8,673 results match your criteria Angiosarcoma
J Dtsch Dermatol Ges 2018 Dec 6. Epub 2018 Dec 6.
Department of Dermatology, Venereology and Allergology, Leipzig University Medical Center, Leipzig, Germany.
Br J Dermatol 2018 Dec;179(6):1246
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
J Vet Intern Med 2018 Nov 7;32(6):2311. Epub 2018 Oct 7.
Braz J Cardiovasc Surg 2018 Sep-Oct;33(5):525-527
Department of Cardiovascular Surgery, Kartal Kosuyolu Heart Research and Training Hospital, Istanbul, Turkey.
Primary angiosarcoma is a rare clinical entity, it's typically located within the right atrium and known to be rapidly fatal. A 37-year-old female was presented with a history of recurrent facial paralysis and left hemiparesis. A cranial mass was identified at cranial magnetic resonance imaging and she underwent neurosurgery operation. Read More
Int J Gynecol Pathol 2018 Dec 3. Epub 2018 Dec 3.
Department of Pathology, Royal Gwent Hospital, Newport (V.I.S., I.W.T.) Department of Pathology, University Hospital of Wales, Cardiff (G.L.R.) Department of Musculoskeletal Pathology, Royal Orthopaedic Hospital, Birmingham (V.P.S.) Department of Pathology, Belfast Health and Social Care Trust, Belfast (W.G.M.), UK.
Angiosarcomas of the female genital tract are rare and primary angiosarcoma of the cervix is extremely rare with only one prior case report. We report a case of a primary cervical angiosarcoma in a 43-yr-old woman who presented with heavy vaginal bleeding. Cervical biopsy and subsequent radical hysterectomy showed a malignant vascular tumor which was composed of spindled and epithelioid cells and formed abortive vascular channels. Read More
Breast Cancer Res Treat 2018 Dec 3. Epub 2018 Dec 3.
Division of Pathology, Singapore General Hospital, Level 7, Diagnostics Tower, Academia, 20 College Road, Singapore, 169856, Singapore.
Purpose: We aimed to investigate the genomic profile of breast sarcomas (BS) and compare with that of malignant phyllodes tumours (MPT).
Methods: DNA was extracted from formalin-fixed, paraffin-embedded (FFPE) specimens from 17 cases of BS diagnosed at Singapore General Hospital from January 1991 to December 2014. Targeted deep sequencing and copy number variation (CNV) analysis on 16 genes, which included recurrently mutated genes in phyllodes tumours and genes associated with breast cancer, were performed on these samples. Read More
BMC Cancer 2018 Dec 3;18(1):1200. Epub 2018 Dec 3.
Department of Medical Oncology and Clinical Pharmacology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
Background: Pazopanib is a tyrosine kinase inhibitor indicated for the treatment of renal cell carcinoma and soft tissue sarcoma. Despite the high inter-patient variability in pharmacokinetic exposure, pazopanib is administered at a fixed dose of 800 mg once daily (QD). Pharmacokinetic exposure is linked to both efficacy and toxicity. Read More
Ann Vasc Surg 2018 Nov 27. Epub 2018 Nov 27.
Department of Vascular Surgery, School of Medicine, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.
Angiosarcomas developing in non-functioning arteriovenous fistulae in renal transplant recipients are quite rare clinical entities with very poor prognosis. Herein we present a 60-year-old male who developed an angiosarcoma in a thrombosed radiocephalic fistula six years after renal transplantation. The patient presented with pain and swelling at the site of a previously asymptomatic fistula. Read More
Hematol Oncol Clin North Am 2019 Feb;33(1):87-101
Department of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA; Cutaneous Oncology Program, Dana Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:
Cutaneous sarcomas are rare malignancies that may present with a variety of clinical manifestations. This article focuses on 4 of the most common cutaneous sarcomas (Kaposi sarcoma, cutaneous angiosarcoma, dermatofibrosarcoma protuberans, and cutaneous leiomyosarcoma) and reviews clinical, diagnostic, and therapeutic aspects of these rare skin malignancies. Read More
Cutis 2018 Oct;102(4):E8-E11
Wright State University Boonshoft School of Medicine, Dayton, and Jobst Vascular Institute/ProMedica Health System Toledo Hospital, Ohio, USA.
