3,572 results match your criteria Angiomyolipoma Kidney
Curr Med Res Opin 2018 Dec 14:1-18. Epub 2018 Dec 14.
d LeBonheur Children's Hospital and St. Jude Children's Research Hospital.
Objective: Everolimus is the only FDA approved drug to treat renal angiomyolipoma or subependymal giant-cell astrocytomas (SEGA) in tuberous sclerosis complex (TSC). Potential differences exist between patients with commercial and Medicaid insurance on everolimus use, however, there is limited information from the real-world. This study compared compliance and persistence of everolimus between commercial and Medicaid patients using the US claims data. Read More
J Rural Med 2018 Nov 29;13(2):181-184. Epub 2018 Nov 29.
Department of Urology, JA Toride Medical Center, Japan.
Renal angiomyolipoma without local invasion is usually considered benign entity, however, it may extend into the renal vein or the inferior vena cava. Renal angiomyolipoma with venous extension should be treated; however, surgical complications such as iatrogenic pulmonary fat embolism remain a serious concern. We present a case of a 66-year-old Japanese woman without tuberous sclerosis in whom a right-sided renal tumor was incidentally detected on ultrasonography during a health check-up. Read More
Klin Onkol 2018 ;31(6):448-452
Background: Epithelioid angiomyolipoma (EAML) of the kidney, in contrast to classic benign renal angiomyolipoma, is a rare mesenchymal neoplasm with malignant potential. Represent-ing a member of the perivascular epithelioid cells (PEComa) tumor family aris-ing from the perivascular epithelioid cells, its accurate dia-gnosis and therapeutic approach remains challenging.
Methods: We report a case of a patient with malignant EAML, initially treated as renal cell carcinoma (RCC) at our institution. Read More
Eur Radiol 2018 Dec 12. Epub 2018 Dec 12.
Department of Radiology, School of Medicine, Juntendo University, Tokyo, Japan.
Objectives: To identify factors predicting the presence of extrarenal feeders to renal angiomyolipomas (AMLs) METHODS: This is a retrospective study of 44 patients with 58 renal AMLs embolized in our department. Arteriography obtained during embolization and CT angiography obtained before and after embolization were reviewed to characterize AMLs with and without extrarenal feeders. Tumor characteristics were compared between the two groups. Read More
BMC Ophthalmol 2018 Dec 12;18(1):319. Epub 2018 Dec 12.
Department of Ophthalmology, the Ninth People's Hospital, Shanghai Jiao Tong University, No 639 ZhiZaoJu Road, Shanghai, 200011, China.
Background: Spectral domain optical coherence tomography (SD-OCT) is proposed as a way of predicting the development and likelihood of retinal astrocytic hamartoma (RAH) in tuberous sclerosis complex (TSC) in elderly patients.
Case Presentation: This report describes a case of RAH in TSC in an elderly patient. The patient was a 62-year-old woman and experienced pain in the lower left abdomen for two years. Read More
Radiol Med 2018 Dec 11. Epub 2018 Dec 11.
Diagnostic and Interventional Radiology Department, ASST Santi Paolo e Carlo, San Paolo Hospital, University of Milan, Via A di Rudinì 8, 20142, Milan, Italy.
Aim: To evaluate efficacy, safety and quality of life of the patients with renal angiomyolipomas (AMLs) associated with tuberous sclerosis complex (TSC) treated with percutaneous microwave ablation (MWA).
Materials And Methods: Nine patients (7 females and 2 males; mean age 27.6 years, range 23-34), with 10 renal AMLs with a mean size of 6. Read More
Zhonghua Yi Xue Za Zhi 2018 Dec;98(45):3701-3704
Department of X-ray, the Affiliated Chinese Medical Hospital of Southwest Medical University, Luzhou 646300, China.
To investigate whether MRI findings can differentiate renal epithelioid angiomyolipoma (EAML) from renal no-epithelioid (typical) angiomyolipoma. A total of 44 patients were collected from General Hospital of PLA.These cases were obtained from January 2009 to June 2015. Read More
Respirol Case Rep 2019 Feb 28;7(2):e00389. Epub 2018 Nov 28.
Department of Respiratory Medicine Cork University Hospital Ireland.
