4,705 results match your criteria Annales Pharmaceutiques Francaises[Journal]


[Optimization of the "pharmaceutical consultation" practice by pharmacists - Review, feedback and future proposals for development since the introduction of the initiative in 2013 focusing on the Calvados area.]

Ann Pharm Fr 2020 Jun 20. Epub 2020 Jun 20.

100D Rue Ciriel, 74500 Saint Paul en Chablais, France.

In 2012, a National Agreement of Pharmacists was initiated in France and then amended in 2013 to introduce the "Pharmaceutical consultation". These consultations must be conducted by the pharmacist with the patient in a confidential area in pharmacy or patient residence. The objective is to decrease the frequency of negative side effects of the medical treatments (Anti-vitamins K, Direct Oral Anticoagulants and inhaled corticoid) and to improve the correct use of medication therefore assure the safety of the patient. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.006DOI Listing

[Ethics and biomedical research during the COVID-19 epidemic: let's not confuse speed and precipitation!]

Ann Pharm Fr 2020 Jun 19. Epub 2020 Jun 19.

Service de Médecine Intensive et Réanimation, CH de Cannes, France; Comité d'éthique du CH de Cannes, France.

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http://dx.doi.org/10.1016/j.pharma.2020.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305705PMC

Pharmaceutical applications of silk sericin.

Ann Pharm Fr 2020 Jun 19. Epub 2020 Jun 19.

Department of Pharmaceutical Chemistry, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur, 425405, Maharashtra state, India. Electronic address:

Silk sericin is an applicable protein extracted from dried silk cocoons which are composed of a polar amino acid chain with hydroxyl, carboxyl, and amino functional groups. It anticipated that the functionality present in sericin provides excellent assets such as stability, release-modifying capacity, interaction with molecules, etc. It has various significant properties like biocompatibility, biodegradability, non-toxicity, hydrophilicity, etc. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.005DOI Listing

[Antimicrobial activity of Rosmarinus officinalis and Zingiber officinale extracts on the species of the genus Candida and on Streptococcus pneumonia.]

Authors:
Souad Akroum

Ann Pharm Fr 2020 Jun 18. Epub 2020 Jun 18.

Laboratoire de biologie moléculaire et cellulaire. Faculté des sciences de la nature et de la vie, Université Mohammed Seddik Benyahia, BP 98 rue Ouled Aissa, Jijel, Algérie. Electronic address:

Objective: Identifying plant extracts that could be used as new treatments for candidiasis and Streptococcus pneumoniae infections.

Methods: In this work, we tested the activity of the ethanolic and methanolic extracts of Rosmarinus officinalis and Zingiber officinale on Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei and Streptococcus pneumoniae. The antimicrobial activity was first tested in vitro, then in vivo on mice and rats. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.003DOI Listing

[Patient support in pharmaceutical practice: Update on formalized care plans].

Ann Pharm Fr 2020 Jun 18. Epub 2020 Jun 18.

Unité Territoriale d'Education du Patient, Groupe Hospitalier Paris Sud, 78 Rue du Général Leclerc, 94270 Le Kremlin-Bicêtre, France.

The evolution of patient management has led the pharmacist to change his posture and get closer to the patient. To better ensure these missions, several educational and support programs have emerged. "Advice", "consultations" and "pharmaceutical interviews", "shared medication report" or "therapeutic patient education", all these programs are intended " guarantee the best conditions for initiation, monitoring and compliance as well as evaluation of treatment ", taking into account the whishes and needs of patients. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.004DOI Listing

[Medical biostatistics with GMRC Shiny Stats - learning by doing].

Ann Pharm Fr 2020 Jun 18. Epub 2020 Jun 18.

Groupe Méthode en Recherche Clinique - Hôpitaux Universitaires de Strasbourg, 1 place de l'hôpital, 67000 Strasbourg, France. Electronic address:

Biostatistics are omnipresent in the scientific and medical literature and are an essential skill for any health student. We have developed a practical training tool - GMRC Shiny stats - an interactive application specifically dedicated to medical data statistical analysis. The application has been designed to provide an analysis workflow corresponding to the usual progression of an experienced statistician during data analysis. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.001DOI Listing

[BOMBAX COSTATUM EXTRACT ABROGATES PIROXICAM-MEDIATED HEPATIC AND GASTRIC TOXICITIES IN RATS].

