2,369 results match your criteria Annals of Nutrition and Metabolism[Journal]
Ann Nutr Metab 2018 20;72 Suppl 2:11-16. Epub 2018 Jun 20.
Background: Serious and often fatal acute kidney injury (AKI) is frequently seen after major surgery, local and remote organ damage, and sepsis. It is associated with uncontrolled inflammation, and is usually diagnosed only after the kidneys have gone through significant and often irreversible damage.
Summary: During our work involving another type of kidney disease that leads to acid-base disorders of the blood, we unexpectedly found high levels of a protein called the P2Y14 "purinergic" receptor, in specialized kidney epithelial cells called intercalated cells (ICs). Read More
Ann Nutr Metab 2018 20;72 Suppl 2:3-7. Epub 2018 Jun 20.
Recent experiments using optogenetic tools allow the identification and functional analysis of thirst neurons and vasopressin producing neurons. Two major advances provide a detailed anatomy of taste for water and arginine-vasopressin (AVP) release: (1) thirst and AVP release are regulated not only by the classical homeostatic, intero-sensory plasma osmolality negative feedback, but also by novel, extero-sensory, anticipatory signals. These anticipatory signals for thirst and vasopressin release converge on the same homeostatic neurons of circumventricular organs that monitor the composition of the blood; (2) acid-sensing taste receptor cells (which express polycystic kidney disease 2-like 1 protein) on the tongue that were previously suggested as the sour taste sensors also mediate taste responses to water. Read More
Ann Nutr Metab 2018 20;72 Suppl 2:8-10. Epub 2018 Jun 20.
As a preventive strategy, increased water intake is often recommended to women affected by recurrent cystitis; however, clinical data are sparse and conflicting. This review evaluates the preventive approaches used as alternatives to obtain relief from the burden of cystitis and focuses on the effect of fluid intake on urinary tract infection. Read More
Ann Nutr Metab 2018 20;72 Suppl 2:33-38. Epub 2018 Jun 20.
Polycystic kidney disease (PKD) is a group of monogenetic conditions characterised by the progressive accumulation of multiple renal cysts and hypertension. One of the earliest features of PKD is a reduction in urinary concentrating capacity that impairs extracellular fluid conservation. Urinary concentrating impairment predisposes PKD patients to periods of hypohydration when fluid loss is not adequately compensated by fluid intake. Read More
Ann Nutr Metab 2018 20;72 Suppl 2:17-20. Epub 2018 Jun 20.
Background: Diabetic nephropathy has become the most common cause of chronic kidney disease (CKD). Despite the progress accomplished in therapy, the prevalence of renal disorders remains high. Some modifiable factors driving the increase in incidence of CKD, in diabetes and other settings, might have been overlooked. Read More
Ann Nutr Metab 2018 20;72 Suppl 2:28-32. Epub 2018 Jun 20.
Background: Chronic Kidney Disease (CKD) is a major public health problem and is increasingly being recognized as an important driver of costs in all health care systems. The diversity of outcomes for people living with CKD is in part due to variability in biology, access to care, environmental factors, and health care system differences. The International Society of Nephrology (ISN), working in collaboration with its partners, has evolved into a philanthropic organization, from a traditional medical society, committed to a vision that sees "a future where all people have access to sustainable kidney health". Read More
Ann Nutr Metab 2018 20;72 Suppl 2:39-44. Epub 2018 Jun 20.
Ann Nutr Metab 2018 20;72 Suppl 2:21-27. Epub 2018 Jun 20.
Department of Clinical Sciences, Lund University, Malmö, Sweden.
Background: Type 2 diabetes, chronic kidney disease (CKD) and its cardiovascular complications are increasing as health problems worldwide. These diseases are interrelated with overlapping occurrence and once diabetes is established, the risk of cardiorenal disease is dramatically elevated. Thus, a search for unifying modifiable risk factors is key for effective prevention. Read More
Ann Nutr Metab 2018 19;72 Suppl 2:1-2. Epub 2018 Jun 19.
Ann Nutr Metab 2018 Jun 7;73(1):44-53. Epub 2018 Jun 7.
Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, Harbin, China.
Background/aims: Elevation of plasma sulfur-containing amino acids (SAAs) is generally associated with higher body mass index (BMI) and unfavorable lipid profiles. It is not known how dietary SAAs relate to these associations in humans.
Methods: A convenient tool named internet-based dietary questionnaire for Chinese (IDQC) was used to estimate dietary SAAs intake. Read More
Ann Nutr Metab 2018 Jun 7;73(1):30-43. Epub 2018 Jun 7.
