11,758 results match your criteria Annals of Ophthalmology [Journal]


[The course of delayed intrauterine infection in children with residual manifestations of retinopathy of prematurity].

Vestn Oftalmol 2020 ;136(2):143-151

N.I. Pirogov Russian National Research Medical University, Moscow, Russia.

Retinopathy of prematurity (ROP) is a severe vascular proliferative disease. The appearance of signs of intrauterine infection in the setting of ROP may aggravate the severity of the disease course and lead to development of complications. Two children with residual ROP effects were observe to have delayed manifestations of intrauterine infection. Read More

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http://dx.doi.org/10.17116/oftalma2020136021143DOI Listing
January 2020

[On the new classification of eye burns].

Vestn Oftalmol 2020 ;136(2):134-142

S.M. Kirov Military Medical Academy, St. Petersburg, Russia.

The currently used classification of eye burns was proposed in 1973 by N.A. Puchkovskaya and V. Read More

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http://dx.doi.org/10.17116/oftalma2020136021134DOI Listing
January 2020

[Long-term use of latanoprost in the treatment of glaucoma].

Authors:
N I Kurysheva

Vestn Oftalmol 2020 ;136(2):125-132

A.I. Burnazyan Federal Medical and Biophysical Center of FMBA, Moscow, Russia.

Glaucoma is the main cause of irreversible blindness in the world. Latanoprost - an ester prodrug of prostaglandin F2α (PGF2α) - was the first prostaglandin analogue used in the treatment of glaucoma. The present review shows that latanoprost is the most balanced prostaglandin analogue in terms of efficacy-safety. Read More

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http://dx.doi.org/10.17116/oftalma2020136021125DOI Listing
January 2020

[Specific biomarkers of response to antiangiogenic therapy].

Vestn Oftalmol 2020 ;136(2):117-124

S.N. Fyodorov National Medical Research Center MNTK Eye Microsurgery, Moscow, Russia.

Age-related macular degeneration (AMD) and diabetic macular edema (DME) are the main causes of blindness in the elderly and loss of central vision in patients with diabetic retinopathy, respectively. Anti-VEGF therapy is currently the gold standard for treatment of such patients; it has proved its effectiveness in both randomized clinical trials and clinical practice. However, it should be taken into account that the extent of therapeutic response varies depending on individual characteristics of patients, including the presence of biomarkers that predict the therapeutic response. Read More

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http://dx.doi.org/10.17116/oftalma2020136021117DOI Listing
January 2020

[Drug-induced glaucoma].

Vestn Oftalmol 2020 ;136(2):107-116

Russian Medical Academy of Continuous Professional Education, Moscow, Russia.

Glaucoma is seen as a heterogeneous group of diseases characterized by optical neuropathy with associated visual field loss; one of the main risk factors for its development is increased intraocular pressure (IOP). In the case of drug-induced glaucoma (DIG), patients develop elevated IOP, optic neuropathy and visual field defects associated with the use of certain drugs. Corticosteroids are one of the most well-known classes of drugs that can cause an increase in IOP through the open-angle mechanism. Read More

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http://dx.doi.org/10.17116/oftalma2020136021107DOI Listing
January 2020

[Ultraviolet crosslinking in the treatment of keratoconus in patients with thin corneas].

Vestn Oftalmol 2020 ;136(2):99-106

Eye Center Vostok-Prozrenie, Moscow, Russia.

Corneal collagen cross-linking (CXL) is a procedure that aims to halt the progression of corneal ectasia in keratoconic eyes. It is achieved by inducing cross-links in the corneal stroma and extracellular matrix by exposing it to ultraviolet-A (370 nm) irradiation while it is filled with photosensitizer (riboflavin). According to the conventional protocol, the recommended de-epithelialized corneal thickness should be higher than 400 μm in order to avoid radiation damage to the corneal endothelium. Read More

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http://dx.doi.org/10.17116/oftalma202013602199DOI Listing
January 2020

[Iris shape change and risk of anterior chamber angle closure].

Vestn Oftalmol 2020 ;136(2):93-98

Research Institute of Eye Diseases, Moscow, Russia.

Potential obstruction of the anterior chamber angle by iris root is a key factor of the pathogenesis of angle-closure glaucoma. Development and adoption of ultrasound biomicroscopy and optical coherence tomography in clinical practice have significantly expanded the capabilities of studying the structures of the anterior eye segment in terms of angle closure risk factors through improving visualization depth and quality of examination, including different variants of iris structure and potential changes of its shape in mydriasis. The article reviews various studies dedicated to the progression of primary angle-closure glaucoma and its dependence on the biometric parameters of the eye and changes in pupil size. Read More

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http://dx.doi.org/10.17116/oftalma202013602193DOI Listing
January 2020

[Treatment of chronic posterior blepharitis after allogeneic hematopoietic stem cell transplantation (a case report)].

