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    2276 results match your criteria Annals of Nutrition and Metabolism[Journal]

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    Estimating Usual Intake in the 2nd Bavarian Food Consumption Survey: Comparison of the Results Derived by the National Cancer Institute Method and a Basic Individual Means Approach.
    Ann Nutr Metab 2017 Sep 21;71(3-4):164-174. Epub 2017 Sep 21.
    Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
    Background: The valid estimation of the usual dietary intake remains a challenge till date. We applied the method suggested by the National Cancer Institute (NCI) to data from the 2nd Bavarian Food Consumption Survey (BVS II) and compared it to an individual means approach.

    Methods: Within the cross-sectional BVS II, 1,050 Bavarian residents aged 13-80 years participated in a personal interview and completed three 24-h dietary recalls by telephone interview. Read More

    Savoring Sweet: Sugars in Infant and Toddler Feeding.
    Ann Nutr Metab 2017 14;70 Suppl 3:38-46. Epub 2017 Sep 14.
    The Ohio State University School of Medicine, Columbus, OH, USA.
    During the first years of life, the sweetness of sugars has a capacity to hinder or to help in laying a strong nutritional foundation for food preferences that often extend over a lifetime. Aside from supplying 4 g/kcal of energy, sugars are non-nutritive. However, sugars have a powerful attribute, sweetness, which strongly influences human food preference. Read More

    Type 1 Taste Receptors in Taste and Metabolism.
    Ann Nutr Metab 2017 14;70 Suppl 3:27-36. Epub 2017 Sep 14.
    Rutgers University Department of Nutritional Sciences, New Brunswick, NJ, USA.
    Our sense of taste allows us to evaluate the nutritive value of foods prior to ingesting them. Sweet taste signals the presence of sugars, and savory taste signals the presence of amino acids. The ability to identify these macronutrients in foods was likely crucial for the survival of our species when nourishing food sources were sparse. Read More

    Flavor Perception and Preference Development in Human Infants.
    Ann Nutr Metab 2017 14;70 Suppl 3:17-25. Epub 2017 Sep 14.
    The College of William & Mary, Williamsburg, VA, USA.
    As most parents and caregivers are aware, feeding children a nutritionally balanced diet can be challenging. Children are born with a biological predisposition to prefer sweet and to avoid bitter foods such as green leafy vegetables. It has been hypothesized that this predisposition evolved to attract children to energy-dense foods while discouraging the consumption of toxins. Read More

    Does Breastfeeding Shape Food Preferences? Links to Obesity.
    Ann Nutr Metab 2017 14;70 Suppl 3:8-15. Epub 2017 Sep 14.
    Department of Kinesiology, California Polytechnic State University, San Luis Obispo, CA, USA.
    The first 2 years of life have been recognized as a critical window for obesity prevention efforts. This period is characterized by rapid growth and development and, in a relatively short period of time, a child transitions from a purely milk-based diet to a more varied solid-food diet. Much learning about food and eating occurs during this critical window, and it is well-documented that early feeding and dietary exposures predict later food preferences, eating behaviors, and dietary patterns. Read More

    Reduced Serum Phosphorus Levels Were Associated with Metabolic Syndrome in Men But Not in Women: A Cross-Sectional Study among the Japanese Population.
    Ann Nutr Metab 2017 Sep 8;71(3-4):150-156. Epub 2017 Sep 8.
    Department of Internal Medicine, Iida Municipal Hospital, Nagano, Japan.
    Background: Reduced serum phosphorus (SP) levels are reported to be associated with insulin resistance and metabolic syndrome (MetS). However, there have been a few gender-specific studies although SP levels are substantially different between men and women.

    Methods: This is a cross-sectional study. Read More

    Benefits of Curcumin Supplementation on Antioxidant Status in β-Thalassemia Major Patients: A Double-Blind Randomized Controlled Clinical Trial.
    Ann Nutr Metab 2017 Sep 8;71(3-4):136-144. Epub 2017 Sep 8.
    National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: β-Thalassemia major, the most common inherited anemia in the world, is associated with imbalance in the oxidant-antioxidant system. The objective of this study was to evaluate the efficacy of curcumin supplementation on markers of oxidative stress in patients with β-Thalassemia.

