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Ann Dermatol Venereol 2019 Feb 11. Epub 2019 Feb 11.

Centre de simulation en santé All'Sims, CHU d'Angers, 4, rue Larrey, 49045 Angers cedex, France.

Ann Dermatol Venereol 2019 Feb 8. Epub 2019 Feb 8.

Département de dermatologie et unité Inserm U1058, hôpital Saint-Éloi, université Montpellier I, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 29. Epub 2019 Jan 29.

Unité de dermatologie interventionnelle, service de dermatologie, hôpital Saint-André, CHU de Bordeaux, 1, rue Jean-Burguet, 33000 Bordeaux, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 29. Epub 2019 Jan 29.

Unité Inserm U1058, département de dermatologie, université Montpellier, hôpital Saint-Éloi, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France. Electronic address:

Therapeutic progress in primary cutaneous lymphomas continues to be largely dominated by the T-cell lymphomas, towards which the great majority of recent therapeutic innovations have been directed. The latter include local treatments consisting either of relatively classical but "revamped" approaches involving different pharmaceutical forms (example: chlormethine gel) or else lower but seemingly equally effective dosages (electron therapy), or of more innovative approaches (example: UVA-1, dynamic phototherapy, imiquimod, resimiquimod). However, significant progress has been made chiefly in terms of systemic treatments with the emergence of "targeted" drugs that directly and specifically target tumour cells (monoclonal antibodies directed against CD30, CCR4 or CD158k) and the further development of "small" molecules such as histone deacetylase inhibitors and new cytostatics. Read More

Ann Dermatol Venereol 2019 Jan 29. Epub 2019 Jan 29.

Service de dermatologie, CHR Metz-Thionville, 1, allée du Château, CS 45001, 57085 Metz cedex 03, France. Electronic address:

The porphyrias are a group of metabolic disorders resulting from an innate abnormality in haem biosynthesis, and the clinical settings of which vary according to the genetic enzyme abnormality in question. These are genetic disorders with autosomal dominant or recessive inheritance of varying penetrance, and whose clinical expression differs according to the preferential location of haem precursors. Different classifications have been proposed according to genetic inheritance, the enzyme anomaly at issue, and clinical expression. Read More

Ann Dermatol Venereol 2019 Jan 28. Epub 2019 Jan 28.

Service de médecine vasculaire, groupe hospitalier Paris Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France.

Background: Topical chlormethine has been widely used in the early stages of mycosis fungoides for many years. Cutaneous reactions (skin irritation and itch) are the most frequent adverse effects. Herein we report a rare side effect: severe necrotic leg ulcers. Read More

Ann Dermatol Venereol 2019 Jan 28. Epub 2019 Jan 28.

Service de dermatologie, CHRU de Lille, hôpital Claude-Huriez, rue Michel-Polonowski, 59000 Lille, France; Université de Lille, 59000 Lille, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 28. Epub 2019 Jan 28.

Département de santé publique, CHU d'Ambroise-Paré, Assistance publique-hôpitaux de Paris, 9, avenue Charles de Gaulle, 92104 Boulogne-Billancourt cedex, France.

Background: Methotrexate (MTX) is a major systemic treatment for moderate to severe plaque psoriasis. A randomized trial has recently been published evaluating a single weekly dosage (17.5mg), but few prospective real-life data are available. Read More

Ann Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Service de dermatologie-infectiologie, CHI Fréjus Saint-Raphaël, 240, avenue de Saint-Lambert, 83600 Fréjus, France.

Background: Toxic shock syndrome (TSS) was first described by Todd in 1978. The relevant Lancet publication reported 7 cases of children with fever, exanthema, hypotension and diarrhoea associated with multiple organ failure. An association between TSS and use of hyper-absorbent tampons in menstruating women was discovered in the 1980s. Read More

Ann Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Service de dermatologie, CHU Hedi Chaker, 3029 Sfax, Tunisie.

Background: Epidermal cyst is a common cutaneous lesion that may be located in the scrotum and is seen especially in young and middle-aged men. This entity is not only chronic but can also affect the patient's appearance, thus having an impact on their quality of life. Surgical excision is the classical procedure to remove such cysts, but it can be time-consuming and leave unpleasant scars. Read More

Ann Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Service de dermatologie et centre expert sur le prurit, CHU, 2, avenue Foch, 29200 Brest, France; Laboratoire sur les interactions épithéliums-neurones (LIEN-EA4685), université de Bretagne occidentale, 29200 Brest, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Clinique dermatologique, université de Strasbourg, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France.

Introduction: Basaloid follicular hamartoma (BFH) is a rare tumor first described in 1985. It bears clinical and histologic similarities with basal cell carcinoma (BCC), in particular the so-called infundibulocystic form. We performed a single-center clinicopathological study of a series of typical cases of this entity that is occasionally difficult to diagnose. Read More

Ann Dermatol Venereol 2019 Jan 17. Epub 2019 Jan 17.