Vestn Oftalmol 2020 ;136(2):86-92

Research Institute of Eye Diseases, Moscow, Russia.

After allogeneic hematopoietic stem cell transplantation (allo-HSCT), various eye diseases are detected in 30-60% of patients, with chronic graft-versus-host reaction - in 50-90% of patients. Among the complications, the most frequent is damage to the eye surface and eyelids. The article presents a clinical case of successful minimally invasive treatment of chronic posterior blepharitis in a patient who has undergone allogeneic hematopoietic stem cell transplantation. Read More

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http://dx.doi.org/10.17116/oftalma202013602186DOI Listing
January 2020

[The effect of the tear film on the results of a direct assessment of the sensitivity of the cornea].

Vestn Oftalmol 2020 ;136(2):81-85

Research Institute of Eye Diseases, Moscow, Russia.

Attempts to find clinical application for esthesiometry are associated with studying sensitivity disorders that occur in various diseases (diabetes mellitus, keratitis of various etiologies, corneal erosion, dry eye syndrome), as well as after surgical interventions.

Purpose: To evaluate the influence of the tear film on the results of direct assessment of corneal sensitivity.

Material And Methods: The study was conducted in a group of 20 healthy volunteers. Read More

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http://dx.doi.org/10.17116/oftalma202013602181DOI Listing
January 2020

[Effectiveness of antihypertensive conservative-free therapy with fixed combination of bimatoprost and timolol (intermediate results)].

Vestn Oftalmol 2020 ;136(2):73-80

South Ural State Medical University, Chelyabinsk, Russia.

Introduction: The effects of antihypertensive therapy are often determined by patient compliance with the prescribed treatment plan. Acceptance of conservative-free forms of drugs leads to a decrease in the frequency and severity of side effects, reduces the need for the use of artificial tears, which lowers the cost of treatment for the patients.

Purpose: to evaluate the hypotensive effectiveness of a fixed combination of bimatoprost (0. Read More

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http://dx.doi.org/10.17116/oftalma202013602173DOI Listing
January 2020

[Comparative study of factors associated with the progression of primary open-angle and angle-closure glaucoma].

Vestn Oftalmol 2020 ;136(2):64-72

Clinics of doctor ShatalovA Naberezhnaja St., Orekhovo-Zuyevo, Moscow region, Russia.

Purpose: To compare the factors associated with the progression of primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG).

Material And Methods: This prospective study analyses clinical data of POAG and PACG patients followed up for 6 years. The progression of glaucomatous optic neuropathy (GON) was determined using perimetry and spectral optical coherence tomography (OCT). Read More

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http://dx.doi.org/10.17116/oftalma202013602164DOI Listing
January 2020

[Peptide bioregulators: delivery and efficacy].

Vestn Oftalmol 2020 ;136(2):56-62

I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Purpose: To compare the neuroprotective properties of retinalamin administered in different ways among open-angle glaucoma patients with compensated intraocular pressure.

Material And Methods: The study included 498 patients (eyes) with initial, moderate and advanced stages of glaucoma. Patients were divided into 3 groups: group I (=110) received 5 mg intramuscular and 5 mg retrobulbar injections of retinalamin; group II (=171) received 5 mg retrobulbar injection of retinalamin; group III received 5 mg intramuscular injection of retinalamin. Read More

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http://dx.doi.org/10.17116/oftalma202013602156DOI Listing
January 2020

[New morphometric criteria in the study of pathogenesis of normal-tension glaucoma].

Vestn Oftalmol 2020 ;136(2):49-55

S.M. Kirov Military Medical Academy, St. Petersburg, Russia.

Introduction: Studying the factors that contribute to the disturbance of transmembrane pressure gradient is a topical task in the research of pathogenesis of normal-tension glaucoma (NTG).

Purpose: To measure and compare the thickness and depth of lamina cribrosa (LCT and LCD), as well as optic nerve subarachnoid space width (ONSASW) in patients with NTG and healthy individuals.

Material And Methods: The first group included 12 patients (23 eyes) aged from 58 to 74 years (average age 66. Read More

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http://dx.doi.org/10.17116/oftalma202013602149DOI Listing
January 2020

[Capabilities of remote laser homeostasis of the conjunctiva and sclera].

Vestn Oftalmol 2020 ;136(2):44-48

S.N. Fyodorov National Medical Research Center MNTK Eye Microsurgery, Moscow, Russia.

Introduction: During some eye surgeries, a need for hemostasis can arise in order to prevent bleeding.

