed) and the definition of ametropias of very high (ultra-high/extreme) degree (a criterion for myopia is: <-10 D). In prospect, classification of such ametropias should be based on the length of the anteroposterior axis of the eye. Read More

    [Extreme (complicated, ultra-high) refractive errors: terminological misconceptions!?]
    Vestn Oftalmol 2018 ;134(2):104-108
    Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, Chair of Ophthalmology, 2 b. 4 Bolshaya Pirogovskaya St., Moscow, Russian Federation, 119991.
    The article reviews development mechanisms of different refractive errors accompanied by marked defocus of light rays reaching the retina. Terminology used for such ametropias includes terms extreme, ultra-high and complicated. Justification of their usage for primary ametropias, whose symptom complex is based on changes in axial eye length, is an ongoing discussion. Read More

    [Intumescent cataract surgery].
    Vestn Oftalmol 2018 ;134(2):98-103
    Tambov branch of S. Fyodorov Eye Microsurgery Federal State Institution, 1 Rasskazovskoe shosse, Tambov, Russian Federation, 392000.
    Intumescent cataract surgery is one of the topical problems of ophthalmology. The article reviews methods of intumescent cataract diagnostics and structural features of swelling lens. Manual or femtolaser-assisted anterior continuous circular capsulorhexis and intumescent cataract phacoemulsification techniques require further research. Read More

    [Leber hereditary optic neuropathy].
    Vestn Oftalmol 2018 ;134(2):92-97
    University of Alberta, 116 St. and 85 Ave., Edmonton, AB, Canada, T6G 2R3.
    Leber hereditary optic neuropathy is characterized by bilateral, painless loss of vision in children and young adults (generally up to 25 years old). Since its first description in 1871, the understanding of its etiology and pathogenesis has improved considerably. The article considers Leber neuropathy from the points of view of ophthalmology, neurology and molecular genetics, and presents data on experimental treatment methods, one of which is undergoing clinical trial. Read More

    [Lymphatic system of the eye].
    Vestn Oftalmol 2018 ;134(2):86-91
    Novosibirsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Kolkhidskaya St., Novosibirsk, Russian Federation, 630096.
    Existence of lymphatic outflow of intraocular fluid is still an open question. Identification of the lymphatic capillaries and vessels in various human organs in normal and pathological conditions became possible with discovery of endotheliocyte markers for lymphatic vessels. However, the available information on the presence of lymphatic structures in the human eye is inconsistent and uncertain. Read More

    [Bioinorganic chemical composition of the lens and methods of its investigation].
    Vestn Oftalmol 2018 ;134(2):78-85
    I.M. Sechenov First Moscow State Medical University, 8/2 Malaya Trubetskaya St., Moscow, Russian Federation, 119991.
    Bioinorganic chemical composition of the lens of human and experimental animals (cows, dogs, rats, rabbits) have been analyzed in various studies. In most cases, the studies employed different methods to determine the gross (total) composition of chemical elements and their concentrations in the examined samples. Less frequently, they included an assessment of the distribution of chemical elements in the lens and correlation of their concentration with its morphological changes. Read More

    [Spontaneous separation of secondary epiretinal membrane].
    Vestn Oftalmol 2018 ;134(2):73-77
    Volga District Medical Centre, Federal Medical and Biological Agency, 2 Nizhnevolgskaya Naberegnaya, Nizhny Novgorod, Russian Federation, 603001; Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Sq., Nizhny Novgorod, Russian Federation, 603005.
    The article presents a rare clinical case of secondary epiretinal membrane (ERM) in a 67-years-old woman. The patient was diagnosed with ERM in the left eye after loss of vision complaints. One year prior to the visit the patient had underwent 2 sessions of laser photocoagulation for proliferative post-thrombotic retinopathy in the left eye. Read More

    [New visual field testing possibilities (a preliminary report)].
    Vestn Oftalmol 2018 ;134(2):66-72
    Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
    There are currently no portable mobile perimeters that allow visual field testing outside ophthalmologist's examination rooms.

    Purpose: To develop a mobile perimetry technique based on use of a virtual reality headset (VR).

