1,058 results match your criteria Anisocoria

Pharmacologic Mydriasis Secondary to Topical Glycopyrronium Tosylate Cloths: Clinical Characterization From a Multicenter Analysis.

J Neuroophthalmol 2022 Mar 24. Epub 2022 Mar 24.

Department of Ophthalmology and Visual Sciences (ARK, SG, PWM, BTJ, KMC), Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois; NorthShore University Health System (JHP), Evanston, Illinois; Department of Ophthalmology (TMJ, NRC), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Neurology (NRC), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Des Peres Eye Center (EC), Des Peres, Missouri; Department of Ophthalmology (EAS), Rush University Medical Center, Chicago, Illinois; Department of Ophthalmology (KCG), University of Cincinnati College of Medicine (KCG), Cincinnati, Ohio; Cincinnati Eye Institute (KCG), Cincinnati, Ohio; and Midwest Retina Consultants (EG-V), Arlington Heights, Illinois.

Background: Topical glycopyrronium tosylate (GT) is an anticholinergic medication for treatment of axillary hyperhidrosis. Pharmacologic mydriasis and anisocoria from topical GT has been reported and may be underrecognized. This study aims to clinically characterize patients presenting with pharmacologic mydriasis from exposure to this medication. Read More

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Anisocoria Due to Ocular Ischemic Syndrome.

J Neuroophthalmol 2022 Mar 24. Epub 2022 Mar 24.

Department of Ophthalmology (ATL, JAD, CEF), University of Washington, Seattle, Washington; and Department of Neurological Surgery (CEF), University of Washington, Seattle, Washington.

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The role of the craniotomy size in the surgical evacuation of acute subdural hematomas in elderly patients: a retrospective multicentric study.

J Neurosurg Sci 2022 Apr 5. Epub 2022 Apr 5.

Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy -

Background: Elderly patients operated for an acute subdural hematoma (ASDH) frequently have a poor outcome, with a high frequency of death, vegetative status, or severe disability (Glasgow Outcome Score, GOS, 1-3). Minicraniotomy has been proposed as a minimally invasive surgical treatment to reduce the impact of surgery in the elderly population. The present study aimed to compare the influence of the size of the craniotomy on the functional outcome in patients undergoing surgical treatment for ASDH. Read More

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Muscular and collagenous cerebellar choristoma in a dog.

J Vet Sci 2022 Mar;23(2):e30

Departamento de Clínica de Pequenos Animais, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil.

This report aims to describe the first case of muscular and collagenous choristoma in a dog. A 10-yr-old female mixed-breed dog presented with lateral recumbence, vocalization, positional vertical nystagmus, divergent strabismus, anisocoria, and status epilepticus. The clinical condition evolved to stupor and ultimately, death. Read More

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Rare causes of anisocoria: Ipratropium bromide and Angel's trumpet.

North Clin Istanb 2021 15;8(6):623-625. Epub 2021 Nov 15.

Department of Pediatrics, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.

It is considered a neurological emergency when a patient presents with anisocoria. It is important that the anisocoria whether or not accompanied by the neurological findings. Other reasons of anisocoria should be considered when the absence of neurological or ophthalmological signs such as change of mental status, hemiparesis, ophthalmoplegia, ptosis. Read More

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November 2021

Characteristics of Patients with Trephine Syndrome: A Retrospective Study.

Prog Rehabil Med 2022 23;7:20220008. Epub 2022 Feb 23.

Department of Rehabilitation Medicine, Kawasaki Medical School, Okayama, Japan.

Objectives: This study retrospectively investigated the prevalence and clinical features of trephine syndrome, which is a late complication of craniectom, in patients who underwent craniectomy decompression.

Methods: Trephine syndrome was defined as an increase of ≥2 points in the functional independent measure (FIM) score at 7 days after cranioplasty compared with that 3 days before cranioplasty. Patients who underwent craniectomy at Kawasaki Medical School Hospital between January 1, 2010, and March 15, 2020, were included in the study. Read More

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February 2022

13q32.1 as a candidate region for physiological anisocoria.

Br J Ophthalmol 2022 Mar 10. Epub 2022 Mar 10.

Department of Psychology, University of Cambridge, Cambridge, UK.

Background: Physiological anisocoria is an asymmetry of pupil size in the absence of pathology.

Methods: Images of the pupils under standard illumination were collected in the course of a whole-genome association study of a range of visual functions in 1060 healthy adults. DNA for each participant was extracted from saliva samples. Read More

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REBOA as a bridge to brain CT in a patient with concomitant brain herniation and haemorrhagic shock - A case report.

Trauma Case Rep 2022 Apr 22;38:100623. Epub 2022 Feb 22.