Purpose: To determine the optimal settings for remote laser action of Nd:YAG laser with a wavelength of 1.44 µm on the conjunctival and episcleral vessels of the eye to stop bleeding, as well as for preemptive anemisation of tissue prior to performing a surgical incision. Read More

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http://dx.doi.org/10.17116/oftalma202013602144DOI Listing
January 2020

[Algorithm for predicting axial displacement of the optic part of IOL after phacoemulsification].

Vestn Oftalmol 2020 ;136(2):38-43

S.M. Kirov Military Medical Academy, St. Petersburg, Russia.

Purpose: To test a prediction algorithm for deflection of the optical part of IOL after uncomplicated phacoemulsification.

Material And Methods: The study included 226 patients (287 eyes) who underwent phacoemulsification with implantation of intracapsular AcrySof IOL. Preoperative examination included IOLMaster, Lenstar LS 900 biometry and Pentacam HR keratotopography. Read More

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http://dx.doi.org/10.17116/oftalma202013602138DOI Listing
January 2020

[Results of enzyme-linked immunoassay of the blood serum in patients with infectious and inflammatory diseases of the anterior segment of the eye].

Vestn Oftalmol 2020 ;136(2):32-37

S.N. Fyodorov National Medical Research Center MNTK Eye Microsurgery, Moscow, Russia.

Purpose: To evaluate the clinical significance of the data obtained during enzyme-linked immunosorbent assay (ELISA) of the blood serum of patients with inflammatory diseases of the anterior eye segment compared to a group of healthy volunteers.

Material And Methods: A retrospective analysis of the results of serum ELISA of 200 patients with chronic keratoconjunctivitis and keratouveitis was performed using the solid-phase IFA method in order to detect the presence of antibodies to herpes simplex viruses of 1 and 2 types (HSV 1, 2), cytomegalovirus (CMV), and . The control group consisted of 34 healthy volunteers with no signs of inflammation of the eye tissue. Read More

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http://dx.doi.org/10.17116/oftalma202013602132DOI Listing
January 2020

[Comparative assessment of the parameters of visual fixation in amblyopia of different origin].

Vestn Oftalmol 2020 ;136(2):26-31

Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia.

Introduction: Examination of visual fixation parameters is an important diagnostic method in patients with amblyopia of different origin.

Purpose: To study the visual fixation parameters for various types of amblyopia.

Material And Methods: The study included 108 patients (213 eyes) aged 5-11 years with moderate and high amblyopia: 27 patients (54 eyes) with strabismic amblyopia, 45 patients (87 eyes) with refractive and anisometropic amblyopia, and 36 patients (72 eyes) with relative amblyopia caused by deprivation nystagmus. Read More

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http://dx.doi.org/10.17116/oftalma202013602126DOI Listing
January 2020

[Clinical significance of aberrations of the ocular optical system in glaucoma surgery and the capabilities of minimizing them].

Vestn Oftalmol 2020 ;136(2):20-25

Dagestan Center of Eye Microsurgery, Kaspiysk, Russia.

Introduction: Despite the achievements of modern pharmacology and laser surgery, traditional glaucoma surgery remains the main method of reducing intraocular pressure (IOP). After successful glaucoma surgery, some of the patients are observed to have a decrease in visual functions not associated with progression of the glaucomatous process. This phenomenon is explained by the effect glaucoma surgery can have on eye refraction; detailed understanding of such changes would significantly speed up functional rehabilitation of these patients. Read More

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http://dx.doi.org/10.17116/oftalma202013602120DOI Listing
January 2020

[Experimental study of hyaluronic acid gel fillers biodegradation in orbit].

Vestn Oftalmol 2020 ;136(2):13-19

Research Institute of Eye Diseases, Moscow, Russia.

Introduction: Recently, hyaluronic acid gel (HAG) fillers were proposed as an effective alternative treatment option for surgical orbital volume augmentation. Several authors reported about long-standing effect of the filler.

Purpose: To assess the features of HAG biodegradation after intraorbital injection in experimental environment. Read More

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http://dx.doi.org/10.17116/oftalma202013602113DOI Listing
January 2020

[Changes in corneal nerve fibers after microinvasive cataract surgery (a preliminary report)].

Vestn Oftalmol 2020 ;136(2):6-12

I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Introduction: Potential changes in corneal nerve fibers (CNF) induced by cataract phacoemulsification remain insufficiently studied. The need for research in this direction is dictated by a number of circumstances: introduction of corneal confocal microscopy into clinical practice, the need for phaco surgery in the presence of corneal changes of various genesis, the possible negative impact of laser radiation during hybrid (femtosecond laser-assisted) phacoemulsification.

