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J Clin Virol 2022 May 14;152:105184. Epub 2022 May 14.

Laboratoire de Virologie, Institut des Agents Infectieux (IAI), Hospices Civils de Lyon, 103 Grande Rue de la Croix-Rousse, Lyon 69317 CEDEX 04, France; Centre National de Référence des virus des infections respiratoires dont la grippe, Lyon, France. Electronic address:

Background: The Global Influenza Hospital Surveillance Network (GIHSN) has operated with the aim of investigating epidemiological and clinical factors related to severe influenza-related hospitalisations.

Study Design: A common GIHSN core protocol for prospective patient enrolment was implemented. Hospital personnel completed a standardized questionnaire regarding the included patients' medical history, compiled a hospitalisation summary, collected an upper respiratory swab sample for laboratory diagnosis, and genome sequencing was performed for a subset of samples. Read More

Seizure 2022 May 10;99:48-53. Epub 2022 May 10.

Department of Pediatric Neurology, Istanbul Medipol University Faculty of Medicine, Istanbul, Turkey.

Purpose: Valproic acid (VPA) is frequently used and effective in juvenile myoclonic epilepsy (JME). Recently, levetiracetam (LEV) has been suggested as a monotherapy in JME. This study aimed to evaluate antiseizure medication (ASM) use in patients with JME. Read More

Tech Coloproctol 2022 May 20. Epub 2022 May 20.

Department of General Surgery and Anatomy, Faculty of Medicine, Ankara University, Sıhhıye, 06100, Ankara, Turkey.

Background: Pelvic surgery carries an inherent risk of autonomic nerve injury leading to genitourinary and bowel dysfunction due to the close proximity of the superior hypogastric plexus (SHP). The aim of this study was to define the detailed anatomy of SHP and identify its relationship with the vascular landmarks and ureters for pelvic autonomic nerve-preserving surgery.

Methods: A cadaveric study on the detailed anatomy of the SHP was conducted in our surgical anatomy research unit. Read More

Int J Nurs Knowl 2022 May 20. Epub 2022 May 20.

Proffesor, Dr., Gazi University, Faculty of Health Sciences, Department of Nursing, Ankara, Turkey.

Objective: This research aims to investigate the effects of web-based mind map learning techniques in the nursing process on students' ability to investigate the nursing diagnosis, descriptive characteristics, and the etiological and risk factors.

Design: In this experimental study, 91 nursing students enrolled in a state university in a city in Turkey in the 2020-2021 academic year were included.

Methods: Data were collected using a test for determining the level of knowledge about the nursing diagnosis and the factors affecting the diagnosis, case sample, and care plan. Read More

Niger J Clin Pract 2022 May;25(5):683-689

Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Ankara, Turkey.

Background And Aim: Nasotracheal intubation is the main route to secure the airway in oral and maxillofacial surgery patients. This study was aimed to compare the intubation times and glottis visualization of McGrath video laryngoscope with the Macintosh laryngoscope for routine nasotracheal intubation.

Materials And Methods: Records of seventy-one ASA (American Society of Anesthesiologists) I-II patients were evaluated and allocated into two groups (McGrath video laryngoscope (VL) and Macintosh groups). Read More

Niger J Clin Pract 2022 May;25(5):677-682

Izmir Demokrasi University, Vocational School of Health Services, İzmir, Turkey.

Background: Peer-assisted education (PAE) is a collaborative and active learning strategy in which another student or another student group teaches one group of students. This model is quite widely used in social and health science vocational education.

Aim: This study was carried out to determine the effect of peer education on clinical skill learning and anxiety in nursing students. Read More

Niger J Clin Pract 2022 May;25(5):670-676

Department of Endodontics, Faculty of Dentistry, Necmettin Erbakan University, Konya, Turkey.

Background: Irrigant activation techniques, which are more effective in anatomically complex areas, can be used to maximize irrigant efficacy.

Aim: This in vitro study aimed to evaluate the efficacy of different agitation techniques on the dislocation resistance of Biodentine to the root canal dentin.

Materials And Methods: Seventy single-rooted teeth divided into seven experimental groups (n = 10); Group I-Irritrol/Photon-induced-photoacoustic-streaming (PIPS), Group II-Irritrol/EDDY, Group III- Irritrol/Syringe-needle-irrigation (SNI), Group IV-Chlorhexidine-gluconate (CHX)/PIPS, Group V-CHX/EDDY, Group VI-CHX/SNI, Group VII-Saline. Read More

Niger J Clin Pract 2022 May;25(5):647-652

Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Çankaya, Ankara, Turkey.

