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    1213 results match your criteria Annals of Noninvasive Electrocardiology [Journal]

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    Symptomatic arrhythmia in the form of multiple premature ventricular extrasystoles as the first symptom of polymyositis.
    Ann Noninvasive Electrocardiol 2018 Jan 30. Epub 2018 Jan 30.
    epartment of Cardiology, Pomeranian Medical University, Szczecin, Poland.
    Polymyositis (PM) is an autoimmune disease characterized by the involvement of multiple internal organs, including the cardiovascular system. The involvement of heart is observed in up to 75% of patients with PM. Conduction and rhythm disorders are one of the most common cardiological abnormalities in these patients. Read More

    Baseline fragmented QRS increases the risk of major arrhythmic events in hypertrophic cardiomyopathy: Systematic review and meta-analysis.
    Ann Noninvasive Electrocardiol 2018 Jan 24. Epub 2018 Jan 24.
    Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
    Background: Fragmented QRS reflects disturbances in the myocardium predisposing the heart to ventricular tachyarrhythmias. Recent studies suggest that fragmented QRS (fQRS) is associated with worse major arrhythmic events in hypertrophic cardiomyopathy (HCM). However, a systematic review and meta-analysis of the literature has not been done. Read More

    The analysis of the parameters of 24-hr ECG Holter monitoring in patients with blood neoplasms undergoing high-dose chemotherapy and stem cell transplantation.
    Ann Noninvasive Electrocardiol 2018 Jan 24. Epub 2018 Jan 24.
    Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland.
    Background: Hematopoietic stem cell transplantation (HSCT) is a widely used procedure in the treatment of malignant diseases, including blood neoplasms and has increased survival in hematological diseases. The aim of the study was to analyze parameters of 24-hr ECG monitoring in patients with selected blood neoplasms in whom the procedure of hematopoietic stem cell transplantation was performed.

    Methods: The study group consisted of 64 adults diagnosed with hematologic cancer qualified for HSCT with the previous high dose chemotherapy (HDC). Read More

    Acute coronary syndrome of very unusual etiology.
    Ann Noninvasive Electrocardiol 2018 Jan 21. Epub 2018 Jan 21.
    Faculty of Medicine and Life Sciences, Heart Center, Tampere University Hospital, University of Tampere, Tampere, Finland.
    Aortitis is one of many possible manifestations of tertiary syphilis. Aortic disease is the most common of all cardiovascular syphilitic lesions. Aortic diseases caused by tertiary syphilis include aortitis, aortic root dilation, aneurysm formation, aortic regurgitation and coronary ostial stenosis. Read More

    Coarse fibrillatory waves in atrial fibrillation predict success of electrical cardioversion.
    Ann Noninvasive Electrocardiol 2017 Dec 22. Epub 2017 Dec 22.
    Department of Cardiology, Bedford Hospital, Bedford, UK.
    Background: To determine whether the presence of "coarse" fibrillatory waves (Fw) seen on surface ECGs of patients with persistent atrial fibrillation (AF) predict maintenance of sinus rhythm (SR) at 6 weeks after electrical cardioversion (ECV).

    Methods: Preprocedure ECGs from 94 consecutive patients with persistent AF scheduled to undergo ECV at a single centre were classified as having coarse Fw (≥0.1 mV) or fine Fw (<0. Read More

    Comparison of the predictive accuracy of four different ECG algorithms in identification of true ablation site for the idiopathic right ventricular outflow tract tachycardias.
    Ann Noninvasive Electrocardiol 2017 Dec 22. Epub 2017 Dec 22.
    Turkiye Yuksek Ihtisas Research and Education Hospital, Ankara, Turkey.
    Background: We aimed to investigate the accuracy of four algorithms in prediction of right ventricular outflow tract (RVOT) tachycardias in patients who successfully underwent radiofrequency catheter ablation.

    Methods: Four algorithms; two with easy-applicability and having a memorable design (Dixit and Joshi), and two with more complex and detailed design (Ito and Zhang) were compared according to the predictive accuracy.

