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    1972 results match your criteria Annals of Anatomy Anatomischer Anzeiger [Journal]

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    Anatomists' perceptions of the skills and attributes required of newly-recruited medical students.
    Ann Anat 2018 Feb 11. Epub 2018 Feb 11.
    Formerly of St George's University, Grenada, West Indies.
    Background And Purpose: Admission procedures for recruiting students to medical school vary considerably across the world. Notwithstanding such variability, it is important to know what skills and attributes are required of the students by their teachers on entering medical school.

    Procedures: Anatomists are often the teachers who first meet the students as they enter medical school and this report analyses, by means of a questionnaire, the putative skills required of their medical students by anatomists from the U. Read More

    Reversal of drug-induced gingival overgrowth by UV-mediated apoptosis of gingival fibroblasts - an in vitro study.
    Ann Anat 2018 Feb 7;217:7-11. Epub 2018 Feb 7.
    Southern Illinois University School of Dental Medicine, Alton, IL 62002, USA. Electronic address:
    Gingival overgrowth (GO) is an undesirable result of certain drugs like Cyclosporine A (CsA). Histopathology of GO shows hyperplasia of gingival epithelium, expansion of connective tissue with increased collagen, or a combination. Factors such as age, gender, oral hygiene, duration, and dosage also influence onset and severity of GO. Read More

    Review: Limb regeneration in humans: Dream or reality?
    Ann Anat 2018 Feb 3;217:1-6. Epub 2018 Feb 3.
    Comparative Histolab, Padova, Italy; Department of Biology, University of Bologna, Italy. Electronic address:
    Appendage regeneration occurs by a sequence of events resembling those that take place during development in the embryo. This requires embryonic conditions such as hydration and hyaluronate content where Wnt and other signaling pathways, together with non- coding RNAs, can be re-expressed. These conditions among vertebrates are fully met only in amputated limbs of amphibians, likely because they are neotenic and maintain larval characteristics, including immaturity of their immune system and permanence of numerous stem cells. Read More

    Long-term estradiol-17β exposure decreases the cholinergic innervation pattern of the pig ovary.
    Ann Anat 2018 Jan 2;216:135-141. Epub 2018 Jan 2.
    Division of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 14 Str., 11-041 Olsztyn, Poland.
    Elevated levels of endogenous estrogens in the course of pathological states of ovaries, as well as xenoestrogens, may lead to hyperestrogenism. It has previously been demonstrated that long-term estradiol-17β (E) administration in adult gilts affected the population of sympathetic intraovarian nerve fibers. The aim of this study has been to determine the effect of long-term Eexposure on the cholinergic innervation pattern of porcine ovaries. Read More

    Induced post-traumatic apexification: 20 year follow-up and morphological study after new fracture.
    Ann Anat 2018 Jan 1;216:120-124. Epub 2018 Jan 1.
    Department of Stomatology, Universitat de València (Spain) Clínica Odontológica, Calle Gascó Oliag, 1, 46010 Valencia, Spain. Electronic address:
    Apexification is an endodontic technique used in immature necrotic teeth, the primary goal of which is to induce a calcified barrier in roots with open apices and to promote the continuation of apical root development. A 7-year-old patient with a coronal fracture in a maxillary central incisor was treated with an apexification technique using calcium hydroxide. The apical closure was obtained after one year, then a permanent root canal filling was performed. Read More

    Biomolecules in the treatment of lichen planus refractory to corticosteroid therapy: Clinical and histopathological assessment.
    Ann Anat 2018 Jan 1;216:159-163. Epub 2018 Jan 1.
    University Institute for Regenerative Medicine and Oral Implantology-UIRMI (UPV/EHU-Fundación Eduardo Anitua), Vitoria, Spain; BTI Biotechnology Institute, Vitoria, Spain. Electronic address:
    Background: Local deficit of several biomolecules have been described in oral lichen planus (OLP). Such a deficit impairs cellular functions and cell-matrix communication.

    Purpose: Assess the efficacy of the local application of autologous biomolecules in the treatment of erosive OLP. Read More

    Fetal sigmoid colon mesentery - In relevance in fetal ultrasound application. A pilot study.
    Ann Anat 2017 Dec 29;216:152-158. Epub 2017 Dec 29.
    Department of Human Morphology and Embryology, Division of Anatomy, Wroclaw Medical University, ul. Chalubinskiego 6a, 50-368 Wroclaw, Poland.
    Introduction: Ultrasound examinations during pregnancy are routine procedures used to detect fetal congenital malformations. Ultrasound monitoring of sigmoid colon mesenterial development could be useful for early detection of subjects at risk of sigmoid colon volvulus.

