741 results match your criteria Annals of Clinical Microbiology and Antimicrobials[Journal]


Molecular characteristics of antibiotic-resistant Escherichia coli and Klebsiella pneumoniae strains isolated from hospitalized patients in Tehran, Iran.

Ann Clin Microbiol Antimicrob 2021 Apr 27;20(1):32. Epub 2021 Apr 27.

Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: We evaluated the distribution of carbapenem and colistin resistance mechanisms of clinical E. coli and K. pneumoniae isolates from Iran. Read More

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Novel coronavirus seropositivity and related factors among healthcare workers at a university hospital during the prevaccination period: a cross-sectional study.

Ann Clin Microbiol Antimicrob 2021 Apr 27;20(1):31. Epub 2021 Apr 27.

Department of Clinical Microbiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.

Background: This study aimed to investigate the specific risk factors for the transmission of novel coronavirus (SARS-CoV-2) among healthcare workers in different campuses of a university hospital and to reveal the risk factors for antibody positivity.

Methods: In this retrospective cross-sectional study, 2988 (82%) of 3620 healthcare workers in a university hospital participated. The coronavirus disease 2019 (COVID-19) antibody was investigated using serum from healthcare workers who underwent COVID-19 antibody testing. Read More

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Bacteriophage therapy for inhibition of multi drug-resistant uropathogenic bacteria: a narrative review.

Ann Clin Microbiol Antimicrob 2021 Apr 26;20(1):30. Epub 2021 Apr 26.

Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Multi-Drug Resistant (MDR) uropathogenic bacteria have increased in number in recent years and the development of new treatment options for the corresponding infections has become a major challenge in the field of medicine. In this respect, recent studies have proposed bacteriophage (phage) therapy as a potential alternative against MDR Urinary Tract Infections (UTI) because the resistance mechanism of phages differs from that of antibiotics and few side effects have been reported for them. Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis are the most common uropathogenic bacteria against which phage therapy has been used. Read More

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The niche of One Health approaches in Lassa fever surveillance and control.

Ann Clin Microbiol Antimicrob 2021 Apr 24;20(1):29. Epub 2021 Apr 24.

The Royal Veterinary College, University of London, Hatfield, UK.

Lassa fever (LF), a zoonotic illness, represents a public health burden in West African countries where the Lassa virus (LASV) circulates among rodents. Human exposure hinges significantly on LASV ecology, which is in turn shaped by various parameters such as weather seasonality and even virus and rodent-host genetics. Furthermore, human behaviour, despite playing a key role in the zoonotic nature of the disease, critically affects either the spread or control of human-to-human transmission. Read More

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Efficacy and safety of azithromycin and amoxicillin/clavulanate for otitis media in children: a systematic review and meta-analysis of randomized controlled trials.

Ann Clin Microbiol Antimicrob 2021 Apr 24;20(1):28. Epub 2021 Apr 24.

Center for Innovative Drug Development and Therapeutic Trials for Africa (CDT Africa), College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Resistance, prolonged therapy, and more adverse reactions made amoxicillin less preferred for treating otitis media. This study aimed to compare the efficacy and safety of azithromycin and amoxicillin/clavulanate for the treatment of otitis media in children.

Methodology: This study was a systematic review and meta-analysis. Read More

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Antibiotic resistance pattern of Bacteroides fragilis isolated from clinical and colorectal specimens.

Ann Clin Microbiol Antimicrob 2021 Apr 23;20(1):27. Epub 2021 Apr 23.

Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Poursina Street, Engelab-e-Eslami Avenue, Tehran, Iran.

Background: Bacteroides fragilis is a part of the normal gastrointestinal flora, but it is also the most common anaerobic bacteria causing the infection. It is highly resistant to antibiotics and contains abundant antibiotic resistance mechanisms.

Methods: The antibiotic resistance pattern of 78 isolates of B. Read More

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Antimicrobial resistance profile and multidrug resistance patterns of Streptococcus pneumoniae isolates from patients suspected of pneumococcal infections in Ethiopia.

Ann Clin Microbiol Antimicrob 2021 Apr 20;20(1):26. Epub 2021 Apr 20.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.

Background: Antimicrobial-resistant strains of Streptococcus pneumoniae have become one of the greatest challenges to global public health today and inappropriate use of antibiotics and high level of antibiotic use is probably the main factor driving the emergence of resistance worldwide. The aim of this study is, therefore, to assess the antimicrobial resistance profiles and multidrug resistance patterns of S. pneumoniae isolates from patients suspected of pneumococcal infections in Ethiopia. Read More

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Molecular characteristics of Staphylococcus aureus strains isolated from nasal samples of sixth year medical students during their pediatric services practices.

Ann Clin Microbiol Antimicrob 2021 Apr 17;20(1):25. Epub 2021 Apr 17.