    Results: Among 99 patients (mean age 36. Read More

    Noninvasive phase mapping of persistent atrial fibrillation in humans: Comparison with invasive catheter mapping.
    Ann Noninvasive Electrocardiol 2017 Dec 22. Epub 2017 Dec 22.
    Asklepios Klinik St. Georg, Hamburg, Germany.
    Background: A novel noninvasive epicardial and endocardial electrophysiology system (NEEES) to identify electrical rotors and focal activity in patients with atrial fibrillation (AF) was recently introduced. Comparison of NEEES data with results from invasive mapping is lacking.

    Methods: Six male patients (59 ± 11 years) with persistent AF underwent cardiac mapping with the NEEES, which included the creation of isopotential and phase maps. Read More

    Unshielded magnetocardiography: Repeatability and reproducibility of automatically estimated ventricular repolarization parameters in 204 healthy subjects.
    Ann Noninvasive Electrocardiol 2017 Dec 20. Epub 2017 Dec 20.
    Biomagnetism and Clinical Physiology International Center, Catholic University of Sacred Heart, Rome, Italy.
    Background: Magnetocardiographic mapping (MCG) provides quantitative assessment of the magnetic field (MF) induced by cardiac ionic currents, is more sensitive to tangential currents, and measures vortex currents undetectable by ECG, with higher reported sensitivity of MCG ventricular repolarization (VR) parameters for earlier detection of acute myocardial ischemia. Aims of this study were to validate the feasibility of in-hospital unshielded MCG and to assess repeatability and reproducibility of quantitative VR parameters, considering also possible gender- and age-related variability.

    Methods: MCG of 204 healthy subjects [114 males-mean age 43. Read More

    Relation between electrical and mechanical dyssynchrony in patients with left bundle branch block: An electro- and vectorcardiographic study.
    Ann Noninvasive Electrocardiol 2017 Dec 18. Epub 2017 Dec 18.
    Ghent University Hospital, Heart Center, Ghent, Belgium.
    Background: Current guidelines select patients for cardiac resynchronization therapy (CRT) mainly on electrocardiographic parameters like QRS duration and left bundle branch block (LBBB). However, among those LBBB patients, heterogeneity in mechanical dyssynchrony occurs and might be a reason for nonresponse to CRT. This study assesses the relation between electrocardiographic characteristics and presence of mechanical dyssynchrony among LBBB patients. Read More

    S-R difference in V1-V2 is a novel criterion for differentiating the left from right ventricular outflow tract arrhythmias.
    Ann Noninvasive Electrocardiol 2017 Dec 10. Epub 2017 Dec 10.
    Department of Cardiology, Adana Numune Training and Research Hospital, Health Sciences University, Adana, Turkey.
    Aim: The correct estimation of the VA origin as RVOT or LVOT results in reduced ablation duration reduced radiation exposure and decreased number of vascular access. In our study, we aimed to detect the predictive value of S-R difference in V1-V2 for differentiating the left from right ventricular outflow tract arrhythmias.

    Methods: We included 123 patients with symptomatic frequent premature ventricular outflow tract contractions who underwent successful catheter ablation (70 male, 53 female; mean age 46. Read More

    Heart rate recovery fast-to-slow phase transition: Influence of physical fitness and exercise intensity.
    Ann Noninvasive Electrocardiol 2017 Dec 8. Epub 2017 Dec 8.
    Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
    Background: Postexercise heart rate (HR) recovery presents an exponential decay, with two distinct phases: a fast phase, characterized by abrupt decay of HR, and determined by parasympathetic reactivation; and a slow phase, characterized by gradual decay of HR, and predominantly determined by sympathetic withdrawal. Although several methods have been proposed to assess postexercise HR recovery, none of those methods selectively assesses the time of transition from the fast to the slow phase of the HR recovery curve (HRR), and the magnitude of decay prior to (HRR) and after this point (HRR). Therefore, the aim of the present study was to propose a method to identify HRR, HRR, and HRRand to verify the effects of exercise intensity and physical fitness on such parameters. Read More

