682 results match your criteria Annals Of Intensive Care[Journal]


A clinical evaluation of two central venous catheter stabilization systems.

Ann Intensive Care 2019 Apr 17;9(1):49. Epub 2019 Apr 17.

Corporate Division, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham, B15 2WB, UK.

Background: Central venous catheters (CVCs) are commonly secured with sutures which are associated with microbial colonization and infection. We report a comparison of a suture-free system with standard sutures for securing short-term CVC in an international multicentre, prospective, randomized, non-blinded, observational feasibility study. Consented critical care patients who had a CVC inserted as part of their clinical management were randomized to receive either sutures or the suture-free system to secure their CVC. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
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http://dx.doi.org/10.1186/s13613-019-0519-6DOI Listing
April 2019
1 Read

Update in Neurocritical Care: a summary of the 2018 Paris international conference of the French Society of Intensive Care.

Ann Intensive Care 2019 Apr 16;9(1):47. Epub 2019 Apr 16.

Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles (ULB), Route de Lennik, 808, 1070, Brussels, Belgium.

The 2018 Paris Intensive Care symposium entitled "Update in Neurocritical Care" was organized in Paris, June 21-22, 2018, under the auspices of the French Intensive Care Society. This 2-day post-graduate educational symposium comprised several chapters, aiming first to provide all-board intensivists with current standards for the clinical assessment of altered consciousness states (including coma and delirium) and peripheral nervous system in critically ill patients, monitoring of brain function (specifically, electro-encephalography) and best practices for sedation-analgesia-delirium management. An update on the treatment of specific severe brain pathologies-including ischaemic/haemorrhagic stroke, cerebral venous thrombosis, hypoxic-ischaemic brain injury, immune-mediated and infectious encephalitis and refractory status epilepticus-was also provided. Read More

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http://dx.doi.org/10.1186/s13613-019-0523-xDOI Listing
April 2019
1 Read

Determinants of left ventricular ejection fraction and a novel method to improve its assessment of myocardial contractility.

Ann Intensive Care 2019 Apr 16;9(1):48. Epub 2019 Apr 16.

Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, USA.

Background: The aim of this study was to quantify the impact of different cardiovascular factors on left ventricular ejection fraction (LVEF) and test a novel LVEF calculation considering these factors.

Results: 10 pigs were studied. The experimental protocol consisted of sequentially changing afterload, preload and contractility. Read More

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http://dx.doi.org/10.1186/s13613-019-0526-7DOI Listing

Predictive analytics: beyond the buzz.

Ann Intensive Care 2019 Apr 11;9(1):46. Epub 2019 Apr 11.

Bicetre University Hospital, Paris South University, Le Kremlin Bicetre, France.

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http://dx.doi.org/10.1186/s13613-019-0524-9DOI Listing

Risk factors for progression toward brain death after out-of-hospital cardiac arrest.

Ann Intensive Care 2019 Apr 8;9(1):45. Epub 2019 Apr 8.

Hospices Civils de Lyon, Hôpital Edouard Herriot, Service de Médecine Intensive-Réanimation, 5, Place d'Arsonval, 69437, Lyon Cedex 03, France.

Background: Successfully resuscitated out-of-hospital cardiac arrest (OHCA) may lead to brain death (BD) and good-quality transplantable organs. We aimed to determine risk factors for evolution toward BD after OHCA. We analyzed adult patients admitted to an intensive care unit (ICU) who survived at least 24 h after an OHCA between 2005 and 2015. Read More

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http://dx.doi.org/10.1186/s13613-019-0520-0DOI Listing
April 2019
2 Reads

Airway pressure release ventilation during acute hypoxemic respiratory failure: a systematic review and meta-analysis of randomized controlled trials.

Ann Intensive Care 2019 Apr 4;9(1):44. Epub 2019 Apr 4.

Anesthesia and Intensive Care Unit, Università Politecnica delle Marche, Ancona, Italy.

Background: Airway pressure release ventilation (APRV) has been considered a tempting mode of ventilation during acute respiratory failure within the concept of open lung ventilation. We performed a systematic review and meta-analysis to verify whether adult patients with hypoxemic respiratory failure have a higher number of ventilator-free days at day 28 when ventilated in APRV compared to conventional ventilation strategy. Secondary outcomes were difference in PaO/FiO at day 3, ICU length of stay (LOS), ICU and hospital mortality, mean arterial pressure (MAP), risk of barotrauma and level of sedation. Read More

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http://dx.doi.org/10.1186/s13613-019-0518-7DOI Listing
April 2019
5 Reads

Gender and survival of critically ill patients: results from the FROG-ICU study.