Department of Pediatric Infectious Disease, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) strains are prevalent in healthcare services. Medical students are at risk for MRSA carriage, subsequent infection and potential transmission of nosocomial infection.Few studies have examined MRSA carriage among medical students. Read More

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The impact of urine microbiota in patients with lower urinary tract symptoms.

Ann Clin Microbiol Antimicrob 2021 Apr 15;20(1):23. Epub 2021 Apr 15.

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Introduction: Inflammation and infection are causative factors of benign prostatic hyperplasia (BPH). Urine is not sterile, and urine microbiota identified by DNA sequencing can play an important role in the development of BPH and can influence the severity of lower urinary tract symptoms (LUTS).

Materials And Methods: We collected mid-stream voided urine samples from BPH patients and control participants and stored them in a freezer at - 80 °C. Read More

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Characterization of antimicrobial susceptibility, extended-spectrum β-lactamase genes and phylogenetic groups of Shigatoxin producing Escherichia coli isolated from patients with diarrhea in Iran.

Ann Clin Microbiol Antimicrob 2021 Apr 15;20(1):24. Epub 2021 Apr 15.

Molecular Biology Department, Pasteur Institute of Iran, Tehran, Iran.

Background: Shiga toxin-producing Escherichia coli (STEC) are among common foodborne bacterial pathogens and healthy livestock are the main source of this bacterium. Severe diseases attribute to two types of cytotoxin Stx1 and Stx2, which are also called Shiga toxin (Stx). Infection of humans with STEC may result in Acute diarrhea with or without bleeding, hemorrhagic colitis (HC) and the hemolytic uremic syndrome (HUS). Read More

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Helicobacter canis bacteraemia in a rheumatoid arthritis patient treated with tofacitinib: case report and literature review.

Ann Clin Microbiol Antimicrob 2021 Apr 8;20(1):22. Epub 2021 Apr 8.

Division of Internal Medicine, Department of Rheumatology, University Medical Centre Maribor, Ljubljanska ulica 5, 2000, Maribor, Slovenia.

Background: Non-Helicobacter pylori species (NHPS) are newly emerging bacteria that naturally inhabit birds and mammals apart from humans and rarely cause diseases in humans. In recent years, a rise in the number of cases associated with NHPS infections in humans has been observed. Among them, infections with Helicobacter (H. Read More

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Low sensitivity of conventional fungal agars in fungemia by Rhodotorula mucilaginosa: description of two cases.

Ann Clin Microbiol Antimicrob 2021 Mar 27;20(1):21. Epub 2021 Mar 27.

Mycology Reference Laboratory, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra Majadahonda-Pozuelo Km2, 28220, Majadahonda, Madrid, Spain.

Background: Although most bloodstream yeast infections are caused by Candida spp., infections by rare or less common species have increased in recent years. Diagnosis of infections caused by these species is difficult due to the lack of specific symptoms and adequate diagnostic tools. Read More

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Retraction Note to: Antimicrobial misuse in pediatric urinary tract infections: recurrences and renal scarring.

Ann Clin Microbiol Antimicrob 2021 Mar 25;20(1):20. Epub 2021 Mar 25.

Department of Pediactrics, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.

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Predominance of international clone 2 multidrug-resistant Acinetobacter baumannii clinical isolates in Thailand: a nationwide study.

Ann Clin Microbiol Antimicrob 2021 Mar 20;20(1):19. Epub 2021 Mar 20.

Department of Microbiology, Faculty of Pharmacy, Mahidol University, 447 Sri Ayudthya Rd, Rajathevi, Bangkok, 10400, Thailand.

Background: Acinetobacter baumannii has emerged as one of the common multidrug resistance pathogens causing hospital-acquired infections. This study was conducted to elucidate the distribution of antimicrobial resistance genes in the bacterial population in Thailand. Multidrug-resistant A. Read More

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Intestinal carriage of vancomycin-resistant Enterococcus spp. among high-risk patients in university hospitals in Serbia: first surveillance report.

Ann Clin Microbiol Antimicrob 2021 Mar 20;20(1):18. Epub 2021 Mar 20.

Department of Bacteriology, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Dr Subotića 1, 11000, Belgrade, Serbia.

Background: The screening for intestinal carriage of vancomycin-resistant Enterococcus spp. (VRE) among high risk patients in the Balkan region and molecular epidemiology of VRE is insufficiently investigated, yet it could be of key importance in infection control. The aim of this study was to provide baseline data on VRE intestinal carriage among high-risk patients in Serbian university hospitals, to determine the phenotypic/genotypic profiles of the isolated VRE, to obtain knowledge of local resistance patterns and bridge the gaps in current VRE surveillance. Read More

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The laboratory findings and different COVID-19 severities: a systematic review and meta-analysis.