    Material And Methods: The study involved 26 patients (30 eyes) with II-III stage primary open-angle glaucoma (POAG) with compensated IOP. Read More

    [Effects of artificial tears on ocular surface in glaucomatous patients with long-term instillation of preserved antiglaucoma eye drops].
    Vestn Oftalmol 2018 ;134(2):59-65
    Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
    Purpose: To study the effects of long-term instillation of 0.18% sodium hyaluronate artificial tears VISMED multi on ocular surface in glaucomatous patients with long-term instillation of preserved anti-glaucoma drops.

    Material And Methods: The study included 79 patients (40 female and 39 male; 79 eyes in total) with primary open-angle glaucoma (POAG) divided into 3 groups according to disease stage: mild or early (stage I) glaucoma - 15 patients (15 eyes), moderate (stage II) glaucoma - 30 patients (30 eyes), advanced or severe (stage III) glaucoma - 34 patients (34 eyes). Read More

    [Selection of optimal method of general anesthesia for intubation of nasolacrimal duct in young children].
    Vestn Oftalmol 2018 ;134(2):53-58
    Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaya St., Khabarovsk, Russian Federation, 680033.
    Purpose: comparative assessment of safety and clinical efficacy of Sevoflurane and Halothane in general anesthesia for nasolacrimal duct intubation in children.

    Material And Methods: Clinical results of nasolacrimal duct intubation in 288 children with persistent obstruction of tear duct were analyzed. A newly developed method of general anesthesia in the supine position was used for all cases. Read More

    [Exophthalmometry with computed tomography].
    Vestn Oftalmol 2018 ;134(2):48-52
    S. Fyodorov Eye Microsurgery Federal State Institution, 59 А Beskudnikovsky Blvd., Moscow, Russian Federation, 127486.
    Bone abnormalities of orbit seen in patients with trauma or radiolesion are accompanied by enophthalmos or exophthalmos. Conventional measurements of eyeball protrusion with Hertel's exophthalmometer or with computed tomography do not provide accurate and reliable data, especially in patients with asymmetry of lateral orbital rims.

    Purpose: To develop a method of computed exophthalmometry that provides accurate and reliable measurements in patients with various orbital conditions. Read More

    [Transepithelial corneal collagen crosslinking in patients with progressive keratoconus].
    Vestn Oftalmol 2018 ;134(2):42-47
    Medical Academy named after S.I. Georgievsky of Vernadsky CFU, 5/7 Lenin Avenue, Simferopol, Republic of Crimea, Russian Federation, 295051.
    Purpose: To assess the effectiveness of transepithelial collagen crosslinking (CXL) in patients with keratoconus.

    Material And Methods: The study involved 44 patients (44 eyes) with stage I-II progressive keratoconus. Patients were divided into two groups. Read More

    [Morphological changes of cornea in children with hyperopia in the immediate and remote postoperative period after laser keratomieleusis according to confocal microscopy data].
    Vestn Oftalmol 2018 ;134(2):32-41
    Cheboksary branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Traktorostroiteley Pr., Cheboksary, Chuvash Republic, Russian Federation, 428028.
    Studying morphological changes of cornea in the remote postoperative period is becoming increasingly relevant with refractive surgeries being adapted for children.

    Purpose: comparative analysis of keratocyte density and hystomorphologic changes of cornea after laser in situ keratomieleusis (LASIK) and femtosecond laser-assisted LASIK (FS-LASIK) in children with hyperopia.

    Material And Methods: 109 patients aged 6-17 years in 2 groups were examined with 'Confoscan-4' confocal microscope. Read More

    [Prediction of activity and severity of endocrine ophthalmopathy by multidimensional linear regression modeling].
    Vestn Oftalmol 2018 ;134(2):23-31
    State Research Center of Preventive Medicine, Ministry of Health of the Russian Federation, 10 building 3 Petroverigsky per., Moscow, Russian Federation, 101990.
    Endocrine ophthalmopathy (EOP) is a severe chronic autoimmune disease associated with autoimmune thyroid pathology that leads to loss of sight, cosmetic defects and quality of life decrease. EOP is difficult to give prognosis for due to various factors affecting its course and outcome.

