5,889 results match your criteria Annales de biologie clinique[Journal]


Leptin, adiponectin, lipodystrophic and severe insulin resistance syndromes.

Ann Biol Clin (Paris) 2020 May 15. Epub 2020 May 15.

Sorbonne Université, Inserm UMR_S 938, Centre de recherche Saint-Antoine, Institut hospitalo-universitaire de cardio-métabolisme et nutrition (ICAN), Paris, France, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Antoine, Centre national de référence des pathologies rares de l'insulino-sécrétion et de l'insulino-sensibilité (PRISIS), Service d'endocrinologie, diabétologie et endocrinologie de la reproduction, Paris, France, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Antoine, Laboratoire commun de biologie et génétique moléculaires, Paris, France.

Leptin and adiponectin are two adipokines currently used as biomarkers for diagnostic orientation and phenotyping in syndromes of lipodystrophy and severe insulin resistance. The level of these biomarkers also has an impact on the therapeutic management of the patients. These aspects, as well as our experience as a reference center, are described in this brief overview. Read More

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http://dx.doi.org/10.1684/abc.2020.1551DOI Listing

Effects of leptin and adiponectin on the cardiovascular system.

Ann Biol Clin (Paris) 2020 May 15. Epub 2020 May 15.

Sorbonne Université, Inserm UMR_S 938, Centre de recherche Saint-Antoine, Institut hospitalo-universitaire de cardio-métabolisme et nutrition (ICAN), Paris, France, Hôpital Tenon, AP-HP, Service de biochimie et hormonologie, UF Bio-marqueurs inflammatoires et métaboliques, Paris, France, Hôpitaux universitaires Henri Mondor, AP-HP, Département de biochimie-pharmacologie-biologie moléculaire-génétique médicale, Créteil, France.

Elevated circulating leptin levels have been associated with an increased cardiovascular risk in humans. However, recent meta-analyses show that certain epidemiological studies did not find this association, suggesting distinct effects of leptin depending on the pathophysiological context. Studies performed in mice deficient in leptin or in leptin receptors are often contradictory, showing both protective and deleterious effects of leptin. Read More

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http://dx.doi.org/10.1684/abc.2020.1548DOI Listing

Performance criteria for the verification of IgE and tryptase assay methods: recommendations from the AllergoBioNet network.

Ann Biol Clin (Paris) 2020 May 15. Epub 2020 May 15.

Aix Marseille Univ, IRD, APHM, MEPHI, IHU Méditerranée Infection, Marseille, France.

Accreditation of an in vitro diagnostic assay according to the NF/EN/ISO 15189 standard requires to analyze its technical performance before implementation for routine use, and annually when reviewing effectiveness of quality controls. Performance is evaluated through repeatability, intermediate fidelity, accuracy and uncertainty of measurement. The coefficients of variation (CV) of the intra-assay and inter-assay precision tests must be compared with those of "peers" (results from laboratories employing the same method) and also with those obtained with "all methods", i. Read More

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http://dx.doi.org/10.1684/abc.2020.1549DOI Listing

The adiponectin to leptin ratio, a still unrecognized biomarker of insulin resistance and cardiometabolic risk.

Ann Biol Clin (Paris) 2020 May 15. Epub 2020 May 15.

Sorbonne Université, Inserm UMR_S 938, Centre de recherche Saint-Antoine, Institut hospitalo-universitaire de cardio-métabolisme et nutrition (ICAN), Paris, France, Hôpital Tenon, AP-HP, Service de biochimie et hormonologie, UF Bio-marqueurs inflammatoires et métaboliques, Paris, France, Hôpitaux universitaires Henri Mondor, AP-HP, Département de biochimie-pharmacologie-biologie moléculaire-génétique médicale, Créteil, France.

