613 results match your criteria Annals of Clinical Microbiology and Antimicrobials[Journal]


Characterization of the clonal profile of methicillin resistant Staphylococcus aureus isolated from patients with early post-operative orthopedic implant based infections.

Ann Clin Microbiol Antimicrob 2019 Feb 13;18(1). Epub 2019 Feb 13.

Division of Bacteriology, National Institute of Cholera and Enteric Diseases, Kolkata, India.

Background: To analyze the molecular epidemiology and to compare between the major methicillin resistant Staphylococcus aureus biotypes for association with patient characteristics who had an implant for closed fracture and developed early post-operative wound infections (POWI) in a tertiary care hospital of India.

Methods: Pulsed-field gel electrophoresis (PFGE), antimicrobial resistance, accessory gene regulator (agr) and staphylococcal cassette chromosome mec (SCCmec) types, Paton-Valentine leukocidin (PVL) gene, toxin gene profiling, biofilm formation and patient demographics were correlated with MLST clonal complexes (CC).

Findings: Overall eight different sequence types (STs) were detected with a predominance of ST239 (66%), ST22 (18%) and some minor types ST772, ST30 (4% each) ST1, ST642, ST6, ST107 (2% each). Read More

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http://dx.doi.org/10.1186/s12941-019-0307-zDOI Listing
February 2019

Accurate identification and epidemiological characterization of Burkholderia cepacia complex: an update.

Ann Clin Microbiol Antimicrob 2019 Feb 4;18(1). Epub 2019 Feb 4.

Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, 632004, India.

Bacteria belonging to the Burkholderia cepacia complex (Bcc) are among the most important pathogens isolated from cystic fibrosis (CF) patients and in hospital acquired infections (HAI). Accurate identification of Bcc is questionable by conventional biochemical methods. Clonal typing of Burkholderia is also limited due to the problem with identification. Read More

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http://dx.doi.org/10.1186/s12941-019-0306-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360774PMC
February 2019

Antimicrobial stewardship program (ASP): an effective implementing technique for the therapy efficiency of meropenem and vancomycin antibiotics in Iranian pediatric patients.

Ann Clin Microbiol Antimicrob 2019 Jan 29;18(1). Epub 2019 Jan 29.

Department of Pediatric Infection Disease, Bahrami Hospital, Tehran University of Medical Science, Shahid Kiaee Street (Ghasem Abad), Damavand Street, 1641744991, Tehran, Iran.

Background: Antimicrobial stewardship program (ASP) is a distinguished method to improve the prescription and efficacy of antibiotics.

Aim: The efficacy of ASP and conventional methods was compared to measure the effectiveness of meropenem (MPM) and vancomycin (VMN) antibiotics in pediatric patients.

Design: In an interventional quasi-experimental study, 135 children admitted in Children's Hospital affiliated to University of Medical Sciences in time periods of 2014-2015 and 2015-2016 were assessed. Read More

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http://dx.doi.org/10.1186/s12941-019-0305-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352345PMC
January 2019

The effect of malaria rapid diagnostic tests results on antimicrobial prescription practices of health care workers in Burkina Faso.

Ann Clin Microbiol Antimicrob 2019 Jan 28;18(1). Epub 2019 Jan 28.

Parasitology Unit, Department of Medical Microbiology, Amsterdam University Medical Centers, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Background: Malaria rapid diagnostic tests (RDT) are widely used in endemic areas in order to comply with the recommendation that malaria treatment should only be given after the clinical diagnosis has been confirmed by RDT or microscopy. However, the overestimation of malaria infection with the use of PfHRP2 based RDT, makes the management of febrile illnesses more challenging. This study aimed to assess the effect of the use of malaria RDT on antimicrobial prescription practices. Read More

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http://dx.doi.org/10.1186/s12941-019-0304-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348635PMC
January 2019

Hypervirulent Klebsiella pneumoniae (hypermucoviscous and aerobactin positive) infection over 6 years in the elderly in China: antimicrobial resistance patterns, molecular epidemiology and risk factor.

Authors:
Chao Liu Jun Guo

Ann Clin Microbiol Antimicrob 2019 Jan 21;18(1). Epub 2019 Jan 21.

Department of Respiratory Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, No. 168 Litang Road, Changping District, Beijing, 102218, China.

Background: The definition of hypervirulent Klebsiella pneumoniae (hvKp), traditionally regarded as hypermucoviscosity, is controversial. However, data based on both phenotype (hypermucoviscous) and genetic (aerobactin) criteria are limited.