    Objective: The aim of our paper was to assess the sigmoid colon length, and sigmoid colon mesentery width and height in the late fetal period, and, using the results, to estimate the surface area of the mesocolon (in mm) in living fetuses. Read More

    Lipopolysaccharide induces tumor necrosis factor receptor-1 independent relocation of lymphocytes from the red pulp of the mouse spleen.
    Ann Anat 2017 Dec 28;216:125-134. Epub 2017 Dec 28.
    Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Electronic address:
    It is well known that bacterial lipopolysaccharide (LPS) induces migration of several cellular populations within the spleen. However, there are no data about the impact of LPS on B and T lymphocytes present in the red pulp. Therefore, we used an experimental model in which we tested the effects of intravenously injected LPS on the molecular, cellular and structural changes of the spleen, with special reference to the red pulp lymphocytes. Read More

    Early molecular response and microanatomical changes in the masseter muscle and mandibular head after botulinum toxin intervention in adult mice.
    Ann Anat 2017 Dec 28;216:112-119. Epub 2017 Dec 28.
    Institute for Research in Dental Sciences, Faculty of Dentistry, Universidad de Chile, Chile. Electronic address:
    Background: Masseter muscle paralysis induced by botulinum toxin type A (BoNTA) evokes subchondral bone loss in mandibular heads of adult rats and growing mice after 4 weeks. However, the primary cellular and molecular events leading to altered bone remodeling remain unexplored. Thus, the aim of the current work has been to assess the molecular response that precedes the early microanatomical changes in the masseter muscle and subchondral bone of the mandibular head in adult mice after BoNTA intervention. Read More

    Periostin, dentin matrix protein 1 and P2rx7 ion channel in human teeth and periodontal ligament.
    Ann Anat 2017 Dec 28;216:103-111. Epub 2017 Dec 28.
    Instituto Asturiano de Odontología, Oviedo, Spain; Departamento de Cirugía y Especialidades Médico-Quirúrgicas, Universidad de Oviedo, Spain.
    The periostin is a matricellular protein present in the human periodontal ligament and human dental pulp-derived cells lines, that up-regulates the in vitro expression of some genes involved in the dentin mineralization, such as dentin matrix protein 1 and P2x7-ion channel receptor. Here we investigated the distribution of periostin in human teeth and periodontal ligaments, mapping in parallel the localization of dentin matrix protein 1 and P2x7-ion channel receptor to establish whether or not they are expressed in the same places as periostin. The periodontal ligament and the subodontoblastic layer of the dental pulp displayed strong periostin immunoreactivity, whereas dentin matrix protein 1 was detected in the periodontal ligament co-localized with periostin in the vicinity of the cement. Read More

    Effect of ageing on the myosin heavy chain composition of the human sternocleidomastoid muscle.
    Ann Anat 2017 Dec 28;216:95-99. Epub 2017 Dec 28.
    Institute of Anatomy, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
    The myosin heavy chain (MyHC) composition of ageing limb muscles is transformed into a slower phenotype and expresses fast-twitch fibre type atrophy, presumably due to age-related motor unit remodelling and a change in the patterns of physical activity. It is not known if ageing affects the sternocleidomastoid muscle (SCM) in a similar way. The goal of the study was to analyze the MyHC composition and the size of muscle fibres in the ageing SCM by immunohistochemical methods and quantitative analysis and stereology using our own software for morphometry. Read More

    Periodontal materials and cell biology for guided tissue and bone regeneration.
    Ann Anat 2017 Dec 28;216:164-169. Epub 2017 Dec 28.
    Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu, 011061 Bucharest, Romania; Academy of Romanian Scientist, Splaiul Independentei 54, 050094 Bucharest, Romania.
    The present review is intended to find links between periodontal materials of the dentomaxillary apparatus and cell biology at the beginning of a century fraught with various forms of periodontal diseases and needing new treatment strategies. The manuscript has two different parts. The first describes the anatomy of tooth supporting structures, as well as related pathologies. Read More

