454 results match your criteria Annals of General Psychiatry [Journal]
Ann Gen Psychiatry 2018 6;17:25. Epub 2018 Jun 6.
1Laboratory of Neuropsychiatric Genetics, Biomedical Sciences Research Group, School of Medicine, Universidad Antonio Nariño, Bogotá, 110231 Colombia.
Background: The study of health-related quality of life (HRQOL) is an important topic in mental health around the globe. However, there is the need for more evidence about the cumulative influence of psychological variables on HRQOL. The main aim of the study was to evaluate how specific personality traits might explain scores in HRQOL and to explore how this relationship might be mediated by coping styles and psychological distress. Read More
Ann Gen Psychiatry 2018 6;17:24. Epub 2018 Jun 6.
Department of Psychiatry, Chosun University Hospital, Chosun University, Gwangju, Republic of Korea.
Background: Neurosyphilis remains a diagnostic challenge in current psychiatric practice because of its pleomorphic psychiatric manifestations. Although neurosyphilis can present with a wide range of psychiatric symptoms, psychotic mania as its solitary manifestation is an unusual phenomenon.
Case Presentation: A 46-year-old man, with no history of any psychiatric disorder, exhibited abruptly developed symptoms of psychotic mania. Read More
Ann Gen Psychiatry 2018 1;17:22. Epub 2018 Jun 1.
2School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Crawley, WA Australia.
Background: Dopaminergic and opioid systems are involved in mediating drug reward and reinforcement of various types of substances including psychoactive compounds. Genes of both systems have been candidate for investigation for associations with substance use disorder (SUD) in various populations. This study is the first study to determine the allele frequency and the genetic association of the rs1076560 SNP and rs1799971 SNP variants in clinically diagnosed patients with SUD from the United Arab Emirates (UAE). Read More
Ann Gen Psychiatry 2018 11;17:20. Epub 2018 May 11.
Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, NJ USA.
Background: Despite the availability of effective antidepressants, about half of patients with major depressive disorder (MDD) display an inadequate response to their initial treatment. A large patient survey recently reported that 29.8% of MDD patients experiencing an inadequate treatment response felt frustrated about their medication and 19. Read More
Ann Gen Psychiatry 2018 11;17:19. Epub 2018 May 11.
Northcutt Consulting, LLC, Orlando, USA.
Background: Despite the current treatments available for panic disorder (PD), as many as one-third of patients have persistent and treatment-resistant panic attacks. Vortioxetine is an approved medicine for major depressive disorder and has been shown to have anxiolytic properties. The purpose of this study was to evaluate its efficacy and safety in an adult population with a diagnosis of PD. Read More
Ann Gen Psychiatry 2018 9;17:18. Epub 2018 May 9.
1Centre for Disability and Rehabilitation Studies, Department of Community Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Introduction: Postpartum depression is a mood disorder that affects approximately 10-15% of adult mothers yearly. This study sought to determine the prevalence of postpartum depression and interventions utilized for its management in a Health facility in Ghana.
Methods: A descriptive cross-sectional study design using a quantitative approach was used for the study. Read More
Ann Gen Psychiatry 2018 4;17:17. Epub 2018 May 4.
1Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy.
Background: Emergency services personnel face frequent exposure to potentially traumatic events, with the potential for chronic symptomatic distress. The DSM-5 recently recognized a particular risk for post-traumatic stress disorder (PTSD) among first responders (criterion A4) but data are still scarce on prevalence rates and correlates.
Objective: The aim of the present study was to explore the possible role of age, gender, and education training in a sample of emergency personnel diagnosed with DSM-5 PTSD. Read More
Ann Gen Psychiatry 2018 4;17:16. Epub 2018 May 4.
Research and Training Department, Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.
Background: People with severe mental disorders (SMDs) are associated with increased risk of infectious disease including human immunodeficiency virus infection (HIV) and hepatitis viruses, such as hepatitis B virus (HBV), hepatitis C virus (HCV), and other types of hepatitis viruses because of high-risk behaviors compared to the general population. The prevalence of HIV in people with SMDs is higher in females than in males. Unlike HIV, the prevalence of HBV and HCV is higher in males than in females. Read More
Ann Gen Psychiatry 2018 4;17:15. Epub 2018 May 4.
2Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.