Methods: A retrospective study was conducted in 175 geriatric patients between January 2008 and January 2014. Read More

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http://dx.doi.org/10.1186/s12941-018-0302-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341648PMC
January 2019
2 Reads

Streptococcus agalactiae from Ethiopian pregnant women; prevalence, associated factors and antimicrobial resistance: alarming for prophylaxis.

Ann Clin Microbiol Antimicrob 2019 Jan 19;18(1). Epub 2019 Jan 19.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P. O. Box 196, Gondar, Ethiopia.

Background: Maternal Streptococcus agalactiae (Group B Streptococcus, GBS) colonization rates and its antibiotic resistance patterns provide important information useful in guiding prevention strategies. There is a paucity of evidence about GBS in the Amhara National Regional State, Ethiopia.

Objective: To determine colonization prevalence, associated risk factors, and antibiotics resistance including inducible clindamycin resistance patterns of GBS among Ethiopian pregnant women. Read More

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http://dx.doi.org/10.1186/s12941-019-0303-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339690PMC
January 2019
1 Read

Application of next-generation sequencing to detect variants of drug-resistant Mycobacterium tuberculosis: genotype-phenotype correlation.

Ann Clin Microbiol Antimicrob 2019 Jan 3;18(1). Epub 2019 Jan 3.

Department of Laboratory Medicine, Hallym University College of Medicine, Chuncheon, South Korea.

Background: Drug resistance in Mycobacterium tuberculosis (MTB) is a major health issue worldwide. Recently, next-generation sequencing (NGS) technology has begun to be used to detect resistance genes of MTB. We aimed to assess the clinical usefulness of Ion S5 NGS TB research panel for detecting MTB resistance in Korean tuberculosis patients. Read More

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http://dx.doi.org/10.1186/s12941-018-0300-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317249PMC
January 2019
2 Reads

Prevalence of Acinetobacter baumannii in Saudi Arabia: risk factors, antimicrobial resistance patterns and mechanisms of carbapenem resistance.

Ann Clin Microbiol Antimicrob 2019 Jan 3;18(1). Epub 2019 Jan 3.

Department of Basic Medical Science, College of Medicine, University of Bisha, Bisha, Saudi Arabia.

Acinetobacter baumannii is an important opportunistic pathogen due to its capabilities for developing mechanisms of resistance to a wide range of antimicrobial agents including carbapenems. This review described the risk factors, antimicrobial susceptibility and mechanisms of carbapenem resistance of A. baumannii from different geographical regions of Saudi Arabia. Read More

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http://dx.doi.org/10.1186/s12941-018-0301-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317247PMC
January 2019
2 Reads
1.514 Impact Factor

Cerebrospinal fluid penetration of very high-dose meropenem: a case report.

Ann Clin Microbiol Antimicrob 2018 Dec 29;17(1):47. Epub 2018 Dec 29.

Department of Neurosurgery, University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.

Background: Standard dosing of meropenem (2 g t.i.d. Read More

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http://dx.doi.org/10.1186/s12941-018-0299-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310956PMC
December 2018
2 Reads

In vivo efficacy of tobramycin-loaded synthetic calcium phosphate beads in a rabbit model of staphylococcal osteomyelitis.

Ann Clin Microbiol Antimicrob 2018 Dec 28;17(1):46. Epub 2018 Dec 28.

Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.

Background: Osteomyelitis is an acute or chronic inflammatory process of the bone following infection with pyogenic organisms like Staphylococcus aureus. Tobramycin (TOB) is a promising aminoglycoside antibiotic used to treat various bacterial infections, including S. aureus. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0296-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309062PMC
December 2018
8 Reads
1.514 Impact Factor

Metagenomic next-generation sequencing as a diagnostic tool for toxoplasmic encephalitis.

Ann Clin Microbiol Antimicrob 2018 Dec 26;17(1):45. Epub 2018 Dec 26.

Department of Clinical Research Center, the Second Hospital of Nanjing, Nanjing University of Chinese Medicine, 1-1 Zhongfu Road, Nanjing, 210003, China.

Background: More than 100 different pathogens can cause encephalitis. Testing of all the neurological pathogens by conventional methods can be difficult. Metagenomic next-generation sequencing (NGS) could identify the infectious agents in a target-independent manner. Read More

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http://dx.doi.org/10.1186/s12941-018-0298-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305995PMC
December 2018
2 Reads

Detection of bacterial DNA from central venous catheter removed from patients by next generation sequencing: a preliminary clinical study.

Ann Clin Microbiol Antimicrob 2018 Dec 22;17(1):44. Epub 2018 Dec 22.

Department of Bacteriology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo, 105-8461, Japan.