    Massa adiposa ligamenti falciformis or anterior abdominal fat pad - Its dimension and relation to body weight.
    Ann Anat 2017 Dec 27;216:100-102. Epub 2017 Dec 27.
    Institute of Anatomy and Cell Biology, Saarland University, Kirrberger Strasse, 66424 Homburg/Saar, Germany. Electronic address:
    The anterior abdominal fat pad is associated with the falciform ligament in the upper middle/right abdomen and is frequently seen there in diagnostic imaging. It varies greatly in size and has often been described as an incidental finding in adults and has hitherto rarely been regarded as being illness-relevant. The aim of this study has been to assess whether the dimension of the corpus adiposum may be associated with body mass index. Read More

    Quantification of surfactant proteins in tears of patients suffering from dry eye disease compared to healthy subjects.
    Ann Anat 2017 Dec 24;216:90-94. Epub 2017 Dec 24.
    Department of Anatomy II, Friedrich-Alexander-University Erlangen-Nürnberg, Universitätsstraße 19, 91054 Erlangen, Germany. Electronic address:
    Purpose: To quantify and compare the amounts of surfactant proteins SP-A, SP-B, SP-C and SP-D in the tear fluid collected from patients with dry eye syndrome and from individuals with a healthy ocular surface.

    Methods: Schirmer strips were used to collect tear fluid from both eyes of 241 volunteers (99 men, 142 women; age range: 18-87 years). Dry eye syndrome was diagnosed by ophthalmologists in 125 patients, whereas the healthy control group comprised 116 individuals. Read More

    Carthamus tinctorius L. extract improves hemodynamic and vascular alterations in a rat model of renovascular hypertension through Ang II-ATR-NADPH oxidase pathway.
    Ann Anat 2017 Dec 20;216:82-89. Epub 2017 Dec 20.
    Department of Physiology, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand; Cardiovascular Research Group, Khon Kaen University, 40002, Khon Kaen, Thailand. Electronic address:
    Carthamus tinctorius L. (CT) is widely used in Asian countries as a beverage and in folk medicine. The effects of CT extract on hemodynamics, vascular remodeling, the renin-angiotensin system (RAS) and oxidative stress in the two-kidney, one clip (2K-1C) hypertensive rat model were investigated. Read More

    Human body donation in Thailand: Donors at Khon Kaen University.
    Ann Anat 2017 Dec 20;216:142-151. Epub 2017 Dec 20.
    Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
    Background: Culture, society and spirituality contribute to variability in the characteristics of human body donors and donation programmes worldwide. The donors and the body donation programme at Khon Kaen University, northeast Thailand, reflect all these aspects of Thailand, including the status accorded to the donors and the ceremonial acknowledgement of the donors and their families.

    Methods: Data from the programme records and from surveys of samples of currently registering donors and recently received donor bodies are analysed to define the characteristics of both registering and received donors, including motivation, demography, socio-economic status, health, and use of the bodies. Read More

    Ultrasound assessment of soft tissue augmentation around implants in the aesthetic zone using a connective tissue graft and xenogeneic collagen matrix - 1-year randomised follow-up.
    Ann Anat 2017 Dec 15. Epub 2017 Dec 15.
    Department of Dental Surgery, Silesian Piast Medical University of Wroclaw, Poland.
    Purpose: A comparative, ultrasound evaluation of the thickness of keratinized mucosa (TKT) around implants one year after gingival augmentation (GA) by means of a connective tissue graft (CTG) and the xenogeneic collagen matrix (CMX).

    Materials And Methods: A total of 75 bone level tapered implants (ConelogCamlog) were inserted in 57 patients in the aesthetic area of both jaws. The patients were divided into 3 groups: control group I- without GA; group II- GA 3 months before implantation, and group III- GA 3 months after implantation. Read More

    Effect of different resistance-training protocols on the extracellular matrix of the calcaneal tendon of rats.
    Ann Anat 2017 Dec 8;216:75-81. Epub 2017 Dec 8.
    Department of Structural and Functional Biology, State University of Campinas, Campinas, Brazil.
    The calcaneal tendon extracellular matrix (ECM) is composed of collagen, non-collagenous glycoproteins and proteoglycans, and able to adapt to various biomechanical stimuli. The objective of this study was to analyze the response of different resistance-training protocols, such as hypertrophy, strength and resistance, on the organization of the calcaneal tendon after training. Wistar rats were divided into four groups: untrained (UT), resistance training (RT), hypertrophy training (HT), and strength training (ST). Read More

    Complications in the treatment of mandibular condylar fractures: Surgical versus conservative treatment.
    Ann Anat 2017 Dec 6;216:60-68. Epub 2017 Dec 6.
    Department of Morphological Sciences, School of Medicine, University of Córdoba, Avenida de Menéndez Pidal s/n, 14071 Córdoba, Spain. Electronic address:
    Objectives: In the present article, we aim to review the main intra- and post-operative complications associated with two different therapeutic approaches for treating mandibular condylar fractures: conservative (CTR) and surgical treatment (ORIF, Open Reduction and Internal Fixation).