Leptin and adiponectin are two adipokines. Their circulating concentrations, high for leptin and low for adiponectin, are predictive of insulin resistance and of an unfavorable cardiometabolic evolution in patients with obesity, metabolic syndrome or type 2 diabetes. In addition, recently, the adiponectin/leptin ratio has been proposed as an index of adipose tissue dysfunction together with threshold values for cardiometabolic risk for this index. Read More

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http://dx.doi.org/10.1684/abc.2020.1559DOI Listing

Hereditary pyropoïkilocytosis diagnosis in an infant: benefit of histograms and peripheral smear review.

Ann Biol Clin (Paris) 2020 May 15. Epub 2020 May 15.

Service d'hématologie biologique, CHU de Rouen, Rouen, France.

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http://dx.doi.org/10.1684/abc.2020.1552DOI Listing

Lu pour vous dans….

Authors:

Ann Biol Clin (Paris) 2020 Apr;78(2):223-224

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http://dx.doi.org/10.1684/abc.2020.1536DOI Listing

Haemodialysis Tunisian patient with acquired factor V inhibitor associated to arteriovenous shunt thrombosis.

Ann Biol Clin (Paris) 2020 Apr;78(2):206-209

Laboratoire d'hématologie, Hôpital Aziza Othmana, Tunis, Tunisie, Université El Manar, Faculté de médecine, Tunis, Tunisie.

Factor V deficiency is a rare hemostatic disorder. It may present with a diverse spectrum of symptoms due to a variety of mechanisms including development of autoantibodies associated with a number of conditions. We report a first case of factor V deficiency in Tunisian hemodialysis patient due to an autoantibody most likely secondary to antibiotic exposure responsible for an arteriovenous shunt thrombosis rather than bleeding. Read More

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http://dx.doi.org/10.1684/abc.2020.1540DOI Listing

Association of markers of rheumatoid arthritis in lupus. Is it a rhupus?

Ann Biol Clin (Paris) 2020 Apr;78(2):201-205

Unité d'immunologie, CHU de Blida, Algérie, Département de médecine, Faculté de médecine, Université de Blida 1, Algérie.

Anti-citrullinated cyclic peptide antibodies (ACPA) were initially considered very specific for the diagnosis of rheumatoid arthritis (RA), and can predict the prognosis of the disease. However, these antibodies can be detected in other autoimmune diseases, including systemic lupus erythematosus (SLE), the most common manifestation of which is inflammatory arthritis, which is often found in early-stage rheumatoid arthritis. The aim of our study is to evaluate the prevalence of ACPA antibodies and to analyze the profiles of their associations with autoantibodies specific to lupus, in order to look for a possible rhupus overlap syndrome in our patients. Read More

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http://dx.doi.org/10.1684/abc.2020.1518DOI Listing

Discrepancies in FVII:C levels depending on the thromboplastin: about a case.

Ann Biol Clin (Paris) 2020 Apr;78(2):198-200

Service d'hématologie biologique, Centre de biologie et de pathologie Est, Hospices civils de Lyon, France, Unité d'hémostase clinique, Hôpital cardiologique Louis Pradel, Hospices civils de Lyon, France.

Factor VII deficiency is the most common of the rare coagulation deficiencies. A hemorrhagic syndrome may occur in patients with FVII deficiency below 20%, although no correlation exist between the plasma FVII activity level (FVII:C) and the bleeding risk. Therefore, the management of surgery in patients with FVII deficiency remains challenging. Read More

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http://dx.doi.org/10.1684/abc.2020.1545DOI Listing

Benefit of Howell-Jolly bodies detection: finding of an acquired hyposplenism in a patient with Goodpasture syndrome.

Ann Biol Clin (Paris) 2020 Apr;78(2):191-194

Service d'hématologie biologique, CHU de Rouen, Rouen, France.

Howell-Jolly bodies are intraerythrocytic inclusions corresponding to a small portion of chromatin. Red blood cells that contain these nuclear remnants are removed from the circulation by the spleen. In most cases, presence of Howell-Jolly bodies on a blood smear is the result of functional asplenia and splenectomy. Read More

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http://dx.doi.org/10.1684/abc.2020.1544DOI Listing

Acute myeloid leukemia with inversion of chromosome 16: cytological, immunophenotypic and cytogenetic disruption.