Background: Catheter-related infection (CRI) is one of the serious challenges in clinical practice. This preliminary clinical study aimed to examine whether next-generation sequencing (NGS) targeting 16S rDNA, which was PCR-amplified directly from the tip of a central venous catheter (CVC), can be used to identify causative pathogens in CRI, compared to the culture method.

Methods: Hospitalized patients, from whom a CVC had just been removed, were prospectively enrolled and divided into the CRI-suspected and routine removal groups. Read More

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http://dx.doi.org/10.1186/s12941-018-0297-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303997PMC
December 2018
2 Reads

Identification of pathogens in culture-negative infective endocarditis cases by metagenomic analysis.

Ann Clin Microbiol Antimicrob 2018 Dec 20;17(1):43. Epub 2018 Dec 20.

State Key Laboratory of Cardiovascular Disease, Beijing Key Laboratory for Molecular Diagnostics of Cardiovascular Diseases, Diagnostic Laboratory Service, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

Background: Pathogens identification is critical for the proper diagnosis and precise treatment of infective endocarditis (IE). Although blood and valve cultures are the gold standard for IE pathogens detection, many cases are culture-negative, especially in patients who had received long-term antibiotic treatment, and precise diagnosis has therefore become a major challenge in the clinic. Metagenomic sequencing can provide both information on the pathogenic strain and the antibiotic susceptibility profile of patient samples without culturing, offering a powerful method to deal with culture-negative cases. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0294-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300891PMC
December 2018
12 Reads

Adherent/invasive Escherichia coli (AIEC) isolates from asymptomatic people: new E. coli ST131 O25:H4/H30-Rx virotypes.

Ann Clin Microbiol Antimicrob 2018 Dec 10;17(1):42. Epub 2018 Dec 10.

Benemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.

Background: The widespread Escherichia coli clone ST131 implicated in multidrug-resistant infections has been recently reported, the majority belonging to O25:H4 serotype and classified into five main virotypes in accordance with the virulence genes carried.

Methods: Pathogenicity Islands I and II (PAI-I and PAI-II) were determined using conventional PCR protocols from a set of four E. coli CTX ST131 O25:H4/H30-Rx strains collected from healthy donors' stool. Read More

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http://dx.doi.org/10.1186/s12941-018-0295-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287351PMC
December 2018
1 Read

Microbial virulence, molecular epidemiology and pathogenic factors of fluoroquinolone-resistant Haemophilus influenzae infections in Guangzhou, China.

Ann Clin Microbiol Antimicrob 2018 Nov 23;17(1):41. Epub 2018 Nov 23.

Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.

Background: Fluoroquinolone-resistant Haemophilus influenzae (FRHI) has been reported worldwide but remain unclear in China.

Methods: A total of 402 H. influenzae isolates collected from 2016 to 2017 were included. Read More

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http://dx.doi.org/10.1186/s12941-018-0290-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251178PMC
November 2018
13 Reads

Culture- and PCR-based detection of BV associated microbiological profile of the removed IUDs and correlation with the time period of IUD in place and the presence of the symptoms of genital tract infection.

Ann Clin Microbiol Antimicrob 2018 Nov 22;17(1):40. Epub 2018 Nov 22.

Institute of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, Faculty of Medicine, University of Szeged, Semmelweis St. 6, Szeged, 6725, Hungary.

Objectives: The long-term use of intrauterine devices (IUDs) may lead to biofilm formation on the surface. The aim of this study was to perform the culture- and PCR-based detection of bacteria/fungi from the biofilm of the removed IUDs with different time periods in place.

Methods: For a 2-year period, 100 IUD users were involved in the study. Read More

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http://dx.doi.org/10.1186/s12941-018-0293-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249738PMC
November 2018
11 Reads

Appropriateness of empiric antimicrobial therapy with imipenem/colistin in severe septic patients: observational cohort study.

Ann Clin Microbiol Antimicrob 2018 Nov 16;17(1):39. Epub 2018 Nov 16.

Medical Intensive Care Unit, University Hospital Center La Rabta, La Rabta Jebbari, 1007, Tunis, Tunisia.

Background: Empiric antimicrobial therapy (EAMT) using imipenem/colistin is commonly prescribed as a first line therapy in critically ill patients with severe sepsis. We aimed to assess the appropriateness of prescribing imipenem/colistin as EAMT in ICU patients.

Methods: A 3-year observational prospective study included ICU patients that required imipenem/colistin as EAMT. Read More

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http://dx.doi.org/10.1186/s12941-018-0292-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240296PMC
November 2018
11 Reads

Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains.

Ann Clin Microbiol Antimicrob 2018 Oct 20;17(1):38. Epub 2018 Oct 20.