Background: A number of risk factors for Internet addiction among adolescents have been identified to be associated with their behavior, familial, and parental factors. However, few studies have focused on the relationship between parental mental health and Internet addiction among adolescents. Therefore, we investigated the association between parental mental health and children's Internet addiction by controlling for several risk factors. Read More
Ann Gen Psychiatry 2018 18;17:14. Epub 2018 Apr 18.
AU-CNS, Association for the Application of Neuroscientific Knowledge to Social Aims, Pietrasanta, Lucca, Italy.
Background: Over-standard methadone doses are generally needed in the treatment of heroin use disorder (HUD) patients that display concomitant high-severity psychopathological symptomatology. A flexible dosing regimen may lead to higher retention rates in dual disorder (DD), as we demonstrated in bipolar 1 HUD patients, leading to outcomes that are as satisfactory as those of HUD patients without high-severity psychopathological symptomatology.
Objective: This study aimed to compare the long-term outcomes of treatment-resistant chronic psychosis HUD patients (PSY-HUD) with those of peers without dual disorder (HUD). Read More
Ann Gen Psychiatry 2018 13;17:13. Epub 2018 Mar 13.
Jordan Ministry of Health-Fuheis Psychiatric Hospital, Amman, Jordan.
Aim: This study aimed to detect if there were differences in compassion fatigue (CF) among nurses based on substance use and demographic variables of gender, marital status, type of health institution and income.
Background: Compassion fatigue is considered an outcome of poorly handled stressful situations in which nurses may respond with self-harming behaviours like substance use. Evidence in this area is critically lacking. Read More
Ann Gen Psychiatry 2018 2;17:11. Epub 2018 Mar 2.
1Department of Psychiatry, College of Health Sciences, University of Nairobi, P O Box 19676, Nairobi, 00202 Kenya.
Background: Psychiatric morbidity is commonly associated with HIV disease and may have adverse effects. This aspect may be overlooked at comprehensive HIV care centers in Low and Middle-Income Countries.
Objectives: The aim of this study was to determine the prevalence of undetected psychiatric morbidity among HIV/AIDS adult patients attending Comprehensive Care Centre in a semi-urban clinic, in Nairobi, Kenya. Read More
Ann Gen Psychiatry 2018 10;17. Epub 2018 Feb 10.
3Scientific Department, Ferrer, Barcelona, Spain.
Background: Agitation is a common feature of bipolar disorder and schizophrenia. Previous research indicates that specific symptoms impact caregiver burden in these conditions, but the impact of agitation on caregiver experience is poorly understood. The aim of this study was to characterise caregiver burden in providers of informal care for patients with bipolar disorder and schizophrenia who experience agitation. Read More
Ann Gen Psychiatry 2018 8;17. Epub 2018 Feb 8.
Medical Campus University of Oldenburg, School of Medicine and Health Sciences, Psychiatry and Psychotherapy-University Hospital, Karl-Jaspers-Klinik, Hermann-Ehlers-Straße 7, 26160 Bad Zwischenahn, Germany.
Background: Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology.
Methods: Using a prospective, observational design, we collected data from 982 hospitalized patients with a somatic illness for whom a psychiatric consultation was requested because of the presence of additional psychiatric symptoms. Read More
Ann Gen Psychiatry 2018 30;17. Epub 2018 Jan 30.
Department of Forensic Psychiatry, National Center Hospital of Neurology and Psychiatry, 4-1-1, Ogawahigashicho, Kodaira, Tokyo 187-8553 Japan.
Background: The Structured Assessment of PROtective Factors for violence risk (SAPROF) was recently developed as a strength-based addition to the risk assessment of future violent behavior. We examined the interrater reliability and predictive accuracy of the SAPROF for violence in forensic mental health inpatient units in Japan.
Methods: This retrospective record study provides an initial validation of the SAPROF in a Japanese sample of 95 forensic psychiatric inpatients from a complete 2008-2013 cohort. Read More
Ann Gen Psychiatry 2017 22;16:47. Epub 2017 Dec 22.
Department of Psychiatry, Huaian No. 3 People's Hospital, and Teaching Hospital of Xuzhou Medical University, No. 272 West Huaihai Road, Huai'an, Zip code: 223001 Jiangsu China.