Ann Biol Clin (Paris) 2020 Apr;78(2):187-190

Laboratoire d'hématologie, CHU Ibn Rochd, Casablanca, Maroc.

Acute myeloid leukemia (AML) with inv(16) is primarily associated with the eosinophilic LAM4 form belonging to the favorable prognosis group of AML. We report the case of an 18-year-old man with acute myeloid leukemia with unusual inversion of chromosome 16. Cytological, phenotypic and cytogenetic investigations showed a divergence from those in the literature. Read More

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http://dx.doi.org/10.1684/abc.2020.1542DOI Listing

Value of the syndromic approach for the diagnosis of an imported case of cholera.

Ann Biol Clin (Paris) 2020 Apr;78(2):181-186

Laboratoire Laborizon Maine Anjou, Le Mans, France.

A 70-year-old woman with no relevant medical history presented banal clinical signs of infectious gastroenteritis on her return from a trip to the Republic of the Union of Myanmar. The appearance of her stools and clinical findings were not suggestive of a typical case of cholera, but Vibrio cholerae was nevertheless isolated from her stools in the laboratory. The National reference center (NRC) for vibrios and cholera identified a Vibrio cholerae serogroup O1 (serotype Inaba) strain. Read More

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http://dx.doi.org/10.1684/abc.2020.1539DOI Listing

Primary breast tuberculosis in a man: a case report.

Ann Biol Clin (Paris) 2020 Apr;78(2):177-180

Service des maladies infectieuses et tropicales, Centre hospitalier national universitaire de Fann, Dakar, Sénégal.

The breast tuberculosis accounts for 0.06 to 0.1% of extra-pulmonary localizations. Read More

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http://dx.doi.org/10.1684/abc.2020.1537DOI Listing

INR and vitamin K antagonists management by the primary care physicians in Normandy.

Ann Biol Clin (Paris) 2020 Apr;78(2):157-173

Département de médecine générale, Université de Caen Normandie, Caen, France.

The main objective of our study was to carry out a statement of the knowledge and the management of the VKA by the General Practitioners (GPs) of Normandy and to evaluate their experience of the use of DOA with a questionnaire; 471 of the 1951 GPs requested responded. When the INR was stable in a patient affected with atrial fibrillation, the GPs participating dosed it again 4 weeks later, modified the dosage when the INR was below 1.9 or upper 3. Read More

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http://dx.doi.org/10.1684/abc.2020.1543DOI Listing

Analytical validation of a quantitative method for therapeutic drug monitoring on the Alinityc Abbott.

Ann Biol Clin (Paris) 2020 Apr;78(2):147-155

Toxicology Department, University Hospital, Liege, Belgium.

Objective: The aim of this study was to evaluate the analytical performance of the Alinityc Abbott compared to the Architect immunoassay system for the determination of drugs having a narrow therapeutic index.

Methods: Valproic acid, amikacin, gentamicin, phenobarbital and vancomycin were analyzed using Particle-Enhanced Turbidimetric Inhibitor Immunoassay (Petinia), phenytoin and theophylline were analyzed using an immunoenzymatic method and a colorimetric method was performed to quantify lithium. The methods were validated according to the total error approach. Read More

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http://dx.doi.org/10.1684/abc.2020.1535DOI Listing

Contamination of urine collected for cytobacteriological examination: situation in a university hospital in Morocco.

Ann Biol Clin (Paris) 2020 Apr;78(2):139-146

Université Mohammed Premier, Oujda, Maroc ; Faculté de médecine et de pharmacie, Laboratoire de microbiologie, Centre Hospitalier Universitaire Mohammed VI, Oujda, Maroc.

The pre-analytical step of the cytobacteriological examination of urine (CBEU) is one of the most critical in microbiology. The objectives of our study were to determine the rate of urinary contamination and to analyze the factors that would facilitate this in order to propose solutions to this problem.

Method: This is a 26-month descriptive study including all CBEU requests to our laboratory. Read More

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http://dx.doi.org/10.1684/abc.2020.1538DOI Listing
April 2020
0.415 Impact Factor

Sensing of blood glucose by the nervous system: why, where, how?