Department of Bacteriology, Hospices Civils de Lyon, Hôpital de la Croix-Rousse, Centre de Biologie Nord, Lyon, France.

Clindamycin is a protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus. Recent guidelines recommend the use of clindamycin for the treatment of toxin-mediated infections. Clindamycin modulates virulence expression at sub-inhibitory concentrations (sub-MICs) in clindamycin-susceptible S. Read More

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http://dx.doi.org/10.1186/s12941-018-0291-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195712PMC
October 2018
3 Reads

An update on gastrointestinal endoscopy-associated infections and their contributing factors.

Ann Clin Microbiol Antimicrob 2018 Oct 10;17(1):36. Epub 2018 Oct 10.

Ingham Institute for Applied Medical Research, 1 Campbell Street, Sydney, NSW, 2560, Australia.

Introduction: During clinical use, gastrointestinal endoscopes are grossly contaminated with patient's native flora. These endoscopes undergo reprocessing to prevent infectious transmission upon future use. Endoscopy-associated infections and outbreaks have been reported, with a recent focus on the transmission of multi-drug resistant organisms. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0289-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182826PMC
October 2018
9 Reads

Impact of the use of local fidaxomicin treatment algorithms for managing Clostridium difficile infection in hospitalized patients in southeastern United States.

Ann Clin Microbiol Antimicrob 2018 Oct 11;17(1):37. Epub 2018 Oct 11.

Merck & Co., Inc., Kenilworth, NJ, USA.

Background: Clostridium difficile-associated diarrhea (CDAD) is a major public health threat that results in increased length of stay, hospital readmissions, deaths, and economic burden. CDAD treatment is often guided by severity of disease. Although various tools exist to determine CDAD severity, real-world data evaluating the use of such tools in treatment algorithms are sparse. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s12941-018-0288-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180459PMC
October 2018
14 Reads

Mycetoma: a clinical dilemma in resource limited settings.

Ann Clin Microbiol Antimicrob 2018 Aug 10;17(1):35. Epub 2018 Aug 10.

Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.

Background: Mycetoma is a chronic mutilating disease of the skin and the underlying tissues caused by fungi or bacteria. Although recently included in the list of neglected tropical diseases by the World Health Organization, strategic control and preventive measures are yet to be outlined. Thus, it continues to pose huge public health threat in many tropical and sub-tropical countries. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0287-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085652PMC
August 2018
12 Reads
1.514 Impact Factor

An evaluation of multidrug-resistant Escherichia coli isolates in urinary tract infections from Aguascalientes, Mexico: cross-sectional study.

Ann Clin Microbiol Antimicrob 2018 Jul 24;17(1):34. Epub 2018 Jul 24.

Laboratorio de Biología Celular y Tisular, Departamento de Morfología, Universidad Autónoma de Aguascalientes, Av. Universidad 940, Col. Cd. Universitaria, 20131, Aguascalientes, Mexico.

Background: Uropathogenic Escherichia coli (UPEC) are one of the main bacteria causing urinary tract infections (UTIs). The rates of UPEC with high resistance towards antibiotics and multidrug-resistant bacteria have increased dramatically in recent years and could difficult the treatment.

Methods: The aim of the study was to determine multidrug-resistant bacteria, antibiotic resistance profile, virulence traits, and genetic background of 110 E. Read More

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http://dx.doi.org/10.1186/s12941-018-0286-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057003PMC
July 2018
16 Reads

The Dengue virus in Nepal: gaps in diagnosis and surveillance.

Ann Clin Microbiol Antimicrob 2018 Jul 16;17(1):32. Epub 2018 Jul 16.

International Vaccine Institute, Seoul, Republic of Korea.

Background: The introduction of the dengue virus (DENV) in Nepal is recent, first reports date back to 2004 from a Japanese traveller and limited information is available about DENV infection in the Nepali population. Within a decade after the first DENV detection, it is now endemic in multiple districts of Nepal with approximately 11.2 million people residing in the Terai belt being at risk of DENV infection. Read More

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http://dx.doi.org/10.1186/s12941-018-0284-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047123PMC
July 2018
14 Reads

Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain.

Ann Clin Microbiol Antimicrob 2018 Jul 16;17(1):33. Epub 2018 Jul 16.

Department of Biology, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok, 10520, Thailand.

Background: Aminoglycosides such as amikacin and kanamycin are effective injectable second-line drugs for treatment of multidrug-resistant tuberculosis. Molecular mechanisms underlying aminoglycoside resistance are not well understood. We have previously identified the amikacin- and kanamycin-resistant M. Read More

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http://dx.doi.org/10.1186/s12941-018-0285-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047124PMC
July 2018
7 Reads

Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection.