Ann Pharm Fr 2020 Jun 18. Epub 2020 Jun 18.

Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Nile University of Nigeria, Abuja, Nigeria.

Objective: Concurrent administration of orthodox drugs and herbs is common in tropical Africa. This study investigates the effect of co-administration of piroxicam and Bombax costatum on hepatic and gastric toxicities and levels of oxidative stress markers.

Materials And Methods: Twenty male wistar rats were grouped into four. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.06.002DOI Listing

Risk evaluation of the use of Complementary and Alternatives Medicine in cancer.

Ann Pharm Fr 2020 May 30. Epub 2020 May 30.

Groupe Hospitalier Paris Saint-Joseph, Pneumology and Thoracic department, 185 rue Raymond Losserand, 75014 Paris, France. Electronic address:

Cancer patients use complementary and alternative medicine (CAM) to improve their well-being. Little is known about real risks.

Objective: To highlight 3 different types of axes: 1/cancer patients' perceptions concerning CAM; 2/misinformation/miscommunication about CAM; 3/ CAM toxicity (direct toxicity, CAM-anticancer drugs, CAM-cancer interactions). Read More

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http://dx.doi.org/10.1016/j.pharma.2020.05.001DOI Listing

Initiatives to reduce the inappropriate use of proton pump inhibitors in an outpatient primary care clinic.

Ann Pharm Fr 2020 May 30. Epub 2020 May 30.

Department of Internal Medicine, Upstate Medical University, Syracuse, NY, 13210, United States.

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http://dx.doi.org/10.1016/j.pharma.2020.05.002DOI Listing

On the dimorphism and the pressure-temperature state diagram of gestodene, a steroidal progestogen contraceptive.

Ann Pharm Fr 2020 Jul 29;78(4):303-309. Epub 2020 Mar 29.

Laboratoire SMS - EA 3233, Université de Rouen-Normandie, 76821 Mont-Saint-Aignan, France; Faculté de Pharmacie, Université de Paris, 4, avenue de l'observatoire, 75006 Paris, France. Electronic address:

The pressure-temperature phase diagram of the dimorphism of the contraceptive drug gestodene is constructed using the temperature and enthalpy of fusion of form I (469.5K, 107Jg), and those of the endothermic transition from form II to form I (311K, 8.52Jg). Read More

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http://dx.doi.org/10.1016/j.pharma.2020.03.002DOI Listing

[Discontinuation of Chromium-51 for clinical use: What are the possible alternatives for radiopharmacies and nuclear medicine departments?]

Ann Pharm Fr 2020 Jul 23;78(4):335-342. Epub 2020 Jan 23.

Centre Henri-Becquerel, 76038 Rouen cedex, France; QuantIF - LITIS [EA4108-FR CNRS 3638], IRIB, université de Rouen, Rouen, France. Electronic address:

Objectives: Last October, the nuclear medicine departments were informed of the closure of the chromium-51 production line for clinical use. This radionuclide has different diagnostic indications in nephrology and hematology. It was therefore essential to set up alternative exploration protocols to overcome this production stoppage. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.006DOI Listing

Complication risk factors related to central venous catheter in pediatric.

Ann Pharm Fr 2020 Jul 9;78(4):310-318. Epub 2020 Feb 9.

Pharmacie, centre hospitalier de Mayotte, rue de l'Hôpital, 97600 Mamoudzou, Mayotte.

Background: A prospective epidemiological study was carried out in the pediatric intensive care unit (ICU), at the Mayotte Hospital Center (MHC). The purpose of the study was to identify and to evaluate complications risk factors related to central venous catheterization. Improving side effects prevention and patients care was the second goal. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.02.001DOI Listing

[Case report of an infant hyperkalemia: Suggestion of a hospital procedure for the milk pretreatment with sodium polystyrene sulfonate resin].

Ann Pharm Fr 2020 Jul 3;78(4):287-293. Epub 2020 Apr 3.

Pôle pharmacie stérilisation, CHRU de Nancy, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France; APEMAC, université de Lorraine, 54000 Nancy, France.

Sodium polystyrene sulfonate (SPS) is used to reduce intestinal potassium absorption in hyperkalemia during conservative management of chronic renal failure in infants. Milk can be pretreated by SPS to reduce the risk of enteropathy associated with oral or rectal administration. We report the case of an infant for whom this pre-treatment has been implemented. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.02.005DOI Listing

Green HPTLC and Stability-Indicating RP-HPLC for the assay of Dextromethorphan Hydrobromide and Menthol in their Lozenges.