    Repetitive-incessant electrical storm triggered by early repolarization.
    Ann Noninvasive Electrocardiol 2017 Dec 5. Epub 2017 Dec 5.
    Metropolitan Hospital, Athens, Greece.
    Early repolarization syndrome (ERS) was originally considered a normal variant with benign outcome. However, recent studies have demonstrated that it can be linked to a considerable risk of life-threatening arrhythmias and sudden cardiac death. We report a case with an extraordinary, extremely malignant clinical expression of ERS refractory to all antiarrhythmic drugs including quinidine. Read More

    Is myocardial repolarization duration associated with repolarization heterogeneity?
    Ann Noninvasive Electrocardiol 2017 Dec 2. Epub 2017 Dec 2.
    General Electric Healthcare, Milwaukee, WI, USA.
    Background: Dispersion of repolarization is theorized as one mechanism by which myocardial repolarization prolongation causes lethal torsades de pointes, (TdP). Our primary purpose was to determine whether prolongation of myocardial repolarization as measured by the heart rate-corrected J-to-T peak interval (JTpkc), is associated with repolarization heterogeneity as measured by transmural dispersion, defined as the median duration from the peak to the end of the T wave (TpTe).

    Methods: A retrospective cohort study was performed at a single urban tertiary ED from July 2011-September 2012. Read More

    Late-onset severe long QT syndrome.
    Ann Noninvasive Electrocardiol 2017 Nov 30. Epub 2017 Nov 30.
    University Clinic of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
    We report a case of torsades de pointes arrhythmia as the first manifestation of congenital Long QT syndrome in a 77-year-old man with family history of sudden unexplained death. This case illustrates the importance of vigilant clinical assessment and genetic counseling in families with sudden death in order to identify properly asymptomatic relatives at risk for cardiac events. It also demonstrates that Long QT syndrome can still manifest with potentially fatal arrhythmias late in life in previously asymptomatic elderly patients. Read More

    Narrowing filtered QRS duration on signal-averaged electrocardiogram predicts outcomes in cardiac resynchronization therapy patients with nonischemic heart failure.
    Ann Noninvasive Electrocardiol 2017 Nov 30. Epub 2017 Nov 30.
    Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
    Background: To evaluate the impact of changes in the filtered QRS duration (fQRS) on signal-averaged electrocardiograms (SAECGs) from pre- to postimplantation on the clinical outcomes in nonischemic heart failure (HF) patients under cardiac resynchronization therapy (CRT).

    Methods: We studied 103 patients with nonischemic HF and sinus rhythm who underwent CRT implantation. SAECGs were obtained within 1 week before and 1 week after implantation and narrowing fQRS was defined as a decrease in fQRS from pre- to postimplantation. Read More

    A case report: Is mexiletine usage effective in the shortening of QTC interval and improving the T-wave alternans in Timothy syndrome?
    Ann Noninvasive Electrocardiol 2017 Nov 30. Epub 2017 Nov 30.
    Department of Pediatric Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital, Istanbul Saglik Bilimleri University, Istanbul, Turkey.
    Timothy syndrome (TS) is a multisystemic disease that occurs because of a mutation in CACN1C gene and is characterized by prolonged QT interval. Mexiletine is a Class 1B antiarrhythmic drug that causes the disappearance of T-wave alternans by shortening QTc and peak-to-end of the T wave. It may block the development of torsades de pointes in a prolonged QT. Read More

    Loperamide cardiotoxicity: "A Brief Review".
    Ann Noninvasive Electrocardiol 2017 Nov 10. Epub 2017 Nov 10.
    Department of Electrophysiology, Staten Island University Hospital, Staten Island, NY, USA.
    Loperamide is a popular antidiarrheal medication that has been used for many years. It is currently gaining more attention among healthcare professionals due to its increasing potential for side effects. At present, it is considered safe enough to be sold over the counter. Read More