    Purpose: To develop a reliable and precise prognosis method for EOP activity and severity based on personalized combination of risk factors in specific patients by multidimensional linear regression modeling. Read More

    [Anti-VEGF therapy for diabetic macular edema. From theory to clinical practice].
    Vestn Oftalmol 2018 ;134(2):12-22
    Novosibirsk State Regional Clinical Hospital, 130 Nemirovicha-Danchenko St., Novosibirsk, Russian Federation, 630008; Novosibirsk State Region University, 52 Krasny Prospect, Novosibirsk, Russian Federation, 630091.
    Purpose: To evaluate clinical effectiveness of aflibercept therapy for patients with diabetic macular edema (DME) - both naïve to the drug and unresponsive to previous anti-VEGF treatment.

    Material And Methods: The study included 127 patients (127 eyes) divided into two groups. The first group consisted of 100 primary DME patients (100 eyes) with mean age of 68. Read More

    [Influence of chemical compositions of anterior chamber aqueous humour and blood serum on the secretion of intraocular fluid].
    Vestn Oftalmol 2018 ;134(2):4-11
    Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
    Purpose: to identify the standard chemical composition of anterior chamber aqueous humour (AH) using energy dispersive spectrometer (EDS) integrated in scanning electron microscope (SEM); to study the influence of concentration gradient of chemical elements between aqueous humor and blood serum (BS) on the secretion of intraocular fluid (IOF) at normal and increased intraocular pressure (IOP).

    Material And Methods: The study involved two groups of patients consisting of 33 people (33 eyes) each. The 1 group included patients with cataract and normal IOP (control), the 2 group included patients with POAG and decompensated IOP. Read More

    [Ivan Nikolaevich Katsaurov - a distinguished Russian ophthalmologist].
    Vestn Oftalmol 2018 ;134(1):113-117
    National Research Institute of Public Health named after N.A. Semashko, 12-1 Voronthsovo pole St., Moscow, Russian Federation, 105064.
    Through archival documents and published sources, we have traced the rise of I.N. Katsaurov, an outstanding Russian ophthalmologist, and appraised his contribution to the development of ophthalmology. Read More

    [Pathogenesis and diagnostics of postsurgical macular edema].
    Vestn Oftalmol 2018 ;134(1):107-112
    Research Institute of Eye Diseases, Rossolimo St., 11 A, B, Moscow, Russian Federation, 119021.
    Postsurgical macular edema, known as Irvine-Gass syndrome, is one of the possible causes of reduced visual acuity in phaco surgery. The literature review provides summarized data on pathogenesis, risk factors, clinical manifestations, classification and basic approaches to diagnosis based on modern techniques. Read More

    [Epidemiology of keratoconus in different countries].
    Vestn Oftalmol 2018 ;134(1):104-106
    National Centre of Ophthalmology named after acad. Zarifa Aliyeva, 32/15 Javadkhan St., Baku, Azerbaijan, AZ 1114.
    The scientific problem of epidemiology of keratoconus in different countries is covered in the article. The results of original studies were analyzed and a conclusion has been drawn that keratoconus is quite a common disease in the world. Read More

    [Mechanical dilation of the pupil and its possible applications in femtosecond laser-assisted cataract surgery].
    Vestn Oftalmol 2018 ;134(1):97-103
    S. Fyodorov Eye Microsurgery Federal State Institution, Beskudnikovsky Blvd., 59А, Moscow, Russian Federation, 127486.
    In certain cases intraoperative pupil dilation during cataract surgery may be necessary to improve the visualization of intraocular structures and assure the atraumatic nature of surgical manipulations. The article reviews a wide range of pupil expanders, their historical aspects and possibilities of their application in modern cataract surgery. Read More

    [Juvenile xanthogranuloma of the eye].
    Vestn Oftalmol 2018 ;134(1):89-96
    Kemerovo Regional Clinical Ophthalmological Hospital, Oktyabrsky pr., 22А, Kemerovo, Russian Federation, 650066.
    Juvenile xanthogranuloma (JX) is a benign growth of fibrohistiocytoma range that mainly affects children. The most frequent localization of the tumor is skin integument. Non-cutaneous forms of JX are found in 5-10% of cases; they are manifested as deep lesions of soft tissues, involvement of various organs (oropharynx, lungs, liver, spleen, pericardium, gastrointestinal tract, central nervous system, bone marrow) including the organ of vision. Read More