    Methods: This double-blind randomized controlled clinical trial was performed on 61 β-thalassemia major patients. Read More

    Clinical Significance of Area of Psoas Major Muscle on Computed Tomography after Gastrectomy in Gastric Cancer Patients.
    Ann Nutr Metab 2017 Sep 8;71(3-4):145-149. Epub 2017 Sep 8.
    Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
    Background: The measurement of a single abdominal image on computed tomography (CT) can provide an estimate of the total body skeletal muscle. We evaluate the change of the area of the psoas major muscle (PMMA) in a CT which was performed routinely after gastrectomy in gastric cancer.

    Methods: A total of 119 gastric cancer patients who underwent gastrectomy were enrolled for the study. Read More

    Simple Age Specific Cutoff Value for Sarcopenia Evaluated by Computed Tomography.
    Ann Nutr Metab 2017 Sep 8;71(3-4):157-163. Epub 2017 Sep 8.
    Department of Emergency Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
    Objective: Until now, cutoff values of low skeletal muscle mass using computed tomography (CT) were driven by optimal stratification to predict mortality in cancer patients. The aim of the present study was to investigate the simple, age-specific, cutoff value of low skeletal muscle mass by CT in healthy adults.

    Design: This is a retrospective, observational, single-center study. Read More

    Effects of Inadequate Amino Acid Mixture Intake on Nutrient Supply of Adult Patients with Phenylketonuria.
    Ann Nutr Metab 2017 Aug 26;71(3-4):129-135. Epub 2017 Aug 26.
    Division of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital Zurich, Zurich, Switzerland.
    Background: Adult phenylketonuria (PKU) patients often reduce their intake of amino acid mixture (AAM) to less than the prescribed amounts. Effects of reduced AAM intake on nutrient supply were evaluated.

    Methods: Nutrient intake was calculated in 20 adult PKU patients based on a structured food record and complemented by laboratory assessment of nutritional status. Read More

    Revised Reference Values for Potassium Intake.
    Ann Nutr Metab 2017 11;71(1-2):118-124. Epub 2017 Aug 11.
    German Nutrition Society, Bonn, Germany.
    Background: The nutrition societies of Germany, Austria and Switzerland have revised the reference values for potassium intake in January 2017.

    Methods: For adults, the estimated value was based on the 24-h urinary potassium excretion and on preventive considerations regarding hypertension and stroke. The estimated values for children and adolescents were extrapolated from the adult estimated value considering differences in body mass. Read More

    Paediatric Home Parenteral Nutrition in the Czech Republic and Its Development: Multicentre Retrospective Study 1995-2011.
    Ann Nutr Metab 2017 29;71(1-2):99-106. Epub 2017 Jul 29.
    Department of Paediatric Surgery, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, In Memoriam, Prague, Czech Republic.
    Background: Treatment quality and outcomes of paediatric home parenteral nutrition (HPN) program during its development in the Czech Republic.

    Methods: A retrospective study of patients receiving HPN from May 1995 till June 2011.

    Results: Sixty-six patients were treated in 8 centres. Read More

    Clinical Outcomes of Dietary Replacement of Saturated Fatty Acids with Unsaturated Fat Sources in Adults with Overweight and Obesity: A Systematic Review and Meta-Analysis of Randomized Control Trials.
    Ann Nutr Metab 2017 29;71(1-2):107-117. Epub 2017 Jul 29.
    Division of Nutritional Sciences, Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
    Background: Obesity and dyslipidemia are frequently treated with dietary interventions before pharmacotherapy is given. Diets high in unsaturated fat have proven advantageous to disease treatment.

