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Clin Imaging 2021 Apr 14;76:228-234. Epub 2021 Apr 14.

Ankara University, School of Medicine, Department of Biostatistics, Talatpaşa Bulvarı, Sıhhiye, 06100 Ankara, Turkey.

Purpose: To evaluate the association of visceral adiposity measured on computed tomography (CT) in preoperative period with lymph node (LN) metastasis and overall survival in gastric adenocarcinoma patients.

Methods: Preoperative CT scans of 246 gastric adenocarcinoma patients who did not receive neoadjuvant chemoradiotherapy were evaluated. Visceral fat area (VFA), subcutaneous fat area (SFA) and Total fat area (TFA), VFA/TFA ratio were quantified by CT. Read More

Autoimmun Rev 2021 May 7:102841. Epub 2021 May 7.

Department of Pediatric Intensive Care, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Heart Rhythm 2021 May 7. Epub 2021 May 7.

Division of Cardiology, Department of Medicine, Columbia University College of Physicians and Surgeon, 630 W 168th St, New York, NY, 10032, USA.

Background: Coronary sinus (CS) ostial atresia/anomalies prevents access to the CS from the right atrium (RA) for left ventricular (LV) lead implantation. Some patients with CS ostial anomalies also have a small persistent left superior vena cava (sPLSVC).

Objective: Describe CS ostial anomalies and sPLSVC as an opportunity for LV lead implantation and unrecognized source of stroke. Read More

Infect Genet Evol 2021 May 7:104907. Epub 2021 May 7.

Ankara University Faculty of Veterinary Medicine, Department of Parasitology, Ankara, Turkey.

Purpose: Today, almost 15 years have passed since the whole genome sequence (WGS) of a Leishmania parasite was completed for the first time. However, information on the genetics of these parasites remains to be elucidated. Genome-based studies may contribute to control strategies for leishmaniasis. Read More

Urology 2021 May 7. Epub 2021 May 7.

Ankara University Faculty of Medicine, UROLOGY Department. Electronic address:

Objective: To compare the 2012 American Urological Association (AUA) and 2020 AUA/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) microscopic hematuria (MH) guidelines as applied in 1,018 patients with MH, to confirm of risk groups and to investigate the natural history of patients with MH.

Materials And Methods: Patients who had undergone a complete urological evaluation for MH according to the 2012 AUA MH guidelines were identified retrospectively. All the patients were then classified into low-, intermediate-, or high-risk for urinary tract malignancy according to the updated 2020 AUA/SUFU MH guidelines, for a second evaluation. Read More

Microcirculation 2021 May 10:e12704. Epub 2021 May 10.

Department of Cardiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.

Objective: To determine the possible alterations of retinal microcirculation associated with right-sided intracardiac pressures in patients with IPAH METHODS: Twenty patients with IPAH and 20 age- and sex-matched healthy controls were included in the study. Hemodynamic data were obtained from the most recent right heart catheterization. Echocardiographic examination was performed within 24 hours of ophthalmological examination. Read More

Logoped Phoniatr Vocol 2021 May 10:1-7. Epub 2021 May 10.

Department of Otolaryngology, Gazi University, Ankara, Turkey.

Background: As the duration of diabetes progresses, various disease related complications might occur in patients. The main goal of this paper is to compare acoustic and aerodynamic measures of patients with type 2 diabetes mellitus (T2DM) with a control group of healthy subjects.

Methods: A total of 91 subjects, 51 individuals with type 2 diabetes mellitus (DM group) and 40 healthy volunteers (HV group) were participated in the study. Read More

Public Health Pract (Oxf) 2021 Nov 10;2:100064. Epub 2020 Dec 10.