    [Surgical treatment of pterygium].
    Vestn Oftalmol 2018 ;134(1):85-88
    Volgograd State Medical University, Pavshikh bortsov Sq., 1, Volgograd, Russian Federation, 400131.
    Pterygium is one of the modern problems of ophthalmology. The exact etiology and pathogenesis of this disease has not been reliably established and, as a result, there is no universal method for its recurrence-free treatment. The literature data on various methods of pterygium surgical treatment such as 'bare sclera', conjunctival autograft, limbal stem cells transplantation techniques, amniotic membrane plasty and other methods was analyzed. Read More

    [Differential diagnosis and treatment of Chandler iridocorneal endothelial syndrome].
    Vestn Oftalmol 2018 ;134(1):77-84
    Novosibirsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Kolkhidskaya St., Novosibirsk, Russian Federation, 630071.
    The article presents a profound clinical, instrumental and morphological analysis of a family case of iridocorneal endothelial syndrome (Chandler syndrome) notable for atypical aggressive bilateral course and unusual hereditary manifestation. Five stages of the pathological process have been suggested. Read More

    [Radio-wave surgery in the treatment of dacryocystitis].
    Vestn Oftalmol 2018 ;134(1):70-76
    Helmholtz Moscow Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.
    By improving the existing surgical technologies for dacryocystitis, one enhances the effectiveness of patient rehabilitation.

    Aim: To evaluate the effectiveness of radio-wave surgery in the treatment of dacryocystitis and lacrimal sac abscesses.

    Material And Methods: The clinical group consisted of 207 patients ranging in age from 7 to 89 years (the mean age of 41±7. Read More

    [Effect of internal limiting membrane peeling on morpho-functional state of the retina in patients with proliferative diabetic retinopathy (preliminary report)].
    Vestn Oftalmol 2018 ;134(1):63-69
    Ufa Eye Research Institute, 90 Pushkin St., Ufa, Republic of Bashkortostan, Russian Federation, 450008.
    Purpose: To compare morpho-functional parameters of retina during vitrectomy with and without internal limiting membrane (ILM) peeling in patients with proliferative diabetic retinopathy.

    Material And Methods: The study included 55 patients (55 eyes) that had underwent vitreoretinal surgery in the setting of antivasoproliferative therapy for proliferative diabetic retinopathy. Patients of the 1 group (n=27) underwent vitrectomy with silicone tamponade, 2 group (n=28) received similar treatment with the addition of ILM peeling. Read More

    [Evaluation of YAG-laser vitreolysis effectiveness based on quantitative characterization of vitreous floaters].
    Vestn Oftalmol 2018 ;134(1):56-62
    Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
    Purpose: To develop methods for evaluating effectiveness of YAG-laser vitreolysis of vitreous floaters.

    Material And Methods: The study included 144 patients (173 eyes) who had underwent YAG-laser vitreolysis and were under observation from 01.09. Read More

    [Prognostic factors of antiangiogenic therapy response in neovascular macular degeneration].
    Vestn Oftalmol 2018 ;134(1):48-55
    Novosibirsk State Regional Clinical Hospital, Nemirovicha-Danchenko St., 130, Novosibirsk, Russian Federation, 630008.
    The apparent success of antiangiogenic therapy in patients with neovascular age-related macular degeneration (nAMD) shows the significance of effect prognosis and continuous observation.

    Purpose: to study the influence of prognostic factors on the dynamics of functional and morphological response during anti-VEGF therapy in patients with nAMD.

    Material And Methods: Retrospective analysis of anti-angiogenic therapy results was performed on the data of 1020 patients with nAMD. Read More

    [Involutional blepharitis: modern approaches to diagnostic and treatment].
    Vestn Oftalmol 2018 ;134(1):43-47
    Research Institute of Eye Diseases, Rossolimo St., 11 A, B, Moscow, Russian Federation, 119021.
    Purpose: to identify the role of laser scanning confocal microscopy (LSCM) in diagnostic and to assess the effectiveness of involutional blepharitis treatment.

    Material And Methods: The study involved 32 patients (64 eyes) with chronic blepharitis aged in average 75.21±3. Read More

    [Clinical effectiveness study of transcranial direct current stimulation in amblyopic children].
    Vestn Oftalmol 2018 ;134(1):38-42
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, 8 bld. 2, M. Trubetskaya St., Moscow, Russian Federation, 119991.
    Purpose: to assess the neurophysiological effect and clinical effectiveness of transcranial direct current stimulation in combination with drug therapy in amblyopic children.