Division of Human Nutrition, Wageningen University and Research Centre, Wageningen, the Netherlands.
Background: Dietary reference values for folate intake vary widely across Europe.
Methods: MEDLINE and Embase through November 2016 were searched for data on the association between folate intake and biomarkers (serum/plasma folate, red blood cell [RBC] folate, plasma homocysteine) from observational studies in healthy adults and elderly. The regression coefficient of biomarkers on intake (β) was extracted from each study, and the overall and stratified pooled β and SE (β) were obtained by random effects meta-analysis on a double log scale. Read More
Ann Nutr Metab 2018 May 29;73(1):19-29. Epub 2018 May 29.
Faculty of Health Sciences, University Fernando Pessoa, Porto, Portugal.
Identifying the underlying child-eating behaviours that contribute to weight differences across growth has been a constant challenge. This report reviews the various literature approaches for assessing appetite regulation. In doing so, it attempts to understand how appetite control develops and determines the eating habits in early childhood, and its effects on children's weight status. Read More
Ann Nutr Metab 2018 May 29;73(1):10-18. Epub 2018 May 29.
Faculty of Health Sciences, University of Primorska, Koper, Slovenia.
Background/aims: Hyperglycemia may influence the hydration status in diabetic individuals. During exercise, type 1 diabetes mellitus (T1DM) individuals may be challenged by a higher risk of dehydration due to a combination of fluid losses from sweat and increased urine output via glycosuria. So far, no study has characterised spontaneous fluid intake in T1DM individuals during active trainings. Read More
Ann Nutr Metab 2018 May 22;73(1):2-9. Epub 2018 May 22.
Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Objective: Hypermetabolism based on measurements of resting energy expenditure (REE) is suggested to be a potential biomarker for predicting the clinical outcomes of some diseases. We aimed to evaluate the potential value of hypermetabolism for predicting the short-term (28-day) mortality of patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF).
Methods: A total of 105 HBV-ACLF patients, 30 chronic hepatitis B (CHB) patients and 30 healthy controls (HCs) were included in this study. Read More
Ann Nutr Metab 2018 8;72(4):336-344. Epub 2018 May 8.
Department of Emergency Medicine, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Background/aims: Muscle mass depletion has been suggested to predict morbidity and mortality in various diseases. However, it is not well known whether muscle mass depletion is associated with poor outcome in sepsis. We hypothesized that muscle mass depletion is associated with poor outcome in sepsis. Read More
Ann Nutr Metab 2018 4;72(4):316-328. Epub 2018 May 4.
Bill and Melinda Gates Foundation, Seattle, Washington, USA.
Background: Adolescents, comprised of 10-19 year olds, form the largest generation of young people in our history. There are an estimated 1.8 billion adolescents in the world, with 90% residing in low- and middle-income countries. Read More
Ann Nutr Metab 2018 4;72(4):329-335. Epub 2018 May 4.
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Background/aims: The effect of low carbohydrate diet on human health is still controversial. Whole grain, which is carbohydrate rich in fiber, has protective effects on human health. Thus, we assumed that intake of carbohydrate to fiber ratio has an important role in human health. Read More
Ann Nutr Metab 2018 27;72(4):307-315. Epub 2018 Apr 27.
Department of Pediatrics, Hospital Gelderse Vallei, Ede, the Netherlands.
Background: What is the appropriate time to start complementary feeding for preterm infants? The answer to this question is yet under debate. The timing of initiating complementary feeding may be associated with overweight in term infants. This systematic review aimed to study the effect of the timing of initiating complementary feeding on overweight in preterm infants. Read More
Ann Nutr Metab 2018 25;72(4):296-306. Epub 2018 Apr 25.
Functional bowel disorders (FBD) resemble a group of diseases of the gastrointestinal (GI) tract that are without a clear pathogenesis; the best known is probably the "irritable bowel syndrome" (IBS). Only recently we have been able to explore the role of the gut microbiota in FBD due to progress in microbiological analytic techniques. There are different ways to explore the role of the gut microbiota and its dysbiosis in FBD. Read More
Ann Nutr Metab 2018 25;72(4):287-295. Epub 2018 Apr 25.
Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background/aims: This prospective study is aimed at examining the predictive value of high-sensitivity C-reactive protein (hs-CRP) for coronary heart disease (CHD) events and microvascular complications of type 2 diabetes mellitus (T2DM).
Methods: A population-based study (NCT02958579) was conducted on 1,301 participants with T2DM (mean follow-up of 7.5 years). Read More
Ann Nutr Metab 2018 12;72(4):272-278. Epub 2018 Apr 12.
