668 results match your criteria Annals of Clinical Microbiology and Antimicrobials[Journal]


Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes.

Ann Clin Microbiol Antimicrob 2020 May 23;19(1):21. Epub 2020 May 23.

UCL-TB & UCL Respiratory, Division of Medicine, University College London, London, UK.

The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions between COVID-19 and tuberculosis (TB), which still ranks as the leading cause of death from a single infectious disease globally. Read More

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http://dx.doi.org/10.1186/s12941-020-00363-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245173PMC

New ST623 of Cryptococcus neoformans isolated from a patient with non-Hodgkin's lymphoma in the Brazilian Amazon.

Ann Clin Microbiol Antimicrob 2020 May 20;19(1):20. Epub 2020 May 20.

Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas-HEMOAM, Manaus, AM, Brazil.

Background: Cryptococcosis is a disease of wide geographic distribution. It is most critical when it affects immunocompromised patients, with AIDS, tuberculosis or other diseases that require prolonged hospitalization.

Methods: This study described a case report, molecular epidemiology, the phylogenetic relationship, along with antifungal susceptibility test of a new ST 623 of C. Read More

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http://dx.doi.org/10.1186/s12941-020-00361-3DOI Listing

Venezuelan equine encephalitis virus: the problem is not over for tropical America.

Ann Clin Microbiol Antimicrob 2020 May 19;19(1):19. Epub 2020 May 19.

Instituto de Investigaciones Biológicas del Trópico (IIBT), Facultad de Medicina Veterinaria y Zootecnia, Universidad de Córdoba, Montería, Córdoba, Colombia.

The equine encephalitis viruses, Venezuelan (VEEV), East (EEEV) and West (WEEV), belong to the genus alphavirus, family Togaviridae and still represent a threat for human and animal public health in the Americas. In both, these infections are characterized by high viremia, rash, fever, encephalitis and death. VEEV encephalitis is similar, clinically, to other arboviral diseases, such as dengue, Zika or chikungunya. Read More

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http://dx.doi.org/10.1186/s12941-020-00360-4DOI Listing

Plasma CRP level is positively associated with the severity of COVID-19.

Ann Clin Microbiol Antimicrob 2020 May 15;19(1):18. Epub 2020 May 15.

Department of Laboratory Medicine, The Second Affiliated Hospital of Wenzhou Medical University, Yuying Children's Hospital, No. 109 Western Xueyuan Road, Wenzhou, 325000, China.

Aims: The coronavirus disease 2019 (COVID-19) is characterized as highly contagious and deadly; however there is no credible and convenient biomarker to predict the severity of the disease. The aim of the present study was to estimate whether the CRP level is able to act as a marker in indicating the severity of COVID-19.

Methods: Patients who complained cough or chest pain with or without fever were enrolled after laboratory confirmed of SARS-CoV-2 viral nucleic acid via qRT-PCR. Read More

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http://dx.doi.org/10.1186/s12941-020-00362-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227180PMC

Characterisation of antibiotic resistance, virulence, clonality and mortality in MRSA and MSSA bloodstream infections at a tertiary-level hospital in Hungary: a 6-year retrospective study.

Ann Clin Microbiol Antimicrob 2020 May 7;19(1):17. Epub 2020 May 7.

Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary.

Background: Staphylococcus aureus bloodstream infections (BSI) cause significant morbidity and mortality due to the frequent antibiotic resistance, toxin and adhesin production of the bacterium. These characteristics differ significantly in methicillin resistant (MRSA) and methicillin sensitive S. aureus (MSSA) and also among isolates of different MRSA clones, contributing to the outcome of S. Read More

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http://dx.doi.org/10.1186/s12941-020-00357-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206755PMC

Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin.

Ann Clin Microbiol Antimicrob 2020 Apr 24;19(1):16. Epub 2020 Apr 24.

Asociación Colombiana de Infectología, Bogotá DC, Colombia.

Background: COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents are being used, including chloroquine. We report here the clinical features and therapeutic course of the first reported patient with confirmed COVID-19 pneumonia that recovered in Colombia, after the use of chloroquine and clarithromycin. Read More

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http://dx.doi.org/10.1186/s12941-020-00358-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180682PMC

Microbiota composition and distribution along the female reproductive tract of women with endometriosis.

Ann Clin Microbiol Antimicrob 2020 Apr 16;19(1):15. Epub 2020 Apr 16.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Endometriosis (EMS) is a multifactorial disease that affects 10%-15% women of reproductive age and is associated with chronic pelvic pain and infertility. The pathogenesis of EMS has not been consistently explained until now. In this study, we involved 36 endometriosis patients and 14 control subjects who performed laparoscopic surgery due to gynecological benign tumor. Read More

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http://dx.doi.org/10.1186/s12941-020-00356-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161132PMC

In vitro activity of ceftazidime-avibactam and comparators against Gram-negative bacterial isolates collected in the Asia-Pacific region as part of the INFORM program (2015-2017).

