836 results match your criteria Annals of Gastroenterology & Hepatology [Journal]


Authors' reply.

Ann Gastroenterol 2019 Jan-Feb;32(1):112. Epub 2018 Dec 7.

Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Emmanuel Ofori, Madhavi Reddy, Douglas G. Adler), USA.

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http://dx.doi.org/10.20524/aog.2018.0334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302186PMC
December 2018
1 Read

Maggots at colostomy site: an unusual finding!

Ann Gastroenterol 2019 Jan-Feb;32(1):111. Epub 2018 Sep 24.

Department of General Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

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http://dx.doi.org/10.20524/aog.2018.0312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302203PMC
September 2018
2 Reads

Rectal mucosa-associated lymphoid tissue lymphoma treated by endoscopic submucosal resection with band ligation.

Ann Gastroenterol 2019 Jan-Feb;32(1):110. Epub 2018 Nov 2.

Department of Gastroenterology, National Hospital Organization Fukuyama Medical Center, Fukuyama, Japan.

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http://dx.doi.org/10.20524/aog.2018.0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302188PMC
November 2018
2 Reads

Kappa light-chain amyloidosis of gastrointestinal tract.

Ann Gastroenterol 2019 Jan-Feb;32(1):109. Epub 2018 Oct 3.

Department of Gastroenterology, Sendai Kousei Hospital, Japan.

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302194PMC
October 2018
6 Reads

Burkitt's lymphoma masquerading as a Crohn's flare.

Ann Gastroenterol 2019 Jan-Feb;32(1):107-108. Epub 2018 Dec 5.

Division of Gastroenterology (Jason D. Ferreira), Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, USA.

Sporadic Burkitt's lymphoma can have a variety of clinical manifestations, including a constellation of gastrointestinal symptoms that can masquerade as other conditions and lead to a delay in diagnosis. Here we review a case of Burkitt's lymphoma in a patient with a history of Crohn's disease, initially thought to be a Crohn's flare on initial presentation. This case highlights the importance of keeping a broad differential and ruling out Crohn's mimics in the process of treating a presumed exacerbation of inflammatory bowel disease. Read More

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http://dx.doi.org/10.20524/aog.2018.0332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302193PMC
December 2018
1 Read

Ten-year survival outcomes of patients with potentially resectable gastric cancer: impact of clinicopathologic and treatment-related risk factors.

Ann Gastroenterol 2019 Jan-Feb;32(1):99-106. Epub 2018 Oct 3.

Third Department of Surgery (Sylvia Krivan, Nikolaos Machairas, Dimitrios Schizas, George Martikos, Evangelos P. Misiakos, Pavlos Patapis, Theodoros Liakakos).

Background: Despite therapeutic advancements, gastric cancer (GC) remains a leading cause of death worldwide.

Methods: This retrospective cohort study statistically analyzed the clinicopathologic characteristics, treatments and outcomes of patients with potentially resectable GC managed at our institution between 2006 and 2010. The STROBE checklist was applied. Read More

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http://dx.doi.org/10.20524/aog.2018.0320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302201PMC
October 2018
2 Reads

Sofosbuvir in combination with ribavirin or simeprevir: real-life study of patients with hepatitis C genotype 4.

Ann Gastroenterol 2019 Jan-Feb;32(1):93-98. Epub 2018 Nov 24.

Division of Biochemistry, Faculty of Science (Mohamed Abdel-Gabbar, Mohamed Ramadan).

Background: The discovery of direct-acting antiviral agents (DAA) is an outstanding achievement of modern medicine in the current century. The current study aimed to explore the effectiveness and safety of two regimens sofosbuvir (SOF) in combination with either ribavirin (RBV) or simeprevir (SMV) in chronic hepatitis C (CHC) genotype (GT) 4 patients in Egypt.

Methods: A total of 201 patients, treatment-naïve and experienced, with CHC GT4 infection were allocated into two groups based on the type of the regimen used. Read More

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http://dx.doi.org/10.20524/aog.2018.0327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302204PMC
November 2018
1 Read

Intergenotypic 2k/1b hepatitis C virus recombinants in the East Macedonia and Thrace region of Greece.

Ann Gastroenterol 2019 Jan-Feb;32(1):88-92. Epub 2018 Nov 2.

Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis (Katerina Kassela, Eleni Kokkiou, Fani Souvalidou, Panayotis Mimidis, Penelope Mavromara).

