30,520 results match your criteria Ann. Surg.[Journal]


Conversion of Adjustable Gastric Banding to Stapling Bariatric Procedures: Single- or Two-stage Approach.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Department of Surgery, Stony Brook University, Stony Brook, NY.

Objective: The aim of this study was to compare the safety of single- versus two-stage conversion of adjustable gastric band (AGB) to gastric bypass (RYGB) or sleeve gastrectomy (SG).

Summary Background Data: AGB patients often present for conversion to RYGB or SG. The impact of single- or two-stage approach of such conversion remains unclear. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003332DOI Listing

Bariatric Surgery is Associated With Reduced Risk of Breast Cancer in Both Premenopausal and Postmenopausal Women.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Division of General Internal Medicine and Center for Clinical Effectiveness, University of Cincinnati, Cincinnati, OH.

MINI: We examined risk of breast cancer among 17,998 women who had bariatric surgery and 53,889 women matched on body mass index with no surgery. We found bariatric surgery was associated with a reduced risk of both premenopausal [hazard ratio (HR) = 0.72, 95% confidence interval (CI), 0. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003331DOI Listing
April 2019
2 Reads

Tapping Into Underutilized Healthcare Data in Clinical Research.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.

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http://dx.doi.org/10.1097/SLA.0000000000003329DOI Listing
April 2019
1 Read

A Call to Action for Male Surgeons in the Wake of the #MeToo Movement: Mentor Female Surgeons.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Hansjörg Wyss Department of Plastic Surgery, New York University School of Medicine, New York, NY.

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http://dx.doi.org/10.1097/SLA.0000000000003328DOI Listing

The Millennials are Here and They Expect More From Their Surgical Educators!

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.

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http://dx.doi.org/10.1097/SLA.0000000000003326DOI Listing
April 2019
1 Read

Adverse Outcomes After Bile Spillage in Incidental Gallbladder Cancers: A Population-based Study.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Department of Surgery, University of Calgary, Calgary, Alberta, Canada.

Objective: To determine the effect of bile spillage during cholecystectomy on oncological outcomes in incidental gallbladder cancers.

Background: Gallbladder cancer (GBC) is rare, but lethal. Achieving complete resection offers the best chance of survival. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003325DOI Listing

Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

MINI: Hemorrhage is the primary cause of preventable trauma death. Secondary analyses of scene patients from the PAMPer trial demonstrated that prehospital packed red blood cell and plasma had the greatest reduction in 30-day mortality compared with crystalloid-only resuscitation. Patients with hemorrhagic shock should receive prehospital blood products when available, preferably packed red blood cell and plasma. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003324DOI Listing

Response: Comment on "Guideline Assessment Project: Filling the GAP in Surgical Guidelines: Quality Improvement Initiative by an International Working Group".

Ann Surg 2019 Apr 13. Epub 2019 Apr 13.

European Association for Endoscopic Surgery Consensus and Guideline Subcommittee, Eindhoven, Netherlands Department of Surgery, European University Cyprus, Nicosia, Cyprus Department of Vascular and Endovascular Surgery, The Royal Oldham Hospital, Pennine Acute Hospitals NHS Trust, Manchester, UK Division of Cardiovascular Sciences, School of Medical Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1097/SLA.0000000000003319DOI Listing
April 2019
1 Read

Extracorporeal Perfusion for Extended Ischemia Time after Major Limb Amputation.

Authors:
Kyle R Eberlin

Ann Surg 2019 Apr 10. Epub 2019 Apr 10.

Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/SLA.0000000000003315DOI Listing

The Bigger the Better: Hepatic Vein Anastomosis for Small Liver Grafts.

Ann Surg 2019 May;269(5):e64

Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/SLA.0000000000003213DOI Listing

Association 'Between Gabapentinoids on the Day of Colorectal Surgery and Adverse Postoperative Respiratory Outcomes.

Ann Surg 2019 Apr 9. Epub 2019 Apr 9.

Patient Safety Center of Inquiry, Durham VA Medical Center, Durham, NC.

Objective: The aim of this study was to determine the association between gabapentinoids on the day of surgery and adverse postoperative outcomes in patients undergoing colorectal surgery in the United States.

