5,771 results match your criteria Annales de biologie clinique[Journal]


Do liquid wastes from automated instruments in medical laboratories have their proper microbicide effect?

Ann Biol Clin (Paris) 2019 Apr 12. Epub 2019 Apr 12.

Laboratoire de virologie, Institut des agents infectieux, Groupement Hospitalier Nord des Hospices civils de Lyon, Lyon, France, Institut des sciences biologiques et pharmaceutiques de Lyon, Université Claude Bernard Lyon 1, Lyon, France, CIRI, Centre international de recherche en infectiologie, Équipe Virpath, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École normale supérieure de Lyon, Lyon, France.

Liquid wastes from clinical biology automated systems are currently evacuated in the urban network after chemical treatment to eliminate a possible risk of infection. Since these wastes are ecotoxic because of the presence of numerous chemical reagents, we studied their intrinsic microbicidal power towards a selection of infectious agents widely found in clinical specimens. The objective was to determine if an additional anti-infectious treatment before elimination is necessary. Read More

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http://dx.doi.org/10.1684/abc.2019.1431DOI Listing
April 2019
1 Read

Cytomegalovirus cholestasis in an immunocompetent host.

Ann Biol Clin (Paris) 2019 Apr 12. Epub 2019 Apr 12.

Université Mohammed V, Faculté de médecine et de pharmacie de Rabat, Centre Hospitalier Universitaire Ibn Sina, Hôpital des spécialités, Laboratoire central de virologie, Rabat, Maroc.

Primary infection or reactivation of cytomegalovirus (CMV) can induce in immunocompromised patients a severe disease depending on the type of immuno-suppression, and can affect multiple organs. On the other hand, the infection is benign and mostly asymptomatic in immunocompetent individuals who do not require antiviral treatment. Rare cases of primary infection have been documented. Read More

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http://dx.doi.org/10.1684/abc.2019.1434DOI Listing
April 2019
1 Read

Transudative myelomatous pleurisy revealing pleural localization of primary plasma cell leukemia.

Ann Biol Clin (Paris) 2019 Mar 25. Epub 2019 Mar 25.

Laboratoire d'hématologie, CHU Mohammed VI, Oujda, Maroc, Faculté de médecine et de pharmacie, Université Mohammed Premier, Oujda, Maroc.

Primary plasma cell leukemia (PPCL) is an aggressive and rare variant of multiple myeloma (MM), with frequent extramedullary involvement, mainly liver and splenic lesions. Pleuropulmonary involvement has rarely been described in the literature. We report a case of primary plasma cell leukemia in a 46-year-old patient, whose first symptom was pleural effusion with mediastinal adenopathies simulating a pleural localization of a lymphomatous process. Read More

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http://dx.doi.org/10.1684/abc.2019.1420DOI Listing
March 2019
4 Reads

7q22 deletion in myeloid malignancies: be attentive to the design of the FISH probe.

Ann Biol Clin (Paris) 2019 Mar 25. Epub 2019 Mar 25.

Institut universitaire du cancer Toulouse - Oncopole, Toulouse, France.

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http://dx.doi.org/10.1684/abc.2019.1425DOI Listing

B-cell non-Hodgkin lymphoma discovery after observation of a platelet satellitism around atypical lymphocytes.

Ann Biol Clin (Paris) 2019 Mar 25. Epub 2019 Mar 25.

Laboratoire d'hématologie, CHR d'Orléans, France.

We report the case of an 83-year-old woman admitted to the accident and emergency unit for pneumopathy. The blood cell count on the DXH automaton (Coulter® ™ UniCel® DxH) found a normochromic and normocytic anemia, anormal platelet count and subnormal leukocyte formula. The only alarm raised by the automaton was the presence of a basocytosis. Read More

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http://dx.doi.org/10.1684/abc.2018.1406DOI Listing
March 2019
3 Reads

Acquired hemophilia A associated with bullous pemphigoid and multiple myeloma: a case report.

Ann Biol Clin (Paris) 2019 Mar 11. Epub 2019 Mar 11.

