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J Biomech 2021 Jun 11;124:110573. Epub 2021 Jun 11.

School of Kinesiology, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address:

Individuals with transtibial amputation (TTA) walk with greater muscle activity and metabolic costs than non-amputees. Powered prostheses aim to address these deficits by replicating the active function of the biological ankle. The purpose of this study was to determine if people with TTA alter muscle activity when walking with a powered prosthesis, and if this change relates to changes in metabolic costs. Read More

ANZ J Surg 2021 Jun 21. Epub 2021 Jun 21.

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.

Background: Non-melanoma skin cancers (NMSC) are the most common skin cancers worldwide with research establishing that ultraviolet (UV) radiation influences occurrence. However, recent studies about NMSC tumour frequencies suggested high NMSC predilections in low UV-exposed skin regions.

Methods: The 'Human Surface Anatomy Labeling System' was used to define 100 skin regions to map NMSC locations excised at Flinders Medical Centre (FMC) between 1 January 2012 and 31 December 2017. Read More

J Neuromuscul Dis 2021 Jun 16. Epub 2021 Jun 16.

Occupational and Physiotherapy Department, Sahlgrenska University Hospital, Gothenburg, Sweden.

Background: Individuals with myotonic dystrophy type 1 (DM1) are known to stumble and fall, but knowledge is scarce regarding dynamic stability in this disorder.

Objective: To describe disease progress regarding muscle force, dynamic stability and patient reported unintentional falls during a ten-year period, in individuals with DM1.

Methods: Quantification of isometric muscle force in four leg muscle groups and assessment of Timed 10-meter-walk in maximum speed (T10max), Timed Up&Go (TUG) and Step test (STEP) were performed at three occasions in a DM1 cohort, together with self-reported falls. Read More

Phys Sportsmed 2021 Jun 20. Epub 2021 Jun 20.

Department of Nursing and Physiotherapy, University of Salamanca.

There are few Spanish epidemiological studies of basketball injuries, even though it is the second most played sport and the leading sport played by females in Spain. We studied 117 male and female basketball players from ten amateur or professional teams from four leagues in the 2014-2015 season. There were 11. Read More

Vasc Endovascular Surg 2021 Jun 21:15385744211022598. Epub 2021 Jun 21.

Department of biostatistics, 30025Christian Medical College, Vellore, India.

Objective: The use of drug coated balloon (DCB) for angioplasty has shown superior efficacy against plain balloons for treating complex infrainguinal arterial disease. We report and compare the clinical outcomes following application of DCB(Paclitaxel) and plain angioplasty (POBA) in our tertiary care centre.

Methods: A retrospective, single centre analysis of 301 patients with chronic limb-threatening ischemia involving the infrainguinal segment was conducted between September 2014 and September 2018, after approval from the Institutional review board. Read More

Foot Ankle Int 2021 Jun 19:10711007211002508. Epub 2021 Jun 19.

Service de Chirurgie Orthopédique et Traumatologie de l'appareil locomoteur Hôpitaux Universitaires de Genève, Geneva, Switzerland.

Background: Anatomic and clinical studies show many variants of the superficial peroneal nerve (SPN) course and branching within the compartments and at the suprafascial layer. The anatomy of the transition zone from the compartment to the subcutaneous layer has been occasionally described in the literature, mainly in studies reporting the intraseptal SPN variant in 6.6% to 13. Read More

Cureus 2021 May 18;13(5):e15084. Epub 2021 May 18.

Physical Medicine and Rehabilitation, Centre for Musculoskeletal Medicine, Royal Orthopaedic Hospital, Birmingham, GBR.

Background and objective The coronavirus disease 2019 (COVID-19) pandemic has accelerated the shift towards remote consultations in the medical field, including musculoskeletal (MSK) appointments. General practitioner (GP) registrars are now routinely conducting many MSK consultations remotely; however, very little is known of their level of confidence and satisfaction regarding this new and evolving scenario, or how this may impact patient management of patients. In this study, we aimed to understand GP registrars' level of confidence and satisfaction with respect to remote MSK consultations, and the perceived impact on patient management. Read More

Am J Transl Res 2021 15;13(5):5738-5745. Epub 2021 May 15.