Background: Intergenotypic recombinant hepatitis C virus (HCV) strains emerge rarely during coinfection of the same individual with two HCV genotypes. Few recombinant HCV strains have been identified to date and only one, CRF01 2k/1b, has become a worldwide concern. This study reevaluated the genotyping of three HCV genotype 2 strains from a group of patients with an unusually low rate of sustained virological response after pegylated interferon/ribavirin treatment. Read More

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http://dx.doi.org/10.20524/aog.2018.0322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302191PMC
November 2018
1 Read

Polymerase chain reaction for detection of mucosal cytomegalovirus infection in patients with acute ulcerative colitis.

Ann Gastroenterol 2019 Jan-Feb;32(1):81-87. Epub 2018 Oct 3.

Gastroenterology Department, Sheffield Teaching Hospital NHS Foundation Trust, United Kingdom.

Background: Cytomegalovirus (CMV) infection is associated with acute exacerbations of ulcerative colitis (UC) but its clinical relevance remains uncertain. The primary aim of this study was to assess the prevalence of CMV infection in UC patients using viral polymerase chain reaction (PCR) analysis of mucosal biopsy samples. Secondary aims were to establish whether the disease was due to a primary infection or reactivation and to note associated risk factors and clinical outcomes. Read More

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http://dx.doi.org/10.20524/aog.2018.0318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302192PMC
October 2018
2 Reads

Impact of bariatric surgery on outcomes of patients with celiac disease: a nationwide inpatient sample analysis, 2004-2014.

Ann Gastroenterol 2019 Jan-Feb;32(1):73-80. Epub 2018 Nov 2.

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT (Basile Njei), USA.

Background: While patients with celiac disease have increasingly developed an atypical pattern of weight gain and obesity, the role of bariatric surgery remains unclear. The primary aim of this study was to evaluate the effect of bariatric surgery on clinical outcomes among hospitalized patients with celiac disease.

Methods: The United States Nationwide Inpatient Sample database was queried for discharges with co-diagnoses of morbid obesity and celiac disease between 2004 and 2014. Read More

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http://dx.doi.org/10.20524/aog.2018.0323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302198PMC
November 2018
1 Read

The incidence of neoplasia in patients with autoimmune metaplastic atrophic gastritis: a renewed call for surveillance.

Ann Gastroenterol 2019 Jan-Feb;32(1):67-72. Epub 2018 Nov 8.

Division of Gastroenterology (Nadim Mahmud, Bryson W. Katona, David C. Metz).

Background: Autoimmune metaplastic atrophic gastritis (AMAG) is an immune-mediated process that may lead to pernicious anemia (PA) and an increased risk of gastric cancer. Although some literature supports 3- or 5-year endoscopic surveillance for gastric cancer in patients with PA, no formal guidance exists for the general AMAG population. We sought to identify the prevalence and incidence rates of dysplasia or adenocarcinoma in patients with AMAG in order to clarify endoscopic best practices. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302190PMC
November 2018
10 Reads

Adapted first-line treatment of infection in Algerian children.

Ann Gastroenterol 2019 Jan-Feb;32(1):60-66. Epub 2018 Oct 3.

Department of Gastroenterology, Queen Fabiola Children's Hospital, Free University of Brussels, Belgium (Zhor Guechi).

Background: () infection is acquired in early life and continues to have a high prevalence, especially in developing countries. Growing antibiotic-resistant strains necessitate adapted treatments. This study aimed to compare the efficacy, side effects, and influence of resistance of strains between two different treatments. Read More

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http://dx.doi.org/10.20524/aog.2018.0317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302196PMC
October 2018
2 Reads

Improvement in the implementation of management guidelines among primary care physicians following a targeted educational intervention.

Ann Gastroenterol 2019 Jan-Feb;32(1):52-59. Epub 2018 Nov 24.

Tel Aviv and Central Administration, Clalit Health Services, Tel Aviv (Shlomo Birkenfeld), Israel.

Background: Consensus guidelines recommend that in regions with a high rate of clarithromycin resistance, () infection be treated with 4 drugs. Compliance with this recommendation among primary care physicians (PCPs) is low. We aimed to examine whether PCP compliance with treatment recommendations increased following a targeted educational intervention. Read More

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http://dx.doi.org/10.20524/aog.2018.0329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302200PMC
November 2018
2 Reads

Long-term outcome of myotomy and fundoplication based on intraoperative real-time high-resolution manometry in achalasia patients.

Ann Gastroenterol 2019 Jan-Feb;32(1):46-51. Epub 2018 Nov 14.