A 45-year-old lady presented acutely with pleuritic chest pain, haemoptysis, and dyspnoea. Her background was significant for a 1.4 cm renal angiomyolipoma, and she was an ex-smoker without any relevant family history. Read More
Pol Arch Intern Med 2018 Nov 20. Epub 2018 Nov 20.
J Investig Med 2018 Nov 18. Epub 2018 Nov 18.
School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Tuberous sclerosis complex (TSC) is a rare disease that causes multisystem benign neoplasm, induced by dysregulation of the mammalian target of the rapamycin pathway (mTOR). This study aimed to examine the effects of continuous low-dose everolimus, a potent and selective inhibitor of mTOR, on the treatment of TSC-associated renal angiomyolipoma (AML). Between July 2013 and August 2017, 11 patients with TSC-AML were enrolled for an everolimus therapy protocol. Read More
PLoS One 2018 15;13(11):e0204646. Epub 2018 Nov 15.
Groupe d'analyse, Ltée, Montréal, QC, Canada.
Objective: To compare kidney size (used as proxy for total renal angiomyolipoma [rAML] size) and kidney function outcomes between patients with tuberous sclerosis complex (TSC) and rAML treated and not treated with everolimus.
Methods: Medical charts of adults with TSC-associated rAML followed at a specialty medical center in the Netherlands (1990-2015). Included patients treated with everolimus (n = 33, of which 27 were included in the kidney size analyses and 27 in the kidney function analyses [21 patients in both]; index date = everolimus initiation) and non-treated patients (n = 39, of which 29 were included in the kidney size analyses and 33 in the kidney function analyses [23 patients in both]; index date = one date among all dates with outcome measurement). Read More
World J Clin Oncol 2018 Nov;9(7):162-166
Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi 110095, India.
A 42-years-old lady, presented with a large retroperitoneal mass which was preoperatively diagnosed as a retroperitoneal liposarcoma following an image guided core biopsy. She underwent a margin-negative resection of the retroperitoneal mass (multi visceral resection - enbloc excision of the retroperitoneal mass with a left nephrectomy and a segmental descending colectomy). The final histopathological examination of the resected specimen confirmed an exophytic renal angiomyolipoma (AML) which was extending into the retroperitoneum. Read More
J Nephrol 2018 Nov 7. Epub 2018 Nov 7.
Laboratory of Experimental Nephrology, Renal Division, Dipartimento di Scienze della Salute, San Paolo Hospital, Università di Milano, Via A. di Rudinì, 8, 20142, Milan, Italy.
Tuberous sclerosis complex (TSC) is a complex disease with many different clinical manifestations. Despite the common opinion that TSC is a rare condition, with a mean incidence of 1/6000 live births and a prevalence of 1/20,000, it is increasingly evident that in reality this is not true. Its clinical sequelae span a range of multiple organ systems, in particular the central nervous system, kidneys, skin and lungs. Read More
Investig Clin Urol 2018 Nov 4;59(6):357-362. Epub 2018 Oct 4.
Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Purpose: Classic angiomyolipoma (AML) is common benign kidney tumor. However, some studies have claimed that epithelioid angiomyolipoma (EAML) has malignant potential. We compared the patient characteristics and prognosis of EAML and classic AML to demonstrate predicting factors and poorer prognosis of EAML. Read More
Lab Invest 2018 Oct 18. Epub 2018 Oct 18.
Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Following the publication of this article, the authors noticed an error was in Figure 5C. In the miR-124-3p mimics, the same image was used accidentally for the miR-132-3p mimics. This does not affect the results and conclusions of the article. Read More
Sci Rep 2018 Oct 17;8(1):15601. Epub 2018 Oct 17.
Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. Read More
Int Urol Nephrol 2018 Dec 15;50(12):2131-2137. Epub 2018 Oct 15.
Department of Urology, Istanbul Taksim Gaziosmanpasa Training and Research Hospital, Karayolları Str. No:621, Gaziosmanpaşa, Istanbul, Turkey.
Purpose: The aim of our study was to investigate the impact of the ABO blood groups and blood-based biomarkers on the growth kinetics of renal angiomyolipoma (AML).
Methods: A total of 124 patients with AML who were followed-up between 2010 and 2018 were retrospectively reviewed. The patients' characteristics were recorded, including age, body mass index (BMI), blood pressure, smoking history, and ABO blood group. Read More
Clin Radiol 2018 Oct 9. Epub 2018 Oct 9.
Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada. Electronic address:
This article presents an updated review of cystic renal mass imaging. Most cystic renal masses encountered incidentally are benign and can be diagnosed confidently on imaging and require no follow-up. Hyperattenuating masses discovered at unenhanced or single-phase enhanced computed tomography (CT) measuring between 20-70 HU are indeterminate and can be further investigated first by using ultrasound and, then with multi-phase CT or magnetic resonance imaging (MRI); as the majority represent haemorrhagic/proteinaceous cysts (HPCs). Read More
Am J Med Genet C Semin Med Genet 2018 Sep 11;178(3):365-373. Epub 2018 Oct 11.
Department of Pediatrics, Division of Child Neurology, Cincinnati Childrens Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Between 1993 and 2003, through experiments involving Drosophila sp., cancer biologists identified the protein kinase known as the mammalian target of rapamycin, its pathway, and its relationship to the genes responsible for tuberous sclerosis. Thereafter, clinical research has resulted in regulatory approval of mTOR inhibitors for four distinct manifestations of the disease: giant cell astrocytoma, angiomyolipoma, lymphangioleiomyomatosis, and epilepsy. Read More
Am J Med Genet C Semin Med Genet 2018 Sep 11;178(3):338-347. Epub 2018 Oct 11.
Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre, St. Georges University of London, London, United kingdom.
Tuberous sclerosis complex (TSC) is a tumor predisposition syndrome with significant renal cystic and solid tumor disease. It commonly causes several types of cystic disease and benign tumors (angiomyolipomata) in the kidneys that can both lead to significant premature loss of glomerular filtration rate. The main risks of angiomyolipomata, severe bleeding, loss of renal function, and pulmonary lymphangioleiomyomatosis, can be ameliorated by active surveillance and preemptive therapy with mTOR inhibitors. Read More
Epilepsy Behav 2018 Nov 7;88:357-364. Epub 2018 Oct 7.
Erciyes University Medical School, Department of Pediatrics, Division of Pediatric Neurology, Talas, Kayseri, Turkey. Electronic address:
Purpose: The purpose of this study was to evaluate the long-term results of eight cases diagnosed with tuberous sclerosis complex (TSC) and receiving rapamycin therapy because of epileptic seizures and/or accompanying TSC findings.
Method: Rapamycin therapy was initiated at a dose of 1.5 mg/m. Read More
J Patient Rep Outcomes 2018 Dec 13;2:30. Epub 2018 Jul 13.
6Le Bonheur Children's Hospital and the University of Tennessee, Memphis, TN USA.
Background: Tuberous sclerosis complex (TSC) is a rare genetic disorder characterized by benign tumors in multiple organs, including non-cancerous kidney lesions known as renal angiomyolipomas. This study's objective is to describe the age-stratified morbidity, treatment patterns, and health-related quality of life of TSC patients with renal angiomyolipomas in the United States. A cross-sectional, anonymous web-based survey was conducted with a convenience sample of TSC patients and caregivers identified through a patient advocacy organization. Read More
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;53(9):697-698
Department of Pathology, Shunyi Region Hospital of Beijing, Beijing 101300, China.
J Immunother Cancer 2018 Oct 1;6(1):97. Epub 2018 Oct 1.
Department of Medicine, NYU Langone Health, New York, NY, USA.
Background: Malignant angiomyolipoma is an uncommon tumor of the class of perivasciular epithelioid cell neoplasms (PEComas). These tumors are characteristically driven by deleterious mutations in the tumor suppressors TSC1 and TSC2, whose gene products typically act to inhibit mTOR. There are several cases of malignant angiomyolipoma which exhibit transient responses to mTOR inhibitors, forming the basis of current practice guidelines in malignant PEComa. Read More
J Med Ultrasound 2018 Jul-Sep;26(3):119-122. Epub 2018 Sep 14.
Division of Urology, Department of Surgery, Cathay General Hospital, Taipei, Taiwan.
Angiomyolipoma is one of the renal benign neoplasms. The most of the angiomyolipomas are asymptomatic and found incidentally with ultrasound. They are more prevalent in patients with tuberous sclerosis. Read More
Can J Urol 2018 Oct;25(5):9527-9529
Division of Urology, John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois, USA.