Purpose: To assess the changes in CNF after various methods of microinvasive cataract surgery. Read More

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http://dx.doi.org/10.17116/oftalma20201360216DOI Listing
January 2020

[Viral and non-viral infections in the etiopathogenesis of uveitis].

Vestn Oftalmol 2020 ;136(1):124-129

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.

The article reviews literature and proprietary data on the role of pathogens in the etiology of infectious and non-infectious uveitis. Infectious uveitis is caused by active intraocular replication of the virus (herpesvirus, acute stage of enterovirus), or by long-term persistence of the viruses in eye tissues (Fuchs syndrome associated with rubella virus, late complications of enterovirus uveitis). Clinical picture, severity, outcomes of infectious uveitis depend on the pathogen, adequacy of the immune response and genetic characteristics of the patient. Read More

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http://dx.doi.org/10.17116/oftalma2020136011124DOI Listing

[The role of the endothelin system in the pathogenesis of eye diseases].

Vestn Oftalmol 2020 ;136(1):117-123

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.

The endothelin system (ES) plays a complex role in the pathogenesis of various eye diseases as a local regulator of vascular tone as well as many other physiological processes. Components of ES - endothelins and their receptors - can be found nearly in all cellular structures of the eye, their concentration increases in the presence of many eye diseases. In glaucoma, ES is involved in the mechanisms of eye hypertension by influencing the secretion and outflow of aqueous humor. Read More

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http://dx.doi.org/10.17116/oftalma2020136011117DOI Listing

[Swept source optical coherence tomography: a technology review].

Vestn Oftalmol 2020 ;136(1):111-116

Lomonosov Moscow State University, Department of Ophthalmology, Faculty of Fundamental Medicine, 27-1 Lomonosovskiy av., Moscow, Russian Federation, 119991.

The article reviews the concept of swept source optical coherence tomography (SS-OCT) and presents a brief history of the technology, its implementation in modern commercial tomography, the advantages and disadvantages of the method. Read More

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http://dx.doi.org/10.17116/oftalma2020136011111DOI Listing

[Atomic force microscopy in the study of anterior eye segment structures].

Vestn Oftalmol 2020 ;136(1):103-110

International school 'Medicine of Future' of the Sechenov University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991.

The application of atomic force microscopy (AFM) in ophthalmology is considered with respect of the classical anatomical division of the eye into anterior and posterior segments. The review presents the findings of published research studies that involved AFM as a method for assessing anatomical and functional condition of the structures of anterior eye segment. One significant line of research is related to the use of AFM technologies for evaluation of morphological and biomechanical characteristics of various parts of the eye lens. Read More

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http://dx.doi.org/10.17116/oftalma2020136011103DOI Listing

[Treatment of chronic blepharitis].

Vestn Oftalmol 2020 ;136(1):97-102

OOONPP 'LAZMA', 8 Tvardovskogo St., Moscow, Russian Federation, 123458.

The most effective method of treating chronic blepharitis - a disease with multifactorial pathogenesis requiring an individual approach - is a combination of remedial measures that addresses eyelids hygiene and includes medicated and device therapy. Read More

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http://dx.doi.org/10.17116/oftalma202013601197DOI Listing

[Bilateral occlusion of retinal vessels in Waldenstrom's disease (a case study)].

Vestn Oftalmol 2020 ;136(1):90-96

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.

The article describes a clinical case of bilateral occlusion of retinal vessels in a patient with Waldenstrom's disease - a rare lymphoplasmocytic tumor of the bone marrow characterized by a complex of syndromes, among which the syndrome of blood hyperviscosity dominates. Comprehensive clinical, instrumental and laboratory examinations revealed that besides the syndrome of blood hyperviscosity the patient also had loci of cerebral ischemia (according to magnetic resonance imaging), ocular hypoperfusion with severe deficiency of retinal and choroidal blood flow (according to Doppler methods) indicating the presence of ocular ischemic syndrome. Since bilateral occlusion of retinal vessels without concomitant vascular and/or systemic pathology is rare, patients with such diagnosis should be referred to a hematologist. Read More

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http://dx.doi.org/10.17116/oftalma202013601190DOI Listing

[Comparative analysis of the functional results after implantation of various diffractive trifocal intraocular lenses].

Vestn Oftalmol 2020 ;136(1):80-89

A.A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, 19 Bolshoy Karetny per., bld. 1, Moscow, Russian Federation, 127051.

Purpose: To compare visual outcomes after implantation of two models of diffractive trifocal IOLs using various vision assessment systems.