Department of Surgery, 1 Propaedeutic Surgical Clinic, Hippocration General Hospital of Athens, University of Athens (Tania Triantafyllou, Charalampos Theodoropoulos, Georgia Georgiou, Vasileios Kalles, Konstantinos Filis, Georgios Zografos, Dimitrios Theodorou).

Background: Current treatment options for achalasia of the esophagus predominantly consist of endoscopic myotomy or laparoscopic myotomy combined with a partial fundoplication. The intraoperative use of conventional manometry has previously been proposed with various results. The aim of the present study was to introduce the use of high-resolution manometry (HRM) during surgical treatment for achalasia and to assess the long-term outcome of this technique. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302195PMC
November 2018
3 Reads

Endoscopic ultrasound-guided ablation of pancreatic cystic neoplasms: ready for prime time?

Ann Gastroenterol 2019 Jan-Feb;32(1):39-45. Epub 2018 Dec 3.

Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Douglas G. Adler), USA.

With the increase in the use of cross-sectional diagnostic imaging, there has been a concomitant rise in the rate of detected pancreatic cystic lesions. Recent years have seen the rise of newly developed therapeutic modalities to treat pancreatic lesions via ablation. Specifically, through the use of endoscopic ultrasound-guided therapy, endoscopists can potentially ablate these lesions safely and with minimally invasive techniques. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302202PMC
December 2018
2 Reads

Fecal microbiota transplantation: donor relation, fresh or frozen, delivery methods, cost-effectiveness.

Ann Gastroenterol 2019 Jan-Feb;32(1):30-38. Epub 2018 Nov 17.

Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Academic Affiliate of The Icahn School of Medicine at Mount Sinai, Clinical Affiliate of The Mount Sinai Hospital, Brooklyn (Andrew Ofosu, Emmanuel Ofori, Madhavi Reddy), New York, USA.

Fecal microbiota transplantation (FMT) has evolved into a robust and efficient means for treating recurrent infection (CDI). Our narrative review looks at the donor selection, preparation, delivery techniques and cost-effectiveness of FMT. We searched electronic databases, including PubMed, MEDLINE, Google Scholar, and Cochrane Databases, for studies that compared the biological effects of donor selection, fresh or frozen fecal preparation, and various delivery techniques. Read More

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http://dx.doi.org/10.20524/aog.2018.0328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302197PMC
November 2018
1 Read

Endoscopic management of tracheoesophageal fistulas.

Ann Gastroenterol 2019 Jan-Feb;32(1):24-29. Epub 2018 Oct 29.

Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Huntsman Cancer Center, Salt Lake City, Utah (Emmanuel Ofori, Madhavi Reddy, Douglas G. Adler), USA.

Tracheoesophageal fistulas (TEF) are pathologic communications between the trachea and esophagus. TEF can lead to significant respiratory distress that may result in lethal respiratory compromise, often due to recurrent and intractable infections. Through the use of endoscopy, some TEF can be successfully repaired using different approaches depending on the size, location, availability, and experience of the treating endoscopist. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302189PMC
October 2018
7 Reads

Hellenic Association for the Study of the Liver Clinical Practice Guidelines: Autoimmune hepatitis.

Ann Gastroenterol 2019 Jan-Feb;32(1):1-23. Epub 2018 Nov 29.

Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, "Laiko" General Hospital of Athens, Athens (George V. Papatheodoridis), Greece.

Autoimmune hepatitis (AIH) is a relatively rare acute or chronic liver disease of unknown etiology characterized by large heterogeneity. Its distribution is global, covering all ages, both sexes and all ethnic groups. The aim of the present Clinical Practice Guidelines (CPG) of the Hellenic Association for the Study of the Liver was to provide updated guidance and help to gastroenterologists, hepatologists, internists and general practitioners for AIH diagnosis and management. Read More

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http://dx.doi.org/10.20524/aog.2018.0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302199PMC
November 2018
1 Read

Unusual polypoid mass lesion in the rectum.

Ann Gastroenterol 2018 Nov-Dec;31(6):752. Epub 2018 Sep 14.

Surgery (Rajesh Gupta), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.20524/aog.2018.0308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191860PMC
September 2018
1 Read

Hip orthopedic material presenting as an unusual rectal foreign body.

Ann Gastroenterol 2018 Nov-Dec;31(6):751. Epub 2018 Aug 6.

Department of Gastroenterology and Digestive Endoscopy, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France.