Ann Intensive Care 2019 Mar 29;9(1):43. Epub 2019 Mar 29.

Department of Cardiology, University Hospital Zurich, Zurich, Switzerland.

Purpose: Few studies analyzed gender-related outcome differences of critically ill patients and found inconsistent results. This study aimed to test the independent association of gender and long-term survival of ICU patients.

Materials And Methods: FROG-ICU was a prospective, observational, multi-center cohort designed to investigate the long-term mortality of critically ill adult patients. Read More

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http://dx.doi.org/10.1186/s13613-019-0514-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441070PMC
March 2019
1 Read

Chest CT scan and alveolar procollagen III to predict lung fibroproliferation in acute respiratory distress syndrome.

Ann Intensive Care 2019 Mar 27;9(1):42. Epub 2019 Mar 27.

Médecine Intensive Réanimation Détresses Respiratoires et Infection Sévères, AP-HM, CHU Nord, chemin des Bourrely, 13015, Marseille, France.

Background: Lung fibroproliferation in ARDS patients is associated with mortality. Alveolar procollagen III (NT-PCP-III) is a validated biomarker of lung fibroproliferation. A chest CT scan could be useful for the diagnosis of lung fibroproliferation. Read More

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http://dx.doi.org/10.1186/s13613-019-0516-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437222PMC
March 2019
1 Read

Does volatile sedation with sevoflurane allow spontaneous breathing during prolonged prone positioning in intubated ARDS patients? A retrospective observational feasibility trial.

Ann Intensive Care 2019 Mar 25;9(1):41. Epub 2019 Mar 25.

Department of Anesthesiology and Critical Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

Background: Lung-protective ventilation and prolonged prone positioning (PP) are presented as essential in treating acute respiratory distress syndrome (ARDS). The optimal respirator mode, however, remains controversial. Pressure-supported spontaneous breathing (PS) during ARDS provides several advantages, but is difficult to achieve during PP because of respiratory depression as a side effect of sedative drugs. Read More

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http://dx.doi.org/10.1186/s13613-019-0517-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434001PMC
March 2019
1 Read

Pulmonary infections prime the development of subsequent ICU-acquired pneumonia in septic shock.

Ann Intensive Care 2019 Mar 15;9(1):39. Epub 2019 Mar 15.

Service de médecine intensive-réanimation, Hôpital Cochin, Hôpitaux Universitaires Paris-Centre, Assistance Publique - Hôpitaux de Paris, 27 Rue du Faubourg Saint-Jacques, 75014, Paris, France.

Purpose: To investigate the determinants and the prognosis of intensive care unit (ICU)-acquired pneumonia in patients with septic shock.

Methods: This single-center retrospective study was conducted in a medical ICU in a tertiary care center from January 2008 to December 2016. All consecutive patients diagnosed for septic shock within the first 48 h of ICU admission were included. Read More

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http://dx.doi.org/10.1186/s13613-019-0515-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420540PMC
March 2019
1 Read

Correction to: Risk factors for mortality in elderly and very elderly critically ill patients with sepsis: a prospective, observational, multicenter cohort study.

Ann Intensive Care 2019 Mar 13;9(1):36. Epub 2019 Mar 13.

Critical care Center, Corporacion Sanitaria Universitaria Parc Tauli, CIBER Enfermedades Respiratorias, Autonomous University of Barcelona, Sabadell, Spain.

Following the publication of the original article [1], the author reported a mistake in Fig. 1. Read More

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http://dx.doi.org/10.1186/s13613-019-0508-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419791PMC

Associations between tricuspid annular plane systolic excursion to reflect right ventricular function and acute kidney injury in critically ill patients: a SICS-I sub-study.

Ann Intensive Care 2019 Mar 13;9(1):38. Epub 2019 Mar 13.

Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Background: Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurrence of AKI in critically ill patients.