Ann Pharm Fr 2020 May 10. Epub 2020 May 10.

Pharos University Faculty of Pharmacy and Drug Manufacturing, Alexandria, Egypt.

Two chromatographic methods were developed for the assay of the FDA approved lozenges containing dextromethorphan hydrobromide (DXT) and menthol (MNT). The first was a green HPTLC method which uses a mobile phase of methanol-ammonia (10:0.1, v/v). Read More

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http://dx.doi.org/10.1016/j.pharma.2020.04.006DOI Listing

Vaccine distrust: Investigation of the views and attitudes of parents in regard to vaccination of their children.

Ann Pharm Fr 2020 Jul 2;78(4):294-302. Epub 2020 Apr 2.

Clinical pharmacy unit, Nantes university hospital, 1, place Alexis-Ricordeau, Nantes, France; Laboratory of clinical and experimental therapeutics of infections, Nantes university, 22, boulevard Benoni-Goullin, Nantes, France. Electronic address:

Background: In France, many parents have lost confidence in vaccinations, which has a direct impact on immunization coverage. Pharmacists, like other health professionals, often encounter parents exhibiting vaccine distrust.

Methods: Using a survey distributed in a school and in a number of volunteering pharmacies, the objective of this study was to gain a better understanding of the views and the attitude of parents in regard to vaccination of their children. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.03.003DOI Listing

[Cov19, seroprevalence studies and Individuals Protection Committees: aren't the technological and organizational challenges enough ?]

Authors:
C Huriet F Megerlin

Ann Pharm Fr 2020 07 28;78(4):285-286. Epub 2020 Apr 28.

Membre de l'Académie nationale de pharmacie, Paris, France; Centre d'études internationales et européennes EA 7307/CNRS FR 3241, université de Strasbourg, Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharma.2020.04.001DOI Listing

Screening of nanoemulsion components for asenapine maleate using validated RP-HPLC method.

Ann Pharm Fr 2020 May 6. Epub 2020 May 6.

School of Pharmacy, Faculty of Health and Medical Science, Taylor's University, Malaysia. Electronic address:

A novel, simple reversed-phase high-performance liquid chromatographic (RP-HPLC) analytical method was developed and validated for the quantitative determination of asenapine from various nanoemulsion components during pre-formulation screening. The developed method was validated according to ICH Q2 (R1) guidelines. The developed and validated method was precisely and accurately quantified asenapine in various oils, surfactants and co-surfactants. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.04.005DOI Listing

[Interchangeability and substitution of biosimilars].

Authors:
A Astier

Ann Pharm Fr 2020 Jul 7;78(4):277-284. Epub 2020 May 7.

Biotopic pharmaceuticals, 16, rue Gay-Lussac, 75005 Paris, France. Electronic address:

The rationality of the interchangeability of biosimilars is based on broad scientific evidence and numerous clinical experiences in real life which show no sign of reduced efficacy or different tolerance compared to the original molecule. The substitution of biosimilars (pharmaceutical act) remains widely contested in many countries, notably in France. However, it would make it possible to make very significant savings in a context of major acceleration in health spending. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.04.004DOI Listing

Validated Spectrophotometric Determination of Maduramicin Ammonium Using Three Charge Transfer Complexation Reactions.

Ann Pharm Fr 2020 May 6. Epub 2020 May 6.

Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Elmessalah, 21521 Alexandria, Egypt. Electronic address:

Direct spectrophotometric determination of Maduramicin ammonium (MAD) represents an analytical challenge since it is a weak UV-absorbing and lacking a strong chromophore. This work represents the first spectrophotometric determination of MAD as no direct spectrophotometric or colorimetric determination methods for MAD are available in the literature. The present study illustrates the development of three simple, rapid and inexpensive colorimetric methods for the routine quality control analysis of MAD based on the formation of colored charge transfer complexes with three electron acceptors namely p-chloranilic acid (p-CA), 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) and picric acid (PA). Read More

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http://dx.doi.org/10.1016/j.pharma.2020.04.002DOI Listing

[Letters to the article "Aluminium adjuvant exposure through vaccines in France in 2018"].

Authors:

Ann Pharm Fr 2020 05 30;78(3):273-275. Epub 2020 Mar 30.