    Efficacy and safety of intravenous vernakalant for the rapid conversion of recent-onset atrial fibrillation: A meta-analysis.
    Ann Noninvasive Electrocardiol 2017 Nov 4. Epub 2017 Nov 4.
    Department of Cardiology, Staten Island University Hospital, NY, USA.
    Background: Atrial fibrillation is a common cardiac arrhythmia with increasing prevalence in the aging population. It is a major cause of emergency department visits worldwide. Vernakalant, a relatively new antiarrhythmic drug with selectively preferential effects on the atrial tissue is currently used in many European countries for the termination of recent-onset atrial fibrillation. Read More

    Clinical applications of QT/RR hysteresis assessment: A systematic review.
    Ann Noninvasive Electrocardiol 2018 Jan 30;23(1). Epub 2017 Oct 30.
    Department of Kinesiology, University of Montreal, Montreal, QC, Canada.
    Background: QT/RR hysteresis (QT-hys) is an index of the time accommodation of ventricular repolarization to heart rate changes. This report comprehensively reviews studies addressing QT-hys as a biomarker of medical conditions.

    Methods: This is a secondary analysis of data from a recent systematic review pertaining to methods of assessment of QT-hys. Read More

    Catecholaminergic polymorphic ventricular tachycardia, an update.
    Ann Noninvasive Electrocardiol 2017 Oct 19. Epub 2017 Oct 19.
    Design of Studies and Scientific Writing Laboratory in the ABC Medicine Faculty, Santo André, São Paulo, Brazil.
    Catecholaminergic polymorphic ventricular tachycardia is a rare devastating lethal inherited disorder or sporadic cardiac ion channelopathy characterized by unexplained syncopal episodes, and/or sudden cardiac death (SCD), aborted SCD (ASCD), or sudden cardiac arrest (SCA) observed in children, adolescents, and young adults without structural heart disease, consequence of adrenergically mediated arrhythmias: exercise-induced, by acute emotional stress, atrial pacing, or β-stimulant infusion, even when the electrocardiogram is normal. The entity is difficult to diagnose in the emergency department, given the range of presentations; thus, a familiarity with and high index of suspicion for this pathology are crucial. Furthermore, recognition of the characteristic findings and knowledge of the management of symptomatic patients are necessary, given the risk of arrhythmia recurrence and SCA. Read More

    The effect of head-up tilt upon markers of heart rate variability in patients with atrial fibrillation.
    Ann Noninvasive Electrocardiol 2017 Oct 15. Epub 2017 Oct 15.
    National Heart and Lung Institute, Imperial College, London, United Kingdom.
    Background: Heart rate variability (HRV) analysis is uncommonly undertaken in patients with atrial fibrillation (AF) due to an assumption that ventricular response is random. We sought to determine the effects of head-up tilt (HUT), a stimulus known to elicit an autonomic response, on HRV in patients with AF; we contrasted the findings with those of patients in sinus rhythm (SR).

    Methods: Consecutive, clinically indicated tilt tests were examined for 207 patients: 176 in SR, 31 in AF. Read More

    Heart failure study of multipoint pacing effects on ventriculoarterial coupling: Rationale and design of the HUMVEE trial.
    Ann Noninvasive Electrocardiol 2017 Oct 15. Epub 2017 Oct 15.
    First University Department of Cardiology, Hippokration Hospital, Athens, Greece.
    Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. Read More

    Recurrent extensive anterior myocardial infarction with left and right bundle branch block.
    Ann Noninvasive Electrocardiol 2017 Oct 15. Epub 2017 Oct 15.
    The Cardiovascular Institute of the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning Province, China.
    The diagnosis of myocardial infarction with left bundle branch block is difficult. We report a case of 56-year-old man with old extensive anterior myocardial infarction and left bundle branch block (masked each other). The recurrent myocardial infarction indicated right bundle branch block and first-degree atrioventricular block, making a clear diagnosis of complicated and interesting ECG. Read More