Service d'hématologie-immunologie-transfusion, Hôpitaux Universitaires Paris Ile-de-France Ouest, CHU Ambroise Paré, Boulogne-Billancourt, France.

Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disorder caused by circulating autoantibodies directed against factor (F) VIII. Apart from idiopathic cases, AHA is associated with autoimmune diseases, cancers, use of medications, pregnancy and the post-partum period. We report the case of a 78-year-old a male patient presenting with symptoms of a hematoma after a fall three days previously. Read More

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http://dx.doi.org/10.1684/abc.2018.1405DOI Listing
March 2019
2 Reads

Brain abscess caused by Streptococcus intermedius: a case report.

Ann Biol Clin (Paris) 2019 Mar 11. Epub 2019 Mar 11.

Laboratoire de bactériologie-virologie, Hôpital militaire Avicenne, Marrakech, Maroc.

Streptococcus intermedius is considered as a commensal of the oropharynx, but can be a source of serious infections. We report a case of cerebral abscess in a young man of 18 years, who was admitted to the emergency room for consciousness disorder, and whose cerebral CT showed a frontal mass evoking the diagnosis of abscess. Diagnosis was confirmed by bacteriological examination of puncture fluid which was in favor of Streptococcus intermedius abscess. Read More

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http://dx.doi.org/10.1684/abc.2019.1421DOI Listing
March 2019
1 Read

Plasmatic neuroglobin during the primitive open-angle glaucoma.

Ann Biol Clin (Paris) 2019 02;77(1):99-105

Département de chimie-biochimie, Faculté de médecine et des sciences de la santé, Libreville, Gabon.

Objective: Elucidate the relation between neuroglobin and the primitive open-angle glaucoma.

Patients And Methods: This cross-sectional case-control study involved 64 patients with primitive open-angle glaucoma on 2 eyes and 64 control subjects. Glaucoma was classified as early, moderate or severe according to ophthalmological examination. Read More

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http://dx.doi.org/10.1684/abc.2018.1408DOI Listing
February 2019

Which sample for the transport of mycoplasma, eSwab® or dry swab?

Ann Biol Clin (Paris) 2019 02;77(1):95-98

Laboratoire de virologie, Institut des agents infectieux (IAI) de Lyon, Centre de biologie et de pathologie Nord, Groupement hospitalier Nord, Centre hospitalier universitaire de Lyon, Lyon, France.

Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU), belonging to mycoplasmas, are implicated in genital and urinary infections. These bacteria are extremely sensitive to environmental factors but remain detectable by culture methods. This study aimed to compare performance of detection on samples performed on eSwab or dry swabs. Read More

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http://dx.doi.org/10.1684/abc.2018.1407DOI Listing
February 2019
1 Read

Analysis and management of the pre-analytical risks in hemostasis.

Ann Biol Clin (Paris) 2019 02;77(1):87-94

Laboratoire d'hématologie, CHU Ibn Rochd, Casablanca ; Université Hassan II, Casablanca, Maroc.

Risk analysis consists in identification, scoring and ranking of risks in order to manage the major risks. The aim of the study is to determine the risk analysis of the pre-analytical step of routine hemostasis in Hematological laboratory of CHU Ibn Rochd-Casablanca, Morocco.

Material And Methods: The identification of pre-analytical activities of routine hemostasis was extensively realized according to a "by-proccess" methodology. Read More

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http://dx.doi.org/10.1684/abc.2019.1410DOI Listing
February 2019

Saving patient blood: a new rule of life? Focus on pre-operative anemia.

Authors:
Katell Peoc'h

Ann Biol Clin (Paris) 2019 02;77(1):7-9

UF de biochimie clinique, Hôpital Beaujon, AP-HP, HUPNVS, UFR de médecine Xavier Bichat, Université Paris-Diderot, Paris, France, Comité scientifique de la Société française de biologie clinique, France.