Methods: In this prospective cohort study, we included all patients acutely admitted to an intensive care unit (ICU). Read More

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http://dx.doi.org/10.1186/s13613-019-0513-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419793PMC

Narrative review: clinical assessment of peripheral tissue perfusion in septic shock.

Ann Intensive Care 2019 Mar 13;9(1):37. Epub 2019 Mar 13.

Service de réanimation médicale, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France.

Sepsis is one of the main reasons for intensive care unit admission and is responsible for high morbidity and mortality. The usual hemodynamic targets for resuscitation of patients with septic shock use macro-hemodynamic parameters (hearth rate, mean arterial pressure, central venous pressure). However, persistent alterations of microcirculatory blood flow despite restoration of macro-hemodynamic parameters can lead to organ failure. Read More

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http://dx.doi.org/10.1186/s13613-019-0511-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419794PMC
March 2019
3 Reads

Response to the letter to the Editor "Comparing video and direct laryngoscopy for tracheal intubation in the general ward" by Shao and Colleagues.

Ann Intensive Care 2019 Mar 7;9(1):34. Epub 2019 Mar 7.

Department of Pulmonary and Critical Care Medicine, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.

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http://dx.doi.org/10.1186/s13613-019-0510-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405780PMC

Correction to: Effects of the timing of administration of IgM- and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of septic shock patients.

Ann Intensive Care 2019 Mar 5;9(1):33. Epub 2019 Mar 5.

Department of Anesthesia, Resuscitation and Pain Therapy, Cattinara Hospital, University of Trieste, Strada di Fiume 447, 34149, Trieste, Italy.

Following publication of the original article [1], we have been notified that the tagging of the author name was done incorrectly in the XML version of the paper. The correct given name is Michele Claudio, and the family name is Vassallo. Read More

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http://dx.doi.org/10.1186/s13613-019-0504-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401037PMC
March 2019
1 Read

Management of hyperkalemia in the acutely ill patient.

Ann Intensive Care 2019 Feb 28;9(1):32. Epub 2019 Feb 28.

GH St-Louis-Lariboisière, Department of Anesthesiology and Critical Care and Burn Unit, St-Louis Hospital, Assistance Publique-Hopitaux de Paris, Paris, France.

Purpose: To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients.

Methods: We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1, 2018, in accordance with the PRISMA Statement using the following terms: "hyperkalemia," "intensive care," "acute kidney injury," "acute kidney failure," "hyperkalemia treatment," "renal replacement therapy," "dialysis," "sodium bicarbonate," "emergency," "acute." Reports from within the past 10 years were selected preferentially, together with highly relevant older publications. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13613-019-0509-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395464PMC
February 2019
10 Reads

Invasive pulmonary aspergillosis in cirrhotic patients: analysis of a 10-year clinical experience.

Ann Intensive Care 2019 Feb 18;9(1):31. Epub 2019 Feb 18.

Ecole Nationale Vétérinaire d'Alfort (ENVA), Faculté de Médecine de Créteil, EA Dynamyc Université Paris-Est Créteil (UPEC), 8 rue du Général Sarrail, 94010, Créteil, France.

Background: Cirrhosis is not recognised as one of the main risk factors of invasive pulmonary aspergillosis (IPA), although its prevalence is increasing. The aim of our study was to identify factors for IPA in such patients with a positive Aspergillus sp. culture in respiratory samples and to evaluate its impact on outcome. Read More

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http://dx.doi.org/10.1186/s13613-019-0502-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379500PMC
February 2019

Effects of chloride content of intravenous crystalloid solutions in critically ill adult patients: a meta-analysis with trial sequential analysis of randomized trials.

Ann Intensive Care 2019 Feb 13;9(1):30. Epub 2019 Feb 13.

Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.

Background: Intravenous crystalloid solutions are administered commonly for critically ill patients. We performed this meta-analysis of randomized trials with trial sequential analysis (TSA) to evaluate effects of chloride content of intravenous crystalloid solutions on clinical outcomes among critically ill adult patients.

Methods: Electronic databases were searched up to June 1, 2018, for randomized trials of use of balanced crystalloids versus 0. Read More

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http://dx.doi.org/10.1186/s13613-019-0506-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374495PMC
February 2019
3 Reads

The association of intravenous insulin and glucose infusion with intensive care unit and hospital mortality: a retrospective study.

Ann Intensive Care 2019 Feb 11;9(1):29. Epub 2019 Feb 11.