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191863PMC
August 2018
2 Reads

Refractory bleeding due to duodenal varices.

Ann Gastroenterol 2018 Nov-Dec;31(6):750. Epub 2018 Sep 14.

Department of Radiology (Arya Bagherpour), The University of Texas Medical Branch, USA.

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http://dx.doi.org/10.20524/aog.2018.0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191872PMC
September 2018
1 Read

Medical hypothesis: speculating on the pathogenesis of acute diverticulitis.

Authors:
Angelo Zullo

Ann Gastroenterol 2018 Nov-Dec;31(6):747-749. Epub 2018 Sep 26.

Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy.

The pathogenetic process of acute diverticulitis remains speculative. According to the most widely accepted theory, the mechanism involved is "traumatic" damage to the mucosa due to fecolith impaction, as occurs in large diverticula. However, not uncommonly, diverticulitis develops in young patients with only few and small diverticula, where fecolith trapping is very unlikely. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191870PMC
September 2018
3 Reads

Comparing endoscopic ultrasound-guided core biopsies of solid pancreatic and extrapancreatic lesions: a large single-operator experience with a new fine-needle biopsy needle.

Ann Gastroenterol 2018 Nov-Dec;31(6):742-746. Epub 2018 Sep 24.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah, USA.

Background: There has been a paradigm shift in tertiary centers from endoscopic ultrasound (EUS) fine-needle aspiration to EUS fine-needle biopsy (EUS-FNB) for tissue acquisition in solid lesions. While data exists on the use of FNB needles in solid pancreatic lesions, very few studies looked at the utility of FNB in solid extrapancreatic lesions. Our aim was to study and compare the technical success and feasibility of EUS-FNB in evaluating solid pancreatic and extrapancreatic lesions using a novel FNB needle. Read More

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http://dx.doi.org/10.20524/aog.2018.0313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191864PMC
September 2018
1 Read

Endoscopic ultrasound-guided transmural drainage by cautery-tipped lumen-apposing metal stent: exploring the possible indications.

Ann Gastroenterol 2018 Nov-Dec;31(6):735-741. Epub 2018 Jul 26.

Digestive Endoscopy Unit, Department of Gastroenterology, Humanitas Research Hospital, Milan (Andrea Anderloni, Milena Di Leo, Silvia Carrara, Alessandro Fugazza, Roberta Maselli, Francesco Auriemma, Alessandro Repici).

Background: The recently introduced Hot AXIOS™ system for endoscopic ultrasound (EUS)-guided transenteric drainage has the potential to change interventional endoscopy significantly. The aim of our study was to assess the effectiveness and safety of this new type of lumen-apposing metal stent (LAMS) with cautery system for pancreatic collection, and gallbladder and biliary tree drainage.

Methods: We retrospectively reviewed consecutive patients undergoing EUS-guided drainage by LAMS with cautery system in a tertiary-care academic medical center between March 2014 and March 2017. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191873PMC
July 2018
5 Reads

Management of anastomotic biliary stricture after liver transplantation: metal versus plastic stent.

Ann Gastroenterol 2018 Nov-Dec;31(6):728-734. Epub 2018 Jul 20.

Gastroenterology Unit, Department of Medical Sciences, University of Foggia, Italy (Antonio Facciorusso; Nicola Muscatiello).

Background: Post-transplant anastomotic biliary strictures remain refractory to endoscopic therapy in a considerable number of cases. The aim of this meta-analysis was to compare fully-covered self-expandable metal and plastic stents in the management of post-transplant biliary strictures.

Methods: A meta-analysis was performed using a random effects model; results were expressed as odds ratio (OR) and mean standardized difference. Read More

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http://dx.doi.org/10.20524/aog.2018.0297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191877PMC
July 2018
1 Read

Liver transplantation for hepatocellular carcinoma with live donors or extended criteria donors: a propensity score-matched comparison.

Ann Gastroenterol 2018 Nov-Dec;31(6):722-727. Epub 2018 Jul 27.

Department of Mathematics and Technology, Koblenz University of Applied Science, Remagen, Germany (Markus Neuhäuser).

Background: To compare patient survival after liver transplantation (LT) for hepatocellular carcinoma (HCC) from live donors (LD) or extended criteria donors (ECD).

Methods: Data from consecutive LT procedures for HCC involving either LD or ECD were reviewed. Patient survival was our primary outcome. Read More

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http://dx.doi.org/10.20524/aog.2018.0301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191876PMC
July 2018
11 Reads

A genotype-specific baseline score predicts post-treatment response to peginterferon alfa-2a in hepatitis B e antigen-negative chronic hepatitis B.

