2,437 results match your criteria Ann Transl Med[Journal]


A comparison of peri-operative outcomes between elective and non-elective total hip arthroplasties.

Ann Transl Med 2019 Feb;7(4):78

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY, USA.

Background: Elective total hip arthroplasties (THAs) entail a more extensive pre-operative planning process compared to non-elective THAs and this may contribute to a disparity in outcomes. However, the differences in peri- and post-operative outcomes between elective and non-elective THAs remain unclear. Therefore, the purpose of this study was to: (I) determine nationwide trends in operative times and (II) evaluate the association between surgery type, elective or non-elective with respect to (I) operative times; (II) hospital lengths-of-stay (LOS); (III) discharge disposition; (IV) 30-day post-operative complications; (V) reoperations; and (VI) readmissions. Read More

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http://dx.doi.org/10.21037/atm.2019.01.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409228PMC
February 2019
1 Read

Mortality after hip resurfacing versus total hip arthroplasty in young patients: a single surgeon experience.

Ann Transl Med 2019 Feb;7(4):77

Department of Orthopaedic Surgery, Lenox Hill Hospital, New York, NY, USA.

Background: The aims of this study were to investigate the following questions: (I) what are the mortality rates in patients age 55 years and younger who underwent a hip resurfacing arthroplasty (HRA) versus a standard total hip arthroplasty (THA)? (II) is the type of operation independently associated with mortality?

Methods: The database of a single high-volume surgeon was reviewed for patient's age 55 years and younger who underwent a hip arthroplasty between 2002 and 2010. This yielded 505 HRA patients and 124 THA patients. Chi-square analysis was performed to identify a 5-year mortality rate difference between the two cohorts. Read More

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http://dx.doi.org/10.21037/atm.2019.01.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409229PMC
February 2019
1 Read

A 6-year trends analysis of infections after revision total hip arthroplasty.

Ann Transl Med 2019 Feb;7(4):76

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY, USA.

Background: Substantial efforts have been made to reduce the risk of infection after total hip arthroplasty (THA), including pre-operative patient optimization, skin preparation with alcohol-based solutions, perioperative antibiotics, and minimizing wound drainage with novel sutures and dressings. While these approaches have been effective in primary THA, their effects on revision THA to improve surgical site infection (SSI) rates are less clear. Therefore, the purpose of this study was to identify the annual rates and trends of: (I) overall; (II) deep; and (III) superficial SSIs following revision THA using the most recent results (2011 to 2016) from a large, nationwide database. Read More

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http://dx.doi.org/10.21037/atm.2019.01.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409237PMC
February 2019

Use of an offset head center acetabular shell in difficult primary total hip arthroplasties.

Ann Transl Med 2019 Feb;7(4):75

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.

Several conditions may predispose patients to development of antero-lateral acetabular bone deficiency, including developmental dysplasia of the hip, osteonecrosis, or septic arthritis, among others. This may compromise the ability to gain acetabular component stability and impair reliable fixation. Large acetabular shells have often been used to achieve adequate fixation in scenarios of severe bone loss, however, these techniques have been shown to elevate the center of rotation (COR) of the hip and alter hip biomechanics. Read More

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http://dx.doi.org/10.21037/atm.2018.09.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409236PMC
February 2019
2 Reads

Not all primary total hip arthroplasties are equal-so is there a difference in reimbursement?

Ann Transl Med 2019 Feb;7(4):74

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY, USA.

Background: Relative value units (RVUs) are a physician reimbursement model based on the effort required, or value, in providing a procedure or service for a patient. Procedures such as conversion total hip arthroplasties (THAs) can be compared to primary THAs, but many studies have revealed increased difficulties in conversion cases. Despite the increased time and effort for conversion THA, it is unknown if this is reflected in the RVU compensation model. Read More

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http://dx.doi.org/10.21037/atm.2018.08.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409238PMC
February 2019

Routine use of commercial antibiotic-loaded bone cement in primary total joint arthroplasty: a critical analysis of the current evidence.