4, avenue de l'Observatoire, France.

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http://dx.doi.org/10.1016/j.pharma.2020.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151301PMC

[Perspectives on the training of the pharmacist among pharmacists, academics and pharmacy students: A cross-sectional study].

Ann Pharm Fr 2020 May 9;78(3):242-251. Epub 2020 Feb 9.

Laboratoire de parasitologie, UFR de pharmacie, université de Reims-Champagne-Ardenne, 51, rue Cognacq-Jay, 51100 Reims, France.

Objectives: The evolution of community pharmacist education is guided by successive reforms. They aim to reduce the gap between academic education and community pharmacy practice but the perception regarding these reforms is poorly documented. The present study describes the cross-perceptions between community pharmacists, pharmacy students and academics teachers regarding the gap between academic education and community pharmacy practice, and, therefore, the essential knowledges and skills for the community pharmacy practice. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.02.003DOI Listing

Micellar high performance liquid chromatographic method for separation and validation of two anti-hepatitis C- virus drugs in pure form, human plasma and human urine.

Ann Pharm Fr 2020 May 9;78(3):217-229. Epub 2020 Feb 9.

Aga Health Insurance Hospital, Dakahlia. Electronic address:

Objectives: In the present study, an eco- friendly micellar liquid chromatographic technique was validated for separation and quantification of two drugs; namely ribavirin (RIV), and sofosbuvir (SBV) in pure form, pharmaceuticals containing them, human plasma and human urine. These drugs are administered co-administered for treatment of Hepatitis C virus (HCV) that causes hepatitis C in humans.

Material And Methods: These drugs were separated using Nucleosil 100-5 phenyl column. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.007DOI Listing

[Neonates exposure to parabens through medicines administered to inpatients].

Ann Pharm Fr 2020 Jul 23;78(4):343-350. Epub 2020 Jan 23.

Centre d'investigation clinique CIC Inserm 1402, Axe HEDEX (Health-Endocrine Disruptors-EXposome), 6, rue de la Milétrie, 86021 Poitiers, France; Service pharmacie, faculté de médecine et de pharmacie, université de Poitiers, centre hospitalier universitaire de Poitiers, 6, rue de la Milétrie, 86021 Poitiers, France.

Objectives: The objective of this study was to quantify parabens intake due to drug administration in neonates during hospitalization following their birth.

Method: A monocentric prospective study was performed into a neonatalogy unit to collect all drug prescriptions. An exhaustive list of parabens containing medicines commercialized in France was completed from Theriaque® database. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.005DOI Listing

[Service rendered's assessment of a pharmaceutical information center on patients care].

Ann Pharm Fr 2020 Jul 10;78(4):319-323. Epub 2020 Feb 10.

Centre de documentation et d'information pharmaceutique, pharmacie Centrale, hospices civils de Lyon, 57, rue Francisque-Darcieux, 69230 Saint-Genis Laval, France. Electronic address:

The Question-Answer (Q/R) service of Lyon's teaching hospital, offers reliable and updated information for healthcare professionals (HP). The impact of Q/R activity on patient outcome was measured by using a survey to assess user's satisfaction and impact on HP knowledge and/or patients cares. The compatibility of this tool with daily use had been assessed too. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.02.002DOI Listing

[Idiosyncratic drug-induced agranulocytosis: 7 year-analysis in a French university hospital].

Ann Pharm Fr 2020 May 10;78(3):230-241. Epub 2020 Feb 10.

Centre régional de pharmacovigilance, CHU de Grenoble-Alpes, 38000 Grenoble, France.

Introduction: Idiosyncratic drug-induced agranulocytosis is a rare but potentially serious haematological disorder. The pathophysiological mechanisms are complex and poorly understood. We aimed at investigating agranulocytosis drug related causes from the myelograms with "myeloid maturation arrest" performed in our university hospital over the last seven years. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.02.004DOI Listing

Monolithic and core-shell particles stationary phase morphologies in protein analysis; peptide mapping of erythropoietin hormone and determination of carbetocin.

Ann Pharm Fr 2020 May 10;78(3):206-216. Epub 2020 Feb 10.

Pharmaceutical analytical chemistry department, faculty of pharmacy, Zagazig university, Zagazig, Egypt.