Ann Clin Microbiol Antimicrob 2018 Jul 9;17(1):31. Epub 2018 Jul 9.

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Background: Streptococcus pyogenes is an uncommon pathogen of purpura fulminans, and the pathogenesis of S. pyogenes-purpura fulminans remains unclear because of paucity of cases. We reported a pediatric case of S. Read More

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http://dx.doi.org/10.1186/s12941-018-0282-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036671PMC
July 2018
7 Reads

Predictor of multidrug resistant tuberculosis in southwestern part of Ethiopia: a case control study.

Ann Clin Microbiol Antimicrob 2018 Jul 3;17(1):30. Epub 2018 Jul 3.

Oromia Regional Health Bureau, Addis Ababa, Ethiopia.

Background: Curable disease tuberculosis is becoming incurable or difficult to treat due to drug resistance. Multi drug resistance tuberculosis is a major health problem for less developed countries. Development of drug resistance is mainly as result of man related factors and poor lifestyle. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0283-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029339PMC
July 2018
30 Reads

Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication.

Ann Clin Microbiol Antimicrob 2018 Jun 28;17(1):29. Epub 2018 Jun 28.

Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan.

Background: All Helicobacter pylori-infected patients are recommended for eradication with an appropriate regimen in each geographic area. The choice of the therapy is somewhat dependent on the antimicrobial susceptibility. The rate of clarithromycin resistance has been increasing and is associated with failure; thus, susceptibility testing is recommended before triple therapy with clarithromycin. Read More

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http://dx.doi.org/10.1186/s12941-018-0281-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022507PMC
June 2018
8 Reads

The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China.

Ann Clin Microbiol Antimicrob 2018 Jun 26;17(1):28. Epub 2018 Jun 26.

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200433, China.

Background: The group B Streptococcus (GBS) is a human commensal bacterium, which is capable of causing several infectious diseases in infants, and people with chronic diseases. GBS has been the most common cause of infections in urinary tract of the elders, but relatively few studies reported the urine-isolated GBS and their antimicrobial susceptibilities. Hence, we decided to investigate GBS specially isolated from urine in Suzhou, China. Read More

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http://dx.doi.org/10.1186/s12941-018-0280-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020191PMC
June 2018
11 Reads

Antimicrobial misuse in pediatric urinary tract infections: recurrences and renal scarring.

Ann Clin Microbiol Antimicrob 2018 Jun 25;17(1):27. Epub 2018 Jun 25.

Department of Pediactrics, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.

Background: In children, urinary tract infection (UTI) is one of a common bacterial infection. This study was conducted to detect the uropathogen, antimicrobial susceptibility, pathogen associated with recurrences and renal scarring in children initially taken care from general practitioners and later presented to tertiary care.

Methods: Every inward UTI episode, culture and antimicrobial susceptibility was done while on past 6-month, history of infections and use of antimicrobials was collected using clinical records and demonstration of antimicrobials. Read More

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http://dx.doi.org/10.1186/s12941-018-0279-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016131PMC
June 2018
5 Reads

Infectious disease burden and antibiotic prescribing in primary care in Israel.

Ann Clin Microbiol Antimicrob 2018 Jun 9;17(1):26. Epub 2018 Jun 9.

The Faculty of Medicine in the Galilee, Bar Ilan University, Zefat, Israel.

Background: Antibiotics are frequently prescribed at many of the visits to primary care clinics, often for conditions for which they provide no benefit, including viral respiratory tract infections.

Objectives: The aim was to evaluate primary care visits due to infectious diseases, and to estimate antibiotic prescribing and antibiotic dispensing by pharmacies.

Methods: Diagnosis of infectious disease, antibiotic prescribing and dispensing data at the individual patient level were extracted for 2015 from Clalit Health Services' electronic medical records and linked to determine the condition for which the antimicrobial was prescribed. Read More

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http://dx.doi.org/10.1186/s12941-018-0278-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994243PMC
June 2018
16 Reads

Detection of urinary Chlamydia trachomatis, Mycoplasma genitalium and human papilloma virus in the first trimester of pregnancy by PCR method.

Ann Clin Microbiol Antimicrob 2018 Jun 4;17(1):25. Epub 2018 Jun 4.

Almahdi Kheyrieh Clinics, Tehran, Iran.