Department of Endocrinology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Background: We assessed the association of intravenous insulin and glucose infusion with intensive care unit (ICU) and hospital mortality.

Methods: For this retrospective association study, we used data from all patients admitted to a medical-surgical ICU between January 2012 and September 2017. We excluded patients admitted < 24 h, patients with a diabetic ketoacidosis, patients with a therapy restriction upon ICU admission and readmissions. Read More

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http://dx.doi.org/10.1186/s13613-019-0507-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370891PMC
February 2019
1 Read

Renal protection in sepsis: Is hypertonic sodium (lactate) the solution?

Ann Intensive Care 2019 Feb 8;9(1):28. Epub 2019 Feb 8.

Ageing and Pathology Research Group, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1186/s13613-019-0505-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368633PMC
February 2019
1 Read

The clinical efficacy of intravenous IgM-enriched immunoglobulin (pentaglobin) in sepsis or septic shock: a meta-analysis with trial sequential analysis.

Ann Intensive Care 2019 Feb 6;9(1):27. Epub 2019 Feb 6.

Department of Pathology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, Guangdong Province, People's Republic of China.

Background: Sepsis is characterized by a complex immune response. This meta-analysis evaluated the clinical effectiveness of intravenous IgM-enriched immunoglobulin (IVIgGM) in patients with sepsis and septic shock.

Methods: Four databases, PubMed, the Cochrane Library, the ISI Web of Knowledge, and Embase, were systematically searched from inception to June 2018 to update the 2013 edition of the Cochrane review by two investigators, who independently selected studies, extracted relevant data, and evaluated study quality. Read More

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http://dx.doi.org/10.1186/s13613-019-0501-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365591PMC
February 2019
4 Reads

Risk factors for mortality in elderly and very elderly critically ill patients with sepsis: a prospective, observational, multicenter cohort study.

Ann Intensive Care 2019 Feb 4;9(1):26. Epub 2019 Feb 4.

Critical care Center, Corporacion Sanitaria Universitaria Parc Tauli, CIBER Enfermedades Respiratorias, Autonomous University of Barcelona, Sabadell, Spain.

Background: Age has been traditionally considered a risk factor for mortality in elderly patients admitted to intensive care units. The aim of this prospective, observational, multicenter cohort study is to determine the risk factors for mortality in elderly and very elderly critically ill patients with sepsis.

Results: A total of 1490 patients with ≥ 65 years of age were included in the study; most of them 1231 (82. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13613-019-0495-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362175PMC
February 2019
16 Reads

Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know?

Ann Intensive Care 2019 Feb 1;9(1):25. Epub 2019 Feb 1.

Medical Intensive Care Unit, APHP, Hôpital Saint-Louis, Paris, France.

Checkpoint protein inhibitor antibodies (CPI), including cytotoxic T-lymphocyte-associated antigen 4 inhibitors (ipilimumab, tremelimumab) and the programmed cell death protein 1 pathway/programmed cell death protein 1 ligand inhibitors (pembrolizumab, nivolumab, durvalumab, atezolizumab), have entered routine practice for the treatment of many cancers. They improve the outcome for many cancers, and more patients will be treated with CPI in the future. Although CPI can lead to adverse events (AE) less frequently than for chemotherapy, their use can require intensive care unit admission in case of severe immune-related adverse events (IrAE). Read More

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http://dx.doi.org/10.1186/s13613-019-0487-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358632PMC
February 2019
2 Reads

Impact of levosimendan on weaning from peripheral venoarterial extracorporeal membrane oxygenation in intensive care unit.

Ann Intensive Care 2019 Feb 1;9(1):24. Epub 2019 Feb 1.

Réanimation polyvalente, Centre Hospitalier Universitaire Félix Guyon, 97405, Saint-Denis, Allée des Topazes, France.

Background: Few data are available on the impact of levosimendan in refractory cardiogenic shock patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). The aim of this study was to evaluate the impact of levosimendan on VA-ECMO weaning in patients hospitalized in intensive care unit (ICU).

Methods: This retrospective cohort study was conducted in a French university hospital from 2010 to 2017. Read More

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http://dx.doi.org/10.1186/s13613-019-0503-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358626PMC
February 2019
1 Read

Hemoadsorption therapy in the critically ill: solid base but clinical haze.