Material And Methods: The study included 25 patients (25 eyes) who were implanted with AcrySof IQ PanOptix (TFN) and 25 patients (25 eyes) implanted with AT LISA tri 839 MP (TRI). Postoperative examination at 1 year included assessment of monocular visual acuity for far, intermediate and near distance using decimal scale, as well as LogMAR and an interactive computer program (ICP). Read More

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http://dx.doi.org/10.17116/oftalma202013601180DOI Listing

[The method of closing macular holes with partial preservation of the internal limiting membrane].

Vestn Oftalmol 2020 ;136(1):73-79

National Medical and Surgical Center named after N.I. Pirogov, the Ministry of Healthcare of the Russian Federation, 70 Nizhnyaya Pervomayskaya St., Moscow, Russian Federation, 105203.

Macular hole is an urgent vision impairment problem among the population of developed countries. The main method of treatment of the macular hole is vitrectomy with removal of the internal limiting membrane (ILM). However, the pilling has been recently proved to have negative impact on neurophysiological processes in the macular zone. Read More

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http://dx.doi.org/10.17116/oftalma202013601173DOI Listing

[Experimental justification of the use of a polymeric implant in reconstructive and regenerative surgery of the sclera and tarsal plate].

Vestn Oftalmol 2020 ;136(1):65-72

Kaluga branch of S.N. Fyodorov National Medical Research Center "MNTK "Eye Microsurgery", 5 Svyatoslava Fyodorova St., Kaluga, Russian Federation, 248007.

Introduction: Congenital and acquired diseases, as well as traumatic injuries of the sclera and tarsal plate can lead to serious complications up to the complete loss of visual functions and loss of the eye as an organ if not treated timely. Due to that, it becomes necessary to use biological and synthetic materials during reconstructive and regenerative surgeries to replace the defects and reinforce the carcass properties of the sclera and tarsal plate.

Purpose: To compare experimental and morphological features of the response of the eye and surrounding tissues to implantation of the synthetic polymeric implant for reconstructive and regenerative surgery (PERRS) 'Reperen-6' and biological xenopericardium implant taken from cattle on the sclera in animal experiment. Read More

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http://dx.doi.org/10.17116/oftalma202013601165DOI Listing

[Optical coherence tomography in diagnostics of small choroidal melanoma].

Vestn Oftalmol 2020 ;136(1):56-64

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.

Purpose: To determine signs of small choroidal melanoma with different pigmentation using enhanced depth imaging optical coherence tomography (EDI-OCT).

Material And Methods: The study included 344 patients with small choroidal melanoma with different pigmentation examined using EDI-OCT: 1st group - pigmented melanoma (228 eyes), 2nd group - low pigmented (65 eyes), and 3rd group - amelanotic (51 eyes).

Results: In pigmented small choroidal melanomas - elevation of choroidal profile towards vitreous, compression of choriocapillaries with a narrow even 'belt' and a 'shadow' effect; thinning, defects in Bruch's membrane; thickening of the retina above the tumor, lobulated photoreceptors; intra- and subretinal exudate (diffuse, cystic edema, neuroepithelial detachment); defects and detachment of pigment epithelium with hyperreflective foci, disorganization of the pigment with the formation of hyperreflective foci at different retinal levels. Read More

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http://dx.doi.org/10.17116/oftalma202013601156DOI Listing

[Computer technologies in diagnostics and treatment of worsening post-enucleation socket syndrome].

Vestn Oftalmol 2020 ;136(1):49-55

I.M. Sechenov First Moscow State Medical University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991.

Enucleation with primary orbital implantation and the use of ocular prosthesis does not exclude the risk of post-enucleation socket syndrome (PESS). Correction of such conditions requires modern visualization methods and software for calculation, modelling and control of the surgery.

Purpose: To demonstrate the capabilities of modern computer technologies in diagnostics and treatment of patients with worsening post-enucleation enophthalmos. Read More

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http://dx.doi.org/10.17116/oftalma202013601149DOI Listing

[Energy load and state of corneal endothelium in hybrid (femtosecond laser-assisted) and torsional phacoemulsification].

Vestn Oftalmol 2020 ;136(1):42-48

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Postoperative state of the corneal endothelium is the most important criterion for evaluating the safety of cataract phacoemulsification.

Purpose: To compare the intraoperative energy load and postoperative state of corneal endothelium in hybrid (femtosecond laser-assisted) and torsional phacoemulsification.

Material And Methods: The study analyzed surgical outcomes of 603 patients (714 eyes) divided into 3 groups: 225 patients (267 eyes) underwent modified femtosecond laser-assisted phacoemulsification (1st group), 237 patients (278 eyes) underwent standard femtosecond laser-assisted phacoemulsification (2nd group), and 141 patients (169 eyes) who underwent torsional phacoemulsification (3rd group). Read More

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http://dx.doi.org/10.17116/oftalma202013601142DOI Listing

[Signs of proliferative process after laser treatment of advanced glaucoma].