Chromatographic application of two recent HPLC stationary phases for protein analysis was demonstrated. These two stationary phases are namely monolithic rods and core-shell particles. Monolithic rods have higher permeability and larger porous structure allowing faster elution, while smaller core-shell particles have narrower particle size distribution and better packing allowing larger number of resolved peptides. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.008DOI Listing

[Methodology to develop a virtual reality training for good practices in the preparation of anti-cancer drugs].

Ann Pharm Fr 2020 Jul 23;78(4):324-334. Epub 2020 Jan 23.

Association pour le digital et l'information en pharmacie (ADIPh); Service pharmacie, centre hospitalier intercommunal Alençon-Mamers, France. Electronic address:

Objective: Describe the process for designing and creating SimUPAC 360°, a virtual reality training in anti-cancer drug production units.

Methods: A multi-centre (a University Hospital, a General Hospital and a Cancer Control Centre), inter-professional (pharmacists, hospital pharmacy technicians and health executives) working group has been set up. It was based on videoconferencing and online document sharing. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.12.006DOI Listing

Formulation and clinical evaluation of the standardized Litchi chinensis extract for skin hyperpigmentation and aging treatments.

Ann Pharm Fr 2020 Mar 23;78(2):142-149. Epub 2020 Jan 23.

School of Cosmetic Science, Mae-Fah-Luang University, 57100 Chiang-Rai, Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae-Fah-Luang University, 57100 Chiang-Rai, Thailand.

Introduction: The standardized litchi extract had been revealed on phytochemical actives, in vitro and cellular activities against aging and darkening of skin. However, a formulation containing the extract has never been developed as per clinical evaluated.

Materials And Methods: The litchi serum was developed, safety and efficacy were clinically evaluated in human volunteers. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.004DOI Listing

[Aluminium adjuvant exposure through vaccines in France in 2018].

Ann Pharm Fr 2020 Mar 17;78(2):111-128. Epub 2020 Jan 17.

Inserm U955 E10, centre expert de pathologie neuromusculaire, « Biologie du système neuromusculaire », hôpital Henri-Mondor, faculté de médecine, université Paris-Est-Créteil, 94010 Créteil, France; École nationale vétérinaire d'Alfort, Maisons-Alfort, France. Electronic address:

Objectives: Aluminum-containing vaccine adjuvants stimulate an adequate immune response to vaccination. The safety and rapid elimination of these molecules, a guarantee of their safe use for several decades, have been challenged by a growing number of studies over the last 20 years. Evaluation of exposure to aluminum adjuvants of an individual is thus essential. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.002DOI Listing

Fourier convolution versus derivative spectrophotometry: Application to the analysis of two binary mixtures containing tamsulosin hydrochloride as a minor component.

Ann Pharm Fr 2020 Mar 23;78(2):129-141. Epub 2020 Jan 23.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt.

Simple and rapid spectrophotometric methods are described for determination of two mixtures of tamsulosin (TM), as minor component, with either solifenacin (SL) or tolterodine (TL). The proposed methods involve treatment of the absorbance ratio spectra or zero order spectra by derivative or discrete Fourier function. TM and TL mixture could not be resolved by manipulation of their zero order spectra due to the strong overlap between both spectra and only derivative or Fourier function coefficients of ratio spectra could resolve their spectra. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.003DOI Listing

Reassessment of inappropriate prescriptions of proton pump inhibitors in elderly in-patients: It's time to take action.

Ann Pharm Fr 2020 Mar 17;78(2):150-157. Epub 2020 Jan 17.

Department of pharmacy, Tours University Hospital, 37000 Tours, France; Inserm, UMR 1253, iBrain, Tours University, 37000 Tours, France. Electronic address:

Objectives: To determine the impact of awareness sessions, proposed by the pharmaceutical team to the hospital physicians, on the reassessment of off-label non-hospital proton pump inhibitor prescriptions dedicated to hospitalized patients in the internal medicine department of a university hospital.

Methods: We conducted a retrospective and comparative cohort study of in-patients aged 65 years old and older with a prescription including a proton pump inhibitor. Patients who were admitted before the implementation of the awareness sessions were enrolled in the control group; others were enrolled in the awareness experimental group. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.001DOI Listing

Caregiver in Alzheimer's disease, pharmacist, and pharmacy technician attitudes and knowledge about caregiver burden screening in community pharmacies.

Ann Pharm Fr 2020 May 16;78(3):199-205. Epub 2019 Dec 16.

