8,733 results match your criteria Angiosarcoma


Prevalence, distribution, and clinical characteristics of hemangiosarcoma-associated skeletal muscle metastases in 61 dogs: A whole body computed tomographic study.

J Vet Intern Med 2019 Feb 22. Epub 2019 Feb 22.

Service of Diagnostic Imaging, I Portoni Rossi Veterinary Hospital, Zola Predosa, Bologna, Italy.

Background: Skeletal muscle metastases (SMMs) have been described sporadically in canine oncology.

Hypothesis/objectives: To determine the prevalence, localization, and clinical signs of SMMs associated with hemangiosarcoma (HSA) in a population of dogs presented for whole body computed tomography (CT).

Animals: Dogs with a histologically confirmed HSA and a tissue core specimen or fine needle aspirate of suspected metastatic lesions were included in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jvim.15456DOI Listing
February 2019

Retiform Hemangioendothelioma of the Gluteal Region: A Case Report.

Saudi J Med Med Sci 2018 Sep-Dec;6(3):165-168. Epub 2018 Aug 14.

Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Retiform hemangioendothelioma is a locally aggressive, rarely metastasizing, low-grade angiosarcoma characterized by intercommunicating vascular channels lined by hobnail or cuboidal endothelial cells, flanked by lymphocyte and hyaline sclerosis. Neoplastic endothelial cells usually express von Willebrand factor, CD31 and CD34, while the lymphocytic infiltrate shows a mixture of CD3+, T and CD20+ B cells. The authors describe a case of a 76-year-old female who presented with a soft, painless, ill-defined mass measuring 9 cm in her right gluteal region for the past 15 years, clinically suggestive of a lipoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/sjmms.sjmms_145_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196697PMC

Prevalence of pulmonary nodules in dogs with malignant neoplasia as determined by CT.

Vet Radiol Ultrasound 2019 Feb 19. Epub 2019 Feb 19.

Department of Clinical Sciences and Services, The Royal Veterinary College, Hertfordshire, United Kingdom.

In order to estimate the prevalence of pulmonary nodules in dogs with nonpulmonary malignant neoplasia, medical record descriptions of CT findings in dogs diagnosed with nonpulmonary malignant neoplasia were reviewed retrospectively. A total of 536 dogs were sampled from a single hospital. For malignant neoplasms with >10 affected individuals, prevalence of multiple pulmonary nodules at first CT was hemangiosarcoma 24 of 58 (41%), osteosarcoma 14 of 55 (26%), carcinoma 20 of 80 (25%), histiocytic sarcoma five of twenty-one (24%), soft tissue sarcoma 13 of 57 (23%), adenocarcinoma 11 of 60 (18%), melanoma five of thirty-seven (14%), lymphoma 10 of 76 (13%), mast cell tumor two of forty-seven (4%), and squamous cell carcinoma zero of seventeen (0%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vru.12723DOI Listing
February 2019

Multiple hepatic metastases of cardiac angiosarcoma.

Autops Case Rep 2018 Oct-Dec;8(4):e2018048. Epub 2018 Oct 9.

University of Campinas (Unicamp), School of Medical Sciences, Department of Gastroenterology (Gastrocentro). Campinas, SP, Brazil.

The differential diagnosis of hepatic focal lesions is challenging because the etiology can be inflammatory, infectious, and even neoplastic. A rare cause of metastatic liver nodules is cardiac angiosarcoma. We report a case of this tumor, which was diagnosed only after autopsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4322/acr.2018.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360823PMC
October 2018

Tumor necrosis factor-related apoptosis inducing ligand induces apoptosis in canine hemangiosarcoma cells in vitro.

Vet Comp Oncol 2019 Feb 15. Epub 2019 Feb 15.

Laboratory of Veterinary Pathology, Gifu University, Gifu, Japan.

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is an apoptosis-inducing cytokine that shows potential therapeutic value for human neoplasms, and is effective in some canine tumors; however, its potential for killing canine hemangiosarcoma (HSA) cells is unknown. Thus, we evaluated the proapoptotic effect of TRAIL in nine canine HSA cell lines. Cells (JuA1, JuB2, JuB2-1, JuB4, Re11, Re12, Re21, Ud2, and Ud6) were cultured with three recombinant human TRAILs (rhTRAILs): TRAIL-TEC derived from Escherichia coli, TRAIL-TL derived from mammalian cells, and izTRAIL containing an isoleucine-zippered structure that facilitates trimerization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vco.12471DOI Listing
February 2019
1 Read

Clinical and imaging manifestations of primary cardiac angiosarcoma.