Angiosarcoma is a vascular malignancy that can affect various anatomic sites. Although rare, cutaneous angiosarcoma is the most common clinical manifestation, accounting for approximately 50% to 60% of cases. Cutaneous angiosarcoma typically is known to occur in 3 settings: (1) idiopathic, (2) following radiation treatment, and (3) in the setting of chronic lymphedema following mastectomy (known as Stewart-Treves syndrome). Read More
Clin Breast Cancer 2018 Dec 29;18(6):498-503. Epub 2018 Sep 29.
Department of Radiation Medicine, Oregon Health and Science University, Portland, OR. Electronic address:
Introduction: Primary breast angiosarcoma is a rare malignancy with no clinical trials to guide management. The current use of surgery, chemotherapy, and radiotherapy among North American oncologists is unknown.
Patients And Methods: An institutional review board-approved anonymous electronic survey was distributed to 9660 practicing North American radiation and medical oncologists. Read More
Am J Ind Med 2018 Nov 25. Epub 2018 Nov 25.
Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
Background: Occupational exposure to vinyl chloride monomer (VCM) has been established as a cause of hepatocellular carcinoma (HCC) and liver angiosarcoma (ASL). However, some controversy remains due to conflicting results on liver cirrhosis, and to evidence on HCC based on few confirmed cases. The aim of the study is to clarify the association between VCM exposure and mortality from liver diseases. Read More
Medicine (Baltimore) 2018 Nov;97(47):e13321
Hematology Division, Massachusetts General Hospital, Boston, MA.
Rationale: Hepatic angiosarcoma is a rare endothelial cell tumor that may lead to concurrent consumptive coagulopathies including disseminated intravascular coagulation (DIC). This report details a multifaceted approach to managing DIC in a patient with advanced-stage hepatic angiosarcoma, which continued to progress after a brief response to taxane-based chemotherapy.
Patient Concerns: A 55-year-old man with a recent history of hemorrhoids and hemarthroses presented with acute rectal bleeding. Read More
Oncoscience 2018 Sep 11;5(9-10):264-268. Epub 2018 Oct 11.
Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Angiosarcoma is the most common malignant cardiac tumor. Cardiac angiosarcoma is a highly lethal neoplasm that is largely resistant to conventional anti-cancer therapy. Mean survival of patients with cardiac angiosarcoma is only 4 months, and almost all patients will succumb to the disease within 1 year. Read More
Ann Surg Oncol 2018 Nov 19. Epub 2018 Nov 19.
Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Background: Hepatic angiosarcoma is a rare primary liver tumor. The aim of this current study was to evaluate the presentation and treatment outcomes in a modern cohort.
Methods: This was a retrospective, multi-institutional, observational study of patients with histopathologic diagnoses of primary hepatic angiosarcoma from four institutions. Read More
J Thorac Cardiovasc Surg 2018 Dec 6;156(6):2194-2203. Epub 2018 Jun 6.
Department of Medicine (Oncology), Stanford University School of Medicine, Stanford, Calif. Electronic address:
Objective: Primary cardiac sarcomas (PCS) are extremely rare, portend a very poor prognosis, and have limited outcomes data to direct management. This study evaluated the impact of postoperative chemotherapy and/or radiotherapy on survival for PCS.
Methods: A retrospective chart review was conducted of 12 patients diagnosed with and who underwent resection for PCS at a single institution between 2000 and 2016. Read More
Am Surg 2017 Dec;83(12):e476-e477
Rush University Medical Center, Chicago, Illinois, USA.
Surg Pathol Clin 2018 Dec;11(4):825-836
Department of Pathology, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, Weinberg 2242, 401 North Broadway, Baltimore, MD 21231-2410, USA; Department of Urology, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, Weinberg 2242, 401 North Broadway, Baltimore, MD 21231-2410, USA; Department of Oncology, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, Weinberg 2242, 401 North Broadway, Baltimore, MD 21231-2410, USA. Electronic address:
Certain tumors are more difficult to recognize when they present in an unusual location. Within the urinary tract, primary melanomas, carcinoid tumors, or epithelioid angiosarcoma could present diagnostic challenges due to their infrequent occurrence. This article emphasizes the clinical and histopathologic features of these entities and their differential diagnoses including the immunophenotype and their prognoses. Read More
Cesk Patol 2018 ;54(3):143-146
Diagnosing accessory breast tissue in a male patient is difficult when the condition is unilateral, and there is no areola or nipple. Pseudoangiomatous hyperplasia of the mammary stroma is an uncommon benign mesenchymal proliferation that may mimic low-grade angiosarcoma. We report herein an example of tumoriform pseudoangiomatous hyperplasia of the stroma arising in the accessory breast tissue of a 38-year-old man. Read More
Cureus 2018 Sep 11;10(9):e3283. Epub 2018 Sep 11.