Service pharmaceutique, hôpital des Charpennes, hospices civils de Lyon, 69100 Lyon, France; Université Lyon 1, 69000 Lyon, France; Équipe dynamique cérébrale et cognition, Inserm U1028, CNRS UMR5292, centre de recherche en neuroscience de Lyon, 69000 Lyon, France.

Objectives: To explore caregiver, pharmacist and pharmacy technician attitudes toward burden screening in community pharmacies and assess caregiver burden in community pharmacies.

Methods: Descriptive cross-sectional study conducted in 10 community pharmacies in France. Pharmacists, pharmacy technicians and caregivers of patients with Alzheimer's disease were included in this study. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.12.002DOI Listing

[Wholesale distribution and delivery of plant-based medicinal products through the pharmaceutical system of Burkina Faso].

Ann Pharm Fr 2020 Mar 16;78(2):179-188. Epub 2019 Dec 16.

Laboratoire du développement du médicament, école doctorale sciences et santé (ED2S), université Joseph Ki-Zerbo, 03 BP 7021, Ouagadougou 03, Burkina Faso. Electronic address:

Objective: In order to improve the contribution of medicines from traditional pharmacopoeia to health care, African countries like Burkina Faso have adopted for several years, policies and regulations organizing their distribution. This study aims to analyze the situation of the wholesale and retail sale of herbal medicines imported by the official pharmaceutical facilities.

Method: This is a retrospective study involving all 18 drug wholesalers and 115 pharmacies in the city of Ouagadougou (Burkina Faso). Read More

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http://dx.doi.org/10.1016/j.pharma.2019.12.003DOI Listing

[Community pharmacists' and pharmacy technicians' attitudes and beliefs about depression in elderly].

Ann Pharm Fr 2020 Mar 16;78(2):167-178. Epub 2019 Dec 16.

Université de Lyon 1, 69000 Lyon, France; Service pharmaceutique, institut du vieillissement, hôpital des Charpennes, hospices civils de Lyon, 69100 Lyon, France; EA-7425 HESPER, Health Services and Performance Research, université de Lyon, 69003 Lyon, France. Electronic address:

Objectives: To analyze attitudes and beliefs of community pharmacists and pharmacy technicians about depression and treatment in older patients.

Methods: A qualitative study was conducted with community pharmacists and pharmacy technicians. The first step of the study was to develop an interview guide to conduct semi-directive interviews. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.11.001DOI Listing

[Reevaluating the shelf life of sterilized packaged items via a risk-analysis study].

Ann Pharm Fr 2020 May 13;78(3):264-272. Epub 2019 Dec 13.

Unité de stérilisation, service pharmacie, centre hospitalier de Valence, 179, boulevard du Maréchal Juin, 26953 Valence cedex 9, France.

In the hospital, all the reprocessed reusable medical devices (RMD) are conditioned with a sterile barrier system and a protection package and they expire after three months. The objective of this study is to reevaluate this shelf life via a risk-analysis study focusing on the steps whose malfunction can fail RMD sterility. The first step is analysing current conditions of packaging, transportation and storage of RMD. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.12.001DOI Listing

Improving safety of preparation and administration of medicines and enteral nutrition in a neonatal care unit: Global risk analysis.

Ann Pharm Fr 2020 Mar 13;78(2):158-166. Epub 2019 Dec 13.

Pharmacy Department, Hôpital Foch, Suresnes, France 40, rue Worth, 92150 Suresnes, France. Electronic address:

Objective: To date, few adapted pharmaceutical forms are available for infants leading to multiple steps of preparation and medicines dilution before administration. The main purpose of this study was to assess the risks on the steps of preparation and administration of medicines in a neonatal care unit and to propose corrective actions to ensure the medicines safety.

Methods: A global risk analysis was performed, conducted by a multidisciplinary working group of 9 experts, that is 9 meetings. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.12.005DOI Listing

[Reorganization of clinical trial activity in a hospital pharmacy: Contribution of Lean management].

Ann Pharm Fr 2020 Jan 1;78(1):87-95. Epub 2019 Nov 1.

Service pharmacie, hôpital de la Croix-Rousse, Hospices Civils de Lyon, 103, grande rue de la Croix-Rousse, 69004 Lyon, France. Electronic address:

Objectives: Hospital pharmacists are involved in clinical trials for the management of experimental drugs. In our hospital, the pharmacy is in charge of approximately 120 clinical trials and this activity is sub-divided between three sectors. The fragmentation of this activity generates difficulties in terms of heterogeneity of practices, redundancy of activities, and difficulties of communication with stakeholders outside the pharmacy due to the multiplicity of pharmaceutical interlocutors. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.005DOI Listing
January 2020

[Feedback on clinical oncology pharmacy].