BMC Med Imaging 2019 02 14;19(1):16. Epub 2019 Feb 14.

Magnetic Resonance Room, Sheng Li Oilfield Central Hospital, Shan Dong, 257034, China.

Background: To investigate the CT manifestations of primary cardiac angiosarcoma.

Methods: The clinical and CT data for 9 patients with cardiac angiosarcoma were retrospectively analyzed.

Results: The lesions in all nine cases were located in the right atrium. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12880-019-0318-4DOI Listing
February 2019
0.983 Impact Factor

Epithelioid Vascular Tumors: A Review.

Adv Anat Pathol 2019 Feb 12. Epub 2019 Feb 12.

Department of Pathology, Cleveland Clinic, Cleveland, OH.

Vascular tumors are a diagnostically challenging area. This is particularly true in the case of epithelioid vascular tumors. Not only is the distinction between different epithelioid vascular tumors challenging, but also the differential diagnosis may be substantially expanded by the inclusion of melanoma, carcinomas, and other epithelioid soft tissue tumors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAP.0000000000000228DOI Listing
February 2019
3 Reads

Sarcomatoid Carcinoma With Quasi-Complete Loss of Cytokeratin Expression or Keratin-Positive Atypical Fibroxanthoma.

Int J Surg Pathol 2019 Feb 14:1066896919830208. Epub 2019 Feb 14.

1 University of Montreal, Montreal, Quebec, Canada.

We report the case of a 94-year-old man with a rapidly growing nodule on the preauricular area, which on histology showed a poorly differentiated spindle cell tumor with negative p63 and p40 antibody immunostains, negative high- and low-molecular-weight cytokeratins albeit for a focal expression of cytokeratin AE1/AE3. Spindle cell melanoma, angiosarcoma, and leiomyosarcoma were excluded. We explore the diagnostic approach to this challenging conundrum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1066896919830208DOI Listing
February 2019
1 Read

Cutaneous Angiosarcoma Secondary to Lymphoedema or Radiation Therapy - A Systematic Review.

Authors:
M Co A Lee A Kwong

Clin Oncol (R Coll Radiol) 2019 Feb 6. Epub 2019 Feb 6.

Division of Breast Surgery, Department of Surgery, The University of Hong Kong, Hong Kong; Division of Breast Surgery, Department of Surgery, Queen Mary Hospital, Hong Kong. Electronic address:

Aims: Secondary angiosarcoma is known to be associated with lymphoedema or radiation after cancer treatment. This systematic review aims to evaluate the clinical features and outcomes of secondary angiosarcoma commonly arising after breast cancer treatment.

Materials And Methods: A systematic review was carried out according to the PRISMA protocol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clon.2019.01.009DOI Listing
February 2019

Primary renal angiosarcoma with extensive hemorrhage: CT and MRI findings.

Int Braz J Urol 2018 Nov 30;44. Epub 2018 Nov 30.

Department of Pathology, Chonnam National University Medical School, Gwangju, South Korea.

Primary angiosarcomas of the kidney are very rare, but highly aggressive tumors showing poor prognosis. Patients frequently complain of flank pain, hematuria, or a palpable mass. We present a case of primary renal angiosarcoma occurring in a 61-year-old man. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/S1677-5538.IBJU.2018.0375DOI Listing
November 2018

Marrow involvement by metastatic spindle cell angiosarcoma.

Blood 2019 Feb;133(6):618

Tuen Mun Hospital.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2018-10-876359DOI Listing
February 2019

Tumoral pulmonary hypertension.

Eur Respir Rev 2019 Mar 6;28(151). Epub 2019 Feb 6.

National Pulmonary Hypertension Service, Royal Brompton Hospital, Imperial College London, London, UK.