Ann Transl Med 2019 Feb;7(4):73

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.

Antibiotic-loaded cement (ABLC) has been widely utilized as an adjuvant treatment for patients with periprosthetic joint infection (PJI) but has also evolved to play a prophylactic role against infection in primary total joint arthroplasties (TJA). Nevertheless, there is currently a paucity of studies that systematically investigated this concept. This review aimed at answering the following questions: (I) Can routine use of ABLC help reduce the current infection rates in primary TJA? (II) What are the risks associated with this approach? And (III) can routine use be justified in primary TJA from an economic standpoint? Multiple databases were queried including PubMed, EMBASE, EBSCO Host, and SCOPUS. Read More

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http://dx.doi.org/10.21037/atm.2018.11.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409235PMC
February 2019

Quadriceps tendinopathy: a review, part 2-classification, prognosis, and treatment.

Ann Transl Med 2019 Feb;7(4):72

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.

Overuse injuries of the extensor mechanism of the knee are common in both athletes and non-athletes and usually occur during activities associated with repetitive loading, stress, and knee extension. Numerous reports have been published describing extensor mechanism injuries in athletes, but there is a paucity of studies that focus on quadriceps tendinopathy in the non-athlete population. In addition, there is no universally accepted classification system for tendon pathology. Read More

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http://dx.doi.org/10.21037/atm.2019.01.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409233PMC
February 2019
2 Reads

Quadriceps tendinopathy: a review-part 1: epidemiology and diagnosis.

Ann Transl Med 2019 Feb;7(4):71

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA.

Overuse injuries of the extensor mechanism of the knee are common in both athletes and non-athletes and usually occur during activities associated with repetitive loading, stress, and knee extension. Historically, they have been labeled as Jumper's knee due to the high prevalence seen in the athletic community. In many published reports, the name "patellar tendinopathy" is used to describe this disorder of the quadriceps tendon at the patellar insertion, and the names are often used interchangeably. Read More

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http://dx.doi.org/10.21037/atm.2019.01.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409230PMC
February 2019
1 Read

Astym therapy: a systematic review.

Ann Transl Med 2019 Feb;7(4):70

Department of Orthopaedic Surgery, Lenox Hill Hospital, New York, NY, USA.

Soft tissue dysfunction can result from the degeneration of tissues as in the case of degenerative tendinopathy or from the build-up of problematic scar tissue, which can be the result of several aggravating factors, including overuse injuries, acute or chronic trauma, or as a result of surgery. This dysfunction often results in impaired movement, pain, and swelling of the affected area, which can lead to patient dissatisfaction and a lower quality of life. These soft tissue dysfunctions also have a marked economic impact. Read More

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http://dx.doi.org/10.21037/atm.2018.11.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409241PMC
February 2019
3 Reads

Impact of early mobilization on length of stay after primary total knee arthroplasty.

Ann Transl Med 2019 Feb;7(4):69

University of Louisville Adult Reconstruction Program, Louisville, KY, USA.

Background: Decreasing length of stay (LOS) following primary total knee arthroplasty (TKA) has been an important focus by all the stakeholders involved in the delivery of care. LOS is dictated by both the patient and hospital-related factors. The purpose of this study was to determine if early mobilization on post-operative day 0 (POD 0) following primary TKA has an effect on hospital LOS and discharge to home rehabilitation facilities. Read More

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http://atm.amegroups.com/article/view/24043/22779
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http://dx.doi.org/10.21037/atm.2019.02.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409239PMC
February 2019
7 Reads

The role of prehabilitation with a telerehabilitation system prior to total knee arthroplasty.

Ann Transl Med 2019 Feb;7(4):68

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA.

Background: The purpose of the current study was to evaluate the usage of prehabilitation on a telehealth platform prior to total knee arthroplasty (TKA) and its impact on short-term outcomes. Specifically, the study examined whether patients participating in a prehabilitation program impacted length of stay (LOS) and discharge disposition.