Anesthesia and Intensive Care Unit, AUSL Romagna - Bufalini Hospital, Cesena, FC, Italy.

Introduction: The management of complex trauma patient with concomitant brain injury and extra-cranial lesions is challenging since the requirement of a low pressure to limit the bleeding clashes with the need to maintain an adequate cerebral perfusion and to obtain a brain CT-scan.Here we present the use of REBOA as a bridge to CT scan in complex head and torso trauma.

Case Presentation: A 59 years old male patient involved in a road traffic crash was admitted to our hospital after a car accident. Read More

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Risk Factors and Outcomes of Redo Craniotomy: A Tertiary Care Center Analysis.

Cureus 2022 Jan 20;14(1):e21440. Epub 2022 Jan 20.

Department of Surgery, Aga Khan University Hospital, Karachi, PAK.

Background and aim Reoperation rate is defined as the percentage of patients returning to the operating room (OR) within 30 days of an initial craniotomy and undergoing a repeat (redo) craniotomy procedure. It is a key factor of quality-of-care assessments and has implications for outcomes, especially in oncological cases. Redo craniotomies are associated with improvement in neurological status and decreased mortality rate compared to non-surgical interventions but are associated with higher costs and risk of complications. Read More

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January 2022

Atypical Presentation of Enlarged Vestibular Aqueducts Caused by Variants.

Children (Basel) 2022 Jan 28;9(2). Epub 2022 Jan 28.

Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu 41944, Korea.

Enlarged vestibular aqueduct is the most common inner ear malformation in pediatric patients with sensorineural hearing loss. Here, we report a new presentation of enlarged vestibular aqueduct in a Korean family. The family consists of two parents and five daughters, and the first and second daughters were diagnosed with bilateral enlarged vestibular aqueducts. Read More

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January 2022

Pilot Study of Smartphone Infrared Pupillography and Pupillometry.

Clin Ophthalmol 2022 8;16:303-310. Epub 2022 Feb 8.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Purpose: To describe and validate a novel portable smartphone-based infrared pupillographer.

Materials And Methods: A prototype infrared smartphone pupillographer device was custom designed for this project. Infrared video and photo pupillography were attempted on 12 patients with different clinical pupillary examination findings. Read More

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February 2022

Contralateral epidural hematoma after decompressive surgery: Case report and systematic literature review.

Ann Med Surg (Lond) 2022 Feb 25;74:103233. Epub 2022 Jan 25.

Neurosurgery Department, University Hospital Center IBN ROCHD, Casablanca, Morocco.

Introduction: and importance: Contralateral epidural hematoma (EDH) after decompressive surgery for acute subdural hematoma (ASDH) is uncommon. If unrecognized, this delayed hematoma can lead to devastating consequences.

Case Presentation: A 30-year-old patient with no past medical history, was brought to the emergency after a severe brain injury secondary to an aggression, Glasgow coma scale was 6 (E1V1 M4) with a left anisocoria. Read More

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February 2022

Chewing and Cognitive Improvement: The Side Matters.

Front Syst Neurosci 2021 23;15:749444. Epub 2021 Dec 23.

Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy.

Chewing improves cognitive performance, which is impaired in subjects showing an asymmetry in electromyographic (EMG) masseter activity during clenching. In these subjects, the simultaneous presence of an asymmetry in pupil size (anisocoria) at rest indicates an imbalance in Ascending Reticular Activating System (ARAS) influencing arousal and pupil size. The aim of the present study was to verify whether a trigeminal EMG asymmetry may bias the stimulating effect of chewing on cognition. Read More

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December 2021

Bilateral Adie's Pupil following Laser Treatment of the Ischemic Peripheral Retina for Uveitis: A Case Report.

Case Rep Ophthalmol 2021 Sep-Dec;12(3):909-914. Epub 2021 Nov 11.

Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan.

Adie's pupil is a neurological condition of unknown origin with unusual, asymmetric presentation known as anisocoria with the enlarged pupil failing to react to light. It is believed that this pupillary abnormality results from damage to the ciliary ganglion or postganglionic short ciliary nerves. Affected individuals (usually female) may be symptomatic with photophobia or difficulty reading in the diseased eye. Read More

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November 2021

Anisocoria as a side effect of paclitaxel treatment.

Klin Onkol 2021 ;34(4):306-308

Background: Paclitaxel is one of the most common cytostatics used in oncology; it is part of the therapeutic protocols of many malignancies. One of its most common side effects is peripheral neuropathy. This symptomatology often leads to a reduction in the dose intensity of chemotherapeutic drugs or to early discontinuation of the treatment. Read More

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February 2022

Cranial nerve injuries in patients with moderate to severe head trauma - Analysis of 91,196 patients from the TraumaRegister DGU® between 2008 and 2017.

