4,447 results match your criteria Animal Genetics[Journal]


Golden cats: The story goes on.

Anim Genet 2022 May 16. Epub 2022 May 16.

Institut NeuroMyoGène INMG-PNMG, CNRS UMR5261, INSERM U1315, Université Claude Bernard Lyon 1, Lyon, France.

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Genome-wide association study of three litter traits in Yorkshire pigs.

Anim Genet 2022 May 11. Epub 2022 May 11.

Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.

Litter traits are important in the development of production and economic profits of pigs. The object of this study was to perform genome-wide association studies (GWASs) for the total number born (TNB), number born alive (NBA) and number born healthy (NBH) traits in a Yorkshire population. By mixed model, we conducted GWASs with gcta software, and in total identified 3, 7 and 12 significant SNPs associated with TNB, NBA and NBH respectively: one on Sus scrofa chromosome (SSC) 2 (p = 7. Read More

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Genetic architectures and selection signatures of body height in Chinese indigenous donkeys revealed by next-generation sequencing.

Anim Genet 2022 May 10. Epub 2022 May 10.

Equine Center, China Agricultural University, Beijing, China.

Donkeys are widely distributed labour animals in the world. During the process of the domestication and artificial selection of domestic donkeys, body sizes show significant differences among different breeds of donkeys. Based on the genome resequencing data of 103 Chinese indigenous donkeys from 11 breeds (Biyang, Dezhou, Guangling, Hetian, Jiami, Kulun, Qingyang, Turfan, Tibetan, Xinjiang, and Yunnan), seven Spanish donkeys from two breeds (Zamorano~Leonés and Andalusian), and three wild donkeys, we investigated the population structures of Chinese domestic donkeys with different body sizes. Read More

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Evidence of rare misassemblies in the bovine reference genome revealed by population genetic metrics.

Anim Genet 2022 May 1. Epub 2022 May 1.

Research Institute for Farm Animal Biology (FBN), Institute of Genetics and Biometry, Dummerstorf, Germany.

Creation of the bovine reference assembly paved the way to develop the high-throughput genotyping arrays of the single nucleotide polymorphisms (SNPs) based on the available map coordinates that facilitated major advances in gene mapping and selection programs. The assembly flaws, however, may cause false results in the downstream gene mapping studies. The most recent bovine reference genome (ARS-UCD1. Read More

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Genetic diversity and selection signatures of four indigenous pig breeds from eastern China.

Anim Genet 2022 Apr 30. Epub 2022 Apr 30.

Department of Animal Science, College of Animal Science, Zhejiang University, Hangzhou, China.

Chinese indigenous pig breeds have been undergoing selection for thousands of years, and have become invaluable genetic sources over the world. To investigate the population structure and genetic diversity of Jinhua (JH), Longyou Black (LYW), Shengxian Spotted (SXH), and Lanxi Spotted (LXH) breeds, a total of 200 pigs belonging to 10 diverse population were genotyped using SNP chips. The results showed that LYW pigs exhibited higher level of heterozygosity than the other indigenous pigs. Read More

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Identification of imprinted genes in the skeletal muscle of newborn piglets by high-throughput sequencing.

Anim Genet 2022 Apr 28. Epub 2022 Apr 28.

Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.

Imprinted genes - exhibiting parent-specific transcription - play essential roles in the process of mammalian development and growth. Skeletal muscle growth is crucial for meat production. To further understand the role of imprinted genes during the porcine skeletal muscle growth, DNA-seq and RNA-seq were used to explore the characteristics of imprinted genes from porcine reciprocal crosses. Read More

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Shadow coat colour in American mink associated with a missense mutation in the KIT gene.

Anim Genet 2022 Apr 28. Epub 2022 Apr 28.

Centre for Genetics and Life Science, Sirius University of Science and Technology, Sochi, Russia.

The classical genetic analysis describes more 35 mutations that are involved in the formation of the American mink (Neovison vison) fur colour phenotype. To date, only eight of these mutations have been linked to specific genes. Shadow is a member of the commercially valuable Black cross colour family. Read More

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Identification of two new recessive MC1R alleles in red-coloured Evolèner cattle and other breeds.