Authors:
Gilles Mithieux

Ann Biol Clin (Paris) 2020 Apr;78(2):134-138

Institut national de la santé et de la recherche médicale, U1213, Lyon, France, Université de Lyon, Lyon, France, Université Lyon I, Villeurbanne, France.

Maintaining plasma glucose concentration is a critical requirement for the body, making the detection of blood glucose by the nervous system essential. The reason generally given is that glucose is the main source of energy for living cells. In fact, other reasons make that glucose is so crucial. Read More

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http://dx.doi.org/10.1684/abc.2020.1531DOI Listing

Éditorial.

Ann Biol Clin (Paris) 2020 Apr;78(2):125

Rédactrice en chef.

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http://dx.doi.org/10.1684/abc.2020.1546DOI Listing

Autoantibody profile in a cohort of Algerian patients with systemic sclerosis.

Ann Biol Clin (Paris) 2020 Apr;78(2):126-133

Beni Messous University Hospital, Department of immunology ; Algiers Faculty of medicine, University of Algiers 1, Algiers, Algeria.

Aim: To describe the autoantibody profile in a cohort of Algerian patients with systemic sclerosis (SSc) and to determine clinical associations between SSc-related autoantibodies, disease subtypes and specific clinical features.

Methods: Consecutive Algerian patients with SSc were included in the present study. In addition to clinical characterization, all subjects underwent autoantibody testing using indirect immunofluorescence, immunoenzymatic, and line immunoblot assays. Read More

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http://dx.doi.org/10.1684/abc.2020.1532DOI Listing
April 2020
0.415 Impact Factor

Tricks and misuses of rapid diagnostic testing for malaria diagnosis.

Ann Biol Clin (Paris) 2020 Apr;78(2):174-176

Service de parasitologie-mycologie-médecine tropicale, CHU de Tours, France.

Molecular biology or immunochromatographic tests are conventionally offered as aids in the routine diagnosis of malaria. However, the interpretation of their results requires a precise knowledge of their limits, both by the biologist and the physician. It is in particular conditioned by thorough interview of the patient in order to seek a history of recent or even older malaria disease. Read More

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http://dx.doi.org/10.1684/abc.2020.1533DOI Listing

Thrombosis revealing POEMS syndrome. About a case.

Ann Biol Clin (Paris) 2020 Apr;78(2):195-197

Service de médecine interne, Groupement hospitalier Nord, Hôpital Croix-Rousse, Hospices civils de Lyon, France, Université Claude Bernard Lyon 1, Hesper EA 7425, Lyon, France.

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes) is a rare paraneoplastic disorder due to an underlying plasma cell dyscrasia. The diagnosis of POEMS syndrome requires a chronic polyneuropathy and a monoclonal lambda plasma cell-proliferative disorder (mandatory criteria), and various systematic symptoms such as sclerotic bone lesions, Castleman's disease, organomegaly, endocrinopathy, skin changes, papilloedema and biological abnormalities such as elevated vascular endothelial growth factor (VEGF), thrombocytosis or polycythaemia. We describe an observation of a patient with recurrent thrombosis with thrombocytosis that, after excluding a myeloproliferative neoplasm, proved to be due to POEMS syndrome. Read More

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http://dx.doi.org/10.1684/abc.2020.1534DOI Listing

Analytical validation of 13 biochemistry parameters (CEA, CA 19-9, amylase, lipase, sodium, potassium, chloride, creatinine, glucose, protein, albumin, LDH, triglycerides) in body fluids.

Ann Biol Clin (Paris) 2020 Feb;78(1):93-107

Service de biochimie et génétique moléculaire, CHU Clermont-Ferrand, Clermont-Ferrand, France.

The measurement performance of 13 biochemistry parameters (CEA, CA 19-9, amylase, lipase, sodium, potassium, chloride, creatinine, glucose, protein, albumin, LDH, triglycerides) was tested in a panel of biological fluids other than blood and urine (peritoneal, pleural, pancreatic fluids ... Read More

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http://dx.doi.org/10.1684/abc.2020.1524DOI Listing
February 2020

Examples of accreditation of serum and urinary proteins electrophoresis.

