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    Oral Propranolol in a Child with Infantile Hemangioma of the Urethra.
    Urology 2018 Jun 14. Epub 2018 Jun 14.
    Department of Urology, Department of Urology, Graduate School of Medical and Dental, Kagoshima University, Kagoshima, Japan.
    Infantile hemangiomas (IH) are the most common in the head and neck region. They can occur anywhere in the skin, however, urethral hemangiomas are very rare. We describe a case report of a three years old boy with extensive lesions of IH in the anterior urethra. Read More

    Vascular Anomalies.
    J Hand Surg Am 2018 Jun 12. Epub 2018 Jun 12.
    Department of Plastic Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA.
    Vascular anomalies encompass a wide variety of clinical conditions involving the vasculature. Over the past several decades, the terminology has changed as our understanding of these conditions has improved. A well-accepted classification scheme has evolved with constant additions, updates, and revisions. Read More

    Novel association of germline de novo MYH9 mutation with congenital hemangioma.
    Cold Spring Harb Mol Case Stud 2018 Jun 14. Epub 2018 Jun 14.
    Departments of Neurosurgery, Pediatrics, Cellular and Molecular Physiology, Yale School of Medicine
    Congenital hemangiomas are tumor-like vascular malformations with poorly understood pathogenesis. We report the case of a neonate with a massive congenital scalp hemangioma that required urgent neurosurgical removal on the second day of life due to concern for high-flow arteriovenous shunting. Exome sequencing identified a rare damaging de novo germline mutation in MYH9 (c. Read More

    Extracapsular excision of hepatic hemangioma: A single centre experience.
    Ann Hepatobiliary Pancreat Surg 2018 May 30;22(2):101-104. Epub 2018 May 30.
    Department of Gastrointestinal and Hepato-Pancreato-Biliary Surgical Oncology, Tata Memorial Centre, Mumbai, India.
    Backgrounds/aims: Hepatic hemangioma is a common non-epithelial neoplasm of the liver. Presence of symptoms and uncertainty in diagnosis are the most common indications for surgery.

    Methods: Eighteen patients with hepatic hemangioma, operated on from January 2011 to December 2016 at the Hepato-pancreato-biliary surgical unit of Tata Memorial Hospital, were retrospectively analyzed. Read More

    Proximal Ulna: A Rare Location for Solitary Intraosseous Hemangioma.
    Oman Med J 2018 May;33(3):260-263
    Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Yishun, Singapore.
    Intraosseous hemangiomas are rare, benign bone tumors usually affecting the bones of the axial skeleton. Its incidence in the long bones is extremely rare. We report a 19-year-old boy with solitary intraosseous hemangioma of the proximal ulna. Read More

    Masson's Hemangioma of the Urethra: A Case Report.
    Iran J Med Sci 2018 May;43(3):336-339
    Department of Pathology, Ilam University of Medical Sciences, Ilam, Iran.
    Intravascular papillary endothelial hyperplasia (IPEH) is an uncommon benign vascular disease characterized by endothelial cell proliferation and papillary formation within the lumen of blood vessels arising from an organizing thrombus. The occurrence of this uncommon lesion is about 2% of all vascular tumors. IPEH mostly occurs in the 5th decade of life, and there is no gender or age predilection. Read More

    A unique case of recurrent Intracranial Extravascular Papillary Endothelial Hyperplasia following gross total resection and brachytherapy.
    World Neurosurg 2018 Jun 8. Epub 2018 Jun 8.
    Division of Neurosurgery, Rutgers University, Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States, Department of Neurosurgery: 125 Paterson Street, New Brunswick, NJ 08901 United States.
    Background: Extravascular papillary endothelial hyperplasia (EPEH) is an extremely uncommon form of papillary endothelial hyperplasia characterized by an exuberant reactive endothelial proliferation in areas of extravascular hemorrhage rather than within the vascular lumen. Intracranial EPEH is known to develop following radiosurgery in patients with intracranial neoplasms, suggesting a causative relationship between radiotherapy and the development of EPEH. Intracranial EPEH is typically treated with surgical resection, and to date, there have been no reported cases of EPEH recurrence following gross total resection. Read More

    Long term outcome of treatment of vertebral body hemangiomas with direct ethanol injection and short segment stabilization.
    Spine J 2018 Jun 8. Epub 2018 Jun 8.
    Dept of Neuropathology, All India Institute of Medical Sciences, New Delhi (110029).
    Background: Vertebral body (VH) hemangiomas with myelopathy are difficult to manage.

