918 results match your criteria Annals Of Clinical Psychiatry[Journal]


A focus on postpartum depression among African American women: A literature review.

Ann Clin Psychiatry 2019 Feb 1;30(1):e1-e6. Epub 2019 Feb 1.

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA. E-MAIL:

Background: Some studies have reported a higher rate of postpartum depression in African American vs White women. We reviewed the literature to identify the possible factors associated with a greater risk of postpartum depression in African American women.

Methods: A comprehensive literature review was conducted using journal databases such as PubMed and Google Scholar. Read More

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February 2019
1 Read

Intensity-dependent, disabling exercise-induced depression and irritability without primary mood disorder.

Ann Clin Psychiatry 2019 Feb;31(1):70-71

Department of Psychiatry and Health Behavior, Office of Academic Affairs, Medical College of Georgia, Augusta University, Augusta, GA 30912 USA. E-MAIL:

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February 2019
2.525 Impact Factor

Evidence for using PRN pharmacotherapy to treat undifferentiated acute agitation or aggression.

Ann Clin Psychiatry 2019 Feb;31(1):54-69

Chairman, Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio, 44307 USA. E-MAIL:

Background: This systematic review identified published studies that evaluated the use of (PRN) medication in patients with acute agitation or aggression of undifferentiated etiology.

Methods: A literature search was conducted of PubMed and MEDLINE for randomized controlled trials (RCTs) that evaluated the use of PRN medications for individuals with undifferentiated agitation or aggression. Bibliographic databases of published articles were also searched for additional studies. Read More

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February 2019
7 Reads

Schizoaffective disorder: A review.

Ann Clin Psychiatry 2019 Feb;31(1):47-53

University of Iowa Carver College of Medicine, Iowa City, IA 52242. E-MAIL:

Background: Schizoaffective disorder (SAD) is a chronic, potentially disabling psychotic disorder common in clinical settings. SAD often has been used as a diagnosis for individuals having an admixture of mood and psychotic symptoms whose diagnosis is uncertain. Its hallmark is the presence of symptoms of a major mood episode (either a depressive or manic episode) concurrent with symptoms characteristic of schizophrenia, such as delusions, hallucinations, or disorganized speech. Read More

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February 2019
2 Reads

Should childhood conduct disorder be necessary to diagnose antisocial personality disorder in adults?

Ann Clin Psychiatry 2019 Feb;31(1):36-44

University of Nebraska-Lincoln, Room 237, Burnett Hall. E-MAIL:

Background: Antisocial personality disorder (ASPD) is the only DSM personality disorder that requires a diagnosis of conduct disorder (CD) during childhood. Previous research comparing adults diagnosed with ASPD with adults who meet all ASPD criteria except for a history of CD (referred to in this study as adult antisocial syndrome [AAS]) have reported mixed results. This study sought to clarify the differences among adults with ASPD, adults with AAS, and a large psychiatric outpatient control group. Read More

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February 2019

E-cigarette use (vaping) is associated with illicit drug use, mental health problems, and impulsivity in university students.

Ann Clin Psychiatry 2019 Feb;31(1):27-35

Professor, Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, Chicago, IL 60637 USA. E-MAIL:

Background: This study examined the prevalence of e-cigarette use ("vaping") among university students and its associations with psychosocial correlates.

Methods: In this study, 9,449 students received a 156-item anonymous online survey assessed the use of e-cigarettes (ever or past year), alcohol and drug use, mental health issues, and impulsive and compulsive traits.

Results: In total, 3,572 university students (57. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420081PMC
February 2019
3 Reads

A prenatal supplement with methylfolate for the treatment and prevention of depression in women trying to conceive and during pregnancy.

Ann Clin Psychiatry 2019 Feb;31(1):4-16

Psychiatry Department, Ammon-Pinizzotto Center for Women's Mental Health, Massachusetts General Hospital, Boston, MA 02114 USA. E-MAIL:

Background: Women often seek antidepressant alternatives for major depressive disorder (MDD) in anticipation of or during pregnancy. In this preliminary study, EnBrace HR, a prenatal supplement containing methylfolate, was investigated for depressive relapse prevention and for acute treatment of MDD in women planning pregnancy or during pregnancy.