Vestn Oftalmol 2020 ;136(1):36-41

S.N. Fyodorov National Medical Research Center "MNTK "Eye Microsurgery", 59A Beskudnikovsky Blvd., Moscow, Russian Federation, 127486.

The universally established method for effective and less-invasive reduction of the intraocular pressure (IOP) in patients with primary open-angle glaucoma (POAG) is a two-step method consisting of non-penetrating deep sclerectomy (NDSE) followed by laser goniopuncture of the Descemet's membrane (Descemet's goniopuncture; DGP). However, the hypotensive effect can diminish at different times during the follow-up due to excessive scarring in surgically formed outflow tracts (SFOT).

Purpose: To evaluate the condition of SFOT in dynamics with Visante OCT after one-step combined laser technique consisting of modified selective laser activation of the trabecula (MSLAT) and DGP in advanced POAG patients with normalized IOP who have pronounced pigmentation of the trabecular meshwork and stage II pseudoexfoliation syndrome (PES). Read More

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http://dx.doi.org/10.17116/oftalma202013601136DOI Listing

[Spatial contrast sensitivity in patients with primary open-angle glaucoma and ocular hypertension].

Vestn Oftalmol 2020 ;136(1):25-35

Chelyabinsk Regional Clinical Hospital No. 3, 287 Pobedy av., Chelyabinsk, Russian Federation, 454021.

Up to now, there has not been a comparison of spatial contrast sensitivity (SCS) in patients with primary and pseudoexfoliation open-angle glaucoma (POAG; PEG) and ophthalmic hypertension (OH).

Purpose: To study the characteristics of SCS in patients with POAG, PEG (as well as in the paired eye without glaucoma) and OH.

Material And Methods: The work was performed in the period from 2011 to July 2017. Read More

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http://dx.doi.org/10.17116/oftalma202013601125DOI Listing

[Biomechanical properties of the cornea as predictors of the effectiveness of selective laser trabeculoplasty].

Vestn Oftalmol 2020 ;136(1):17-24

Ophthalmological Center of the Federal Medical-Biological Agency of the Russian Federation, A.I. Burnazyan Federal Medical and Biophysical Center of FMBA, 15 Gamalei St., Moscow, Russian Federation, 123098.

Purpose: To study the changes in central corneal thickness (CCT) and corneal hysteresis (CH) after selective laser trabeculoplasty (SLT) in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) after laser peripheral iridotomy (LPI) and to determine their effect on the prognosis of the surgery.

Material And Methods: The prospective study involved 68 eyes with initial PACG after LPI and 74 eyes with initial POAG observed for 6 months. Corneal-compensated IOP (IOPcc), corneal resistance factor (CRF), CH and CCT were studied as the predictors of SLT, which was considered successful when IOPcc decreased by 20% or more from the baseline without additional hypotensive therapy and/or repeated SLT. Read More

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http://dx.doi.org/10.17116/oftalma202013601117DOI Listing

[Morphological and functional condition of the macula after different types of phaco cataract surgeries].

Vestn Oftalmol 2020 ;136(1):4-16

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, Department of Ophthalmology, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991.

One of the directions of advancing phaco technology is related to adoption of hybrid phacoemulsification for clinical practice. Potential postsurgical changes in the macular area, when other factors are equal, can be seen as a conditional criterion for the injury rate of phaco surgeries.

Purpose: To evaluate morphological and functional condition of the macular area after different types of phaco cataract surgeries. Read More

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http://dx.doi.org/10.17116/oftalma20201360114DOI Listing

[Visual acuity assessment: historical overview and current trends].

Vestn Oftalmol 2019 ;135(6):141-146

Lomonosov Moscow State University, Faculty of Fundamental Medicine, 27/1 Lomonosov Av., Moscow, Russian Federation, 119991.

The article reviews the evolution of visual acuity assessment and gives comparison of the visual acuity charts (Snellen vs. ETDRS) widely used in research and clinical practice. Read More

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http://dx.doi.org/10.17116/oftalma2019135061141DOI Listing
February 2020

[A differentiated approach to analysis of retinal fluid and assessment of its effect on anti-VEGF therapy of neovascular age-related macular degeneration].

Authors:
T G Kamenskih

Vestn Oftalmol 2019 ;135(6):134-140

Saratov State Medical University named after V.I. Razumovsky, 112 Bolshaya Kazachia St., Saratov, Russian Federation, 410012.