    Objective: To evaluate the role of intra-operative ethanol embolization, surgical decompression and instrumented short segment fusion in VH with myelopathy and long-term outcome (>24 months).

    Methods: Prospective study: Symptomatic VH with cord compression with myelopathy. Read More

    Risk factors for hemoglobinuria after ultrasonography-guided percutaneous microwave ablation for large hepatic cavernous hemangiomas.
    Oncotarget 2018 May 22;9(39):25708-25713. Epub 2018 May 22.
    Department of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, 100853 China.
    Thermal ablation of large hepatic cavernous hemangiomas may lead to intravascular hemolysis, hemoglobinuria, and even acute renal failure. This study aimed to identify the risk factors associated with hemoglobinuria after ultrasonography-guided percutaneous microwave ablation for large hepatic cavernous hemangiomas. In our study, 11 related risk factors were analyzed using univariate and multivariate binary logistic regression model and Receiver operating characteristic curves to determine the contribution to hemoglobinuria after microwave ablation for 49 patients with 51 hepatic cavernous hemangiomas. Read More

    Cavernous Hemangioma Between the Elastomer and Fibrous Capsule of a Breast Implant.
    Aesthetic Plast Surg 2018 Jun 5. Epub 2018 Jun 5.
    Grupo Fleury, Rua Cincinato Braga, 282, Bela Vista, São Paulo, SP, 01333-910, Brazil.
    Hemangiomas are described in many locations, but breast hemangioma (BH) is rare, accounting for only 0.4% of all breast tumors. These tumors are difficult to diagnose preoperatively using conventional imaging modalities because they lack pathognomonic characteristics. Read More

    The impact of pediatric skin disease on self-esteem.
    Int J Womens Dermatol 2018 Mar 12;4(1):27-31. Epub 2017 Dec 12.
    Ann & Robert H. Lurie Children's Hospital, Chicago, IL.
    Background: Pediatric skin disorders can affect children's self-esteem, relationships with caregivers and peers, and performance in school and activities.

    Objective: This review describes common pediatric congenital and acquired dermatologic disorders and the impact that these disorders can have on children's self-esteem.

    Methods: A review of current, English-language literature was conducted with use of the PubMed database. Read More

    Rapidly involuting congenital haemangioma of the liver.
    BMJ Case Rep 2018 Jun 5;2018. Epub 2018 Jun 5.
    Pediatrics, University of Massachusetts Medical School - Baystate, Springfield, MA, USA.
    Rapidly involuting congenital haemangiomas (RICHs) are rare benign vascular tumours of infancy. They are generally asymptomatic, but can present with thrombocytopaenia and coagulopathy. Significant complications including life-threatening bleeding, high-output heart failure and liver failure, though rare, can occur. Read More

    Novel Genotype-Phenotype Correlations in Five Chinese Families with Von Hippel-Lindau Disease.
    Endocr Connect 2018 Jun 5. Epub 2018 Jun 5.
    J Jiang, Department of Urology, Third Military Medical University, Chongqing, China
    Context: Von Hippel-Lindau (VHL) disease manifests as a variety of benign and malignant neoplasms. Previous studies of VHL disease have documented several genotype-phenotype correlations; however, many such correlations are still unknown. Increased identification of new mutations and patients with previously described mutations will allow us to better understand how VHL mutations influence disease phenotypes. Read More

    Adult Laryngeal Ossified Hemangioma: Difficulties in Differential Diagnosis.
    J Craniofac Surg 2018 May 31. Epub 2018 May 31.
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Piemonte Orientale "Amedeo Avogadro," Novara, Italy.
    Adult laryngeal hemangiomas are uncommon and often poorly symptomatic. The authors describe a laryngeal hemangioma with acute airway obstruction and radiologic findings suggesting a chondrosarcoma-like neoplasm, while pathologic features were consistent with an ossified hemangioma. The presence of fields of bone metaplasia into a classical cavernous hemangioma is an unusual phenomenon which, to our knowledge, was never previously described in the larynx. Read More