Service de dermatologie, hôpital universitaire de Saint-Étienne, 42055 Saint-Étienne cedex 2, France.

Ann Dermatol Venereol 2019 Jan 10. Epub 2019 Jan 10.

Dermatologie, université Cheikh Anta Diop de Dakar, hôpital Aristide le Dantec de Dakar, Dakar, Sénégal.

Objective: To determine the epidemiological and etiological profile of tinea capitis in adults in Dakar (Senegal).

Patients And Methods: A 9-month prospective, multicenter, descriptive and analytic study. Patients included were aged over 18 years. Read More

Ann Dermatol Venereol 2019 Jan 9;146(1):75-81. Epub 2019 Jan 9.

Cabinet de dermatologie, 49, rue Hoche, 92130 Issy-les-Moulineaux, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 9;146(1):37-40. Epub 2019 Jan 9.

Service de dermatologie, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.

Background: Median raphe cysts are rare benign lesions of the male genitalia. They may be present along the entire raphe, from the urethral meatus to the anus, in the median position. We report herein a case of median raphe cyst with an atypical clinical and histological presentation. Read More

Ann Dermatol Venereol 2019 Jan 9. Epub 2019 Jan 9.

Service de néonatologie et réanimation néonatale, CHU Hassan II, Fès, Maroc.

Adams-Oliver syndrome (AOS) is a congenital condition characterized by congenital aplasia cutis and transverse limb defects. Herein we report a case of an infant with severe intra-uterine growth restriction presenting AOS associated with cutis marmorata telangiectatica but with no other organ complications. The outcome was complicated by hemorrhagic and septic shock, which resulted in the death of the infant in a setting of multiorgan failure. Read More

Ann Dermatol Venereol 2019 Jan 9;146(1):9-18. Epub 2019 Jan 9.

Service de dermatologie et allergologie, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; Inserm U1135, Cimi-Paris, centre d'immunologie et de maladies infectieuses, 75013 Paris, France.

Objective: Assessment of the efficacy and safety of omalizumab in chronic urticaria refractory to conventional treatment (H1-antihistamines at high dosage and montelukast) in real-life practice.

Patients And Methods: A retrospective, descriptive, single-centre study was performed of the data for all patients presenting refractory chronic spontaneous urticaria or inducible urticaria and receiving omalizumab (300mg every four weeks) from November 2012 to June 2016.

Results: In all, 23 patients were included. Read More

Ann Dermatol Venereol 2019 Jan 8. Epub 2019 Jan 8.

Service de dermatologie, université catholique Lille, hôpital Saint-Vincent de Paul, boulevard de Belfort - BP 387, 59020 Lille cedex, France.

Background: Tularaemia is a zoonotic disease caused by inoculation with the Gram-negative coccobacillus Francisella tularensis. It was first described in the United States in 1911 and is a rare disease with an annual reported incidence in France between 2002 and 2012 of 0.07 cases per 100,000 habitants. Read More

Ann Dermatol Venereol 2019 Jan 28;146(1):82-85. Epub 2018 Dec 28.

Service de dermatologie, hôpital Claude-Huriez, CHU de Lille, rue Michel-Polonowski, 59037 Lille cedex, France; Université de Lille, 59037 Lille, France.

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS63-VIS100

Clinique dermatologique, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS4-VIS13

Service de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67094 Strasbourg Cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS27-VIS62

Bibliothèque Henri-Feulard, hôpital Saint-Louis, Paris, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS20-VIS26

Médecin des hôpitaux, vice-président de la Société française d'histoire de la dermatologie Centre clinique et biologique des MST, hôpital Saint-Louis AP-HP, 42, rue Bichat, 75010 Paris, France; Service de dermatologie, groupe hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS154-VIS155

Service de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67094 Strasbourg Cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS150-VIS153

Médecin consultant. Service de dermatologie du Pr Vincent Descamps, hôpital Bichat-Claude-Bernard, AP-HP, Université Denis-Diderot, Paris 7, 46, rue Henri-Huchard, 75877 Paris Cedex 18, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS14-VIS19

Service de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67094 Strasbourg Cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS139-VIS149

Professeur Émérite à l'université de Tours, 114 rue de Boisdenier 37000 Tours, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS137-VIS138

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS127-VIS136

Service de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67094 Strasbourg Cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS122-VIS126

Service de dermatologie, AP-HP, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS116-VIS121

Service de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, BP 426, 67094 Strasbourg Cedex, France. Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS101-VIS115

1, Chemin Tony Garnier 69120 Vaulx en Velin « J'espère que le vent qui vient de Lyon va nous apporter de la graine pour le jardin des annales » (lettre de Besnier à Doyon du 22/12/79). Electronic address:

Ann Dermatol Venereol 2018 Dec;145 Suppl 6:VIS1-VIS3

Département de dermatologie des Cliniques Universitaires Saint-Luc, 1200 Bruxelles, Belgique. Electronic address:

Ann Dermatol Venereol 2019 Jan 28;146(1):19-25. Epub 2018 Dec 28.