Ann Intensive Care 2019 Jan 31;9(1):22. Epub 2019 Jan 31.

Ageing and Pathology Research Group, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1186/s13613-019-0491-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355888PMC
January 2019

Factors associated with renal Doppler resistive index in critically ill patients: a prospective cohort study.

Ann Intensive Care 2019 Jan 31;9(1):23. Epub 2019 Jan 31.

Emergency Medicine Discipline, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Av Enéas de Carvalho Aguiar 255 Sala 5023, São Paulo, SP, Postal Code: 05403-000, Brazil.

Background: The renal Doppler resistive index (renal RI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. However, many parameters have been described as influential on the values of renal RI. Therefore, we proposed this study to evaluate the variables that could impact renal RI in critically ill patients. Read More

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http://dx.doi.org/10.1186/s13613-019-0500-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355884PMC
January 2019

Current use of vasopressors in septic shock.

Ann Intensive Care 2019 Jan 30;9(1):20. Epub 2019 Jan 30.

Service de Réanimation Médicale, Hôpital de Bicêtre, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, France.

Background: Vasopressors are commonly applied to restore and maintain blood pressure in patients with sepsis. We aimed to evaluate the current practice and therapeutic goals regarding vasopressor use in septic shock as a basis for future studies and to provide some recommendations on their use.

Methods: From November 2016 to April 2017, an anonymous web-based survey on the use of vasoactive drugs was accessible to members of the European Society of Intensive Care Medicine (ESICM). Read More

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http://dx.doi.org/10.1186/s13613-019-0498-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353977PMC
January 2019
8 Reads

The prognostic accuracy evaluation of SAPS 3, SOFA and APACHE II scores for mortality prediction in the surgical ICU: an external validation study and decision-making analysis.

Ann Intensive Care 2019 Jan 30;9(1):18. Epub 2019 Jan 30.

Intensive Care Unit, Discipline of Physiology and Surgical Metabology, Department of Surgery, Faculty of Medical Sciences, State University of Campinas (Unicamp), Tessália Viera de Camargo St. 126, University Town Zeferino Vaz, Campinas, São Paulo, 13083-887, Brazil.

Background: The early postoperative period is critical for surgical patients. SOFA, SAPS 3 and APACHE II are prognostic scores widely used to predict mortality in ICU patients. This study aimed to evaluate these index tests for their prognostic accuracy for intra-ICU and in-hospital mortalities as target conditions in patients admitted to ICU after urgent or elective surgeries and to test whether they aid in decision-making. Read More

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http://dx.doi.org/10.1186/s13613-019-0488-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353976PMC
January 2019

Comparing video and direct laryngoscopy for tracheal intubation in the general ward.

Ann Intensive Care 2019 Jan 30;9(1):21. Epub 2019 Jan 30.

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, NO. 95 Yong-An Road, Xi-Cheng District, Beijing, 100050, People's Republic of China.

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http://dx.doi.org/10.1186/s13613-018-0476-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353973PMC
January 2019

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study.

Ann Intensive Care 2019 Jan 30;9(1):19. Epub 2019 Jan 30.

Department of Anesthesiology, Heidelberg University Hospital, 110, Im Neuenheimer Feld, 69120, Heidelberg, Germany.

Background: Septic coagulopathy represents a very dynamic disease entity, tilting from initial hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt disseminated intravascular coagulation. Acute fibrinolysis shutdown has recently been described to be a crucial component of initial hypercoagulability in critically ill patients, although the underlying pathomechanisms, the specific temporal kinetics and its outcome relevance in patients with sepsis remain to be determined.

Methods: In total, 90 patients (30 with septic shock, 30 surgical controls and 30 healthy volunteers) were enrolled. Read More

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http://dx.doi.org/10.1186/s13613-019-0499-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353981PMC
January 2019
4 Reads

Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation.

Ann Intensive Care 2019 Jan 25;9(1):17. Epub 2019 Jan 25.

Medical and Infectious Diseases Intensive Care Unit, AP-HP, Bichat-Claude Bernard University Hospital, 46 rue Henri Huchard, 75877, Paris Cedex, France.

Background: Infectious complications are a major cause of morbidity and mortality after heart transplantation (HT). However, the epidemiology and outcomes of these infections in the recent population of adult heart transplant recipients have not been investigated.