Ann Clin Microbiol Antimicrob 2020 Apr 1;19(1):14. Epub 2020 Apr 1.

Pfizer Inc., 558 Eastern Point Rd, Groton, CT, 06340, USA.

Background: Antimicrobial resistance among nosocomial Gram-negative pathogens is a cause for concern in the Asia-Pacific region. The aims of this study were to measure the rates of resistance among clinical isolates collected in Asia-Pacific countries, and to determine the in vitro antimicrobial activities of ceftazidime-avibactam and comparators against these isolates.

Methods: CLSI broth microdilution methodology was used to determine antimicrobial activity and EUCAST breakpoints version 9. Read More

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http://dx.doi.org/10.1186/s12941-020-00355-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110689PMC

The risk of vancomycin toxicity in patients with liver impairment.

Ann Clin Microbiol Antimicrob 2020 Mar 31;19(1):13. Epub 2020 Mar 31.

Department of Pharmacy Administration, Chung-Ang University College of Pharmacy, Seoul, South Korea.

Background: The influence of liver disease on the pharmacokinetic profile, the risk of acute kidney injury, and excessive drug exposure in patients treated with vancomycin was examined.

Methods: A retrospective cohort study was performed with patients discharged from a medical center between January 2011 and June 2018 who received vancomycin therapy. Patients were stratified according to liver dysfunction (no to mild liver dysfunction (NMLD) and moderate to severe liver dysfunction (MSLD) based on the Child-Pugh score. Read More

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http://dx.doi.org/10.1186/s12941-020-00354-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110653PMC

The emergence of the hypervirulent Klebsiella pneumoniae (hvKp) strains among circulating clonal complex 147 (CC147) harbouring bla carbapenemases in a tertiary care center of Iran.

Ann Clin Microbiol Antimicrob 2020 Mar 31;19(1):12. Epub 2020 Mar 31.

Microbiology Department, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.

Background: Klebsiella pneumoniae is a public health concern because of its ability to develop multidrug resistance and hypervirulent genotypes, of those capsular types K1 and K2 cause community and nosocomial life-threatening infections. This study aimed to determine the antibiotic susceptibility patterns and genotypic traits of a collection of Klebsiella spp. isolates. Read More

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http://dx.doi.org/10.1186/s12941-020-00349-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110786PMC
March 2020
1.514 Impact Factor

Comparison of fungal and bacterial keratitis between tropical and subtropical Taiwan: a prospective cohort study.

Ann Clin Microbiol Antimicrob 2020 Mar 30;19(1):11. Epub 2020 Mar 30.

Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung City, Taiwan.

Background: Fungal keratitis (FK) has been shown to be a climate-sensitive disease. The differentiation between FK from bacterial keratitis (BK) was difficult. The purpose of this study was to compare the bacteriology and mycology between tropical and subtropical Taiwan and to investigate the independent risk factors for identification of fungi from bacteria. Read More

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http://dx.doi.org/10.1186/s12941-020-00353-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104486PMC

Investigation of biofilm production and its association with genetic and phenotypic characteristics of OM (osteomyelitis) and non-OM orthopedic Staphylococcus aureus.

Ann Clin Microbiol Antimicrob 2020 Mar 26;19(1):10. Epub 2020 Mar 26.

Department of Orthopedics, Southwest Hospital, Army Medical University, Gaotanyan Main Street 30#, District Shapingba, Chongqing, China.

Background: Staphylococcus aureus is a primary pathogen of orthopedic infections. By mediating antimicrobial resistance, S. aureus biofilm plays an important role in the recalcitrance of orthopedic infections, especially for the intractable osteomyelitis (OM). Read More

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http://dx.doi.org/10.1186/s12941-020-00352-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099788PMC

Ceftobiprole: a potential empirical post-operative monotherapy in prosthetic joint infections.

Ann Clin Microbiol Antimicrob 2020 Mar 21;19(1). Epub 2020 Mar 21.

Institute of Microbiology, Lille University Hospital, 59037, Lille, France.

Background: This study aimed to evaluate in vitro susceptibility to ceftobiprole of clinical strains identified from prosthetic joint infections (PJIs) compared to that of the associations currently recommended for post-operative empirical antibiotic therapy (PEAT) (vancomycin with either cefepime, third-generation cephalosporin or piperacillin-tazobactam).

Methods: We performed a 1-year retrospective study on all the surgical procedures performed in our hospital for PJI. Susceptibility profiles of all the strains cultured from surgical samples were reviewed to compare ceftobiprole to current used associations. Read More

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http://dx.doi.org/10.1186/s12941-020-00351-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085185PMC

A rapid and simple method for routine determination of antibiotic sensitivity to biofilm populations of Pseudomonas aeruginosa.