Medicine/Gastroenterology and Hepatology, Hartford Hospital, Hartford, USA.
Hepatic angiosarcoma (HA) accounts for 2% of primary liver tumors. Though rare, it is exceptionally deadly. The initial presentation of HA is nonspecific and no tumor markers have been associated with it. Read More
Surg Case Rep 2018 Nov 13;4(1):132. Epub 2018 Nov 13.
Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital, 37-1 Uearata, Kagoshima, 890-0055, Japan.
Background: The incidence of radiation-associated angiosarcoma (RAA) of the breast has been increasing, and its prognosis is reportedly poor. It is important to remove tumor tissues completely to prevent recurrence.
Case Presentation: We report two cases of patients with RAA of the breast. Read More
Can Vet J 2018 Nov;59(11):1209-1212
Small Animal Hospital, Texas A&M Veterinary Medical Teaching Hospital, College of Veterinary Medicine & Biomedical Sciences, 402 Raymond Stotzer Parkway, College Station, Texas 77845, USA.
A 7-year-old castrated male Maltese dog was presented for increased respiratory sounds, inability to bark, dysphagia, and hyporexia. Radiographs revealed an ovoid, opaque mass in the caudal nasopharynx. An airway examination and computed tomography scan were followed by endoscopic polypoidectomy. Read More
Thorac Cancer 2018 Nov 8. Epub 2018 Nov 8.
Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan.
Herein, we report a case of an angiosarcoma in a mediastinal non-seminomatous germ cell tumor that exhibited growing teratoma syndrome during chemotherapy. A 26-year-old man presented with a giant anterior mediastinal mass, which was diagnosed as a non-seminomatous germ cell tumor. The patient was administered three cycles of chemotherapy (bleomycin, etoposide, and cisplatin), but the mass grew despite normalization of tumor markers. Read More
Surg Case Rep 2018 Nov 7;4(1):131. Epub 2018 Nov 7.
Department of Breast Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, chikusa-ku, Nagoya, Aichi, 〒464-8681, Japan.
Background: Radiation-associated angiosarcoma (RAAS) is a rare subtype of secondary angiosarcoma that is characterized by rapid proliferation and extensive tissue infiltration. Although various treatments for RAAS (such as surgery, chemotherapy, and radiation therapy) have been reported, there is no consensus as to which approach is the best.
Case Presentation: A 76-year-old woman presented with right breast cancer (T1N0M0, stage I) 9 years ago. Read More
J Public Health Policy 2018 Nov;39(4):463-540
Mailman School of Public Health, Center for the History & Ethics of Public Health, Columbia University, 722 West 168th Street Room 935, New York, NY, 10032, USA.
For the past three decades, we have written on the history of occupational and environmental health, authoring books and articles on lead poisoning, silicosis, asbestosis, and angiosarcoma of the liver, among other diseases. One book, Deceit and Denial, focused specifically on the chemical and lead industries. Because of the rarity of historians who study this history, we have been asked to testify on behalf of workers who allege harm from these industrial materials and by state, county, and local governments who seek redress for environmental damages and funds to prevent future harm to children. Read More
SAGE Open Med Case Rep 2018 30;6:2050313X18796343. Epub 2018 Oct 30.
Division of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada.
Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart-Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. Read More
Eur J Dermatol 2018 Aug;28(4):557-558
Department of Plastic and Reconstructive Surgery, Division of Vascular Anomalies, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine. Shanghai China.
Rev Esp Med Nucl Imagen Mol 2018 Oct 30. Epub 2018 Oct 30.
Servicio de Medicina Nuclear-PET, IDI Bellvitge, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, España.
Primary cardiac or pericardial tumors are infrequent, metastatic involvement being more common. Cardiac angiosarcoma is a rare primary malignant tumor of mesenchymal origin. It entails a poor prognosis mostly due to frequent metastases at the time of diagnosis, as well as low response to onco-specific treatments. Read More
Clin Nucl Med 2018 Oct 27. Epub 2018 Oct 27.
Department of Oncology, Institut Curie, PSL Research University, Paris, France.