Methods: This 12-week open-label study included women with histories of MDD who were planning pregnancy or pregnant < 28 weeks. Read More

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February 2019

On communicating 'bad news'.

Authors:
Richard Balon

Ann Clin Psychiatry 2019 Feb;31(1):1-2

Departments of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University, Detroit, MI 48201 USA. E-MAIL:

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February 2019

Perceived sleep quality predicts cognitive function in adults with major depressive disorder independent of depression severity.

Ann Clin Psychiatry 2019 Feb;31(1):17-26

Mood Disorders, Psychopharmacology Unit, University Health Network, Toronto, ON, M5T 2S8 Canada, E-MAIL:

Background: The aim of this study was to examine the role of perceived sleep quality in predicting subjective as well as objective cognitive function in adults with major depressive disorder (MDD).

Methods: Adults with recurrent MDD (n = 100) experiencing a major depressive episode of at least moderate severity and age-, sex-, and education-matched healthy controls (HC) (n = 100) were recruited to participate in a clinical trial validating the THINC-integrated tool (THINC-it; NCT02508493) for cognitive function. The THINC-it includes subjective and objective measures of cognitive function. Read More

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February 2019
3 Reads
2.525 Impact Factor

Use of cariprazine in psychiatric disorders: A systematic review.

Ann Clin Psychiatry 2018 Nov;30(4):326-334

Chairman, Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio 44307 USA; E-MAIL:

Background: Cariprazine was approved for treating schizophrenia and bipolar disorder, and currently is being evaluated for treating depression in clinical trials in the United States. We systematically reviewed the literature on the efficacy and safety of cariprazine.

Methods: We performed a literature search of the PubMed, MEDLINE, PsycINFO, EMBASE, and Cochrane collaboration databases through August 31, 2016. Read More

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November 2018
2 Reads

Anticonvulsants as monotherapy or adjuncts to treat alcohol withdrawal: A systematic review.

Ann Clin Psychiatry 2018 Nov;30(4):312-325

Chairman, Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio 44307 USA; E-MAIL:

Background: This systematic review evaluates current literature on anticonvulsants to treat alcohol withdrawal symptoms (AWS).

Methods: We performed a literature search of PubMed, MEDLINE, PsycINFO, EMBASE, and Cochrane collaboration databases through September 30, 2016. The search was not restricted by patients' age. Read More

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November 2018
8 Reads

Sociodemographic and clinical correlates of the frequently hospitalized African American patients with severe and persistent mental illness.

Ann Clin Psychiatry 2018 Nov;30(4):305-310

Connecticut Mental Health Center, New Haven, CT 06519 USA, E-mail:

Background: Many researchers and clinicians are becoming increasingly concerned about the phenomenon of frequent psychiatric inpatient hospitalization in those with severe and persistent mental illness. This study aims to shed light on this occurrence in the African American psychiatric inpatient population by examining their sociodemographic and clinical correlates.

Methods: We retrospectively reviewed the medical charts of 39 African American patients who have had ≥3 inpatient psychiatric admissions in a year at Howard University Hospital, an urban, academically-affiliated hospital serving a predominantly African American population in Washington, DC. Read More

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November 2018
5 Reads
2.525 Impact Factor

Frequency of use and perceived helpfulness of wellness strategies for bipolar and unipolar depression.

Ann Clin Psychiatry 2018 Nov;30(4):296-304

Mood Disorders Psychopharmacology Unit, University Health Network,Toronto, ON M5T 2S8 Canada;E-mail:

Background: The majority of research in mood disorders has focused on pharmacologic, psychotherapeutic, and brain stimulation interventions. Conversely, the utility of less structured interventions, such as lifestyle modifications or wellness strategies, has remained understudied. The objective of the current study is to evaluate the frequency of use and perceived helpfulness of wellness strategies for bipolar and unipolar depression. Read More

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November 2018
3 Reads

Sexual behavior in patients with bipolar illness.

Ann Clin Psychiatry 2018 Nov;30(4):289-295

Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202 USA; E-mail:

Background: There is a dearth of information regarding sexual behavior in patients with bipolar illness.

Methods: A questionnaire regarding sexual and reproductive behavior was administered to all willing attendees of an academic bipolar clinic. Information regarding onset, maintenance, and nature of sexual behaviors, as well as marriage and children, was collected. Read More

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November 2018
1 Read

A longitudinal study of housing status and crime in a homeless population.