Background: Differences in effectiveness and tolerability between different atypical antipsychotics may affect schizophrenic patients' treatment adherence or prognosis. However, which kind of antipsychotic was more effective and safe in the treatment of schizophrenia is still being debated. This study attempted to understand whether there are any differences in efficacy, acceptability, and safety between the five atypical antipsychotics in patients with first-episode schizophrenia. Read More
Ann Gen Psychiatry 2017 14;16:46. Epub 2017 Dec 14.
Department of Psychiatry, Chang-Gung Memorial Hospital at Linkuo, Taoyuan City, Taiwan.
Background: Clozapine-induced eosinophilia had been reported in several studies about blood dyscrasias in clozapine-treated patient. The largest study with 2404 patients in Italy found the incidence of 2.2% by criteria of more than 0. Read More
Ann Gen Psychiatry 2017 8;16:45. Epub 2017 Dec 8.
Department of Psychiatry, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, 222, Banpo-daero, Seocho-gu, Seoul, 06591 South Korea.
Background: Though Internet gaming disorder (IGD) is considered to share similar genetic vulnerability with substance addictions, little has been explored about the role of the genetic variants on IGD. This pilot study was designed to investigate the association of the polymorphism of the ankyrin repeat and kinase domain containing 1 () gene and and - of the dopamine D2 receptor () with IGD and their role on the personality and temperament traits in IGD among adult population.
Methods: Sixty-three subjects with IGD and 87 control subjects who regularly played Internet games were recruited. Read More
Ann Gen Psychiatry 2017 28;16:43. Epub 2017 Nov 28.
Department of Psychiatry, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokunishi, Shizuoka 4102211 Japan.
Objectives: Antipsychotics, even atypical ones, can induce hyperprolactinemia. Aripiprazole (APZ), a dopamine D2 partial agonist, has a unique pharmacological profile and few side effects. We investigated the incidence of hyperprolactinemia in patients with schizophrenia treated with APZ and other antipsychotics. Read More
Ann Gen Psychiatry 2017 22;16:42. Epub 2017 Nov 22.
Federation University Australia, Mount Helen, Ballarat, VIC Australia.
The severity of obsessive compulsive symptoms (OCS) is suggested to be normally distributed in the general population, and they appear to have an impact on a range of aspects of adolescent development. Importantly, there are individual differences regarding susceptibility to OCS. In the present repeated measures study, OCS were studied in relation to gender and emotional stability (as a personality trait) using a normative sample of 515 adolescents at ages 16 and 18 years. Read More
Ann Gen Psychiatry 2017 17;16:41. Epub 2017 Nov 17.
Laboratory of Molecular Biology, Department of Hematology, Military Hospital of Tunisia, Mont Fleury, 1008 Tunis, Tunisia.
Background: The angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D or indel) polymorphism has long been linked to Alzheimer's disease (AD), but the interpretation of established data remains controversial. The aim of this study was to determine whether the angiotensin-converting enzyme is associated with the risk of Alzheimer's disease in Tunisian patients.
Methods: We analyzed the genotype and allele frequency distribution of the ACE I/D gene polymorphism in 60 Tunisian AD patients and 120 healthy controls. Read More
Ann Gen Psychiatry 2017 16;16:40. Epub 2017 Nov 16.
Research and Training Department, Amanuel Mental Specialized Hospital, PO box: 1971, Addis Ababa, Ethiopia.
Background: About 25-60% of the homeless population is reported to have some form of mental disorder. To our knowledge, there are no studies aimed at the screening, diagnosis, treatment, care, rehabilitation, and support of homeless people with mental, neurologic, and substance use (MNS) disorders in general in Ethiopia. This is the first study of its kind in Africa which was aimed at screening, diagnosis, care, treatment, rehabilitation, and support of homeless individuals with possible MNS disorder. Read More
Ann Gen Psychiatry 2017 16;16:39. Epub 2017 Nov 16.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Hojatdost Street, Naderi Street, Keshavarz Blv., Tehran, Iran.
Background: Substantial evidence provides support for the role of diet in the prevention and control of mental disorders. However, since there is no study regarding the relationship between dietary diversity and stress or depression, we aimed to determine the relationship between the dietary diversity score (DDS) and stress and depression in women.
Methods: This descriptive-analytical cross-sectional study was performed on 360 women aged 20-49 years attending health centers in the south of Tehran. Read More
Ann Gen Psychiatry 2017 26;16:38. Epub 2017 Oct 26.