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http://dx.doi.org/10.1684/abc.2019.1417DOI Listing
February 2019
1 Read

Prevalence of albuminuria in sickle cell disease patients at the Campus university hospital of Lome, Togo.

Ann Biol Clin (Paris) 2019 02;77(1):79-86

Faculté des sciences, Université de Lomé, Lomé, Togo.

Objectives: The objective of this study was to assess the prevalence of albuminuria in sickle cell disease patients at the Campus University Hospital of Lome.

Patients And Method: Albuminuria was assessed by the urinary albumin-to-creatinine ratio (UACR) in sickle cell disease individuals who attended the outpatient consultation in their steady state.

Results: The prevalence of albuminuria was 21% (14/67). Read More

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http://dx.doi.org/10.1684/abc.2018.1404DOI Listing
February 2019
5 Reads

Le mot de la rédactrice en chef.

Ann Biol Clin (Paris) 2019 02;77(1)

Rédactrice en chef.

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http://dx.doi.org/10.1684/abc.2019.1416DOI Listing
February 2019

Les vœux du président de la SFBC.

Authors:
Vincent Sapin

Ann Biol Clin (Paris) 2019 02;77(1)

Président de la SFBC.

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http://dx.doi.org/10.1684/abc.2019.1415DOI Listing
February 2019

Factor VIII assays in treated hemophilia A patients.

Ann Biol Clin (Paris) 2019 02;77(1):53-65

CHU Lille, Institut d'hématologie-transfusion, Inserm U1011, Lille, France.

Replacement therapy with plasma-derived or recombinant FVIII (pdFVIII or rFVIII) concentrates is the standard of treatment in patients with hemophilia A. The reference method used for measuring factor VIII (FVIII:C) levels in patients treated by FVIII concentrates is the chromogenic substrate assay (CSA). However, the one-stage clotting assay (OSA) is predominantly used in current clinical practice, but this method depends on the activated partial thromboplastin time (APTT) reagent and the coagulation analyzer used, and wide variations in the measurements of FVIII recovery have been reported with some factor concentrates. Read More

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http://dx.doi.org/10.1684/abc.2019.1413DOI Listing
February 2019
1 Read

Factor IX assays in treated hemophilia B patients.

Ann Biol Clin (Paris) 2019 02;77(1):41-52

Service d'hématologie hémostase, Hospices civils de Lyon, Bron, France.

Replacement therapy with plasma-derived or recombinant FIX (pdFIX or rFIX) concentrates is the standard of treatment in patients with hemophilia B. The method predominantly used for measuring factor IX (FIX:C) levels is the one-stage clotting assay (OSA) but this method depends on the activated partial thromboplastin time (APTT) reagent and the coagulation analyzer used, and wide variations in the measurements of FIX recovery have been reported with some factor concentrates. The French study group on the biology of hemorrhagic diseases (a collaborative group of the GFHT and MHEMO network), presents a review of the literature and proposals for the monitoring of FIX:C levels in treated hemophilia B patients. Read More

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http://dx.doi.org/10.1684/abc.2019.1414DOI Listing
February 2019
2 Reads

Proteinuria in pediatrics: from screening to diagnosis and monitoring of kidney disease.

Ann Biol Clin (Paris) 2019 02;77(1):36-40

Service de néphrologie pédiatrique, CHU Arnaud de Villeneuve - Université de Montpellier, France.

The incidental finding of a proteinuria is a common cause of consultation in pediatric nephrology. Although it is transient in most cases, it may also be indicative of a kidney disease. For this reason, a moderate proteinuria in children should not be overlooked. Read More

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http://dx.doi.org/10.1684/abc.2019.1411DOI Listing
February 2019
1 Read

Interest of albuminuria in nephrology, diabetology and as a marker of cardiovascular risk.

Ann Biol Clin (Paris) 2019 02;77(1):26-35

Laboratoire de biochimie, CHU de Bordeaux, Bordeaux, France, Résonance magnétique des systèmes biologiques UMR5536 CNRS Université Bordeaux, Bordeaux, France.

