Search Our Scientific Publications & Authors

Liver Cancer 2021 Apr 2;10(2):137-150. Epub 2021 Feb 2.

Department of Liver Surgery, Peking Union Medical College (PUMC) Hospital, PUMC and Chinese Academy of Medical Sciences, Beijing, China.

Introduction: Over the past 4 decades, the management of hepatocellular carcinoma (HCC) has changed dramatically. The publications that have had the most significant impact on HCC management have not been quantitatively analyzed. In this article, we analyzed the 100 most influential articles over the past 4 decades using bibliometric citation analysis to characterize the evolution in HCC treatment. Read More

Ann Plast Surg 2021 May;86(5S Suppl 3):S353

From the Division of Plastic Surgery, Stanford University, Palo Alto, CA.

Ann Intern Med 2021 May 11. Epub 2021 May 11.

University of Minnesota, Minneapolis, Minnesota (D.Z.).

HSS J 2021 Feb 21;17(1):14-17. Epub 2021 Feb 21.

Hospital for Special Surgery, New York, NY, USA.

Ann N Y Acad Sci 2021 May 4. Epub 2021 May 4.

The Nour Foundation, New York, New York.

The broad implications of acknowledging and embracing the emotions of awe and wonder are discussed in this special issue of Annals of the New York Academy of Sciences, from their role as an incentive or impediment to scientific progress, to the many ways in which they connect to aesthetic experience, religious attitudes, and ethical concerns. Read More

Ann Intern Med 2021 May 4:OC1. Epub 2021 May 4.

University of Alabama at Birmingham, Birmingham, Alabama (T.M.S.).

Ann Intern Med 2021 May 4. Epub 2021 May 4.

Duke University, Durham, North Carolina (S.M.).

Ann Emerg Med 2021 Apr 28. Epub 2021 Apr 28.

Department of Emergency Medicine, University of California, Los Angeles, Los Angeles, CA.

We performed a methodological appraisal of the history, electrocardiogram, age, risk factors, and troponin (HEART) score and its variants in the context of Annals of Emergency Medicine's methodological standards for clinical decision rules. We note that this chest pain risk stratification tool was not formally derived, omits sex and other known predictors, has weak interrater reliability, and its 0, 1, and 2 score weightings do not align with their known predictivities. Its summary performance (pooled sensitivities of 96% to 97% with lower confidence interval bounds of 93% to 94%) is below that which emergency physicians state a willingness to accept, below the 98% sensitivity exhibited by baseline practice without the score, and below the 1% to 2% acceptable miss threshold specified by the American College of Emergency Physicians chest pain policy. Read More

J Clin Epidemiol 2021 Apr 26. Epub 2021 Apr 26.

Univ Rennes, CHU Rennes, Inserm, CIC 1414 [(Centre d'Investigation Clinique de Rennes)], F-35000 Rennes, France.

Objective: To explore the impact of the Annals of Internal Medicine (AIM) data-sharing policy for randomized controlled trials (RCTs) in terms of output from data-sharing (i.e. publications re-using the data). Read More

Ann Dermatol 2020 Oct 29;32(5):353-359. Epub 2020 Sep 29.

Department of Parasitology and Institute of Medical Education, College of Medicine, Hallym University, Chuncheon, Korea.

has not been deposited in PubMed Central (PMC) since October 2018 due to inadequate scientific quality, including the absence of informed consent in three case reports with patients' photos. This study examined the readiness of to be deposited in PMC again by analyzing the 13 issues published from October 2018 to August 2020. The journal's scientific quality and ethical standards were assessed, and adherence to these standards was documented. Read More

Ann Emerg Med 2021 05;77(5):550-551

Vanderbilt University Medical Center, Nashville, TN.

Ann Intern Med 2021 Apr 27. Epub 2021 Apr 27.

University of Texas, Austin, Texas (G.E.F.).

Ann Oncol 2021 Jun 20;32(6):821. Epub 2021 Apr 20.

Comprehensive Cancer Center, Institute of Experimental Cancer Research, University Hospital Ulm, Ulm, Germany.

Ann Intern Med 2021 Apr;174(4):HO2-HO3

University of British Columbia, BC Cancer, and Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada (A.Y.Y.L.).

Ann Intern Med 2021 Apr;174(4):HO4

From Michigan Medicine and VA Ann Arbor Healthcare System, Ann Arbor, Michigan (D.H.W, J.A., M.L.).

Ann Intern Med 2021 Apr;174(4):OC2

University of Ottawa and Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada (V.T.).

Ann Intern Med 2021 04;174(4):CG1

Thomas Jefferson University, Philadelphia, Pennsylvania (G.J.M., H.H.W.).

Ann Intern Med 2021 Apr;174(4):ED4

J Craniofac Surg 2021 Apr 15. Epub 2021 Apr 15.

Houston, TX.

Data Brief 2021 Apr 16;35:106953. Epub 2021 Mar 16.

Vascular and Endovascular Surgery Division, Department of Surgery, Laboratory for Medical Investigation #2, (LIM 02), University of São Paulo School of Medicine (FMUSP), Av. Dr. Arnaldo, 455 - Cerqueira César - Postal code: 01246903 - Room 1312, São Paulo, SP, Brazil.