Anim Genet 2022 Jun 22;53(3):427-435. Epub 2022 Apr 22.

Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Sequence variations in the melanocortin-1 receptor (MC1R) gene are associated with melanism in different animal species. Six functionally relevant alleles have been described in cattle to date. In a hypothesis-free approach we performed a genome-wide allelic association study with black, red and wild-coloured cattle of three Alpine cattle breeds (Eringer, Evolèner and Valdostana), revealing a single significant association signal close to the MC1R gene. Read More

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A de novo start-lost variant in ANKRD28 in a Holstein calf with dwarfism.

Anim Genet 2022 06 22;53(3):470-471. Epub 2022 Apr 22.

Vetsuisse Faculty, Institute of Genetics, University of Bern, Bern, Switzerland.

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A genetic investigation of equine recurrent uveitis in the Icelandic horse breed.

Anim Genet 2022 Jun 22;53(3):436-440. Epub 2022 Apr 22.

Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California Davis, Davis, California, USA.

Equine recurrent uveitis (ERU) is an autoimmune disease defined by inflammation of the uveal tract of the eye. The cause of ERU is thought to be complex, involving both genetic and environmental factors. The purpose of this study was to investigate potential genetic risk factors for ERU in the Icelandic horse. Read More

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Genomic analysis of 10 years of artificial selection in community-based breeding programs in two Ethiopian indigenous sheep breeds.

Anim Genet 2022 Jun 15;53(3):447-451. Epub 2022 Apr 15.

Small Ruminant Genomics, International Centre for Agricultural Research in the Dry areas (ICARDA), Addis Ababa, Ethiopia.

In recent times, community-based breeding programs (CBBPs) have been advocated as the best strategy for genetic improvement of local breeds in smallholder farms in developing countries. Since 2009, CBBPs have been implemented for Ethiopian Bonga and Menz sheep to improve growth rates resulting in significant genetic gains in 6-month weights. With the hypothesis that selection could be impacting their genomes, we systematically screened for possible genome changes in the two breeds by analyzing 600K BeadChip genotype data of 151 individuals (with the highest breeding values for 6-month weights) from CBBP flocks against 98 individuals from non-CBBP flocks. Read More

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Transcriptomic profile of longissimus thoracis associated with fatty acid content in Nellore beef cattle.

Anim Genet 2022 Jun 6;53(3):264-280. Epub 2022 Apr 6.

School of Agricultural and Veterinary Sciences (FCAV), São Paulo State University (UNESP), Jaboticabal, Brazil.

The beef fatty acid (FA) profile has the potential to impact human health, and displays polygenic and complex features. This study aimed to identify the transcriptomic FA profile in the longissimus thoracis muscle in Nellore beef cattle finished in feedlot. Forty-four young bulls were sampled to assess the beef FA profile by considering 14 phenotypes and including differentially expressed genes (DEG), co-expressed (COE), and differentially co-expressed genes (DCO) analyses. Read More

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Integrative analysis of circRNAs from Yangtze River Delta white goat neck skin tissue by high-throughput sequencing (circRNA-seq).

Anim Genet 2022 Jun 5;53(3):405-415. Epub 2022 Apr 5.

College of Animal Science and Technology, Yangzhou University, Yangzhou, China.

The Yangtze River Delta white goat is a unique goat species that can produce superior-quality brush hair. The formation of this brush hair is controlled by a series of critical genes and related signaling pathways. Circular RNAs (circRNAs), are ubiquitous endogenous non-coding RNAs that regulate many biological and physiological processes in mammals. Read More

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Understanding the role of myoglobin content in Iberian pigs fattened in an extensive system through analysis of the transcriptome profile.

Anim Genet 2022 Jun 30;53(3):352-367. Epub 2022 Mar 30.

Departamento de Mejora Genética Animal, INIA-CSIC, Madrid, Spain.