Ann Gastroenterol 2018 Nov-Dec;31(6):712-721. Epub 2018 Jul 26.

Department of Gastroenterology, Medical School of National & Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece (George V. Papatheodoridis).

Background: Peginterferon alfa-2a induces durable responses in some hepatitis B e antigen-negative patients, but robust pretreatment predictors are not available to identify likely responders. In this study we aimed to develop genotype-specific baseline scoring systems to predict response.

Methods: Data from 323 hepatitis B e antigen-negative peginterferon alfa-2a recipients from three studies were analyzed. Read More

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http://dx.doi.org/10.20524/aog.2018.0300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191871PMC
July 2018
2 Reads

Interleukin-17A and B-cell activating factor in chronic hepatitis C patients with or without asymptomatic mixed cryoglobulinemia: effects of antiviral treatment and correlations with vitamin D.

Ann Gastroenterol 2018 Nov-Dec;31(6):705-711. Epub 2018 Sep 14.

2nd Department of Internal Medicine and Research Laboratory, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.

Background: Several studies have provided conflicting results regarding the immune responses in chronic hepatitis C (CHC) patients with mixed cryoglobulinemia (MC). The importance of B-cell activating factor (BAFF) in MC has been described, but the role of interleukin (IL)-17A is less clear.

Methods: Serum concentrations of IL-17A, BAFF and 25-OH vitamin D were measured in CHC patients at baseline, end of treatment, and 6 months post-treatment with pegylated interferon-α and ribavirin, versus 12 healthy controls. Read More

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http://www.annalsgastro.gr/index.php/annalsgastro/article/do
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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
Publisher Site
http://dx.doi.org/10.20524/aog.2018.0310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191865PMC
September 2018
5 Reads

Panitumumab in combination with modified docetaxel/cisplatin/5-fluorouracil as first-line treatment in gastric and gastroesophageal junction adenocarcinomas: a multicenter phase II study by the Hellenic Oncology Research Group.

Ann Gastroenterol 2018 Nov-Dec;31(6):698-704. Epub 2018 Sep 14.

Hellenic Oncology Research Group, Athens, Greece.

Background: A phase I/II study to define the maximum tolerated dose (MTD) of biweekly docetaxel/cisplatin/5-fluorouracil (DCF) plus panitumumab (P), its efficacy, and tolerability as first-line treatment in advanced gastroesophageal cancer.

Methods: In phase I part, patients with unresectable locally advanced or metastatic adenocarcinomas of the stomach or the gastroesophageal junction received cisplatin (40 mg/m on day 1), leucovorin (400 mg/m on day 1), 5-fluorouracil (400 mg/m bolus on day 1), 5-fluorouracil (1000 mg/m/daycontinuous infusion on days 1-2), and escalated doses of docetaxel (on day 1) plus P (6 mg/kg on day 1) every 2 weeks. In phase II part, patients were treated with DCF/P at the MTD and the primary endpoint was response rate. Read More

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http://dx.doi.org/10.20524/aog.2018.0311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191861PMC
September 2018
3 Reads

Small bowel bleeding in patients with left ventricular assist device: outcomes of conservative therapy versus balloon-assisted enteroscopy.

Ann Gastroenterol 2018 Nov-Dec;31(6):692-697. Epub 2018 Sep 26.

Division of Gastroenterology and Hepatology (Badr Al-Bawardy, Emmanuel Gorospe, Louis M. Wong Kee Song, Jeffrey A. Alexander, David H. Bruining, Nayantara Coelho-Prabhu, Elizabeth Rajan).

Background: Small bowel bleeding (SBB) accounts for 30% of gastrointestinal bleeding (GIB) episodes in patients with a left ventricular assist device (LVAD). The aim of this study was to determine the outcomes of conservative therapy (CT) compared to balloon-assisted enteroscopy (BAE) in the management of SBB in LVAD patients.

Methods: A retrospective review was performed of a prospectively maintained LVAD database from January 2003 to July 2015. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191869PMC
September 2018
12 Reads

Efficacy of bio-optimized extracts of turmeric and essential fennel oil on the quality of life in patients with irritable bowel syndrome.

Ann Gastroenterol 2018 Nov-Dec;31(6):685-691. Epub 2018 Aug 6.

Biostatistics, University Hospital of Liège, Belgium (Nathalie Maes, Adelin Albert).