Methods: A total of 476 consecutive patients who underwent TKA at three institutions were included. Read More

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http://dx.doi.org/10.21037/atm.2018.11.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409240PMC
February 2019

Patient satisfaction and outcomes of static progressive stretch bracing: a 10-year prospective analysis.

Ann Transl Med 2019 Feb;7(4):67

Department of Orthopaedic Surgery, Lenox Hill Hospital, New York, NY, USA.

Background: Multiple surgical and non-surgical modalities are available for patients suffering from shoulder elbow, forearm, wrist, knee and ankle stiffness. For most patients, bracing can provide optimal therapy to restore functional range of motion (ROM). Three commonly used bracing mechanisms include static progressive stretch (SPS), turnbuckle, and dynamic bracing. Read More

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http://atm.amegroups.com/article/view/21271/22777
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http://dx.doi.org/10.21037/atm.2018.08.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409232PMC
February 2019
4 Reads

The effect of operative time on in-hospital length of stay in revision total knee arthroplasty.

Ann Transl Med 2019 Feb;7(4):66

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY, USA.

Background: Revision total knee arthroplasty (TKA) is associated with increased rates of infections, readmissions, longer operative times, and lengths-of-stay (LOS) compared to primary TKA. Additionally, increasing operative times and prolonged postoperative LOS are independent risk factors for these postoperative complications in lower extremity total joint arthroplasty (TJA). This has led to an increased effort to reduce these risk factors in order to improve patient outcomes and reduce cost. Read More

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http://dx.doi.org/10.21037/atm.2019.01.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409231PMC
February 2019
1 Read

Discharge to the skilled nursing facility: patient risk factors and perioperative outcomes after total knee arthroplasty.

Ann Transl Med 2019 Feb;7(4):65

Department of Orthopedic Surgery, Lenox Hill Hospital, New York City, NY, USA.

Background: Patients receiving a total knee arthroplasty (TKA) who fail to meet inpatient criteria for outpatient physical therapy or an acute rehabilitation facility are increasingly being discharged to skilled nursing facilities (SNFs). However, in some facilities, postoperative care and therapy may be suboptimal. In order to recognize the circumstances predisposing patients to a SNF discharge and quantify perioperative risks, we used a nationwide TKA database to compare those who were and were not discharged to SNFs with respect to: (I) patient and hospital characteristics; (II) comorbidities; (III) lengths of stay (LOS); and (IV) inpatient complications. Read More

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http://dx.doi.org/10.21037/atm.2018.12.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409242PMC
February 2019
1 Read

A nationwide comparative analysis of medical complications in fibromyalgia patients following total knee arthroplasty.

Ann Transl Med 2019 Feb;7(4):64

Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY, USA.

Background: Fibromyalgia is a disease primarily characterized by chronic widespread pain and associated symptoms of fatigue, mild cognitive impairment, and sleep disturbance. The condition affects 1% to 6% of the general population in the United States and is more commonly diagnosed in women (2:1 ratio). There is evidence to suggest that fibromyalgia patients may be more at risk of postoperative complications. Read More

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http://atm.amegroups.com/article/view/23335/22774
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http://dx.doi.org/10.21037/atm.2018.12.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409227PMC
February 2019
7 Reads

Lower extremity arthroplasty.

Ann Transl Med 2019 Feb;7(4):63

Lenox Hill Hospital, Northwell Health, New York, NY, USA.

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http://atm.amegroups.com/article/view/23921/22773
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http://dx.doi.org/10.21037/atm.2019.01.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409234PMC
February 2019
4 Reads

Minimally invasive segmentectomy for early stage lung cancer gains momentum.

Ann Transl Med 2019 Feb;7(3):62

Division of Cardiothoracic Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.

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http://dx.doi.org/10.21037/atm.2018.12.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389575PMC
February 2019

Central nervous system activity of first-line osimertinib in epidermal growth factor receptor-mutant advanced non-small cell lung cancer.

