4,315 results match your criteria Animal Genetics[Journal]


Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy.

Anim Genet 2021 May 10. Epub 2021 May 10.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, North Carolina State University, A227, Main CVM, 1060 William Moore Drive, Raleigh, NC, 27607, USA.

Hypertrophic cardiomyopathy (HCM) is the most common cause of heart disease in the domestic cat with a genetic predisposition in a few breeds. In the Maine Coon and Ragdoll breeds, two variants associated with the HCM phenotype have been identified in the cardiac myosin binding protein C gene (MYBPC3; p.Ala31Pro and p. Read More

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Siberian cats help in solving part of the mystery surrounding golden cats.

Anim Genet 2021 May 10. Epub 2021 May 10.

VetAgro Sup, Univ. Lyon, 1 avenue Bourgelat, 69280, Marcy-l'Etoile, France.

Golden cats have been appreciated since the beginning of the cat fancy. Golden is a modification of the tabby coat. In the Siberian breed, a specific golden phenotype, named sunshine, has been described. Read More

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Association of inbreeding and regional equine leucocyte antigen homozygosity with the prevalence of insect bite hypersensitivity in Old Kladruber horse.

Anim Genet 2021 May 10. Epub 2021 May 10.

Faculty of Agriculture, University of Zagreb, Svetošimunska cesta 25, Zagreb, 10000, Croatia.

Inbreeding depression is the reduction of performance caused by mating of close relatives. In livestock populations, inbreeding depression has been traditionally estimated by regression of phenotypes on pedigree inbreeding coefficients. This estimation can be improved by utilising genomic inbreeding coefficients. Read More

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Identification of quantitative trait loci associated with calmness and gentleness in honey bees using whole-genome sequences.

Anim Genet 2021 May 10. Epub 2021 May 10.

Agroscope, Animal GenoPhenomics, Rte de la Tioleyre 4, Posieux, 1725, Switzerland.

The identification of quantitative trait loci (QTL) through genome-wide association studies (GWAS) is a powerful method for unravelling the genetic background of selected traits and improving early-stage predictions. In honey bees (Apis mellifera), past genetic analyses have particularly focused on individual queens and workers. In this study, we used pooled whole-genome sequences to ascertain the genetic variation of the entire colony. Read More

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Evolution of the sheep industry and genetic research in the United States: opportunities for convergence in the twenty-first century.

Anim Genet 2021 May 6. Epub 2021 May 6.

National Animal Germplasm Program, United States Department of Agriculture, Agricultural Research Service, Fort Collins, CO, 80521, USA.

The continuous development and application of technology for genetic improvement is a key element for advancing sheep production in the United States. The US sheep industry has contracted over time but appears to be at a juncture where a greater utilization of technology can facilitate industry expansion to new markets and address inefficiencies in traditional production practices. Significant transformations include the increased value of lamb in relation to wool, and a downtrend in large-scale operations but a simultaneous rise in small flocks. Read More

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A natural knockout of the MYO7A gene leads to pre-weaning mortality in pigs.

Anim Genet 2021 May 6. Epub 2021 May 6.

Topigs Norsvin Research Center, Beuningen, The Netherlands.

The pig breeding system provides a unique framework to study recessive defects and the consequence on the phenotype. We examined a commercial synthetic Duroc population for recessive defects and identified a haplotype on chromosome 9 significantly affecting pre-weaning mortality. To identify the causal variant underlying the mortality, we examined sequence data of four carrier animals and 21 non-carrier animals from the same population. Read More

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Analysis of recently duplicated TYRP1 genes and their effect on the formation of black patches in Oujiang-color common carp (Cyprinus carpio var. color).

Anim Genet 2021 May 3. Epub 2021 May 3.

Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai, 201306, China.

Tyrp1 gene, as a member of the tyrosinase family, has undergone a recent duplication event during fourth-round whole genome duplication in common carp. In this research, three Tyrp1 genes were identified in Oujiang-color common carp (Cyprinus carpio var. color). Read More

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Equine STX17 intronic triplication confirmed by droplet digital PCR analysis of its breakpoints.

Anim Genet 2021 May 3. Epub 2021 May 3.

Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Wolynska 33, Poznan, 60-637, Poland.

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Mitochondrial DNA variation of Nigerian dromedary camel (Camelus dromedarius).

Anim Genet 2021 May 2. Epub 2021 May 2.

State Key Laboratory of Genetic Resources and Evolution & Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China.

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Molecular sex identification in Japanese quail (Coturnix japonica).

Anim Genet 2021 Apr 21. Epub 2021 Apr 21.

Department of Animal Genetics and Conservation, Institute of Animal Sciences, Warsaw University of Life Sciences, Warszawa, Poland.

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Low diversity of mitochondrial DNA in fancy pigeons (Columba livia) revealed by partial D-loop sequencing.

Anim Genet 2021 Jun 13;52(3):382. Epub 2021 Apr 13.

Department of Animal Molecular Biology, National Research Institute of Animal Production, Krakowska 1, Balice, 32-083, Poland.

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Identification of a large dataset of SNPs in hair-fin anchovy (Setipinna tenuifilis) based on RAD-seq.

Anim Genet 2021 Jun 11;52(3):371-374. Epub 2021 Apr 11.

National Engineering Laboratory of Marine Germplasm Resources Exploration and Utilization, Zhejiang Ocean University, No.1 Haidanan road, Zhoushan, 316022, China.

Hair-fin anchovy (Setipinna tenuifilis) is an economically important fish distributed in the West Indian Ocean and the Northwest Pacific Ocean. In this study, 154 individuals in eight populations of S. tenuifilis were sequenced and 850 million raw reads were obtained using restriction site-associated DNA sequencing (RAD-seq). Read More

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Parsing the microRNA genetics basis regulating skeletal muscle fiber types and meat quality traits in pigs.

Anim Genet 2021 Jun 11;52(3):292-303. Epub 2021 Apr 11.

Department of Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China.

Muscle fibers are closely related to human diseases and livestock meat quality. However, the genetics basis of microRNAs (miRNAs) in regulating muscle fibers is not completely understood. In this study, we constructed the whole genome-wide miRNA expression profiles of porcine fast-twitch muscle [biceps femoris (Bf)] and slow-twitch muscle [soleus (Sol)], and identified hundreds of miRNAs, including four skeletal muscle-highly expressed miRNAs, ssc-miR-378, ssc-let-7f, ssc-miR-26a, and ssc-miR-27b-3p. Read More

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Genomic inbreeding and selection signatures in the local dairy breed Icelandic Cattle.

Anim Genet 2021 Jun 8;52(3):251-262. Epub 2021 Apr 8.

Center for Quantitative Genetics and Genomics, Aarhus University, Tjele, 8830, Denmark.

Icelandic Cattle is the only dairy cattle breed native to Iceland. It currently numbers ca. 26 000 breeding females. Read More

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Mining the 99 Lives Cat Genome Sequencing Consortium database implicates genes and variants for the Ticked locus in domestic cats (Felis catus).

Anim Genet 2021 Jun 29;52(3):321-332. Epub 2021 Mar 29.

School of Health and Behavioural Sciences, University of the Sunshine Coast, Sippy Downs, Qld, 4558, Australia.

Tabby patterns of fur coats are defining characteristics in wild and domestic felids. Historically, three autosomal alleles at one locus (Tabby): Abyssinian (T ; a.k. Read More

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De novo assembly and annotation of the North American bison (Bison bison) reference genome and subsequent variant identification.

Anim Genet 2021 Jun 29;52(3):263-274. Epub 2021 Mar 29.

Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, 77845, USA.

Genomic tools have improved the ability to manage bison populations and enhanced efforts to conserve this iconic species. These tools have been particularly useful for detecting introgression of cattle genome within bison herds but are limited by the need to use the cattle genome as a surrogate for mapping reads. This complicates efforts to distinguish the species of origin of chromosomal segments in individual bison at the genomic level. Read More

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Genome-wide association study of fleece traits in Inner Mongolia Cashmere goats.

Anim Genet 2021 Jun 28;52(3):375-379. Epub 2021 Mar 28.

College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.