A 37-year-old female presented with abdominal pain. An abdominal computed tomography scan demonstrated a 10 cm x 13 cm left renal mass. An open adrenal-sparing radical nephrectomy was performed. Read More
Int J Surg Case Rep 2018 17;51:404-408. Epub 2018 Sep 17.
Department of Radiology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.
Introduction: Hepatic angiomyolipoma is a rare tumour and is difficult to obtain the accurate diagnosis preoperatively because the imaging features are similar to hepatocellular carcinoma.
Presentation Of Case: We present a case study of an 80-year old woman with a liver tumour measuring 6.2 cm × 6. Read More
Front Med (Lausanne) 2018 11;5:253. Epub 2018 Sep 11.
Riga Stradins University, Riga, Latvia.
Bleeding occurs frequently in liver surgery. Unbalance between tissue plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) concentrations might increase bleeding. Our aim was to analyze perioperative fibrinolytic changes during liver surgery. Read More
Oncotarget 2018 Aug 31;9(68):32900-32916. Epub 2018 Aug 31.
Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, Bio-X Institutes, San Antonio, TX, USA.
Tuberous sclerosis complex (TSC) disease is associated with tumors in many organs, particularly angiomyolipoma (AML) in the kidneys. Loss or inactivation of results in high levels of HIF-α activity and VEGF expression. mTOR inhibitor (rapamycin) and the AMPK activator 5-aminoimidazole-4-carboxamide (AICA)-riboside (AICAR) are currently used separately to treat cancer patients. Read More
AJR Am J Roentgenol 2018 Dec 21;211(6):W288-W296. Epub 2018 Sep 21.
1 Department of Radiology, University of Southern California, 1520 San Pablo St, HC2 L1600, Los Angeles, CA 90033.
Objective: The purpose of this study was to assess the accuracy of a panel of texture features extracted from clinical CT in differentiating benign from malignant solid enhancing lipid-poor renal masses.
Materials And Methods: In a retrospective case-control study of 174 patients with predominantly solid nonmacroscopic fat-containing enhancing renal masses, 129 cases of malignant renal cell carcinoma were found, including clear cell, papillary, and chromophobe subtypes. Benign renal masses-oncocytoma and lipid-poor angiomyolipoma-were found in 45 patients. Read More
Nat Rev Nephrol 2018 Nov;14(11):704-716
Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Tuberous sclerosis complex (TSC) is an autosomal dominant disease characterized by hamartomatous tumours of the brain, heart, skin, lung and kidney. Patients with TSC show a diverse range of neurological features (including seizures, cognitive disability and autism) and renal manifestations (including angiomyolipomas, epithelial cysts and renal cell carcinoma (RCC)). TSC is caused by inactivating mutations in TSC1 and TSC2, which encode hamartin and tuberin, respectively. Read More
Cancer Cytopathol 2018 Sep 7;126(9):782-796. Epub 2018 Sep 7.
Department of Pathology, Stanford University School of Medicine, Stanford, California.
Background: The classification of renal neoplasms is essential for oncologic risk stratification and clinical management, and an accurate pretreatment pathologic diagnosis can provide useful guidance for active surveillance, minimally invasive ablative therapy, or surgical resection and can reduce the incidence of overtreatment. Previous studies evaluating the diagnostic accuracy of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for renal masses are limited and show variable results.
Methods: Two hundred forty-seven renal FNA cases with or without concurrent CNB performed and/or reviewed at the Stanford University School of Medicine over the course of 20 years were identified. Read More
PLoS One 2018 7;13(9):e0201005. Epub 2018 Sep 7.
Schlumberger Moscow Research Center, Moscow Research Institute of Pediatrics and Pediatric Surgery, Moscow, Russian Federation.
Introduction: The EXIST-2 (NCT00790400) study demonstrated the superiority of everolimus over placebo for the treatment of renal angiomyolipomas associated with tuberous sclerosis complex (TSC) or sporadic lymphangioleiomyomatosis (LAM). This post hoc analysis of EXIST-2 study aimed to assess angiomyolipoma tumor behavior among patients who submitted to continued radiographic examination following discontinuation of everolimus in the noninterventional follow-up phase.