Ann Clin Psychiatry 2018 Nov;30(4):280-288

The Altshuler Center for Education and Research at Metrocare Services, Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390-8828 USA; E-mail:

Background: It is well established that homelessness is associated with crime. Previous research suggests that this association is at least partially secondary to homeless status offenses (eg, vagrancy and trespassing resulting from behaviors intrinsic to homelessness). To investigate this relationship, this study compared criminal behavior in a homeless population under housed and unhoused conditions. Read More

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November 2018
2 Reads

The impact of a psychosocial program on clinical outcomes for severe psychiatric disorders.

Ann Clin Psychiatry 2018 No;30(4):271-279

Department of Psychiatry Southern Illinois University School of Medicine, Springfield, IL 62794 USA; E-mail:

Background: This retrospective study evaluated the impact of a psychosocial program on individuals with severe and chronic psychiatric disorders. This study also examined potential modifiable predictors of hospitalization.

Methods: The sample was comprised of 94 individuals with severe and chronic mental illness who were followed in the Community Support Network (CSN), a psychosocial program. Read More

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October 2018
22 Reads

Interest among veterans in spiritually-oriented therapy for inner conflict/moral injury in the setting of PTSD.

Ann Clin Psychiatry 2018 Nov;30(4):262-270

Department of Psychiatry and Health Behavior, Office of Academic Affairs, Medical College of Georgia at Augusta University, Augusta, GA 30912 USA; E-mail:

Background: We examined U.S. veterans' interest in spiritually-oriented therapy (SOT) for treating inner conflict/moral injury (ICMI); identified combat-related, demographic, religious, and psychological characteristics of those interested in this treatment modality; and determined which participants would prefer SOT therapy. Read More

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November 2018
6 Reads
2.525 Impact Factor

Electronic medical records and the psychiatrist shortage

Ann Clin Psychiatry 2018 11;30(4):257-259

Department of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University School of Medicine, Detroit, MI, USA. E-mail:

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November 2018
2 Reads

The use of memantine in neuropsychiatric disorders: An overview.

Ann Clin Psychiatry 2018 Aug;30(3):234-248

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104 USA; E-MAIL:

Background: Memantine is a non-competitive N-methyl-d-aspartate receptor antagonist currently used for the treatment of Alzheimer's disease as an approved indication. However, as knowledge of signaling pathways is increasing, the therapeutic potential of memantine is being applied for the treatment of various psychiatric illnesses.

Methods: The PubMed online database was searched for the use of memantine in various psychiatric disorders. Read More

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August 2018
31 Reads

Empathy changes in neurocognitive disorders: A review.

Ann Clin Psychiatry 2018 Aug;30(3):220-232

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri 63104-1027 USA; E-MAIL:

Background: Empathy can be broadly defined as the ability to understand what others feel (cognitive empathy) and feel what others feel (affective empathy). The capacity to empathize may be impaired in certain major neurocognitive disorders (MNCDs), affecting not only the patient, but also the caregivers.

Methods: PubMed and Google Scholar databases were searched for studies investigating empathy changes, using an objective scale, in patients with MNCDs. Read More

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August 2018
3 Reads

Does diagnosing a patient with borderline personality disorder negatively impact patient satisfaction with the initial diagnostic evaluation?

Ann Clin Psychiatry 2018 Aug;30(3):215-219

Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI 02904 USA; E-MAIL:

Background: Research has found that clinicians have less sympathetic attitudes and behave less empathically toward patients with borderline personality disorder (BPD). Anecdotal conversations with clinicians and trainees reveal that some have a reluctance to tell their patients that they have BPD due to a concern that these patients will react badly. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project, we examined whether diagnosing BPD resulted in lower satisfaction with the initial evaluation. Read More

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August 2018
4 Reads

Depression and substance use disorders in the offspring of depressed parents as a function of the parent's borderline personality disorder symptomatology.

Ann Clin Psychiatry 2018 Aug;30(2):207-214

Department of Psychiatry, Rhode Island Hospital, Providence, RI 02903 USA; E-MAIL:

Background: Parental major depressive disorder (MDD) and borderline personality disorder (BPD) are associated with increased risk of offspring psychopathology. It is unclear whether BPD in depressed parents infers greater risk than depression alone. We hypothesized that BPD features in depressed parents would be associated with higher morbid risk of offspring MDD and substance use disorders (SUDs). Read More

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August 2018
2 Reads

Is ondansetron beneficial for psychosis associated with dementia?.