    Primary Intraosseous Hemangioma of the Foreman Rotundum Area.
    J Craniofac Surg 2018 May 31. Epub 2018 May 31.
    Department of Radiology, The Affiliated Hospital of Qingdao University.
    The primary intraosseous hemangioma is extremely rare in foreman rotundum area. However, it is very important for radiologists and otolaryngologists to be aware of it, in order to be able to provide accurately diagnosis as well choose the best treatment plan. The purpose of this article is to describe imaging features of this kind of tumor. Read More

    Percutaneous vertebroplasty in tumoral spinal fractures with posterior vertebral wall involvement: Feasibility and safety.
    Eur J Radiol 2018 Jul 20;104:38-42. Epub 2018 Apr 20.
    Orthopaedic Surgery Unit, Nice University Hospital, 30 Voie Romaine, 06000 Nice, France.
    Purpose: to evaluate the technical feasibility and safety of CT and fluoroscopy guided percutaneous vertebroplasty in the treatment of tumoral vertebral fractures with posterior wall involvement.

    Materials And Methods: Institutional review board approval and informed consent were obtained for this study. Sixty-three consecutive adult patients (35 women, 28 men; mean age+/- standard deviation: 69 years+/- 14) with tumoral spinal fractures that compromised the posterior wall were treated by means of percutaneous vertebroplasty with CT and fluoroscopy guidance. Read More

    Subcutaneous Lobular Capillary Hemangioma Presenting as a Facial Mass.
    Case Rep Otolaryngol 2018 8;2018:5973619. Epub 2018 May 8.
    Division of Pathology, Children's Health, Dallas, TX, USA.
    Lobular capillary hemangioma is a benign lesion of the skin and mucous membranes. Subcutaneous lobular capillary hemangioma presents as a deeper nodule. Lack of the characteristic surface changes of this subtype of lobular capillary hemangioma makes the clinical diagnosis challenging. Read More

    Renal Pelvic Hemangioma in a 3-Year-Old Boy: a Rare Pediatric Case Report.
    Urology 2018 May 28. Epub 2018 May 28.
    Beijing Children's Hospital, Capital Medical University, Urology Department; Beijing; CN.
    Renal pelvic hemangioma is a rare benign tumor that is difficult to diagnose preoperatively. In the past there are rarely reported cases in children. Here a case of left renal pelvic hemangioma in a 3-year-old boy managed nephrectomy is reported. Read More

    T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling.
    Biochem Biophys Res Commun 2018 Jun 6. Epub 2018 Jun 6.
    Department of Clinical Laboratory, The 3(rd)People's Hospital of Qingdao, Qingdao, 266041, Shandong Province, China. Electronic address:
    Understanding the function and molecular relevance of distinct miRNAs in endothelial cells (ECs) paves avenues for possible therapeutic intervention by targeting epigenetic mechanisms in vascular endothelial dysfunction, one of the major complications of type 2 diabetes mellitus (T2DM). MiR-342-3p, an obesity-associated miRNA, has recently been shown to be significantly upregulated in human angiosarcoma compared to benign hemangioma, indicating its potential involvement as a proangiogenic factor. Herein, we show that endothelial miR-342-3p expression was significantly compromised in T2DM organisms and this inhibition powerfully blocked vasculogenesis in vivo by repressing endothelial proliferation and migration. Read More

    Clinical outcomes and predictors of response to photodynamic therapy in symptomatic circumscribed choroidal hemangioma: A retrospective case series.
    PLoS One 2018 31;13(5):e0197088. Epub 2018 May 31.
    Department of Ophthalmology, Chang Gung Memorial Hospital Linkou Medical Center, Taoyuan, Taiwan.
    Background: To investigate the treatment outcomes and predictors of response to photodynamic therapy (PDT) in patients with symptomatic circumscribed hemangioma (CCH).