Methods: For patients who discontinued everolimus at the completion of extension phase for reasons other than angiomyolipoma progression, a single CT/MRI scan of the kidney was collected after 1 year of treatment discontinuation. Read More
J Coll Physicians Surg Pak 2018 Sep;28(9):S160-S161
Department of Radiology, Civil Hospital and Dow University of Health Sciences, Karachi.
Large aneurysms seen in renal angiomyolipoma are usually more common in patients with tuberous sclerosis in comparison with sporadic cases and they are more prone to hemorrhage ranging from renal hematoma to life-threatening perirenal hemorrhages. We present a case of 13-year female patient who was referred to Civil Hospital, Karachi, with bilateral flank pain, cutaneous nodule and low intelligence. Her color doppler ultrasound revealed pseudoaneurysm in left kidney on the background of bilateral renal angiomyolipomas. Read More
Adv Anat Pathol 2018 Nov;25(6):387-399
Robert J. Tomsich Institute of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH.
Immunohistochemistry may be a very useful adjunct to morphologic diagnosis in many areas of surgical pathology, including genitourinary pathology. In this review, we address common diagnostic dilemmas where immunophenotypic analysis may be utilized and we highlight pitfalls specific to each scenario. For prostate, we review the diagnosis of limited prostatic adenocarcinoma and the distinction of high-grade prostatic adenocarcinoma from urothelial carcinoma. Read More
Cancer Cytopathol 2018 Aug;126 Suppl 8:711-723
Baptist Hospital of Miami and Miami Cancer Institute, Miami, Florida.
An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multilocular cystic RCC [positive] as well as separating chromophobe RCC [diffusely positive] from oncocytoma [focally positive/negative]) and CD117 (separating chromophobe RCC and oncocytoma [positive] from granular variants of clear cell RCC [negative]). Read More
Quant Imaging Med Surg 2018 Jul;8(6):597-608
Department of Radiology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Background: Hepatic epithelioid angiomyolipoma (HEA) shares some similarities with other hepatic tumors, such as hepatocellular carcinoma (HCC). Thus, establishing a definite diagnosis of HEA based on medical imaging is often difficult. In this study, we evaluated multiphasic computed tomography (CT) imaging to differentiate HEA from HCC in patients with noncirrhotic livers. Read More
Int J Urol 2018 Nov 22;25(11):978-979. Epub 2018 Aug 22.
Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan.
Am J Dermatopathol 2018 Sep 17. Epub 2018 Sep 17.
Department of Pathology, Mount Sinai Beth Israel Hospital Center, New York, NY.
Cutaneous angiomyolipoma is a rare mesenchymal tumor, distinct from its renal counterpart. Only few cases have been reported in English language literature to date. Here, we report a case in a 36-year-old man who presented with a painless swelling on his right ear. Read More
Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):717-721
Department of Urology, Peking University People's Hospital, Beijing 100044, China.
Renal angiomyolipoma (AML) is a common benign tumor in the urinary system, mainly composed of adipose tissue, blood vessels and muscle tissue. Renal AML is sporadic in most of patients, while a few are associated with tuberous sclerosis. Classical renal AML occurs predominantly in middle-aged females. Read More
Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):700-704
Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, China.
Objective: To compare the safety and treatment effectiveness of retroperitoneal laparoscopic tumor aspiration and laparoscopic partial nephrectomy (LPN) in the treatment of renal angiomyolipoma (RAML).
Methods: We retrospectively reviewed the clinical data of patients with pathologically confirmed RAML who received operation between August 2010 and August 2016 in the Department of Urology, Peking University First Hospital. Among them, a series of 121 patients were included in this trial according to the inclusion criteria, of which 74 cases could be collected and followed-up effectively. Read More
Diagn Pathol 2018 Aug 16;13(1):53. Epub 2018 Aug 16.
Department of Pathology, Dalian Medical University First Hospital, 222 Zhongshan Road, Xigang District, Dalian, 116011, Liaoning, China.
Background: Primary angiosarcoma of the kidney is a rare and aggressive malignant tumor presenting with a recognizable vascular differentiation. Its prognosis is fatal and the pathogenesis remains unclear. Renal angiomyolipoma is a relatively infrequent renal cortical neoplasm and is composed of variable proportions of adipose tissue, spindle cells, epithelioid smooth muscle cells and abnormal thick-walled blood vessels. Read More
Radiol Case Rep 2018 Oct 7;13(5):982-987. Epub 2018 Aug 7.