Ann Biol Clin (Paris) 2020 Feb;78(1):87-92

Hôpital Lapeyronie, Montpellier, France.

Serum proteins and urinary proteins electrophoresis are useful biological tests. They are often prescribed for the screening of monoclonal gammopathys and also during follow-up for treatment response. This test can be accredited according to standard NF ISO 15189 since laboratories use analysers and adapted reagents, but there are numerous protocols for the method validation. Read More

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http://dx.doi.org/10.1684/abc.2020.1527DOI Listing
February 2020

Mastering the analytical process of the Complete Blood Count: how and why?

Ann Biol Clin (Paris) 2020 Feb;78(1):79-86

Département de pharmacie, Faculté de médecine, Université de Constantine, Unité d'hémobiologie, Laboratoire central, Hôpital militaire régional universitaire HMRU, Constantine, Algérie.

This is a prospective study realized at the level of the hematology department and blood transfusion center of the University Hospital Center (CHU) of Dr Ben Badis of Constantine and spread out over a period of one year (from January 1st to December 31st). The work focused on the analytical processes mastery of the NFS needs a compulsory step concerning technical and organizational laboratory skills respecting the ISO 15189 laws going through a mastery of support processes (humain resourses, informatics, materials, documents, management) indispensable for the good function of analytic proceedings, a performance evaluation of the hematology analyzer Advia (2120 I and II and 560) and quality control management (intern, extern). The analytic performance evaluation of Advia gives reliable results reproductible and stable for use of the routine automatisation good inter-machine correlation and laboratory performance in terms of the quality extern evaluation with military hospital laboratory. Read More

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http://dx.doi.org/10.1684/abc.2020.1516DOI Listing
February 2020

Nosocomial infection control committee's role in a nosocomial infection at an East Algiers hospital.

Ann Biol Clin (Paris) 2020 Feb;78(1):74-78

Laboratoire central de biologie, EPH de Rouïba, Alger, Algérie, Faculté de médecine, Université d'Alger I, Alger, Algérie.

Nosocomial infections remain a serious public health problem with serious consequences. Hospital hygiene surveys are a basic tool in the surveillance and control of nosocomial infections. These surveys are also a tool for raising the awareness and information of the nursing staff. Read More

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http://dx.doi.org/10.1684/abc.2020.1517DOI Listing
February 2020

Lymphomas in immunocompromised patients.

Ann Biol Clin (Paris) 2020 Feb;78(1):7-16

Service de médecine interne, Centre hospitalier de Royan, Vaux-sur-mer, France, Groupement de coopération sanitaire de Saintonge, Laboratoire inter-hospitalier de biologie médicale (centres hospitaliers de Saint Jean d'Angély, Saintes, Jonzac et Royan), Saint Jean d'Angély, France.

Immunosuppression is a well known risk factor for the development of lymphoid pathologies. The classification of these neoplasias is becoming more precise and complex, some features being common to all immunocompromised patients, primarily the important influence of Epstein-Barr virus. Whatever the origin of the immunodepression, these lymphoid proliferations are very heterogeneous, constituting a wide range between polymorphic aspects and clearly lymphomatous morphologies indistinguishable from those observed in immunocompetent subjects. Read More

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http://dx.doi.org/10.1684/abc.2020.1521DOI Listing
February 2020

What to do in the event of a suspicion of analytical interference during an immunoassay?

Ann Biol Clin (Paris) 2020 Feb;78(1):70-73

Service de médecine nucléaire, CHU de Bordeaux, Bordeaux, France, Groupe de biologie spécialisée, Société française de médecine nucléaire, Paris, France.

Identifying analytical interference is a challenge for the medical biologist in providing advice to the prescriber. Indeed, these analytical interferences often have deleterious consequences on the care of patients. Understanding their mechanisms and mastering corrective procedures is essential to limit these management errors. Read More

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http://dx.doi.org/10.1684/abc.2020.1514DOI Listing
February 2020

Association of hemoglobinosis D-Punjab and β-thalassemia in a Moroccan family.