Albuminuria is associated with the progression of chronic kidney disease and the occurrence of cardiovascular events in patients with and without diabetes. The evolution of albuminuria appears to be associated with patient's prognosis. How exactly microalbuminuria is linked to cardiovascular risk remains unclear. Read More

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http://dx.doi.org/10.1684/abc.2018.1402DOI Listing
February 2019
1 Read

Proteinuria typing: how, why and for whom?

Ann Biol Clin (Paris) 2019 02;77(1):13-25

Laboratoire de biochimie, Institut fédératif de biologie, CHU Purpan, Toulouse, France.

The typing of proteinuria is one of the complementary examinations carried out during the exploration of proteinuria. It aims to separate and identify the different proteins, or fractions of proteins, that make up proteinuria. The nature and relative importance of the proteins present reflect the location of the renal involvement and help to determine the etiology. Read More

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http://dx.doi.org/10.1684/abc.2018.1401DOI Listing
February 2019
1 Read

28 Journées du Collège national de biochimie des hôpitaux Paris, 24 et 25 janvier 2019.

Ann Biol Clin (Paris) 2019 02;77(1):116-120

Président du CNBH.

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http://dx.doi.org/10.1684/abc.2019.1418DOI Listing
February 2019

Erythrocytes morphology in pregnancy.

Ann Biol Clin (Paris) 2019 02;77(1):113-115

Service d'hématologie biologique, CHRU Nancy, France.

Morphologic anomalies of the red blood cells (RBCs) during pregnancy are poorly known. Peripheral blood films from 69 healthy pregnant women were investigated for shape, color and content anomalies of the RBCs. A range of minor alterations was observed, without clinical significance. Read More

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http://dx.doi.org/10.1684/abc.2018.1409DOI Listing
February 2019

IgD-λ multiple myeloma with excessive excretion of free light chains: a diagnostic trap in the identification of monoclonal gammopathies.

Ann Biol Clin (Paris) 2019 02;77(1):107-111

Service de biochimie clinique, Hôpital Arrazi, Centre hospitalier universitaire Mohammed VI, Marrakech, Maroc.

Immunoglobulin D multiple myeloma (IgD MM) is a rare entity of monoclonal gammopathies. We report the case of a IgD MM, associated with excessive excretion of lambda free light chains (FLL λ) diagnosed and managed at the University Hospital Mohammed VI of Marrakech among an adult hospitalized in the hematology department for bone pain and alteration of the general condition. Indeed, IgD MM is characterized by its clinical severity and poor prognosis. Read More

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http://dx.doi.org/10.1684/abc.2018.1403DOI Listing
February 2019

Proteinuria prescription in 2019.

Ann Biol Clin (Paris) 2019 02;77(1):10-12

Département de biochimie-hormonologie, CHU de Montpellier, France.

Today, medical prescriptions of proteinuria or albuminuria, which are depending on medical status of patients, still depend on doctors. Indeed, according to their medical specialty or to the recommendations they are following, they could prescribe either proteinuria or albuminuria. The consequences are practical for laboratories and economical for patients and doctors. Read More

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http://dx.doi.org/10.1684/abc.2019.1412DOI Listing
February 2019
4 Reads

Strategies of neutralization of the direct oral anticoagulants effect: review of the literature.

Ann Biol Clin (Paris) 2019 02;77(1):67-78

Service d'hématologie biologique, CHU Pontchaillou, Rennes, France, CIC-Inserm 1414, Université de Rennes 1, France.

Many neutralizing agents of anticoagulant effect of factor Xa or thrombin inhibitors (xabans and dabigatran, respectively) have been developed since the commercialization of direct oral anticoagulants (DOAC) in 2008. Idarucizumab is a specific antidote of dabigatran commercialised since 2016. An antidote of xabans, andexanet-α, was very recently approved by the Food and Drug Administration (FDA). Read More

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http://dx.doi.org/10.1684/abc.2018.1400DOI Listing
February 2019

Lu pour vous dans….