Authors:
Chong-Kin Liam

Ann Transl Med 2019 Feb;7(3):61

Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.21037/atm.2018.12.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389567PMC
February 2019
1 Read

Timely renal transplantation for scleroderma end-stage kidney disease patients can improve outcomes and quality of life.

Ann Transl Med 2019 Feb;7(3):60

Department of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.21037/atm.2018.12.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389581PMC
February 2019

Pro-tumoral role of gut bacteria: sabotaging immune cell recruitment.

Ann Transl Med 2019 Feb;7(3):59

Department of Surgery, Ente Ospedaliero Cantonale and Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.

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http://dx.doi.org/10.21037/atm.2018.12.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389571PMC
February 2019

GABA strikes down again in epilepsy.

Ann Transl Med 2019 Feb;7(3):57

Pediatric Neurology and Muscular Diseases Unit, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, "G. Gaslini" Institute, Genova, Italy.

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http://atm.amegroups.com/article/view/23300/22570
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http://dx.doi.org/10.21037/atm.2018.12.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389577PMC
February 2019
4 Reads

Improving the diagnosis of renal masses: can we approach the histological diagnosis to the image?

Ann Transl Med 2019 Feb;7(3):56

Department of Urology, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.

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http://dx.doi.org/10.21037/atm.2018.12.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389568PMC
February 2019

Hyperphosphatemia: a novel risk factor for mortality in chronic kidney disease.

Ann Transl Med 2019 Feb;7(3):55

Renal Division and Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, Milan, Italy.

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http://atm.amegroups.com/article/view/20232/22568
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http://dx.doi.org/10.21037/atm.2018.06.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389588PMC
February 2019
3 Reads

Aprepitant for gefitinib-induced refractory pruritus in Chinese malignancy population.

Ann Transl Med 2019 Feb;7(3):54

Department of Pulmonary Neoplasm Internal Medicine, 307 Hospital of PLA, Beijing 100000, China.

Targeted therapy is an important anti-cancer therapy in non-small cell lung cancer (NSCLC). Pruritus are the common side-effect with gefitinib, an anti-EGFR antibody and tyrosine-kinase inhibitor. We reported case reports to confirm the effects of aprepitant, a neurokinin receptor to management of refractory rash and pruritus in Chinese malignancy population. Read More

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http://dx.doi.org/10.21037/atm.2019.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389580PMC
February 2019
2 Reads

Cardiac penetrating injury: a rare complication associated with the lung nodule localization by hookwire.

Ann Transl Med 2019 Feb;7(3):53

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.

A 48-year-old woman with small lung nodule received transthoracic lung nodule localization by hookwire and subsequent lung resection. At the time of lung nodule localization, computed tomography (CT) scan showed that the localization was successful without any complication. However, cardiac penetrating injury caused by hookwire localizer was unexpectedly observed during surgery. Read More

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http://dx.doi.org/10.21037/atm.2018.12.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389587PMC
February 2019

A rare presentation of pleomorphic carcinoma of lung mimic empyema.

Ann Transl Med 2019 Feb;7(3):52

School of Medicine, National Yang-Ming University, Taipei, Taiwan.

Pleomorphic carcinoma (PC) of lung, a rare malignant lung tumor, is predominated in male smokers with over 65 years of age. The clinical presentations of PC are various including chest pain, cough, and dyspnea and so on. Asymptomatic patients have been also reported. Read More

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http://dx.doi.org/10.21037/atm.2018.12.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389579PMC
February 2019
1 Read

Rare paraneoplastic erythroderma associated with ectopic neuron-specific enolase deposition in basal cells.

Ann Transl Med 2019 Feb;7(3):51

Department of Thoracic Surgery, Tangdu Hospital, the Fourth Military Medical University, Xi'an 710038, China.