Ann Biol Clin (Paris) 2020 Feb;78(1):61-69

Service de biochimie-toxicologie, Hôpital militaire d'instruction Mohammed V, Rabat, Maroc, Faculté de médecine et de pharmacie, Université Mohammed V de Rabat, Maroc.

Hemoglobin D-Punjab is a common hemoglobin variant in India but very rare in Morocco. Often, its presence has minimal or no clinical impact. Its heterozygous association with β-thalassemia is exceptional. Read More

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http://dx.doi.org/10.1684/abc.2020.1523DOI Listing
February 2020

The wishes of the SFBC President.

Authors:
Vincent Sapin

Ann Biol Clin (Paris) 2020 Feb;78(1)

Président de la SFBC.

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http://dx.doi.org/10.1684/abc.2020.1526DOI Listing
February 2020

Criterium pencil mines as an alternative to platinum rods (Inoclic) in achievement of the antibiogram in agar medium for countries with limited resources?

Ann Biol Clin (Paris) 2020 Feb;78(1):54-60

CHU Montpellier - Hôpital Arnaud de Villeneuve, Département de bactériologie, Montpellier, France.

The realization of the antibiotic susceptibility test in agar is the routine bacteriological examination for the determination and monitoring of bacterial susceptibility to antibiotics. In this study, we report the comparative results between pencil leads for criterium, as an alternative to platinum rods in the realization of the antibiotic susceptibility test.

Methodology: Experimental study evaluating the comparability of the results between Criterium and Inoclic mines (by counting bacterial cells on agar after 5 successive dilutions of reason 10 from a bacterial suspension obtained after piercing through a colony; by measuring the inhibition diameters of 4 ATCC reference bacterial strains on an antibiogram in an agar medium) and evaluating the sterility of the criterium mines by culturing them on enriched broth (heart - brain type). Read More

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http://dx.doi.org/10.1684/abc.2020.1519DOI Listing
February 2020

Switching toward the use of recombinant factor VIII Fc fusion protein Study among 30 patients with severe hemophilia A.

Ann Biol Clin (Paris) 2020 Feb;78(1):35-46

Centre de ressource et de compétence, maladie hémorragique constitutionnelle, CHU Hautepierre, Strasbourg, France.

Only a few studies on real-world clinical use of recombinant factor VIII -fusionned with Fc (rFVIIIFc, efmoroctocog alpha) have been performed to date, with data on the annual bleeding rate (ABR), the prophylaxis regimen, and FVIII consumption. The aim of our study was to report the real-world clinical application of rFVIIIFc with additional elements, both biological and clinical. A prospective monocentric study has been conducted in the Haemophilia treatment center (HTC) of the Strasbourg university hospital among the severe haemophilia A patients. Read More

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http://dx.doi.org/10.1684/abc.2020.1520DOI Listing
February 2020

Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?

Ann Biol Clin (Paris) 2020 Feb;78(1):27-34

Service d'hématologie biologique, CHU Charles Nicolle, Rouen, France, Inserm U1096, CHU Charles Nicolle, Rouen, France.

Unfractionated heparin (UFH) is the main anticoagulante used in intensive care unit. The anticoagulant effect is monitored by activated partial thrombin time (aPTT) and anti-Xa activity (anti-Xa) measurement. However, delayed centrifugation induces platelet factor 4 (PF4) release and anti-Xa decrease. Read More

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http://dx.doi.org/10.1684/abc.2020.1525DOI Listing
February 2020

Electrophoresis of serum lipoproteins (lipoproteinogram) with the Hydragel Lipo + Lp(a)® (Sebia) kit: evaluation of Fat Red 7B staining.

Ann Biol Clin (Paris) 2020 Feb;78(1):17-26

Service de biochimie métabolique, AP-HP Sorbonne Université, Pitié-Salpêtrière-Charles Foix, Paris, France, Université de Paris, UTCBS, Inserm U1267, CNRS UMR 8258, Paris, France.