Department of Traumatic Surgery, The First Affiliated Hospital of Xinjiang Medical University Urumqi, Xinjiang Uygur Autonomous Region, China.

Objective: To investigate the efficiency of internal fixation with bone grafting after bone transport for treatment in large-segment bone defects of the lower-limbs.

Methods: This prospective study recruited 100 patients with lower limb tibial segmental bone defects, and based on a random number table they were divided into a control group (n=50, simple bone transport surgery) or an observation group (n=50, internal fixation with bone grafting at docking site after bone transport). The fracture healing time, bone healing index, external fixation time in both groups were compared. Read More

Am J Transl Res 2021 15;13(5):5329-5335. Epub 2021 May 15.

First Department of Traumatology and Orthopedics, Zaozhuang Mining Group Zaozhuang Hospital Zaozhuang, Shandong Province, China.

Objective: To investigate the impact of percutaneous poking reduction (PPR) combined with minimally invasive plate internal fixation on foot function and complications of Sanders type II and III calcaneal fractures (CFs).

Methods: In this prospective study, 76 patients with Sanders type II and III CFs were randomly divided into the control group (n=38, "L" incision open reduction and plate internal fixation) and the study group (n=38, PPR combined with minimally invasive plate internal fixation (MIPIF)). The operation related indexes, skin necrosis rate, Gissane angle, Bohler angle, calcaneal height and ankle-hindfoot score before and after the operation were compared between the two groups. Read More

Exp Ther Med 2021 Aug 8;22(2):848. Epub 2021 Jun 8.

Pharmacy Teaching and Research Department, College of Pharmacy, Wannan Medical College, Wuhu, Anhui 241002, P.R. China.

is a traditional Chinese medicine for treating arthritis and bruises. The aim of the present study was to investigate the anti-arthritic activities and possible associated mechanisms of different isolated sites of (DISC) in adjuvant-induced arthritis (AA) rats. The therapeutic effects of the extracts were assessed through changes in body weights, swelling rates, arthritis indexes (AI) and organ indexes. Read More

J Foot Ankle Surg 2021 May 20. Epub 2021 May 20.

Department of Orthopaedics, West Virginia University, Morgantown, WV.

Successful deformity correction utilizing first metatarsophalangeal (MTP) fusion for hallux valgus with concomitant degenerative changes of the first MTP joint is well documented. Currently, there is limited discussion in the literature focusing on triplanar correction of the first MTP arthrodesis. Presented is a novel approach for triplane correction and fusion of the first MTP joint utilizing a biplanar locked plating system. Read More

J Foot Ankle Surg 2021 May 21. Epub 2021 May 21.

Associate Professor, Department of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, TX; Associate Professor, Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch, Galveston, TX. Electronic address:

Charcot neuroarthropathy secondary to diabetes mellitus is a serious complication, requiring specialist management. As a relatively rare pathology bearing similarity to other, more common diseases, it may be misdiagnosed at initial presentation, potentially leading to delays in appropriate management. We conducted a 2-part online survey of primary care physicians within an academic medical institution to assess knowledge of presentation, complications, diagnosis, and treatment of Charcot neuropathy. Read More

J Mot Behav 2021 Jun 20:1-10. Epub 2021 Jun 20.

Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

AbstractsBiofeedback has been effectively implemented to improve the mediation and distribution of joint loads during gait, however, the inability to effectively coordinate lower limb movement by altering loading patterns may increase pathological stress and risk of injury and deleterious joint changes. This study examined the influence cueing an increase or decrease in lower extremity loading has on inter- and intralimb joint coordination during gait, applied herein for 12 persons following anterior cruciate ligament reconstruction across three loading conditions (control, high, and low). Visual biofeedback was presented on a screen via a force-measuring treadmill with targeted changes prescribed based on stride-to-stride peak vertical ground reaction forces bilaterally. Read More

J Mot Behav 2021 Jun 21:1-9. Epub 2021 Jun 21.

Faculty of Health Sciences, Hokkaido University, Sapporo, Japan.

The purpose of this study was to determine how the application of static stretching to ankle plantar flexors affects postural control during maximum forward leaning. Twenty-six volunteer males (age 21.4 ± 1. Read More

Res Sports Med 2021 Jun 20:1-11. Epub 2021 Jun 20.

Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

The aim of this study was to examine the injury profile of Japanese university handball players. In this cross-sectional study, a total of 1017 participants who played in the 2018 Japanese National University Handball Championship were followed. The incidence within the previous year was 0. Read More

ACS Appl Bio Mater 2019 Apr 20;2(5):2116-2124. Epub 2019 May 20.

Department of Chemistry, University of Rochester, Rochester, NY 14627.

Supramolecular hydrogels are emerging as next-generation alternatives to synthetic polymers for drug delivery applications. Self-assembling peptides are a promising class of supramolecular gelator for drug delivery that have been slow to be adopted despite advantages in biocompatibility due to the relatively high cost of producing synthetic peptide hydrogels compared to synthetic polymer gels. Herein we describe the development and use of inexpensive low molecular weight cationic derivatives of phenylalanine (Phe) as injectable hydrogels for delivery of an anti-inflammatory drug, diclofenac, for pain mitigation in a mouse model. Read More

Eur J Orthop Surg Traumatol 2021 Jun 20. Epub 2021 Jun 20.

Department of Orthopaedic Surgery, Center for Hip Preservation, Orthopaedic and Rheumatologic Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

Purpose: We report our experience with a 3D patient-specific instrument (PSI) in an opening-wedge tibial osteotomy for the correction of varus malalignment in a patient with prior anterior cruciate ligament reconstruction. Previous studies have not reported the use of 3D PSI in patients with prior knee surgeries.

Methods: A pre-operative CT was used to create a 3D model of the lower extremity using Bodycad Imager. Read More

Jt Dis Relat Surg 2021 11;32(2):428-436. Epub 2021 Jun 11.

Ankara Şehir Hastanesi Ortopedi ve Travmatoloji Kliniği, 06800 Çankaya, Ankara, Türkiye.

Objectives: This study aims to evaluate the mid-term clinical, functional, radiological, and socioeconomic outcomes of calcaneus fractures treated with open reduction-internal fixation (ORIF) versus minimally invasive percutaneous fixation (MIPF).

Patients And Methods: A total of 48 patients (34 males, 14 females; mean age: 44.05 years; range, 19 to 64 years) who underwent either ORIF or MIPF for calcaneus fractures between January 2010 and January 2016 were retrospectively analyzed. Read More

Jt Dis Relat Surg 2021 11;32(2):420-427. Epub 2021 Jun 11.

Ankara Şehir Hastanesi Ortopedi ve Travmatoloji Kliniği, El ve Üst Ekstremite Cerrahisi Bölümü, 06800 Çankaya, Ankara, Türkiye.

Objectives: Calcaneal fractures are the most common tarsal fractures following a foot-ankle trauma. The Böhler's angle is an important measurable angle before, during, and after surgery. In this study, we aimed to investigate correlation between Böhler's angle, calcaneal strength, and subtalar joint stress using a finite element analysis (FEA). Read More

Jt Dis Relat Surg 2021 11;32(2):355-362. Epub 2021 Jun 11.

Sağlık Bilimleri Üniversitesi, Antalya Eğitim ve Araştırma Hastanesi Ortopedi ve Travmatoloji Kliniği, 07100 Muratpaşa, Antalya, Türkiye.

Objectives: The aim of this study was to investigate the effect of cartilage thickness mismatch on tibiotalar articular contact pressure in osteochondral grafting from femoral condyles to medial talar dome using a finite element analysis (FEA).

Materials And Methods: Flush-implanted osteochondral grafting was performed on the talar centromedial aspect of the dome using osteochondral plugs with two different cartilage thicknesses. One of the plugs had an equal cartilage thickness with the recipient talar cartilage and the second plug had a thicker cartilage representing a plug harvested from the knee. Read More

Prenat Diagn 2021 Jun 18. Epub 2021 Jun 18.

Department of Obstetrics and Gynecology, Texas Children's Hospital & Baylor College of Medicine, Houston, Texas, USA.

Objective: To determine the impact of the lesion type (cystic [myelomeningocele] or flat [myeloschisis]) on the fetal motor function (MF) in cases candidates for prenatal open neural tube defect (ONTD) repair.