Adjunct Professor of the Department of Pediatrics, Federal University of São Paulo/São Paulo School of Medicine, São Paulo, Brazil.
Background/aims: This study aimed to identify a possible association among high birth weight with overweight/obesity, high arterial blood pressure, dyslipidemia, and insulin resistance in children and adolescents.
Methods: This is a cross-sectional study with 719 children and adolescents (6-12 years) stratified according to birth weight (low birth weight [LBW] <2,500 g, adequate birth weight [ABW] 2,500-3,999 g, and high birth weight [HBW] ≥4,000 g). Data collected were anthropometric data, arterial blood pressure levels, lipid profile, and insulin resistance (fasting glucose and insulin, used to calculate homeostatic model assessment-IR). Read More
Ann Nutr Metab 2018 12;72(4):279-286. Epub 2018 Apr 12.
Federal University of São Paulo, São Paulo, Brazil.
Background: Deregulation of orexigenic and anorexigenic pathways occurs among adolescents with obesity. Alpha-melanocyte-stimulating hormone (α-MSH) is a key catabolic mediator of energy homeostasis and an important anorexigenic neuropeptide in the control of energy balance and thermogenesis. However, it was not well explored if α-MSH can modulate long-term weight loss therapy responses in a dependent manner according to its concentration. Read More
Ann Nutr Metab 2018 10;72 Suppl 3:46. Epub 2018 Apr 10.
Ann Nutr Metab 2018 10;72 Suppl 3:47-54. Epub 2018 Apr 10.
MRC Unit The Gambia at LSHTM, Banjul, Gambia.
Undernutrition in both its acute and chronic forms (wasting and stunting) is strongly inversely correlated with the wealth of nations. Consequently, as many low- and middle-income countries (LMICs) achieve economic advancement and pass through the so-called "nutrition transition," their rates of undernutrition decline. Many countries successfully achieved the Millennium Development Goal of halving undernutrition and whole continents have been transformed in recent decades. Read More
Ann Nutr Metab 2018 10;72 Suppl 3:24. Epub 2018 Apr 10.
Ann Nutr Metab 2018 10;72 Suppl 3:25-31. Epub 2018 Apr 10.
As technology has advanced, survival rates of preterm infants have improved dramatically. Human milk was the primary source of enteral nutrition during the early days of neonatology, but the HIV/AIDS epidemic resulted in an increased use of preterm formula. More recently, the benefits of human milk were rediscovered, resulting in increased use of donor human milk as well. Read More
Ann Nutr Metab 2018 9;72 Suppl 3:33-45. Epub 2018 Apr 9.
In view of the dramatic rise in the prevalence of food allergy globally, effective prevention strategies have become a public health priority. Several models have emerged around the etiology of food allergy, including the hygiene hypothesis, dual allergen exposure hypothesis, and vitamin D hypothesis. These form the basis for current and potential prevention strategies. Read More
Ann Nutr Metab 2018 9;72 Suppl 3:55. Epub 2018 Apr 9.
Ann Nutr Metab 2018 9;72 Suppl 3:6-7. Epub 2018 Apr 9.
Ann Nutr Metab 2018 9;72 Suppl 3:56-64. Epub 2018 Apr 9.
Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
This paper reviews information on why the nutrition of older children (5-9 years) and adolescents (10-19 years) is important and the consequences that it can have over generations. Developing countries still face a high burden of undernutrition and anemia, while the burden of overweight and obesity is on the rise in both developing and developed countries. There are evidence-based interventions which can improve the nutritional status and these include interventions for a balanced and diverse diet and micronutrient supplementation, especially iron and multiple micronutrient supplementation where there is sufficient evidence to reduce anemia. Read More
Ann Nutr Metab 2018 9;72 Suppl 3. Epub 2018 Apr 9.
Ann Nutr Metab 2018 9;72 Suppl 3:13-23. Epub 2018 Apr 9.
Currently, it is impossible to think of modern healthcare that ignores evidence-based medicine (EBM), a concept which relies on 3 pillars: individual clinical expertise, the values and desires of the patient, and the best available research. However, EBM is not perfect. Clinical research is also far from being perfect. Read More
Ann Nutr Metab 2018 29;72(4):259-264. Epub 2018 Mar 29.
Department of Pediatrics, Albert Szent-Györgyi Health Center, University of Szeged, Szeged, Hungary.
Background/aims: The prevalence of overweight and obesity in children and adolescents is increasing worldwide, and this condition is a risk factor for cardiovascular mortality. The aim of this study was to assess the prevalence of overweight and obesity among the 3-18-year-old population in Szolnok City and the surrounding areas.