Ann Clin Microbiol Antimicrob 2020 Mar 13;19(1). Epub 2020 Mar 13.

Department of Microbiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Treatment of infections by Pseudomonas aeruginosa forming biofilms after antimicrobial testing on planktonic bacteria can result in substantial failure. Therefore, we offer a robust and simple experimental platform to test the impact of antimicrobials on biofilms. Antibiotic response patterns varied uniquely within biofilm formation capacity and minimal biofilm eradication concentrations (MBECs) has a significantly better discriminatory power than minimum inhibitory concentrations (MICs) to differentiate the overall efficiency of antibiotics to eradicate biofilm. Read More

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http://dx.doi.org/10.1186/s12941-020-00350-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071750PMC

Antimicrobial utilization and antimicrobial resistance in patients with haematological malignancies in Japan: a multi-centre cross-sectional study.

Ann Clin Microbiol Antimicrob 2020 Feb 17;19(1). Epub 2020 Feb 17.

Department of Public Health and Epidemiology, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan.

Background: Infection is a major complication for patients with haematological malignancies. It is important to better understand the use of antimicrobial agents and antibiotic resistance for appropriate treatment and prevention of drug resistance. However, very few multi-centre analyses have focused on the use of antimicrobial agents and antibiotic resistance have been carried out in Japan. Read More

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http://dx.doi.org/10.1186/s12941-020-00348-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027235PMC
February 2020

Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review.

Ann Clin Microbiol Antimicrob 2020 Jan 28;19(1). Epub 2020 Jan 28.

Department of Human Genetics, Guru Nanak Dev University, Amritsar, 143005, India.

Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and clinical problem but also include large social and psychological consequences. Understanding the mechanisms of both commensalism and pathogenesis are necessary for the development of efficient diagnosis and treatment strategies for these enigmatic vaginal infections. Through this review, an attempt has been made to analyze vaginal microbiota (VMB) from scratch and to provide an update on its current understanding in relation to health and common RVVI i. Read More

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http://dx.doi.org/10.1186/s12941-020-0347-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986042PMC
January 2020
1.514 Impact Factor

Pharmacokinetics of plasma lopinavir and ritonavir in tuberculosis-HIV co-infected African adult patients also receiving rifabutin 150 or 300 mg three times per week.

Ann Clin Microbiol Antimicrob 2020 Jan 22;19(1). Epub 2020 Jan 22.

Biomedical Research Laboratory, Institut de Recherche en Sciences de la Santé (IRSS), 03BP7192, Ouagadougou, Burkina Faso.

Background: To evaluate the pharmacokinetic of plasma lopinavir (LPV) and ritonavir (RTV) when co-administered with three times weekly (TPW) rifabutin (RBT) at a dose of either 150 or 300 mg in African tuberculosis (TB) and HIV co-infected adult patients.

Methods: This is a pharmacokinetic study conducted in Ouagadougou among patients treated with a standard dosage of LPV/RTV 400/100 mg twice daily and RBT 150 mg TPW (arm A = 9 patients) or rifabutin 300 mg TPW (arm B = 7 patients) based regimens. Patients were recruited from the Bogodogo and Kossodo district hospitals in Ouagadougou from May 2013 to December 2015. Read More

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http://dx.doi.org/10.1186/s12941-020-0345-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974970PMC
January 2020
1.514 Impact Factor

The challenging management of Rift Valley Fever in humans: literature review of the clinical disease and algorithm proposal.

Ann Clin Microbiol Antimicrob 2020 Jan 22;19(1). Epub 2020 Jan 22.

Laveran Military Teaching Hospital, CS500413384, Marseille Cedex 13, France.

Rift Valley Fever (RVF) is an emerging zoonotic arbovirus with a complex cycle of transmission that makes difficult the prediction of its expansion. Recent outbreaks outside Africa have led to rediscover the human disease but it remains poorly known. The wide spectrum of acute and delayed manifestations with potential unfavorable outcome much complicate the management of suspected cases and prediction of morbidity and mortality during an outbreak. Read More

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http://dx.doi.org/10.1186/s12941-020-0346-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977312PMC
January 2020

Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan.

Ann Clin Microbiol Antimicrob 2020 Jan 15;19(1). Epub 2020 Jan 15.

The Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, and Umea Centre for Microbial Research, Umea University, Umeå, Sweden.

Background: Acinetobacter baumannii is a Gram-negative opportunistic pathogen with a notorious reputation of being resistant to antimicrobial agents. The capability of A. baumannii to persist and disseminate between healthcare settings has raised a major concern worldwide. Read More

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http://dx.doi.org/10.1186/s12941-019-0344-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964048PMC
January 2020
1.514 Impact Factor

Klebsiella pneumoniae: an increasing threat to public health.

