Search our Database of Scientific Publications and Authors

I’m looking for a

    2030 results match your criteria Annals of Anatomy Anatomischer Anzeiger [Journal]

    1 OF 41

    Musculoskeletal Anatomy Education: Evaluating the Influence of Different Teaching and Learning Activities on Medical Students Perception and Academic Performance.
    Ann Anat 2018 Jun 8;219:44-50. Epub 2018 Jun 8.
    Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada; Pan Am Clinic, Winnipeg, Manitoba, Canada.
    Medical schools have traditionally used a lecture and dissection-based approach for educating students about human anatomy. There is growing interest in the adoption of alternative teaching and learning activities (TLAs) that incorporate the use of cadaveric prosection and computer-based learning into musculoskeletal (MSK) anatomy curricula. The purpose of this investigation was to examine retrospectively how different TLAs influenced student perceptions about learning, and performance on MSK anatomy examinations. Read More

    The Terminologia Histologica after 10 years: Inconsistencies, mistakes, and new proposals.
    Ann Anat 2018 Jun 6. Epub 2018 Jun 6.
    Centre of Scientific Information, Third Faculty of Medicine, Charles University, Prague, Czech Republic; Institute of Information Studies and Librarianship, Faculty of Arts, Charles University, Prague, Czech Republic.
    This article details our experience with the Terminologia Histologica (TH) and its utility in the teaching of histology, cytology, and clinical medicine (e.g., pathology and hematology). Read More

    3D-Printed specimens as a valuable tool in anatomy education: A pilot study.
    Ann Anat 2018 Jun 5. Epub 2018 Jun 5.
    School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University, Bentley, Perth, WA 6102, Australia.
    Three-dimensional (3D) printing is a modern technique of creating 3D-printed models that allows reproduction of human structures from MRI and CT scans via fusion of multiple layers of resin materials. To assess feasibility of this innovative resource as anatomy educational tool, we conducted a preliminary study on Curtin University undergraduate students to investigate the use of 3D models for anatomy learning as a main goal, to assess the effectiveness of different specimen types during the sessions and personally preferred anatomy learning tools among students as secondary aim. The study consisted of a pre-test, exposure to test (anatomical test) and post-test survey. Read More

    The mechanical properties of fresh versus fresh-frozen and preserved (Thiel and formalin) long head of biceps tendons: a cadaveric investigation.
    Ann Anat 2018 Jun 4. Epub 2018 Jun 4.
    Valiant/Houston Methodist Group, United Arab Emirates.
    Human cadaveric specimens commonly serve as mechanical models and as biological tissue donors in basic biomechanical research. Although these models are used to explain both in vitro and in vivo behavior, the question still remains whether the specimens employed reflect the normal in vivo situation. The mechanical properties of fresh-frozen or preserved cadavers may differ, and whether they can be used to reliably investigate pathology could be debated. Read More

    Neurotrophins and Trk receptors in the developing and adult ovary of Coturnix coturnix japonica.
    Ann Anat 2018 May 26;219:35-43. Epub 2018 May 26.
    Dpt. Veterinary Medicine and Animal Productions, University of Naples Federico II, via F. Delpino 1, 80137 Naples, Italy.
    NGF, BDNF, NT-3 and their specific receptors TrkA, TrkB and TrkC are known to be involved in the development and maintenance of vertebrates' nervous system. However, these molecules play a role also in non-neuronal tissue, such as in the reproductive system. In this study we investigated the presence and localization of neurotrophins and Trk receptors to unravel their potential role in the developing and adult ovary of Japanese quail, a model species well suited for reproduction studies. Read More

    Key molecules in lymphatic development, function, and identification.
    Ann Anat 2018 May 26;219:25-34. Epub 2018 May 26.
    Translational Cancer Biology Research Program, University of Helsinki, Finland; Wihuri Research Institute, Biomedicum Helsinki, Finland. Electronic address:
    While both blood and lymphatic vessels transport fluids and thus share many similarities, they also show functional and structural differences, which can be used to differentiate them. Specific visualization of lymphatic vessels has historically been and still is a pivot point in lymphatic research. Many of the proteins that are investigated by molecular biologists in lymphatic research have been defined as marker molecules, i. Read More