Authors:

Ann Biol Clin (Paris) 2018 Dec;76(6):719-720

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http://dx.doi.org/10.1684/abc.2018.1386DOI Listing
December 2018

Determination of acceptable limits of precision parameters for lymphocyte count by flow cytometry.

Ann Biol Clin (Paris) 2018 Dec;76(6):687-693

Laboratoire d'immunologie, CHU de Nice, France.

Performance of lymphocyte count by flow cytometry is difficult to evaluate because of the lack of desirable range for precision performance. The aim of this work was to propose recommendations for acceptable precision variability. Data of repeatability and reproducibility of two levels of IQC were collected from sixty-four laboratories. Read More

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http://dx.doi.org/10.1684/abc.2018.1397DOI Listing
December 2018

A story of oedemas.

Ann Biol Clin (Paris) 2018 Dec;76(6):681-685

Laboratoire de biochimie, Hôpital Saint-Philibert, Lomme, France.

The Waldmann's disease is a primitive intestinal lymphangectasia. This exsudative enteropathy initiates a protein leakage by the digestive tract. Clinically, this syndrome is characterised by oedemas and biologically by hypoprotidemia and loss of lymphocytes T CD4+, which increases a risk for infections. Read More

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http://dx.doi.org/10.1684/abc.2018.1398DOI Listing
December 2018

Alagille syndrome: a case report.

Ann Biol Clin (Paris) 2018 Dec;76(6):675-680

Département de biochimie et génétique, CHU Angers, France.

We report the case of an infant hospitalized for neonatal anoxic ischemia in whom the diagnosis of Alagille syndrome (SAG ; MIM # 118450) was suspected in the presence of major cholestasis, cardiac malformations, suggestive facial dysmorphia, and vertebral and ocular abnormalities. This diagnosis was later confirmed by the detection of a heterozygous pathogenic variant in the gene JAG1, i.e. Read More

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http://dx.doi.org/10.1684/abc.2018.1399DOI Listing
December 2018

Relevance of total PSA and free PSA prescriptions.

Ann Biol Clin (Paris) 2018 Dec;76(6):659-663

Service de biochimie clinique et génétique, CHU Créteil, AP-HP, France.

The total PSA testing has been frequently criticized for its effectiveness in the early detection of prostate cancer. These widely resumed in and out of the medical community have led to a decrease in prescriptions. Recommendations against the use of PSA for screening have been issued in France and in most countries. Read More

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http://dx.doi.org/10.1684/abc.2018.1392DOI Listing
December 2018

Diagnostic workup in front of an adult neutropenia.

Ann Biol Clin (Paris) 2018 Dec;76(6):651-658

Service de médecine interne, Centre hospitalier de Royan, Vaux-sur-mer, France, Groupement de coopération sanitaire de Saintonge, Laboratoire inter-hospitalier de biologie médicale, Centres hospitaliers de Saint-Jean-d'Angély, Saintes, Royan et Jonzac, Saint-Jean-d'Angély.

Adult neutropenia, defined as a blood neutrophil count below 1.5 G/L, is a common condition. The most common cause of acute neutropenia is a drug-related reaction or an acute infectious disease. Read More

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http://dx.doi.org/10.1684/abc.2018.1393DOI Listing
December 2018
1 Read

Urinary protein or albumin/creatinin ratio for reporting measurements results.

Ann Biol Clin (Paris) 2018 Dec;76(6):643-650

Département de biochimie et hormonologie, CHU de Montpellier, France.

Urinary proteins or urinary albumin exhibit a high intra individual variability. Therefore, urine collected during 24 hours has been recognized as a reference biological fluid for usual values determination. However, urine collection during a day is difficult and numerous studies have been performed to replace the "gold standard" with measures on random samples and results given as protein/creatinine ratio or albumin/creatinine ratio, to decrease the variability. Read More

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http://dx.doi.org/10.1684/abc.2018.1394DOI Listing
December 2018

Urinary proteins: up-to-date reference methods for urinary protein analysis.

