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BMC Ophthalmol 2020 May 24;20(1):198. Epub 2020 May 24.

Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Medical Artificial Intelligence Research and Verification Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Background: Posterior choroidal leiomyoma is an extremely rare tumor, to our knowledge, less than 10 cases reported in the literature. The definite diagnosis can be confirmed by immunohistochemistry, and local resection is preferable to enucleation for the posterior choroidal leiomyoma.

Case Presentation: Two adult Asian women presented with progressive vision loss in their right eyes. Read More

Acta Neurochir (Wien) 2020 May 23. Epub 2020 May 23.

Medical School of Nankai University, No. 94, Weijin Road, Naikai District, Tianjin, 300071, People's Republic of China.

Background: Pure spinal epidural cavernous malformation (CM) is a rare hypervascular disease that is easily misinterpreted as other imaging-similar epidural lesions. The demographic characteristics, therapeutic strategies, and surgical outcomes associated with this vascular entity remains unclear.

Methods: A retrospective review of patients with pathologically proven, pure epidural CM from 2001 to 2018 was conducted. Read More

Pediatr Dermatol 2020 May 22. Epub 2020 May 22.

Department of Plastic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Infantile hemangioma (IH) is a benign vascular tumor that gradually involutes over several years. Rapidly involuting congenital hemangioma (RICH) is the relatively rare congenital vascular tumor that is fully grown at birth and does not undergo postnatal growth and involutes during the first year. However, after involution of both IH and RICH, some have severe sequelae, such as redundant skin or conspicuous scarring, requiring additional treatment. Read More

J Surg Case Rep 2020 May 15;2020(5):rjaa031. Epub 2020 May 15.

Medico, Ministerio de Salud Publica, Quito, Ecuador.

The lymphangioma is a benign neoplasm, mostly connate, it occurs more often in children. It is more frequently located in the head-neck region, as well as in the armpit, and less frequently in the abdomen. The diagnosis, as well as their appearance is variant, they can be asymptomatic depending on the size. Read More

Childs Nerv Syst 2020 May 20. Epub 2020 May 20.

Department of Neurosurgery, Nagano Children's Hospital, 3100 Toyoshina, Azumino, 399-8288, Japan.

Introduction: Primary intraosseous cavernous hemangiomas of the skull are very rare in the pediatric age group and usually slow-growing tumors.

Case Report: We present a case of 5-month-old girl with a left occipital cavernous hemangioma that is rapidly growing. The subcutaneous occipital tiny mass was first noted at birth, and the lesion became rapidly enlarged in size and became soft for 3 months. Read More

Ann Burns Fire Disasters 2019 Dec;32(4):294-300

National Burns Hospital, Hanoi, Vietnam.

Radiation-induced ulcers are a late-stage skin reaction after radiation therapy for cancer treatment. The present study examined the possibility of using a single-stage reconstructive procedure to manage radiation-related wounds. This prospective study recruited 30 participants who underwent radiation treatment for cancer or hemangioma. Read More

Ophthalmic Plast Reconstr Surg 2020 May 14. Epub 2020 May 14.

Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, New York.

Purpose: To measure orbital cavernous hemangioma size using 3 segmentation methods requiring different degrees of subjective judgment, and to evaluate interobserver agreement using these methods.

Methods: Fourteen patients with orbital cavernous hemangiomas were included in the study. Pretreatment T2-weighted MRIs were analyzed by 2 observers using 3 methods, including 1 user-dependent image segmentation method that required high degrees of subjective judgment (ellipsoid) and 2 parameter-dependent methods that required low degree of subjective judgment (GrowCut and k-means clustering segmentation). Read More

Cureus 2020 May 12;12(5):e8068. Epub 2020 May 12.

Department of Neurosurgery, Shupyk National Medical Academy of Postgraduate Education, Kyiv, UKR.

Cavernous malformations (CMs) of the optic nerves, chiasm, and optic tract are very rare. This report describes a 26-year-old man who presented with recurring headaches, loss of vision in his left eye, and elevated blood pressure. After being diagnosed with glioma of the chiasm, he was referred to our department. Read More

Ann Thorac Cardiovasc Surg 2020 May 18. Epub 2020 May 18.

Department of Thoracic Surgery, Shonan Kamakura General Hospital, Kamakura, Kanagawa, Japan.

We report a surgical case of bronchial artery aneurysm (BAA) that directly connected to a pulmonary artery and a pulmonary vein through an abnormal vessel. It was complicated by racemose hemangioma. This is a rare vascular malformation. Read More

Int J Surg Pathol 2020 May 18:1066896920924120. Epub 2020 May 18.