Background: The use of herbal products to treat irritable bowel syndrome (IBS), a disease that frequently affects the quality of life (QoL), is still under evaluation. This open pilot study assessed the efficacy of bio-optimized extracts of turmeric and essential fennel oil (Enterofytol®) in IBS patients.

Methods: A total of 211 patients (14% diarrhea-predominant, IBS-D; 24% constipation-predominant, IBS-C; 62% mixed, IBS-M) were enrolled by general practitioners and completed questionnaires measuring symptom severity and QoL before and after Enterofytol®, two capsules b. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191874PMC
August 2018
14 Reads

High-frequency miniprobe endoscopic ultrasonography for evaluation of indeterminate esophageal strictures.

Ann Gastroenterol 2018 Nov-Dec;31(6):680-684. Epub 2018 Sep 14.

Department of Surgery (Rajesh Gupta), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Patients with esophageal stricture who have normal mucosa and whose endoscopic biopsies are inconclusive pose a difficult diagnostic dilemma. We prospectively assessed high-frequency miniprobe endoscopic ultrasonography (EUS) for the evaluation of indeterminate esophageal strictures.

Methods: Over a period of 3 years, 19 patients (14 male; mean age: 58. Read More

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http://dx.doi.org/10.20524/aog.2018.0307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191862PMC
September 2018
3 Reads

Impact of direct-acting antiviral agents on the development of hepatocellular carcinoma: evidence and pathophysiological issues.

Ann Gastroenterol 2018 Nov-Dec;31(6):670-679. Epub 2018 Sep 14.

Academic Department of Medicine, Medical School, National and Kapodistrian University of Athens, "Hippokration" General Hospital (Maria Tampaki, John Koskinas), Athens, Greece.

Hepatitis C virus (HCV) infection is currently one of the main causes of cirrhosis and hepatocellular carcinoma (HCC) at a global level. Recently, a new generation of direct-acting antiviral agents (DAAs) has entered the HCV treatment landscape, providing impressively high rates of sustained virological response (SVR), and is expected to lead to an eventual decrease in HCV-related cirrhosis, liver transplantation and mortality. However, during the first years of their use, several studies reported a possible correlation between DAA treatment and an increased risk of HCC. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191866PMC
September 2018
2 Reads

Malignant peritoneal mesothelioma: clinical aspects, and therapeutic perspectives.

Ann Gastroenterol 2018 Nov-Dec;31(6):659-669. Epub 2018 Sep 14.

Department of Gastroenterology, University Hospital of Ioannina, Faculty of Medicine, School of Health Sciences, University of Ioannina, Greece (Konstantinos H. Katsanos, Dimitrios K. Christodoulou).

Malignant peritoneal mesothelioma (MPM) is a rare disease with a wide clinical spectrum. It arises from the peritoneal lining and commonly presents with diffuse, extensive spread throughout the abdomen and, more rarely, metastatic spread beyond the abdominal cavity. Computed tomography, magnetic resonance imaging and positron-emission tomography are important diagnostic tools used for the preoperative staging of MPM. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191875PMC
September 2018
9 Reads

Alcohol and narcotics use in inflammatory bowel disease.

Ann Gastroenterol 2018 Nov-Dec;31(6):649-658. Epub 2018 Aug 1.

Department of Gastroenterology, University of Ioannina, Medical School (George Mantzouranis, Eleftheria Fafliora, Athina Tatsioni, George Glantzounis, Konstantinos H. Katsanos, Dimitrios K. Christodoulou), Greece.

The aim of this study was to evaluate alcohol consumption and narcotics use among patients with inflammatory bowel diseases (IBD). A comprehensive literature search was conducted in Medline using relevant keywords. The references of the retrieved articles were also searched to identify additional articles. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191867PMC
August 2018
16 Reads

Gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome: common overlapping gastrointestinal disorders.

Ann Gastroenterol 2018 Nov-Dec;31(6):639-648. Epub 2018 Sep 26.

Gastroenterology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa (Nicola de Bortoli, Giulia Sgherri, Eleonora Albano, Linda Ceccarelli, Massimo Bellini, Santino Marchi), Caserta, Italy.

Several studies have indicated an overlap between gastroesophageal reflux disease (GERD) and various functional gastrointestinal disorders (FGIDs). The overlapping conditions reported have mainly been functional dyspepsia (FD) and irritable bowel syndrome (IBS). The available literature is frequently based on symptomatic questionnaires or endoscopic procedures to diagnose GERD. Read More

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http://dx.doi.org/10.20524/aog.2018.0314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191868PMC
September 2018
14 Reads

Endoscopic ultrasonography of the upper gastrointestinal tract: take a look at the pancreas!