The cutaneous symptom of the paraneoplastic erythroderma can be the only symptom of a malignancy. Although many cases associated with malignancies have been reported, the pathogenesis of cancer related erythroderma is still unclear. Herein we presented a patient with large cell neuroendocrine carcinoma (LCNEC) of the lung and contemporary severe erythroderma. Read More

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http://dx.doi.org/10.21037/atm.2018.12.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389566PMC
February 2019
2 Reads

Left lower lobe sleeve resection for endobronchial schwannoma.

Ann Transl Med 2019 Feb;7(3):50

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Schwannomas are mesenchymal neoplasms originating from Schwann cells of the nerve sheath. The tumor may appear anywhere in the body, while it has a predilection for extremities, trunk, retroperitoneum, head, and neck. Primary pulmonary schwannoma is extremely rare, accounting for less than 0. Read More

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http://dx.doi.org/10.21037/atm.2018.12.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389569PMC
February 2019
3 Reads

Role of bronchoalveolar lavage in the management of immunocompromised patients with pulmonary infiltrates.

Ann Transl Med 2019 Feb;7(3):49

Singapore Health Services, Singapore.

Pulmonary infiltrates are a significant cause of morbidity and mortality in immunocompromised patients and remain a diagnostic challenge due to the broad range of etiologies that include infection and malignancy. Empiric therapy may be sub-optimal and can adversely impact outcome. Therefore, a confirmed diagnosis is necessary and flexible bronchoscopy with bronchoalveolar lavage (BAL) may be a useful diagnostic tool. Read More

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http://dx.doi.org/10.21037/atm.2019.01.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389578PMC
February 2019
1 Read

Short-term outcomes after anatomic total shoulder arthroplasty in patients with osteoarthritis versus osteonecrosis.

Ann Transl Med 2019 Feb;7(3):48

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Background: The outcomes of anatomic total shoulder arthroplasty (TSA) for glenohumeral osteoarthritis (OA) have been extensively reported in the literature. However, there is a paucity of short-term outcomes data on perioperative and post-operative outcomes in patients receiving TSA for either glenoid or humeral head osteonecrosis (ON). We compared the short-term outcomes of TSA performed on patients who had glenohumeral OA and those who had ON. Read More

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http://dx.doi.org/10.21037/atm.2018.12.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389584PMC
February 2019
1 Read

An evaluation of adult critical result policies in haematology in a teaching hospital in China.

Ann Transl Med 2019 Feb;7(3):47

School of Nursing, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Background: Critical result (CR) reporting is one of the core policies in China, yet it varies in different hospitals. In addition, few reports of the evaluation of CR policies have been published. This study aimed to evaluate the adult CR policies for haematology in a teaching hospital. Read More

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http://dx.doi.org/10.21037/atm.2019.01.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389582PMC
February 2019

Predictors of blood transfusion and in-hospital outcomes in patients with gastric antral vascular ectasia (GAVE): a nationwide population-based analysis.

Ann Transl Med 2019 Feb;7(3):46

Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA.

Background: Gastric antral vascular ectasia (GAVE) is a rare cause of chronic non-variceal upper gastrointestinal (GI) bleeding and can turn into life-threatening bleed in some patients. Packed red blood cell (PRBC) transfusions are often required in these patients during hospitalization. We aimed to investigate the hospitalization outcomes and predictors of PRBC transfusions in patients with GAVE lesions. Read More

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http://dx.doi.org/10.21037/atm.2019.01.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389573PMC
February 2019
1 Read

Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis.

Ann Transl Med 2019 Feb;7(3):45

Thyroid Disease Diagnosis and Treatment Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.

Background: Subacute thyroiditis (SAT) is a self-limited disease commonly treated with prednisolone (PSL). The present study aimed to assess the effectiveness and safety of the new treatment protocol which consisted of PSL and Prunella vulgaris (PV) to reduce the dosage and incidence of side effects from PSL.

Methods: Data regarding the patients with SAT treated at the First Affiliated Hospital, School of Medicine, Zhejiang University between September 2013 and May 2016 were retrospectively analyzed. Read More

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http://dx.doi.org/10.21037/atm.2019.01.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389583PMC
February 2019
1 Read

Predictive risk factors of acute kidney injury after on-pump coronary artery bypass grafting.