Queen Elizabeth Hospital, Hong Kong SAR China.

Composite hemangioendothelioma is a rare vascular tumor morphologically comprising several distinct vascular components and exhibits a borderline malignant potential. We described the case of a 53-year-old female who presented with an infiltrative mass in the paravertebral soft tissue. The tumor showed discrete nests of synaptophysin-expressing epithelioid cells accompanied by rich vasculature, features highly reminiscent of sympathetic paraganglioma. Read More

Arch Biochem Biophys 2020 May 13;688:108404. Epub 2020 May 13.

Department of Cardiovascula Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, Guangdong Province, PR China. Electronic address:

Hemangioma (HA) is the most common benign tumor and formed by the proliferating endothelial cells of blood vessels. Interleukins (ILs) have been reported to be critical for HA progression. Our present study found that the expression of IL-10 was decreased in HA cells and tissues as compared to their corresponding controls. Read More

Dig Endosc 2020 May 16. Epub 2020 May 16.

Department of Gastroenterology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.

A 57-year-old female with a history of chronic gastritis presented with a 3-day history of melena and asthenia. Physical examination and laboratory data were normal besides a mild tachycardia and microcytic hypochromic anemia. Gastroscopy showed a 20-mm diameter, bluish submucosal mass at the esophageal entrance, swinging to the hypopharynx once vomit occurred (Fig. Read More

Radiol Med 2020 May 15. Epub 2020 May 15.

Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, South Korea.

Purpose: To determine the intra- and extralesional factors that predict sclerotic degeneration of hepatic hemangiomas in the cirrhotic liver on long-term follow-up computed tomography (CT) examinations.

Materials And Methods: Fifty-seven hepatic hemangiomas (> 5 mm in diameter) in 41 cirrhotic patients, recruited over a 5-year period (January 2005-December 2009), were subjected to CT to determine which factors predict sclerotic contraction or degeneration in hemangiomas. Prior and follow-up CT examinations (from 2000 to 2018) were included to observe time-related changes. Read More

Arch Soc Esp Oftalmol 2020 May 11. Epub 2020 May 11.

Consultores Oftalmológicos, Buenos Aires, Argentina.

Intramuscular cavernous venous malformations affecting extraocular muscles are extremely uncommon. Due to their location, complete resection could be difficult. A clinical case is presented of an inferior rectus muscle orbital cavernous malformation treated with fractionated stereotactic radiotherapy after post-surgical excision recurrence. Read More

JAMA Ophthalmol 2020 May 14;138(5):e191696. Epub 2020 May 14.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

Retina 2020 May 12. Epub 2020 May 12.

Service de Radiothérapie, Centre François Baclesse/ARCHADE-Normandie Université, Caen, France.

Purpose: The aim of this study was to compare the functional and anatomical effectiveness of photodynamic therapy (PDT) versus proton beam therapy (PBT) in a real-life setting for the treatment of circumscribed choroidal hemangioma.

Methods: A total of 191 patients with a diagnosis of circumscribed choroidal hemangioma and treated by PBT or PDT were included for analyses.

Results: The 119 patients (62. Read More

Ear Nose Throat J 2020 May 13:145561320925937. Epub 2020 May 13.

Department of Oral and Maxillofacial Surgery, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China.

Infant hemangioma is a relatively rare congenital disease. Ulcer and infection may occur in some cases. A few cases may develop into deformity and defect. Read More

Acta Chir Belg 2020 May 19:1-4. Epub 2020 May 19.

Department of Thoracic Surgery, CHU St Pierre, Brussels, Belgium.

Pulmonary Sclerosing Pneumocytoma (PSP) is a rare type of benign lung tumor usually encountered in middle-aged Asian women. The lesion is mostly found on routine chest x-rays. Though surgery is recognized as the recommended treatment, there is no consensus on the standard operative procedure for this tumor. Read More

Am J Clin Dermatol 2020 May 11. Epub 2020 May 11.

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltration of the skin and/or mucous membranes, with or without associated blood eosinophilia. The wide range of dermatological manifestations of this spectrum, including nodules and plaques, pustules, blisters, ulcers, and urticarial lesions, is reflected in a non-univocal classification system. We identified six groups of eosinophilic dermatoses based on the predominant anatomic level of involvement: (1) epidermal; (2) of the dermal-epidermal junction; (3) dermal; (4) of the hypodermis and muscle fascia; (5) of the pilosebaceous unit; and (6) vascular/perivascular. Read More

Dig Dis Sci 2020 May 11. Epub 2020 May 11.