Background: Miscarriage and preterm delivery are the most important challenges of pregnancy. Different bacterial and viral infection may cause miscarriage and preterm delivery. Among bacterial factors, Mycoplasma genitalium and Chlamydia trachomatis have the most important role and human papilloma virus (HPV) is the leading viral factor in this regard. Read More

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http://dx.doi.org/10.1186/s12941-018-0276-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985560PMC
June 2018
22 Reads

Association of virulence gene expression with colistin-resistance in Acinetobacter baumannii: analysis of genotype, antimicrobial susceptibility, and biofilm formation.

Ann Clin Microbiol Antimicrob 2018 Jun 1;17(1):24. Epub 2018 Jun 1.

Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, 100 Poursina Ave., 100 Keshavarz Blvd, Tehran, 14167-53955, Iran.

Background: Acinetobacter baumannii causes difficult-to-treat nosocomial infections, which often lead to morbidity due to the development of antimicrobial drug resistance and expression of virulence genes. Data regarding the association of resistance to colistin, a last treatment option, and the virulence gene expression of A. baumannii is scarce. Read More

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http://dx.doi.org/10.1186/s12941-018-0277-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984448PMC
June 2018
8 Reads

Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli: comparison between Etest and a broth dilution method.

Ann Clin Microbiol Antimicrob 2018 May 23;17(1):23. Epub 2018 May 23.

Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, Hanna Senesh 818/2, Tiberias, Israel.

Background: Campylobacter is a leading cause of foodborne gasteroenteritis worldwide. Antimicrobial susceptibility testing for Campylobacter spp. is not routinely performed by most clinical laboratories. Read More

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http://dx.doi.org/10.1186/s12941-018-0275-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964680PMC
May 2018
4 Reads

Rapid detection of carbapenemase activity of Enterobacteriaceae isolated from positive blood cultures by MALDI-TOF MS.

Ann Clin Microbiol Antimicrob 2018 May 18;17(1):22. Epub 2018 May 18.

Department of Clinical Laboratory, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Yangpu District, Shanghai, 200092, China.

Background: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been proved to be a useful tool for identification of pathogens directly isolated from blood cultures in clinical microbiology laboratories. β-Lactam antibiotics are commonly used for treatment of bloodstream infections caused by Enterobacteriaceae strains, and carbapenem is the superlative class of β-lactam antibiotics. Since the carbapenem resistance rate of Enterobacteriaceae strains raised year by year, efficient detection of carbapenemase activity and timely delivery of carbapenem susceptibility reports of Enterobacteriaceae strains isolated from blood cultures is important for clinicians. Read More

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http://dx.doi.org/10.1186/s12941-018-0274-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960105PMC
May 2018
9 Reads
1.514 Impact Factor

Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review.

Ann Clin Microbiol Antimicrob 2018 May 10;17(1):21. Epub 2018 May 10.

Division of Infectious Disease, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.

Background: Mycotic aneurysm is an uncommon disease which could be fatal without appropriate treatment. Although standard therapy for mycotic aneurysms consists of resection of the infected aorta and in situ graft replacement, some treat with endovascular stent-grafting because patients may not tolerate graft replacement due to underlying diseases. There are 6 more reported cases of mycotic aneurysm caused by Edwardsiella tarda. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0273-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944098PMC
May 2018
15 Reads

Nasal colonization with methicillin-resistant Staphylococcus aureus among elderly living in nursing homes in Brazil: risk factors and molecular epidemiology.

Ann Clin Microbiol Antimicrob 2018 May 4;17(1):18. Epub 2018 May 4.

Department of Tropical Diseases, Botucatu School of Medicine, University Hospital, UNESP-Univ Estadual Paulista, Botucatu, SP, Brazil.

Background: Methicillin-resistant Staphylococcus aureus poses a threat to elderly living in nursing homes. Studies focusing on the epidemiology of colonization may help in the design of infection control strategies.

Objective: To identify factors associated with MRSA colonization and the dissemination of clones among nursing home residents. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0271-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934845PMC
May 2018
5 Reads

Emergence of multidrug-resistant Providencia rettgeri isolates co-producing NDM-1 carbapenemase and PER-1 extended-spectrum β-lactamase causing a first outbreak in Korea.

Ann Clin Microbiol Antimicrob 2018 May 5;17(1):20. Epub 2018 May 5.

Department of Laboratory Medicine, Hallym University College of Medicine, Seoul, South Korea.

Background: Nosocomial outbreak due to carbapenem-resistant Enterobacteriaceae has become serious challenge to patient treatment and infection control. We describe an outbreak due to a multidrug-resistant Providencia rettgeri from January 2016 to January 2017 at a University Hospital in Seoul, Korea.