    Material And Methods: We have carried out a retrospective, meta-analytic, observational study using literature review, covering the period between 2000- September 2017. The data obtained were processed using statistical software SPSS v. Read More

    Morphological features of the anterior talofibular ligament by the number of fiber bundles.
    Ann Anat 2017 Nov 28;216:69-74. Epub 2017 Nov 28.
    Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, Niigata 950-3198, Japan.
    The aims of this study have been to clarify differences in morphological features based on the number of fiber bundles in the anterior talofibular ligament (ATFL), and to investigate the relationship between the ATFL and the calcaneofibular ligament (CFL). This study used 81 legs from 43 cadavers. The ATFL was classified according to differences in the number of fiber bundles as: Type I, with one fiber bundle; Type II-a, with two fiber bundles that were incompletely separated; Type II-b, with two fiber bundles that were completely separated; and Type III, with three fiber bundles. Read More

    Immunolocalization of connective tissue growth factor, transforming growth factor-beta1 and phosphorylated-SMAD2/3 during the postnatal tooth development and formation of junctional epithelium.
    Ann Anat 2017 Nov 22;216:52-59. Epub 2017 Nov 22.
    The Institute of Stomatology, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China; Department of Endodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China. Electronic address:
    Connective tissue growth factor (CTGF) is a downstream mediator of transforming growth factor-beta 1 (TGF-β) and TGF-β-induced CTGF expression is regulated through SMAD pathway. However, there is no literature showing the expression of TGF-β-SMAD2/3-CTGF signaling pathway during postnatal tooth development and the formation of junctional epithelium (JE). Hence, we aimed to analyze the localization of TGF-β, CTGF and phosphorylated SMAD2/3 (p-SMAD2/3) in the developing postnatal rat molars. Read More

    Anatomic characterization of the radial and ulnar nutrient arteries in humans.
    Ann Anat 2017 Nov 21;216:23-28. Epub 2017 Nov 21.
    Department of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan. Electronic address:
    Background: The localization of nutrient foramens has been extensively studied in humans and other vertebrate animals. However, accurate information on the origin and extraosseous course of the nutrient arteries in some types of long tubular bones is lacking. Terminologia Anatomica, the international standard on human anatomic terminology, lists the radial nutrient artery (RNA) and the ulnar nutrient artery (UNA) as branches of the radial and ulnar arteries, respectively. Read More

    Distribution and neurochemistry of porcine urinary bladder-projecting sensory neurons in subdomains of the dorsal root ganglia: A quantitative analysis.
    Ann Anat 2017 Nov 21;216:36-51. Epub 2017 Nov 21.
    Department of Human Physiology, School of Medicine, Collegium Medicicum, University of Warmia and Mazury Olsztyn, Poland.
    The aim of the present study has been to verify the inter- and intraganglionic distribution pattern of porcine urinary bladder-projecting (UBP) neurons localized in the sacral dorsal root ganglia (DRGs). The morphology and chemical phenotype of these cells have also been investigated. These neurons were visualized using the fluorescent tracer Fast Blue (FB) which was injected bilaterally into the urinary bladder wall of five juvenile female pigs. Read More

    Morphological characteristics and variations of the human quadratus plantae muscle.
    Ann Anat 2017 Nov 21;216:9-22. Epub 2017 Nov 21.
    Medical University of Vienna, Center for Anatomy and Cell Biology, Division of Anatomy, Waehringer Strasse 13, 1090 Vienna, Austria. Electronic address:
    The quadratus plantae (QP) is a highly variable structure. A number of partly inexact descriptions of this entity have been provided in textbooks of anatomy. Although several authors have examined the QP, its exact site of origin and type of insertion have hitherto not been specified. Read More

    Dissociation of mono- and co-culture spheroids into single cells for subsequent flow cytometric analysis.
    Ann Anat 2017 Nov 21;216:1-8. Epub 2017 Nov 21.
    Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Building 57, 66421 Homburg, Germany. Electronic address:
    Background: Spheroids are considered to reflect the natural organization of cells better than 2D cell cultures, but their analysis by flow cytometry requires dissociation into single cells.