Ann Clin Psychiatry 2018 Aug;30(3):200-206

Department of Psychiatry, MetroHealth, Cleveland, Ohio 44109 USA; E-MAIL:

Background: This systematic review identified published studies that evaluated the use of ondansetron in individuals with psychosis associated with dementia.

Methods: A literature search was conducted of PubMed, MEDLINE, EMBASE, PsycINFO, and Cochrane Collaboration databases for randomized controlled trials (RCTs), cohort studies, and case reports that evaluated the use of ondansetron for individuals with psychosis associated with dementia. Bibliographic databases of published articles were also searched for additional studies. Read More

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August 2018
1 Read

Body temperature rises following improvement of depression with ECT.

Ann Clin Psychiatry 2018 Aug;30(3):196-199

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine, St. Louis, MO 63104 USA; E-MAIL:

Background: Recent studies have reported hyperthermia is an efficacious treatment for depression. Thus, we hypothesized that a proven depression therapy such as electroconvulsive therapy (ECT) would be associated with an increase in body temperature.

Methods: A retrospective chart analysis was conducted on 33 participants who recovered from depression after a course of ECT. Read More

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August 2018
1 Read

Academic skills in pediatric obsessive-compulsive disorder: A preliminary study.

Ann Clin Psychiatry 2018 Aug;30(3):185-195

BC Children's Hospital Research Institute, Vancouver, BC, V5Z 4H4 Canada; E-MAIL:

Background: Obsessive-compulsive disorder (OCD) is a prevalent and debilitating illness that often begins in childhood and has a significant impact on the functioning of youth and their families. Given that schooling represents a considerable portion of youth's lives and is a key contributor to their development, identifying impacts of OCD on school performance is important.

Methods: The present study evaluated academic skill differences in OCD-affected youth age 7 to 18 (n = 25) compared with matched healthy controls (HCs; n = 25), as captured via standardized testing. Read More

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August 2018
1 Read

What is the overlap between subjective and objective cognitive impairments in MDD?

Ann Clin Psychiatry 2018 Aug;30(3):176-184

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; E-MAIL:

Background: Cognitive impairments, such as memory deficits and executive impairment, are common among patients with major depressive disorder (MDD) and can be captured with objective or subjective assessments. The aim of this post-hoc analysis of the CONNECT study was to assess the degree of overlap between subjective and objective cognitive impairment among MDD patients, and to evaluate associated clinical characteristics.

Methods: The study was conducted from April 2012 to February 2014 and enrolled a total of 602 patients with MDD who reported subjective cognitive impairment. Read More

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August 2018
24 Reads

Experiences of gender incongruence and the relationship between social exclusion, psychological distress, and dysfunction among South African transgender adults: A field-study for ICD-11.

Ann Clin Psychiatry 2018 Aug;30(3):168-174

J Block, Groote Schuur Hospital, South Africa; E-MAIL:

Background: The classification of sexuality-related conditions and conditions relating to transgender identity has generated controversy. Growing evidence suggests that the distress and dysfunction reported by transgender individuals is more likely associated with social exclusion, stigmatization, and violence than as a result of gender incongruence per se. Our study aimed to explore the experiences of South African transgender individuals through: 1) their self-reported accounts of gender incongruence, and 2) associations between their experiences of social exclusion and violence, and their reports of psychological distress and dysfunction during adolescence. Read More

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August 2018
26 Reads
2.525 Impact Factor

The inexplicable rise of medication prices.

Authors:
Richard Balon

Ann Clin Psychiatry 2018 Aug;30(3):165-166

Department of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University School of Medicine, Detroit, MI, USA. E-mail:

Prescription medications are now the fastest-growing medical costs. Prices of brand name medications are exorbitant. An example is long-acting injectable aripiprazole, which costs more than $2,400 for a single injection in the United States, while in Canada this cost is less than $500 and in Turkey it is approximately $150. Read More

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August 2018
1 Read

Catatonia in the medically ill: Etiology, diagnosis, and treatment. The Academy of Consultation-Liaison Psychiatry Evidence-Based Medicine Subcommittee Monograph.