Tumoral pulmonary hypertension (PH) comprises a variety of subtypes in patients with a current or previous malignancy. Tumoral PH principally includes the tumour-related pulmonary microvascular conditions pulmonary tumour microembolism and pulmonary tumour thrombotic microangiopathy. These inter-related conditions are frequently found in specimens but are notoriously difficult to diagnose The outlook for patients remains extremely poor although there is some emerging evidence that pulmonary vasodilators and anti-inflammatory approaches may improve survival. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/16000617.0065-2018DOI Listing
March 2019
1 Read

Early appearance of post-radiation angiosarcoma of the breast.

Breast J 2019 Feb 6. Epub 2019 Feb 6.

General Surgery Department, Division of Surgical Oncology, University of Illinois at Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tbj.13217DOI Listing
February 2019

Angiosarcoma with Synchronous Cutaneous and Small Bowel Involvement: A Report of a Rare Presentation.

Cureus 2018 Nov 28;10(11):e3650. Epub 2018 Nov 28.

Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Bismarck, USA.

Angiosarcomas are mesenchymal neoplasms of vascular origin that represent approximately 2% of soft tissue sarcomas. We discuss the case of a 75-year-old female who had presented with a purple nodular rash along the bilateral nasolabial folds. Upon further work-up, she was diagnosed with angiosarcoma, with the confirmed involvement of multi-focal sites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.3650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351118PMC
November 2018

Angiosarcoma and anaplastic carcinoma of the thyroid are two distinct entities: a morphologic, immunohistochemical, and genetic study.

Mod Pathol 2019 Feb 5. Epub 2019 Feb 5.

Pathology Unit, Arcispedale Santa Maria Nuova, Azienda USL-IRCCS, Reggio Emilia, Italy.

Angiosarcoma and anaplastic carcinoma are the most lethal neoplasms of the thyroid worldwide and share some similarities, which have led to a longstanding controversy on their etiopathological relationship. Thyroid angiosarcomas are characterized by vessel formation and an immunophenotype common to endothelial cells, while anaplastic carcinomas are partially or wholly composed of mesenchymal-like cells that have lost the morphologic and functional features of normal thyroid follicular cells. To investigate whether angiosarcomas represent the endothelial extreme of the differentiation spectrum of carcinomas or they are bona fide vascular neoplasms, we studied the clinico-morphologic and genetic characteristics of a series of 10 angiosarcomas and 22 anaplastic carcinomas. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41379-018-0199-z
Publisher Site
http://dx.doi.org/10.1038/s41379-018-0199-zDOI Listing
February 2019
3 Reads

A rare cause of recurrent hemopneumothorax.

Acta Clin Belg 2019 Feb 5:1-3. Epub 2019 Feb 5.

a Department of Pulmonology and Thoracic Oncology , Jessa Hospital , Hasselt , Belgium.

Background: Angiosarcoma is a rare and aggressive tumor of vascular endothelial origin. Pulmonary metastasis can lead to potential life-threatening complications, such as bleeding and pneumothorax.

Methods: We report on a 82-year-old male with major hemoptysis, recurrent hemopneumothorax and cystic lung lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17843286.2019.1578030DOI Listing
February 2019
1 Read

: a novel gene fusion in hepatic angiosarcoma.

Oncotarget 2019 Jan 4;10(2):245-251. Epub 2019 Jan 4.

Division of Hematology-Oncology, Lifespan Cancer Institute, Warren-Alpert Medical School of Brown University, Providence, RI, USA.

Hepatic angiosarcoma (HAS) is a rare and highly lethal malignancy with few effective systemic treatments. Relatively little is known about the genetic abnormalities that drive this disease. As a result, there has been minimal progress towards applying targeted therapies to the treatment of HAS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.26521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349438PMC
January 2019
1 Read

Clinical Outcomes and Prognostic Features of Angiosarcoma: Significance of Prior Radiation Therapy.

Clin Oncol (R Coll Radiol) 2019 Feb 1. Epub 2019 Feb 1.

Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, Missouri, USA. Electronic address:

Aims: Angiosarcoma is a rare and aggressive malignancy with a poor prognosis. There is limited literature describing prognostic factors and guidelines for treatment. We aim to describe outcomes in angiosarcoma, including the impact of patient-, tumour- and treatment-related factors on prognosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clon.2019.01.006DOI Listing
February 2019

The Molecular Diagnostics of Vascular Neoplasms.

Surg Pathol Clin 2019 Mar 4;12(1):35-49. Epub 2018 Dec 4.

Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic and Lerner Research Institute, Department of Pathology, 9500 Euclid Avenue L25, Cleveland, OH 44195, USA. Electronic address:

In this review, we provide an update of the recently discovered, diagnostically significant genetic aberrations harbored by a subset of vascular neoplasms. From benign (epithelioid hemangioma, spindle cell hemangioma), to intermediate (pseudomyogenic hemangioendothelioma), to malignant (epithelioid hemangioendothelioma, angiosarcoma), each neoplasm features a mutation or gene fusion that facilitates its diagnosis by immunohistochemistry and/or molecular ancillary testing. The identification of these genetic anomalies not only assists with the objective classification and diagnosis of these neoplasms, but also serves to help recognize potential therapeutic targets. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18759181183006
Publisher Site
http://dx.doi.org/10.1016/j.path.2018.10.002DOI Listing
March 2019
4 Reads

Hypoxia accelerates the progression of angiosarcoma through the regulation of angiosarcoma cells and tumor microenvironment.

J Dermatol Sci 2019 Jan 15. Epub 2019 Jan 15.

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

Background: Angiosarcoma is a rare malignant tumor with a poor prognosis. It is known that hypoxic condition activates tumor progression in several cancers. Additionally, hypoxic tumor microenvironment accelerates immune escape. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2019.01.005DOI Listing
January 2019

Intravascular papillary endothelial hyperplasia (Masson's hemangioma) of the face.

Arch Craniofac Surg 2019 Feb 1. Epub 2019 Feb 1.

Department of Pathology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.

Intravascular papillary endothelial hyperplasia or Masson's hemangioma is a rare vascular tumor. The reactive proliferation of endothelial cells in this disease mimics other benign or malignant vascular proliferation such as angiosarcoma or Kaposi's sarcoma. It is important to make an accurate distinction to avoid confusion with these malignant tumors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7181/acfs.2018.02208DOI Listing
February 2019

A Comparison of Outcomes and Prognostic Features for Radiation-Associated Angiosarcoma of the Breast and Other Radiation-Associated Sarcomas.

Int J Radiat Oncol Biol Phys 2019 Jan 28. Epub 2019 Jan 28.

Department of Pathology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

Purpose: Radiation-associated sarcomas (RAS) are considered to have a poor prognosis. While the incidence is anticipated to rise, contemporary data regarding predictors of outcomes are few. We performed a retrospective analysis to identify RAS prognostic factors, as well as subset analyses for radiation-associated angiosarcoma arising after treatment for breast cancer (RAAB) and other RAS subtypes (other-RAS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2019.01.082DOI Listing
January 2019

Persistent sciatic artery resembles a soft-tissue sarcoma in presentation.

BMJ Case Rep 2019 Jan 29;12(1). Epub 2019 Jan 29.

General Surgery, Dubai Hospital, Dubai, United Arab Emirates.

Persistent sciatic artery (PSA) is a rare vascular anomaly with estimated incidence of 0.03%-0.06%. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-227250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352791PMC
January 2019

[Epithelioid angiosarcoma arising in Schwannoma: report of a case].

Authors:
B He Y J Li

Zhonghua Bing Li Xue Za Zhi 2019 Feb;48(2):156-157

Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.02.019DOI Listing
February 2019

CT and MRI studies of hepatic angiosarcoma.

Clin Radiol 2019 Jan 24. Epub 2019 Jan 24.

Minimally Invasive Center, Tumour Hospital, Sun Yat-Sen University, Guangzhou, 510060, China. Electronic address:

Aim: To analyse the computed tomography (CT) and magnetic resonance imaging (MRI) manifestations of hepatic angiosarcoma.

Materials And Methods: Nineteen patients with hepatic angiosarcoma underwent preoperative abdominal unenhanced and contrast-enhanced CT (11 cases) or (eight cases) MRI.

Results: The results of a coagulation examination showed varying degrees of abnormalities in 12 (63. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.crad.2018.12.013DOI Listing
January 2019

Novel insights into endothelial cell malignancies.

Oncotarget 2018 Dec 25;9(101):37468-37470. Epub 2018 Dec 25.

Giovanna Tosato: Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.26516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331032PMC
December 2018

Combined hepatocellular-cholangiocarcinoma with angiosarcomatoid change: A case report with immunohistochemical study.