Methods: A total of eight non-duplicate P. Read More

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http://dx.doi.org/10.1186/s12941-018-0272-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935979PMC
May 2018
6 Reads

Raoultella planticola bacteremia-induced fatal septic shock following burn injury.

Ann Clin Microbiol Antimicrob 2018 May 4;17(1):19. Epub 2018 May 4.

Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama, 700-8558, Japan.

Background: Raoultella planticola, a Gram-negative, aerobic bacillus commonly isolated from soil and water, rarely causes invasive infections in humans. Septic shock from R. planticola after burn injury has not been previously reported. Read More

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http://dx.doi.org/10.1186/s12941-018-0270-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934804PMC
May 2018
12 Reads

Hepatitis E virus infection in Turkey: a systematic review.

Ann Clin Microbiol Antimicrob 2018 May 2;17(1):17. Epub 2018 May 2.

Medilife Hospital, Istanbul, Turkey.

Hepatitis E virus (HEV), a non-enveloped single stranded RNA virus causes sporadic cases of hepatitis or outbreaks. The disease is generally self-limited although it may cause fulminant hepatitis in pregnant women, elderly, those with underlying chronic hepatitis, immunosuppressed, and transplant recipients. It is transmitted through fecal-oral route and zoonotic transmission. Read More

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http://dx.doi.org/10.1186/s12941-018-0269-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930810PMC
May 2018
4 Reads

Ginger (Zingiber officinale) phytochemicals-gingerenone-A and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches.

Ann Clin Microbiol Antimicrob 2018 Apr 2;17(1):16. Epub 2018 Apr 2.

Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University, Jinju, 52828, Republic of Korea.

Background: Antibiotic resistance is a defense mechanism, harbored by pathogens to survive under unfavorable conditions. Among several antibiotic resistant microbial consortium, Staphylococcus aureus is one of the most havoc microorganisms. Staphylococcus aureus encodes a unique enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (SaHPPK), against which, none of existing antibiotics have been reported. Read More

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http://dx.doi.org/10.1186/s12941-018-0266-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879566PMC
April 2018
21 Reads
1.510 Impact Factor

Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study.

Ann Clin Microbiol Antimicrob 2018 Mar 23;17(1):15. Epub 2018 Mar 23.

Department of Internal Medicine & Critical Care Medicine, Max Smart Super Speciality Hospital, Saket, New Delhi, India.

Background: The most important concern with polymyxins (Colistin and Polymyxin B) use is nephrotoxicity. There is no prospective data comparing nephrotoxicity of these two drugs, when administered in high doses and as per current recommendations. We conducted a prospective study to compare their trend of nephrotoxicity in our patient population. Read More

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http://dx.doi.org/10.1186/s12941-018-0262-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865377PMC
March 2018
8 Reads

Detection of Neisseria meningitidis in a paediatric patient with septic arthritis using multiplexed diagnostic PCR targeting meningitis/encephalitis (ME).

Ann Clin Microbiol Antimicrob 2018 Mar 23;17(1):14. Epub 2018 Mar 23.

Centre for Interventions in Infection, Inflammation & Immunity (4i) and Graduate Entry Medical School, University of Limerick, Limerick, Ireland.

Background: Neisseria meningitidis is associated with meningitis and septicemia. Septic meningococcal arthritis is relatively uncommon and its diagnosis associated with clinical and microbiological challenges. Early recognition and treatment is required to prevent joint destruction. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0268-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865334PMC
March 2018
14 Reads

Genetic contexts related to the diffusion of plasmid-mediated CTX-M-55 extended-spectrum beta-lactamase isolated from Enterobacteriaceae in China.

Ann Clin Microbiol Antimicrob 2018 Mar 23;17(1):12. Epub 2018 Mar 23.

Department of Clinical Laboratory, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

Background: CTX-M-55 extended-spectrum beta-lactamases are being rapidly disseminated and transmitted in clinical practices around the world. The genetic contexts of the transferable plasmid-mediated bla gene in Enterobacteriaceae were detected and characterized in this study.

Methods: Isolates were obtained from the First Affiliated Hospital of Zhengzhou University between September 2015 and March 2016. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0265-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865355PMC
March 2018
10 Reads

Factors associated to prevalence and treatment of carbapenem-resistant Enterobacteriaceae infections: a seven years retrospective study in three tertiary care hospitals.

Ann Clin Microbiol Antimicrob 2018 Mar 23;17(1):13. Epub 2018 Mar 23.

Department of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, People's Republic of China.

Background: The increasing incidence of carbapenem-resistant Enterobacteriaceae (CRE), has resulted in a difficult problem in the current clinical anti-infective treatment. We performed a retrospective analysis of prevalence and treatment for CRE infections patients.

