Echocardiographic and clinical findings in patients with Fabry disease during long-term enzyme replacement therapy: a nationwide Danish cohort study.
- Christoffer Valdorff Madsen,
- Henning Bundgaard,
- Åse Krogh Rasmussen,
- Søren Schwartz Sørensen,
- Jørgen Holm Petersen,
- Lars Køber,
- Ulla Feldt-Rasmussen,
- Helle Petri
Scand Cardiovasc J 2017 May 25:1-10. Epub 2017 May 25.
e Department of Cardiology , Copenhagen University Hospital, Rigshospitalet , Copenhagen , Denmark.
Objectives: In patients with Fabry disease (FD), left ventricular hypertrophy and arrhythmias are frequently observed and cardiac involvement is the leading cause of death. Long-term efficacy of enzyme replacement therapy (ERT) on cardiac involvement is unclear. We assessed and compared long-term progression of cardiac involvement according to ERT and non-ERT. Read More