Ann Clin Microbiol Antimicrob 2020 Jan 9;19(1). Epub 2020 Jan 9.

College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.

Objectives: This review fills the paucity of information on K. pneumoniae as a nosocomial pathogen by providing pooled data on epidemiological risk factors, resistant trends and profiles and resistant and virulent genes of this organism in Asia.

Methods: Exhaustive search was conducted using PubMed, Web of Science, and Google scholar for most studies addressing the prevalence, risk factors, drug resistant-mediated genes and/or virulent factors of K. Read More

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http://dx.doi.org/10.1186/s12941-019-0343-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050612PMC
January 2020
1.514 Impact Factor

Evolving trends in infective endocarditis in a developing country: a consequence of medical progress?

Ann Clin Microbiol Antimicrob 2019 Dec 17;18(1):43. Epub 2019 Dec 17.

Department of Medicine, University Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.

Background: Staphylococcus has replaced streptococcus as the most common cause of infective endocarditis (IE) in developed health care systems. The trend in developing countries is less clear.

Aim: To examine the epidemiological trends of infective endocarditis in a developing nation. Read More

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http://dx.doi.org/10.1186/s12941-019-0341-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918620PMC
December 2019

Extended spectrum β-lactamase producing uropathogenic Escherichia coli and the correlation of biofilm with antibiotics resistance in Nepal.

Ann Clin Microbiol Antimicrob 2019 Dec 17;18(1):42. Epub 2019 Dec 17.

Department of Biotechnology, National College, Tribhuvan University, Naya Bazar, Kathmandu, Nepal.

Background: Urinary tract infection (UTI) is one of the frequently diagnosed infectious diseases which is caused mainly by Escherichia coli. E. coli confers resistance against the two major classes of antibiotics due to the production of extended spectrum β-lactamase enzymes (ESBL), biofilm, etc. Read More

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http://dx.doi.org/10.1186/s12941-019-0340-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918583PMC
December 2019

Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients.

Ann Clin Microbiol Antimicrob 2019 Dec 12;18(1):40. Epub 2019 Dec 12.

Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Background: Colistin resistance is mainly driven by alterations in the Gram-negative outer membrane lipopolysaccharides and is caused, in most cases, by mutations in mgrB gene. However, the recent emergence of plasmid-encoded colistin resistance among Enterobacteriaceae strains represents a serious threat to global public health. In this paper we have investigated the rates of colistin resistance and the underlying mechanisms in 450 Klebsiella pneumoniae and Escherichia coli isolates obtained from cancer patients in Egypt. Read More

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http://dx.doi.org/10.1186/s12941-019-0339-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909591PMC
December 2019
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Molecular detection and antibiotic resistance pattern of extended-spectrum beta-lactamase producing Escherichia coli in a Tertiary Hospital in Enugu, Nigeria.

Ann Clin Microbiol Antimicrob 2019 Dec 12;18(1):41. Epub 2019 Dec 12.

Department of Medical Microbiology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu State, Nigeria.

Background: The use of antibiotic agents in the treatment of infectious diseases has greatly contributed to the decrease in morbidity and mortality, but these great advances in treatment are being undermined by the rapidly increasing antimicrobial resistant organisms. Extended-spectrum beta-lactamases are enzymes hydrolyzing the beta lactam antibiotics, including third generation cephalosporins and monobactams but not cephamycins and carbapenems. They pose a serious global health threat and have become a challenge for health care providers. Read More

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http://dx.doi.org/10.1186/s12941-019-0342-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909585PMC
December 2019

Multiplex ligation reaction based on probe melting curve analysis: a pragmatic approach for the identification of 30 common Salmonella serovars.

Ann Clin Microbiol Antimicrob 2019 Dec 5;18(1):39. Epub 2019 Dec 5.

Shenzhen Center for Disease Control and Prevention, 8 Longyuan Road, Nanshan District, Shenzhen, China.

Background: While Salmonella serotyping is of paramount importance for the disease intervention of salmonellosis, a fast and easy-to-operate molecular serotyping solution remains elusive. We have developed a multiplex ligation reaction based on probe melting curve analysis (MLMA) for the identification of 30 common Salmonella serovars.

Methods: Serovar-specific primers and probes were designed based on a comparison of gene targets (wzx and wzy encoding for somatic antigen biosynthesis; fliC and fljB for flagellar antigens) from 5868 Salmonella genomes. Read More

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http://dx.doi.org/10.1186/s12941-019-0338-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894471PMC
December 2019

Potential factors contributing to the poor antimicrobial efficacy of SAAP-148 in a rat wound infection model.

Ann Clin Microbiol Antimicrob 2019 Dec 3;18(1):38. Epub 2019 Dec 3.

Association of Dutch Burn Centres, Zeestraat 29, 1941 AJ, Beverwijk, The Netherlands.