Background: Gabapentinoids, gabapentin and pregabalin, are recommended in multimodal analgesia protocols for acute postoperative pain management after colorectal surgery. However, current literature focuses on the efficacy in reducing opioid consumption, but provides limited information about adverse risks. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003317DOI Listing
April 2019
1 Read

Changing the Paradigm of Craniofacial Reconstruction: A Prospective Clinical Trial of Autologous Fat Transfer for Craniofacial Deformities.

Ann Surg 2019 Apr 9. Epub 2019 Apr 9.

Department of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

Objective: This study aimed to prospectively assess outcomes for surgical autologous fat transfer (AFT) applied for traumatic and postsurgical craniofacial deformities. The minimally invasive nature of AFT has potential for reduced risk and superior outcomes compared with current reconstructive options.

Background: Craniofacial deformities have functional and psychosocial sequelae and can profoundly affect quality of life. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003318DOI Listing

Quality of Reporting on Guideline, Protocol, or Algorithm Implementation in Adult Trauma Centers: A Systematic Review.

Ann Surg 2019 Apr 9. Epub 2019 Apr 9.

Tory Trauma Research Program, Sunnybrook Research Institute, Toronto, ON, Canada.

Objective: To appraise the quality of reporting on guideline, protocol, and algorithm implementations in adult trauma settings according to the Revised Standards for Quality Improvement Reporting Excellence (SQUIRE 2.0).

Background: At present we do not know if published reports of guideline implementations in trauma settings are of sufficient quality to facilitate replication by other centers wishing to implement the same or similar guidelines. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003313DOI Listing

The Cost of Postoperative Complications and Economic Validation of the Comprehensive Complication Index: Prospective Study.

Ann Surg 2019 Apr 9. Epub 2019 Apr 9.

Department of General and Digestive Surgery, Hospital Universitario de Guadalajara, Spain.

Objective: To validate the Comprehensive Complication Index (CCI) via an assessment of its relation to postoperative costs.

Background: The CCI summarizes all the postoperative complications graded by the Clavien-Dindo classification (CDC) on a numerical scale. Its relation to hospital costs has not been validated to date. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003308DOI Listing

Response to Comment on "Risk of Posttransplant Hepatocellular Carcinoma Recurrence is Higher in Recipients of Livers From Male Than Female Living Donors".

Ann Surg 2019 May;269(5):e71

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Statistics and Data Center, Samsung Medical Center, Seoul, Korea Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1097/SLA.0000000000002881DOI Listing

Comment on "Risk of Posttransplant Hepatocellular Carcinoma Recurrence is Higher in Recipients of Livers From Male Than Female Living Donors".

Authors:
Wei Zhang Li Jiang

Ann Surg 2019 May;269(5):e71

Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.

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http://dx.doi.org/10.1097/SLA.0000000000002875DOI Listing

Response to Comment on "Mucus Microbiome of Anastomotic Tissue During Surgery Has Predictive Value for Colorectal Anastomotic Leakage".

Ann Surg 2019 May;269(5):e69-e70

Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/SLA.0000000000002857DOI Listing

Comment on "Is It Time to Reconsider Postoperative Epidural Analgesia in Patients Undergoing Elective Ventral Hernia Repair?"

Ann Surg 2019 May;269(5):e67

Digestive Disease Center, Bispebjerg University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1097/SLA.0000000000002906DOI Listing

Response to the comment on "Misinterpretation of Results With P > 0.05 May Harm Quality and Patient Safety".

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA Biostatistics Center, Massachusetts General Hospital Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/SLA.0000000000003314DOI Listing

County-level Variation in Use of Surgery and Cancer-specific Survival for Stage I-II Pancreatic Adenocarcinoma.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Surgery, University of Utah, Salt Lake City, UT.

Objective: The aim of the study was to describe county-level variation in use of surgery for stage I-II pancreatic ductal adenocarcinoma (PDAC) and the association between county surgery rates and cancer-specific survival (CSS).

Background: The degree of small geographic area variation in use of surgery for stage I-II PDAC and the association between area surgery rates and CSS remain incompletely defined.