Ann Clin Microbiol Antimicrob 2021 Mar 16;20(1):17. Epub 2021 Mar 16.

Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran.

Background: Abnormal laboratory findings are common in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this systematic review was to investigate the effect of the level of some laboratory factors (C-reactive protein (CRP), creatinine, leukocyte count, hemoglobin, and platelet count) on the severity and outcome of coronavirus disease 2019 (COVID-19).

Methods: We searched PubMed, Web of Science, Scopus, and Google Scholar. Read More

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Multidrug resistance and extended-spectrum beta-lactamase producing Gram-negative bacteria from three Referral Hospitals of Amhara region, Ethiopia.

Ann Clin Microbiol Antimicrob 2021 Mar 11;20(1):16. Epub 2021 Mar 11.

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Multidrug resistance (MDR), extended-spectrum beta-lactamase (ESBL) and carbapenemase-producing Gram-negative bacteria (GNB) has become a public health threat worldwide. This threat is worse in developing countries where there is high infectious disease burden and spread of antimicrobial resistance co-exist. The aim of the present study was, therefore, to assess MDR, ESBL and carbapenemase producing GNB from patients attending three selected referral hospitals in Amhara region. Read More

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Effect on 30-day mortality and duration of hospitalization of empirical antibiotic therapy in CRGNB-infected pneumonia.

Ann Clin Microbiol Antimicrob 2021 Mar 7;20(1):15. Epub 2021 Mar 7.

Fourth Affiliated Hospital of Anhui Medical University Laboratory, Hefei, 230012, China.

Background: The objective of this study was to investigate whether unreasonable empirical antibiotic treatment (UEAT) had an impact on 30-day mortality and duration of hospitalization in bacterial pneumonia caused by carbapenem-resistant gram-negative bacteria (CRGNB).

Methods: This was a retrospective cohort study involving CRGNB-infected pneumonia. All CRGNB-infected pneumonia patients received empirical and targeted antibiotic treatment (TAT), and they were divided into reasonable empirical antibiotic treatment (REAT) and UEAT according to whether the empirical antibiotic treatment (EAT) was reasonable. Read More

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An unusual case of Cardiobacterium valvarum causing aortic endograft infection and osteomyelitis.

Ann Clin Microbiol Antimicrob 2021 Feb 27;20(1):14. Epub 2021 Feb 27.

Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Background: HACEK (Haemophilus spp., Aggregatibacter spp., Cardiobacterium spp. Read More

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February 2021

Correlation between antimicrobial resistance and biofilm formation capability among Klebsiella pneumoniae strains isolated from hospitalized patients in Iran.

Ann Clin Microbiol Antimicrob 2021 Feb 15;20(1):13. Epub 2021 Feb 15.

Department of Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Klebsiella pneumoniae is a common cause of nosocomial infections. Antibiotic resistance and ability to form biofilm, as two key virulence factors of K. pneumoniae, are involved in the persistence of infections. Read More

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February 2021

Molecular characterization of methicillin-resistant Staphylococcus aureus among insulin-dependent diabetic individuals in Brazil.

Ann Clin Microbiol Antimicrob 2021 Feb 10;20(1):12. Epub 2021 Feb 10.

Departamento de Ciências Químicas e Biológicas, Instituto de Biociências de Botucatu, UNESP - Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, SP, Brasil.

Background: People with diabetes mellitus, especially insulin-dependent diabetic patients, are a risk group for staphylococcal infections. Asymptomatic infection with Staphylococcus aureus is common and favors dissemination of the microorganism, rendering these individuals a source of infection. This study aimed to characterize the resistance profile, clonal profile and sequence type, as well as to analyze the prevalence and risk factors for nasal and oropharyngeal carriage of methicillin-susceptible (MSSA) and methicillin-resistant S. Read More

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February 2021

Evaluation of efflux pump activity and biofilm formation in multidrug resistant clinical isolates of Pseudomonas aeruginosa isolated from a Federal Medical Center in Nigeria.

Ann Clin Microbiol Antimicrob 2021 Feb 2;20(1):11. Epub 2021 Feb 2.

Molecular Biology and Biotechnology Department, Nigerian Institute of Medical Research (NIMR) Yaba, Lagos, Lagos State, Nigeria.

Background: Pseudomonas aeruginosa an opportunistic pathogen, is widely associated with nosocomial infections and exhibits resistance to multiple classes of antibiotics. The aim of this study was to determine the antibiotic resistance profile, biofilm formation and efflux pump activity of Pseudomonas strains isolated from clinical samples in Abeokuta Ogun state Nigeria.

Methods: Fifty suspected Pseudomonas isolates were characterized by standard biochemical tests and PCR using Pseudomonas species -specific primers. Read More

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February 2021

Role of Williamsia and Segniliparus in human infections with the approach taxonomy, cultivation, and identification methods.