Methods: We conducted a single-center retrospective study on infectious complications occurring within 180 days following HT on consecutive heart transplant recipients, from January 2011 to June 2015 at Bichat University Hospital in Paris, France. Read More

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http://dx.doi.org/10.1186/s13613-019-0490-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347647PMC
January 2019
3 Reads

Lung ultrasound estimation of pleural effusion fluid and the importance of patient position.

Ann Intensive Care 2018 Dec 17;8(1):125. Epub 2018 Dec 17.

Division of Anesthesia and Intensive Care Medicine, Department of Medicine, University of Udine, P.Le S. Maria della Misericordia 15, 33100, Udine, Italy.

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http://dx.doi.org/10.1186/s13613-018-0471-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344562PMC
December 2018

Concurrent initiation of intra-aortic balloon pumping with extracorporeal membrane oxygenation reduced in-hospital mortality in postcardiotomy cardiogenic shock.

Ann Intensive Care 2019 Jan 23;9(1):16. Epub 2019 Jan 23.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, 167A Beilishi Road, Xi Cheng District, Beijing, 100037, China.

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely used in postcardiotomy cardiac shock (PCS). The factors that affect mortality in patients who receive ECMO for PCS remain unclear. In this study, we analyzed the outcomes, predictive factors and complications of ECMO use for PCS. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13613-019-0496-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344560PMC
January 2019
10 Reads

Lung recruitment: What has computed tomography taught us in the last decade?

Ann Intensive Care 2019 Jan 22;9(1):12. Epub 2019 Jan 22.

SC Anestesia e Rianimazione, Ospedale San Paolo - Polo Universitario, ASST Santi Paolo e Carlo, Via Di Rudinì, Milan, Italy.

Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early phase of ARDS has led to changes in the clinical management in up of thirty percent of the patients. Although CT requires the transportation of the patient to the radiological department and exposes the patient to high dose of radiation, given the several information that CT can offer, it should be applied at least one time, in the early phase in all ARDS patients. Read More

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http://dx.doi.org/10.1186/s13613-019-0497-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342739PMC
January 2019
8 Reads

Experts' guidelines of intubation and extubation of the ICU patient of French Society of Anaesthesia and Intensive Care Medicine (SFAR) and French-speaking Intensive Care Society (SRLF) : In collaboration with the pediatric Association of French-speaking Anaesthetists and Intensivists (ADARPEF), French-speaking Group of Intensive Care and Paediatric emergencies (GFRUP) and Intensive Care physiotherapy society (SKR).

Ann Intensive Care 2019 Jan 22;9(1):13. Epub 2019 Jan 22.

Service USIR-SRPR, hospital de Forcilles, 77150, Férolles-Atilly, France.

Background: Intubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required in emergency situations for patients with an unstable cardiovascular or respiratory system. Under these circumstances, it is a high-risk procedure with life-threatening complications (20-50%). Read More

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http://dx.doi.org/10.1186/s13613-019-0483-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342741PMC
January 2019
13 Reads

Admission to the intensive care unit: the need to study complexity and solutions.

Authors:
Ashraf Roshdy

Ann Intensive Care 2019 Jan 22;9(1):14. Epub 2019 Jan 22.

General Intensive Care Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London, SW17 0QT, UK.

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http://dx.doi.org/10.1186/s13613-019-0494-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342743PMC
January 2019

NUTRI-REAPED study: nutritional assessment of French critically ill children and nutrition practice survey in French-speaking pediatric intensive care units.

Ann Intensive Care 2019 Jan 22;9(1):15. Epub 2019 Jan 22.

Pediatric Intensive Care, Hôpital Femme Mère Enfant, CHU de Nantes, 38 boulevard Jean Monnet, 44093, Nantes, France.

Background: Impaired nutritional status is adversely associated with suboptimal outcomes in critically ill children. Undernutrition at pediatric intensive care unit (PICU) admission ranges from 15 to 65%. A lack of knowledge of the nutritional status of children in French PICUs prevents us from specifically targeting education. Read More

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http://dx.doi.org/10.1186/s13613-019-0493-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342745PMC
January 2019

Correction to: Hypoxemia in the ICU: prevalence, treatment, and outcome.