Neovascular age-related macular degeneration (nAMD) causes rapid irreversible vision loss presenting a serious socio-economic problem. The recommended approach to the treatment of this pathology is the use of angiogenesis inhibitors (anti-VEGF drugs). Following the proactive principles when conducting anti-VEGF treatment helps achieve the maximum therapeutic efficacy. Read More

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http://dx.doi.org/10.17116/oftalma2019135061134DOI Listing
February 2020

[The role of infection foci in the onset and sustenance of inflammatory diseases of the eye].

Vestn Oftalmol 2019 ;135(6):124-133

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Numerous clinical observations indicate the importance of the role of 'focal sepsis' in the development and facilitation of inflammation in the anterior eye segment. The article describes possible routes of infection spread from various local foci to the eye. Studying the connection between local infection foci and inflammatory eye diseases will give ophthalmologists more opportunities for effective treatment and prevention of disease recurrences. Read More

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http://dx.doi.org/10.17116/oftalma2019135061124DOI Listing
February 2020

[Continuous anti-glaucoma drug therapy as a risk factor of dry eye].

Vestn Oftalmol 2019 ;135(6):117-123

Yerevan State Medical University after Mkhitar Heratsi, 2 Koryuna St., Erevan, Republic of Armenia, 0025.

A preservative is a mandatory component of the eye drops designed to prevent microbial contamination in an opened bottle. Most of the preservative agents are either detergents, or oxidants; the most widely used and well-studied preservative - benzalkonium chloride - is a detergent. Due to regular usage of glaucoma eye drops, cytotoxic impact of the preservatives on anterior eye surface is considered the principal cause of its pathology, which leads to a decrease in quality of life. Read More

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http://dx.doi.org/10.17116/oftalma2019135061117DOI Listing
February 2020

[Diffuse choroidal hemangioma as a manifestation of Sturge-Weber syndrome (a clinical case study)].

Vestn Oftalmol 2019 ;135(6):108-116

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Encephalotrigeminal angiomatosis (Sturge-Weber syndrome) is a congenital sporadic disease characterized by angiomatosis of meningeal vessels, facial and eye capillaries. The article presents a clinical case of comorbidity between monolateral skin angioma, ipsilateral conjunctival and choroidal angiomas without intraocular pressure elevation. The case is unusual due to asynchronous manifestation of the clinical signs of Sturge-Weber syndrome. Read More

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http://dx.doi.org/10.17116/oftalma2019135061108DOI Listing
February 2020

[Papillomacular retinoschisis associated with glaucoma].

Vestn Oftalmol 2019 ;135(6):100-107

Volga District Medical Centre, Federal Medical and Biological Agency, 2 Nizhnevolgskaya Naberejnaya, Nizhny Novgorod, Russian Federation, 603001.

Peripapillary and macular retinoschisis is one of the rare manifestations of advanced glaucoma of different types. The article presents a case report and a mini-review. Peripapillary and macular retinoschisis with visual deterioration was diagnosed in a patient with advanced decompensated open-angle glaucoma and pseudoexfoliation syndrome. Read More

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http://dx.doi.org/10.17116/oftalma2019135061100DOI Listing
February 2020

[Ophthalmologic manifestations of Waardenburg syndrome].

Vestn Oftalmol 2019 ;135(6):91-99

Ophthalmological Diagnostic Center no. 7 for children and adults, 38 Mohovaya St., Saint Petersburg, Russian Federation, 191028.

The Waardenburg syndrome is a group of rare genetic diseases, which clinical manifestations include neurosensory hearing loss, diminished pigmentation of forelock in the frontal region, iris heterochromia, medial canthus dystopia, and the presence of such changes in first-line relatives. The article presents a clinical case of type I Waardenburg syndrome, which developed de novo in a family. This case is unique in its combination of complete bilateral iris heterochromia and impaired choroidal pigmentation. Read More

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http://dx.doi.org/10.17116/oftalma201913506191DOI Listing
February 2020

[Causes, prevention and correction of refractive errors after phacoemulsification with intraocular lens implantation].

Vestn Oftalmol 2019 ;135(6):83-90

'K+31' Clinic, 42/4 Lobachevskogo St., Moscow, Russian Federation, 119415.

Purpose: To evaluate the influence of dry eye disease (DED) in cataract patients on refractive results of phacoemulsification with implantation of intraocular lenses (IOLs).

Material And Methods: The study included 24 patients (24 eyes) with early cataract or phacosclerosis who planned to undergo phacoemulsification with implantation of multifocal IOL. Inclusion criteria was preoperative presence of DED. Read More

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http://dx.doi.org/10.17116/oftalma201913506183DOI Listing
February 2020

[Effectiveness of a nonsteroidal anti-inflammatory drug in the treatment of chronic non-infectious blepharitis].