Background And Aim: Selecting the optimum nasal passage for nasotracheal intubation is quite important in the maxillofacial surgeries for the success of intubation and the reduction of potential complications such as nasal mucosal laceration, epistaxis, avulsion of the inferior and middle turbinates, and septal laceration.

Materials And Methods: The present study evaluates standard panoramic radiographs (PR) and posteroanterior cephalometric radiographs (PACR) to determine the optimal nasal passage for nasotracheal intubation and compares the results with those of routine anesthesiological occlusion and spatula tests (ST). The results of occlusion tests (OT), ST, and radiological assessments of 60 patients prior to nasotracheal intubation were compared with the nasal endoscopic assessment results, and complications were evaluated. Read More

Niger J Clin Pract 2022 May;25(5):636-640

Department of Emergency Medicine, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.

Background And Aim: Primary dysmenorrhea (PD) is a common presentation for emergency departments. This study investigates the diagnostic value of oxidative stress and ischemia markers in patients with PD.

Materials And Methods: The participants were classified into the PD group (patients with PD) and the control group (healthy volunteers). Read More

Niger J Clin Pract 2022 May;25(5):621-629

Department of Oral and Maxillofacial Surgery, Van Yuzuncu Yil University Faculty of Dentistry, Van, Turkey.

Background: The COVID-19 pandemic has caused not only viral infection-related deaths, but also uncontrollable psychological problems and anxiety in different parts of society. The COVID-19 pandemic has resulted in adaption of a comprehensive online education period that has not been previously experienced in modern education.

Aim: This cross-sectional study aims to evaluate dental students' experiences with emergency remote education practices, related levels of anxiety, and sociodemographic factors affecting anxiety during the COVID-19 pandemic. Read More

J Cosmet Dermatol 2022 May 20. Epub 2022 May 20.

Department of Dermatology, University Medical Center, Mainz, Germany.

Indian J Dermatol Venereol Leprol 2022 Apr 12:1-3. Epub 2022 Apr 12.

Department of Plastic, Reconstructive and Aesthetic Surgery, Baskent University Faculty of Medicine, Baskent University, Ankara, Turkey.

Psych J 2022 May 20. Epub 2022 May 20.

School of Medicine, Department of Psychiatry, Ankara University, Ankara, Turkey.

It is known that there is an increase in the frequency of psychiatric disturbances in the acute and post-illness phase of coronavirus disease (COVID-19). Comorbid psychiatric symptoms complicate the management of patients and negatively affect the prognosis, but there is no clear evidence of their progress. We aimed to determine psychiatric comorbidity in inpatients and outpatients with COVID-19 and recognize the factors that predict psychiatric comorbidity. Read More

Cureus 2022 Apr 16;14(4):e24175. Epub 2022 Apr 16.

Medical Oncology, Ankara University School of Medicine, Ankara, TUR.

Aim To assess the actionable genomic landscape of colon adenocarcinoma in the primary and metastatic tumor tissues. Methods The data from the American Association for Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) were used in this study. Colon adenocarcinoma patients with primary and metastatic tissue samples (distant organ and lymph node) were selected. Read More

Cureus 2022 Apr 15;14(4):e24158. Epub 2022 Apr 15.

Department of Mechanical Engineering, Union of Chambers and Commodity Exchanges of Turkey (TOBB) University of Economics and Technology, Ankara, TUR.

Objectives Anterior column fractures can be seen as either isolated or accompanied by many types of complex acetabulum fractures. The aim of this study was to biomechanically compare the stability of a standard pelvic brim plate with a more laterally located suprapectineal plate, which is more commonly used in minimally invasive application, on an intermediate height anterior column fracture model under dynamic and static loading. Materials and methods Right side, adult, foam cortical shell artificial hemipelvis models were used (Sawbones, Pacific Research Laboratories, Vashon, WA, USA). Read More

Cureus 2022 Apr 16;14(4):e24192. Epub 2022 Apr 16.

Rheumatology, Akdeniz University, Antalya, TUR.