Meat color is the first perceived sensory feature and one of the most important quality traits. Myoglobin is the main pigment in meat, giving meat its characteristic cherry-red color, highly appreciated by the consumers. In the current study, we used the RNA-seq technique to characterize the longissimus dorsi muscle transcriptome in two groups of Iberian pigs with divergent breeding values for myoglobin content. Read More

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Genetic polymorphisms within the ETAA1 gene associated with growth traits in Chinese sheep breeds.

Anim Genet 2022 Jun 30;53(3):460-465. Epub 2022 Mar 30.

Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.

Ewing tumor-associated antigen 1 (ETAA1) is an important candidate gene for fat deposition in sheep. This study aimed to investigate the indel variations in the ETAA1 gene and their associations with growth traits in the 1619 sheep. The polymorphism information content of this indel ranged from 0. Read More

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Preliminary identification and analysis of differential RNA editing between higher and lower backfat thickness pigs using DNA-seq and RNA-seq data.

Anim Genet 2022 Jun 27;53(3):327-339. Epub 2022 Mar 27.

Institute of Animal Science, State Key Laboratory of Animal Nutrition, Chinese Academy of Agricultural Sciences, Beijing, China.

RNA editing is an essential post-transcriptional regulatory mechanism. However, few studies have investigated the functional RNA edits in the economic traits of livestock on a genome-wide scale. Pigs are one of the most important livestock species and their fat is the principal organ involved in the regulation of adipose deposition. Read More

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Comparison of lipid metabolism between broodstock and hybrid offspring in the hepatopancreas of juvenile shrimp (Macrobrachium nipponense): Response to chronic ammonia stress.

Anim Genet 2022 Jun 20;53(3):393-404. Epub 2022 Mar 20.

School of Life Science, East China Normal University, Shanghai, 200241, China.

Ammonia nitrogen is a major pollutant that causes great physiological harm to crustaceans in culture. In this study, we conducted a 28 day chronic ammonia nitrogen stress experiment with broodstock populations (Dianshan, DS) and hybrid offspring populations (DS ♀ × CD (Changjiang ♂ × Dongting ♀), SCD) exposed to 0, 1 and 10 mg/L of ammonia concentrations. A 28 day feeding trial and chronic ammonia nitrogen stress were used to investigate the effects on the growth performance, histological structure and lipid metabolism of juvenile shrimp, Macrobrachium nipponense. Read More

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An analysis of skin thickness in the Dezhou donkey population and identification of candidate genes by RNA-seq.

Anim Genet 2022 Jun 21;53(3):368-379. Epub 2022 Mar 21.

College of Animal Science and Technology, China Agricultural University, Beijing, China.

The aim of the present study was to analyze the main factors that have a significant impact on skin thickness, and to further identify the genes and signaling pathways regulating skin growth by RNA-seq in Dezhou donkeys. Skin samples from different body regions of 15 slaughtered donkeys were obtained to study variations in skin thickness over the bodies. Skin thickness data for another 514 donkeys was obtained by minimally invasive skin sampling from the back, and measurements of the donkeys' body size traits and pedigree data were also collected. Read More

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Comparison of immune defense and antioxidant capacity between broodstock and hybrid offspring of juvenile shrimp (Macrobrachium nipponense): Response to acute ammonia stress.

Anim Genet 2022 Jun 18;53(3):380-392. Epub 2022 Mar 18.

School of Life Science, East China Normal University, Shanghai, China.

Ammonia is a major environmental pollutant in the aquatic system that poses a great threat to the health of shrimp. Macrobrachium nipponense, as one of the large-yield farmed shrimp, is facing germplasm degradation. Genetic improvement through hybridization is one of the effective methods to solve this problem. Read More

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Fatty acid desaturase 2 affects the milk-production traits in Chinese Holsteins.

Anim Genet 2022 Jun 15;53(3):422-426. Epub 2022 Mar 15.

Department of Animal Genetics and Breeding, College of Animal Science and Technology, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing, China.