Inner Mongolia Cashmere goat is a well-known local cashmere goat breed in China. It is famous for excellent fleece quality and a significant advantage in cashmere yield compared to other cashmere goat breeds. In this study, a genome-wide association study was used to investigate fiber length, fiber diameter, and cashmere yield of 192 Inner Mongolia Cashmere goats using the Illumina GoatSNP52K Beadchip panel. Read More

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The previously reported LRP4 c.4940C>T variant is not associated with syndactyly in cattle.

Anim Genet 2021 Jun 22;52(3):380-381. Epub 2021 Mar 22.

Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camden, NSW, 2570, Australia.

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All-male production by marker-assisted selection for sex determining loci of admixed Oreochromis niloticus and Oreochromis aureus stocks.

Anim Genet 2021 Jun 19;52(3):361-364. Epub 2021 Mar 19.

Institute of Animal Science, Agricultural Research Organization, Rishon LeTsiyon, 7528809, Israel.

Crossing Oreochromis niloticus (On) females with Oreochromis aureus (Oa) males results in all-male progeny that are essential for effective tilapia farming. However, a reproductive barrier between these species limits mating and mass-fry production. One approach to overcoming this barrier is to select parental stocks of mixed genetic backgrounds, which allow interspecific reproductive recognition, while closely maintaining the genetic profiles for sex-determination (SD) of the respective purebred species. Read More

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Investigating the population structure and genetic diversity of Arabian horses in Oman using SNP markers.

Anim Genet 2021 Jun 17;52(3):304-310. Epub 2021 Mar 17.

Department of Animal and Veterinary Sciences, College of Agriculture and Marine Sciences, Sultan Qaboos University, PO Box 34, Al Khod, Muscat, 123, Oman.

Arabian horses were selected for metabolic efficiency, beauty, efficiency and endurance. Therefore, Bedouins have for centuries traced their prized horses' ancestries. With the establishment of the World Arabian Horse Organization (WAHO), registration of Arabian horses became centralized and countries worldwide registered them in its database. Read More

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A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells.

Anim Genet 2021 Jun 11;52(3):275-283. Epub 2021 Mar 11.

Agriculture and Food, Commonwealth Science and Industrial Research Organisation, 306 Carmody Road, St Lucia, Queensland, 4067, Australia.

The Wagyu breed of taurine cattle possess favourable genetics for intramuscular fat (IMF) but genomic loci associated with the trait remain under characterised. Here, we report the identification of a previously unidentified genomic region possessing a particular haplotype structure in Wagyu. Through deployment of a genome-wide haplotype detection analysis that captures regions conserved in a target population but not other populations we screened 100 individual Wagyu and contrasted them with 100 individuals from two independent comparison breeds, Charolais and Angus, using high-density SNPs. Read More

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A missense mutation in the FZD7 gene is associated with dilution of the red areas of the coat in Montbéliarde cattle.

Anim Genet 2021 Jun 8;52(3):351-355. Epub 2021 Mar 8.

INRAE, AgroParisTech, Université Paris-Saclay, GABI, Jouy-en-Josas, 78350, France.

Recently, a new genetically autosomal recessive color phenotype emerged in the red pied bovine Montbéliarde breed. It is characterized by a dilution of the red areas of the coat and was denominated 'milca'. A genome-wide homozygosity scan of 106 cases followed by haplotype analysis revealed a candidate region within BTA2 between positions 89. Read More

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Gene mapping reveals the association between tyrosine protein kinase Abl1 and the silk yield of Bombyx mori.

Anim Genet 2021 Jun 8;52(3):342-350. Epub 2021 Mar 8.

State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, College of Biotechnology, Southwest University, Chongqing, 400715, China.

The Z chromosome of the silkworm contains a major gene that influences silk yield. This major locus on chromosome Z accounts for 35.10% of the phenotypic variance. Read More

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Potential functional variants in AHR signaling pathways are associated with age at puberty in swine.

Anim Genet 2021 Jun 5;52(3):284-291. Epub 2021 Mar 5.

USDA, ARS, U.S. Meat Animal Research Center, Clay Center, NE, 68933, USA.