Division of Gastroenterology and Hepatology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA.

Dermatol Ther 2020 May 10. Epub 2020 May 10.

Plastic Surgeon, Doctoral Student on Medicine and Sciences of Health in the Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.

Background: Transcutaneous use of dual diode lasers is a new option in dermatology.

Aim: To demonstrate the transcutaneous application of a dual laser in dermatologic outpatients.

Patients And Methods: We used a laser system that combines 980 nm and 1,470 nm wavelengths for treatment of vascular lesions. Read More

Brain Dev 2020 May 7. Epub 2020 May 7.

Department of Paediatric Neurology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.

Background: Congenital disorders of glycosylation (CDG) is a heterogeneous group of congenital metabolic diseases with multisystem clinical involvement. ALG3-CDG is a very rare subtype with only 24 cases reported so far.

Case: Here, we report two siblings with dysmorphic features, growth retardation, microcephaly, intractable epilepsy, and hemangioma in the frontal, occipital and lumbosacral regions. Read More

Curr Pediatr Rev 2020 May 7. Epub 2020 May 7.

Department of Paediatrics, The Chinese University of Hong Kong, and Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital. Hong Kong.

Background: Infantile hemangiomas are the most common vascular tumors of infancy affecting up to 12% of infants by the first year of life.

Objective: To familiarize physicians with the natural history, clinical manifestations, diagnosis, and management of infantile hemangiomas.

Methods: A Pubmed search was conducted in November 2019 in Clinical Queries using the key term 'infantile hemangioma'. Read More

Eur Radiol 2020 May 8. Epub 2020 May 8.

Division of Pediatric Hematology and Oncology, Department of Pediatrics, Dokuz Eylul University School of Medicine, Izmir, Turkey.

Objectives: To evaluate the diagnostic performance of MRI texture analysis (TA) for differentiation of pediatric craniofacial rhabdomyosarcoma (RMS) from infantile hemangioma (IH).

Methods: This study included 15 patients with RMS and 42 patients with IH who underwent MRI before an invasive procedure. All patients had a solitary lesion. Read More

Ophthalmol Retina 2020 May;4(5):544

Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal; Faculdade de Medicina, Universidade de Coimbra (FMUC), Coimbra, Portugal; Association for Biomedical Research and Innovation in Light and Imaging (AIBILI), Coimbra, Portugal.

Am J Forensic Med Pathol 2020 Jun;41(2):138-140

From the Departments of Forensic Medicine and Laboratory of Research LR12SP14.

Cavernous hemangiomas represent the most common benign tumors affecting the liver. They are more often asymptomatic and usually diagnosed through radiological examinations performed for other reasons. When there are symptomatic, they may cause digestive disorders such as abdominal pain, nausea, vomiting, or a palpable mass. Read More

Clin Implant Dent Relat Res 2020 May 7. Epub 2020 May 7.

Oral Pathology Master Programme, Oral and Maxillofacial Pathology Unit, Dental Clinic Service, Department of Stomatology II, University of the Basque Country (UPV/EHU), Leioa, Spain.

Background: Peri-implantitis is the inflammatory process, which most commonly affects the therapy with dental implants. However, there are other reactive and neoplastic entities, mainly benign but also malignant, which also take place in the peri-implant mucosa. There is little information about the histopathological analysis of these peri-implant inflammatory diseases. Read More

Drug Discov Ther 2020 ;14(2):89-92

Department of Dermatology, Wakayama Medical University, Wakayama, Japan.

Infantile hemangioma is a benign cutaneous tumor, which sometimes rapidly enlarges, causes cosmetic problem, destroys normal tissue, and possibly threatens life. Dye lasers, steroid administration, and watchful waiting had been the treatment options for infantile hemangioma, but in recent years propranolol therapy has become available. The mechanism underlying the action of propranolol, however, is still unknown. Read More

Sisli Etfal Hastan Tip Bul 2020 25;54(1):108-112. Epub 2020 Mar 25.

Department of Pediatric Surgery, Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.

Infantile hepatic hemangioma is the most common liver tumor in children. The most common symptoms are mass in her stomach, anemia and heart failure. According to the findings of the patient, the treatment may vary from the clinical follow-up to liver transplantation. Read More

Sisli Etfal Hastan Tip Bul 2019 28;53(3):318-321. Epub 2019 Aug 28.