    Brugada phenocopy caused by a compressive mediastinal tumor.
    Ann Noninvasive Electrocardiol 2017 Oct 15. Epub 2017 Oct 15.
    Design of Studies and Scientific Writing Laboratory of the ABC School of Medicine, Santo André, Brazil.
    Recently, it has been shown that even experts in electrocardiography cannot differentiate the electrocardiographic pattern of genuine Brugada syndrome (BrS) from Brugada phenocopy (BrP). For this reason, this differentiation depends on the presence of established criteria both for BrS and BrP. In this manuscript, we present a patient with type 1 Brugada electrocardiographic pattern caused by expansive anterior mediastinal non-Hodgkin's lymphoma (NHL) with mechanical compression on the right ventricular outflow tract. Read More

    Baseline fragmented QRS increases the risk of major arrhythmic events in Brugada syndrome: Systematic review and meta-analysis.
    Ann Noninvasive Electrocardiol 2017 Oct 14. Epub 2017 Oct 14.
    Department of Internal Medicine, University of Michigan Medical School, Michigan Medicine, Ann Arbor, MI, USA.
    Background: Fragmented QRS reflects disturbances in the myocardium predisposing the heart to ventricular tachyarrhythmias. Recent studies suggest that fragmented QRS (fQRS) is associated with major arrhythmic events in Brugada syndrome. However, a systematic review and meta-analysis of the literature has not been done. Read More

    The prognostic significance of early and late right precordial lead (VR) ST-segment elevation in patients with acute anterior myocardial infarction.
    Ann Noninvasive Electrocardiol 2017 Oct 14. Epub 2017 Oct 14.
    Department of Cardiology, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
    Background: The predictive significance of ST-segment elevation (STE) in lead VR in patients with anterior ST-segment elevation myocardial infarction (STEMI) has not been well-understood. In this study, we evaluated the prognostic value of early and late STE in lead VR in patients with anterior STEMI.

    Methods: A total 451 patients with anterior STEMI who treated with primary percutaneous coronary intervention (PPCI) were prospectively enrolled in this study. Read More

    Propensity score matching analysis of the impact of Syntax score and Syntax score II on new onset atrial fibrillation development in patients with ST segment elevation myocardial infarction.
    Ann Noninvasive Electrocardiol 2017 Oct 4. Epub 2017 Oct 4.
    Ataturk Universitesi, Medical School, Department of Cardiology, Erzurum, Turkey.
    Background: New-onset atrial fibrillation (NOAF) is a common complication in the setting of ST segment elevation myocardial infarction (STEMI), and worsened short/long-term prognosis. Several clinical parameters have already been associated with NOAF development. However, relationship between NOAF and coronary artery disease (CAD) severity in STEMI patients is unclear. Read More

    Parathyroid hormone is related to QT interval independent of serum calcium in patients with coronary artery disease.
    Ann Noninvasive Electrocardiol 2017 Sep 26. Epub 2017 Sep 26.
    Columbia University Medical Center, New York, NY, USA.
    Background: Elevated serum parathyroid hormone (PTH) is associated with increased risk of cardiovascular death, including sudden cardiac death, in patients with and without parathyroid disease. In small studies, PTH levels have been associated with changes in cardiac conduction and repolarization. Changes in the corrected QT interval (QTc) in particular are thought to be mediated by the effect of PTH on serum calcium. Read More

    Marked exercise-induced T-wave heterogeneity in symptomatic diabetic patients with nonflow-limiting coronary artery stenosis.
    Ann Noninvasive Electrocardiol 2017 Sep 26. Epub 2017 Sep 26.
    Beth Israel Deaconess Medical Center, Boston, MA, USA.
    Background: T-wave heterogeneity (TWH) independently predicted cardiovascular mortality in Health Survey 2000 based on 12-lead ECGs recorded at rest. We investigated whether TWH is elevated during exercise tolerance testing (ETT) in symptomatic diabetic patients with nonflow-limiting coronary artery stenosis compared to control subjects without diabetes.