Clin Neurol Neurosurg 2022 01 8;212:107089. Epub 2021 Dec 8.

University of Witten/Herdecke, Institute for Research in Operative Medicine, Cologne, Germany.

Objective: Traumatic brain injury (TBI) constitutes a major cause of trauma-related disability and mortality. The epidemiology and implications of associated cranial nerve injuries (CNI) in moderate to severe TBI are largely unknown. We aimed to determine the incidence of CNI in a large European cohort of TBI patients as well as clinical differences between TBI cases with and without concomitant CNI (CNI vs. Read More

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January 2022

Unilateral dilated pupil following nasotracheal intubation.

Anaesth Rep 2021 Jul-Dec;9(2):e12142. Epub 2021 Nov 29.

Department of Anaesthesiology Alfred Hospital Melbourne Victoria Australia.

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November 2021

Intracranial hemorrhage in a patient with severe COVID-19 acute respiratory distress syndrome on Veno-venous extra corporeal membrane oxygenation: A case report.

Ann Med Surg (Lond) 2022 Jan 3;73:103033. Epub 2021 Dec 3.

Department of Critical Care Medicine, AIG Asian Institute of Gasteroenterology Hospitals, Gachibowli, Hyderabad, Telangana, India.

Introduction And Importance: COVID-19 can lead to severe acute respiratory distress syndrome (ARDS) where Veno-Venous Extra Corporeal Membrane Oxygenation (V-V ECMO) may be utilized for patients with severe respiratory failure. Our case report highlights a life threatening complication of V-V ECMO - intracranial hemorrhage (ICH), in a patient being treated for severe COVID-19 ARDS.

Case Presentation: A 41-year-old male of Indian ethnicity with no known comorbidities presented with an 8 day history of fever and dyspnoea. Read More

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January 2022

Long-term prognosis of patients with idiopathic Horner syndrome.

J Neurol 2022 05 28;269(5):2781-2783. Epub 2021 Nov 28.

Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

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Accuracy of the International Classification of Diseases, 9th Revision for Identifying Infantile Eye Disease.

Ophthalmic Epidemiol 2021 Nov 25:1-7. Epub 2021 Nov 25.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.

Purpose: To determine the predictive value of International Classification of Diseases, 9th Revision (ICD-9) codes for identifying infantile eye diagnoses.

Methods: Population-based retrospective cohort study of all residents of Olmsted County, Minnesota diagnosed at ≤1 year of age with an ocular disorder. The medical records of all infants diagnosed with any ocular disorder from January 1, 2005, through December 31, 2014, were identified. Read More

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November 2021

Comparison of out of hospital cardiac arrest due to acute brain injury vs other causes.

Am J Emerg Med 2022 Jan 30;51:304-307. Epub 2021 Oct 30.

Department of Emergency Medicine, Careggi University Hospital, Firenze, Italy.

Background: Acute brain injury (ABI) can cause out of hospital cardiac arrest (OHCA). The aim of this study was to compare clinical features, mortality and potential for organ donation in patients with OHCA due to ABI vs other causes.

Methods: From January 2017 to December 2018, all adult patients presenting to ED for OHCA were considered for the study. Read More

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January 2022

Anisocoria secondary to antiperspirant wipes in a pediatric population: a case series.

J AAPOS 2022 02 17;26(1):42-43. Epub 2021 Nov 17.

Department of Ophthalmology, Baylor College of Medicine, Houston, Texas; Department of Surgery, Texas Children's Hospital, Houston, Texas.

Acute-onset anisocoria or mydriasis in children carries a broad differential diagnosis and includes both benign and life-threatening causes, ranging from systemic or topical drug use to peripheral or central nervous system disease. The topical anticholinergic agent glycopyrronium (approved by the Food and Drug Administration in June 2018) is used to treat hyperhidrosis. We present the first case series of pediatric patients presenting with acute mydriasis due to exposure to glycopyrronium wipes. Read More

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February 2022

Anisocoria after scopolamine transdermal patch contamination: A case report.

Jin-Ho Joo

Medicine (Baltimore) 2021 Nov;100(46):e27887

Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.

Rationale: We report a case of anisocoria that occurred after contamination with a scopolamine transdermal patch, and introduce a diagnostic approach for anisocoria patients.

Patient Concerns: A 35-year-old woman with no past ophthalmologic history presented to the ophthalmology department complaining of a dilated pupil in the right eye. Corrected visual acuities was 20/20 in both eyes, and the intraocular pressures were 20 and 18 mm Hg in the right and left eye, respectively. Read More

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November 2021

The positive predictive value of photoscreening devices for amblyogenic conditions.