    The development of human digital Meissner's and Pacinian corpuscles.
    Ann Anat 2018 May 26;219:8-24. Epub 2018 May 26.
    Departamento de Morfología y Biología Celular, Grupo SINPOS, Universidad de Oviedo, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco, Chile. Electronic address:
    Meissner's and Pacinian corpuscles are cutaneous mechanoreceptors responsible for different modalities of touch. The development of these sensory formations in humans is poorly known, especially regarding the acquisition of the typical immunohistochemical profile related to their full functional maturity. Here we used a panel of antibodies (to specifically label the main corpuscular components: axon, Schwann-related cells and endoneurial-perineurial-related cells) to investigate the development of digital Meissner's and Pacinian corpuscles in a representative sample covering from 11 weeks of estimated gestational age (wega) to adulthood. Read More

    Optical coherence tomography assessment of gingival epithelium inflammatory status in periodontal - Systemic affected patients.
    Ann Anat 2018 May 25;219:51-56. Epub 2018 May 25.
    Department of Gastroenterelogy, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, No. 2 "Petru Rares" Street, Craiova, Romania.
    Introduction: Optical coherence tomography (OCT) is an imaging tool used in various medical fields (ophthalmology, dermatology), which allows the observation of morphological particularities on the surface of tissues or internal constructive details of about 2-3mms in depth. In periodontology, it has been used as an experimental tool for periodontal pocket analysis (depth, calculus deposits) but not for the assessment of periodontal inflammation in the gingival tissues, which has been the subject of our in-vitro study.

    Material And Method: Gingival samples were collected from three types of patients: patients with periodontal disease; patients with periodontal disease and a systemic comorbidity; periodontal and systemic healthy patients. Read More

    Corrigendum to "A new procedure for processing extracted teeth for immediate grafting in post-extraction sockets. An experimental study in American Fox Hound dogs" [Ann. Anat. 217 (2018) 14-23].
    Ann Anat 2018 Jul 10;218:213. Epub 2018 May 10.
    Biotechnology at the Catholic University of Murcia, Murcia, Spain; Universidad Católica San Antonio de Murcia, Murcia, Spain; Catholic University of Uruguay, Montevideo, Uruguay.

    Anatomical study of the first dorsal extensor compartment for the treatment of de Quervain's disease.
    Ann Anat 2018 Jul 7;218:250-255. Epub 2018 May 7.
    Department of Plastic and Reconstructive Surgery, Dongguk University Medical Center, GoYang, South Korea. Electronic address:
    Introduction: Anatomical variations of the first dorsal extensor compartment (1st EC) are commonly noted.

    Materials And Methods: Forty cadaver hands were dissected to define the 1st EC. Through the gross findings, we classified the contents according to the presence of septation, subcompartment, and variation of tendons. Read More

    Immunolocalization of Orexin A and its receptors in the different structures of the porcine ovary.
    Ann Anat 2018 Jul 5;218:214-226. Epub 2018 May 5.
    Dept. of Veterinary Science, University of Parma, Via del Taglio 10, Parma 43126, Italy.
    Orexins are neuropeptides with pleiotropic functions, involved in the coordination of multiple versatile physiological processes, in particular related to food intake and several aspects of the reproductive process. Their actions are carried out through the bond with the related Orexin 1 (OXR1) and Orexin 2 (OXR2) G-protein-coupled receptors. Studies on the expression of the orexinergic system in the female genital organs are scarce and limited to preovulatory gametogenic follicles and corpora lutea isolated from the rest of the ovary. Read More

    Probiotic supplementation affects the glycan composition of mucins secreted by Brunner's glands of the pig duodenum.
    Ann Anat 2018 Jul 3;218:236-242. Epub 2018 May 3.
    Section of Veterinary Clinics and Animal Productions, Department of Emergency and Organ Transplantation (DETO), University of Bari Aldo Moro, S.P. Casamassima Km 3, 70010 Valenzano, Bari, Italy. Electronic address:
    The effect of a dietary probiotic blend on the carbohydrate composition of mucins secreted by the Brunner's glands in the duodenum of growing-finishing pigs was investigated by means of conventional (periodic acid-Schiff, Alcian Blue pH 2.5, high iron diamine staining) and lectin (15 lectins) histochemistry. Pigs were assigned to two dietary treatments: a control basal diet without the probiotic blend (No-Pro) and a test diet that included the probiotic blend (Pro). Read More