The lipoproteinogram (or lipidogram) consists in an electrophoretic separation of the main classes of serum lipoproteins. Separation was done in agarose gel using the Sebia Hydragel Lipo + Lp(a)® kit. A repeatability study (n=6) was conducted on 3 sera (1 normolipidemic, 1 hypertriglyceridemic and 1 with a high Lp(a) concentration). Read More

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http://dx.doi.org/10.1684/abc.2019.1510DOI Listing
February 2020

Lymphoid involvement of cerebrospinal fluid in Lyme disease.

Ann Biol Clin (Paris) 2020 Feb;78(1):108-110

Groupement hospitalier Lyon-Sud, Hospices civils de Lyon, Laboratoire d'hématologie biologique, France.

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http://dx.doi.org/10.1684/abc.2020.1515DOI Listing
February 2020

Contribution of the Uriselect4 and the CPS ID3 chromogenic media to the isolation and identification of urinary tract infections bacteria.

Ann Biol Clin (Paris) 2020 Feb;78(1):47-53

Laboratoire de biologie clinique, Institut National « Zouheir Kallel » de nutrition et de technologie alimentaire, Tunis, Tunisie, Faculté de pharmacie, Université de Monastir, Monastir, Tunisie.

Rapid and accurate identification of pathogens involved in urinary tract infections helps to guide antimicrobial therapy. Chromogenic agars provide presumptive identification directly from primary isolation media. They have been intended to make the bacterial isolation and identification process easier and faster. Read More

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http://dx.doi.org/10.1684/abc.2019.1512DOI Listing
February 2020

About the article "Recommendations for the application and the follow-up of quality controls in medical biology laboratories" Ann Biol Clin 2019 ; 77(5) : 577-97.

Authors:
Frédéric Sobas

Ann Biol Clin (Paris) 2020 02;78(1):113-114

Laboratoire d'hémostase, Centre de biologie Est, Bron, France.

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http://dx.doi.org/10.1684/abc.2019.1513DOI Listing
February 2020

Adequate prescription of medical biology exams: what perspective of it's valorization?

Ann Biol Clin (Paris) 2020 Feb;78(1):111-112

Hôpital André Mignot, Service de biologie, Le Chesnay, France.

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http://dx.doi.org/10.1684/abc.2019.1509DOI Listing
February 2020

Lu pour vous dans….

Authors:

Ann Biol Clin (Paris) 2019 Dec;77(6):718-720

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http://dx.doi.org/10.1684/abc.2019.1507DOI Listing
December 2019

Branch of Biologie Sans Frontières Ile-de-France area: activities and prospects.

Ann Biol Clin (Paris) 2019 Dec;77(6):697-699

Biologie Sans Frontières Île-de-France, France, Biologie Sans Frontières Lyon, France.

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http://dx.doi.org/10.1684/abc.2019.1485DOI Listing
December 2019

Biotin analytical interference on Siemens immunoanalysis on Dimension EXL®: impact on cardiac troponin I and total vitamin D (D+D) assays.

Ann Biol Clin (Paris) 2019 Dec;77(6):693-696

Laboratoire de biochimie hormonologie et génétique moléculaire, UMR 1179, Hôpital Ambroise Paré, Boulogne-Billancourt, France.

Several hyperthyroidism misdiagnoses cases have been recently described due to biotin intake. Biotin used in immuno-analysis assays which rely on biotin/streptavidin binding properties. In these assays, high plasmatic biotin levels can lead to major analytical interferences resulting in falsely higher (competition tests) or falsely reduced determinations (for sandwiches assays). Read More

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http://dx.doi.org/10.1684/abc.2019.1503DOI Listing
December 2019

Review of the sweat test indications in a Brussels' cystic fibrosis reference center.

Ann Biol Clin (Paris) 2019 Dec;77(6):687-692

Université libre de Bruxelles (ULB), Institut de mucoviscidose de l'ULB, Hôpital universitaire des enfants Reine Fabiola, Bruxelles, Belgique.