Providence-Providence Park Hospital, Medical Education Osteopathic, Division Urology Residency Program/Comprehensive Urology, 16001 West Nine Mile Road, Southfield, MI 48075, USA.
Arteriovenous shunting associated with angiomyolipoma is an unusual entity, which carries important implications to embolization approach. We present a distinctive case involving a 41-year-old woman who presented with retroperitoneal hemorrhage relating to renal angiomyolipoma. During angiography for urgent embolization, a complex vascular supply with arteriovenous shunting was encountered. Read More
Orphanet J Rare Dis 2018 Aug 14;13(1):134. Epub 2018 Aug 14.
Department of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Background: Lymphangioleiomyomatosis (LAM) is a rare lung disease and the mammalian target of the rapamycin (mTOR) inhibitors has been used as an effective therapy. Here we conducted a systematic review and meta-analysis with the aims to quantify the efficacy and safety of mTOR inhibitors in LAM patients.
Methods: The following databases were searched for clinical trials regarding LAM patients treated with mTOR inhibitors until December 2017: Pubmed, Embase, Cochrane Library and OVID medicine. Read More
J Anaesthesiol Clin Pharmacol 2018 Apr-Jun;34(2):280-281
Department of Urology, Fortis Hospital, Noida, Uttar Pradesh, India.
Int Urol Nephrol 2018 Oct 12;50(10):1765-1770. Epub 2018 Aug 12.
Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, 8 Xishiku St, Beijing, 100034, People's Republic of China.
Purpose: To evaluate the efficacy of prophylactic selective arterial embolization (SAE) of angiomyolipomas (AMLs) and to find out predictive factors of significant shrinkage of AMLs after SAE.
Methods: Patients receiving prophylactic SAE for renal AMLs with complete medical records were included. The changes of the size, urine erythrocyte counts, and serum creatinine of all patients pre- and post-embolization were assessed. Read More
Mol Clin Oncol 2018 Aug 15;9(2):226-230. Epub 2018 Jun 15.
Second Department of Propaedeutic Surgery, Laiko General Hospital, 11527 Athens, Greece.
Hepatic epithelioid angiomyolipoma (HEAML) is a rare mesenchymal tumor that has been reported to have malignant potential. We herein describe a rare case of atypical HEAML. A 43-year-old Caucasian male patient visited his general practitioner due to a productive cough persisting for >2 months. Read More
Medicine (Baltimore) 2018 Aug;97(32):e11805
Department of Pathology, First People's Hospital of Wujiang District, Suzhou.
Rationale: Epithelioid angiomyolipoma (EAML) is a subtype of angiomyolipoma with malignant potential. A diagnosis of malignant EAML of the kidney is based on extrarenal metastasis, and predicting early transformation is difficult. To propose criteria for indicators of malignant transformation, herein we report 2 cases and review 17 cases reported in the literature (2000-2017). Read More
Acad Radiol 2018 Aug 4. Epub 2018 Aug 4.
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong, University of Science and Technology, Wuhan, Hubei, China. Electronic address:
Aim: To evaluate the diagnostic value of whole-tumor quantitative apparent diffusion coefficient (ADC) histogram and texture analysis for differentiation of minimal fat angiomyolipoma (MFAML) from clear cell renal cell carcinoma (ccRCC).
Materials And Methods: We retrospectively reviewed 27 patients with MFAML and 113 patients with ccRCC pathologically proven. All patients performed magnetic resonance imaging (MRI) including diffusion-weighted imaging (b = 0, 800s/mm). Read More
Pediatr Radiol 2018 08 4;48(9):1307-1323. Epub 2018 Aug 4.
Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA.
Imaging of tuberous sclerosis complex has rapidly evolved over the last decade in association with increased understanding of the disease process and new treatment modalities. Tuberous sclerosis complex is best known for the neurological symptoms and the associated neuroimaging findings, and children with tuberous sclerosis complex require active surveillance of associated abnormalities in the chest, abdomen and pelvis. Common findings that require regular imaging surveillance are angiomyolipomas in the kidneys and lymphangioleiomyomatosis in the chest. Read More