    The existence of labial SMAS - Anatomical, imaging and histological study.
    Ann Anat 2018 Jul 3;218:271-275. Epub 2018 May 3.
    Department of Morpho-Functional Sciences I, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania. Electronic address:
    Cutaneous insertion of the facial mimic muscles concerns, at different levels, the superficial fascia of that region. A superficial musculoaponeurotic system is described at face level that facilitates skin insertion of the facial expression muscles through the superficial fascia that acquires particular functional aspects in each region of the face. The existence of a musculofascial system is seen controversial among anatomists, which is why the purpose of this study is to establish its existence at the oral region. Read More

    Normal microscopic anatomy of equine body and limb skin: A morphological and immunohistochemical study.
    Ann Anat 2018 Jul 3;218:205-212. Epub 2018 May 3.
    Department of Veterinary Sciences, University of Pisa, viale delle Piagge 2, 56124 Pisa, Italy. Electronic address:
    Introduction: Information on microscopic anatomy of equine skin is sparse. In horses, limb wounds often become chronic and/or non-healing whereas body wounds heal normally. These dissimilarities in healing patterns might be a product of different phenotypic characteristics of body and limb skin. Read More

    Impact of obesity and aging on crestal alveolar bone height in mice.
    Ann Anat 2018 Jul 4;218:227-235. Epub 2018 May 4.
    Department of Periodontology and Operative Dentistry, University Medical Center, University of Mainz, Augustusplatz 2, 55131 Mainz, Germany. Electronic address:
    Obesity and aging are associated with periodontitis, which represents a chronic inflammatory disease of the tooth-supporting tissues, i.e. the periodontium. Read More

    Micro-anatomical structure of the first spine of the dorsal fin of Atlantic bluefin tuna, Thunnus thynnus (Osteichthyes: Scombridae).
    Ann Anat 2018 May 3;219:1-7. Epub 2018 May 3.
    Department of Emergency and Organ Transplantation, Section of Veterinary Clinics and Animal Production, University of Bari Aldo Moro, Valenzano, Bari, Italy. Electronic address:
    The first spine of the first dorsal fin (FS) of the Atlantic bluefin tuna (ABFT), Thunnus thynnus, is customarily used in age determination research because its transverse sections display well-defined growth marks. In this paper the FS structure was studied to explain its known dramatic age- and season-related morphological modifications, which are evidently caused by bone remodeling. Cross sections of samples from six adult ABFT were in part decalcified to be stained with histological, histochemical and immunohistochemical methods, and in part embedded in methyl-methacrylate to be either observed under a linear polarized light or microradiographed. Read More

    Development of the long head of the biceps brachial tendon: A possible explanation of the anatomical variations.
    Ann Anat 2018 Jul 3;218:243-249. Epub 2018 May 3.
    Department of Human Anatomy and Embryology, Faculty of Medicine, Complutense University of Madrid (CUM), Madrid, Spain.
    The anatomical variations of the proximal portion of the long head of the biceps brachii tendon (LHBT) are rarely observed in clinical practice. However, an increase in the rate of shoulder arthroscopic surgery has led to an increase in the observation of anatomical variations of this region. The aim of this work was to analyze the development of the LHBT in 23 human embryos ranging from the 6th to 8th weeks of development. Read More

    Mesenteric organ lymphatics and inflammatory bowel disease.
    Ann Anat 2018 Jul 30;218:199-204. Epub 2018 Apr 30.
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing, 210002 PR China.
    Inflammatory bowel disease (IBD) is a complex gastrointestinal disorder and its etiology is unclear yet. Current theory in IBD is focused on genetics, immunity and intestinal microbes. Emerging clinical evidence and experimental results suggest that morphologic abnormalities and dysfunction of mesenteric lymphatics may have potential roles in the pathogenesis and disease course of IBD. Read More

    Neuromast hair cells retain the capacity of regeneration during heavy metal exposure.
    Ann Anat 2018 Jul 30;218:183-189. Epub 2018 Apr 30.
    Department of Veterinary Sciences, University of Messina, Zebrafish Neuromorphology Lab, Italy.
    The neuromast is the morphological unit of the lateral line of fishes and is composed of a cluster of central sensory cells (hair cells) surrounded by support and mantle cells. Heavy metals exposure leads to disruption of hair cells within the neuromast. It is well known that the zebrafish has the ability to regenerate the hair cells after damage caused by toxicants. Read More