Ann Biol Clin (Paris) 2018 Dec;76(6):638-642

Laboratoire national de métrologie et d'essais, Paris, France.

Measurement of urine albumin has been introduced in the new classification of kidney disease (KD) as a marker for detecting, monitoring and predicting KD. Currently, the measure is not standardized. The variability of results obtained with commercially available procedures is important and can lead to misclassification of patients. Read More

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http://dx.doi.org/10.1684/abc.2018.1391DOI Listing
December 2018

Urinary albumin measurement methods.

Ann Biol Clin (Paris) 2018 Dec;76(6):633-637

Laboratoire de biochimie et biologie moléculaire, GH Sud Hospices civils de Lyon, France.

The quantification of urine albumin is a common practice in Medical Biology laboratories. It allows the assessment of renal injury in common pathologies and many studies have confirmed its role in the diagnosis and prognosis of these disorders. The physicochemical characteristics of albumin in the urine, very different from those in the blood, do not allow the use of the same standardized assay techniques for the blood albumin determination and make it difficult its quantification. Read More

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http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ab
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http://dx.doi.org/10.1684/abc.2018.1390DOI Listing
December 2018
8 Reads

Quantitative measurement of urinary proteins in 2018: advantages, disadvantages, limits.

Ann Biol Clin (Paris) 2018 Dec;76(6):627-631

Laboratoire de biochimie, Centre hospitalier universitaire de Nantes, France.

Today, there is no reference method for the measurement of urinary proteins. The difficulties are that urine is a very complex biological fluid, and that there are a high intra-and inter-individual variability in the protein excretion rate. Progress has been made during the last thirty years, but high analytical variability persists among the colorimetric or turbidimetric methods used for urinary proteins measurement. Read More

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http://dx.doi.org/10.1684/abc.2018.1389DOI Listing
December 2018

Urinary strips for proteins: easy to do but difficult to read!

Ann Biol Clin (Paris) 2018 Dec;76(6):617-626

Université de Liège, Service de chimie médicale, CHU Sart Tilman (CHU ULg), Liège, Belgique.

Urine is an easily accessible biological fluid. This availability makes it tempting for a direct analysis of urinary parameters by physicians. Urinary proteins, that are interesting markers for several pathologies, are detected by urinary strips, rapidly and at a low cost. Read More

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http://dx.doi.org/10.1684/abc.2018.1388DOI Listing
December 2018
2 Reads

Preanalytical step of urinary protein measurement: from urine sampling to preparation for analysis of the specimen.

Ann Biol Clin (Paris) 2018 Dec;76(6):609-616

Laboratoire de biochimie, CHU de Toulouse, France.

The preanalytical phase is a key step in urinary protein measurement. It is a complex step, which includes urine sampling, storage and transport to the laboratory and preparation for analysis of the specimen. It can lead to numerous errors, since urine sampling is made by the patient himself. Read More

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http://dx.doi.org/10.1684/abc.2018.1387DOI Listing
December 2018
2 Reads

Urinary protein measurement in 2018: don't make this practice banal.

Ann Biol Clin (Paris) 2018 Dec;76(6):607-608

Département de biochimie et hormonologie, CHU Lapeyronie, Montpellier, France.

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http://dx.doi.org/10.1684/abc.2018.1396DOI Listing
December 2018
1 Read

Robert Leluc (1928-2018).

Authors:

Ann Biol Clin (Paris) 2018 Dec;76(6):605

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http://dx.doi.org/10.1684/abc.2018.1395DOI Listing
December 2018

In vitro medical devices: how businesses can successfully comply with the new European regulation.

Ann Biol Clin (Paris) 2018 Dec;76(6):716-718

Maetrics, BioCity Nottingham, Pennyfoot Street, Nottingham, Royaume-Uni.

The European parliament finally approved the new European in vitro diagnostic regulation (IVDR) on 5 April 2017. This new regulation is shaking up the industry as it has a wider scope than its predecessor, meaning manufacturers of in vitro diagnostic medical devices must revise their compliance strategies exhaustively. In order to help manufacturers begin the process of compliance, this article highlights the principal changes in the regulation, providing a starting point for industry players. Read More

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http://dx.doi.org/10.1684/abc.2018.1369DOI Listing
December 2018

Immunoanalytical profile of thyroglobulin antibodies.