Background: We investigated the efficacy of a synthetic antimicrobial peptide SAAP-148, which was shown to be effective against Methicillin-resistant Staphylococcus aureus (MRSA) on tape-stripped mice skin. Unexpectedly, SAAP-148 was not effective against MRSA in our pilot study using rats with excision wounds. Therefore, we investigated factors that might have contributed to the poor efficacy of SAAP-148. Read More

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http://dx.doi.org/10.1186/s12941-019-0336-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891976PMC
December 2019
1.514 Impact Factor

Determination of antimicrobial susceptibility and biofilm production in Staphylococcus aureus isolated from white coats of health university students.

Ann Clin Microbiol Antimicrob 2019 Nov 28;18(1):37. Epub 2019 Nov 28.

Universidade do Oeste Paulista - UNOESTE, Rua José Bongiovani, 700 - Cidade Universitária, Presidente Prudente, SP, CEP 19050-920, Brazil.

This study aimed at detecting Staphylococcus aureus from white coats of college students and characterizing antimicrobial susceptibility and biofilm production. Bacterial samples (n = 300) were obtained from white coats of 100 college students from August 2015 to March 2017 S. aureus was isolated and it´s resistance profile was assessed by antimicrobial disk-diffusion technique, screening for methicillin-resistant Staphylococcus aureus (MRSA), detection of mecA gene by PCR, and determination of staphylococcal cassette chromosome mec (SCCmec) by multiplex PCR. Read More

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http://dx.doi.org/10.1186/s12941-019-0337-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883624PMC
November 2019

Systematic review of carbapenem-resistant Enterobacteriaceae causing neonatal sepsis in China.

Ann Clin Microbiol Antimicrob 2019 Nov 14;18(1):36. Epub 2019 Nov 14.

Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St. George's University of London, London, UK.

Background: Carbapenems are β-lactam antibiotics which are used to treat severe infections caused by multidrug resistant Enterobacteriacea. The recent emergence and rapid spread of Enterobacteriaceae resistant to carbapenems is a global concern. We undertook a systematic review of the antibiotic susceptibility and genotypic characteristics of carbapenem-resistant Enterobacteriaceae in Chinese neonates. Read More

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http://dx.doi.org/10.1186/s12941-019-0334-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857301PMC
November 2019

Effect of camera monitoring and feedback along with training on hospital infection rate in a neonatal intensive care unit.

Ann Clin Microbiol Antimicrob 2019 Nov 13;18(1):35. Epub 2019 Nov 13.

Member of Infection Control Committee, Sakarya University Faculty of Medicine, Adnan Menderes Bulvari, Sakarya, Turkey.

Background: In terms of pediatric healthcare-associated infections (HAI), neonatal intensive care units (NICU) constitute the greatest risk. Contacting a health care personnel, either directly or indirectly, elevates NICU occurrence rate and risks other infants in the same unit. In this study, it is aimed to retrospectively analyze the effect of the training along with camera monitoring and feedback (CMAF) to control the infection following a small outbreak. Read More

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http://dx.doi.org/10.1186/s12941-019-0332-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852772PMC
November 2019

A 7-year surveillance of the drug resistance in Klebsiella pneumoniae from a primary health care center.

Ann Clin Microbiol Antimicrob 2019 Nov 9;18(1):34. Epub 2019 Nov 9.

Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, No. 60 Wuningxi Road, Dongyang, Zhejiang, China.

Background: The increased prevalence of Klebsiella pneumoniae infections and resistance rates are a current cause for concern. However, data for resistance rates in K. pneumoniae strains from primary hospitals and the resistance distribution among the different isolate sample sources are scarce. Read More

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http://dx.doi.org/10.1186/s12941-019-0335-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842199PMC
November 2019
1 Read

Doxycycline-encapsulated solid lipid nanoparticles for the enhanced antibacterial potential to treat the chronic brucellosis and preventing its relapse: in vivo study.

Ann Clin Microbiol Antimicrob 2019 Nov 9;18(1):33. Epub 2019 Nov 9.

Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Brucellosis is one of the most important infection of diseases. Due to its large period of treatment and survival ability of bacteria inside the macrophages, relapse of this disease is the main challenge, especially, after the treatment.

Objective: The current study was carried out to evaluate the antibacterial effect of solid lipid nanoparticles loaded with doxycycline on the Brucella melitensis in in vivo conditions. Read More

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http://dx.doi.org/10.1186/s12941-019-0333-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842259PMC
November 2019
1.514 Impact Factor

Exploring the phenotype and genotype of multi-drug resistant Klebsiella pneumoniae harbouring bla group extended-spectrum β-lactamases recovered from paediatric clinical cases in Shenzhen, China.

Ann Clin Microbiol Antimicrob 2019 Nov 5;18(1):32. Epub 2019 Nov 5.