    Pitx2 and nodal as conserved early markers of the anterior-posterior axis in the rabbit embryo.
    Ann Anat 2018 Jul 26;218:256-264. Epub 2018 Apr 26.
    Institute of Anatomy and Embryology, Universitätsmedizin Göttingen, Germany. Electronic address:
    Attaining molecular and morphological axial polarity during gastrulation is a fundamental early requirement for normal development of the embryo. In mammals, the first morphological sign of the anterior-posterior axis appears anteriorly in the form of the anterior marginal crescent (or anterior visceral endoderm) while in the avian the first such sign is the Koller's sickle at the posterior pole of the embryonic disc. Despite this inverse mode of axis formation many genes and molecular pathways involved in various steps of this process seem to be evolutionarily conserved amongst amniotes, the nodal gene being a well-known example with its functional involvement prior and during gastrulation. Read More

    Decreased microglial numbers in Vav1-Cre:dicer knock-out mice suggest a second source of microglia beyond yolk sac macrophages.
    Ann Anat 2018 Jul 26;218:190-198. Epub 2018 Apr 26.
    Institute of Anatomy, Leipzig University, Leipzig, Germany. Electronic address:
    Microglia represent the resident macrophages of the central nervous system (CNS). While it is clear that microglia recruitment is established by differentiation of primitive yolk sac (YS) macrophages and consecutive invasion of the brain, starting around E8 in rodents (Ginhoux et al., 2010), more recent studies suggest that a non-YS contribution to the microglia population should not entirely be dismissed (Swinnen et al. Read More

    Plasma of argon enhances the adhesion of murine osteoblasts on different graft materials.
    Ann Anat 2018 Jul 26;218:265-270. Epub 2018 Apr 26.
    CIR Dental School, Department of Surgical Sciences UNITO, via Nizza 230, 10126 Turin, Italy.
    Objective: Plasma of argon treatment was demonstrated to increase material surface energy leading to stronger and faster interaction with cells. The aim of the present in vitro study was to test the effect of plasma treatment on different graft materials.

    Materials And Methods: Synthetic hydroxyapatite (Mg-HA), biphasic calcium phosphate (BCP), cancellous and cortical xenogeneic bone matrices (CaBM, CoBM) were used representing commonly used classes of bone substitute materials. Read More

    The telopode- and filopode-projecting heterogeneous stromal cells of the human sclera niche.
    Ann Anat 2018 Jul 22;218:129-140. Epub 2018 Apr 22.
    Division of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; MEDCENTER - Center of Excellence in Laboratory Medicine and Pathology, Bucharest, Romania. Electronic address:
    Telocytes (TCs) are stromal cells defined by the presence of long and slender prolongations (telopodes). They are a biologically and functionally heterogeneous population that has not been previously investigated in the sclera. The purpose of this study is to investigate the presence and characteristics of scleral telocytes through a combined immunohistochemical and transmission electron microscopy (TEM) study using samples from ten adult patients. Read More

    Stromal cells/telocytes and endothelial progenitors in the perivascular niches of the trigeminal ganglion.
    Ann Anat 2018 Jul 20;218:141-155. Epub 2018 Apr 20.
    Division of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
    Stromal cells/telocytes (SCs/TCs) were recently described in the human adult trigeminal ganglion (TG). As some markers are equally expressed in SCs/TCs and endothelial cells, we hypothesized that a subset of the TG SCs/TCs is in fact represented by endothelial progenitor cells of a myelomonocytic origin. This study aimed to evaluate whether the interstitial cells of the human adult TG correlate with the myelomonocytic lineage. Read More