    Methods: We established protocols for dissociation of mono- and co-culture spheroids consisting of human fibroblasts and human endothelial cells. Cell recovery rate and viability after dissociation were evaluated with hemocytometer and by flow cytometry. Read More

    Periodic acid-Schiff (PAS) reaction and plastination in whole body slices. A novel technique to identify fascial tissue structures.
    Ann Anat 2017 Nov 13;216:29-35. Epub 2017 Nov 13.
    Department of Obstetrics and Gynecology, Women and Children Center, University Hospital Leipzig, Liebigstr. 20a, D-04103 Leipzig, Germany.
    Since collagen rich fascial tissue is often very delicate and difficult to discern on native tissue slices, we have developed a method for staining full-body slices using the periodic acid-Schiff (PAS) reaction with subsequent plastination. Since the PAS reaction primarily stains carbohydrates, we could exploit the circumstance that different collagen types vary in carbohydrate content. Contrary to fasciae, tissues such as muscle, bone, nerves and blood vessels exhibit significantly less staining or remain unstained. Read More

    An Augmented Reality magic mirror as additive teaching device for gross anatomy.
    Ann Anat 2018 Jan 7;215:71-77. Epub 2017 Oct 7.
    Ludwig-Maximilians-Universiät, Chair of Vegetative Anatomy, Faculty of Medicine, Munich, Germany. Electronic address:
    When preparing young medical students for clinical activity, it is indispensable to acquaint them with anatomical section images which enable them to use the clinical application of imaging methods. A new Augmented Reality Magic Mirror (AR MM) system, which provides the advantage of a novel, interactive learning tool in addition to a regular dissection course, was therefore tested and evaluated by 880 first-year medical students as part of the macroscopic anatomy course in 2015/16 at Ludwig-Maximilians-Universität (LMU) in Munich. The system consists of an RGB-D sensor as a real-time tracking device, which enables the system to link a deposited section image to the projection of the user's body, as well as a large display mimicking a real-world physical mirror. Read More

    Introducing a simple method of maxillary sinus volume assessment based on linear dimensions.
    Ann Anat 2018 Jan 28;215:47-51. Epub 2017 Sep 28.
    Department of Oral Rehabilitation, Division of Prosthodontics, Poznań University of Medical Sciences, Poznań, Poland.
    Measuring sinus volume in a general practice clinic is a complex and time-consuming procedure, requiring experience in the use of radiological methods In the presented research, the automatically estimated maxillary sinus volume was compared with maxillary sinus volume assessed with mathematical formulas used to calculate the volume of spheres and pyramids. The starting point for the statistical analysis were specific measurements of the sinuses. We wanted to discover which geometric shape has the volume that is nearest to the automatically estimated volume. Read More

    Bodies of children in the Institute of Anatomy in Halle (Saale), Germany, between 1920 and 1945.
    Ann Anat 2018 Jan 27;215:40-46. Epub 2017 Sep 27.
    Department of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, Faculty of Medicine, Große Steinstraße 52, D-06097 Halle (Saale), Germany. Electronic address:
    At the Institute of Anatomy and Cell Biology in Halle (Saale) 74 children's bodies of unknown historical provenance are being held in storage. The aim of this study was the evaluation of their identities, the circumstances of their acquisition, as well as the documentation of their individual characteristics. For these purposes, all bodies were comprehensively examined and photo-documented. Read More

    Calcium-binding proteins expression in the septum and cingulate cortex of the adult guinea pig.
    Ann Anat 2018 Jan 24;215:30-39. Epub 2017 Sep 24.
    Department of Comparative Anatomy, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Pl. Łódzki 3, 10-727 Olsztyn, Poland. Electronic address:
    For the first time this study demonstrates the distribution pattern and expression of three neuroanatomical markers: calbindin D28k (CB), calretinin (CR) and parvalbumin (PV) in topographically connected brain regions - the septum (SE) and the cingulate cortex (CC). The co-existence among calcium-binding proteins (CaBPs) was also examined. The study was conducted on the adult guinea pig with the use of immunohistochemical and molecular biological techniques. Read More