Pathol Int 2019 Feb 23;69(2):110-116. Epub 2019 Jan 23.

Department of Pathology, Toranomon Hospital, Tokyo, Japan.

Sarcomatoid combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare condition, with only 16 cases reported to date; however, there have been no reports of hepatic sarcomatoid carcinoma with angiosarcomatous features. Here, we report a rare case of cHCC-CCA with angiosarcomatoid changes in a 77-year-old man. The tumor was biphasic with malignant epithelial and mesenchymal components. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pin.12755DOI Listing
February 2019
1 Read

Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma.

Cancer Gene Ther 2019 Jan 23. Epub 2019 Jan 23.

Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.

Angiosarcoma is a deadly neoplasm of the vascular endothelium. Metastatic disease is often present at diagnosis, and 5-year survival is only 10-35%. Although there exist no immunocompetent mouse models of angiosarcoma with which to study immune-based approaches to therapy, angiosarcoma is a major killer of companion dogs, responsible for up to 2% of all canine deaths in some susceptible breeds or an estimated 120,000 per year in the US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41417-019-0080-3DOI Listing
January 2019

Laparoscopic access to the liver and application of laparoscopic microwave ablation in 2 dogs with liver neoplasia.

Vet Surg 2019 Jan 21. Epub 2019 Jan 21.

Department of Small Animal Clinical Sciences, Veterinary Medical Center, University of Florida, Gainesville, Florida.

Objective: To determine laparoscopic accessibility of liver lobes and access to the hilus and describe laparoscopic microwave ablation (LMWA) in 2 dogs with hepatic neoplasia.

Study Design: Experimental/descriptive case series.

Sample Population: Six canine cadavers and 2 clinical dogs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vsu.13153DOI Listing
January 2019
2 Reads

Dedifferentiated gastrointestinal stromal tumor: Recent advances.

Ann Diagn Pathol 2018 Dec 18. Epub 2018 Dec 18.

Department of Pathology and Genomic Medicine, Houston Methodist Hospital and Weill Medical College of Cornell University, Houston, TX 77030, USA. Electronic address:

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal lesions of the gastrointestinal tract. A small minority of GISTs exhibit morphologic and phenotypic changes and differentiate into an unusual phenotype through the process of dedifferentiation. Dedifferentiation can occur either de novo or after prolonged treatment with imatinib, a selective tyrosine kinase inhibitor. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anndiagpath.2018.12.005DOI Listing
December 2018
5 Reads

The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report.

Oncol Lett 2019 Jan 16;17(1):1253-1256. Epub 2018 Nov 16.

Department of Sense Organs, Sapienza University of Rome, Rome I-00186, Italy.

Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's tumour, is an unusual vascular lesion characterized by the proliferation of endothelial cells. The principal significance of IPEH is its clinical and radiological resemblance to angiosarcoma, resulting in a potential misdiagnosis and overtreatment. The aim of the present study is to report a rare case of IPEH of the right maxillary sinus, focusing on the radiological and histopathological features of the neoplasm and their role in the differential diagnosis with angiosarcoma. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/ol.2018.9717
Publisher Site
http://dx.doi.org/10.3892/ol.2018.9717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313067PMC
January 2019
3 Reads

Primary Cutaneous Angiosarcoma of the Eyelid: A Diagnostic and Therapeutic Challenge.

Ocul Oncol Pathol 2018 Jun 12;4(4):230-235. Epub 2018 Jan 12.

Department of Ophthalmic Pathology, Thomas Jefferson University, Philadelphia, PA, USA.

Primary cutaneous angiosarcoma is a rare vasoformative malignant neoplasm that can present a diagnostic and therapeutic challenge. We describe a 76-year-old Caucasian man with right upper eyelid swelling and nodularity, initially suspected clinically to represent either ocular adnexal lymphoma or basal cell carcinoma. Incisional biopsy and wide resection of the mass with frozen section control of margins were interpreted as compatible with hobnail (Dabska-retiform) hemangioendothelioma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000485427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322085PMC
June 2018
1 Read

[A case of spontaneous rupture of primary hepatic angiosarcoma].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Nov;43(11):1276-1280

Department of General Practice, First Affiliated Hospital of Jilin University, Changchun 130021, China.