    Methods: Cases were all patients (n = 20) with analyzable ECG recordings during both rest and ETT who were enrolled in the Effects of Ranolazine on Coronary Flow Reserve (CFR) in Symptomatic Patients with Diabetes and Suspected or Known Coronary Artery Disease (RAND-CFR) study (NCT01754259); median CFR was 1. Read More

    Main artifacts in electrocardiography.
    Ann Noninvasive Electrocardiol 2017 Sep 20. Epub 2017 Sep 20.
    Design of Studies and Scientific Writing Laboratory at the ABC School of Medicine, Santo André, São Paulo, Brazil.
    Electrocardiographic artifacts are defined as electrocardiographic alterations, not related to cardiac electrical activity. As a result of artifacts, the components of the electrocardiogram (ECG) such as the baseline and waves can be distorted. Motion artifacts are due to shaking with rhythmic movement. Read More

    Postimplantation ventricular ectopic burden and clinical outcomes in cardiac resynchronization therapy-defibrillator patients: a MADIT-CRT substudy.
    Ann Noninvasive Electrocardiol 2017 Sep 20. Epub 2017 Sep 20.
    Heart Research Follow-up Program, University of Rochester Medical Center, Rochester, NY, USA.
    Background: Frequent ventricular ectopy on preimplantation Holter has been associated with attenuated benefit from cardiac resynchronization therapy (CRT). However, it is unclear whether ectopic burden measured post-CRT implantation can be utilized to evaluate long-term prognosis. We aimed to describe the association between post-CRT implantation ectopic burden and subsequent risk of clinical outcomes. Read More

    Myocardial bridging is associated with exercise-induced ventricular arrhythmia and increases in QT dispersion.
    Ann Noninvasive Electrocardiol 2017 Sep 18. Epub 2017 Sep 18.
    The Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.
    Background: A myocardial bridge (MB) has been associated with ventricular arrhythmia and sudden death during exercise. QT dispersion (QTd) is a measure of abnormal repolarization and may predict ventricular arrhythmia. We investigated the frequency of ventricular arrhythmias during exercise and the QTd at rest and after exercise, in patients with an MB compared to a normal cohort. Read More

    Sudden cardiac death in isolated right ventricular hypertrabeculation/noncompaction cardiomyopathy.
    Ann Noninvasive Electrocardiol 2017 Sep 12. Epub 2017 Sep 12.
    Department of Cardiovascular Medicine and Electrophysiology, Staten Island University Hospital, Northwell Health, Staten Island, NY, USA.
    Hypertrabeculation/noncompaction of the myocardium is a rare disorder that involves most commonly the left ventricle of the heart and it has been recognized as a distinct cardiomyopathy by the World Health Organization. However, it is extremely rare for this condition to involve exclusively the right ventricle. We report the cases of three patients who presented with ventricular tachyarrhythmia and sudden cardiac death. Read More

    Specificity of wide QRS complex tachycardia criteria and algorithms in patients with ventricular preexcitation.
    Ann Noninvasive Electrocardiol 2017 Sep 12. Epub 2017 Sep 12.
    First Department of Cardiology, Interventional Electrocardiology and Hypertension, Medical College, Jagiellonian University, Cracow, Poland.
    Background: Despite substantial progress in the field of differentiation between ventricular tachycardia (VT) and supraventricular tachycardia (SVT) with wide QRS complexes, differentiation between VT and preexcited SVT remains largely unresolved due to significant overlap in QRS morphology. Our aim was to assess the specificities of various single ECG criteria and sets of criteria (Brugada algorithm, aVR algorithm, Steurer algorithm, and the VT score) for diagnosis of VT in a sizable cohort of patients with preexcitation.

    Methods: We performed a retrospective study of consecutive accessory pathway ablation procedures to identify preexcited tachycardias. Read More

    Total cosine R-to-T for predicting ventricular arrhythmic and mortality outcomes: A systematic review and meta-analysis.
    Ann Noninvasive Electrocardiol 2017 Sep 12. Epub 2017 Sep 12.
    Department of Cardiology, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
    Background: The total cosine R-to-T (TCRT), a vectorcardiographic marker reflecting the spatial difference between the depolarization and repolarization wavefronts, has been used to predict ventricular tachycardia/fibrillation (VT/VF) and sudden cardiac death (SCD) in different clinical settings. However, its prognostic value has been controversial.