Ann Transl Med 2019 Feb;7(3):44

Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

Background: Acute kidney injury (AKI) is a common complication after coronary artery bypass grafting (CABG) and increases the risk of short and long-term morbidity and mortality. The aim of our study is to identify preoperative and intraoperative risk factors for development of AKI after primary isolated on-pump CABG.

Methods: In the retrospective study, 210 consecutive patients who underwent primary isolated on-pump CABG from January 2007 to March 2016 were included. Read More

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http://dx.doi.org/10.21037/atm.2018.12.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389572PMC
February 2019
1 Read

Pulmonary nodular lymphoid hyperplasia: a rare benign disease with malignant mask.

Ann Transl Med 2019 Feb;7(3):43

Department of Thoracic Surgery, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Background: Pulmonary nodular lymphoid hyperplasia (PNLH) is a rare benign disease lacking systematically clinical assessment. This study aims to explore the clinical features of PNLH and evaluate the safety and efficacy of different surgical approaches for PNLH.

Methods: Patients with confirmed PNLH in our department between March 2007 and August 2017 were retrospectively reviewed. Read More

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http://dx.doi.org/10.21037/atm.2018.12.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389570PMC
February 2019

Receptor-interacting protein kinase 3 as a predictive adjuvant chemotherapy marker after lung adenocarcinoma resection.

Ann Transl Med 2019 Feb;7(3):42

Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea.

Background: This study assessed the predictive value of receptor-interacting protein kinase 3 (RIPK3) expression and its correlation with clinicopathological characteristics, disease-free survival, and overall survival of patients with cisplatin-based adjuvant chemotherapy after lung adenocarcinoma resection.

Methods: This study included 50 patients who underwent cisplatin-based adjuvant chemotherapy after lung adenocarcinoma (stage IB-IIIA) resection. Immunohistochemical analysis was performed by probing tumor tissue microarrays with anti-RIPK3 antibody. Read More

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http://dx.doi.org/10.21037/atm.2018.12.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389586PMC
February 2019

Medium-term outcome of cementless, mobile-bearing, unicompartmental knee arthroplasty.

Ann Transl Med 2019 Feb;7(3):41

Orthopedic Surgery Department of Promienista Clinic, Poznan, Poland.

Background: Cemented, mobile-bearing unicondylar knee arthroplasty (UKA) yields good functional results. However, radiolucent lines (RLL) are not uncommon, even in asymptomatic patients, and it has been debated whether these "physiological" RLLs are indicative of loosening. Cementless UKA may lead to fewer RLLs compared with cemented devices. Read More

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http://dx.doi.org/10.21037/atm.2018.12.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389574PMC
February 2019
1 Read

Non-intubated thoracoscopic surgery for lung cancer in patients with impaired pulmonary function.

Ann Transl Med 2019 Feb;7(3):40

Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: Patients with impaired lung function or chronic obstructive pulmonary disease (COPD) are considered high-risk for intubated general anesthesia, which may preclude them from surgical treatment of their lung cancers. We evaluated the feasibility of non-intubated video-assisted thoracoscopic surgery (VATS) for the surgical management of lung cancer in patients with impaired pulmonary function.

Methods: From August 2009 to June 2015, 28 patients with impaired lung function (preoperative forced expiratory volume in 1 second <70% of the predicted value) underwent non-intubated VATS using a combination of thoracic epidural anesthesia or intercostal nerve block, and intra-thoracic vagal block with target-controlled sedation. Read More

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http://atm.amegroups.com/article/view/22707/22553
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http://dx.doi.org/10.21037/atm.2018.11.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389589PMC
February 2019
3 Reads

High performance of intravoxel incoherent motion diffusion MRI in detecting viral hepatitis-b induced liver fibrosis.