Methods: This study was conducted in three tertiary care hospitals from January 1, 2010 to December 30, 2016. Read More

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http://dx.doi.org/10.1186/s12941-018-0267-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865290PMC
March 2018
8 Reads

A case of Cardiobacterium valvarum endocarditis with cerebral hemorrhage after MVR, TVP and vegetation removal operation.

Ann Clin Microbiol Antimicrob 2018 Mar 22;17(1):11. Epub 2018 Mar 22.

Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.

Background: Cardiobacterium is a fastidious Gram-negative bacillus, and is a rare human pathogen in clinical settings. Herein, we describe a case of Cardiobacterium valvarum (C. valvarum) endocarditis with a rare complication of cerebral hemorrhage after mitral valve replacement (MVR), tricuspid valve prosthesis (TVP) and vegetation removal operation. Read More

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http://dx.doi.org/10.1186/s12941-018-0263-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863452PMC
March 2018
10 Reads

Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene.

Ann Clin Microbiol Antimicrob 2018 Mar 22;17(1):10. Epub 2018 Mar 22.

Department of Gastroenterology, Sanmen People's Hospital, No. 117, Renmin Road, Sanmen, 317100, Zhejiang, People's Republic of China.

Background: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR resistance has been clearly understood in H. pylori, it is lack of evidence of other genes involved in drug resistance. Read More

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http://dx.doi.org/10.1186/s12941-018-0259-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863438PMC
March 2018
10 Reads

Prenatal and postnatal antibiotic exposure influences the gut microbiota of preterm infants in neonatal intensive care units.

Ann Clin Microbiol Antimicrob 2018 Mar 19;17(1). Epub 2018 Mar 19.

Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China.

Background: To explore the influences of prenatal antibiotic exposure, the intensity of prenatal and postnatal antibiotic exposure on gut microbiota of preterm infants and whether gut microbiota and drug resistant strains in the neonatal intensive care unit (NICU) over a defined period are related.

Methods: Among 28 preterm infants, there were two groups, the PAT (prenatal antibiotic therapy) group (12 cases), and the PAF (prenatal antibiotic free) group (12 cases). Fecal samples from both groups were collected on days 7 and 14. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0264-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858143PMC
March 2018
16 Reads

Comparative and molecular analysis of MRSA isolates from infection sites and carrier colonization sites.

Ann Clin Microbiol Antimicrob 2018 Mar 15;17(1). Epub 2018 Mar 15.

Department of Biochemistry, College of Medicine, Imam Abdulrahman Bin Faisal University (IAU), P.O. Box 1982, Dammam, 31441, Saudi Arabia.

Background: Methicillin resistant Staphylococcus aureus (MRSA) constitutes a major global health concern causing hospital and community acquired infections. A wide diversity of MRSA genotypes are circulating in geographically related regions. Therefore understanding the molecular epidemiology of MRSA is fundamental to design control and clearance measures. Read More

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http://dx.doi.org/10.1186/s12941-018-0260-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852952PMC
March 2018
13 Reads

Quality control of malaria microscopy reveals misdiagnosed non-falciparum species and other microscopically detectable pathogens in Senegal.

Ann Clin Microbiol Antimicrob 2018 Mar 15;17(1). Epub 2018 Mar 15.

Laboratory of Parasitology and Mycology, Cheikh Anta Diop University, Avenue Cheikh Anta Diop, BP 5005 Fann, Dakar, Senegal.

Background: In developing countries, malaria diagnosis relies on microscopy and rapid diagnostic tests. In Senegal, national malaria control program (NMCP) regularly conducts supervisory visits in health services where malaria microscopy is performed. In this study, expert microscopists assessed the performance of laboratory technicians in malaria microscopy. Read More

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https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12941-018-0261-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853095PMC
March 2018
12 Reads

Dengue periodic outbreaks and epidemiological trends in Nepal.

Ann Clin Microbiol Antimicrob 2018 Feb 23;17(1). Epub 2018 Feb 23.

Virology Unit, Central Department of Biotechnology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.

Dengue is a global health problem and expansion of its endemics towards new territories in the hilly regions in Nepal is a serious concern. It appeared as a new disease in Nepal in 2004 from Japanese traveler with sporadic cases every year and massive outbreaks in 2010, 2013 and 2016. The serotype was responsible for outbreak in particular year was dengue virus serotype-1 (DENV-1) in 2010, 2016; and DENV-2 in 2013. Read More

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http://dx.doi.org/10.1186/s12941-018-0258-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824540PMC
February 2018
13 Reads
2 Citations
1.514 Impact Factor