    Pulmonary lymphatic vessel morphology: a review.
    Ann Anat 2018 Jul 19;218:110-117. Epub 2018 Apr 19.
    ILD Unit Royal Brompton Hpospital,Sydney Street SW3 6LR, London, UK. Electronic address:
    Our understanding of lymphatic vessels has been advanced by the recent identification of relatively specific lymphatic endothelium markers, including Prox-1, VEGFR3, podoplanin and LYVE-1. The use of lymphatic markers has led to the observation that, contrary to previous assumptions, human lymphatic vessels extend deep inside the pulmonary lobule, either in association with bronchioles, intralobular arterioles or small pulmonary veins. Pulmonary lymphatic vessels may thus be classified into pleural, interlobular (in interlobular septa) and intralobular. Read More

    Effectiveness evaluation of digital virtual simulation application in teaching of gross anatomy.
    Ann Anat 2018 Jul 18;218:276-282. Epub 2018 Apr 18.
    Eight-Year Program of Clinical Medicine in Class 2013, Xiangya School of Medicine, Central South University, Changsha (Hunan) 410013, China.
    Introduction: Digital virtual simulation (DVS) is increasingly used to supplement the teaching of anatomy. DVS can provide the students with three-dimensional (3D) stereoscopic images and precise structures in anatomy teaching. We investigated the effects of digital virtual simulation (DVS) application in gross anatomy teaching. Read More

    Enhancement of peri-implant bone osteogenic activity induced by a peptidomimetic functionalization of titanium.
    Ann Anat 2018 Jul 19;218:165-174. Epub 2018 Apr 19.
    Dept. of Veterinary Sciences.
    Osteoblast cell adhesion to the extracellular matrix is established through two main pathways: one is mediated by the binding between integrin and a minimal adhesion sequence (RGD) on the extracellular protein, the other is based on the interactions between transmembrane proteoglycans and heparin-binding sequences found in many matrix proteins. The aim of this study is the evaluation in an in vivo endosseous implant model of the early osteogenic response of the peri-implant bone to a biomimetic titanium surface functionalized with the retro-inverso 2DHVP peptide, an analogue of Vitronectin heparin binding site. The experimental plan is based on a bilateral study design of Control and 2DHVP implants inserted respectively in the right and left femur distal metaphysis of adult male Wistar rats (n=16) weighing about 300grams and evaluated after 15days. Read More

    Localization of cholecystokinin in the zebrafish retina from larval to adult stage.
    Ann Anat 2018 Jul 19;218:175-181. Epub 2018 Apr 19.
    Department of Veterinary Sciences, University of Messina, Zebrafish Neuromorphology Lab. Messina, Italy.
    The peptide hormone cholecistokinin (CCK) plays a key role in the central and peripheral nervous system. It is known to be involved in the digestive physiology and in the regulation of food intake. Moreover, the CCK expression has also been detected in the retina of different vertebrates, including fish, although its biological activity in this tissue remains to be elucidated. Read More

    What podoplanin tells us about cells with telopodes.
    Ann Anat 2018 Jul 18;218:124-128. Epub 2018 Apr 18.
    Division of Pathologic Anatomy, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; MEDCENTER - Center of Excellence in Laboratory Medicine and Pathology, Romania.
    Telocytes (TCs) are stromal cells with telopodes, which represent long, thin, moniliform cell processes; however, this morphological feature alone is insufficient to define a cell type. Specific markers of lymphatic endothelial cells (LECs), such as Prox-1, podoplanin (D2-40) or LYVE-1, are not usually tested in TCs. We thus aimed at performing a study in light microscopy to evaluate whether or not LECs could be mistaken for TCs. Read More

    Anatomy learning from prosected cadaveric specimens versus three-dimensional software: A comparative study of upper limb anatomy.
    Ann Anat 2018 Jul 15;218:156-164. Epub 2018 Apr 15.
    Department of Anatomy, Faculty of Medicine, University of Thessaly, 41110, Larissa, Greece. Electronic address:
    Introduction: Modern, three-dimensional (3D) anatomy software is a promising teaching method, though few studies examine its effectiveness on upper limb and musculoskeletal anatomy learning. The purpose of this study is to investigate which method is associated with a better outcome, as assessed by students' performance on examinations, when comparing learning with prosections to the use of 3D software.