Department of General Surgery, Medical Park Ankara Hospital, Ankara, Turkey.

Hemangiomas are the most common benign primary hepatic neoplasms, often being incidentally discovered. In most of the cases, they are small, asymptomatic and often require follow up. Giant hemangiomas are known as being larger than 5 cm and mostly consists of a cavernous haemangioma, is usually asymptomatic, diagnosed incidentally. Read More

Front Pediatr 2020 21;8:163. Epub 2020 Apr 21.

Department of Pediatric Cardiology, Heart Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Hepatic arteriovenous fistula (HAVF) is an abnormal communication between the hepatic arteries and hepatic veins. This condition is treated mainly using interventional closure and surgery. However, these procedures are associated with many postoperative complications and high mortality. Read More

Respir Med Case Rep 2020 21;30:101060. Epub 2020 Apr 21.

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.

An asymptomatic 70-year-old woman presented with a nodular lesion overlapping the pulmonary artery at the right hilar region on a chest X-ray. Bronchial arteriography revealed an aneurysmal dilation of the long segment of the right bronchial artery and a shunt from the right bronchial artery to the right lower pulmonary artery. She was diagnosed with primary racemose hemangioma of the bronchial artery (RHBA). Read More

Pathol Int 2020 May 5. Epub 2020 May 5.

Department of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo, Japan.

Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiological distinction from peripheral lung cancers is particularly challenging. Read More

Dermatol Surg 2020 Apr 28. Epub 2020 Apr 28.

Department of Internal Medicine, Division of Dermatology, The Ohio State University, Columbus, Ohio.

J Craniofac Surg 2020 May 4. Epub 2020 May 4.

São Leopoldo Mandic Dental School, Santa Casa de Misericórdia Hospital of São Miguel dos Campos, São Miguel dos Campos, Brazil.

Hemangiomas are benign vascular lesions characterized by endothelial vascular proliferation and may demonstrate aggressive clinical features. Intraosseous hemangiomas are uncommon and the maxillary location rare, with few cases described in the literature. The treatment of these lesions varies, however they have a better prognosis when a surgical treatment through resection is performed. Read More

Chirurgia (Bucur) 2020 Mar-Apr;115(2):267-273

A 52 years old woman, asymptomatic, with no significant medical history, presented to a thoracic surgery department for excision of a giant mediastinal mass that was incidentally detected during a routine abdominal ultrasound. Various imaging methods (echocardiography, chest X-ray, CT-scan, MRI) located the mediastinal mass as paracardiac and the excision using video-assisted thoracoscopic surgery (VATS) was proposed, in general thoracic surgery department. Although initially considered a paracardiac mass, intraoperatively the tumor location proved to be intrapericardial. Read More

J Cutan Pathol 2020 May 3. Epub 2020 May 3.

Dermatopathology Section, Department of Pathology and Laboratory Medicine, VA Consolidated Laboratories, West Roxbury, MA, USA.

Poikilodermatous plaque-like hemangioma (PPLH) is a recently described benign vasoformative entity with only 16 cases reported to date. We present an additional case of a 90-year-old male who presented with a 2-year history of a relatively large, asymptomatic, atrophic plaque on his left buttock. The lesion was initially smaller and grew before stabilizing in size. Read More

Joint Bone Spine 2020 Apr 29. Epub 2020 Apr 29.

Department of Orthopedic Surgery, Trauma Surgery and Spine Therapy, Donau-Ries Klinik Donauwoerth, Germany. Electronic address:

J Neurointerv Surg 2020 Apr 30. Epub 2020 Apr 30.

Sorbonne Université, Paris, France.

Background: Osteolytic lesions of the atlas (C1) are challenging to treat by vertebroplasty due to the vicinity of the vertebral artery and the spinal cord.

Objective: To present our experience with transoral vertebroplasty (TOV) for osteolytic lesions of the lateral mass of the atlas.

Methods: Retrospective case series involving 15 consecutive patients (nine male, six female, mean age 63 years) who underwent TOV for the treatment of an osteolytic lesion of the lateral mass of the atlas. Read More

Clin Imaging 2020 Apr 18;65:24-32. Epub 2020 Apr 18.

Department of Nuclear Medicine, Peking University Third Hospital, 100191 Beijing, PR China. Electronic address:

Purpose: The uptake of F-FDG is higher in most malignancies than in benign tumors. This study aimed to investigate the diagnostic value of F-FDG PET/CT in vertebral vascular tumors.