    Material And Methods: The study involved 32 healthy children in the age of 5-12 years and 97 patients of the same age with refractive strabismic amblyopia. All study subjects underwent standard examination including ophthalmological (visometry, refractometry in normal conditions and in cycloplegia, biomicroscopy, ophthalmoscopy, type of vision), neurophysiological methods (determination of retinal electric sensitivity threshold, electric lability of optic nerve, amplitude and latency period of visual evoked potentials, electroencephalogram wave amplitudes, localization of peak electrical activity area of the cerebral cortex), assessment of neuropsychic development and estimation of mental development coefficient with age tests. Read More

    [Vitrectomy technique in aggressive posterior retinopathy of prematurity].
    Vestn Oftalmol 2018 ;134(1):32-37
    Kaluga branch of S. Fyodorov Eye Microsurgery Federal State Institution, 5 Svyatoslava Fyodorova St., Kaluga, Russian Federation, 248007.
    Aim: to develop the methodology of early primary vitrectomy for aggressive posterior retinopathy of prematurity.

    Material And Methods: The study included 10 preterm infants (20 eyes; gestational term - 26-30 weeks, post-conceptual age - 34-39 weeks) with severe forms of aggressive posterior retinopathy of prematurity (AP-ROP). All patients underwent a complex ophthalmic examination. Read More

    [Algorithm for choosing parameters for relex smile surgery].
    Vestn Oftalmol 2018 ;134(1):24-31
    Institution of Advanced Training of Russian Federal Bio-Medical Agency, department of ophthalmology, ul. Gamalei, 15, b.4, Moscow, Russian Federation, 123098; Laser eye surgery clinic 'Sfera', ul. Starokachalovskya, 10, Moscow, Russian Federation, 117628.
    Presently ReLEx Smile as a method of vision correction in refractive surgery is becoming increasingly popular in Russia and abroad.

    Purpose: to develop an algorithm for planning the surgery and choosing its parameters, and to assess the efficacy, safety and predictability of the results in the 6-month follow-up period.

    Material And Methods: The study involved 80 patients (159 eyes) with myopia of various degrees with a mean age of 33±6 years (25 to 44 years old). Read More

    [Strength properties of rabbit cornea after femtosecond laser keratoplasty with and without different intracorneal implants].
    Vestn Oftalmol 2018 ;134(1):18-23
    Cheboksary branch of S. Fyodorov Eye Microsurgery Federal State Institution, 10 Traktorostroiteley prospekt, Cheboksary, Russian Federation, 428028.
    Aim: to conduct a comparative experimental study of the effect of the use of intracorneal implants during femtosecond laser-assisted intrastromal pocket (IP) and intrastromal tunnel (IT) formation on the strength properties of the cornea.

    Material And Methods: The experimental study was performed on 24 corneas of 12 rabbit eyes enucleated 1 month after slaughtering. All eyes were divided into 6 groups according to the method of operation. Read More

    [Electrophysiological characteristics of the retina in children with cicatrical retinopathy of prematurity].
    Vestn Oftalmol 2018 ;134(1):12-17
    Saint Petersburg State Pediatric Medical University, Litovskaya str., 2, Saint Petersburg, Russian Federation, 194100.
    Visual impairment in children with regressive retinopathy of prematurity (ROP) are diverse and widespread.

    Purpose: to describe the electrophysiological characteristics of the retina in children with I-V stages of regressive ROP.

    Material And Methods: The study included children with stages I-V aged 5 to 17 (in the disease stages of IV and V - with reattachment of the retina after surgical treatment of its detachment). Read More

    [Late complications of choroidal melanoma brachytherapy and possibility of their prevention].
    Vestn Oftalmol 2018 ;134(1):4-11
    Городская клиническая больница им. С.П. Боткина филиал No1 (офтальмологическая клиника), Мамоновский пер., 7, Москва, 123001, Российская Федерация.
    Complications and the frequency of their occurrence as the criteria of eye preservation after brachytherapy (BT) are presented in literature with inconsistencies due to the assessment being done after varied follow-up periods (1 month to 5-10 years). The evaluation of complications occurring after applying radioiodine can be found in literature. The complications after BT beta particle emitting ophthalmic applicators are seldom discussed in articles. Read More