Division of Biostatistics and Data Science, Department of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Objectives: The COVID-19 pandemic caused by the novel SARS-CoV-2 coronavirus has drastically altered the global realities. Harnessing national scale data from the COVID-19 pandemic may better inform policy makers in decision making surrounding the reopening of society. We examined country-level, daily-confirmed, COVID-19 case data from the World Health Organization (WHO) to better understand the comparative dynamics associated with the ongoing global pandemic at a national scale. Read More

Turk J Emerg Med 2021 Apr-Jun;21(2):69-74. Epub 2021 Feb 12.

Department of Emergency Medicine, Emergency Service, Sincan State Hospital, Ankara, Turkey.

Objectives: Although studies in the field of emergency medical services (EMS) generally compare survival and hospital discharge rates, there are not many studies measuring the quality of cardiopulmonary resuscitation (CPR). In this study, we aimed to compare the mechanical chest compression device and paramedics in terms of CPR quality.

Methods: This is an experimental trial. Read More

Turk J Emerg Med 2021 Apr-Jun;21(2):51-55. Epub 2021 Feb 12.

Department of Emergency, Gazi University School of Medicine, Ankara, Turkey.

Objective: Whether the use of metronome affects the quality of cardiopulmonary resuscitation (CPR) remains unclear. In this study, we investigated the effect of metronome use on CPR quality.

Methods: This was a prospective, simulation-based CPR manikin study. Read More

Cureus 2021 Apr 6;13(4):e14319. Epub 2021 Apr 6.

Department of Obstetrics and Gynecology, Gazi University, School of Medicine, Ankara, TUR.

Objectives This study aimed to compare the presence of blepharitis, ocular tension (OT) with corneal thickness, refractive values and ocular axial length changes in premenopausal and postmenopausal women. Materials and methods Thyroid-stimulating hormone (TSH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), oestradiol (E2), refractive values with prolactin, refractions in horizontal and vertical meridians, OT values, ocular axial length, central corneal thickness and the presence of blepharitis were evaluated in 153 premenopausal patients and 142 postmenopausal patients. Results Statistically significant differences were found for the values for right eye OT (P < 0. Read More

Curr Psychol 2021 Apr 30:1-13. Epub 2021 Apr 30.

Hacettepe University, Ankara, Turkey.

The coronavirus pandemic has caused unemployment to skyrocket, exposed the longstanding inequalities in health care services and working conditions, and mainly affected the poor in different parts of the world. In the current study, we focus on social identity and social class-related factors that are critical during the pandemic to gain insights into what predicts support for policies favoring economic equality in the post-pandemic period. We argue that to the extent that individuals 1) identify with all humanity during the pandemic, 2) are aware of their socio-economic status-based privilege, 3) do not hold classist attitudes, they would support policies favoring economic equality. Read More

J Food Sci Technol 2021 Jun 24;58(6):2121-2132. Epub 2020 Aug 24.

Faculty of Engineering, Chemical Engineering Department, Ankara University, Dögol Street 06100 10th Year Campus, Beşevler/Ankara, Turkey.

Grapes are known to synthesize resveratrol, a stilbene phytoalexin, associated with cancer chemopreventive activity and cardioprotection. The effect of ultrasound (US) abiotic elicitor treatments on trans-resveratrol content in Kalecik Karası fresh and frozen grape skin was determined. D-optimal point change design was used under RSM for the experimental design of US treatment. Read More

Wilderness Environ Med 2021 May 6. Epub 2021 May 6.

Division of Pediatric Critical Care Medicine, Ankara University Faculty of Medicine, Ankara, Turkey.

Carbohydr Polym 2021 Aug 12;265:118066. Epub 2021 Apr 12.