Ann Transl Med 2019 Feb;7(3):39

Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

Background: Recently a small cohort study demonstrated that intravoxel incoherent motion (IVIM) diffusion MRI can detect early stage liver fibrosis. Using modified IVIM data acquisition parameters, the current study aims to confirm this finding.

Methods: Twenty-six healthy volunteers, three patients of chronic viral hepatitis-b but without fibrosis and one mild liver steatosis subject, and 12 viral hepatitis-b patients with fibrosis (stage 1-2=7, stage 3-4=5) were included in this study. Read More

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http://dx.doi.org/10.21037/atm.2018.12.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389585PMC
February 2019
1 Read

Clarification of the resection line non-intubated segmentectomy using indocyanine green.

Ann Transl Med 2019 Jan;7(2):38

Department of Surgery, Resuscitation, and Intensive Care, Faculty of Medicine, Masaryk University Brno, University Hospital Brno, Bohunice, Czech Republic.

A reflection on the measure of fluorescence specificity of indocyanine green (ICG) in non-intubated pulmonary segmentectomy. Read More

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http://dx.doi.org/10.21037/atm.2019.01.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381263PMC
January 2019

Ultrasound for intraoperative localization of lung nodules during thoracoscopic surgery.

Ann Transl Med 2019 Jan;7(2):37

Department of Surgery, National Taiwan University Hospital and National Taiwan University, College of Medicine, Taipei, Taiwan.

In low-dose CT screening era, an ideal preoperative localization method is essential for resection of small and deep-seated pulmonary nodules by video-assisted thoracoscopic surgery (VATS). This article focuses on intraoperative ultrasonography localization method during thoracoscopy. Performing ultrasonography intraoperatively is a real-time and alternative approach to localize small, non-visible and non-palpable pulmonary lesions without injury to lung parenchyma. Read More

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http://dx.doi.org/10.21037/atm.2019.01.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381266PMC
January 2019

Latest update about virtual-assisted lung mapping in thoracic surgery.

Ann Transl Med 2019 Jan;7(2):36

Department of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.

Virtual-assisted lung mapping (VAL-MAP) is a preoperative bronchoscopic multi-spot dye-marking technique using virtual images developed to assist in navigational lung resection. The technique of VAL-MAP has been shown to be safe and effective surgical assistive tool for performing pulmonary sublobar resections. The technique is applicable for treating multiple small pulmonary lesions that are hardly palpable including ground glass nodules (GGNs). Read More

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http://atm.amegroups.com/article/view/23292/22603
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http://dx.doi.org/10.21037/atm.2018.12.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381264PMC
January 2019
4 Reads

Latest technology in minimally invasive thoracic surgery.

Ann Transl Med 2019 Jan;7(2):35

Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.

From the introduction of video-assisted thoracoscopic surgery (VATS) in the 1990s, to performing major lung resections using a uniportal VATS approach, technology has paved the way for the development of minimally invasive thoracic surgery. Natural orifice access to achieve a 'no port' approach, is also on the rise, with advancements in bronchoscopic techniques for diagnosis and therapy, as well as development of soft robotics to achieve desired flexibility, dexterity and stability in future platforms, which may involve deployment to bring the surgeon totally inside the body. Development of haptic feedback in robotic platforms to enhance the surgical experience is also a major goal, with vibrotactile and mechanical feedback generation, to replicate the traditional touch. Read More

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http://atm.amegroups.com/article/view/23118/22602
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http://dx.doi.org/10.21037/atm.2018.12.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381267PMC
January 2019
4 Reads

Hybrid operating room for the intraoperative CT-guided localization of pulmonary nodules.

Ann Transl Med 2019 Jan;7(2):34

Division of Thoracic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Video-assisted thoracic surgery (VATS) requires preoperative computed tomography (CT)-guided localization of small pulmonary nodules or ground glass opacities (GGOs). However, this traditional two-stage approach is not devoid of potential complications, including wire dislodgement, pneumothorax, and/or hemothorax. With the advent of hybrid operating rooms (HORs), simultaneous single-stage localization and removal of such lesions has become possible. Read More

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http://dx.doi.org/10.21037/atm.2018.12.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381269PMC
January 2019

Prediction of pleural invasion using different imaging tools in non-small cell lung cancer.