Authors:
Radhouene Doggui

Ann Biol Clin (Paris) 2018 Dec;76(6):695-704

Institut national de nutrition et de technologie alimentaire, Laboratoire de surveillance et épidémiologie nutritionnelles en Tunisie (LR12SP05), Tunis, Tunisie.

The anti-thyroglobulin autoantibodies are endogenous molecules directed against specific epitopes of thyroglobulin. These antibodies are linked to the autoimmune diseases or the differentiated thyroid cancer. The occurrence of anti-thyroglobulin autoantibodies may introduce inaccuracies in thyroglobulin quantification, causing over- or underestimation depending on the used method. Read More

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http://dx.doi.org/10.1684/abc.2018.1383DOI Listing
December 2018
7 Reads

Hepcidin: immunoanalytic characteristics.

Ann Biol Clin (Paris) 2018 Dec;76(6):705-715

CHU de Montpellier, Institut de médecine régénératrice et de biothérapies (IRMB), Laboratoire de biochimie-protéomique clinique, CCBHM, Hôpital Saint Eloi, Montpellier, France, Faculté de médecine, Université de Montpellier, France, Inserm U1040, Montpellier, France.

Hepcidin has progressively become essential in clinical practice for the diagnosis and follow-up of a large spectrum of diseases. Anyway, its own biochemical and structural characteristics have complicated and delayed the acquisition of a standardized quantifying tool of the peptide. Read More

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http://dx.doi.org/10.1684/abc.2018.1382DOI Listing
December 2018
3 Reads

How to manage chickenpox during pregnancy: case reports.

Ann Biol Clin (Paris) 2018 Dec;76(6):669-674

Consultation obstétrique, Hospices civils de Lyon, Groupement hospitalier Est, Lyon, France.

Chickenpox is a human infection that occurs mainly during childhood. Infection during pregnancy is therefore rare but may cause a congenital infection with malformation in less than 1% of cases. A specific management should be proposed at diagnosis in order to reduce materno-fetal transmission and morbimortality. Read More

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http://dx.doi.org/10.1684/abc.2018.1385DOI Listing
December 2018
3 Reads

IgG lymphoplasmacytic lymphoma: a case report.

Ann Biol Clin (Paris) 2018 Dec;76(6):665-668

Laboratoire d'hématologie, CHU de Toulouse, IUC-T, Toulouse, France.

Lymphoplasmacytic lymphoma is rare. Although most cases of LPL are Waldenström macroglobulinemia associated with an immunoglobulin M, there are exceptions. Indeed, few cases are immunoglobulin A-secreting or immunoglobulin G-secreting. Read More

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http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ab
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http://dx.doi.org/10.1684/abc.2018.1384DOI Listing
December 2018
5 Reads

7 symposium « Biologie d'urgence et gaz du sang ».

Ann Biol Clin (Paris) 2018 Oct;76(5):579-599

Service de biochimie, Hôpital Cochin, AP-HP, Paris et Faculté de Pharmacie, Université René Descartes, Paris, France.

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http://dx.doi.org/10.1684/abc.2018.1371DOI Listing
October 2018

IgM Myeloma: case report and literature review.

Ann Biol Clin (Paris) 2018 Oct;76(5):575-578

GCS de Saintonge, Centres hospitaliers de Saint-Jean-d'Angély, Jonzac, Saintes et Royan, Saint-Jean-d'Angély, France.

The presence of serum monoclonal IgM is often associated with the diagnosis of Waldenström macroglobulinemia (WM) or other chronic lymphoproliferative disorders. IgM myeloma is a rare entity (0.5%). Read More

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http://dx.doi.org/10.1684/abc.2018.1380DOI Listing
October 2018
7 Reads

Evaluation of the capillary assay of C-reactive protein (CRP) through the lenght of consultation in pediatric emergencies and its economic impact.