Breast angiosarcoma is a rare and aggressive tumor. The role of F-FDG PET/CT in breast angiosarcoma is poorly known. We report a series of 13 lesions in 11 patients with histologically proven primary or secondary breast angiosarcoma who underwent FDG PET/CT at the initial assessment in our institution. Read More
Radiol Bras 2018 Sep-Oct;51(5):281-286
Department of Radiology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, Portugal.
Objective: To characterize a population of patients with radiation-induced angiosarcoma (RIAS) of the breast treated at an oncology center, focusing mainly on the imaging features, although also on the clinical presentation, diagnosis, and management.
Materials And Methods: We performed a retrospective review of patients with histologically proven angiosarcoma of the breast or chest wall, all of whom received radiotherapy, after conservative or radical breast surgery, between 2000 and 2015.
Results: Eleven patients met the inclusion criteria. Read More
BJR Case Rep 2018 1;4(2):20170022. Epub 2017 Nov 1.
Department of Diagnostic Radiology, Institute of Biomedical and Health Sciences,Hiroshima University, Minami-ku, Hiroshima, Japan.
Anastomosing haemangioma is a rare subtype of capillary haemangioma. Pathologically, anastomosing haemangioma presents with anastomosing sinusoidal capillary-sized vessels in an architecture reminiscent of the splenic parenchyma. Its anastomosing architecture pathologically can lead to concern for angiosarcoma. Read More
Cir Cir 2018 ;86(6):566-569
Department of Surgery Division of Surgical Oncology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Angiosarcomas are neoplasms of blood or lymphatic vessels with aggressive behavior. We report the coexistence of this malignancy within soft tissue of the breast in a 49-year-old woman who was diagnosed with Klippel-Trenaunay-Weber syndrome (KTW-S) during childhood. The patient has no previous history of radiation therapy on the chest and does not have any known risk factor for developing angiosarcoma, except for her congenital disease. Read More
J Comp Pathol 2018 Oct 20;164:37-43. Epub 2018 Sep 20.
Graduate Institute of Veterinary Pathobiology, Taichung, Taiwan, Republic of China; Animal Disease Diagnostic Center, National Chung Hsing University, Taichung, Taiwan, Republic of China. Electronic address:
Fifteen splenic biopsy specimens from a total of 212 biopsy specimens and necropsy cases of domestic hamsters (Phodopus spp.) from the Division of Wild (Exotic) Animal Medicine, Veterinary Medical Teaching Hospital, National Chung Hsing University, Taiwan, collected between 2010 and 2017, were studied retrospectively. The incidence of lesions in the spleen was 7. Read More
Head Neck Pathol 2018 Oct 24. Epub 2018 Oct 24.
Division of Oral and Maxillofacial Pathology, NewYork-Presbyterian/Columbia University Irving Medical Center, 630 West 168th Street PH15-1562W, New York, NY, 10032, USA.
Head and neck angiosarcomas (HN-AS) are rare malignancies with a poor prognosis relative to other soft tissue sarcomas. To date, the HN-AS literature has been limited to short reports and single-institution experiences. This study evaluated patients registered with the Surveillance, Epidemiology, and End Results (SEER) program who had been diagnosed with a primary HN-AS. Read More
Ann Oncol 2018 Oct 24. Epub 2018 Oct 24.
Clinical Department, TRACON Pharmaceuticals, San Diego, CA, USA.
Background: Major challenges in clinical trials of ultra orphan oncology diseases include limited patient availability and paucity of reliable prior data for estimating the treatment effect and, therefore, determining optimal sample size. Angiosarcoma (AS), a particularly aggressive form of soft tissue sarcoma with an incidence of about 2,000 cases per year in the United States and Europe is poorly addressed by current systemic therapies. Pazopanib, an inhibitor of vascular endothelial growth factor receptor (VEGFR) is approved for the treatment of AS, with modest benefit. Read More
J Community Hosp Intern Med Perspect 2018 15;8(5):300-302. Epub 2018 Oct 15.
Gilchrist Baltimore, Greater Baltimore Medical Center, Baltimore, MD, USA.
Cutaneous angiosarcoma (CA) is a rare form of cancer with limited treatment options and has a very severe prognosis. In this case report, a differential diagnosis, ranging from infection and neoplasia to autoimmune disease, was attributed to recurrent cellulitis centered on a purple lesion. The continuous pursuit of a diagnosis and treatment plan had to be tailored in accordance with patient goals of care. Read More
Circ Heart Fail 2018 Oct;11(10):e005342
Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Y.L., B.W., L.Z., Y.Y., J.W., Q.L., M.X.).