    Materials And Methods: Two groups of undergraduate, first-year medical students without previous knowledge of anatomy were compared. Read More

    Molecular phenotypes of the human kidney: Myoid stromal cells/telocytes and myoepithelial cells.
    Ann Anat 2018 Jul 13;218:95-104. Epub 2018 Apr 13.
    Division of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
    The connective stromal and epithelial compartments of the kidney have regenerative potential and phenotypic flexibility. A few studies have shown that cells appertaining to both compartments can exhibit myoid phenotypes. The purpose of our study was to investigate the myoid pattern of kidney and its association with the kidney niches containing stromal cells/telocytes (SC/TCs). Read More

    Telocyte-like cells containing Weibel-Palade bodies in rat lamina fusca.
    Ann Anat 2018 Jul 12;218:88-94. Epub 2018 Apr 12.
    Division of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
    Telocytes (TCs) are cells with long, thin and moniliform processes called telopodes. These cells have been found in numerous tissues, including the eye choroid and sclera. Lamina fusca (LF), an anatomical structure located at the sclera-choroid junction, has outer fibroblastic lamellae containing cells with long telopodes. Read More

    Cardiac telocytes. From basic science to cardiac diseases. I. Atrial fibrillation.
    Ann Anat 2018 Jul 12;218:83-87. Epub 2018 Apr 12.
    Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
    Introduction: Atrial fibrillation (AF) is nowadays considered to be one of the most important causes of heart failure, stroke, cognitive decline, vascular dementia, sudden death and overall cardiovascular morbidity. Recently were published a few articles suggesting a possible involvement of telocytes in the development of atrial fibrillation. The purpose of this article is to analyze the results obtained in the field systematically, and to see if there is enough data to support a possible involvement of telocytes in arrhythmogenesis. Read More

    The telocytes/myofibroblasts 3-D network forms a stretch receptor in the human bladder mucosa. Is this structure involved in the detrusor overactive diseases?
    Ann Anat 2018 Jul 11;218:118-123. Epub 2018 Apr 11.
    Department of Experimental and Clinical Medicine, Research Unit of Histology and Embryology, University of Florence, Florence, Italy.
    Several connective tissue cells are present in the human bladder wall; among them, the myofibroblasts (MyF) and the so-called interstitial cells (IC) are a matter of investigation either by basic researchers or clinicians. The interest derives from the possibility that these two cell types could regulate the organ function forming a special sensory system in the bladder mucosa. Whereas attention for the myofibroblasts was mainly focused on understanding their role, the so-called IC are debatable starting from their nomenclature. Read More

    Erratum to "Neurotrophins and specific receptors in the oviduct tracts of Japanese quail (Coturnix coturnix japonica)" [AANAT 210C (2017) 112-120].
    Ann Anat 2018 May;217:142
    Dpt. Normal and Pathological Morphology, University of Agricultural Science and Veterinary Medicine, 'Ion Ionescu de la Brad' Iasi Faculty of Veterinary Medicine, 8 M. Sadoveanu Alley, 700489 Iasi, Romania.

    Three-dimensional CAD/CAM imaging of the maxillary sinus in ageing process.
    Ann Anat 2018 Jul 5;218:69-82. Epub 2018 Apr 5.
    Department of Anatomy, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Srobarova 2, 041 80 Kosice, Slovak Republic. Electronic address:
    Objectives: During the physiological ageing process atrophy of the alveolar bone appears in vertical direction. This bone resorption causes pushing the limits of the maxillary sinus at the expense of a degraded bone. The sinus volume increases due to the facial development in children and adolescents or during the ageing process due to the loss of teeth and bone mass. Read More

    The deep lymphatic anatomy of the hand.
    Ann Anat 2018 Jul 3;218:105-109. Epub 2018 Apr 3.
    Department of Radiology, Xuzhou Oriental People's Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, PR China.
    Background: The deep lymphatic anatomy of the hand still remains the least described in medical literature.

    Methods: Eight hands were harvested from four nonembalmed human cadavers amputated above the wrist. A small amount of 6% hydrogen peroxide was employed to detect the lymphatic vessels around the superficial and deep palmar vascular arches, in webs from the index to little fingers, the thenar and hypothenar areas. Read More

    The influence of temporomandibular joint movement parameters on dental morphology.
    Ann Anat 2018 Jul 3;218:49-58. Epub 2018 Apr 3.
    Oral and Maxillofacial Surgeon Dental Techniques Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. Electronic address:
    Association between tooth morphology, occlusal relations and mandibular condyle/glenoid fossa morphology is still a controversial issue in dentistry. The aim of the present study was to examine the influence of three important articular parameters on the dental morphology and the crown volume, quantifying the variation for each tooth group: incisor, canine, premolar and molar.