Ann Pharm Fr 2020 Jan 31;78(1):70-75. Epub 2019 Oct 31.

Service Pharmacie, Hôpital Timone, AP-HM, Marseille; Aix Marseille Université, Laboratoire de Pharmacie Clinique, Marseille.

The rising of oral anticancer therapies let more and more patients to be cared at home and improve their quality of life. However the toxicities of these drugs and the distance with health professionals imply that the patient needs to be more autonomous with respect to his treatment. Patients through therapeutic education programs allows them to manage side effects, to be more observant and then to subsequently benefit from the treatment. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.09.002DOI Listing
January 2020

[Health technology assessment of innovative medical devices: Timing and decision at national and local level].

Ann Pharm Fr 2020 Mar 2;78(2):189-197. Epub 2019 Nov 2.

Service pharmacie, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75015 Paris, France; EA7358 GRADES, université Paris-Sud, université Paris-Saclay, 5, rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France. Electronic address:

Introduction: The Medical Device Committee (CODIMS) evaluates all innovative medical devices (MD) before their introduction in the hospitals of the Assistance publique-hôpitaux de Paris (AP-HP). At the national level, the Medical Device and Health Technology Evaluation Committee (CNEDiMTS) provides recommendation for MD with respects to reimbursement by the National Health Insurance Fund. The aim of this study is to compare the recommendations of both committees and to analyze their timing on a six-year period. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.002DOI Listing

Validated RP-HPLC method for quantification of doxazosin in human plasma: Application in a bioequivalence study.

Authors:
N O Mansour

Ann Pharm Fr 2020 Jan 2;78(1):42-48. Epub 2019 Nov 2.

Pharmaceutical service center, faculty of Pharmacy, Tanta university, 8310 Tanta, Egypt. Electronic address:

Objectives: The aim of the present study was to validate a simple, sensitive, HPLC method of analysis of doxazosin in human plasma with fluorescence detection.

Methods: The validated method employed one-step direct protein precipitation with acetonitrile. Chromatographic separation was attained using a reverse-phase 250mm×4. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.003DOI Listing
January 2020

Evidence of variations of endogenous halogenated volatile organic compounds in alveolar breath after mental exercise-induced oxidative stress.

Ann Pharm Fr 2020 Jan 5;78(1):34-41. Epub 2019 Nov 5.

Académie des sciences, 23, quai Conti, 75006, Paris, France. Electronic address:

Background: The effect of oxygen on markers of oxidative stress has not been totally elucidated because previous studies have yielded conflicting results.

Methods: A method for the collection and gas chromatography-mass spectrometry of the halogenated volatile organic compounds in human alveolar breath is described. A transportable apparatus sampled specifically alveolar breath; the volatile organic compounds were captured in a thermal desorption tube, Carbotrap 200®. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.004DOI Listing
January 2020

[Is the medication reconciliation achievable and relevant in Psychiatry?: Feedback on the implementation of medication reconciliation on hospital admission].

Ann Pharm Fr 2020 May 5;78(3):252-263. Epub 2019 Nov 5.

Service pharmacie hôpital Albert-Chenevier, hôpitaux universitaires Henri-Mondor AP-HP, 40, rue de Mesly, 94000 Créteil, France. Electronic address:

Objective: The health care pathway of patients suffering from mental disorders is complex and includes a risk of interruption of treatment. We implemented medication reconciliation at patients' admission to mental health care service in February 2017. The aim of this study was to achieve a feedback experience answering our questions about the feasibility and relevance of this process. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.007DOI Listing

Evaluation of the reliability of human teeth matrix used as a biomarker for fluoride environmental pollution.

Ann Pharm Fr 2020 Jan 1;78(1):21-33. Epub 2019 Nov 1.

Toxicology Laboratory and Toxicology-Environment Research Laboratory LR12SP07, El Manar University, Tunis, Tunisia.

Environmental contamination by heavy metals has been a matter of great concern in many countries for several decades. Human exposure to such elements may cause adverse health effects and young children are particularly at risk. Many matrixes have been used for determination of metal exposure levels. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.006DOI Listing
January 2020

[What do we expect from Radiopharmacy software?]