Puberty in female pigs is defined as age at first estrus and gilts that have an earlier age at puberty are more likely to have greater lifetime productivity. Because age at puberty is predictive for sow longevity and lifetime productivity, but not routinely measured in commercial herds, it would be beneficial to use genomic or marker-assisted selection to improve these traits. A GWAS at the US Meat Animal Research Center (USMARC) identified several loci associated with age at puberty in pigs. Read More

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Genomic scan revealed KIT gene underlying white/gray plumage color in Chinese domestic geese.

Anim Genet 2021 Jun 28;52(3):356-360. Epub 2021 Feb 28.

State Key Laboratory of Animal Nutrition, Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100094, China.

Goose is an important type of domesticated poultry. The wild geese that are regarded as the ancestors of modern domestic geese present gray plumage. Domesticated, geese have both white and gray feathers. Read More

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Polymorphisms in canine immunoglobulin heavy chain gene cluster: a double-edged sword for diabetes mellitus in the dog.

Anim Genet 2021 Jun 23;52(3):333-341. Epub 2021 Feb 23.

Department of Animal Production, Veterinary Faculty, Complutense University of Madrid, Madrid, 28040, Spain.

Insulin deficiency diabetes (IDD) in dogs is an endocrine disease similar to human type 1 diabetes. There are breeds more commonly affected, such as Yorkshire Terrier and Samoyed, suggesting an underlying genetic component. However, the genetic basis for canine diabetes mellitus (DM) is not fully established. Read More

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A comparative whole genome sequencing analysis identified a candidate locus for lack of operculum in cultivated gilthead seabream (Sparus aurata).

Anim Genet 2021 Jun 20;52(3):365-370. Epub 2021 Feb 20.

Division of Animal Sciences, Department of Agricultural and Food Sciences, University of Bologna, Viale Giuseppe Fanin 46, Bologna, 40127, Italy.

The gilthead seabream (Sparus aurata, Sparidae family) is commonly used for aquaculture. Despite its great economic value, several problems in its cultivation remain. One of the major concerns is the high frequency of morphological abnormalities occurring during the early developmental stages. Read More

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A high-density genetic linkage map for Chinese perch (Siniperca chuatsi) using 2.3K genotyping-by-sequencing SNPs.

Anim Genet 2021 Jun 18;52(3):311-320. Epub 2021 Feb 18.

College of Fisheries, Key Lab of Freshwater Animal Breeding, Ministry of Agriculture, Engineering Research Center of Green development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, Huazhong Agricultural University, Wuhan, China.

Chinese perch, Siniperca chuatsi (Basilewsky), is one of the most commercially important cultured fishes in China. In the present study, a high-density genetic linkage map of Chinese perch was constructed by genotyping-by-sequencing technique with an F1 mapping panel containing 190 progenies. A total of 2328 SNPs were assigned to 24 linkage groups (LGs), agreeing with the chromosome haploid number in this species (n = 24). Read More

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The equine graying with age mutation of the STX17 gene: A copy number study using droplet digital PCR reveals a new pattern.

Anim Genet 2021 Apr 7;52(2):223-227. Epub 2021 Feb 7.

Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Wolynska 33, Poznan, 60-637, Poland.

The equine graying with age causative mutation in the syntaxin-17 gene (STX17) has been known for over a decade, but proper genotyping of this variant remains challenging due to its molecular character (4.6-kb tandem duplication). Precise information on gray mutation status is important for horse breeders and veterinarians, since gray homozygous horses are more prone to developing aggressive melanoma tumors than heterozygotes. Read More

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A genome-wide association study reveals a quantitative trait locus for calf mortality on chromosome 9 in Japanese Black cattle.

Authors:
S Sasaki T Ibi

Anim Genet 2021 Apr 5;52(2):214-216. Epub 2021 Feb 5.

Graduate School of Environmental and Life Science, Okayama University, Tsushima-naka, Okayama, 700-8530, Japan.

Calf mortality is a major problem affecting cattle production. To identify genetic variants associated with calf mortality in Japanese Black cattle, we evaluated calf mortality as a categorical trait using a threshold model and conducted a GWAS. We identified two SNPs between 32 549 297 and 32 606 924 bp on bovine chromosome 9 that were significantly associated with calf mortality from 61 to 180 days after birth. Read More

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