    Materials And Methods: All maxillary teeth from a set of basic study models were prepared for zirconia single crowns. Read More

    Salivary biomarkers of inflammation in systemic lupus erythematosus.
    Ann Anat 2018 Apr 2. Epub 2018 Apr 2.
    Carol Davila University of Medicine and Pharmacy Bucharest, 8 Eroii Sanitari Blvd, 050474, Bucharest, Romania.
    Saliva is currently used as a reliable diagnostic fluid in a wide range of local and systemic diseases. However, the link between salivary diagnosis and the inflammatory process in autoimmune diseases has not yet been explored. The aim of our study is to assess possible correlations between salivary inflammatory markers and systemic lupus erythematosus (SLE). Read More

    William Hunter and lymphatics.
    Ann Anat 2018 Jul 3;218:40-48. Epub 2018 Apr 3.
    Anatomy Facility, School of Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
    William Hunter along with his brother, John, and their colleagues William Hewson, William Cruikshank and John Sheldon made a large contribution to understanding of lymphatic vessels. Hewson, Cruikshank and Sheldon all carried out mercury injections and made much progress in mapping the distribution of lymphatics in the human body. William Hunter appreciated that lymphatics absorbed fluid from the tissues of the body and that lacteals of the intestine and lymphatics are similar structures. Read More

    Craniofacial structure alterations of foetuses from folic acid deficient pregnant mice.
    Ann Anat 2018 Jul 28;218:59-68. Epub 2018 Mar 28.
    Departamento de Anatomía y Embriología Humanas y Veterinarias, Facultad de Medicina, Universidad Complutense de Madrid, Spain. Electronic address:
    Introduction: Craniofacial development in mammals is a complex process that involves a coordinated series of molecular and morphogenetic events. Folic acid (FA) deficiency has historically been associated with congenital spinal cord malformations, but the effect that a maternal diet deficient in FA has on the development of other structures has been poorly explored. In the present study, the objective was to describe and quantify the alterations of craniofacial structures presented in mouse foetuses from dams fed a FA deficient (FAD) diet compared with controls that were given a regular maternal diet. Read More

    Structural differences in enamel and dentin in human, bovine, porcine, and ovine teeth.
    Ann Anat 2018 Jul 28;218:7-17. Epub 2018 Mar 28.
    Servei de Recursos Científics i Técnics, Universitat Rovira i Virgili, Avda, Països Catalans 26, 43007 Tarragona, Spain.
    Background: The aim was to study differences between crystalline nanostructures from the enamel and dentin of human, bovine, porcine, and ovine species.

    Methods: Dentine and enamel fragments extracted from sound human, bovine, porcine and ovine incisors and molars were mechanically ground up to a final particle size of <100μm. Samples were analyzed using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and differential scanning calorimetry (DSC). Read More

    Applications of inflammation-derived gingival stem cells for testing the biocompatibility of dental restorative biomaterials.
    Ann Anat 2018 Jul 28;218:28-39. Epub 2018 Mar 28.
    Laboratory of Radiotherapy, Tumor and Radiobiology, Prof. Dr. Ion Chiricuţă Oncology Institute, 34-36 Republicii St., 400015 Cluj-Napoca, Romania.
    Background: Normal or inflamed gingival tissues are regarded as a source of mesenchymal stem cells (MSCs) abundant and easily accessible through minimally invasive dental procedures. Due to the proximity of dental resin composites to gingival tissues and to the possible local cytotoxic effect of the eluted components, gingiva-derived MSCs could be used to investigate the biocompatibility of dental biomaterials.

    Purpose: The present research aimed to isolate (MSCs) from inflamed and normal gingiva, to fully characterize them and to observe their behavior in relation with some commercial resin composite materials and one experimental material. Read More

    Cardiac telocytes. From basic science to cardiac diseases. II. Acute myocardial infarction.
    Ann Anat 2018 Jul 28;218:18-27. Epub 2018 Mar 28.
    Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
    Introduction: The purpose of this study was to evaluate the scientific evidence regarding a potential role of telocytes in myocardial infarction.