Methods: This is a retrospective cohort study of patients aged 18 to 80 years in the 2007 to 2015 Surveillance, Epidemiology, and End Results database with stage I-II PDAC without contraindications to surgery or refusal. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003236DOI Listing

Should Zero Harm Be Our Goal?

Authors:
Thomas A Aloia

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

MINI: Should Zero Harm Be Our Goal in Surgery? While the answer to this question may seem obvious, there are downsides to this strategy. The purpose of this Surgical Perspectives is to explore the conflicts associated with "Aiming at Zero," and to propose an alternative paradigm. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003316DOI Listing

Endovascular Treatment of Post Type A Chronic Aortic Arch Dissection With a Branched Endograft: Early Results From a Retrospective International Multicenter Study.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

German Aortic Center, Department of Vascular Medicine, University Heart Center Hamburg, Hamburg, Germany.

MINI: The objective of this study was to evaluate the outcome of endovascular repair of chronic aortic arch dissecting aneurysms with a custom-made branched endograft during follow-up after acute type A aortic dissection open repair. Unmatched outcomes are reported in a population at high risk for a redo sternotomy.

Objective: The objective of this study was to evaluate the outcome of endovascular aortic arch repair for chronic dissection with a custom-made branched endograft. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003310DOI Listing
April 2019
1 Read

Laparoscopic Versus Open Pancreaticoduodenectomy: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany.

MINI: This systematic review and meta-analysis of randomized controlled trials compared laparoscopic to open pancreaticoduodenectomy for perioperative outcomes. No significant differences between the approaches except for lower blood loss and a longer operative time in the laparoscopic group were found. One trial was stopped for patient safety reasons in the laparoscopic group. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003309DOI Listing

Fluorescent and Iodized Emulsion for Preoperative Localization of Pulmonary Nodules.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Biomedical Science, College of Medicine, Korea University, Seoul, Korea.

MINI: Recent developments in near-infrared fluorescent imaging have revealed the usefulness of indocyanine green (ICG) for preoperative pulmonary nodule localization. However, it is difficult to determine the resection margins of deep-seated nodules using this technique, given the limited depth penetration and diffusion of ICG through the lung tissue without pooling around the lesion. The optimal fluorescent iodized emulsion, a mixture of ICG solution and Lipiodol (ethiodized oil), can overcome these limitations and may allow the accurate localization and resection of pulmonary nodules. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003300DOI Listing
April 2019
1 Read

Utilizing Machine Learning Methods for Preoperative Prediction of Postsurgical Mortality and Intensive Care Unit Admission.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Department of Anaesthesiology, Singapore General Hospital, Singapore.

MINI: We compared the performance of machine learning models against the traditionally derived Combined Assessment of Risk Encountered in Surgery (CARES) model and the American Society of Anaesthesiologists-Physical Status (ASA-PS) in the prediction of 30-day postsurgical mortality and need for intensive care unit (ICU) stay >24 hours. Machine learning can be used to improve surgical risk prediction compared to traditional risk calculators. AUPRC should be used to evaluate model predictive performance instead of AUROC when the dataset is imbalanced. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003297DOI Listing
April 2019
1 Read
8.327 Impact Factor

Definition of the Rectum: An International, Expert-based Delphi Consensus.

Ann Surg 2019 Apr 8. Epub 2019 Apr 8.

Royal Marsden NHS Foundation Trust, London, UK.

MINI: A radiological, anatomic distinction between the rectum and sigmoid colon was agreed by consensus of international experts in rectal cancer using the Delphi Technique. Use of this landmark, "the sigmoid take-off," may harmonize efforts in research and clinical practice to improve patient outcomes.

Background: The wide global variation in the definition of the rectum has led to significant inconsistencies in trial recruitment, clinical management, and outcomes. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003251DOI Listing

Patient Behaviors and Characteristics Related to Weight Regain After Roux-en-Y Gastric Bypass: A Multicenter Prospective Cohort Study.

Ann Surg 2019 Apr 4. Epub 2019 Apr 4.

Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

MINI: Our study identified several behaviors (eg, more sedentary time, eating fast food, binge eating, eating continuously, not weighing oneself regularly) and characteristics (eg, younger age, depressive symptoms) independently associated with greater weight regain after Roux-en-Y gastric bypass, which inform patient care to improve long-term weight loss maintenance.

Objective: To identify patient behaviors and characteristics related to weight regain after Roux-en-Y gastric bypass surgery (RYGB).

Background: There is considerable variation in the magnitude of weight regain after RYGB, highlighting the importance of patient-level factors. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003281DOI Listing
April 2019
10 Reads

Factors Predicting Response, Perioperative Outcomes, and Survival Following Total Neoadjuvant Therapy for Borderline/Locally Advanced Pancreatic Cancer.

Ann Surg 2019 Apr 5. Epub 2019 Apr 5.

Division of Medical Oncology.

MINI: Total neoadjuvant therapy, or systemic induction chemotherapy followed by chemoradiation, is an optimal preoperative sequencing strategy for patients with borderline resectable or locally advanced pancreatic adenocarcinoma. This strategy allows high rate of negative margins despite low frequency of radiologic downstaging with survival dependent on chemotherapy duration and response factors that are potentially modifiable by alteration in initial systemic therapy decisions.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003284DOI Listing
April 2019
1 Read

A National Analysis of Short-term Outcomes and Long-term Survival Following Thoracoscopic Versus Open Lobectomy for Clinical Stage II Non-Small-Cell Lung Cancer.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Department of Cardiothoracic Surgery, Stanford University Medical Center, Stanford, CA.

MINI: In this national analysis, thoracoscopic lobectomy was associated with shorter hospital stay and no significant difference in long-term survival when compared to open lobectomy for cT1-2N1M0 non-small-cell lung cancer (NSCLC). These results suggest that thoracoscopic techniques are feasible in the treatment of stage II (cN1) NSCLC.

Objective: To compare outcomes after open versus thoracoscopic (VATS) lobectomy for clinical stage II (cN1) non-small-cell lung cancer (NSCLC). Read More

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http://dx.doi.org/10.1097/SLA.0000000000003231DOI Listing
March 2019
2 Reads

Procedure-specific Training for Robot-assisted Distal Pancreatectomy.

Ann Surg 2019 Mar 28. Epub 2019 Mar 28.

Beth Israel Deaconess Medical Center, Harvard Medical School, Pancreas and Liver Institute, Boston, MA.

MINI: Cohort study (n = 237) describing a training program to teach robot-assisted distal pancreatectomy to surgeons at an academic institution and assess its impact on outcomes. After training, perioperative blood loss and length of stay improved, while complication rates remained unchanged. Propensity-score matching confirmed a 2-day reduction in length of stay after RADP. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003291DOI Listing

Influence of Preoperative Oropharyngeal Microflora on the Occurrence of Postoperative Pneumonia and Survival in Patients Undergoing Esophagectomy for Esophageal Cancer.

Ann Surg 2019 Mar 28. Epub 2019 Mar 28.

Department of Gastroenterological Surgery, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

MINI: We investigated the influence of the preoperative oropharyngeal microflora on the outcomes of patients undergoing esophagectomy for esophageal cancer. The existence of allopatric antibiotic-resistant flora was an independent predictor of postoperative pneumonia. In addition, the long-term survival of patients with such microbes in their oropharynx was significantly worse than those without. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003287DOI Listing
March 2019
4 Reads
8.327 Impact Factor

Facilitation of Surgical Innovation: Is It Possible to Speed the Introduction of New Technology While Simultaneously Improving Patient Safety?

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

MINI: Future advancement of the field of surgery is dependent on its ability to safely implement innovative devices and procedures. This study describes a structured institutional approach to the introduction of surgical innovations that improved efficiency and patient safety, and is transferrable to other centers.

Objective: To review efficiency metrics and patient safety data before and after implementation of a structured review process for surgical innovations. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003290DOI Listing
March 2019
4 Reads

Conditional Survival in Patients With Rectal Cancer and Complete Clinical Response Managed by Watch and Wait After Chemoradiation: Recurrence Risk Over Time.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Angelita & Joaquim Gama Institute, Sao Paulo, Brazil.