    Gonial angle growth patterns according to age and gender.
    Ann Anat 2018 Jan 24;215:93-96. Epub 2017 Sep 24.
    Department of Anatomy and Human Embryology, University of Valencia, Faculty of Medicine, Avda. Blasco Ibanez 15, E46010 Valencia, Spain. Electronic address:
    Currently there are controversial results about gender and age differences in human gonial angle values. In this context we aimed to ascertain the gender and age differences in the gonial angle values of young Caucasian Mediterranean subjects. We tested the hypothesis of a relation between the gonial angle values and the gender and age of the subjects by means of a prospective study involving 266 subjects. Read More

    A micro-computed tomographic (micro-CT) analysis of the root canal morphology of maxillary third molar teeth.
    Ann Anat 2018 Jan 24;215:83-92. Epub 2017 Sep 24.
    Division of Restorative Dentistry, Dublin Dental University Hospital, Trinity College Dublin, Lincoln Place, Dublin 2, Ireland.
    Introduction: The aim of this study was to analyze the root canal morphology of maxillary third molars (MTMs) using micro-computed tomography (micro-CT).

    Materials And Methods: Seventy-eight consecutively-extracted human MTMs were scanned using micro-CT (spatial resolution=13.68μm per pixel). Read More

    Molecular basis of dental sensitivity: The odontoblasts are multisensory cells and express multifunctional ion channels.
    Ann Anat 2018 Jan 24;215:20-29. Epub 2017 Sep 24.
    Departamento de Morfología y Biología Celular Universidad de Oviedo, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco, Chile. Electronic address:
    Odontoblasts are the dental pulp cells responsible for the formation of dentin. In addition, accumulating data strongly suggest that they can also function as sensory cells that mediate the early steps of mechanical, thermic, and chemical dental sensitivity. This assumption is based on the expression of different families of ion channels involved in various modalities of sensitivity and the release of putative neurotransmitters in response to odontoblast stimulation which are able to act on pulp sensory nerve fibers. Read More

    Effects of ß-TCP scaffolds on neurogenic and osteogenic differentiation of human embryonic stem cells.
    Ann Anat 2018 Jan 24;215:52-62. Epub 2017 Sep 24.
    Science Division, Delta College, University Center, MI 48710, USA.
    Extracellular matrix (ECM) and adhesion molecules play crucial roles in regulating growth and differentiation of stem cells. The current study aimed to investigate the effects of beta-tricalcium phosphate (ß-TCP) scaffolds on differentiation and expression of ECM and adhesion molecules of human embryonic stem cells (hESCs). Undifferentiated hESCs were seeded on ß-TCP scaffolds and cell culture plates and cultured in growth and osteogenic medium for 21 days. Read More

    Phospholipase C zeta parameters in sperm from polymorphic teratozoospermic men.
    Ann Anat 2018 Jan 24;215:63-70. Epub 2017 Sep 24.
    Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Teratozoospermia is a disorder associated with high abnormal sperm morphology which affects fertility in males. In recent years, it has been described that biomarker-based sperm quality evaluation can alleviate male infertility treatment. Phospholipase C zeta (PLCζ) is a sperm-specific factor which appears to be a predicting biomarker for fertilization potential of males. Read More

    Comparative postnatal histomorphogenesis of the mandible in wild and laboratory mice.
    Ann Anat 2018 Jan 18;215:8-19. Epub 2017 Sep 18.
    Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia, Facultat de Biociències, Universitat Autònoma de Barcelona, Campus de Bellaterra, E-08193 Cerdanyola del Vallès, Spain. Electronic address:
    The coordinated activity of bone cells (i.e., osteoblasts and osteoclasts) during ontogeny underlies observed changes in bone growth rates (recorded in bone histology and bone microstructure) and bone remodeling patterns explaining the ontogenetic variation in bone size and shape. Read More

    Platelet-released growth factors inhibit proliferation of primary keratinocytes in vitro.
    Ann Anat 2018 Jan 18;215:1-7. Epub 2017 Sep 18.
    Department of Dermatology, University Hospital of Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Straße 7, 24105 Kiel, Germany.
    Autologous thrombocyte concentrate lysates as platelet-released growth factors (PRGF) or Vivostat Platelet Rich Fibrin (PRF) represent important tools in modern wound therapy, especially in the treatment of chronic, hard-to-heal or infected wounds. Nevertheless, underlying cellular and molecular mechanisms of the beneficial clinical effects of a local wound therapy with autologous thrombocyte concentrate lysates are poorly understood. Recently, we have demonstrated that PRGF induces antimicrobial peptides in primary keratinocytes and accelerates keratinocytes' differentiation. Read More