Department of Haematology and Oncology, Shenzhen Children's Hospital, 7019 Yitian Road, District Futian, Shenzhen, 518038, Guangdong Province, China.

Background: Emergence and spread of β-lactamase resistant Klebsiella pneumoniae have posed a serious threat, especially in paediatric patients globally. The present study focuses on explore drug resistance profile and molecular characterization of carbapenemase and extended-spectrum β-lactamase producing K. pneumoniae isolated from paediatric patients in Shenzhen, China. Read More

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http://dx.doi.org/10.1186/s12941-019-0331-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829983PMC
November 2019

The effect of concomitant fibromyalgia in HIV infected patients receiving antiretroviral therapy: a prospective cross-sectional study.

Ann Clin Microbiol Antimicrob 2019 Oct 31;18(1):31. Epub 2019 Oct 31.

Department of Clinical Microbiology and Infectious Diseases, Ataturk Training and Research Hospital, Faculty of Medicine, Izmir Katip Celebi University, Basın Sitesi, 35360, Karabaglar/Izmir, Turkey.

Background: HIV infected patients receiving antiretroviral therapy (ART) have extensive musculoskeletal system involvement. Arthralgia and myalgia are the most common forms. Fibromyalgia Syndrome (FMS) is a chronic pain syndrome of the musculoskeletal system characterized by diffuse pain including arthralgia and myalgia. Read More

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http://dx.doi.org/10.1186/s12941-019-0330-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824054PMC
October 2019
1 Read

DALBACEN cohort: dalbavancin as consolidation therapy in patients with endocarditis and/or bloodstream infection produced by gram-positive cocci.

Ann Clin Microbiol Antimicrob 2019 Oct 19;18(1):30. Epub 2019 Oct 19.

Department of Infectious Diseases, Hospital Universitario Virgen de las Nieves, Av. de las Fuerzas Armadas no 2, 18014, Granada, Spain.

Objectives: To analyse the effectiveness of dalbavancin (DBV) in clinical practice as consolidation therapy in patients with bloodstream infection (BSI) and/or infective endocarditis (IE) produced by gram-positive cocci (GPC), as well as its safety and pharmacoeconomic impact.

Methods: A multicentre, observational and retrospective study was conducted of hospitalised patients with IE and/or BSI produced by GPC who received at least one dose of DBV. Clinical response was assessed during hospitalization, at 3 months and at 1 year. Read More

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http://dx.doi.org/10.1186/s12941-019-0329-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800500PMC
October 2019

Evaluation of serological test of Zika in an endemic area of flavivirus in the Colombian Caribbean.

Ann Clin Microbiol Antimicrob 2019 Oct 14;18(1):29. Epub 2019 Oct 14.

Instituto de Investigaciones Biológicas del Trópico, Universidad de Córdoba, Montería, Córdoba, Colombia.

The Zika virus (ZIKV) is an emerging flavivirus transmitted primarily through arthropods, endemic in Africa, Asia, and the Americas, and is considered a global threat by the World Health Organization.

Objective: To evaluate a commercial Zika virus test (IgG/IgM catalog number B815C, Biocan, Canada.

Methods: We evaluated 30 sera of patients diagnosed with Dengue, Leptospira, Malaria, Hantavirus, and Chikungunya. Read More

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http://dx.doi.org/10.1186/s12941-019-0328-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792200PMC
October 2019
1 Read

Determining the clinical significance of co-colonization of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in the intestinal tracts of patients in intensive care units: a case-control study.

Ann Clin Microbiol Antimicrob 2019 Oct 10;18(1):28. Epub 2019 Oct 10.

Division of Infectious Diseases, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Inchon-ro 73, Seongbuk-gu, Seoul, 02841, Republic of Korea.

Background: The emergence of vancomycin-resistant Staphylococcus aureus (VRSA) has become a global concern for public health. The proximity of vancomycin-resistant enterococcus (VRE) and methicillin-resistant S. aureus (MRSA) is considered to be one of the foremost risk factors for the development of VRSA. Read More

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http://dx.doi.org/10.1186/s12941-019-0327-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785887PMC
October 2019
1.514 Impact Factor

Health care providers' perceptions regarding antimicrobial stewardship programs (AMS) implementation-facilitators and challenges: a cross-sectional study in the Eastern province of Saudi Arabia.

Ann Clin Microbiol Antimicrob 2019 Sep 24;18(1):26. Epub 2019 Sep 24.

Pharmacy Services Department, King Fahd Hospital of the University (KFHU), Imam Abdulrahman Bin Faisal University (University of Dammam), Dammam, Saudi Arabia.