Sweat test is the gold standard of the diagnosis of cystic fibrosis (CF). The aim of our study was to identify the indications leading to perform a sweat test and those that led to the diagnosis of CF.

Methodology: We collected data of all sweat tests performed between 2008, 1th of March and 2015, 28th of February. Read More

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http://dx.doi.org/10.1684/abc.2019.1506DOI Listing
December 2019

Beware of the dog! Septic shock due to Capnocytophaga canimorsus revealed on peripheral blood smear.

Ann Biol Clin (Paris) 2019 Dec;77(6):685-686

Centre de biologie du Nivernais, Centre hospitalier de l'agglomération de Nevers, Nevers, France.

A blood smear examination led to the diagnosis of severe bacterial infection in a splenectomized patient. The knowledge of a relevant clinical information (recent dog bite) could have led to immediate presumptive identification of the causative agent, Capnocytophaga canimorsus. Read More

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http://dx.doi.org/10.1684/abc.2019.1508DOI Listing
December 2019

Accreditation strategy for rare somatic molecular abnormalities detected or quantified by polymerase chain reaction: GBMHM recommendations.

Ann Biol Clin (Paris) 2019 Dec;77(6):681-684

Laboratoire d'hématologie, Hôpital Nord, Centre hospitalier universitaire de Saint-Étienne, Saint-Étienne, France.

In 2020, accreditation of molecular tests according to ISO 15189 is a requirement for all French medical laboratories. For many years, the GBMHM group (French Group of Molecular Biologists in Hematology) supports this approach through organization of external quality evaluation campaigns, and by publishing recommendations that have allowed the accreditation of the most frequent molecular tests for most laboratories. However, some molecular abnormalities concerns very few patients (and sometimes a single patient), and therefore cannot be evaluated in the same way, because of the lack of external quality controls or inter-laboratory comparisons. Read More

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http://dx.doi.org/10.1684/abc.2019.1498DOI Listing
December 2019

Stability study and external quality assessment scheme implementation for complement components dosage on EDTA plasma.

Ann Biol Clin (Paris) 2019 Dec;77(6):669-680

CHU Lille, Institut d'immunologie, Lille, France, Université de Lille, U995-LIRIC-Lille Inflammation Research International Center, Lille, France.

Although the use of EDTA-containing collection tubes is known to stabilize the complement analytes and to make the results more reliable, no external quality assessment (EQA) scheme based on EDTA plasma samples is available to date in France. Consequently, a number of clinical laboratories currently participate to EQA program on samples whose matrix is different from their routine practice. The aim of this work was to offer a new external quality assessment scheme, as an inter-laboratory exchange (ILE). Read More

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http://dx.doi.org/10.1684/abc.2019.1501DOI Listing
December 2019

False-positive of blood culture instrument: leukocytosis, overfilled vials or defective position?

Ann Biol Clin (Paris) 2019 Dec;77(6):665-667

Service de biologie clinique, Hôpital Foch, Suresnes, France.

Continuous monitoring of the performances of blood culture instrument can be based on the indicators proposed by the QUAMIC. Of these, the analytic performance indicator evaluates the rate of false-positive vials. False-positives vials can be reported by the device in case of leukocytosis or when vials are overfilled. Read More

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http://dx.doi.org/10.1684/abc.2019.1500DOI Listing
December 2019

Macrophage activation syndrome revealing colon carcinoma About a case.

Ann Biol Clin (Paris) 2019 Dec;77(6):660-664

Laboratoire d'hématologie, Hôpital militaire Avicenne, Marrakech, Maroc.

Macrophage activation syndrome is a state of hyper-inflammation that results from increased secretion of proinflammatory cytokines, responsible of the inappropriate activation and proliferation of cells from the lymphohistiocyte lineage. It associates clinical signs, biological abnormalities and images of haemophagocytosis. It is a rare but serious attack, that can be "primary" or "secondary" to an infection, neoplasia, or autoimmune disease. Read More

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http://dx.doi.org/10.1684/abc.2019.1488DOI Listing
December 2019