    Materials And Methods: To this purpose, we performed a systematic review of relevant scientific literature, indexed in PubMed, Web of Science, and Scopus.

    Results And Discussions: We found six articles containing relevant studies aimed at liking myocardial infarction and telocytes. Read More

    Morphological analysis and three-dimensional reconstruction of the SMAS surrounding the nasolabial fold.
    Ann Anat 2018 May 26;217:111-117. Epub 2018 Mar 26.
    Department of Biological and Material Sciences in Dentistry, Faculty of Health, Witten/Herdecke University, Witten, Germany. Electronic address:
    Background: The superficial musculoaponeurotic system (SMAS), a structure that has been discussed with some controversy, has a complex morphological architecture.

    Material And Methods: Histological analysis was performed on tissue blocks of the nasolabial fold (NLF) collected postmortem from formalin-fixed bodies of one male and one female donor. Serial histological sections were made, stained and digitized. Read More

    Proximal and distal alignment of normal canine femurs: A morphometric analysis.
    Ann Anat 2018 May 19;217:125-128. Epub 2018 Mar 19.
    Istanbul University, Faculty of Veterinary Medicine, Department of Anatomy, Istanbul, Turkey.
    Many researchers are interested in femoral conformation because most orthopaedic problems of the long bones occur in the femur and its joints. The neck-shaft (NSA) and the anteversion (AVA) angles are good predictors for understanding the orientation of the proximal end of the femur. The varus (aLDFA) and procurvatum (CDFA) angles have also been used to understand the orientation of the distal end of the femur. Read More

    Elongated styloid process in patients with temporomandibular disorders - Is there a link?
    Ann Anat 2018 May 17;217:118-124. Epub 2018 Mar 17.
    Department of Prosthodontics, University Medical Center Goettingen, Robert-Koch-Straße 40, D-37075 Goettingen, Germany.
    Background: Elongated styloid processes may display clinical signs that can easily be confused with symptoms associated with temporomandibular disorders (TMD). Thus, the present study aimed to investigate alterations of the styloid process in patients with TMD.

    Methods: Temporomandibular joint (TMJ) X-ray images of 192 patients with RDC/TMD diagnoses were examined retrospectively. Read More

    Gender as an underestimated factor in mental health of medical students.
    Ann Anat 2018 Jul 15;218:1-6. Epub 2018 Mar 15.
    Department of Anatomy II, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany. Electronic address:
    Background: In Germany, currently two out of three medical students are female. Several studies corroborate that medical students show a significantly higher prevalence of stress-related mental disorders than the population in general.

    Aims: We aimed to evaluate, if gender has an influence on the distribution of mental stress parameters and learning style among male and female medical students. Read More

    Advances in cryo-electron tomography for biology and medicine.
    Ann Anat 2018 May 8;217:82-96. Epub 2018 Mar 8.
    Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands. Electronic address:
    Cryo-electron tomography (CET) utilizes a combination of specimen cryo-fixation and multi-angle electron microscopy imaging to produce three-dimensional (3D) volume reconstructions of native-state macromolecular and subcellular biological structures with nanometer-scale resolution. In recent years, cryo-electron microscopy (cryoEM) has experienced a dramatic increase in the attainable resolution of 3D reconstructions, resulting from technical improvements of electron microscopes, improved detector sensitivity, the implementation of phase plates, automated data acquisition schemes, and improved image reconstruction software and hardware. These developments also greatly increased the usability and applicability of CET as a diagnostic and research tool, which is now enabling structural biologists to determine the structure of proteins in their native cellular environment to sub-nanometer resolution. Read More

    Effects of in-office bleaching on human enamel and dentin. Morphological and mineral changes.
    Ann Anat 2018 May 6;217:97-102. Epub 2018 Mar 6.
    Department of Stomatology, Universitat de València, Clínica Odontológica, C. Gascó Oliag, 1, 46010 Valencia, Spain.
    Background: The effects of HP-based products upon dental enamel and dentin are inconclusive.

    Aim: To evaluate changes in micromorphology and composition of calcium (Ca) and phosphate (P) in enamel and dentin after the application of 37.5% hydrogen peroxide (HP) and 35% carbamide peroxide (CP) METHODS: Crowns of 20 human teeth were divided in two halves. Read More

    1 OF 41