Background: Infections result from invasions of an organism into body tissues leading to diseases and complications that might eventually lead to death. Inappropriate use of antimicrobials has led to development of antimicrobial resistance (AMR) which has been associated with increased mortality, morbidity and health costs. Antimicrobial stewardship (AMS) programs are designed to ensure appropriate selections of an effective antimicrobial drugs and optimizing antibiotic use to minimize antibiotic resistance by implementing certain policies, strategies and guidelines. Read More

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http://dx.doi.org/10.1186/s12941-019-0325-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760054PMC
September 2019

Detection and molecular characterization of urinary tract HIV-1 populations.

Ann Clin Microbiol Antimicrob 2019 Sep 24;18(1):27. Epub 2019 Sep 24.

Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases, Johannesburg, South Africa.

Background: Identification of all possible HIV reservoirs is an important aspect in HIV eradication efforts. The urinary tract has however not been well studied as a potential HIV reservoir. In this pilot study we molecularly characterized HIV-1 viruses in urine and plasma samples to investigate HIV-1 replication, compartmentalization and persistence in the urinary tract. Read More

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http://dx.doi.org/10.1186/s12941-019-0326-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760049PMC
September 2019
1 Read

Nasal colonization of methicillin resistant Staphylococcus aureus in Ethiopia: a systematic review and meta-analysis.

Ann Clin Microbiol Antimicrob 2019 Sep 5;18(1):25. Epub 2019 Sep 5.

Department of Medical Laboratory Science, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is one of a medically important Gram-positive bacteria, which can be harboured majorly in the nasal cavity. Risk of consequent infection in a person colonized with S. aureus as well as MRSA upsurges with time and remains insistently increased. Read More

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http://dx.doi.org/10.1186/s12941-019-0324-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727550PMC
September 2019

A systematic review of the impact of antifungal stewardship interventions in the United States.

Ann Clin Microbiol Antimicrob 2019 Aug 21;18(1):24. Epub 2019 Aug 21.

Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, 316 Pharmacy Building, Buffalo, NY, USA.

Background: Antimicrobial resistance is a widely recognized public health threat, and stewardship interventions to combat this problem are well described. Less is known about antifungal stewardship (AFS) initiatives and their influence within the United States. The purpose of this study was to evaluate evidence on the impact of AFS interventions on clinical and performance measures. Read More

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http://dx.doi.org/10.1186/s12941-019-0323-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702721PMC

Hepatosplenic abscesses in an immunocompetent child with cat-scratch disease from Peru.

Ann Clin Microbiol Antimicrob 2019 Jul 15;18(1):23. Epub 2019 Jul 15.

Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia.

Background: Cat-scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae and B. clarridgeiae. The typical manifestations of CSD include regional lymphadenitis and fever. Read More

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http://dx.doi.org/10.1186/s12941-019-0322-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628487PMC
July 2019
3 Reads

Prevalence of Shigella species and its drug resistance pattern in Ethiopia: a systematic review and meta-analysis.

Ann Clin Microbiol Antimicrob 2019 Jul 9;18(1):22. Epub 2019 Jul 9.

School of Nursing and Midwifery, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Background: Shigella species are a major cause of dysentery and may attribute for death worldwide. Currently antibiotic resistance became the critical challenges for management of infectious disease. The aim was to conduct a systematic review and meta-analysis of Shigella species and its drug resistance pattern in Ethiopia. Read More

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http://dx.doi.org/10.1186/s12941-019-0321-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617577PMC
July 2019
4 Reads
1.514 Impact Factor

CRISPR-cas system: biological function in microbes and its use to treat antimicrobial resistant pathogens.

Ann Clin Microbiol Antimicrob 2019 Jul 5;18(1):21. Epub 2019 Jul 5.

China MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.

The development of antibiotic resistance in bacteria is a major public health threat. Infection rates of resistant pathogens continue to rise against nearly all antimicrobials, which has led to development of different strategies to combat the antimicrobial resistance. In this review, we discuss how the newly popular CRISPR-cas system has been applied to combat antibiotic resistance in both extracellular and intracellular pathogens. Read More

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http://dx.doi.org/10.1186/s12941-019-0317-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611046PMC

Antimicrobial consumption in three pediatric and neonatal intensive care units in Saudi Arabia: 33-month surveillance study.

Ann Clin Microbiol Antimicrob 2019 Jul 3;18(1):20. Epub 2019 Jul 3.

Neonatal Intensive Care, King Abdullah Specialized Children's Hospital, MNGHA, Riyadh, Saudi Arabia.

Background: Despite their critical role in antimicrobial stewardship programs, data on antimicrobial consumption among the pediatric and neonatal population is limited internationally and lacking in Saudi Arabia. The current study was done as part of our antimicrobial stewardship activities.

Objectives: To calculate overall and type-specific antimicrobial consumption. Read More

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http://dx.doi.org/10.1186/s12941-019-0320-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607581PMC
July 2019
1 Read

A prospective multicenter study on the evaluation of antimicrobial resistance and molecular epidemiology of multidrug-resistant Acinetobacter baumannii infections in intensive care units with clinical and environmental features.