Vestn Oftalmol 2019 ;135(6):73-82

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Anti-inflammatory therapy is a type of etiopathogenetic treatment of chronic mixed blepharitis. Nonsteroidal anti-inflammatory drugs (NSAIDs) have pronounced anti-inflammatory effect comparable to the action of corticosteroids.

Purpose: To assess of the effectiveness of a NSAID - 0. Read More

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http://dx.doi.org/10.17116/oftalma201913506173DOI Listing
February 2020

[Combination therapy in patients with concomitant macular edema and proliferative diabetic retinopathy].

Vestn Oftalmol 2019 ;135(6):67-72

Moscow Regional Research and Clinical Institute, 61/2-11 Shchepkina St., Moscow, Russian Federation, 129110.

Diabetic macular edema (DME) is a serious complication of diabetic retinopathy. Numerous multicenter studies of the effectiveness of various treatment methods for DME do not give unambiguous recommendations for the treatment of refractory DME, and combinations of various forms of therapy continue to be actively studied.

Purpose: To study the effectiveness of the combination of intravitreal administration of the drug Ozurdex with subsequent individually selected laser therapy in the treatment of the proliferative stage of diabetic retinopathy in patients with concomitant chronic DME, and its relationship with morphological changes in the retina observed with optical coherence tomography. Read More

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http://dx.doi.org/10.17116/oftalma201913506167DOI Listing
February 2020

[Clinical and theoretical substantiation of geometrical, optical and functional features of the pupil of the artificial iris].

Vestn Oftalmol 2019 ;135(6):60-66

S.N. Fyodorov National Medical Research Center 'MNTK 'Eye Microsurgery', 59A Beskudnikovsky Blvd., Moscow, Russian Federation, 127486.

Presence of an extensive iris defect requires implantation of artificial iris (AI) to close it. With biometric parameters of the AI being as close to an intact eye as possible, it becomes viable to achieve good clinical and functional results with the surgery.

Purpose: To validate the optimal biometric parameters of the pupil of artificial iris using methods of clinical and theoretical analysis. Read More

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http://dx.doi.org/10.17116/oftalma201913506160DOI Listing
February 2020

[The effect of preservative-free treatment of primary open-angle glaucoma on the state of ocular surface in combination therapy (intermediate results)].

Vestn Oftalmol 2019 ;135(6):52-59

South Ural State Medical University, 64 Vorovskogo St., Chelyabinsk, Russian Federation, 454092.

The goal of antihypertensive therapy is to reduce intraocular pressure (IOP). Sometimes it can only be achieved by using two or more drugs, which can lead to undesirable side effects on the ocular surface. The use of drugs that do not contain preservatives leads to fewer undesirable side effects, while also reducing the need for instillations of artificial tears, making it economically beneficial for patients. Read More

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http://dx.doi.org/10.17116/oftalma201913506152DOI Listing
February 2020

[Influence of treatment adherence on the progression of primary open-angle glaucoma in clinical setting].

Vestn Oftalmol 2019 ;135(6):42-51

Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky, 158 Novo-Sadovaya St., Samara, Russian Federation, 443068.

According to various studies, treatment adherence of patients with primary open-angle glaucoma ranges from 5% to 80% and significantly influences the effectiveness of the therapy. Some authors report higher levels of adherence in patients receiving preservative-free medications.

Purpose: To study the influence of treatment adherence in patients receiving preservative-free and preserved medications on the progression of primary open-angle glaucoma (POAG). Read More

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http://dx.doi.org/10.17116/oftalma201913506142DOI Listing
February 2020

[Nitrogen and oxygen levels in placenta - a predictor for retinopathy of prematurity].

Vestn Oftalmol 2019 ;135(6):33-41

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021.

Purpose: To study the distribution of chemical elements in the placenta of pregnant women at 24-35 and 39-40 weeks of gestation, and to assess the possibility of using data on the levels of principle chemicals for predicting clinical manifestation of retinopathy of prematurity (ROP).

Material And Methods: The study examined 375 placenta tissue fragments of pregnant women for levels of the following chemical elements: carbon (C), nitrogen (N), oxygen (O), calcium (Ca), chlorine (Cl), potassium (K), sodium (Na) and phosphorus (P). Subjects were divided into 3 groups: 1st group consisted of 41 pregnant females (205 fragments of placenta tissue) at weeks 24-35 of gestation, whose children would not develop ROP; 2nd group included 14 mothers (70 fragments of placenta tissue) at weeks 39-40 of gestation; 3rd group - 20 pregnant (100 fragments of placenta tissue) at weeks 24-35 of gestation, whose children would be diagnosed with ROP. Read More

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http://dx.doi.org/10.17116/oftalma201913506133DOI Listing
February 2020