Methods: Retrospective cohort study of patients with ONTD who underwent prenatal repair at a single institution between 2011-2019. The lesion type and the measurements of the length and width of the lesions to calculate the surface of the ellipsoid lesion were performed using MR scans. Read More

Arch Orthop Trauma Surg 2021 Jun 19. Epub 2021 Jun 19.

Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.

Introduction: We have experienced unexpected under-correction after medial opening wedge high tibial osteotomy (MOWHTO). Although the tibia was corrected accurately, the postoperative mechanical axis (MA) was less than 57%. The purpose of this study was to evaluate the relationship between hindfoot alignment and postoperative lower limb alignment, and to reveal whether hindfoot alignment affects lower limb alignment after MOWHTO. Read More

BMC Musculoskelet Disord 2021 Jun 18;22(1):558. Epub 2021 Jun 18.

Division of Orthopaedic Surgery, Dalhousie University, Queen Elizabeth II Health Sciences Center Halifax Infirmary (Suite 4867), 1796 Summer Street, Halifax, NS, B3H3A7, Canada.

Background: Inversion ankle sprains, or lateral ankle sprains, often result in symptomatic lateral ankle instability, and some patients need lateral ankle ligament reconstruction to reduce pain, improve function, and prevent subsequent injuries. Although anatomically reconstructed ligaments should behave in a biomechanically normal manner, previous studies have not measured the strain patterns of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) after anatomical reconstruction. This study aimed to measure the strain patterns of normal and reconstructed ATFL and CFLs using the miniaturization ligament performance probe (MLPP) system. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Background: Many people experience gastrocnemius tightness. Few studies demonstrate the relationship between gastrocnemius tightness and forefoot pathology. This study aimed to define the association between intractable plantar keratosis of the second rocker (IPK2) (also known as well-localized IPK or discrete keratosis) and metatarsalgia. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Tenosynovial giant cell tumor is the common term used to describe a group of soft-tissue tumors that share a common etiologic link. These tumors are relatively infrequent in the foot and ankle, and occasionally they may be the cause of destruction of the adjacent bone structures. We report the imaging appearance and pathologic findings of two patients with localized tenosynovial giant cell tumor of the forefoot. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Background: No detailed comparative studies have been performed regarding plantar pressure changes between proximal dome and distal chevron osteotomies. This study aimed to compare radiographic and plantar pressure changes after distal chevron and proximal dome osteotomies and to investigate the effect of radiographic and plantar pressure changes on clinical outcomes.

Methods: This study included 26 and 22 patients who underwent distal chevron and proximal dome osteotomies, respectively. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Tenosynovial giant cell tumor, also known as giant cell tumor of the tendon sheath (GCT-TS), is a solitary, nodular, firm, benign, soft-tissue tumor that arises from the synovial lining of a tendon. The etiology is unknown. It is a rare soft-tissue tumor, with an overall incidence of one in 50,000 individuals, and usually affects people aged between 30 and 50 years. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Osteomyelitis of the calcaneus combined with a pathologic fracture is a rare and difficult presentation for any practicing foot and ankle surgeon. Treatment for achieving an aseptic nonunion involves a variety of steps, including surgical debridement, antibiotic administration, and fracture stabilization. In this case series, we report a novel technique for the treatment of a tongue-type calcaneal fracture in the setting of chronic osteomyelitis using the Biomet JuggerLoc bone-to-bone system for fixation. Read More

J Am Podiatr Med Assoc 2021 May;111(3)

Background: The objective of this investigation was to determine the level of agreement between a systematic clinical Doppler examination of the foot and ankle and diagnostic peripheral angiography.

Methods: The described Doppler examination technique attempted to determine the patency, quality, and direction of the flow through the dorsalis pedis artery, posterior tibial artery, terminal branches of the peroneal artery, and vascular arch of the foot. These results were then compared with angiographic distal run-off images as interpreted by a blinded vascular surgeon. Read More

Phys Ther Sport 2021 Jun 9;51:1-7. Epub 2021 Jun 9.

Centre for Injury Prevention and Performance, Athletic Therapy and Training, School of Health and Human Performance, Dublin City University, Dublin 9, Ireland.

Objective: To understand the incidence and burden of injury of student-athletes in four of the most popular collegiate sports.

Design: Prospective cohort study.

Setting: Collegiate sport. Read More