State Institution "Zaporizhzhia Medical Academy of Postgraduate Education Ministry of Health of Ukraine", 20 Winter boulevard, Zaporizhzhia, 69096 Ukraine.
Depression and cognitive dysfunction share a common neuropathological platform. Abnormal neural plasticity in the frontolimbic circuits has been linked to changes in the expression of neurotrophic factors, including IGF-1. These changes may result in clinical abnormalities observed over the course of major depressive disorder (MDD), including cognitive dysfunction. Read More
Ann Gen Psychiatry 2017 18;16:37. Epub 2017 Oct 18.
Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa Japan.
Background: Several studies have proven that the experiences of being bullied or bullying others are associated with poor mental health among adolescent youths. Our study aims to investigate the relationship between the experience of the bully/victim and mental health among preadolescents and adolescents.
Methods: Subjects were the Japanese fifth and sixth grade elementary school students (preadolescents: mean age = 11. Read More
Ann Gen Psychiatry 2017 17;16:36. Epub 2017 Oct 17.
Sunovion Pharmaceuticals Inc., Fort Lee, NJ USA.
Background: Severe and persistent mental illnesses, such as schizophrenia and bipolar disorder, are associated with increased risk of obesity compared to the general population. While the association of lurasidone and lower risk of weight gain has been established in short and longer-term clinical trial settings, information about lurasidone's association with weight gain in usual clinical care is limited. This analysis of usual clinical care evaluated weight changes associated with lurasidone treatment in patients with schizophrenia or bipolar disorder. Read More
Ann Gen Psychiatry 2017 16;16:35. Epub 2017 Oct 16.
Department of General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
Background: Our study aimed (1) to describe the proportion of psychological distress among Chinese outpatients at general hospitals, (2) to compare cognitive and behavioral characteristics of patients with different distress patterns, and (3) to investigate the discriminant function of the analyzed variables in indicating the affinity towards the different distress patterns.
Methods: This multicenter cross-sectional study was conducted at ten outpatient departments at Chinese general hospitals. The somatic symptom severity scale (PHQ-15), the nine-item depression scale (PHQ-9), and the seven-item anxiety scale (GAD-7) were employed to classify patients in terms of four distress patterns. Read More
Ann Gen Psychiatry 2017 25;16:34. Epub 2017 Sep 25.
Department of Biomedical Engineering, National Cheng Kung University, Tainan, 701 Taiwan.
Background: In this study, the international affective picture system was used to evoke emotion, and then the corresponding signals were collected. The features from different points of brainwaves, frequency, and entropy were used to identify normal, moderately, and markedly ill schizophrenic patients.
Methods: The signals were collected and preprocessed. Read More
Ann Gen Psychiatry 2017 15;16:33. Epub 2017 Sep 15.
Research Department, Chi-Mei Medical Center, 901 Chung Hwa Road, Yung Kung Dist., Tainan, 710 Taiwan.
Background: Workplace bullying is a prevalent problem in today's work places that has adverse effects on both bullying victims and organizations. To investigate the predictors of workplace bullying is an important task to prevent bullying victims of nurses in hospitals.
Objective: This study aims to explore the relationships among nurses' attitudes, negative perceptions, and negative acts regarding workplace bullying under the framework of the theory of planned behavior (TPB). Read More
Ann Gen Psychiatry 2017 6;16:32. Epub 2017 Sep 6.
SABIC Psychological Health Research & Applications Chair (SPHRAC), College of Medicine, King Saud University, PO Box 242069, Riyadh, 11322 Saudi Arabia.
Background: Psychological disorders including depression and anxiety are not rare in primary care clinics. The Patient Health Questionnaire (PHQ) is a clinical diagnostic tool that is widely utilized by primary health care physicians worldwide because it provides a practical in-clinic tool to screen for psychological disorders. This study evaluated the validity of the Arabic version of the PHQ in all six modules including depression, anxiety, somatic, panic, eating, and alcohol abuse disorders. Read More
Ann Gen Psychiatry 2017 9;16:31. Epub 2017 Aug 9.
Department of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Background: Major depressive episodes with psychotic features are more common in bipolar disorder than in major depressive disorder; however, there is little information on the optimal treatment for bipolar depression with psychotic features.