Materials And Methods: We retrospectively collected PET/CT and clinical data of patients with vertebral vascular tumors and analyzed the location, number, and bone destruction and FDG uptake features of the lesion. Read More

Ear Nose Throat J 2020 Apr 30:145561320922736. Epub 2020 Apr 30.

Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea.

Khirurgiia (Mosk) 2020 (4):65-69

Burnazyan Federal Medical Biophysical Center of FMBA, Moscow, Russia.

We report surgical treatment of a 65-year-old patient with recurrent hemangioendothelioma of inferior and middle segment of inferior vena cava with spread to previously established prosthesis. Advanced resection of inferior vena cava and right-sided nephrectomy were not followed by complications and resulted R0 resection. Surgery time was 180 min. Read More

Cutis 2020 03;105(3):132-136

Division of Dermatology, Loyola University Medical Center, Maywood, Illinois, USA.

Many pediatric skin conditions can be safely monitored with minimal intervention, but certain skin conditions are emergent and require immediate attention and proper assessment of the neonate, infant, or child. We review the following pediatric dermatology emergencies so that clinicians can detect and accurately diagnose these conditions to avoid delayed treatment and considerable morbidity and mortality if missed: staphylococcal scalded skin syndrome (SSSS), impetigo, eczema herpeticum (EH), Langerhans cell histiocytosis (LCH), infantile hemangioma (IH), and IgA vasculitis. Read More

Ital J Pediatr 2020 Apr 29;46(1):54. Epub 2020 Apr 29.

Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.

Background: Although disseminated intravascular coagulation (DIC) is a critical disease, there is few gold standard interventions in neonatal medicine. The aim of this study is to reveal factors affecting neonatal DIC at birth and to assess the effectiveness of rTM and FFP for DIC in neonates at birth.

Methods: We retrospectively evaluated DIC score on the first day of life in neonates with underlying conditions associated with DIC. Read More

Eur J Gastroenterol Hepatol 2020 Apr 27. Epub 2020 Apr 27.

Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine Benha University.

Background: Hepatocellular carcinoma (HCC) has an increasing incidence worldwide, and is considered the second cause of cancer-related death.

Aim: The aim of the study is to assess the usefulness of real-time shear-wave elastography in differentiating HCC from other hepatic focal lesions.

Patients And Methods: The current study was conducted on 110 patients in addition to 10 healthy subjects, divided into four groups as follows: liver cirrhosis, HCC, hepatic focal lesions other than HCC, and control. Read More

Ophthalmol Retina 2020 Apr 25. Epub 2020 Apr 25.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To determine factors predictive of visual outcome in patients with circumscribed choroidal hemangioma treated with photodynamic therapy (PDT).

Design: Retrospective case series.

Participants: Seventy-nine patients with circumscribed choroidal hemangioma treated with PDT. Read More

Can J Urol 2020 Apr;27(2):10192-10194

Department of Urology, Queen's University, Kingston, Ontario.

Adrenal cavernous hemangiomas are a rare, benign, and non-functional tumor. We report a case of a 62-year-old male who presented with right upper quadrant and flank pain. Physical examination revealed a fullness of the right upper quadrant. Read More

Histol Histopathol 2020 Apr 24:18222. Epub 2020 Apr 24.

Department of Cell Biology and Histology, School of Medicine, Campus of International Excellence "Campus Mare Nostrum", IMIB-Arrixaca, University of Murcia, Murcia, Spain.

Intussusceptive angiogenesis (IA) is currently considered an important alternative and complementary form of sprouting angiogenesis (SA). Conversely, intussusceptive lymphangiogenesis (IL) is in an initial phase of study. We compare their morphofunctional characteristics, since many can be shared by both processes. Read More

World J Gastroenterol 2020 Apr;26(14):1674-1682

Department of Gastrointestinal Surgery, Weihai Central Hospital, Weihai 264200, Shandong Province, China.

Background: Gastrointestinal hemangiomas are rare benign tumors. According to the size of the affected vessels, hemangiomas are histologically classified into cavernous, capillary, or mixed-type tumors, with the cavernous type being the most common and racemose hemangiomas being very rare in the clinic. Melena of uncertain origin and anemia are the main clinical manifestations, and other presentations are rare. Read More

Pediatr Dermatol 2020 Apr 23. Epub 2020 Apr 23.

Department of Dermatology, Hospital Sant Joan de Deu, Barcelona, Spain.

Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. Read More