Ann Clin Microbiol Antimicrob 2021 Jan 23;20(1):10. Epub 2021 Jan 23.

Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.

The genera Williamsia and Segniliparus are of aerobic actinomycetes and at the time of writing, they have 12 and 2 species, respectively. These genera cause various infections in humans. In this review, we surveyed their taxonomy, isolation, identification, as well as their role to cause human infections. Read More

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January 2021

Contemporary analysis of ETEST for antibiotic susceptibility and minimum inhibitory concentration agreement against Pseudomonas aeruginosa from patients with cystic fibrosis.

Ann Clin Microbiol Antimicrob 2021 Jan 19;20(1). Epub 2021 Jan 19.

Center for Anti-Infective Research and Development, Hartford Hospital, 80 Seymour Street, Hartford, 06102, CT, USA.

Objectives: Cystic fibrosis (CF) acute pulmonary exacerbations are often caused by Pseudomonas aeruginosa, including multi-drug resistant strains. Optimal antibiotic therapy is required to return lung function and should be guided by in vitro susceptibility results. There are sparse data describing ETEST performance for CF isolates using contemporary isolates, methods and interpretation, as well as novel antibiotics, such as ceftazidime-avibactam and ceftolozane-tazobactam. Read More

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January 2021

MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challenges.

Ann Clin Microbiol Antimicrob 2021 Jan 18;20(1). Epub 2021 Jan 18.

Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Colombia.

The Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has gained research attention worldwide, given the current pandemic. Nevertheless, a previous zoonotic and highly pathogenic coronavirus, the Middle East Respiratory Syndrome coronavirus (MERS-CoV), is still causing concern, especially in Saudi Arabia and neighbour countries. The MERS-CoV has been reported from respiratory samples in more than 27 countries, and around 2500 cases have been reported with an approximate fatality rate of 35%. Read More

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January 2021

A first probable case of SARS-CoV-2 reinfection in Colombia.

Ann Clin Microbiol Antimicrob 2021 01 12;20(1). Epub 2021 Jan 12.

Universidad de Cordoba, Instituto de Investigaciones Biologicas del Tropico, Monteria, Colombia.

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January 2021

Clinico-microbiological profile of Burkholderia cepacia keratitis: a case series.

Ann Clin Microbiol Antimicrob 2021 Jan 7;20(1). Epub 2021 Jan 7.

Department of Ophthalmology, Chang Gung Memorial Hospital, No. 199, Tung-Hwa North Road, Linkou, Taipei, Taiwan.

Background: Burkholderia cepacia, an opportunistic pathogen mainly affecting patients with cystic fibrosis or immunocompromised, has rarely been documented as a cause of corneal infection. The clinical and microbiological profiles of B. cepacia keratitis are reported herein. Read More

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January 2021

Clinical characteristics and predictors of mortality in young adults with severe COVID-19: a retrospective observational study.

Ann Clin Microbiol Antimicrob 2021 Jan 6;20(1). Epub 2021 Jan 6.

Department of Respiratory and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Background And Objective: Little is yet known whether pathogenesis of COVID-19 is different between young and elder patients. Our study aimed to investigate the clinical characteristics and provide predictors of mortality for young adults with severe COVID-19.

Methods: A total of 77 young adults with confirmed severe COVID-19 were recruited retrospectively at Tongji Hospital. Read More

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January 2021

First detection of a plasmid-encoded New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Acinetobacter baumannii using whole genome sequencing, isolated in a clinical setting in Benin.

Ann Clin Microbiol Antimicrob 2021 Jan 6;20(1). Epub 2021 Jan 6.

Microbiologie, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, UCLouvain, Brussels, Belgium.

Background: Carbapenem-resistant Acinetobacter baumannii is considered a top priority pathogen by the World Health Organization for combatting increasing antibiotic resistance and development of new drugs. Since it was originally reported in Klebsiella pneumoniae in 2009, the quick spread of the bla gene encoding a New-Delhi metallo-beta-lactamase-1 (NDM-1) is increasingly recognized as a serious threat. This gene is usually carried by large plasmids and has already been documented in diverse bacterial species, including A. Read More

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January 2021

Dysbiosis of urine microbiota in obstructive urinary retention patients revealed by next-generation sequencing.

Ann Clin Microbiol Antimicrob 2021 Jan 6;20(1). Epub 2021 Jan 6.

Department of Ultrasonography, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Background: Urinary retention (UR) is a common urinary system disease can be caused by urinary tract obstruction with numerous reasons, however, the role of urine microbes in these disorders is still poorly understood. The aim of this study was to identify the urine microbial features of two common types of obstructive UR, caused by urinary stones or urinary tract tumors, with comparison to healthy controls.

Methods: Urine samples were collected from a cohort of 32 individuals with stone UR, 25 subjects with tumor UR and 25 healthy controls. Read More

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January 2021