Ann Clin Microbiol Antimicrob 2019 Jul 2;18(1):19. Epub 2019 Jul 2.

Department of Medical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: Multidrug-resistant (MDR) Acinetobacter baumannii infections are considered as emerging nosocomial infections particularly in patients hospitalized in intensive care units (ICUs). Therefore, reliable detection of MDR strains is crucial for management of treatment but also for epidemiological data collections. The purpose of this study was to compare antimicrobial resistance and the clonal distribution of MDR clinical and environmental A. Read More

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http://dx.doi.org/10.1186/s12941-019-0319-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607529PMC
July 2019
6 Reads

Association of prenatal antibiotics with measures of infant adiposity and the gut microbiome.

Ann Clin Microbiol Antimicrob 2019 Jun 21;18(1):18. Epub 2019 Jun 21.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Background: Prenatal antibiotic exposure has been associated with an altered infant gut microbiome composition and higher risk of childhood obesity, but no studies have examined if prenatal antibiotics simultaneously alter the gut microbiome and adiposity in infants.

Method: In this prospective study (Nurture: recruitment 2013-2015 in North Carolina, United States), we examined in 454 infants the association of prenatal antibiotic exposure (by any prenatal antibiotic exposure; by trimester of pregnancy; by number of courses; by type of antibiotics) with infant age- and sex-specific weight-for-length z score (WFL-z) and skinfold thicknesses (subscapular, triceps, abdominal) at 12 months of age. In a subsample, we also examined whether prenatal antibiotic exposure was associated with alterations in the infant gut microbiome at ages 3 and 12 months. Read More

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http://dx.doi.org/10.1186/s12941-019-0318-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587281PMC
June 2019
22 Reads

Microsporidial keratitis retrospectively diagnosed by ultrastructural study of formalin-fixed paraffin-embedded corneal tissue: a case report.

Ann Clin Microbiol Antimicrob 2019 Jun 10;18(1):17. Epub 2019 Jun 10.

Department of Ophthalmology, Kindai University Faculty of Medicine, 377-2, Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.

Background: The utility of formalin-fixed paraffin-embedded (FFPE) corneal tissue specimens for retrospective diagnosis of microsporidial keratitis was evaluated by transmission electron microscopy (TEM) analysis and the possible second case of microsporidial keratitis after Descemet stripping automated endothelial keratoplasty (DSAEK) was described.

Case Presentation: A 68-year-old man presented with multiple crystalline opacities in the corneal stroma that progressed extremely slowly after DSAEK. Fungiflora Y staining of corneal scrapings from the affected regions revealed an oval microorganism. Read More

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http://dx.doi.org/10.1186/s12941-019-0316-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558824PMC
June 2019
12 Reads
1.514 Impact Factor

Whole-genome sequencing and characterization of an antibiotic resistant Neisseria meningitidis B isolate from a military unit in Vietnam.

Ann Clin Microbiol Antimicrob 2019 May 6;18(1):16. Epub 2019 May 6.

Laboratory of Molecular Microbiology, Institute of Biotechnology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay District, Hanoi, Vietnam.

Background: Invasive meningococcal disease (IMD) persists in military units in Vietnam despite the availability of antibiotics and vaccines. A hindrance to reducing the incidence of IMD in Vietnam is a lack of molecular data from isolates of the causative agent, Neisseria meningitidis from this country. Here, we characterized key genetic and epidemiological features of an invasive N. Read More

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http://dx.doi.org/10.1186/s12941-019-0315-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501280PMC
May 2019
7 Reads
1.514 Impact Factor

Late prosthetic valve endocarditis with Mycobacterium tuberculosis after the Bentall procedure.

Ann Clin Microbiol Antimicrob 2019 Mar 28;18(1):15. Epub 2019 Mar 28.

Department of Infectious Diseases, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, China.

Background: Prosthetic valve endocarditis (PVE) is a rare but severe complication of valve replacement surgery, with an incidence rate of 0.3-1.2% per patient-year. Read More

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http://dx.doi.org/10.1186/s12941-019-0314-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437957PMC
March 2019
10 Reads
1.514 Impact Factor

Streptococcus agalactiae maternal colonization, antibiotic resistance and serotype profiles in Africa: a meta-analysis.

Ann Clin Microbiol Antimicrob 2019 Mar 28;18(1):14. Epub 2019 Mar 28.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Maternal rectovaginal colonization with Streptococcus agalactiae (Group B Streptococcus or GBS) is the most common route for the GBS disease in the perinatal period. The knowledge of maternal colonization, antibiotic resistance and serotype profiles is substantially needed to formulate the broad vaccine. However, it has not been estimated in Africa. Read More

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http://dx.doi.org/10.1186/s12941-019-0313-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437888PMC
March 2019
3 Reads