Ann Pharm Fr 2020 Jan 2;78(1):76-86. Epub 2019 Nov 2.

Radiopharmacie, hôpital Privé d'Antony, 1, rue Velpeau, 92160 Antony, France.

The Radiopharmaceutical Health Products circuit or RHP (radiopharmaceutical drugs, radiopharmaceutical preparation and radioactive implantable medical devices) is a complex process that nowadays requires computerization. This circuit must be in accordance with both the legislation on medicinal products and the legislation on artificial radioelements. It is acknowledged that computerization of the circuit; possibly different within each organization, provides assistance to stakeholders: pharmaceutical analysis of prescription, pharmaceutical preparation and preparation of doses to be dispensed and waste management for example. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.10.001DOI Listing
January 2020

[Predatory journals, a threat not to be neglected].

Authors:
Y Touitou

Ann Pharm Fr 2019 11 27;77(6):443-445. Epub 2019 Sep 27.

Unité de chronobiologie, Fondation A. -de Rothschild, 25, rue Manin, 75019 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00034509193015
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http://dx.doi.org/10.1016/j.pharma.2019.08.004DOI Listing
November 2019
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Pharmaceutical applications of electrospinning.

Ann Pharm Fr 2020 Jan 26;78(1):1-11. Epub 2019 Sep 26.

Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, 127 SOC. NO. 1. R. K. Nagar, 416013 Kolhapur, India.

Development of tailor-made pharmaceutical nanofibers has gained vital prominence due to ease of fabrication and versatility of electrospinning (ES). ES is one of the flexible and, wonderful strategies for the fabrication of nanofibers. ES unit comprises a supplier of high voltage current, a syringe (pump), spinneret and a metal plate collector. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00034509183014
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http://dx.doi.org/10.1016/j.pharma.2019.07.002DOI Listing
January 2020
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[The radiolabeled blood cell: Finding a legal qualification].

Ann Pharm Fr 2020 Jan 26;78(1):49-57. Epub 2019 Sep 26.

Laboratoire parcours de santé systémique (P2S), université Joseph-Fourrier, 69372 Grenoble, France.

Radiolabelling of blood cells is a technique commonly used as a diagnostic tool in nuclear medicine; it has never been legally defined. This lack of legal status is a factor of uncertainty for both patients and health care professionals. The aim of this work was to identify what could be the legal nature of the radiolabelled blood cells by comparing their constitutive elements to the various existing legal categories applicable, according to the law applicable to living organisms as well as the regulations for other health products. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.09.001DOI Listing
January 2020

[Prospective risk analysis in a retrocession unit: Focus on drug dispensation process].

Ann Pharm Fr 2020 Jan 26;78(1):12-20. Epub 2019 Sep 26.

Pharmacie hôpital Edouard-Herriot, hospices civils de Lyon, 5, place d'Arsonval, 69003 Lyon, France; Université Claude-Bernard Lyon 1, 6, avenue Rockefeller, 69008 Lyon, France; EA 4129 parcours santé systémique, faculté de médecine Laënnec, 7-11, rue Guillaume-Paradin, 69372 Lyon cedex 08, France.

Objectives: Failure mode effect analysis (FMEA) improves safety in the drug life cycle. As the drug dispensation by hospital's pharmacy can be at risk, the FMEA tool has been used to evaluate and enhance the process.

Methods: After detailing the process, a first FMEA has been run in 2015. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.06.006DOI Listing
January 2020

[Factors associated with medication non-adherence in patients with type 2 diabetes mellitus: The first Algerian survey].

Ann Pharm Fr 2019 Nov 26;77(6):506-515. Epub 2019 Sep 26.

Département de médecine, faculté de médecine, université Djilali Liabès de Sidi Bel Abbès, 22000, Algérie.

Background: Non-adherence in patients with type 2 diabetes is a frequent phenomenon with important impact in terms of management of this disease. The aim of this study was to assess the level of medication adherence and to identify the factors associated with non-adherence in type 2 diabetic patients.

Methods: A cross-sectional study was conducted in type 2 diabetic patients at the endocrinology and diabetology department of University Medical Center of Sidi Bel Abbes (Algeria) in 2017. Read More

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http://dx.doi.org/10.1016/j.pharma.2019.08.003DOI Listing
November 2019
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