Ann Clin Psychiatry 2018 May;30(2):140-155

Rowan School of Osteopathic Medicine. Cherry Hill, NJ 08002 USA. E-MAIL:

Background: Catatonia in medically ill patients is rare but often unrecognized. This monograph summarizes current knowledge on the diagnosis, epidemiology, etiology, and management of catatonia occurring in the medical setting.

Methods: PubMed searches were used to identify relevant articles from 1962 to present. Read More

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May 2018
34 Reads

Exploring Asian American attitudes regarding mental health treatment in primary care: A qualitative study.

Ann Clin Psychiatry 2018 May;30(2):133-139

Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15217 USA. E-MAIL:

Background: In this exploratory study, we examined attitudes regarding mental health treatment among 10 Asian American patients in an urban primary care setting to better understand contextual barriers to care.

Methods: Ten semi-structured telephone interviews were conducted with Asian Americans recruited from primary care practices in an urban medical center.

Results: The study's qualitative data suggest that focusing on specific cultural concerns is essential for increasing mental health access for Asian Americans. Read More

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May 2018
4 Reads

AlzhaTV: A nonpharmacological intervention to manage behavioral and psychological symptoms in nursing home dementia patients.

Ann Clin Psychiatry 2018 May;30(2):122-132

AlzhaCare LLC. Rome, GA 30161 USA. E-MAIL:

Background: Currently, 5 million seniors who reside in the community or assisted living or nursing facilities are affected by Alzheimer's disease and other neurocognitive disorders. They experience various psychiatric symptoms. Also, their family members are stressed from caregiving, and may feel guilty for not doing more. Read More

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May 2018
2 Reads

Moral injury, posttraumatic stress disorder, and religious involvement among U.S. veterans.

Ann Clin Psychiatry 2018 May;30(2):113-121

Department of Psychiatry and Health Behavior, Office of Academic Affairs, Medical College of Georgia at Augusta University. Augusta, GA 30912 USA. E-MAIL:

Background: Traumatic experiences can cause ethical conflicts. "Moral injury" (MI) has been used to describe this emotional/cognitive state, and could contribute to the development of posttraumatic stress disorder (PTSD) or block its recovery. We examine the relationship between MI and PTSD, and the impact of religious involvement (RI) on that relationship. Read More

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May 2018
1 Read

Age at first sexual activity: Clinical and cognitive associations.

Ann Clin Psychiatry 2018 May;30(2):102-112

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine. Chicago, IL 60637 USA. E-MAIL:

Background: Engagement in sexual activity is common among adolescents and can be considered part of adolescent development, but it carries potential life-changing consequences.

Methods: This study examined if clinical and cognitive differences existed between adolescents who engaged in voluntary sexual behavior before age 15, between ages 15 to 18, and after age 18. All participants were part of a larger study examining impulsive behavior in young adults. Read More

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May 2018
4 Reads

Symptom severity and its clinical correlates in kleptomania.

Ann Clin Psychiatry 2018 May;30(2):97-101

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine. Chicago, IL 60637 USA. E-MAIL:

Background: Kleptomania (compulsive stealing) remains poorly understood, with limited data regarding its underlying pathophysiology and appropriate treatment choices.

Methods: Participants (N = 112) age 18 to 65 with a primary, current diagnosis of kleptomania were assessed for the severity of their stealing behavior and urges to steal, as well as related mental health symptoms. To identify clinical and demographic measures associated with variation in disease severity, we utilized the statistical technique of partial least squares. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935224PMC
May 2018
2 Reads

Effects of nonpharmacological therapies on anxiety and cortisol: A meta-analysis.

Ann Clin Psychiatry 2018 May;30(2):91-96

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University. St. Louis, MO 63118 USA. E-MAIL:

Background: Although pharmacotherapy is considered the standard of care for the treatment of anxiety, a subset of the patients remains resistant or intolerant to iatrogenic adverse effects. Nonpharmacological and nonpsychotherapeutic interventions, sometimes referred to as "complementary treatments," have emerged as possible alternatives in the treatment of anxiety. We conducted a meta-analysis of placebo-controlled studies to assess the efficacy of nonpharmacological therapy on anxiety. Read More

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May 2018
1 Read

Patient primary language in a culturally focused intervention for Latino Americans with depression.