Plast Reconstr Surg Glob Open 2018 Sep 5;6(9):e1938. Epub 2018 Sep 5.
Division of Plastic Surgery, Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, Mass.
Background: Radiation-associated angiosarcoma (RAAS) of the breast is a rare complication following breast irradiation with high rates of recurrence and death. To improve survival, we have advocated for an extra-radical resection where the entire irradiated skin and subcutaneous tissue is excised. This results in very large chest defects for which we describe our reconstructive experience. Read More
Oncology 2018 Oct 18:1-11. Epub 2018 Oct 18.
Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Background: We retrospectively investigated the treatment outcomes of second-line treatment with pazopanib or gemcitabine/docetaxel in patients with advanced soft tissue sarcoma (STS).
Methods: Ninety-one patients who were treated with pazopanib or gemcitabine/docetaxel for advanced STS between 1995 and 2015 were analyzed.
Results: Forty-six and 45 patients received pazopanib and gemcitabine/docetaxel, respectively. Read More
Front Endocrinol (Lausanne) 2018 1;9:577. Epub 2018 Oct 1.
Endocrinology of Aging Unit, Department of Medicine and Surgery, University of Parma, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Angiosarcoma (AS) of the thyroid is a rare and aggressive tumor. Its incidence is higher in iodine-deficient areas but cases unrelated to endemic goiter have been reported. We describe a case of a 63-year-old Italian man living in a non-iodine-deficient area, with no previous diagnosis of thyroid disease with a history of radiation exposure. Read More
BMC Cancer 2018 Oct 16;18(1):978. Epub 2018 Oct 16.
Postgraduate Program in Health Sciences, Federal University of Piaui, Teresina, Brazil.
Background: Sarcomas account for less than 1% of primary breast cancers, and breast angiosarcomas are responsible for only 0.05% of all breast malignancies. The male breast has the same potential for malignant transformation as the female breast. Read More
J Surg Case Rep 2018 Oct 11;2018(10):rjy273. Epub 2018 Oct 11.
Division of Surgical Oncology, Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA.
Angiosarcomas are a rare subtype of soft-tissue sarcomas originating from the vascular endothelium. Both retroperitoneal and omental angiosarcomas tend to be aggressive and rapidly fatal if not amenable to early intervention. In this report, we describe an unusual case of high-grade angiosarcoma with cytology-negative hemorrhagic ascites and diffuse omental invasion. Read More
J Belg Soc Radiol 2018 Oct 1;102(1):60. Epub 2018 Oct 1.
AZ Delta Roeselare, BE.
Radiol Case Rep 2019 Jan 4;14(1):28-29. Epub 2018 Oct 4.
Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
BMC Cancer 2018 Oct 11;18(1):963. Epub 2018 Oct 11.
Direction of Research and Innovation, Centre Oscar Lambret, 3 rue Combemale, 59020, Lille cedex, France.
Background: We report here a correlation analysis conducted along with a phase II trial assessing bevacizumab in combination with weekly paclitaxel.
Methods: Circulating pro/anti-angiogenic factors were assessed on day 1 (D1) and day 8 (D8). The prognostic value for progression-free survival (PFS) was evaluated using a Cox model with biomarkers as continuous variables. Read More
Indian J Pathol Microbiol 2018 Oct-Dec;61(4):577-579
Department of Histopathology, Apollo Cancer Institutes, Chennai, Tamil Nadu, India.
Pure mesenchymal sarcomas and phyllodes tumor with sarcomatous differentiation of the breast are rare tumors. Primary breast sarcomas are a heterogenous group of neoplasms which include malignant fibrous histiocytoma, fibrosarcoma, angiosarcoma, leiomyosarcoma, osteosarcoma, rhabdomyosarcoma, and liposarcoma. Sarcomatous differentiation in phyllodes tumor is seen in the form of angiosarcoma, chondrosarcoma, leiomyosarcoma, osteosarcoma, rhabdomyosarcoma, and liposarcoma. Read More
Urol Case Rep 2018 Nov 19;21:116-118. Epub 2018 Sep 19.
Department of Urology, Medical College of Wisconsin, Milwaukee, WI, USA.