MINI: Organ-preservation has become an attractive alternative to select patients with rectal cancer. Conditional recurrence-free survival analyses suggest that the risk of recurrence after 2 years of successful organ-preservation is significantly low (<10%). Risk of recurrence over time may represent valuable information for surveillance strategies among these patients. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003286DOI Listing
March 2019
3 Reads

Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Harvard Medical School, Boston, MA.

MINI: In this manuscript, the ability of SOMAscan technology to identify proteins differentially expressed before and after surgery in older adults was evaluated. Systems biology analyses demonstrated that inflammatory proteins and biological functions associated with the inflammatory response and immune cell regulation demonstrated the greatest changes after surgery.

Objectives: To characterize the proteomic signature of surgery in older adults and association with postoperative outcomes. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003283DOI Listing
March 2019
3 Reads

System Factors Affecting Intraoperative Risk and Resilience: Applying a Novel Integrated Approach to Study Surgical Performance and Patient Safety.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

International Centre for Surgical Safety, Keenan Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada.

MINI: A prospective descriptive study of factors affecting patient safety in laparoscopic general surgery. Using video-based observation and a qualitative systems approach, intraoperative human factors with the potential to either threaten patient safety or support system resilience during unanticipated disturbances in care were identified.

Objective: To identify and categorize system factors in complex laparoscopic surgery that have the potential to either threaten patient safety or support system resilience. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003280DOI Listing

Impact of Oral Immunonutrition on Postoperative Morbidity in Digestive Oncologic Surgery: A Nation-Wide Cohort Study.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Assistance Publique - Hôpitaux de Paris, Hôpital européen Georges-Pompidou, Service de nutrition, Centre Spécialisé Obésité France, France.

MINI: Immunonutrition is prescribed systematically before major oncologic surgery to treat a potential malnutrition according to international guidelines. The preoperative use of immunonutrition is based on a decrease of infection and length of hospital stay after surgery. We report no association between immunonutrition and postoperative morbidity neither on infectious complications. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003282DOI Listing
March 2019
1 Read

Eliminating Institutional Barriers to Career Advancement for Diverse Faculty in Academic Surgery.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Department of Surgery, The University of Michigan Medicine, Ann Arbor, MI.

: There is critical need to address achievement barriers in Academic Medicine. Although opportunities for professional development of women and underrepresented minority physician scientists are growing, academic promotion rates remain historically low. Moreover, underrepresented groups are not likely to advance to decanal and leadership positions. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003273DOI Listing

Comment on "Robot-assisted Versus Laparoscopic Surgery for Rectal Cancer: A Phase II Open Label Prospective Randomized Controlled Trial".

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Ospedali Riuniti Marche Nord, Pesaro, Italy Misericordia Hospital, Grosseto, Italy.

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http://dx.doi.org/10.1097/SLA.0000000000003267DOI Listing
March 2019
4 Reads

Tumor Long-interspersed Nucleotide Element-1 Methylation Level and Immune Response to Esophageal Cancer.

Ann Surg 2019 Mar 26. Epub 2019 Mar 26.

Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan.

MINI: Tumor long-interspersed nucleotide element-1 (LINE-1) hypomethylation level is associated with a diminished peritumoral lymphocytic reaction in esophageal cancer tissues. Our human population-based study provides impetus for further investigations on potential interactive roles of tumor LINE-1 hypomethylation and host immunity in esophageal cancer development.

Objective: To examine the relationship between tumor long-interspersed nucleotide element-1 (LINE-1) methylation level and immune response to esophageal cancer. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003264DOI Listing
March 2019
1 Read

Integrated Physiological and Biochemical Assessments for the Prediction of Growth of Abdominal Aortic Aneurysms in Humans.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Surgery, Section of Vascular Surgery, Michigan Medicine, Ann Arbor, MI Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1097/SLA.0000000000003298DOI Listing
April 2019
1 Read

Endovascular Aneurysm Repair With Inferior Mesenteric Artery Embolization for Preventing Type II Endoleak: A Prospective Randomized Controlled Trial.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Minami-kogushi, Ube, Japan.