    Methods: This retrospective case series examined 20 patients with symptomatic CCH (10 submacular CCHs and10 juxtapapillary CCHs) who underwent standard PDT (wavelength: 662 nm; light dose: 50J/cm2; exposure time: 83 sec) with verteporfin (6mg/m2), either as monotherapy (n = 9) or in association with other treatments (n = 11), of which 7 received intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF). A post-PDT improvement of at least two lines in best-corrected visual acuity (BCVA) was the primary outcome measure. Read More

    Diffuse hepatic epithelioid hemangioendothelioma with multiple splenic metastasis and delayed multifocal bone metastasis after liver transplantation on FDG PET/CT images: A case report.
    Medicine (Baltimore) 2018 Jun;97(22):e10728
    PET-CT Center.
    Rationale: Malignant hepatic epithelioid hemangioendotheliom (HEH) is a rare vascular tumor of endothelial origin, with multiple metastases to the spleen. This report describes a diffuse HEH with splenic metastasis on 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) images and delayed mutifocal bone metastasis after liver transplantation (LTx).

    Patient Concerns: A 30-year-old male was admitted to our hospital with a complaint of abdominal distension, fatigue, and anorexia for 2 months. Read More

    Infantile hemangiomas: what have we learned from propranolol?
    Curr Opin Pediatr 2018 May 24. Epub 2018 May 24.
    Section of Dermatology, Department of Medicine, West Virginia University, Morgantown, West Virginia, USA.
    Purpose Of Review: Infantile hemangiomas are the most common vascular tumor of infancy. Treatment of infantile hemangiomas was revolutionized when propranolol, a nonselective β-blocker, was reported to be effective therapy. In this review, we highlight the lessons learned using propranolol to treat infantile hemangiomas. Read More

    LncRNA SNHG16 drives proliferation, migration, and invasion of hemangioma endothelial cell through modulation of miR-520d-3p/STAT3 axis.
    Cancer Med 2018 May 29. Epub 2018 May 29.
    Shanghai Fourth People's Hospital, Shanghai, China.
    It has been verified that long noncoding RNAs (lncRNAs) have great effects on various biological behaviors of human diseases. Although more and more lncRNAs have been studied in human cancers, countless lncRNAs still need to be excavated. This study aims to investigate the impacts of lncRNA SNHG16 on proliferation and metastasis of human hemangioma endothelial cell (HemECs). Read More

    Safety of Oral Propranolol for Infantile Hemangioma.
    Pediatrics 2018 Jun;141(6)
    University of Rennes, Rennes, France.
    Objectives: The safety of oral propranolol for infantile hemangioma has not yet been studied at population level since the pediatric use marketing authorization was obtained in Europe.

    Methods: A survey of a nationwide, claim-based observational cohort of children <3 years old, with at least 1 delivery of oral propranolol between July 2014 and June 2016, was performed by using the database of the French National Health Insurance system. Standardized morbidity ratios (SMRs) were calculated by using, from the same database, a representative random sample of nonexposed subjects. Read More

    Bone transport for reconstruction of large bone defects after tibial tumor resection: a report of five cases.
    J Int Med Res 2018 Jan 1:300060518774992. Epub 2018 Jan 1.
    Department of Orthopaedics, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
    This study was performed to explore the clinical efficacy of bone transport using external fixation for treatment of large bone defects after tibial tumor resection in five patients. Bone transport started 14 days postoperatively at 1 mm/day and was adjusted according to the callus-to-diameter ratio. The bone transport time, bone graft fusion, relapse, and metastasis were recorded. Read More

    Curative effect and safety of propranolol combined with prednisone in the treatment of infantile hemangiomas.
    Exp Ther Med 2018 Jun 4;15(6):4677-4682. Epub 2018 Apr 4.
    Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China.
    The object of this study was to analyze the curative effect and safety of propranolol combined with prednisone in the treatment of infantile hemangiomas (IHs). Forty-four children with IHs on the head and face at the proliferative phase admitted to Jinan Center Hospital Affiliated to Shandong University were randomly divided into two groups. Children in group A took orally propranolol 2 mg/kg/day in three divided doses combined with prednisone 2 mg/kg/day in two divided doses in the first two weeks; children in group B took orally propranolol alone, and the dose was the same as that in group A. Read More