Ann Biol Clin (Paris) 2018 Oct;76(5):545-552

Service de biochimie et génétique moléculaire, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Fever is a frequent reason for consultation in pediatric emergency departments and raises the question of biological and radiological examinations. Rapidly obtaining the result of C-reactive protein (CRP) level is essential in front of the steady increase of the number of visits. We carried out a prospective study within the pediatric emergency department of the University Hospital of Clermont-Ferrand from January to April 2017, in order to evaluate the interest of the capillary CRP in point of care (POCT). Read More

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http://dx.doi.org/10.1684/abc.2018.1378DOI Listing
October 2018
2 Reads

Which are the significance of low level of glycated hemoglobin A1c?

Ann Biol Clin (Paris) 2018 Oct;76(5):531-536

Service de biochimie, Centre Hospitalier et Universitaire de Caen, Caen, France.

Glycated hemoglobin A1c (HbA1c) reflects the mean blood glucose over the lifespan of red blood cells and has become a valuable tool both for diagnosis and monitoring of diabetes. Nevertheless, some factors may under-estimate the HbA1c value, compromising its application. The aim of this retrospective study was to evaluate the incidence rate of HbA1c lower than 4% and to identify some clinical and biological factors that can potentially reduce the HbA1c level. Read More

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http://dx.doi.org/10.1684/abc.2018.1373DOI Listing
October 2018
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Evaluation of the effect of hemolysis, bilirubin, lipemy, glucosis and natrium on mean concentration of hemoglobin (XN 2000 Sysmex).

Ann Biol Clin (Paris) 2018 Oct;76(5):524-530

Laboratoire de biologie médicale, Hôpital d'instruction des armées Clermont Tonnerre, Brest, France.

We evaluated the effect of haemolysis, bilirubin, lipemia, hyperglycemia and natremia on mean corpuscular haemoglobin concentration (MCHC) measured by XN 2000 (Sysmex). Our evaluation had shown than correction is necessary for haemolysis and lipemia but not for icterus. There were not possible to reproduce variation of MCHC with hyperglycemia or variation of natremia. Read More

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http://dx.doi.org/10.1684/abc.2018.1376DOI Listing
October 2018
65 Reads

Development of digital PCR molecular tests for clinical practice: principles, practical implementation and recommendations.

Ann Biol Clin (Paris) 2018 Oct;76(5):505-523

Assistance publique - Hôpitaux de Marseille, Service d'anatomie pathologique et neuropathologie, Marseille, France, ID Solutions, Grabels, France.

Digital PCR (dPCR) is a 3rd generation technology that complements traditional end-point PCR and real-time PCR. It was developed to overcome certain limitations of conventional amplification techniques, in particular for the detection of small amounts of nucleic acids and/or rare variants. This technology is in a full swing because of its high sensitivity and major applications in various domains such as oncology, transplantation or non-invasive prenatal testing. Read More

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http://dx.doi.org/10.1684/abc.2018.1372DOI Listing
October 2018
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How I do in front of an hemolytic anemia of unknown etiology?

Ann Biol Clin (Paris) 2018 Oct;76(5):493-503

Groupement de coopération sanitaire de Saintonge, Centres hospitaliers de Saintes et Royan, Vaux-sur-mer, France, Service de médecine interne, Centre hospitalier de Royan, Vaux-sur-mer, France.

The most frequent causes of hemolytic anemias are immune or infectious diseases, drug induced hemolysis, thrombotic microangiopathies, hereditary spherocytosis, glucose-6-phosphate dehydrogenase or pyruvate kinase deficiencies, thalassemia's and sickle cell disease. Sometimes no cause is found because a rarer etiology is involved. The goal of this review is to remember some unfrequent constitutional or acquired causes and to point out difficulties to avoid wrong interpretations of analysis results. Read More

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http://dx.doi.org/10.1684/abc.2018.1381DOI Listing
October 2018
14 Reads