    Maxillary sinuses and midface in patients with cleidocranial dysostosis.
    Ann Anat 2018 Jan 6;215:78-82. Epub 2017 Sep 6.
    Department of Oral Rehabilitation, Division of Prosthodontics, Poznań University of Medical Sciences, Poznan, Poland.
    The cleidocranial dysplasia is general skeletal disorder with an autosomal dominant inheritance. It is manifested by many craniofacial abnormalities, of which the maxillary hypoplasia is the most evident. The aim of the study was to use CBCT to evaluate the volume of the maxillary sinuses and the dimensions of maxillae in patients with CCD and compare them with healthy individuals. Read More

    Anatomical connections between the buccinator and the tendons of the temporalis.
    Ann Anat 2017 Nov 1;214:63-66. Epub 2017 Sep 1.
    Department of Anatomy, Institute for Translational & Clinical Research, Catholic Kwandong University College of Medicine, Gangneung, Republic of Korea. Electronic address:
    The aim of this study was to clarify the anatomical relationship between the buccinator and the temporalis in order to improve understanding of the precise and coordinated movements of the mouth and the mandible. The buccinator and the temporalis were investigated in 72 hemifaces from Korean cadavers. Removing the buccal fat pad from the buccinator revealed that the fascia encircled the space between the superficial and deep tendons of the temporalis laterally, and the external surface of the buccinator medially in all specimens (100%). Read More

    In vivo characterization of the murine venous system before and during dobutamine stimulation: implications for preclinical models of venous disease.
    Ann Anat 2017 Nov 1;214:43-52. Epub 2017 Sep 1.
    Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
    Although widely used as a preclinical model for studying venous diseases, there is a scarcity of in vivo characterizations of the naïve murine venous system. Additionally, previous studies on naïve veins (ex vivo) have not included the influence of surrounding structures and biomechanical forces. Using MRI, we noninvasively quantified the cross-sectional area, cyclic strain, and circularity of the venous system in young and old, male and female C57BL/6 mice. Read More

    Expression of myosin heavy chain isoforms mRNA transcripts in the temporalis muscle of common chimpanzees (Pan troglodytes).
    Ann Anat 2017 Nov 1;214:80-85. Epub 2017 Sep 1.
    Unit of Human Anatomy and Embryology, University of Barcelona, C/Casanova 143, 08036 Barcelona, Spain. Electronic address:
    Purpose: The common chimpanzee (Pan troglodytes) is the primate that is phylogenetically most closely related to humans (Homo sapiens). In order to shed light on the anatomy and function of the temporalis muscle in the chimpanzee, we have analyzed the expression patterns of the mRNA transcripts of the myosin heavy chain (MyHC) isoforms in different parts of the muscle.

    Basic Procedures: We dissected the superficial, deep and sphenomandibularis portions of the temporalis muscle in five adult P. Read More

    Can skull form predict the shape of the temporomandibular joint? A study using geometric morphometrics on the skulls of wolves and domestic dogs.
    Ann Anat 2017 Nov 1;214:53-62. Epub 2017 Sep 1.
    Institut für Spezielle Zoologie und Evolutionsbiologie mit Phyletischem Museum, Friedrich-Schiller-Universität, Erbertstrasse 1, 07743 Jena, Germany; Max Planck Weizmann Center for Integrative Archaeology and Anthropology, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.
    The temporomandibular joint (TMJ) conducts and restrains masticatory movements between the mammalian cranium and the mandible. Through this functional integration, TMJ morphology in wild mammals is strongly correlated with diet, resulting in a wide range of TMJ variations. However, in artificially selected and closely related domestic dogs, dietary specialisations between breeds can be ruled out as a diversifying factor although they display an enormous variation in TMJ morphology. Read More

    Immunohistochemical and western blot analysis suggest that the soluble forms of FGF1-2 and FGFR1-2 sustain tail regeneration in the lizard.
    Ann Anat 2017 Nov 18;214:67-74. Epub 2017 Aug 18.
    Comparative Histolab and Department of Biology of the University of Bologna, via Selmi 3, 40126 Bologna, Italy. Electronic address:
    Fibroblast Growth Factors 1-2 (FGF1-2) stimulate tail regeneration in lizards and therefore the distribution of their receptors, FGFR1-2, in the regenerating tail of the lizard. Podarcis muralis has been studied using immunofluorescence and western blotting. Immunoreactive protein bands at 15-16kDa for FGF1-2 in addition to those at 50-65kDa are detected in the regenerating epidermis, but weak bands at 35, 45 and 50kDa appear from the regenerating connective tissues. Read More