    Objective: This systematic review and meta-analysis evaluated the significance of TRCT in predicting arrhythmic and/or mortality endpoints. Read More

    Pregbalin induced recurrent syncopal attacks with prolong QT interval.
    Ann Noninvasive Electrocardiol 2017 Aug 30. Epub 2017 Aug 30.
    Department of Cardiology, Faculty of Medicine, Karabuk University, Karabuk, Turkey.
    Long QT syndrome may lead to fatal dysrhythmia. Prolongation of QT interval due to pregabalin has been shown in rats and no data is available in humans. We report a 80-year-old female patient using pregabalin. Read More

    Premature ventricular contraction-induced concealed retrograde penetration: Electrocardiographic manifestations on anterograde ventricular preexcitation.
    Ann Noninvasive Electrocardiol 2017 Aug 24. Epub 2017 Aug 24.
    Division of Cardiology, Queen's University, Kingston, ON, Canada.
    In patients with manifest anterograde ventricular preexcitation, the electrocardiographic manifestation of the anomalous conduction through the simultaneous conduction over the atrioventricular (AV) node and the accessory pathway ("delta wave"); depends on several factors, the most representative being the conduction velocity over one or another connection. Occasionally, ventricular ectopic beats may present with retrograde penetration over one or both conduction pathways (AV node and/or accessory pathway), impacting on the morphology of the next immediate anterogradely conducted QRS. We present a case of a young patient with WPW syndrome and ectopic ventricular beats with different manifestations on the postectopic QRS due to concealed penetration of different conduction pathways. Read More

    Role of surface electrocardiogram precordial leads in localizing different anatomic sites of ectopic atrial tachycardia arising from lower right atrium in pediatric population.
    Ann Noninvasive Electrocardiol 2018 Jan 19;23(1). Epub 2017 Aug 19.
    Cardiology Department, Ain Shams University, Cairo, Egypt.
    Background: The study was designed to examine P wave morphology (PWM) in precordial leads (V-V) during ectopic atrial tachycardia (EAT) originating from low right atrium (RA) to identify the anatomic sites of these foci in children.

    Methods: Twenty-three consecutive pediatric patients (56% females, mean age 8.5 ± 2. Read More

    Supraventricular tachycardia, pregnancy, and water: A new insight in lifesaving treatment of rhythm disorders.
    Ann Noninvasive Electrocardiol 2017 Aug 19. Epub 2017 Aug 19.
    Cardiology Section, "S. Paolo" Hospital ASL BA, Bari, Italy.
    Pregnancy may predispose to paroxysmal supraventricular tachycardia (SVT), in subjects with or without identifiable heart disease. Many physiological conditions such as autonomic nervous system changes, altered systemic hemodynamics, etc. can contribute to the onset of arrhythmias during pregnancy. Read More

    Impact of functional training on geometric indices and fractal correlation property of heart rate variability in postmenopausal women.
    Ann Noninvasive Electrocardiol 2018 Jan 25;23(1). Epub 2017 Jul 25.
    ABC Medical School (FMABC), Santo André, São Paulo, Brazil.
    Background: To evaluate the influence of functional training on the geometric indices of heart rate variability (HRV) and fractal correlation properties of the dynamics of heart rate in menopausal women.