Authors:

Ann Intensive Care 2019 Jan 21;9(1):10. Epub 2019 Jan 21.

Following publication of the original article [1], we have been notified that only the 11 members of the writing committee are listed as the collaborators of the SRLF Trial group. Read More

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http://dx.doi.org/10.1186/s13613-019-0486-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340909PMC
January 2019

Photoplethysmographic determination of the respiratory rate in acutely ill patients: validation of a new algorithm and implementation into a biomedical device.

Ann Intensive Care 2019 Jan 21;9(1):11. Epub 2019 Jan 21.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, 2725 Ch Ste-Foy, Quebec, QC, G1V 4G5, Canada.

Background: Respiratory rate is among the first vital signs to change in deteriorating patients. The aims of this study were to evaluate the accuracy of respiratory rate measurements using a specifically dedicated reflection-mode photoplethysmographic signal analysis in a pathological condition (PPG-RR) and to validate its implementation within medical devices.

Methods: This study is derived from a data mining project, including all consecutive patients admitted to our ICU (ReaSTOC study, ClinicalTrials. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13613-019-0485-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340913PMC
January 2019
11 Reads

Feasibility of an alternative, physiologic, individualized open-lung approach to high-frequency oscillatory ventilation in children.

Ann Intensive Care 2019 Jan 18;9(1). Epub 2019 Jan 18.

Department of Paediatrics, Division of Paediatric Critical Care Medicine, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Huispost CA 80, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.

Background: High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-lung HFOV strategy based on a corner frequency approach using an initial incremental-decremental mean airway pressure titration manoeuvre, a high frequency (8-15 Hz), and high power to initially target a proximal pressure amplitude (∆P) of 70-90 cm HO, irrespective of age or weight. Read More

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https://annalsofintensivecare.springeropen.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13613-019-0492-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338613PMC
January 2019
12 Reads

Effect of preadmission glucocorticoid therapy on 30-day mortality in critically ill patients: a retrospective study of a mixed ICU population in a tertiary hospital.

Ann Intensive Care 2019 Jan 18;9(1). Epub 2019 Jan 18.

Department of Emergency Medicine, Seoul National University Bundang Hospital, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, Korea.

Background: This study aimed to investigate the association between preadmission glucocorticoid (GC) therapy and 30-day mortality in critically ill patients following admission to an intensive care unit (ICU). We aimed to determine whether this association differed according to daily GC dosage and type. We conducted a retrospective cohort study of adult patients admitted to a single tertiary academic hospital ICU from January 2012 to December 2017. Read More

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http://dx.doi.org/10.1186/s13613-019-0489-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338611PMC
January 2019
6 Reads

Positive end-expiratory pressure titration with electrical impedance tomography and pressure-volume curve in severe acute respiratory distress syndrome.

Ann Intensive Care 2019 Jan 17;9(1). Epub 2019 Jan 17.

Institute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany.

Background: The study objective was to compare titration of positive end-expiratory pressure (PEEP) with electrical impedance tomography (EIT) and with ventilator-embedded pressure-volume loop in severe acute respiratory distress syndrome (ARDS).

Methods: We have designed a prospective study with historical control group. Twenty-four severe ARDS patients (arterial oxygen partial pressure to fractional inspired oxygen ratio, PaO/FiO < 100 mmHg) were included in the EIT group and examined prospectively. Read More

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http://dx.doi.org/10.1186/s13613-019-0484-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336593PMC
January 2019
2 Reads

Weaning failure of cardiovascular origin: how to suspect, detect and treat-a review of the literature.

Ann Intensive Care 2019 Jan 9;9(1). Epub 2019 Jan 9.

First Department of Critical Care, Medical School, National and Kapodistrian University of Athens, "Evangelismos" Hospital, Ipsilantou 45-47, 10676, Athens, Greece.

Among the multiple causes of weaning failure from mechanical ventilation, cardiovascular dysfunction is increasingly recognized as a quite frequent cause that can be treated successfully. In this review, we summarize the contemporary evidence of the most important clinical and diagnostic aspects of weaning failure of cardiovascular origin with special focus on treatment. Pathophysiological mechanisms are complex and mainly include increase in right and left ventricular preload and afterload and potentially induce myocardial ischemia. Read More

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http://dx.doi.org/10.1186/s13613-019-0481-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326918PMC
January 2019
1 Read

Comparison of the accuracy of neutrophil CD64, procalcitonin, and C-reactive protein for sepsis identification: a systematic review and meta-analysis.