    Aims: The purpose of this systematic review and meta-analysis was to assess the evidence of the effect of saturated fatty acids (SFA) replacement with unsaturated fatty acids (UFA) in metabolically healthy adults with overweight and obesity on markers of dyslipidemia and body composition. Read More

    Serum Phospholipid Fatty Acid Composition in Cystic Fibrosis Patients with and without Liver Cirrhosis.
    Ann Nutr Metab 2017 22;71(1-2):91-98. Epub 2017 Jul 22.
    Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, Poland.
    Background/aims: Cystic fibrosis (CF) liver disease is the third most frequent cause of death in CF patients. Although it alters fatty acid (FA) metabolism, data concerning the profile of FA in CF patients with liver cirrhosis is lacking. This study aimed to assess the FA composition of serum phospholipids in CF patients with and without liver cirrhosis. Read More

    β-Carotene Concentration and Its Association with Inflammatory Biomarkers in Spanish Schoolchildren.
    Ann Nutr Metab 2017 14;71(1-2):80-87. Epub 2017 Jul 14.
    Sección Departamental de Química Analítica, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.
    Aim: To examine the correlation between inflammatory biomarkers and plasma β-carotene levels in children.

    Methods: A total of 564 Spanish schoolchildren aged 9-12 were observed and studied. Plasma β-carotene levels were assessed by HPLC. Read More

    Long-Term Health Impact of Early Nutrition: The Power of Programming.
    Ann Nutr Metab 2017 6;70(3):161-169. Epub 2017 Jul 6.
    Division of Metabolic and Nutritional Medicine, Ludwig-Maximilians-Universität Munich, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.
    The Power of Programming conference 2016 at Ludwig-Maximilians-Universität Munich brought together about 600 researchers and other stakeholders from around the world who reviewed the recent evidence on the lasting health impact of environment and nutrition during early life, from pre-pregnancy to early childhood. The conference was hosted by the Early Nutrition Project, a multidisciplinary research collaboration funded by the European Commission with collaborating researchers from 35 institutions in 15 countries in Europe, the United States and Australia. The project explores the early origins of obesity, adiposity and associated non-communicable diseases, underlying mechanisms and opportunities for prevention. Read More

    Low Oxygen Consumption is Related to a Hypomethylation and an Increased Secretion of IL-6 in Obese Subjects with Sleep Apnea-Hypopnea Syndrome.
    Ann Nutr Metab 2017 4;71(1-2):16-25. Epub 2017 Jul 4.
    University of Navarra, Department of Nutrition, Food Science and Physiology, School of Pharmacy and Nutrition, Pamplona, Spain.
    Background: Deoxyribonucleic acid (DNA) methylation is an epigenetic modification involved in gene expression regulation, usually via gene silencing, which contributes to the risks of many multifactorial diseases. The aim of the present study was to analyze the influence of resting oxygen consumption on global and gene DNA methylation as well as protein secretion of inflammatory markers in blood cells from obese subjects with sleep apnea-hypopnea syndrome (SAHS).

    Methods: A total of 44 obese participants with SAHS were categorized in 2 groups according to their resting oxygen consumption. Read More

    International Society for the Study of Fatty Acids and Lipids 2016 Debate: For Science-Based Dietary Guidelines on Fats, Meta-Analysis and Systematic Reviews Are Decisive.
    Ann Nutr Metab 2017 4;71(1-2):26-30. Epub 2017 Jul 4.
    ScienceVoice Consulting, Denver, CO, USA.
    This paper summarizes a debate on whether meta-analyses and systematic reviews are decisive in formulating guidelines for dietary fat. Held during the 12th congress of the International Society for the Study of Fatty Acids and Lipids in Stellenbosch, South Africa, September 7, 2016, the debate was hosted by the International Union of Nutritional Sciences and the International Expert Movement to Improve Dietary Fat Quality (IEM, www.theiem. Read More

    Predictive Accuracy of Calf Circumference Measurements to Detect Decreased Skeletal Muscle Mass and European Society for Clinical Nutrition and Metabolism-Defined Malnutrition in Hospitalized Older Patients.
    Ann Nutr Metab 2017 24;71(1-2):10-15. Epub 2017 Jun 24.
    Department of Nutrition and Dysphagia Rehabilitation, Tamana Regional Health Medical Center, Kumamoto, Japan.
    Background/aims: The ability to readily diagnose sarcopenia and malnutrition in a clinical setting is essential. This study is aimed at clarifying the calf circumference (CC) cut-off values for decreased skeletal muscle mass (SMM), according to the Asian Work Group for Sarcopenia's criteria definition of sarcopenia, and those for European Society for Clinical Nutrition and Metabolism-defined malnutrition, in hospitalized Japanese patients.