J AAPOS 2021 12 11;25(6):342.e1-342.e4. Epub 2021 Nov 11.

Eastern Virginia Medical School, Norfolk, Virginia.

Purpose: To determine the positive predictive value (PPV) of four photoscreening devices in detecting amblyogenic risk factors (ARFs).

Methods: This is a retrospective cohort study of 1,200 failed vision screenings (FVS) referred to a pediatric eye care practice from general pediatric practices over a 5-year period. Comprehensive eye examinations and cycloplegic refractions were performed. Read More

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December 2021

Early Prediction of Malignant Edema After Successful Recanalization in Patients with Acute Ischemic Stroke.

Neurocrit Care 2022 06 8;36(3):822-830. Epub 2021 Nov 8.

Department of Neurology, Center of Cerebrovascular Diseases, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Background: Postinterventional cerebral hyperdensities are common on non-contrast-enhanced computed tomography (CT) after endovascular thrombectomy in patients with acute ischemic stroke, which may reflect blood-brain barrier damage. The disruption of the blood-brain barrier may lead to malignant brain edema. The relationship between the extent of postinterventional cerebral hyperdensities and malignant brain edema is unclear. Read More

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Cardiogenic shock with highly complicated course after influenza A virus infection treated with vva-ECMO and Impella CP (ECMELLA): a case report.

BMC Cardiovasc Disord 2021 11 8;21(1):528. Epub 2021 Nov 8.

Division of Cardiology, Angiology and Intensive Medical Care, Department of Internal Medicine III (KIM III), Mid-German Heart Center, Faculty of Medicine, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.

Background: The value of mechanical circulatory support (MCS) in cardiogenic shock, especially the combination of the ECMELLA approach (Impella combined with ECMO), remains controversial.

Case Presentation: A previously healthy 33-year-old female patient was submitted to a local emergency department with a flu-like infection and febrile temperatures up to 39 °C. The patient was tested positive for type-A influenza, however negative for SARS-CoV-2. Read More

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November 2021

The Holmes-Adie Syndrome in the Mona Lisa of Leonardo da Vinci (1452-1519).

Acta Biomed 2021 11 3;92(5):e2021305. Epub 2021 Nov 3.

Studioso e ricercatore scientifico nel campo dell'arte, San Vito di Altivole, Treviso, Italy..

The literature describes that the renowned artwork of the genius of human anatomy, Leonardo da Vinci (1452-1519), known as Mona Lisa (1503-1506), is among one of the most enigmatic artworks in the History of Art. In this context, many details inserted on the composition of this artwork, including those related to Mona Lisa physical aspects' (anatomy) are controversial. The few known descriptions that provide some thorough indications about the woman who served as the model for this work, were written by Giorgio Vasari (1511-1574) in 1550. Read More

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November 2021

Safety of apraclonidine eye drops in diagnosis of Horner syndrome in an outpatient pediatric ophthalmology clinic.

J AAPOS 2021 12 2;25(6):336.e1-336.e4. Epub 2021 Nov 2.

UPMC Children's Hospital of Pittsburgh, Pediatric Ophthalmology, Strabismus, and Adult Motility, Pittsburgh, Pennsylvania; UPMC Eye Center, Pittsburgh, Pennsylvania; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address:

Purpose: To describe the efficacy and systemic side effects of apraclonidine drops 0.5% in children clinically suspected of having Horner syndrome.

Methods: The medical records of patients with clinically suspected Horner syndrome who underwent testing with apraclonidine 0. Read More

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December 2021

Cerebral hemorrhagic infarction was diagnosed subsequently after high-amplitude slow waves detected on processed electroencephalogram during sedation: a case report.

JA Clin Rep 2021 Oct 21;7(1):79. Epub 2021 Oct 21.

Department of Anesthesiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.

Background: Continuous electroencephalogram (EEG) monitoring is useful for assessing the level of sedation and detecting non-convulsive epileptic seizures and cerebral ischemia in the intensive care unit. This report describes a case of cerebral hemorrhagic infarction diagnosed after the detection of high-amplitude slow waves on processed EEG during sedation.

Case Presentation: A 68-year-old man who underwent cardiac surgery was sedated in the intensive care unit following an invasive procedure. Read More

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October 2021

[Horner's syndrome during vaginal delivery with epidural analgesia].

Agri 2021 Oct;33(4):272-275

Department of Obstetrics and Gynecology, Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey.

One of the most severe pains that women can experience throughout their lives is birth pain. Epidural analgesia is the ideal method to provide pain control in vaginal delivery. Horner syndrome is a rare complication of epidural analgesia. Read More

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October 2021