Ann Clin Psychiatry 2018 May;30(2):84-90

Depression Clinical and Research Program. Massachusetts General Hospital. 1 Bowdoin Square, 6th Floor, Boston, MA, 02114 USA.

Background: This study examined whether a culturally focused psychiatric consultation program (CFP) for Latino Americans was equally effective in reducing depressive symptoms in English-speaking and Spanish-speaking patients.

Methods: The CFP utilizes the Engagement Interview Protocol (EIP), a semi-standardized protocol eliciting patient narratives about illness beliefs. The sample included 118 Latino American patients presenting with depressive symptoms. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223022PMC
May 2018
4 Reads
2.525 Impact Factor

The importance of paying attention to relationships.

Authors:
Richard Balon

Ann Clin Psychiatry 2018 May;30(2):81-82

Department of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University School of Medicine, Detroit, MI, USA. E-mail:

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May 2018
1 Read

Modafinil associated with new-onset obsessivecompulsive disorder.

Ann Clin Psychiatry 2018 Feb;30(1):70-71

Department of Psychiatry and Neuroscience, University of California, Riverside, School of Medicine, Riverside, CA 92507 USA. E-MAIL:

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February 2018
1 Read

Stuttering and levetiracetam: Case report and research proposal.

Ann Clin Psychiatry 2018 Feb;30(1):68-69

Instituto de Investigación Biosanitaria del Hospital Clínico San Carlos, Madrid, Spain. E-mail:

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February 2018

A brief history of polarity in mood and its diagnostic evolution.

Ann Clin Psychiatry 2018 Feb;30(1):61-66

Department of Psychiatry and Human Behavior, Medical College of Georgia at Augusta University, Augusta, GA 30912 USA. E-mail:

Background: We reviewed the historical development of diagnostic nomenclature and classification systems of mood disorders.

Methods: A literature search in PubMed and Google Scholar was performed using multiple search terms. Also, the criteria and classification of various mood disorders were reviewed and compared across all editions of DSM. Read More

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February 2018
84 Reads
2.525 Impact Factor

Effectiveness of mindfulness-based stress reduction in a community sample over 2 years.

Ann Clin Psychiatry 2018 Feb;30(1):52-60

Department of Psychology, New Mexico State University, Las Cruces, NM 88003 USA. E-MAIL:

Background: Although numerous studies have demonstrated that mindfulness-based stress reduction (MBSR) improves clinical and nonclinical outcomes, few studies have followed MBSR participants for >12 months, and few have analyzed post-intervention home practice.

Methods: We followed a community sample of 247 self-referred adults for 2 years after completion of an 8-week MBSR program. Dependent variables, including self-reported anxiety, depression, perceived wellness, mindfulness, and duration and frequency of continued home practice, were measured before and after the program and every 6 months after. Read More

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February 2018
1 Read

Determinants of cognitive function in individuals with type 2 diabetes mellitus: A meta-analysis.

Ann Clin Psychiatry 2018 Feb;30(1):38-50

Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada. E-mail:

Background: Type 2 diabetes mellitus (T2DM) is associated with deficits across multiple cognitive domains; however, the determinants of cognitive impairment in T2DM are not well characterized. We aimed to evaluate body mass index (BMI), glycemic control, and T2DM duration as moderators of cognitive dysfunction in T2DM.

Methods: We conducted a meta-analytic review of the literature reporting data on BMI, hemoglobin A1c (HbA1c), T2DM duration, and validated measures of processing speed (ie, Digit Symbol Substitution Test, Trail Making Test [TMT]-A), verbal learning and memory (ie, Rey Auditory Verbal Learning Test), and working memory/executive function (ie, TMT-B) among individuals with vs without T2DM. Read More

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February 2018
52 Reads
2.520 Impact Factor

Differences in the cognitive profile of depression between racial groups.

Ann Clin Psychiatry 2018 Feb;30(1):32-37

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, Chicago, IL 60637 USA. E-mail:

Background: There is little research concerning whether race is associated with different clinical presentations of psychiatric disorders. Understanding the racial aspects of cognitive differences among depressed adults could help identify specific targets for depression treatment.