    [Radiographic analysis for infarcted angiomatous polyps in maxillary sinus].
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Aug;31(15):1164-1167
    Department of Otorhinolaryngology Head and Neck Surgery, Shengjing Hospital Affiliated to China Medical University, Shenyang, 110004, China.
    To explore the CT, MRI manifestations of the polyp of maxillary sinus cavernous hemangioma. To summarize the imaging characteristics and it may assist doctors to diagnose infarcted angiomatous polyps in maxillary sinus with further developing.A retrospective analysis of the CT, MRI manifestations and clinical analysis about 27 cases confirmed by surgery pathology who are maxillary sinus cavernous hemangioma. Read More

    [The relationship between pathology and imaging overview in pediatric nasal tumors].
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Oct;31(20):1570-1574
    Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
    To study the clinical features and nasal image of children with nasal tumors.The samples of 40 cases of pediatric nasal tumors, which were diagnosed based on pathology, were collected. Clinical features, pathological histology and imaging characteristics were also summarized. Read More

    Sudden spinal hemorrhage in a pediatric case with total body irradiation-induced cavernous hemangioma.
    Pediatr Blood Cancer 2018 May 24:e27250. Epub 2018 May 24.
    Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
    Compared to cerebral radiation-induced cavernous hemangiomas (RICHs), little is known about intraspinal RICHs. A 13-year-old male suddenly developed symptomatic spinal hemorrhage eight years after hematopoietic stem cell transplantation using a total body irradiation (TBI) based myeloablative regimen. A solitary small hemangioma was detected on follow-up T2 star weighted magnetic resonance imaging of the spine. Read More

    Cardiac diagnostics before oral propranolol therapy in infantile hemangioma: retrospective evaluation of 234 infants.
    World J Pediatr 2018 May 23. Epub 2018 May 23.
    Division of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery, University Hospital of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
    Background: The indication and extent of cardiac screening before oral propranolol therapy (OPT) in patients with infantile hemangioma (IH) has been challenged. In this study, we evaluated pre-OPT cardiac diagnostics in a pediatric IH cohort in our department.

    Methods: Retrospective chart review of infants ≤ 12 months old with IH undergoing OPT. Read More

    Dye laser treatment for hemorrhagic vascular lesions.
    Laser Ther 2018 Mar;27(1):61-64
    Department of pediatric surgery, Dokkyo Medical University Koshigaya Hospital.
    Background And Aims: It is generally thought that bleeding from a hemangioma is difficult to stop. With development of the long pulse dye laser (LPDL), it has become possible to treat hemangioma with a large blood vessel diameter. Thus, it is effective in treating infantile hemangioma and pyogenic granuloma. Read More

    Expression profile of circular RNAs in infantile hemangioma detected by RNA-Seq.
    Medicine (Baltimore) 2018 May;97(21):e10882
    Department of Plastic and Cosmetic Surgery, Maternal and Child Health Medical Institute, The Affiliated Obstetrics and Gynecology Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
    Background: Circular RNAs (circRNAs) have emerged as a novel class of widespread non-coding RNAs, and they play crucial roles in various biological processes. However, the characterization and function of circRNAs in infantile hemangioma (IH) remain elusive.

    Methods: In this study, we used RNA-Seq and circRNA prediction to study and characterize the circRNAs in IH tissue and a matched normal skin control. Read More

    Serum concentrations of VEGF and bFGF in the course of propranolol therapy of infantile hemangioma in children - are we closer to understand the mechanism of action of propranolol on hemangiomas?
    Adv Clin Exp Med 2018 May 16. Epub 2018 May 16.
    Department of Pediatric Surgery and Urology, Wroclaw Medical University, Poland.
    Background: Propranolol has become the treatment of choice for infantile hemangiomas (IH). Neither the pathogenesis of IH nor the mechanism of action of propranolol on them are well understood. Possible explanations include the inhibition of angiogenesis by decreasing vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), induction of vascular endothelial cell apoptosis and vasoconstriction. Read More

    Efficacy and absorption of topical sirolimus for the treatment of vascular anomalies in children: A case series.
    Pediatr Dermatol 2018 May 23. Epub 2018 May 23.
    Department of General Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, QC, Canada.
    Background/objectives: Efficacy of topical sirolimus has recently been described in lymphatic anomalies but not in other types of vascular anomalies. To our knowledge, systemic absorption of topical sirolimus in these lesions has not yet been reported. The objective was to evaluate the efficacy, tolerance, and absorption of topical sirolimus 0. Read More

    Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens.
    Poult Sci 2018 May 19. Epub 2018 May 19.
    College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
    There was an outbreak of hemangioma associated with avian leukosis virus subgroup J (ALV-J) between 2006 and 2010 in China in commercial layer chickens. Recently, severe hemangiomas broke out in Hy-Line layer chickens on a poultry farm in 2017 where ALV was eradicated earlier. Six isolates of ALV-J, named SDAU1701-SDAU1706, were characterized by virus isolation and sequence analysis of the complete proviral genomes. Read More

    Blaschko-linear "Congenital Mixed Hemato-lymphangio-keratoma Serpiginosum" Naeviforme: A New Hybrid Entity or Various Morphological Reflections of the Two Different Vascular Abnormalities?
    J Clin Aesthet Dermatol 2018 May 1;11(5):43-47. Epub 2018 May 1.
    Dr. Tas is with the Health Sciences University, Istanbul Bagcilar Research and Training Hospital, Department of Dermatology in Istanbul, Turkey.
    We present the case of a 15-year-old girl who presented with an unusual grouping of lesions on her upper left leg. The lesions had been present since birth. The patient had five different types of lesions: 1) transparent grouped or scattered yellowish vesicles; 2) keratotic-surfaced, grouped dark-yellowish papules; 3) bright-red grouped papules; 4) keratotic-surfaced grouped dark-red papules; and 5) patchy, punctate, and erythematous red macules. Read More

    Spindle Cell Hemangioma in the Mucosa of the Upper Lip: A Case Report and Review of the Literature.
    Case Rep Dent 2018 26;2018:1370701. Epub 2018 Mar 26.
    Department of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Nara, Japan.
    Spindle cell hemangioma (SCH) is a unique benign vascular lesion. We present a case of SCH in the upper lip of a 41-year-old woman. A submucosal nodular mass 30 × 20 mm in size was observed in the left upper lip. Read More

    Robot-assisted radiofrequency ablation of a sacral S1-S2 aggressive hemangioma.
    World Neurosurg 2018 May 16. Epub 2018 May 16.
    Department of Neurosurgery, Amiens University Hospital, Picardie. Electronic address:
    Aggressive vertebral hemangiomas are rare tumors of the spine. The treatment management strategy usually consists of vertebroplasty, radiation therapy or in rare cases of surgical strategy. We present a case of a bulging sacral S1-S2 hemangioma in the spinal canal that could not be managed in the usual manner. Read More

    Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma.
    Eye (Lond) 2018 May 18. Epub 2018 May 18.
    Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
    Purpose: To describe the vascular changes of circumscribed choroidal hemangioma (CCH) after ruthenium-106 brachytherapy using optical coherence tomography angiography (angio-OCT).

    Methods: Seven eyes of 7 patients diagnosed with symptomatic CCH who underwent ruthenium-106 plaque radiotherapy were included in the study. Patients underwent complete ophthalmic examination, bulbar echography and angio-OCT. Read More

    [Fibrous hemangioma of esophagus portal: a case report].
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 May;31(10):806-807
    A 33 year old male patient has found in the oral cavity tumor with nausea and vomiting after 20 days ago. The patients feel pharyngeal foreign body sensation, occasional sense of suffocation, the oropharyngeal tumor disappeared and foreign body sensation disappeared after swallowing. The patients without angina, no hemoptysis, no hoarseness, no acid reflux symptoms and weight loss phenomenon. Read More

    Propranolol induces hemangioma endothelial cell apoptosis via a p53‑BAX mediated pathway.
    Mol Med Rep 2018 May 14. Epub 2018 May 14.
    Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University Xi'an, Shaanxi 710004, P.R. China.
    The use of propranolol for the treatment of infantile hemangioma (IH) has been widely investigated in recent years. However, the underlying therapeutic mechanism of propranolol for the treatment of IH remains poorly understood. The aim of the present study was to investigate the expression of proteins regulated by cellular tumor antigen p53 (p53) in associated apoptosis pathways in IH endothelial cells (HemECs) treated with propranolol. Read More

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