Methods: Anthropometric data from healthy, white individuals recruited from nursery, elementary, and secondary schools were used to assess the prevalence of obesity and overweight in Szolnok City and the surrounding area, Jász-Nagykun-Szolnok county, Hungary. Read More
Ann Nutr Metab 2018 29;72(4):265-271. Epub 2018 Mar 29.
Department of Internal Medicine F-Recanati, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Background: Vitamin B12 deficiency is associated with hematological, neurological, and cardiovascular consequences. Epidemiologic data on these related illnesses indicate gender differences.
Methods: A cross-sectional study was designed to examine gender differences in vitamin B12 deficiency among a healthy population. Read More
Ann Nutr Metab 2018 27;72(3):248-254. Epub 2018 Mar 27.
Experimental Nutrition (retired), Maastricht University, Maastricht, the Netherlands.
Current discussion of the importance of food fats in the risk of coronary heart disease (CHD) often suffers from preconceptions, misunderstandings, insufficient knowledge, and selective reasoning. As a result, the sustained controversy about dietary fat recommendations can be contradictory and confusing. To clarify some of these issues, the International Expert Movement to Improve Dietary Fat Quality in cooperation with the International Union of Nutritional Sciences (IUNS) organized a symposium at the 21st meeting of the IUNS, October 17, 2017, Buenos Aires, Argentina, to summarize the key scientific evidence underlying the controversy on the relationship between the saturated and unsaturated fat consumption and CHD risk. Read More
Ann Nutr Metab 2018 13;72(3):179-192. Epub 2018 Mar 13.
Gynecology Service, Virgen de la Arrixaca Hospital, Murcia, Spain.
Background: To what extent does the circulating 25-hydroxyvitamin D (25[OH]D) concentration help to meet the physiological needs of humans is an ongoing subject of debate. Remaining unexposed to the sun to reduce melanoma cancer risk, current lifestyle with less out door activities, and increasing obesity rates, which in turn increases the storage of vitamin D in the adipose tissue, are presumably factors that contribute to the substantial upsurge in the prevalence of vitamin D deficiency in humans. Since evidence is lacking regarding the appropriate cut-off points to define vitamin D status during pregnancy, references used to establish the intake recommendations and vitamin D content of prenatal vitamin supplements are quite conservative. Read More
Ann Nutr Metab 2018 8;72(3):241-247. Epub 2018 Mar 8.
Department of Nephrology and Hypertension, Galilee Medical Center, Nahariya, Israel.
Background/aims: This study is the first of its kind to examine the impact of the Ramadan fasting on hydration status, plasma brain natriuretic peptide (BNP) levels, and kidney function in chronic kidney disease (CKD) patient.
Methods: This prospective cohort study included 2 groups of patients with CKD grades 2-4: thirty-one Muslim patients who fasted the month of Ramadan (fasting group) and 26 Muslim patients who did not fast (control group). One week before the Ramadan fast, in the last week of the month of Ramadan (4 weeks), and 4 weeks after the end of the Ramadan month (8 weeks), hydration status and blood analysis of urea, creatinine and BNP levels were measured. Read More
Ann Nutr Metab 2018 8;72(3):231-240. Epub 2018 Mar 8.
Backgrounds/aims: This study was aimed at understanding the relationship between plasma amino acids and protein malnutrition and at determining whether amino acid supplementation associated with malnutrition and growth improves linear growth in growing rats.
Methods: Body length and plasma amino acids were measured in young male rats that were fed the following diet for 3 weeks, mimicking a low and imbalanced protein diets based on maize, a major staple consumed in developing countries: a 70% calorically restricted cornmeal-based diet (C), C + micronutrients (CM), CM + casein (CMC), CM + soy protein (CMS) or CMS + 0.3% lysine. Read More
Ann Nutr Metab 2018 8;72(3):210-222. Epub 2018 Mar 8.
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Background: A wealth of information on the functional roles of docosahexaenoic acid (DHA) and arachidonic acid (ARA) from cellular, animal, and human studies is available. Yet, there remains a lack of cohesion in policymaking for recommended dietary intakes of DHA and ARA in early life. This is predominantly driven by inconsistent findings from a relatively small number of randomised clinical trials (RCTs), which vary in design, methodology, and outcome measures, all of which were conducted in high-income countries. Read More
Ann Nutr Metab 2018 8;72(3):223-230. Epub 2018 Mar 8.
Division of General Internal Medicine, University of California, San Francisco, California, USA.
Background/aims: Asian Indians have a high prevalence of vitamin D deficiency and metabolic syndrome. Vitamin D deficiency is associated with an increased risk of cardiovascular disease and diabetes.