Ann Gastroenterol 2018 Sep-Oct;31(5):637. Epub 2018 Jun 19.

Department of Gastroenterology and Hepatology, Molinette Hospital, Turin (Claudio De Angelis), Italy.

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http://dx.doi.org/10.20524/aog.2018.0285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102461PMC
June 2018
9 Reads

Authors' reply.

Ann Gastroenterol 2018 Sep-Oct;31(5):637-638. Epub 2018 Jun 19.

Endoscopy Unit, Digestive Service, Alicante University General Hospital, Isabial-Fisabio, Alicante (Juan F. Martínez, José R. Aparicio), Spain.

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http://dx.doi.org/10.20524/aog.2018.0286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102451PMC
June 2018
2 Reads

Utility of endoscopic ultrasound in hemorrhage from recurrent duodenal varices.

Ann Gastroenterol 2018 Sep-Oct;31(5):636. Epub 2018 Jul 12.

Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.

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http://dx.doi.org/10.20524/aog.2018.0289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102457PMC
July 2018
12 Reads

"Posterior-like" anterior peroral endoscopic myotomy: a novel concept.

Ann Gastroenterol 2018 Sep-Oct;31(5):635. Epub 2018 Jul 20.

Department of Gastroenterology, Mediterraneo Hospital, Athens, Greece.

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http://dx.doi.org/10.20524/aog.2018.0298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102452PMC
July 2018
3 Reads

Submucosal tunneling endoscopic septum division of a Zenker's diverticulum.

Ann Gastroenterol 2018 Sep-Oct;31(5):634. Epub 2018 Jul 20.

Department of Internal Medicine (Ekaterini Mastronikola), Metropolitan Hospital, Neo Faliro, Piraeus, Greece.

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http://dx.doi.org/10.20524/aog.2018.0296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102454PMC
July 2018
1 Read

Post-fundoplication high-resolution esophageal manometry in a patient with Ehlers-Danlos syndrome.

Ann Gastroenterol 2018 Sep-Oct;31(5):633. Epub 2018 Jul 19.

Baylor College of Medicine (Vignesh Ramachandran, Kevin P. Shah, Douglas S. Fishman, Eric H. Chiou), Houston, Texas, USA.

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http://dx.doi.org/10.20524/aog.2018.0294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102467PMC
July 2018
2 Reads

The utility of early cross-sectional imaging to evaluate suspected acute mild pancreatitis.

Ann Gastroenterol 2018 Sep-Oct;31(5):628-632. Epub 2018 Jul 13.

Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine (Paul T. Reynolds, Evan K. Brady, Saurabh Chawla), Atlanta, GA, USA.

Background: There are roughly 300,000 hospitalizations for acute pancreatitis annually in the United States. Many of the affected patients at our institution undergo computed tomography (CT) or magnetic resonance imaging (MRI) unnecessarily early during their admissions. We hypothesize that cross-sectional imaging within 48 h of admission in patients meeting the criteria for acute, mild pancreatitis is over-utilized and does not change management. Read More

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http://dx.doi.org/10.20524/aog.2018.0291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102458PMC
July 2018
3 Reads

Postoperative morbidity in elderly patients after gastric cancer surgery.

Ann Gastroenterol 2018 Sep-Oct;31(5):621-627. Epub 2018 May 9.

Department of Surgery, Yodogawa Christian Hospital, Osaka, Japan.

Background: Elderly patients have a high risk of adverse outcomes after surgery. Therefore, it is essential to determine the predictive factors for postoperative morbidity in elderly patients undergoing gastric cancer surgery.

Methods: A total of 544 patients who underwent elective gastrectomy for gastric cancer at Yodogawa Christian Hospital between January 2007 and December 2015 were divided into the elderly group (age ≥70 years, n=282) and a control group (age <70 years, n=262). Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102466PMC
May 2018
17 Reads

Everolimus with or without mycophenolate mofetil in a liver transplantation setting: a single-center experience.

Ann Gastroenterol 2018 Sep-Oct;31(5):613-620. Epub 2018 May 25.

4 Department of Internal Medicine, Medical School of Aristotle University, Hippokration General Hospital of Thessaloniki (Evangelos Cholongitas, Ioannis Goulis, Aliki Angelaki, Evangelos Akriviadis), Greece.