Dermatology clinic, université de Strasbourg, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.

Background: Antisynthetase antibodies (ASA) are directed against aminoacyl-tRNA-synthetases, ubiquitous enzymes of which eight types have hitherto been described. They are seen primarily in antisynthetase syndrome (ASS), in which diffuse interstitial lung disease is associated with inflammatory myopathy, joint involvement and cutaneous signs, in particular mechanic's hands. The aim of this study was to determine the prevalence and semiological characteristics of cutaneous involvement in patients presenting ASA. Read More

Ann Dermatol Venereol 2018 Sep;145 Suppl 4:IVS3-IVS90

Bibliothèque Henri-Feulard, hôpital Saint-Louis, Paris. Electronic address:

In 1866, Alphonse Devergie, physician supported by Armand Husson, manager of the Assistance publique created a permanent exhibition of teaching images of skin diseases at the Hôpital Saint-Louis (Paris). Twenty-five years later the initiative was made concrete by the inauguration of a building housing a museum, a medical library and rooms for outpatients. Enriched by the works of dermatologists, moulageurs - mainly Jules Baretta -, painters and photographs the museum became worldwide renown exhibiting the largest wax moulages collection of the world. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS47-VIIS55

Service de dermatologie, Hôpital Bichat, université Paris 7, Paris, France. Electronic address:

The therapeutic revolution in the management of inflammatory dermatoses is under way. The therapeutic arsenal is expanding in the field of psoriasis, including biologics (TNF blockers, anti-IL12/IL23, anti-IL17, and anti-IL23 antibodies), new small molecules (tyrosine kinase inhibitor), and a new biologic for generalized pustular psoriasis (anti-IL36 receptor). New biologics will be soon available in the field of atopic dermatitis in addition to anti-IL4/IL13 antibodies. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS40-VIIS46

Chef du service de dermato-oncologie et INSERM U 981, Gustave-Roussy, université Paris-Sud, Le Kremlin-Bicêtre, France. Electronic address:

This year again, several breaking news were published in our field of oncodermatology, especially in the domain of immunotherapy. Many works have reported results on predictive biomarker identification. Concerning melanoma treatment, we were disappointed by the negative results of the phase III trial evaluating the IDO1 inhibitor epacadostat + pembrolizumab versus pembrolizumab. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS32-VIIS46

Service de dermatologie, centre de référence des maladies rares de la peau, université Paul-Sabatier, CHU Larrey, 24, chemin de Pouvourville, TSA 40031, 31059 Toulouse, Cedex 09, France. Electronic address:

In order to describe the latest news in Pediatric dermatology (pathophysiology, clinical aspects and therapy), a literature review was performed from September 2017 to September 2018. This article is not an exhaustive review but present the new data that may infuence the daily practice. The results are presented by disease that may be common or rare. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS24-VIIS31

Service de dermatologie, hôpital Saint-André, CHU de Bordeaux, 1, rue Jean-Burget, 33000 Bordeaux, France. Electronic address:

What's new in internal medicine will be dedicated to three topics: i) inflammatory myopathies constituting a heterogenous group of diseases whose clinical manifestations, immunological abnormalities, treatment response and outcomes vary widely; ii) alterations of gut microbiota contributing to the occurrence or development of a range of conditions, including autoimmune diseases for which further work is necessary to understand the correlation of dysbiosis with these diseases; iii) the reciprocal relationship between obesity, metabolic syndrome, atherosclerosis and autoimmune diseases. New data concerning systemic sclerosis, cutaneous vasculitis, adult Still's disease, autoantibodies anti DFS70, Epstein Barr virus and autoimmune diseases were also highlighted. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS17-VIIS23

Centre de référence des dermatoses bulleuses auto-immunes et centre de référence des maladies génétiques à expression cutanée, service de dermatologie, hôpital Avicenne, AP-HP, 125, rue de Stalingrad, 93000 Bobigny ; INSERM UMR 1125, université Paris 13, 74, rue Marcel Cachin, 93000 Bobigny, France. Electronic address:

A traditional lecture given during the annual meeting of the French Society of Dermatology in Paris summarizes the highlights of the scientific literature over the past year. In the current article the selection of the 2017-2018 period retains the following areas of interest: role of microbiome in the response to anti-PD-1 and in autoimmunity, PI3Kδ inhibitors in autoimmune bullous diseases, diagnostic and therapeutic applications of CRISPR/Cas, arrival of CAR-T cells therapy into clinical practice, gene therapy successes, use of targeted therapies in genodermatoses and integration of genetics in primary care. © 2018 Elsevier Masson SAS. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS11-VIIS16