Ann Intensive Care 2019 Jan 8;9(1). Epub 2019 Jan 8.

Department of Emergency Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.

Background: Neutrophil CD64 is widely described as an accurate biomarker for the diagnosis of infection in patients with septic syndrome. We performed a systematic review and meta-analysis to evaluate the diagnostic accuracy of neutrophil CD64, comparing it with C-reactive protein (CRP) and procalcitonin (PCT) for the diagnosis of infection in adult patients with septic syndrome, based on sepsis-2 criteria. We searched the PubMed and Embase databases and Google Scholar. Read More

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http://dx.doi.org/10.1186/s13613-018-0479-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325056PMC
January 2019

High-flow oxygen therapy in tracheostomized patients at high risk of weaning failure.

Ann Intensive Care 2019 Jan 7;9(1). Epub 2019 Jan 7.

Dipartimento dell'Emergenza e Trapianti d'Organo (DETO), Sezione di Anestesiologia e Rianimazione, Università degli Studi di Bari "Aldo Moro", Ospedale Policlinico, Piazza Giulio Cesare 11, Bari, Italy.

Purpose: High-flow oxygen therapy delivered through nasal cannulae improves oxygenation and decreases work of breathing in critically ill patients. Little is known of the physiological effects of high-flow oxygen therapy applied to the tracheostomy cannula (T-HF). In this study, we compared the effects of T-HF or conventional low-flow oxygen therapy (conventional O) on neuro-ventilatory drive, work of breathing, respiratory rate (RR) and gas exchange, in a mixed population of tracheostomized patients at high risk of weaning failure. Read More

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http://dx.doi.org/10.1186/s13613-019-0482-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323064PMC
January 2019
4 Reads

Low-flow CO removal in combination with renal replacement therapy effectively reduces ventilation requirements in hypercapnic patients: a pilot study.

Ann Intensive Care 2019 Jan 7;9(1). Epub 2019 Jan 7.

Medical Intensive Care, Department of Cardiology, Klinikum Nuremberg, Paracelsus Medical University, Nuremberg, Germany.

Background: Lung-protective strategies are the cornerstone of mechanical ventilation in critically ill patients with both ARDS and other disorders. Extracorporeal CO removal (ECCOR) may enhance lung protection by allowing even further reductions in tidal volumes and is effective in low-flow settings commonly used for renal replacement therapy. In this study, we describe for the first time the effects of a labeled and certified system combining ECCOR and renal replacement therapy on pulmonary stress and strain in hypercapnic patients with renal failure. Read More

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http://dx.doi.org/10.1186/s13613-019-0480-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323065PMC
January 2019
3 Reads

Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study.

Ann Intensive Care 2019 Jan 5;9(1). Epub 2019 Jan 5.

Medical ICU, Saint-Louis Teaching Hospital, 1 Avenue Claude Vellefaux, 75010, Paris, France.

Background: Although outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQOL) in this population. We aim to assess post-intensive care unit (ICU) burden and HRQOL of critically ill patients with HMs and to identify risk factors for quality-of-life (QOL) impairment.

Results: In total, 1011 patients with HMs who required ICU admission in 17 ICUs in France and Belgium were included in the study; 278 and 117 patients were evaluated for QOL at 3 months and 1 year, respectively, after ICU discharge. Read More

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http://dx.doi.org/10.1186/s13613-018-0478-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320707PMC
January 2019
3 Reads

Driving pressure during proportional assist ventilation: an observational study.

Ann Intensive Care 2019 Jan 3;9(1). Epub 2019 Jan 3.

Department of Intensive Care Medicine, University Hospital of Heraklion, School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.

Background: During passive mechanical ventilation, the driving pressure of the respiratory system is an important mediator of ventilator-induced lung injury. Monitoring of driving pressure during assisted ventilation, similar to controlled ventilation, could be a tool to identify patients at risk of ventilator-induced lung injury. The aim of this study was to describe driving pressure over time and to identify whether and when high driving pressure occurs in critically ill patients during assisted ventilation. Read More

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http://dx.doi.org/10.1186/s13613-018-0477-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314935PMC
January 2019