Objective: This study aimed to evaluate the effect of inferior mesenteric artery (IMA) embolization during endovascular aneurysm repair (EVAR) in patients at high risk of type II endoleak (T2EL) in randomized controlled trial (RCT).

Summary Background Data: Several studies have demonstrated a reduction of T2EL by IMA embolization before EVAR. However, there have been no RCT confirming the efficacy of IMA embolization. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003299DOI Listing
April 2019
6 Reads

Outcome of 1000 Patients With Gastrointestinal Stromal Tumor (GIST) Treated by Surgery in the Pre and Post-imatinib Eras.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

MINI: In the pre-imatinib era, primary tumor site, size, and mitotic rate predicted outcome as expected. In the modern era, survival was dramatically longer. While primary tumor high-risk features were associated with imatinib treatment, only tumor size >10 cm remained associated with outcome. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003277DOI Listing
April 2019
3 Reads
8.327 Impact Factor

Response: Comment on the Study by Melkemichel: Long-term Comparison of Recurrence Rates Between Different Lightweight and Heavyweight Meshes in Open Anterior Mesh Inguinal Hernia Repair-A Nationwide Population-based Register Study.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Berlin, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003311DOI Listing
April 2019
1 Read

A Study on Radial Margin Status in Resected Perihilar Cholangiocarcinoma.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

MINI: This study investigated radial margin status in 478 patients who underwent hepatectomy for perihilar cholangiocarcinoma. Positive radial margin status was the most common cause for R1 resection and had similarly negative effects on postoperative survival similar as positive ductal margin status.

Objective: To investigate radial margin (RM) status in resected perihilar cholangiocarcinoma (PHCC) and to evaluate the incidence of positive RM and its effect on survival. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003305DOI Listing
April 2019
3 Reads

Surgery Improves Survival After Neoadjuvant Therapy for Borderline and Locally Advanced Pancreatic Cancer: A Single Institution Experience.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Clinical Science, Intervention, and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden.

MINI: The overall survival and the survival after resection of patients with borderline resectable pancreatic cancer or locally advanced pancreatic cancer after neoadjuvant therapy (NAT) are similar. Resected patients had better survival than nonresected, irrespective of the type or whether full-dose NAT was given. For all preoperative values of Ca 19-9, surgical resection had positive impact on survival. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003301DOI Listing
April 2019
1 Read

Understanding the Barriers to Reporting Sexual Harassment in Surgical Training.

Ann Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Surgery, Yale School of Medicine, New Haven, CT.

Objective: To investigate the occurrence, nature, and reporting of sexual harassment in surgical training and to understand why surgical trainees who experience harassment might not report it. This information will inform ways to overcome barriers to reporting sexual harassment.

Summary/ Background Data: Sexual harassment in the workplace is a known phenomenon with reports of high frequency in the medical field. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003295DOI Listing
April 2019
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Drain Management Following Distal Pancreatectomy: Characterization of Contemporary Practice and Impact of Early Removal.

Ann Surg 2019 Jan 30. Epub 2019 Jan 30.

Department of Surgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.

MINI: Early drain removal has yet to be explored following distal pancreatectomy. Following analysis of ACS-NSQIP data, early removal demonstrated significantly better outcomes when compared to late removal and drain omission. Multivariable analysis revealed early removal had reduced odds for pancreatic fistula and death or serious morbidity compared to drain omission, while late drain removal conversely displayed increased odds. Read More

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http://dx.doi.org/10.1097/SLA.0000000000003205DOI Listing
January 2019

Comment on "US FDA Breast Implant Post Approval Studies. Longterm Outcomes in 99,993 Patients".

Ann Surg 2019 Mar 20. Epub 2019 Mar 20.

University of Milan, Milan, Italy Group for Reconstructive and Therapeutic Advancements (GRETA), Milan, Naples, Catania, Italy Group for Reconstructive and Therapeutic Advancements (GRETA), Milan, Naples, Catania, Italy Multidisciplinary Breast Unit, Azienda Ospedaliera Cannizzaro, Catania, Italy Group for Reconstructive and Therapeutic Advancements (GRETA), Milan, Naples, Catania, Italy Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.

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http://dx.doi.org/10.1097/SLA.0000000000003294DOI Listing