    Methods: The study involved 1,164 patients aged ≥65 years. Read More

    Association between Thyroid Function and Body Mass Index: A 10-Year Follow-Up.
    Ann Nutr Metab 2017 16;70(4):338-345. Epub 2017 Jun 16.
    Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background/aims: We aimed to evaluate the association between change in thyroid function tests within the euthyroid range and body mass index (BMI) in persons with normal weight at baseline.

    Methods: This study investigated 1,100 normal-weight euthyroid persons in a population-based cohort study, Tehran Thyroid Study. BMI was calculated and serum concentrations of thyrotropin (TSH) and free T4 (FT4) were assayed at baseline and after 10 years of follow-up. Read More

    Prevalence of Hyponatremia and Its Associated Morbimortality in Hospitalized Patients Receiving Parenteral Nutrition.
    Ann Nutr Metab 2017 16;71(1-2):1-7. Epub 2017 Jun 16.
    Endocrinology and Nutrition Department, Hospital Clínico Universitario de Valladolid-IEN, Facultad de Medicina Universidad de Valladolid, Valladolid, Spain.
    Background: The objective of the study was to determine the prevalence of hyponatremia (HN) and its associated morbimortality in hospitalized patients receiving parenteral nutrition (PN).

    Methods: A retrospective study including 222 patients receiving total PN (parenteral nutrition group [PNG]) over a 7-month period in a tertiary hospital and 176 matched to 179 control subjects without PN (control subjects group [CSG]). Demographic data, Charlson Comorbidity Index (CCI), date of HN detection-(serum sodium or SNa <135 mmol/L)-intrahospital mortality, and hospital length-of-stay (LOS) were registered. Read More

    Relationship between Sodium Intake and Water Intake: The False and the True.
    Ann Nutr Metab 2017 15;70 Suppl 1:51-61. Epub 2017 Jun 15.
    INSERM Unit 1138, Centre de Recherche des Cordeliers, Paris, France.
    Background: Generally, eating salty food items increases thirst. Thirst is also stimulated by the experimental infusion of hypertonic saline. But, in steady state, does the kidney need a higher amount of water to excrete sodium on a high than on a low sodium intake? This issue is still controversial. Read More

    Under What Conditions do Water-Intervention Studies Significantly Improve Child Body Weight?
    Ann Nutr Metab 2017 15;70 Suppl 1:62-67. Epub 2017 Jun 15.
    Children's Hospital Oakland Research Institute, Oakland, CA, USA.
    There are particular conditions that may optimize the effects of drinking-water interventions on body weight change and risk of obesity. Strategic planning to create and sustain conditions for optimal effects of drinking water may maximize the impact of school-based interventions to reduce childhood obesity. This paper proposes questions about the target population, type of diet and activity level that will be maintained during the intervention, and planned intervention message(s). Read More

    Shifting Focus: From Hydration for Performance to Hydration for Health.
    Ann Nutr Metab 2017 15;70 Suppl 1:4-12. Epub 2017 Jun 15.
    Danone Research, Hydration and Health Department, Palaiseau, France.
    Over the past 10 years, literature on hydration biomarkers has evolved considerably - from (de)hydration assessment towards a more global definition of biomarkers of hydration in daily life. This shift in thinking about hydration markers was largely driven by investigating the differences that existed between otherwise healthy individuals whose habitual, ad-libitum drinking habits differ, and by identifying physiological changes in low-volume drinkers who subsequently increase their water intake. Aside from obvious differences in urinary volume and concentration, a growing body of evidence is emerging that links differences in fluid intake with small, but biologically significant, differences in vasopressin (copeptin), glomerular filtration rate, and markers of metabolic dysfunction or disease. Read More

    Polycystic Kidney Disease and the Vasopressin Pathway.
    Ann Nutr Metab 2017 15;70 Suppl 1:43-50. Epub 2017 Jun 15.
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
    Vasopressin, also known as arginine vasopressin or antidiuretic hormone, plays a pivotal role in maintaining body homeostasis. Increased vasopressin concentrations, measured by its surrogate copeptin, have been associated with disease severity as well as disease progression in polycystic kidney disease (PKD), and in experimental studies vasopressin has been shown to directly regulate cyst growth. Blocking vasopressin effects on the kidney via the vasopressin V2-receptor and lower circulating vasopressin concentration are potential treatment opportunities that have been the subject of study in PKD in recent years. Read More