As a member of the fatty acid desaturase family, fatty acid desaturase 2 (FADS2) gene is a rate-limiting enzyme in the synthesis of unsaturated fatty acids and within/near to the reported QTL regions for milk-production traits. We previously found that FADS2 is differentially expressed during different lactations of Chinese Holstein cows, and participates in lipid metabolic processes by influencing the insulin, PI3K-Akt, MAPK, AMPK, mTOR and PPAR signaling pathways. Therefore, we considered this gene as a candidate gene for milk-production traits. Read More

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Comparison of genomic prediction methods for residual feed intake in broilers.

Anim Genet 2022 Jun 15;53(3):466-469. Epub 2022 Mar 15.

State Key Laboratory of Animal Nutrition, Key Laboratory of Animal (Poultry) Genetics Breeding and Reproduction, Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.

Residual feed intake (RFI) is a measure of the feed efficiency of animals. Previous studies have identified SNPs associated with RFI. The objective of this study was to compare the GBLUP model with the GA-BLUP model including previously identified associated SNPs. Read More

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Functional characterization of cAMP signaling of variant porcine MC1R alleles in PK15 cells.

Anim Genet 2022 Jun 15;53(3):317-326. Epub 2022 Mar 15.

State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510006, China.

The melanocortin 1 receptor (MC1R), encoded by the classical extension (E) coat color locus, is expressed on the surface of melanocytes and plays a critical role in switching melanin synthesis from pheomelanin (red/yellow) to eumelanin (black/brown). Different MC1R alleles associated with various coat color patterns in pigs have been identified over the past decades. However, functional analysis of variant porcine MC1R alleles has not yet been performed. Read More

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Cross-species conservation of a transposase-linked element enables genetic sexing of commercial populations of Russian sturgeon (Acipenser gueldenstaedtii).

Anim Genet 2022 Jun 14;53(3):441-446. Epub 2022 Mar 14.

Institute of Animal Science, Agricultural Research Organization, Rishon LeTsiyon, Israel.

All-female culture of sturgeon is essential for efficient caviar production. However, Russian sturgeon (Acipenser gueldenstaedtii) does not exhibit external sexual dimorphism, and therefore, commercial farms apply gonadal endoscopy or ultrasound at the earliest age of 4-5 years to separate the sexes, with ~90% accuracy. Recently, a dominant genomic marker (AllWSEX2) has been found with association to femaleness in sturgeons. Read More

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Broad maternal geographic origin of domestic sheep in Anatolia and the Zagros.

Anim Genet 2022 Jun 14;53(3):452-459. Epub 2022 Mar 14.

LECA, CNRS, Université Grenoble Alpes, Université Savoie Mont Blanc, Grenoble, France.

We investigated the controversial origin of domestic sheep (Ovis aries) using large samples of contemporary and ancient domestic individuals and their closest wild relatives: the Asiatic mouflon (Ovis gmelini), the urial (Ovis vignei) and the argali (Ovis ammon). A phylogeny based on mitochondrial DNA, including 213 new cytochrome-b sequences of wild Ovism confirmed that O. gmelini is the maternal ancestor of sheep and precluded mtDNA contributions from O. Read More

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Altered fibrinogen level and fibrin clot structure in myostatin homozygous mutant pig.

Anim Genet 2022 Jun 13;53(3):307-316. Epub 2022 Mar 13.

Jilin Provincial Key Laboratory of Transgenic Animal and Embryo Engineering, Yanbian University, Yanji, Jilin, 133002, China.

Obesity is associated with increased serum fibrinogen level. Myostatin (MSTN), a strong inhibitor of skeletal muscle growth, is recognized as a potential target for obesity. However, the effect of MSTN inhibition on fibrinogen is not largely known. Read More

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Genome-wide analysis suggests multiple domestication events of Chinese local pigs.

Anim Genet 2022 Jun 11;53(3):293-306. Epub 2022 Mar 11.

State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China.

Chinese local pigs have abundant phenotypes as a result of different cultures and habits of Chinese populations, geographic constraints and the long history of pig domestication. A comprehensive investigation of local Chinese pigs will benefit biodiversity research and future breeding practices. However, their classification and demographic history are not yet clear. Read More

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