    Methods: Of 39 women who were in the period of menopause for more than a year and who did not practice any regular physical activity were divided into: Functional training group (FTG = 50 ± 4.5 years; 67. Read More

    The sensitivity of 38 heart rate variability measures to the addition of artifact in human and artificial 24-hr cardiac recordings.
    Ann Noninvasive Electrocardiol 2018 Jan 2;23(1). Epub 2017 Jul 2.
    School of Medicine Flinders University, Adelaide, SA, Australia.
    Background: Artifact is common in cardiac RR interval data derived from 24-hr recordings and has a significant impact on heart rate variability (HRV) measures. However, the relative impact of progressively added artifact on a large group of commonly used HRV measures has not been assessed. This study compared the relative sensitivity of 38 commonly used HRV measures to artifact to determine which measures show the most change with increasing increments of artifact. Read More

    Congenital Long QT syndrome and torsade de pointes.
    Ann Noninvasive Electrocardiol 2017 Nov 2;22(6). Epub 2017 Jul 2.
    Downstate Medical Center, State University of New York, Brooklyn, NY, USA.
    Since its initial description by Jervell and Lange-Nielsen in 1957, the congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. A prolonged QT interval in the surface electrocardiogram is the sine qua non of the LQTS and is a surrogate measure of the ventricular action potential duration (APD). Congenital as well as acquired alterations in certain cardiac ion channels can affect their currents in such a way as to increase the APD and hence the QT interval. Read More

    The association of QT interval components with atrial fibrillation.
    Ann Noninvasive Electrocardiol 2017 Jun 29. Epub 2017 Jun 29.
    Department of Internal Medicine, Section on Cardiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
    Background: Although abnormalities of the QT interval are associated with atrial fibrillation (AF), it is unclear whether ventricular depolarization (QRS duration) or repolarization (JT interval) is a more important marker of AF risk.

    Methods: This analysis included 4,181 (95% white; 59% women) participants from the Cardiovascular Health Study (CHS) who were free of baseline AF and major intraventricular delay. A linear scale was used to compute heart rate adjusted QT (QTa), QRS (QRS), and JT (JT) intervals. Read More

    A rare form of extremely wide QRS complex due to reversed homologous electrical ventricular separation of acute heart failure.
    Ann Noninvasive Electrocardiol 2018 Jan 29;23(1). Epub 2017 Jun 29.
    Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
    Electrical ventricular separation, as a special complete intraventricular block, denotes that ventricles be electrically separated into two or more parts caused by severe and wide damage of myocardium and conduction. Electrical ventricular separation can be divided into homologous and heterologous, homologous electrical ventricular separation is a rare phenomenon, literally the excitement of whole ventricle originate from supraventricle, on ECG, there are two different QRS waves which connect with an isoelectric line, one ST segment and T wave. We report a valve heart disease presented with complicated electrophysiological characteristics, which has reversed complex homologous electrical ventricular separation with second degree intraventricular block. Read More

    Ranolazine reduces repolarization heterogeneity in symptomatic patients with diabetes and non-flow-limiting coronary artery stenosis.
    Ann Noninvasive Electrocardiol 2018 Jan 27;23(1). Epub 2017 Jun 27.
    Beth Israel Deaconess Medical Center, Boston, MA, USA.
    Background: Experimental evidence suggests that ranolazine decreases susceptibility to ischemia-induced arrhythmias independent of effects on coronary artery blood flow.

    Objective: In symptomatic diabetic patients with non-flow-limiting coronary artery stenosis with diffuse atherosclerosis and/or microvascular dysfunction, we explored whether ranolazine reduces T-wave heterogeneity (TWH), an electrocardiographic (ECG) marker of arrhythmogenic repolarization abnormalities shown to predict sudden cardiac death.

    Methods: We studied all 16 patients with analyzable ECG recordings during rest and exercise tolerance testing before and after 4 weeks of ranolazine in the double-blind, crossover, placebo-controlled RAND-CFR trial (NCT01754259). Read More

    Bigeminal sandwiches galore.
    Ann Noninvasive Electrocardiol 2017 Jun 27. Epub 2017 Jun 27.
    Department of Clinical Sciences Lund, Clinical Physiology, Skane University Hospital, Lund University, Lund, Sweden.
    A long run of PVCs "sandwiched" in between the sinus beats resulting in an almost doubling of the heart rate-interpolated PVCs in bigeminy-is described. This case illustrates three interesting aspects of interpolated PVCs. Although they are not uncommon, long runs of interpolated PVCs in bigeminy are rare findings. Read More

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