    The Discovery of Water Channels (Aquaporins).
    Ann Nutr Metab 2017 15;70 Suppl 1:37-42. Epub 2017 Jun 15.
    Center for Systems Biology and Program in Membrane Biology/Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
    The movement of water into and out of cells is a fundamental biological process that is essential for life. Such water movement not only regulates the activity of individual cells but also is responsible for the functioning of many organ systems and for maintaining whole body water balance. It had long been suspected that water movement across biological cell membranes was in some way enhanced or facilitated by pores or channels, but the search to identify these channels was long and tedious. Read More

    Effects of Dehydration on Brain Functioning: A Life-Span Perspective.
    Ann Nutr Metab 2017 15;70 Suppl 1:30-36. Epub 2017 Jun 15.
    F. Hoffmann-La Roche Ltd., Basel, Switzerland.
    Background: In the last 10 years, there has been an increase in the publication of literature dealing with the effects of mild dehydration on cognition in healthy adults. Fewer studies, leading to less consistent data, involved other age groups.

    Summary: In healthy young adults refraining from drinking or participating in dehydration protocols, it was found that mild dehydration had no impact on performance, whereas the mood was widely impaired. Read More

    Assessing a Tool for Self-Monitoring Hydration Using Urine Color in Pregnant and Breastfeeding Women: A Cross-Sectional, Online Survey.
    Ann Nutr Metab 2017 15;70 Suppl 1:23-29. Epub 2017 Jun 15.
    Danone Research, Palaiseau, France.
    Background: Pregnant and breastfeeding women experience great changes in their total body water content and water dynamics. To support the accretion of total body water during pregnancy and compensate for the water lost through breast milk during breastfeeding, increased adequate intakes (AI) for total water have been established by various health authorities. Despite this widespread advice, several studies suggest that pregnant and breastfeeding women do not meet the AI for total water, suggesting the need to raise women's awareness on the importance of adequate water intake, particularly during pregnancy and breastfeeding, as well as to provide them with a simple means of monitoring their hydration on a day-to-day basis. Read More

    Monitoring Body Water Balance in Pregnant and Nursing Women: The Validity of Urine Color.
    Ann Nutr Metab 2017 15;70 Suppl 1:18-22. Epub 2017 Jun 15.
    Department of Kinesiology, Human Performance Laboratory, University of Connecticut, Storrs, CT, USA.
    Background: Urine osmolality (UOSM) reflects the renal regulation of excess fluid or deficit fluid, and therefore, serves as a marker of hydration status. Little is known about monitoring hydration in pregnant and lactating women despite significant physiological challenges to body water balance during that time. Therefore, we designed a study to assess if urine color (UCOL), an inexpensive and practical method, was a valid means of assessing urine concentration. Read More

    Pregnant and Breastfeeding Women: Drinking for Two?
    Ann Nutr Metab 2017 15;70 Suppl 1:13-17. Epub 2017 Jun 15.
    Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
    The primary aim of this cross-sectional survey was to assess the total fluid intake (TFI; sum of drinking water and all other fluids) and the intake of water and all other types of beverages in a sample of pregnant and breastfeeding women representative of Java-Island, Indonesia. Therefore, 299 pregnant and 296 breastfeeding women completed a 7-day fluid-specific record. A secondary aim was to estimate the total water intake (TWI; sum of water from fluids and food moisture), and one 24-h recall was performed to determine water intake from food moisture. Read More

    Relationship between Changes in Fatty Acid Composition of the Erythrocyte Membranes and Fatty Acid Intake during Pregnancy in Pregnant Japanese Women.
    Ann Nutr Metab 2017 9;70(4):268-276. Epub 2017 Jun 9.
    Wellness and Nutrition Science Institute, Morinaga Milk Industry, Co., Ltd., Kanagawa, Japan.
    Objective: Docosahexaenoic acid (DHA) is an important nutrient required by pregnant women and fetuses. Several studies suggest that fatty acid composition changes during pregnancy. However, the association of longitudinal changes in erythrocyte fatty acid composition and dietary fatty acid intake during pregnancy is not well understood. Read More