    [Economic aspects of diabetic macular edema treatment at regional level in Russian Federation].
    Vestn Oftalmol 2017;133(6):138-148
    I.M. Sechenov First Moscow State Medical University, Malaya Trubetskaya st., 8c2, Moscow, Russian Federation, 119991; Moscow Pharmaceutical Society, Leninskaya sloboda st., 19, Moscow, Russian Federation, 115280.
    An assessment of economic burden of Diabetic Macular Edema (DME) in Russian Federation was conducted on the example of four pilot regions including Samara Region, Republic of Bashkortostan, Chuvash Republic and Yaroslavl Region. The assessment involved a newly developed interactive pharmacoeconomic model that uses data from questionnaire surveys of leading DME experts residing in the regions. In the course of the study, direct and indirect costs associated with DME were calculated. Read More

    [Idiopathic macular hole: history and status quo review].
    Vestn Oftalmol 2017;133(6):131-137
    Kazan State Medical University, Ministry of Health of the Russian Federation, Butlerov st., 49, Kazan, Republic of Tatarstan, Russian Federation, 420012.
    The article reviews the literature on one of the topical problems of vitreoretinal surgery - idiopathic macular holes. The history, concept, classification and diagnostics, as well as surgical and alternative treatment methods of macular holes are explored. Read More

    [Ahmed valve in glaucoma surgery].
    Vestn Oftalmol 2017;133(6):126-130
    Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan, 90 Pushkin St., Ufa, Russian Federation, 450008.
    This is a review on Ahmed valve application in glaucoma surgery. It contains, in particular, data on the Ahmed valve efficiency, results of experimental and histological studies of filtering bleb encapsulation, examines the use of antimetabolites and anti-VEGF agents, and discusses implantation techniques. The current appraisal of antimetabolites delivery systems integrated into the Ahmed valve is presented. Read More

    [Role of genetic markers in personalization of anti-angiogenic therapy in patients with exudative age-related macular degeneration].
    Vestn Oftalmol 2017;133(6):120-125
    Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
    The review presents data of clinical and pharmacogenetic research by Russian and foreign authors conducted within the last three years on the effectiveness of anti-angiogenic treatment against wet age-related macular degeneration (AMD). Scientific results on the association between angiogenesis-related gene polymorphisms responsible for predisposition to AMD on the one hand and a positive response to anti-VEGF therapy on the other are presented. Particular attention is paid to the main regulator of angiogenesis - the VEGF-A gene. Read More

    [Corneal collagen cross-linking in the treatment of infectious keratitis and corneal ulcers].
    Vestn Oftalmol 2017;133(6):113-119
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    In recent years, collagen cross-linking (CXL) of the cornea has acquired a new usage - in the treatment of infectious keratitis and corneal ulcers. This review was aimed at compiling the previously published data and assessing the effectiveness of the method. Read More

    [Fuchs endothelial corneal dystrophy].
    Vestn Oftalmol 2017;133(6):106-112
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Fuchs endothelial dystrophy is a severe disease characterized by slowly progressing bilateral asymmetric corneal edema usually seen in elderly patients. The primary purpose of treatment is to minimize edema-related symptoms, such as ocular discomfort and visual acuity loss. Conservative therapy is symptomatic and has a short-term positive effect that does not lead to full functional rehabilitation of the patient, while endothelial keratoplasty is pathogenetically oriented. Read More

    [Use of infrared thermography in ophthalmology].
    Vestn Oftalmol 2017;133(6):99-105
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Thermoregulation disorders are associated with Body temperature fluctuation. Both hyper- and hypothermia are evidence of an ongoing pathological process. Contralateral symmetry in the Body heat spread is considered normal, while asymmetry, if above a certain level, implies an underlying pathology. Read More

    [Rate of visual recovery after macular hole surgery with intraoperative optical coherence tomography and visualization of the internal limiting membrane].
    Vestn Oftalmol 2017;133(6):90-98
    Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslava Gasheka St., Saint-Petersburg, Russian Federation, 192283.
    Currently, multiple techniques exist to repair a macular hole, but the functional result may be largely affected by the use of dyes during surgery. With our original visualization methods, one is able to remove the internal limiting membrane (ILM) without staining, and thus to avoid the toxic effect of dyes.