Introduction Further diagnostic procedures are necessary for patients with fever of unknown origin (FUO) and unknown cause of inflammation (inflammation of unknown origin - IUO) for the identification of the definitive diagnosis. The aim of this study was to evaluate the contribution and roles of F-18 FDG PET/CT (fluoro-18 fluorodeoxyglucose-positron emission tomography/computed tomography) in the diagnostic process of patients with FUO/IUO. Methods The data of 58 patients who had F-18 FDG PET/CT scans for FUO/IUO were re-evaluated retrospectively. Read More

Cureus 2022 Apr 17;14(4):e24201. Epub 2022 Apr 17.

Department of Critical Care Medicine, Health of Science Ankara City Hospital, Ankara, TUR.

Background and aims Pregnant women are one of the vulnerable groups affected by COVID-19. With the mutation of the virus, the severity of the disease in this vulnerable group may vary in different waves of COVID-19 subtypes. The aim of this study is to define the demographic, clinical, laboratory, and mortality results of pregnant COVID-19 patients according to three time frames (March to December 2020, January to June 2021, and July to November 2021). Read More

Arch Med Sci 2022 29;18(3):647-651. Epub 2020 Jan 29.

Department of Obstetrics and Gynecology, Faculty of Medicine, Başkent University, Ankara, Turkey.

Introduction: High estrogen levels could reduce pregnancy rates by disrupting the implantation of the embryo into the endometrium in patients treated with fresh cycles of fertilization. The aim of the present study was to investigate the effect of estrogen levels on the pregnancy and abortion rate in autologous frozen embryo transfer with hormone replacement therapy (HRT).

Material And Methods: A historical cohort study was conducted in an academic setting to investigate the effect of estrogen levels on the pregnancy and abortion rates for all autologous artificial frozen embryo transfer cycles performed from January 2016 to January 2018. Read More

Materials (Basel) 2022 May 9;15(9). Epub 2022 May 9.

Department of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Arcavacata di Rende, 87036 Cosenza, CS, Italy.

A multi-analytical approach was employed to study wall paintings located in the church at Paola, in the province of Cosenza, Italy. The site is an underground church (hence the name of Sotterra, which means "under the earth") rediscovered in the second half of the 19th century, during the building works of the church on the same area. This underground church preserves valuable mural paintings having different styles. Read More

BMC Cardiovasc Disord 2022 May 19;22(1):229. Epub 2022 May 19.

Department of Medical Genetics, Baskent University Faculty of Medicine, Ankara, Turkey.

Background: To evaluate the relationship between IL-1α -889C/T (rs1800587), IL-1β -511C > T (rs16944), TNFα -308G > A (rs1800629), TNFα -238G > A (rs361525), IL-6 -174G > C (rs1800795), and IL-6 -572G > C (rs1800796) polymorphisms and the susceptibility to transposition of the great arteries (TGA).

Methods: A prospective analysis was performed on mothers whose newborns were diagnosed as having TGA. For each case of TGA, a mother who gave birth to a healthy neonate in the same period was randomly selected for the control group. Read More

Pediatr Allergy Immunol Pulmonol 2022 May 18. Epub 2022 May 18.

Department of Pediatric Allergy and Immunology, University of Health Sciences, Ankara Children's Hospital, Ankara City Hospital, Ankara, Turkey.

Previous studies reported that the prevalence of drug allergy is higher in patients with cystic fibrosis (CF) than in the general population. It is important to exclude or confirm the drug allergy diagnosis with detailed allergic evaluation for preventing drug allergy overdiagnosis. Our study aims to determine the actual frequency of drug allergy proven by diagnostic tests in children with CF and to compare it with the control group. Read More

Clin Oral Investig 2022 May 19. Epub 2022 May 19.

Department of Periodontology, Faculty of Dentistry, School of Dentistry, Ankara University, 06500, Cankaya, Ankara, Turkey.

Objectives: Kynurenine pathway (KP) is the primary way of degrading tryptophan (TRP) and generates several bioactive metabolites (such as kynurenine (KYN), kynurenic acid (KYNA), 3-hydroxykynurenine (3OHKYN)) to regulate biological processes that include host-microbiome signaling and immune cell response. This study is aimed to determine the relationship between periodontal inflammation and tryptophan-kynurenine metabolism and identify their association with periodontal clinical parameters.