    Increased Incretin But Not Insulin Response after Oral versus Intravenous Branched Chain Amino Acids.
    Ann Nutr Metab 2017 9;70(4):293-302. Epub 2017 Jun 9.
    Centre for Research on Diabetes, Metabolism and Nutrition of Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
    Background/aims: Branched chain amino acids (BCAAs) are known to exert an insulinotropic effect. Whether this effect is mediated by incretins (glucagon like peptide 1 [GLP-1] or glucose-dependent insulinotropic peptide [GIP]) is not known. The aim of this study was to show whether an equivalent dose of BCAA elicits a greater insulin and incretin response when administered orally than intravenously (IV). Read More

    Physical Growth and Biological Maturation of Children and Adolescents: Proposed Reference Curves.
    Ann Nutr Metab 2017 9;70(4):329-337. Epub 2017 Jun 9.
    Faculdade de Educação Física, Universidade Municipal de São Caetano do Sul (USCS), São Paulo, Brazil.
    Background/aim: The study of physical growth variables in terms of chronological age and biological maturation may provide a common reference point to reflect on the occurrence of body dimensions in and between individuals. The objectives of this study were as follows: (a) verify if the observed gender differences in the variables of physical growth by chronological age are confounded by physical maturation, (b) compare physical growth patterns with the reference of the Centers for Disease Control and Prevention (CDC)-2012, and (c) develop regional curves to assess physical growth in terms of biological maturation.

    Methods: Researchers studied 3,674 children and adolescents. Read More

    rs10767664 Gene Variant in Brain-Derived Neurotrophic Factor Is Associated with Diabetes Mellitus Type 2 in Caucasian Females with Obesity.
    Ann Nutr Metab 2017 9;70(4):286-292. Epub 2017 Jun 9.
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Department of Endocrinology and Nutrition, Hospital Clinico Universitario, University of Valladolid, Valladolid, Spain.
    Background: The role of brain-derived neurotrophic factor (BDNF) variants on diabetes prevalence, basal adipokine levels, body weight, and cardiovascular risk factors remains unclear in obese patients.

    Objective: This study is aimed at analyzing the effects of rs10767664 BDNF gene polymorphism on diabetes mellitus prevalence, body weight, cardiovascular risk factors, and serum adipokine levels in obese female patients.

    Design: A total of 507 obese women were enrolled in a prospective way. Read More

    Association of Blood Fatty Acid Composition and Dietary Pattern with the Risk of Non-Alcoholic Fatty Liver Disease in Patients Who Underwent Cholecystectomy.
    Ann Nutr Metab 2017 9;70(4):303-311. Epub 2017 Jun 9.
    Department of Food and Nutrition, College of Medicine, Hanyang University, Seoul, South Korea.
    Background/aims: The relationship between diet and non-alcoholic fatty liver disease (NAFLD) in patients with gallstone disease and in those who have a high risk for NAFLD has not been investigated. This study was conducted to investigate the association between the risk of NAFLD and dietary pattern in patients who underwent cholecystectomy. Additionally, we assessed the association between erythrocyte fatty acid composition, a marker for diet, and the risk of NAFLD. Read More

    Association between Leptin, Adiponectin, and Leptin/Adiponectin Ratio with Clustered Metabolic Risk Factors in Portuguese Adolescents: The LabMed Physical Activity Study.
    Ann Nutr Metab 2017 9;70(4):321-328. Epub 2017 Jun 9.
    Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal.
    Introduction: Circulating leptin and adiponectin levels have been associated with impaired vascular function, insulin resistance, and acute cardiovascular evens. This study aimed to evaluate the associations of leptin, adiponectin, and the leptin/adiponectin (L/A) ratio with a clustering of metabolic risk factors (MRF) in adolescents aged 12-18 years.

    Methods: This is a cross-sectional analysis with 529 Portuguese adolescents aged 12-18 years. Read More

    The Effect of Dietary Supplements Containing Green Tea, Capsaicin and Ginger Extracts on Weight Loss and Metabolic Profiles in Overweight Women: A Randomized Double-Blind Placebo-Controlled Clinical Trial.
    Ann Nutr Metab 2017 9;70(4):277-285. Epub 2017 Jun 9.
    Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
    Background: This study was conducted to determine the effects of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles among overweight women.