Primary hepatic angiosarcoma (PHA) is a rare disease with high malignancy. Due to the low incidence, atypical clinical symptoms and signs, it is often misdiagnosed, which results in missing timely treatment, and subsequently influencing the therapeutic effect and prognosis. A case of hepatic angiosarcoma with acute abdominal pain as the first symptom was reported in First Hospital affiliated to Jilin University in Match, 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11817/j.issn.1672-7347.2018.11.019DOI Listing
November 2018
1 Read

Surgical therapy of primary hepatic angiosarcoma.

BMC Surg 2019 Jan 10;19(1). Epub 2019 Jan 10.

Department of General, Visceral and Transplantation Surgery, University Hospital of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

Background: Primary hepatic angiosarcoma (PHA) is a rare tumor entity. Radical surgical resection is currently considered the best treatment choice. The aim of this analysis is to report our experience with surgery for PHA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12893-018-0465-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329081PMC
January 2019
2 Reads

Splenic Angiosarcoma Diagnosed on Bone Marrow Biopsy: Case Report and Literature Review.

Radiol Case Rep 2019 Mar 4;14(3):390-395. Epub 2019 Jan 4.

Department of Radiology, Northwell Health System, Lenox Hill Hospital, 100 East 77th St, New York, NY 10075 USA.

Primary splenic angiosarcoma carries a poor prognosis and is among the rarest forms of malignancy. An overwhelming majority of patients with splenic angiosarcoma will develop metastases. However, osseous metastatic disease is rare. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radcr.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321865PMC

Primary Common Iliac Artery Angiosarcoma With Multiple Bone Metastases Revealed by Dual-Time Point FDG PET/CT Imaging.

Clin Nucl Med 2019 Mar;44(3):232-233

From the Departments of Nuclear Medicine and.

Iliac artery angiosarcoma is rare, and bone metastasis as its presenting initial symptom is extremely rare. A 67-year-old man with a history of low back pain presented with multiple MRI-identified lumbar and sacrum lesions highly suggestive of bone metastasis. On subsequent PET/CT scan, in addition to multiple vertebrae and pelvis hypermetabolism, a lesion with intense focal uptake was discovered within the lumen of left common iliac artery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000002435DOI Listing
March 2019
5 Reads

Malignant peripheral nerve sheath tumor (MPNST) arising from angiosarcoma: a rare case report.

Oral Maxillofac Surg 2019 Mar 7;23(1):109-112. Epub 2019 Jan 7.

Department of Oral and Maxillofacial Surgery "Theagenio" Cancer Hospital (Former), "Theagenio" Cancer Hospital, Thessaloniki, Greece.

Purpose: An extremely rare case of divergent differentiation of a cutaneous angiosarcoma to a malignant peripheral nerve sheath tumor (MPNST) is presented.

Methods: A 62-year-old male patient presented with an angiosarcoma of the left buccal region, which was excised with wide surgical margins. Four months after the operation, the tumor recurred locally as a MPNST. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10006-018-0740-8DOI Listing
March 2019
1 Read

Stereotactic Body Radiation Therapy for the Treatment of Primary Cardiac Angiosarcoma Causing Hemodynamic Instability.

Pract Radiat Oncol 2019 01;9(1):5-8

Department of Radiation Oncology, Washington University School of Medicine in Saint Louis, Saint Louis, Missouri. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2018.07.004DOI Listing
January 2019
1 Read

Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions.

PLoS One 2019 2;14(1):e0210297. Epub 2019 Jan 2.

Department of Veterinary Clinical Medicine, University of Illinois, Urbana, IL, United States of America.

Background: Canine hemangiosarcoma (cHSA) is a highly metastatic mesenchymal cancer that disseminates by hematogenous and direct implantation routes. Therapies for cHSA are generally ineffective, in part due to advanced clinical disease stage at the time of diagnosis. The validation of conventional molecular methods for detecting novel biomarkers preferentially expressed by cHSA could lead to more timely diagnosis, earlier therapeutic interventions, and improved outcomes. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210297PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314605PMC
January 2019
1 Read

A case report of cutaneous angiosarcoma combined treated by photodynamic therapy with chemotherapy and surgery.

Photodiagnosis Photodyn Ther 2018 Dec 28. Epub 2018 Dec 28.