Department of Biotechnology, Middle East Technical University, Ankara, 06800, Turkey; Department of Engineering Sciences, Middle East Technical University, Ankara, 06800, Turkey; BIOMATEN Center of Excellence in Biomaterials and Tissue Engineering, Middle East Technical University, Ankara, 06800, Turkey. Electronic address:

This study aims to develop a novel intraperitoneal two- or three-layered patch with immunomodulatory property for treatment of hernia, regeneration of abdominal wall and prevention of intraperitoneal adhesions. Polypropylene (PP) mesh, middle layer, was intended to provide mechanical support whereas pullulan (PUL) hydrogel coating layer was designed to prevent intraperitoneal adhesions. Fibroin/chitosan oligosaccharide lactate (F/COS) layer electrospun on one side of pullulan was chosen for immunomodulation and abdominal wall regeneration. Read More

Taiwan J Obstet Gynecol 2021 May;60(3):487-491

Kutahya Health Sciences University, School of Medicine, Department of Obstetrics and Gynecology, Kutahya, Turkey.

Objectives: Women with polycystic ovary syndrome (PCOS) have an increased cardiometabolic risk. Similarly, it was previously shown that atherosclerotic and cardiovascular risk is increased in the general population with lower serum Klotho levels. The aim of this study was to investigate the lotho and thiol/disulfide levels in women with non-obese PCOS compared to healthy controls and also to investigate the relationship of serum Klotho and thiol/disulfide homeostasis with cardiometabolic risk factors. Read More

Reprod Sci 2021 May 8. Epub 2021 May 8.

Laboratory Animal Care and Research Unit, Department of Pharmacology, Faculty of Pharmacy, Gazi University, Etiler, 06330, Ankara, Turkey.

Endometritis is characterized by inflammation of the endometrial lining that leads to reduced reproductive potential. Restoring the impaired hormonal balance is an important component of endometritis treatment. The purpose of the current study was to evaluate the effects of resveratrol on estrogen and progesterone hormone status in endometritis. Read More

Exp Gerontol 2021 May 6;150:111384. Epub 2021 May 6.

Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Turkey.

Introduction: Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by the death of dopaminergic neurons in the substantia nigra pars compacta. Exercise training, which is incorporated both goal-based training such as task-oriented training (TOT) and aerobic training (AT), has been suggested to induce neuroprotection. However, molecular mechanisms which may underlie exercise-induced neuroprotection are still largely unknown. Read More

Cardiovasc Revasc Med 2021 May 5. Epub 2021 May 5.

Gazi University, Faculty of Medicine, Department of Orthopedics and Traumatology, Ankara, Turkey.

Mater Sci Eng C Mater Biol Appl 2021 Jun 1;125:112092. Epub 2021 Apr 1.

Hacettepe University, Bioengineering Department, 06800 Beytepe, Ankara, Turkey; Hacettepe University, Chemical Engineering Department, 06800 Beytepe, Ankara, Turkey. Electronic address:

In osteochondral tissue engineering, while the biochemical and mechanical properties of hydrogels guide stem cell proliferation and differentiation, physical and chemical stimulators also affect the differentiation of stem cells. Herein, we presented a patient and tissue-specific strategy for the development of biomimetic osteochondral constructs with gradient compositions. Osteochondral constructs were fabricated by gradually printing of bio-inks consisting of therapeutic platelet-rich plasma (PRP), adipose tissue-derived mesenchymal stem cells (AdMSCs), and extracellular matrix (ECM) mimetic hydrogel, microwave-assisted methacrylated gelatin (Gel-MA). Read More

Int J Clin Pract 2021 May 9:e14339. Epub 2021 May 9.

Department of Pediatric Urology, Gazi University School of Medicine, Ankara.

Purpose: We designed a multicenter, retrospective study to investigate the current trends in initial management of reflux with respect to European Association of Urology (EAU) Guidelines in Urology clinics of our country.

Materials And Methods: The study group consisted of 1988 renal units (RU) of 1345 patients treated surgically due to vesicoureteral reflux (VUR) (between years 2003-2017 in 9 different institutions. Patients were divided into 2 groups according to time of initial treatment and also grouped according to risk factors by "EAU guidelines on VUR". Read More

Psychiatry Res 2021 Apr 29;301:113976. Epub 2021 Apr 29.

Department of Psychiatry, Gülhane Training and Research Hospital, Ankara, Turkey.