Methods: We performed a cross-sectional study of 150 Asian Indians (50% male) from the San Francisco Bay Area. Read More
Ann Nutr Metab 2018 8;72(3):193-201. Epub 2018 Mar 8.
Background: The International Union of Nutritional Sciences held its 21st International Congress of Nutrition in October 2017 in Buenos Aires, Argentina under the theme - From Sciences to Nutrition Security. In addition to multiple sessions on food systems and their links to diet, nutrition and health, the Congress closing lecture focused on the need to transform food systems so as to increase their capacity to provide healthy diets, making a call for greater involvement of nutrition scientists.
Summary: This article presents the main messages of that lecture, providing (i) an overview of global nutrition trends and their links to diets, food environments and food systems, (ii) a synopsis of the current global momentum for food system transformation and (iii) the need for nutrition scientists to leverage this momentum in terms of increased evidence generation and policy advocacy. Read More
Ann Nutr Metab 2018 8;72(3):202-209. Epub 2018 Mar 8.
Background: This analysis sets out an overview of an IUNS presentation of a European clinician's assessment of the challenges of coping with immediate critical clinical problems and how to use metabolic and a mechanistic understanding of disease when developing nutritional policies.
Summary: Critically ill malnourished children prove very sensitive to both mineral and general nutritional overload, but after careful metabolic control they can cope with a high-quality, energy-rich diet provided their initial lactase deficiency and intestinal atrophy are taken into account. Detailed intestinal perfusion studies also showed that gastroenteritis can be combatted by multiple frequent glucose/saline feeds, which has saved millions of lives. Read More
Ann Nutr Metab 2018 6;72(2):172. Epub 2018 Mar 6.
Ann Nutr Metab 2018 21;72(2):161-171. Epub 2018 Feb 21.
Department of Public Health, Faculty of Health Sciences, Medical University of Bialystok, Bialystok, Poland.
Background/aims: The study was carried out to evaluate the changes in the eating habits and lipid parameters in a 21-year follow-up on a group of 435 men living in Poland.
Methods: The studied population was composed of the same subjects: a group of men who were first studied in the years 1987-1989 and in 2008-2010. The following data was gathered: body mass, body mass index (BMI), total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglyceride concentration in blood serum. Read More
Ann Nutr Metab 2018 21;72(2):151-160. Epub 2018 Feb 21.
Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
Objective: This study was conducted to evaluate the effects of vitamin D supplementation on the recurrence and metabolic status of patients with cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3).
Methods: This randomized, double-blind, placebo-controlled trial was carried out among 58 women diagnosed with CIN2/3. Participants were randomly assigned into 2 groups to receive either 50,000 IU vitamin D3 (n = 29) or placebo (n = 29) every 2 weeks for 6 months. Read More
Ann Nutr Metab 2018 14;72 Suppl 1:1-76. Epub 2018 Feb 14.
Ann Nutr Metab 2018 6;72(2):149-150. Epub 2018 Feb 6.
Department of Biochemistry and Molecular Biology, Medical College, Nantong University, Nantong, China.
Ann Nutr Metab 2018 30;72(2):134-141. Epub 2018 Jan 30.
Hydration Science Lab, University of Arkansas, Fayetteville, Arkansas, USA.
Aim: To examine the validity of published resting energy expenditure (REE) equations in Greek adults, and if indicated, develop new cohort-specific predictive REE equations.
Methods: Indirect calorimetry and anthropometric data were obtained from 226 adult volunteers of diverse age groups and body mass index ranges (18-60 years, 16.6-67. Read More
Ann Nutr Metab 2018 25;72(2):117-125. Epub 2018 Jan 25.
Department of Internal Medicine, Maastricht University, Maastricht, the Netherlands.
Aims: To evaluate whether participant characteristics and way of expressing circulating fatty acids (FA) influence the strengths of associations between self-reported intake and circulating levels of linoleic acid (LA), alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
Methods: Cross-sectional analyses were performed in pooled data from the CODAM (n = 469) and Hoorn (n = 702) studies. Circulating FA were measured by gas liquid chromatography and expressed as proportions (% of total FA) and concentrations (µg/mL). Read More
Ann Nutr Metab 2018 30;72(2):142-148. Epub 2018 Jan 30.
Background/aims: Previous studies have suggested that leptin was associated with atherosclerosis and involved in inflammation. Gender differences between leptin and inflammatory markers have been evaluated less in untreated patients with stable coronary artery disease (CAD).
Methods: In this study, a total of 394 consecutive Chinese patients who received coronary artery angiography were enrolled, including 243 patients with CAD and 151 non-CAD controls. Read More