Dermatologue libérale, 30, rue des Clercs, 57000 Metz, France, présidente du Groupe de dermatologie esthétique et correctrice (gDEC) de la Société française de dermatologie, past présidente de l'Association de dermatologie esthétique et laser de l'Est (ADELE). Electronic address:

This year, many publications have focused on understanding, avoiding and treating vascular complications when injecting fillers. New protocols for the use of hyaluronidase have shown their effectiveness in preventing skin necrosis or blindness after vascular embolism when injecting hyaluronic acid. Other areas of interventional dermatology have been well documented: myomodulation is an interesting concept that describes the impact of the injection depth of a filler on muscle forces in order to correct the balances between the lowering and elevators during congenital or acquired defcits with aging. Read More

Ann Dermatol Venereol 2018 Dec;145 Suppl 7:VIIS1-VIIS10

Service de dermatologie, hôpital Louis-Pasteur, 68024 Colmar cedex, France. Electronic address:

In this article, we performed a review of all new data of clinical relevance for the dermatologists that were published in the medical literature between September, 2017 and September, 2018. Besides advances that will be useful in day-to-day dermatological practice, we intended to give a more general perspective to this review by taking into account certain international health issues that might in final concern each of us in a globalized world. Focus were more particularly done on the following topics: infectious diseases (including sexually transmitted infections), neglected tropical diseases, adverse effects of drugs, bullous diseases, allergology, wound healing, dermatology on black skin, and public health dermatology. Read More

Ann Dermatol Venereol 2018 Dec 20. Epub 2018 Dec 20.

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Electronic address:

Background: Herein we present a case of palmoplantar keratoderma (PPK) in a young adopted girl of Chinese origin living in France.

Observation: The patient, aged six years, had presented transgressive PPK since birth, as well as erythema progressing in congestive inflammatory episodes, palmoplantar hyperhidrosis and progressive characteristics (moderate hyperkeratosis in areas of rubbing other than the palms and soles, namely the elbows and knees). Histopathological examination of a skin biopsy revealed a thick epidermis with lengthening and thickening of crests. Read More

Ann Dermatol Venereol 2019 Jan 20;146(1):41-74. Epub 2018 Dec 20.

101, boulevard du Président Wilson, 33200 Bordeaux, France. Electronic address:

Correction of cutaneous and facial ageing is the key reason for consultations in aesthetic dermatology. This demand on the part of patients, which has become a social phenomenon, has increased thanks to the remarkable progress made in nonsurgical and less invasive therapies such as lasers, botulinum toxin and fillers. But in order to optimise their use and to provide a personalised touch, since each face ages differently, an overall facial analysis, both static and dynamic, is essential. Read More

Ann Dermatol Venereol 2019 Jan 15;146(1):26-30. Epub 2018 Dec 15.

Dermatology Department, Nantes University Hospital, CRCINA, CIC 1413, université de Nantes, 44093 Nantes, France.

Since its discovery, Propionibacterium acnes has undergone various name changes, and has been known since 2016, as Cutibacterium acnes. Herein we set out the history and rational of these taxonomic changes together with a description of a new genus, Cutibacterium, which includes five species within the cutaneous ecosystem. Modern microbiological techniques allow finer distinction between species and subspecies while also enabling the identification of separate subtypes within the population of Cutibacterium acnes. Read More

Ann Dermatol Venereol 2018 Dec 14. Epub 2018 Dec 14.

56, boulevard Saint-Marcel, 75005 Paris, France. Electronic address:

Ann Dermatol Venereol 2019 Jan 5;146(1):1-3. Epub 2018 Dec 5.

2, rue du cherche-midi 75006 Paris, France.

Ann Dermatol Venereol 2018 Dec 6. Epub 2018 Dec 6.

Hôpital gynéco-obstétrique et pédiatrique de Yaoundé, Yaoundé, Cameroun; Faculté de médicine et des sciences biomédicales, université de Yaoundé, Yaoundé, Cameroun.

Ann Dermatol Venereol 2018 Nov;145 Suppl 5:VS36-VS41

Université Paris-7, service de dermatologie, hôpital Saint-Louis, Paris, France. Electronic address:

Until recently, advanced BCC were only accessible to a highly morbid surgery not necessarily proving to be carcinologic, and leaving terrible dysmorphic sequelae hard to accept by the patient. Another possibility, the only one in case of metastatic BCC, was chemotherapy which efficacy has never been proven in a clinical trial. Radiotherapy is most often not accessible because of previous radiotherapy or because of the localization or the extension of the lesion. Read More