Backgrounds: Although the psychological effects of the COVID-19 pandemic have been investigated, there is no study comparing the effects between the peaks. This study aims to compare the levels of anxiety, depression, and stress of healthcare workers struggling with pandemic between the first and second peaks.

Methods: A total of 2460 healthcare workers, 1051 from the first peak period and 1409 from the second peak period, were included in the study. Read More

Neuromuscul Disord 2021 Apr 9. Epub 2021 Apr 9.

Department of Pediatrics, Pediatric Metabolism and Nutrition Unit, Hacettepe University Faculty of Medicine, Ankara 06230, Turkey. Electronic address:

Very long-chain acyl-coenzyme A (CoA) dehydrogenase (VLCAD) deficiency is an autosomal recessive fatty acid oxidation disorder characterized by rhabdomyolysis, hypoglycemia and cardiomyopathy. The general treatment approach in adult patients is based on the prevention of catabolism. High carbohydrate, low fat diet and supplementation of medium-chain triglycerides are essential in the treatment. Read More

Turk J Med Sci 2021 May 9. Epub 2021 May 9.

Background/aim: Obesity is one of the main public health issue in many countries including Turkey. The aim of the study is to test cross-cultural adaptation, reliability, and validity of QOLOD rating scale in Turkish Language.

Materials And Methods: This methodological study was conducted among the overweight and obesity people between February ? March, 2018 in Ankara Atatürk Training and Research Hospital. Read More

Arch Oral Biol 2021 Apr 30;127:105139. Epub 2021 Apr 30.

Ankara University, Faculty of Medicine, Department of Medical Biochemistry, Ankara, Turkey.

Objective: Hypericum perforatum L also known as St. John's wort is known to have many beneficial properties for the organism including its antioxidant and anticancer activities. It is also known to have shown antiproliferative and cytotoxic effects against various cancer cell lines. Read More

Mycoses 2021 May 8. Epub 2021 May 8.

Department of Dermatology, Guglielmo Marconi University, Rome, Italy.

Objectives: Onychomycosis is the general term to define fungal nail infections that arise from dermatophytes, non-dermatophytic molds, and yeasts. Thiol/disulfide homeostasis is a new indicator of oxidative stress. In this study, we aimed to investigate the role of thiol/disulfide balance in the pathogenesis of onychomycosis. Read More

Eur J Cardiothorac Surg 2021 May 8. Epub 2021 May 8.

Department of Cardiology, Unit of Heart Failure, Heart Transplantation and Mechanical Circulatory Support, Erasmus University Medical Center, Rotterdam, Netherlands.

Objectives: Driveline infections continue to be a significant complication following left ventricular assist device (LVAD) implantation. Driveline exit-site care is crucial for the prevention of infections; however, there are no uniform guidelines. The goal of this study was to provide an overview of the currently published driveline exit-site care protocols in patients with LVAD. Read More

Ann Hum Genet 2021 May 8. Epub 2021 May 8.

Department of Medical Genetics, University of Health Sciences, Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey.

Hereditary myopathies are a heterogeneous disorder known to be associated with more than 100 genes. Although hereditary myopathy subgroups can be partially described with traditional methods such as muscle biopsy, next-generation sequencing (NGS) is essential to reveal the disease's underlying genetic etiology and molecular mechanisms. In this study, we performed clinical exome sequencing or whole-exome sequencing (CES/WES) in 20 unrelated Turkish patients. Read More

Endocrine 2021 May 8. Epub 2021 May 8.

Institute of Endocrine and Metabolic Sciences, Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milano, Italy.

Background: COVID-19 has completely changed our daily clinical practice as well as our social relations. Many organs and biological systems are involved in SARS-Cov-2 infection, either due to direct virus-induced damage or to indirect effects that can have systemic consequences. Endocrine system is not only an exception but its involvement in COVID-19 is so relevant that an "endocrine phenotype" of COVID-19 has progressively acquired clinical relevance. Read More