Background: This study evaluated the efficacy, safety, and impact on renal function of everolimus in patients after liver transplantation (LT) with or without mycophenolate mofetil (MMF).

Methods: We evaluated LT recipients with calcineurin inhibitor (CNI)-related renal dysfunction after everolimus initiation. Laboratory data, including evaluation of renal function based on glomerular filtration rate (GFR) at baseline (i. Read More

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http://dx.doi.org/10.20524/aog.2018.0278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102469PMC
May 2018
2 Reads

Presepsin levels in cirrhotic patients with bacterial infections and/or portal hypertension-related bleeding, presenting with or without acute kidney injury.

Ann Gastroenterol 2018 Sep-Oct;31(5):604-612. Epub 2018 Jul 18.

Academic Department of Internal Medicine, Hepatogastroenterology Unit, "Agioi Anargyroi" General and Oncology Hospital of Kifisia, National and Kapodistrian University of Athens, Greece, The study was partially supported by an unrestricted research grant from AbbVie Pharmaceuticals S.A. The authors state that AbbVie Pharmaceuticals S.A. had no involvement in the study design, collection, analysis, interpretation of data, writing of the report or the decision to submit the manuscript for publication.

Background: Bacterial infections in cirrhotic patients remain a challenge. Presepsin has been proposed as a valuable sepsis biomarker. We aimed to assess plasma presepsin levels in uncomplicated cirrhotic patients and to correlate them with liver disease severity and complicating events, defined as documented bacterial infection with or without concomitant portal hypertension-related bleeding, or bleeding without documented bacterial infection, with or without acute kidney injury. Read More

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http://www.annalsgastro.gr/files/journals/1/earlyview/2018/e
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http://dx.doi.org/10.20524/aog.2018.0292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102455PMC
July 2018
11 Reads

Clinical and epidemiological characteristics of hepatitis C virus-infected people who inject drugs: a Greek descriptive analysis.

Ann Gastroenterol 2018 Sep-Oct;31(5):598-603. Epub 2018 Jul 19.

2 Academic Department of Internal Medicine, Hippokration General Hospital, Athens (Hariklia Kranidioti, Pinelopi Antonakaki, Olga Anagnostou, Melanie Deutsch, Spilios Manolakopoulos), Greece.

Background: It is estimated that 17,000 people who inject drugs (PWID) in Greece have hepatitis C virus (HCV) viremia. The aim of our study was to explore the characteristics of the HCV-infected, direct acting antiviral (DAA)-naïve PWID.

Methods: This is a retrospective analysis of PWID with HCV infection. Read More

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http://dx.doi.org/10.20524/aog.2018.0293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102460PMC
July 2018
3 Reads

Relationship between antibodies to hepatitis C virus core+1 protein and treatment outcome.

Ann Gastroenterol 2018 Sep-Oct;31(5):593-597. Epub 2018 Jul 13.

First Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis (Theodora Mylopoulou, Konstantinos Mimidis), Greece.

Background: It has been suggested that hepatitis C virus (HCV) core+1 protein plays a crucial role in the viral life cycle, potentially affecting liver cirrhosis and the development of hepatocellular carcinoma.

Methods: To investigate its relationship with the outcome of HCV standard combination therapy with peginterferon-α plus ribavirin, we screened 139 consecutive HCV patients (119 with chronic HCV infection and 20 who spontaneously cleared HCV) for the presence of anti-core+1 antibodies (Abs). In addition, liver fibrosis was determined by FibroScan in all but one patients. Read More

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http://dx.doi.org/10.20524/aog.2018.0290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102464PMC
July 2018
1 Read

A multicenter, prospective, observational study of the long-term outcomes of Crohn's disease patients under routine care management in Greece.

Ann Gastroenterol 2018 Sep-Oct;31(5):583-592. Epub 2018 Jul 20.

Gastroenterology Department, "Tzaneio" General Hospital of Piraeus, Piraeus (Charalambos Tzathas), Greece.

Background: Real-world data on management patterns and long-term outcomes of patients with inadequately controlled Crohn's disease (CD) in Greece are scarce.

Methods: This was a multicenter, prospective observational study of 18-65-year-old CD patients whose physicians judged that their current therapy was inadequate to control their condition and therefore decided to switch treatment. Data were collected at enrollment (time of switch), and 30, 54 and 104 weeks post-enrollment. Read More

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http://dx.doi.org/10.20524/aog.2018.0295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102459PMC
July 2018
1 Read