Materials And Methods: Saliva and serum samples were collected from 20 stage III, grade B generalized periodontitis patients, and 20 periodontally healthy control individuals. Read More

Interact Cardiovasc Thorac Surg 2022 May 18. Epub 2022 May 18.

Department of Cardiac Surgery, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, USA.

Biomed Tech (Berl) 2022 May 20. Epub 2022 May 20.

Department of Prosthodontics, Faculty of Dentistry, Istanbul Okan University, Istanbul, Turkey.

The study aimed to evaluate the biomechanical behaviors of different prosthetic materials and posterior implant angles in All-on-4 implant-supported fixed maxillary prostheses with three-dimensional (3D) finite element analysis. The model of complete edentulous maxilla was created using the Rhinoceros and VRMesh Studio programs. Anterior vertical and 17°- and 30°-angled posterior implants were positioned with All-on-4 design. Read More

Brain Connect 2022 May 19. Epub 2022 May 19.

Bilkent Üniversitesi, 52948, Ankara, Ankara, Turkey;

Introduction: The role of the cerebellum in motor function is well recognized. However, its role in higher nervous system activities such as cognition, emotion, endocrine, and autonomic are less known. The present study aims to show direct dento-amygdala projections using a biotinylated dextran amine (BDA) tracer in rats and 3-tesla high-resolution diffusion tensor imaging (DTI) based tractography in humans. Read More

Science 2022 May 19:eabm6380. Epub 2022 May 19.

Paris Cité University, Imagine Institute, 75015 Paris, France.

The molecular basis of interindividual clinical variability upon infection with is unclear. We describe patients with haploinsufficiency for the linear deubiquitinase OTULIN, encoded by a gene on chromosome 5p. Patients present episodes of life-threatening necrosis, typically triggered by infection. Read More

Acta Neurol Belg 2022 May 19. Epub 2022 May 19.

Department of Medical Oncology, Hacettepe University Cancer Institute, Ankara, Turkey.

Introduction: Stroke-like migraine attacks after radiation therapy (SMART) syndrome, is a late complication of brain radiotherapy (1). Symptoms are commonly subacute in onset and involve migraine type of headache, seizures, focal neurologic deficits (2). Magnetic resonance imaging (MRI) findings are usually unilateral and posterior predominant cortical-subcortical hyperintensity, swelling and prominent gyriform (cortical and leptomeningeal) gadolinium enhancement in the areas of the brain that underwent irradiation with or without diffusion restriction (1). Read More

Eur Rev Med Pharmacol Sci 2022 May;26(9):3367-3373

Department of Anesthesiology and Reanimation, Infectious Diseases Department, Kecioren Training and Research Hospital, Ankara, Turkey.

Objective: SARS-CoV-2 infection, which causes severe pneumonia, caused an epidemic that started in Wuhan, China in December 2019 and spread to the whole world. COVID-19 mainly affects the respiratory system and causes the development of severe pneumonia and related acute respiratory distress syndrome (ARDS) in some patients. We aimed to investigate whether COVID-19 pneumonia cases can be evaluated in different categories in clinical and radiological terms. Read More

Eur Rev Med Pharmacol Sci 2022 May;26(9):3179-3184

Department of Cardiology, Ankara City Hospital, Ankara, Turkey.

Objective: Diagnostic workup of coronary artery disease (CAD) requires a stepwise approach, starting with detailed history-taking and ending with invasive coronary angiography (ICA) in some cases. The neutrophil to high-density lipoprotein cholesterol (HDL-C) ratio (NHR) is related to CAD. We assessed the association between the NHR and anatomical significance of coronary artery stenosis (CAS) in patients with documented ischemia. Read More

Hum Reprod Update 2022 May 18. Epub 2022 May 18.

Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia.

Background: Intrauterine insemination with ovarian stimulation (IUI-OS) is a first-line treatment for unexplained infertility. Gonadotrophins, letrozole and clomiphene citrate (CC) are commonly used agents during IUI-OS and have been compared in multiple aggregate data meta-analyses, with substantial heterogeneity and no analysis on time-to-event outcomes. Individual participant data meta-analysis (IPD-MA) is considered the gold standard for evidence synthesis as it can offset inadequate reporting of individual studies by obtaining the IPD, and allows analyses on treatment-covariate interactions to identify couples who benefit most from a particular treatment. Read More