    Aim: to compare anatomical and functional results of surgical closure of large macular holes with or without ILM staining. Read More

    [Specifics of visual perception in infants with familial risk of autism spectrum disorders].
    Vestn Oftalmol 2017;133(6):83-89
    Ural Federal University named after the first President of Russia B.N. Yeltsin, 19 Mira St., Ekaterinburg, Russian Federation, 620002.
    Preclinical prediction of autistic spectrum disorders (ASD) is one of the priorities of current research. Children at risk of ASD develop an atypical visual perception profile early in their lives, which influences their visual responsiveness, distribution of attention, and social orienting. In this study we have compared the oculomotor behavior in an infant at familial risk of ASD with data from two 10-month infants with typical development. Read More

    [Objective assessment of donor material for penetrating corneal transplantation].
    Vestn Oftalmol 2017;133(6):76-82
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Reliable suitability evaluation of donor material is the crucial issue of penetrating corneal transplantation. The main parameter to be considered is endothelial cell density (ECD). However, when it comes to practice, one has to admit significant variation in ECD readings of cadaver corneas obtained by different methods. Read More

    [A modified implant for upper eyelid ptosis correction in frontalis suspension surgery].
    Vestn Oftalmol 2017;133(6):69-75
    Moscow Helmholtz Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogriazskaya St., Moscow, Russian Federation, 105062.
    Aim: to develop a modified implant to correct ptosis through brow suspension and to evaluate its effectiveness.

    Material And Methods: The clinical group consisted of 20 patients (29 eyes) aged 23 to 69 years (45±5.3 years on the average) and the comparison group - of 20 patients (33 eyes) aged 19 to 77 years (47±9. Read More

    [Dynamics of electrophysiological parameters of the retina after surgical treatment of idiopathic macular hole].
    Vestn Oftalmol 2017;133(6):59-68
    Research Institute of Eye Diseases, 11 A, B Rossolimo St, Moscow, Russian Federation, 119021.
    Aim: to study the dynamics of recovery of electrophysiological parameters of the retina after surgical treatment of idiopathic macular hole (IMH) and to assess their relevance to functional prognosis of the operation.

    Material And Methods: The study included 118 patients (120 eyes) examined before and after successful IMH surgery. The patients underwent electroretinography (Ganzfeld and multifocal), static computed perimetry, and optical coherence tomography. Read More

    [Analysis of structure, causes, and risk factors of ischemic optic neuro-pathy].
    Vestn Oftalmol 2017;133(6):50-58
    Research Institute of Eye Diseases, 11 A, B Rossolimo St, Moscow, Russian Federation, 119021.
    Aim: to analyze the structure, risk factors, and causes of ischemic optic neuropathy (ION).

    Material And Methods: A total of 239 patients (303 eyes) with ION and 98 patients (185 eyes) with optic disc drusen were examined. All ION patients underwent general clinical assessment. Read More

    [Combined YAG-laser capsulotomy in pseudophakic patients with anterior capsular contraction syndrome].
    Vestn Oftalmol 2017;133(6):45-49
    Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russian Federation, 119021.
    Progressive metaplastic fibrosis of the anterior capsulorhexis opening is a frequent complication of the postoperative period. There is a widely practiced method of anterior capsular contraction syndrome (ACCS) correction through radial anterior laser capsulotomy. Despite many advantages, it can be complicated by unpredictable anterior capsule tearing and intraocular lens (IOL) dislocation into the vitreous Body, which justifies the search for new technical solutions. Read More

    [Diagnostic capabilities of optical coherence tomography and confocal laser scanning microscopy in studying manifestations of aniridia-associated keratopathy].
    Vestn Oftalmol 2017;133(6):30-44
    Research Center for Medical Genetics, 1 Moskvorech'e St., Moscow, Russian Federation, 115478; Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow, Russian Federation, 117997.
    Aim: to investigate the possible use of anterior segment optical coherence tomography (AS-OCT) and laser scanning confocal microscopy (LSCM) for visualization of limbal progenitor structures and epithelial changes at different stages of aniridia-associated keratopathy (AAK) and to analyze genotype-phenotype correlations of corneal damage.

    Material And Methods: Thirty-four patients (63 eyes) with congenital aniridia (CA) were subjected to epithelial cell density measurement in the central cornea as well as epithelial surface assessment with limbal palisades of Vogt (POV) detection in the corresponding sites of the two corneas. For that, LSCM (HRT3) and AS-OCT (RTVue XR Avanti) were performed. Read More

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