Case Presentation: The patient was a 69-year-old man. At the age of 66, he was admitted to the hospital for the treatment of bipolar depression with psychotic features. Read More
Ann Gen Psychiatry 2017 12;16:30. Epub 2017 Jul 12.
Psychiatry Department, Fattouma Bourguiba Hospital, 5000 Monastir, Tunisia.
Background: Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the relationship between NSS and cannabis use, an environmental risk factor of psychosis.
Methods: This was a cross-sectional study in consecutively admitted patients hospitalized for first-episode psychosis. Read More
Ann Gen Psychiatry 2017 11;16:29. Epub 2017 Jul 11.
Psychiatry Department, College of Medicine and Health Science, Bahir Dar University, P.O. Box: 79, Bahir Dar, Ethiopia.
Introduction: The World Health Organization (WHO) clearly states the importance of psychological well-being in the definition of health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity". However, in the community, the lives of people with bipolar disorders are often harsh and abusive. Till now, the rate and related information concerning verbal or physical abuse among patients with bipolar disorder at psychiatric outpatient clinics have not been well addressed in Ethiopian settings. Read More
Ann Gen Psychiatry 2017 6;16:28. Epub 2017 Jul 6.
2nd Psychiatry Department, Attikon University Hospital, National and Kapodistrian University of Athens - Medical School, 1 Rimini Street, 12462 Athens, Greece.
Islam is the dominant religion in about 56 countries around the globe, and has more than 1.2 billion followers. Islam represents a holistic way of life, and according to a large proportion of its followers, the Islamic law or Shari'ah should prevail over secular law and should be implemented as state law. Read More
Ann Gen Psychiatry 2017 3;16:26. Epub 2017 Jul 3.
Research Department, Chi-Mei Medical Center, 901 Chung Hwa Road, Yung Kung Dist., Tainan, 710 Taiwan.
Background: Workplace bullying has been measured in many studies to investigate mental health issues. None uses online computerized adaptive testing (CAT) with cutting points to report bully prevalence at workplace.
Objective: To develop an online CAT to examine person being bullied and verify whether item response theory-based CAT can be applied online for nurses to measure exposure to workplace bullying. Read More
Ann Gen Psychiatry 2017 14;16:25. Epub 2017 Jun 14.
Bali Psychiatric Center, No. 33, Huafushan, Bali Dist., New Taipei City, 24936 Taiwan.
Background: The effects of antipsychotic drug withdrawal have been inadequately studied. Case reports have described dyskinesia occurring in patients with several antipsychotics withdrawn, but studies on amisulpride withdrawal dyskinesia are lacking.
Case Presentation: A 63-year-old man, who was diagnosed with schizophrenia at age 49, received amisulpride treatment since age 62. Read More
Ann Gen Psychiatry 2017 30;16:24. Epub 2017 May 30.
Psychiatry Department, Faculty of Medicine and Pharmacy, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Background: Lhermitte-Duclos disease (LDD) is a rare cerebellar lesion characterized by a hamartomatous lesion in the posterior fossa. Mainly diagnosed by MRI, the clinical presentation is usually made of neurological symptoms.
Case Presentation: We present here a rare case of a woman who developed depressive symptoms that inaugurated the clinical presentation of LDD. Read More
Ann Gen Psychiatry 2017 28;16:23. Epub 2017 Apr 28.
Department of Psychiatry, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul, 08308 South Korea.
Background: Gambling disorder (GD) is defined as persistent and recurrent problematic gambling behavior leading to clinically significant impairment or distress. The prevalence of GD has been shown to be 1.2-7. Read More
Ann Gen Psychiatry 2017 4;16:19. Epub 2017 Apr 4.
Laboratory of Inherited Metabolic Diseases, Centre de Biologie Est, Hospices Civils de Lyon, Bron, France.
Background: Wilson's disease (WD) is a rare autosomal-recessive, inherited disorder caused by a mutation in the copper-transporting gene affecting the liver and nervous system. About 30% of patients with WD may initially present with psychiatric symptoms, and diagnosis can be difficult to establish. The objectives of the present preliminary study were  to evaluate the relevance of serum copper (Cu) and ceruloplasmin (Cp) measures in hospitalized patients with psychiatric disorders; and  to identify possible mutations in the gene in patients with abnormal biological copper profile. Read More