This data article describes biomechanical and histological information of abdominal aortas harvested in autopsy. Eight abdominal aorta aneurysms (AAA) and 30 normal diameter abdominal aortas were collected and submitted to an inflation test up to their rupture. This inflation procedure was part of the research entitled "Experimental study of rupture pressure and elasticity of abdominal aortic aneurysms found at autopsy", submitted to Annals of Vascular Surgery. Read More

Ann Transl Med 2021 Mar;9(6):515

Division of Cardiovascular Diseases, Texas Tech University Health Science Center El Paso, El Paso, Texas, USA.

Ann Transl Med 2021 Mar;9(6):510

Department of Woman, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

The ovarian cancer recurrence occurs in 75% of patients with advanced FIGO stage, and its treatment is a challenge for the oncologist in gynecology. The standard treatment of recurrent ovarian cancer (ROC) usually includes intravenous chemotherapy according to platinum sensitivity. Furthermore, maintenance treatment with target therapies [e. Read More

Ann Transl Med 2021 Mar;9(6):477

Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: This study aimed to investigate the microbiol distribution of intra-abdominal infection in patients with acute pancreatitis, and to develop a reliable prediction model to guide the use of antibiotics.

Methods: Inpatient with acute pancreatitis between January 2015 and June 2020 were enrolled in the study. Participants were divided into the intra-abdominal infection group and non-infection group. Read More

Lancet 2021 Apr 9. Epub 2021 Apr 9.

Institute of Neurogenetics and Department of Neurology, University of Lübeck and University Hospital Schleswig-Holstein, Lübeck, Germany.

Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; the rising prevalence worldwide resembles the many characteristics typically observed during a pandemic, except for an infectious cause. In most populations, 3-5% of Parkinson's disease is explained by genetic causes linked to known Parkinson's disease genes, thus representing monogenic Parkinson's disease, whereas 90 genetic risk variants collectively explain 16-36% of the heritable risk of non-monogenic Parkinson's disease. Read More

Ann Intern Med 2021 Apr 13;174(4):W37-W44. Epub 2021 Apr 13.

Medical College of Wisconsin, Milwaukee, Wisconsin (A.K., T.M.).

Ann Transl Med 2021 Mar;9(5):424

Department of Thoracic Surgery/Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory and National Clinical Research Center for Respiratory Disease, Guangzhou, China.

Immunotherapy has been proved to be a promising candidate for advanced non-small cell lung cancer (NSCLC). Despite MET mutations are regarded as an independent factor of programmed death ligand 1 (PD-L1) high expression, the efficacy of immune checkpoint inhibitors (ICIs) across NSCLC harboring Mesenchymal-epithelial transition factor exon 14 skipping alteration (METex14) is still uncleared. Moreover, when the resistance of PD-1 antibody occurs, the questions of how to interpret the resistance and how to overcome the resistance are worth exploring. Read More

Ann Transl Med 2021 Mar;9(5):423

Medical School, University of Ioannina, Ioannina, Greece.

Vaccines, cytokines, and adoptive cellular therapies (ACT) represent immuno-therapeutic modalities with great development potential, and they are currently approved for the treatment of a limited number of advanced malignancies. The most up-to-date knowledge on the regulation of the anti-cancer immune response has recently led to the development and approval of inhibitors of immune checkpoints, which have produced unprecedented clinical activity in several hard to treat solid malignancies. However, severe adverse events (AEs) represent a limitation to the use of these drugs. Read More

Ann Transl Med 2021 Mar;9(5):407

Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, China.

Background: Primary pulmonary mucoepidermoid carcinoma (PMEC) is a rare malignant tumor, and the clinical manifestations lack specificity. The study evaluates the prognostic factors and constructs a practicable nomogram to estimate the individualized survival status for PMEC patients.

Methods: Surveillance, Epidemiology, and End Results (SEER) database was used to selected eligible patients between 1975 and 2016. Read More

Ann Transl Med 2021 Mar;9(5):404

School of Medicine, Southeast University, Nanjing, China.

Background: Umbilical cord mesenchymal stem cells (UC-MSCs), which possess potent immunomodulatory effects and low immunogenicity, are considered to be a promising stem cell-based therapy for sepsis. In the current study, we aimed to investigate whether the combined use of UC-MSCs and imipenem has a better effect than imipenem alone in treating ()-induced sepsis and to explore the mechanism by which UC-MSCs exert their therapeutic effect in septic mice.

Methods: We randomly divided mice into five groups with 10 mice in each group: the normal control group (control group), the sepsis group (vehicle group), the MSCs treatment group (MSCs group), the imipenem treatment group (imipenem group), and the imipenem plus MSCs treatment group (imipenem + MSCs group). Read More

Ann Transl Med 2021 Mar;9(5):403

Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, China.

Background: Subxiphoid approach for mediastinal tumor resection was reported to provide a better view and less postoperative pain. Non-intubated video-assisted thoracic surgery (NI-VATS) without muscle relaxant would decrease the possibility of postoperative airway collapse for anterior mediastinal mass operation. Herein, we sought to describe the use of NI-VATS through subxiphoid approach for anterior mediastinal tumor resection. Read More