Ann Transl Med 2019 Jan;7(2):33

Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Clinical staging of non-small cell lung cancer (NSCLC) is used for planning therapeutic strategies. In particular, pleural invasion is regarded as an indicator for upstaging to T2 or T3 in the current 8th TNM staging system; patients with pleural invasion should be indicated for lobectomy rather than sublobar resection. Therefore, accurate preoperative prediction of pleural invasion is important for surgical planning. Read More

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http://dx.doi.org/10.21037/atm.2019.01.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381262PMC
January 2019
3 Reads

Recent fluorescence-based optical imaging for video-assisted thoracoscopic surgery segmentectomy.

Ann Transl Med 2019 Jan;7(2):32

Department of Thoracic Surgical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Background: The importance of fluorescence-based optical imaging in various fields of surgery is increasing. This is a prospective cohort study aimed to investigate the feasibility and efficacy of indocyanine-green fluorescence (ICGF)-based navigation for near-infrared (NIR) thoracoscopic segmentectomy.

Methods: ICGF-based video-assisted thoracoscopic surgery (VATS) segmentectomy was performed in 149 patients. Read More

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http://atm.amegroups.com/article/view/23489/22599
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http://dx.doi.org/10.21037/atm.2019.01.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381273PMC
January 2019
4 Reads

Computed tomography-guided dye localization for deeply situated pulmonary nodules in thoracoscopic surgery.

Ann Transl Med 2019 Jan;7(2):31

Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: Increased lung cancer screening of asymptomatic adults using low-dose computed tomography (CT) with high-resolution imaging modalities has increased the identification of small and deeply situated pulmonary nodules. This study aimed to evaluate the role of preoperative patient blue vital (PBV) dye localization for an undiagnosed nodule deeply situated in the lung parenchyma followed by minimally invasive lung resection.

Methods: From July 2013 to December 2016, 27 consecutive patients (16 women, median age: 62 years) with small undiagnosed pulmonary nodules at a depth of more than 30 mm underwent preoperative CT-guided PBV dye localization followed by thoracoscopic diagnostic resection of the nodule at National Taiwan University Hospital. Read More

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http://dx.doi.org/10.21037/atm.2019.01.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381268PMC
January 2019

Single-stage hybrid localization: a combination of bronchoscopic lung mapping followed by post-mapping computed tomographic reconstruction and additional transthoracic needle localization in a cone beam computed tomography room.

Ann Transl Med 2019 Jan;7(2):30

Department of Surgery, National Taiwan University Hospital, Hsin-Chu Branch, Taiwan.

Background: Bronchoscopic lung mapping is a multispot dye-marking technique, which should be performed under real-time fluoroscopic guidance and post-mapping computed tomographic reconstruction. This study aimed to investigate the feasibility of lung mapping followed by post-mapping computed tomography (CT) and additional needle localization in a cone bean CT (CBCT) room.

Methods: Between February 1, 2018 and August 31, 2018, 11 consecutive patients presenting with 14 lung lesions underwent bronchoscopic lung mapping in a CBCT room followed by thoracoscopic surgery. Read More

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http://dx.doi.org/10.21037/atm.2018.10.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381272PMC
January 2019

Quantitative feature analysis of CT images of transbronchial dye markings mimicking true pulmonary ground-glass opacity lesions.

Ann Transl Med 2019 Jan;7(2):29

Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.

Background: Transbronchial dye marking is a preoperative localization technique aiding pulmonary resection. Post-marking computed tomography (CT) is performed to confirm the locations of the actual markings. This study aimed to evaluate the CT images of dye markings that present as ground-glass opacities (GGO), using quantitative feature analysis. Read More

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http://dx.doi.org/10.21037/atm.2018.11.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381271PMC
January 2019