The Department of Dermatology, Xiangya Hospital, Central South University, 87, Xiangya Road, Changsha, 41008, Hunan, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2018.12.012DOI Listing
December 2018
1 Read

Hepatic angiosarcoma in a patient with liver cirrhosis.

Gastroenterol Hepatol 2018 Dec 19. Epub 2018 Dec 19.

Gastroenterology and Hepatology Department, Hospital Universitario Ramón y Cajal, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gastrohep.2018.10.011DOI Listing
December 2018
1 Read

Primary angiosarcoma of the femoral artery in patient with kidney and liver polycystosis and multiple arterial aneurysms: report of the case and review of the literature.

Cardiovasc Pathol 2018 Nov 30;39:8-11. Epub 2018 Nov 30.

Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, Prague, 5, 150 06, Czech Republic.

The association between kidney and liver polycystosis and arterial aneurysms is well documented. However, it remains unclear whether these patients are at increased risk of malignant transformation. In this article, we describe a case of a primary angiosarcoma of the femoral artery with metastatic spread into the lungs and hilar lymph node arising in a 74-year-old man with kidney and liver polycystosis and multiple arterial aneurysms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carpath.2018.11.001DOI Listing
November 2018
1 Read

Primary cardiac sarcomas: A multi-national retrospective review.

Cancer Med 2019 Jan 21;8(1):104-110. Epub 2018 Dec 21.

Sarcoma Department, Mount Sinai Hospital, Toronto, Ontario, Canada.

Background: Primary cardiac sarcoma (PCS) is a rare but often fatal disease. The current study aimed to analyze the impact of baseline demographics, local and systemic therapies in a contemporary cohort.

Methods: Clinical records of PCS across six institutions in three continents were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.1897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346258PMC
January 2019
2 Reads

Evaluation of hepatic tumor portal perfusion using mesenteric angiography: A pilot study in 5 dogs.

J Vet Intern Med 2018 Dec 18. Epub 2018 Dec 18.

Lamb Statistical Consulting, West St. Paul, Minnesota.

Background: Mesenteric angiography is a sensitive method for visualizing portal perfusion in the dog.

Objectives: To evaluate hepatic portal perfusion in dogs with incompletely resectable hepatic tumors using mesenteric angiography.

Animals: Five client-owned dogs with incompletely resectable hepatic tumors evaluated with mesenteric angiography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jvim.15395DOI Listing
December 2018
4 Reads

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.

Nat Commun 2018 12 17;9(1):5357. Epub 2018 Dec 17.

Laboratory for Cell Polarity and Organogenesis, Max Planck Institute for Heart and Lung Research, 61231, Bad Nauheim, Germany.

Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, suppression of aPKCλ impairs proliferation despite hyperactivated mitogenic signaling. Read More

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-07739-0
Publisher Site
http://dx.doi.org/10.1038/s41467-018-07739-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297234PMC
December 2018
9 Reads

Angiosarcoma originating in the anterior mediastinum: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13459

Department of Pathology, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, China.

Rationale: Angiosarcomas are malignant vascular tumors, and angiosarcoma occurring in the anterior mediastinum is rare. Here we report a case of angiosarcoma that originated in the anterior mediastinum treated with surgery, followed by radiotherapy and synchronous chemotherapy.

Patient Concerns: A 56-year-old female was admitted to our hospital with chest pain for 3 days. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00005792-201812140-0003
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000013459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319824PMC
December 2018
6 Reads

Radiotherapy-associated intra-abdominal angiosarcoma after prostatic adenocarcinoma: Case reports.

Mol Clin Oncol 2018 Dec 5;9(6):592-596. Epub 2018 Oct 5.

Pathology Service, University Hospital of Saint Joan, Faculty of Medicine, IISPV, 'Rovira i Virgili' University, Reus, 43204 Tarragona, Spain.

Angiosarcoma is a rare soft tissue neoplasm, which accounts for <1% of all soft tissue tumours. It has been previously reported that the incidence rate of angiosarcomas increases following radiotherapy. The present study reports two cases of intra-abdominal angiosarcoma associated with previous radiotherapy treatment. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/mco.2018.1738
Publisher Site
http://dx.doi.org/10.3892/mco.2018.1738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256091PMC
December 2018
8 Reads