    Modulation of macrophage phagocytosis in vitro-A role for cholinergic stimulation?
    Ann Anat 2017 Nov 16;214:31-35. Epub 2017 Aug 16.
    Institute of Anatomy and Cell Biology, Medical Faculty, Saarland University, 66421 Homburg/Saar, Germany. Electronic address:
    Acetylcholine is synthetized and released from neural cells, but also by non-neuronal cells such as epithelial cells or keratinocytes. Cholinergic agonists enhance the phagocytosis of zymosan particles in primary peritoneal macrophages. The aim of this study was to investigate the effect of carbachol stimulation on phagocytosis in a macrophage cell line using microspheres. Read More

    Combined anatomical variations: The mylohyoid bridge, retromolar canal and accessory palatine canals branched from the canalis sinuosus.
    Ann Anat 2017 Nov 16;214:75-79. Epub 2017 Aug 16.
    Division of Removable Prosthodontics, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
    The study of anatomical variations is important not only for collecting anthropometric data, but also for improving clinical protocols and understanding why a particular clinical procedure sometimes does not yield the expected results. We report the case of a 74 year-old patient, in which we observed combined anatomical variants of the mandible and maxillary bone. One of these was the unilateral mylohyoid bridge (MB) of the uncommon, lingular type. Read More

    Age-related remodeling of the JAK/STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level.
    Ann Anat 2017 Nov 4;214:21-30. Epub 2017 Aug 4.
    Department of Anatomy and Embryology, Faculty of Medicine, Cairo University, Egypt. Electronic address:
    Background: The cellular and molecular mechanisms implicated in age-associated changes in myocardial structure are of paramount importance since they cause profound alterations in the functional response and represent targets for alleviating age-related pathologies. One of these mechanisms is the JAK/STAT/SOCS signaling pathway.

    Aim Of The Study: The present study is designed to elucidate age-dependent changes of the myocardium to provide morphological basis displaying the pathogenesis of myocardial hypertrophy, fibrosis and inflammation with aging. Read More

    The protective effect of platelet released growth factors and bone augmentation (Bio-Oss) on ethanol impaired osteoblasts.
    Ann Anat 2017 Nov 31;214:36-42. Epub 2017 Jul 31.
    Institute of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany. Electronic address:
    Background: Chronic alcohol consumption is a known limiting factor for bone healing. One promising strategy to improve bone augmentation techniques with Bio-Ossin oral and maxillofacial surgery might be the supportive application of platelet-concentrated biomaterials as platelet-released growth factor (PRGF). To address this matter, we performed an in vitro study investigating the protective effects of PRGF and Bio-Ossin ethanol (EtOH) treated osteoblasts. Read More

    Radiological evaluation of maxillary sinus anatomy: A cross-sectional study of 300 patients.
    Ann Anat 2017 Nov 29;214:1-8. Epub 2017 Jul 29.
    International Master in Oral Surgery (IMOS), Department of Oral and Maxillofacial Surgery, International University of Catalonia (UIC), Barcelona, Spain.
    Objective: The aim of the present study was to evaluate the principal anatomical characteristics of the maxillary sinus using Cone Beam Computed Tomography (CBCT) in order to facilitate prevention of intra- and post-operative complications.

    Materials And Methods: Three hundred CBCT scans from patients undergoing implant surgery were analysed. The following anatomical structures were evaluated: (1) Residual ridge height (RRH) and width (RRW); (2) Ridge bone density (BD); (3) Maxillary sinus angle (MSA); (4) Maxillary sinus lateral wall thickness (LWT); (5) Schneiderian membrane thickness (MT); (6) Maxillary sinus septa (SS); (7) Posterior superior alveolar artery (PSAA). Read More

    Online Embryology teaching using learning management systems appears to be a successful additional learning tool among Egyptian medical students.
    Ann Anat 2017 Nov 29;214:9-14. Epub 2017 Jul 29.
    Anatomy and Embryology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address:
    Although the traditional didactic lecture is considered to be efficient for presenting information and providing explanations, it usually does not provide adequate time for deeper learning activities. So, traditional lecture is one of the most widely criticized educational methods. Virtual learning environment (VLE) is a specially designed environment that facilitates teachers' management of educational courses for their students, using computer hardware and software, which involves distance learning. Read More

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