    Methods: This randomized double-blind placebo-controlled clinical trial was implemented among 50 overweight women. Participants were randomly divided into 2 groups. Read More

    Effects of Weight Loss with and without Exercise on Regional Body Fat Distribution in Postmenopausal Women.
    Ann Nutr Metab 2017 9;70(4):312-320. Epub 2017 Jun 9.
    Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD, USA.
    Background/aims: The purpose was to determine whether lifestyle interventions have different effects on regional fat in women with normal glucose tolerance vs. impaired glucose tolerance (NGT vs. IGT). Read More

    Clustered Cardiovascular Risk Factors Are Associated with Inflammatory Markers in Adolescents.
    Ann Nutr Metab 2017 9;70(4):259-267. Epub 2017 Jun 9.
    School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Brazil.
    Background: Clusters of cardiovascular risk (CVR) factors are associated with an increased risk of developing cardiovascular diseases (CVDs). This cross-sectional study assessed the associations between classic CVR factor clusters and inflammatory markers in Brazilian adolescents.

    Methods: Measurements included anthropometric, clinical and biochemical parameters and selected inflammatory markers in 487 adolescents (236 boys/251 girls; 12. Read More

    The Role of Hydrolyzed Formula in Allergy Prevention.
    Ann Nutr Metab 2017 19;70 Suppl 2:38-45. Epub 2017 May 19.
    Department of Pediatrics, Epidemiology and Biostatistics and Philip R. Lee Institute for Health Policy Studies, University of California San Francisco, San Francisco, CA, USA.
    Asthma, eczema, food allergy, and allergic rhinitis are some of the most common pediatric, chronic conditions in the world. Breastfeeding is the optimal way to feed all infants. For those infants who are exposed to infant formula, some studies suggest that certain partially hydrolyzed or extensively hydrolyzed formulas may decrease the risk of allergic disease compared to nonhydrolyzed formulas for children with a family history of atopic disease. Read More

    Breastfeeding, Childhood Asthma, and Allergic Disease.
    Ann Nutr Metab 2017 19;70 Suppl 2:26-36. Epub 2017 May 19.
    Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
    The worldwide prevalence of childhood asthma has been increasing considerably, and the protection afforded by breastfeeding in its development has been the subject of controversy for more than 80 years. Previous systematic reviews have generally found a protective effect of breastfeeding on allergic outcomes, although many studies have methodological limitations. Although breastfeeding is protective against lower respiratory tract infection during infancy, such protection has not been demonstrated for asthma in all studies. Read More

    Mechanisms of Tolerance Induction.
    Ann Nutr Metab 2017 19;70 Suppl 2:7-24. Epub 2017 May 19.
    Division of Allergy and Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, Kravis Children's Hospital, New York, NY, USA.
    Food allergy results from failure in oral tolerance that usually occurs in infancy or early childhood. Exposure to peanut and hen's egg via the inflamed and disrupted epithelial barrier in children with severe atopic dermatitis is a risk factor for the development of allergy to these foods and supports the hypothesis that epicutaneous exposure in the absence of oral feeding is an important pathway of allergic IgE sensitization in infants. In recent years, the collective evidence has pointed toward the protective effect of an early feeding with peanut and egg in children with eczema, taking advantage of the pathways underlying oral tolerance to counteract epicutaneous exposure. Read More

    Introduction of Complementary Foods to Infants.
    Ann Nutr Metab 2017 19;70 Suppl 2:47-54. Epub 2017 May 19.
    Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
    While earlier food allergy prevention strategies implemented avoidance of allergenic foods in infancy, the current paradigm is shifting from avoidance to controlled exposure. This review focuses on the outcome of recent randomized controlled trials, which have examined the early introduction of allergenic foods for allergy prevention, and discusses the implementation of results in clinical practice. In infants at high risk of allergic disease, there is now direct evidence that regular early peanut consumption will reduce the prevalence of peanut allergy, compared to avoidance. Read More

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