Methods: We recruited 59 participants (52. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788274PMC
February 2018
3 Reads

Is binge eating a cognitive disorder? Results from the International Mood Disorders Collaborative Project.

Ann Clin Psychiatry 2018 Feb;30(1):25-31

University Health Network, Toronto, ON, Canada. E-mail:

Background: Individuals with binge eating disorder (BED) are differentially affected by attention-deficit/hyperactivity disorder (ADHD), obesity, and substance use disorder. We have investigated to what extent cognitive deficits are relevant to binge eating behavior (BEB).

Methods: Data from the International Mood Disorders Collaborative Project were retrospectively and cross-sectionally analyzed to compare individuals with and without BEB on measures of anhedonia and general cognitive functions (n = 566). Read More

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February 2018
25 Reads
2.520 Impact Factor

The association of adverse mental health effects with repeated exposure to disasters.

Ann Clin Psychiatry 2018 Feb;30(1):17-24

Department of Educational Psychology, Texas A&M University, College Station, TX 77843 USA. E-mail:

Background: It has been assumed that the mental health effects of repeated trauma should be incrementally greater than simple additive effects of separate trauma. However, repeated disasters afflicting the same population are uncommon. This study investigated psychiatric disorders following differential exposures to repeated disasters. Read More

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February 2018
2 Reads

Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

Authors:
Donald W Black

Ann Clin Psychiatry 2018 Feb;30(1):4-5

University of Iowa, Iowa City, IA, USA.

One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Read More

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February 2018

Are meta-analyses clinically useful?

Authors:
Richard Balon

Ann Clin Psychiatry 2018 Feb;30(1):1-2

Department of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University School of Medicine, Detroit, MI, USA. E-mail:

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February 2018
1 Read

Concomitant calcium channel blocker and antipsychotic therapy in patients with schizophrenia: Efficacy analysis of the CATIE-Sz phase 1 data.

Ann Clin Psychiatry 2018 02;30(1):6-16

Department of Clinical Sciences, Touro University California, College of Pharmacy, Vallejo, CA, USA. E-mail:

Background: This study evaluated the influence of concomitant calcium channel blocker (CCB) and antipsychotic (AP) therapy on efficacy measures in patients with schizophrenia.

Methods: Data from the Clinical Antipsychotic Trials of Intervention Effectiveness in Schizophrenia study were used to evaluate the effect of concomitant CCB therapy on the Clinical Global Impression-Severity (CGI-S) score, Positive and Negative Syndrome Scale (PANSS) score, and time to all-cause discontinuation of AP treatment. Concomitant treatment participants (CCB plus AP) were matched with controls (AP alone) by propensity scores using a 3:1 greedy match algorithm, then analyzed using a mixed linear effects model adjusted for fixed covariates. Read More

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February 2018
1 Read

Renal concerns relative to the use of lithium in geriatric bipolar disorder patients.

Ann Clin Psychiatry 2017 Nov;29(4):283-290

Department of Psychiatry and Behavioral Neuroscience, Saint Louis University, St. Louis, MO, USA. E-mail:

Background: Lithium is a first-line treatment for bipolar disorder in geriatric patients; however, it has long been associated with potentially significant renal consequences, including chronic kidney disease (CKD).

Methods: We reviewed the available evidence to characterize the effects of lithium on renal function, provide a consensus on periodic monitoring, and propose criteria for transitioning an older patient with bipolar disorder and renal issues to an alternate medication.

Results: Although the evidence on lithium use, duration, and dosage on progression of CKD and end-stage renal disease in geriatric patients is mixed, there is solid evidence that patients receiving lithium generally have a reduced glomerular filtration rate compared with controls. Read More

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November 2017
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Systematic review of recent guidelines for pharmacological treatments of bipolar disorders in adults.

Ann Clin Psychiatry 2017 Nov;29(4):266-282

Department of Psychiatry and Health Behavior, The Medical College of Georgia, Augusta University, Augusta, GA, USA. E-mail:

Background: To examine the similarities and differences among practice guidelines for managing bipolar disorders (BDs) in adults.

Methods: A literature search in PubMed/Medline was performed using multiple search terms and bibliographies for guidelines from July 2013 (since FDA approval of lurasidone) to June 2017.

Results: Six treatment guidelines for BDs in adults were identified. Read More

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November 2017
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